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Wyszukujesz frazę ""Gene Expression Regulation, Developmental"" wg kryterium: Temat


Tytuł :
The porcine cerebellin gene family.
Autorzy :
Larsen K; Department of Molecular Biology and Genetics, Aarhus University, C.F. Møllers Allé 3, DK-8000 Aarhus C, Denmark. Electronic address: .
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Źródło :
Gene [Gene] 2021 Oct 05; Vol. 799, pp. 145852. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Brain/*embryology
Nerve Tissue Proteins/*genetics
Animals ; Brain/physiology ; Cloning, Molecular ; Female ; Glycosylation ; Multigene Family ; Nerve Tissue Proteins/metabolism ; Open Reading Frames ; Protein Precursors/genetics ; Swine
Czasopismo naukowe
Tytuł :
Identification, characterization and mRNA transcript abundance profiles of the carboxylesterase (CXE5) gene in Eriocheir sinensis suggest that it may play a role in methyl farnesoate degradation.
Autorzy :
Li X; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China. Electronic address: .
Chen T; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Xu R; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Huang M; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Huang J; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Xie Q; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Liu F; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Su S; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Ma K; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Engineering Research Center of Aquaculture (Shanghai Ocean University), Shanghai 201306, China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110630. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Arthropod Proteins/*metabolism
Brachyura/*enzymology
Carboxylesterase/*metabolism
Fatty Acids, Unsaturated/*metabolism
Hemolymph/*metabolism
RNA, Messenger/*metabolism
Animals ; Arthropod Proteins/genetics ; Brachyura/genetics ; Brachyura/growth & development ; Carboxylesterase/genetics ; Phylogeny ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
Identification and functional analysis of a sex-biased transcriptional factor Foxl2 in the bay scallop Argopecten irradians irradians.
Autorzy :
Ning J; Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China. Electronic address: .
Cao W; College of Marine Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Lu X; Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Chen M; Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Liu B; College of Marine Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Wang C; Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China; College of Marine Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110638. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Fish Proteins/*metabolism
Forkhead Box Protein L2/*metabolism
Pectinidae/*metabolism
Amino Acid Sequence ; Animals ; Base Sequence ; Fish Proteins/genetics ; Forkhead Box Protein L2/genetics ; Gene Expression Profiling ; Pectinidae/genetics ; Pectinidae/growth & development ; Phylogeny ; Sequence Homology ; Sex Factors
Czasopismo naukowe
Tytuł :
Molecular characterization and function of chitin deacetylase-like from the Chinese mitten crab, Eriocheir sinensis.
Autorzy :
Li X; Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, PR China; Jiangsu Key Laboratory of Marine Biotechnology, Jiangsu Ocean University, Lianyungang, 222005, PR China. Electronic address: .
Diao P; Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, PR China; Jiangsu Key Laboratory of Marine Biotechnology, Jiangsu Ocean University, Lianyungang, 222005, PR China. Electronic address: .
Chu J; Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, PR China; Jiangsu Key Laboratory of Marine Biotechnology, Jiangsu Ocean University, Lianyungang, 222005, PR China. Electronic address: .
Zhou G; Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, PR China.
Zhou J; Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, PR China.
Lin H; Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, PR China.
Chen J; Jiangsu Key Laboratory of Marine Biotechnology, Jiangsu Ocean University, Lianyungang, 222005, PR China.
Zeng Q; State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, PR China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110612. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Gene Expression Regulation, Enzymologic*
Amidohydrolases/*metabolism
Arthropod Proteins/*metabolism
Brachyura/*enzymology
Amidohydrolases/genetics ; Amino Acid Sequence ; Animals ; Molting ; Phylogeny ; Sequence Homology
Czasopismo naukowe
Tytuł :
Dact1 is expressed during chicken and mouse skeletal myogenesis and modulated in human muscle diseases.
Autorzy :
Contriciani RE; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
da Veiga FC; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
do Amaral MJ; Faculty of Pharmacy, Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil.
Castelucci BG; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
de Sousa LM; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
de Jesus MB; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
Consonni SR; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
Collares-Buzato CB; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
Mermelstein C; Biomedical Sciences Institute, Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil.
Dietrich S; Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, Portsmouth, UK.
Alvares LE; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110645. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Muscle Development*
Adaptor Proteins, Signal Transducing/*metabolism
Muscle, Skeletal/*metabolism
Muscular Diseases/*metabolism
Myoblasts/*metabolism
Nuclear Proteins/*metabolism
RNA-Binding Proteins/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Animals ; Cell Differentiation ; Cell Nucleus/metabolism ; Cell Proliferation ; Chickens ; Female ; Humans ; Mice ; Muscle, Skeletal/cytology ; Muscular Diseases/pathology ; Myoblasts/cytology ; Nuclear Proteins/genetics ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
A piRNA-lncRNA regulatory network initiates responder and trailer piRNA formation during mosquito embryonic development.
Autorzy :
Betting V; Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Joosten J; Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Halbach R; Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Thaler M; Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Miesen P; Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Van Rij RP; Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Oct; Vol. 27 (10), pp. 1155-1172. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Gene Silencing*
Aedes/*genetics
Embryonic Development/*genetics
RNA, Long Noncoding/*genetics
RNA, Small Interfering/*genetics
Aedes/embryology ; Aedes/metabolism ; Animals ; Base Pairing ; Base Sequence ; Conserved Sequence ; Embryo, Nonmammalian ; Gene Regulatory Networks ; Insect Proteins/genetics ; Insect Proteins/metabolism ; RNA, Long Noncoding/metabolism
Czasopismo naukowe
Tytuł :
Expression of long-chain polyunsaturated fatty acids biosynthesis genes during the early life-cycle stages of the tropical gar Atractosteus tropicus.
Autorzy :
De la Cruz-Alvarado FJ; Laboratorio de Acuicultura Tropical, DACBIOL-UJAT, Carretera Villahermosa-Cárdenas KM 0.5, C.P.86139 Villahermosa, Tabasco, Mexico.
Álvarez-González CA; Laboratorio de Acuicultura Tropical, DACBIOL-UJAT, Carretera Villahermosa-Cárdenas KM 0.5, C.P.86139 Villahermosa, Tabasco, Mexico.
Llera-Herrera R; Instituto de Ciencias del Mar y Limnología - Unidad Académica Mazatlán, Universidad Nacional Autónoma de México, Joel Montes Camarena S/N, PO Box 811, Mazatlán, Sinaloa, Mexico.
Monroig Ó; Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones Científicas (IATS-CSIC), 12595 Ribera de Cabanes, Castellón, Spain.
Kabeya N; Department of Marine Biosciences, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato-ku, Tokyo 108-8477, Japan.
Rodríguez-Morales S; Facultad de Química, Universidad Nacional Autónoma de México, Unidad de Química-Sisal, Puerto de Abrigo s/n, Sisal, Yucatán, Mexico.
Concha-Frias B; División Académica Multidisciplinaria de Jalpa de Méndez, Universidad Juárez Autónoma de Tabasco, Carretera Nacajuca-Jalpa de Méndez R/a Rivera Alta, C.P. 86200 Jalpa de Méndez, Tabasco, Mexico.
Guerrero-Zárate R; Laboratorio de Acuicultura Tropical, DACBIOL-UJAT, Carretera Villahermosa-Cárdenas KM 0.5, C.P.86139 Villahermosa, Tabasco, Mexico.
Jiménez-Martínez LD; División Académica Multidisciplinaria de Jalpa de Méndez, Universidad Juárez Autónoma de Tabasco, Carretera Nacajuca-Jalpa de Méndez R/a Rivera Alta, C.P. 86200 Jalpa de Méndez, Tabasco, Mexico. Electronic address: .
Peña-Marín ES; Laboratorio de Acuicultura Tropical, DACBIOL-UJAT, Carretera Villahermosa-Cárdenas KM 0.5, C.P.86139 Villahermosa, Tabasco, Mexico; Consejo Nacional de Ciencia y Tecnología, CDMX, Mexico. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110628. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Lipogenesis*
Fatty Acid Desaturases/*genetics
Fatty Acid Elongases/*genetics
Fatty Acids, Unsaturated/*biosynthesis
Fish Proteins/*metabolism
Fishes/*metabolism
Animals ; Fish Proteins/genetics ; Fishes/genetics ; Fishes/growth & development ; Transcriptome
Czasopismo naukowe
Tytuł :
miR-133b targets tagln2 and functions in tilapia oogenesis.
Autorzy :
Ma Z; Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China.
Yang J; Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China.
Zhang Q; Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China.
Xu C; Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China.
Wei J; Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China.
Sun L; Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China.
Wang D; Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China. Electronic address: .
Tao W; Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110637. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Oogenesis*
Fish Proteins/*metabolism
MicroRNAs/*genetics
Microfilament Proteins/*metabolism
Ovary/*metabolism
Tilapia/*metabolism
Animals ; Female ; Fish Proteins/genetics ; Forkhead Box Protein L2/genetics ; Forkhead Box Protein L2/metabolism ; Gene Expression Profiling ; Microfilament Proteins/genetics ; Ovary/cytology ; Tilapia/genetics ; Tilapia/growth & development
Czasopismo naukowe
Tytuł :
Differential expression of PEPCK isoforms is correlated to Aedes aegypti oogenesis and embryogenesis.
Autorzy :
da Silva RM; Laboratório Integrado de Bioquímica Hatisaburo Masuda and Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, RJ, Brazil; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular, Rio de Janeiro, RJ, Brazil.
Vital WO; Laboratório Integrado de Bioquímica Hatisaburo Masuda and Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, RJ, Brazil.
Martins RS; Programa de computação científica, Instituto Oswaldo Cruz, IOC, Brazil.
Moraes J; Laboratório Integrado de Bioquímica Hatisaburo Masuda and Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, RJ, Brazil.
Gomes H; Laboratório Integrado de Bioquímica Hatisaburo Masuda and Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, RJ, Brazil.
Calixto C; Laboratório Integrado de Bioquímica Hatisaburo Masuda and Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, RJ, Brazil.
Konnai S; Laboratory of Infectious Diseases, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Kita-ku Sapporo 060-0818, Japan.
Ohashi K; Laboratory of Infectious Diseases, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Kita-ku Sapporo 060-0818, Japan.
da Silva Vaz I Jr; Centro de Biotecnologia and Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Logullo C; Laboratório Integrado de Bioquímica Hatisaburo Masuda and Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, RJ, Brazil; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular, Rio de Janeiro, RJ, Brazil. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110618. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Embryonic Development*
Gene Expression Regulation, Developmental*
Gluconeogenesis*
Oogenesis*
Cytosol/*metabolism
Glucose/*metabolism
Phosphoenolpyruvate Carboxykinase (ATP)/*metabolism
Aedes ; Amino Acid Sequence ; Animals ; Phosphoenolpyruvate Carboxykinase (ATP)/genetics ; Phylogeny ; Protein Isoforms ; Sequence Homology
Czasopismo naukowe
Tytuł :
RNA interference of mTOR gene delays molting process in Eriocheir sinensis.
Autorzy :
Hou X; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China.
Yang H; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China.
Chen X; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China; Department of Pharmacy, School of Medicine, Tongji University, 1239 Siping Road, Shanghai, PR China.
Wang J; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China. Electronic address: .
Wang C; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110651. Date of Electronic Publication: 2021 Jul 25.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Molting*
RNA Interference*
RNA, Small Interfering/*genetics
TOR Serine-Threonine Kinases/*antagonists & inhibitors
Animals ; Brachyura ; Signal Transduction ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Characterization, expression, and regulatory effects of nr0b1a and nr0b1b in spotted scat (Scatophagus argus).
Autorzy :
Shi H; Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Key Laboratory of Marine Ecology and Aquaculture Environment of Zhanjiang, Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Fisheries College, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Ocean University, Zhanjiang 524088, China.
Ru X; Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Key Laboratory of Marine Ecology and Aquaculture Environment of Zhanjiang, Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Fisheries College, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Ocean University, Zhanjiang 524088, China.
Mustapha UF; Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Key Laboratory of Marine Ecology and Aquaculture Environment of Zhanjiang, Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Fisheries College, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Ocean University, Zhanjiang 524088, China.
Jiang D; Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Key Laboratory of Marine Ecology and Aquaculture Environment of Zhanjiang, Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Fisheries College, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Ocean University, Zhanjiang 524088, China.
Huang Y; Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Key Laboratory of Marine Ecology and Aquaculture Environment of Zhanjiang, Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Fisheries College, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Ocean University, Zhanjiang 524088, China.
Pan S; Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Key Laboratory of Marine Ecology and Aquaculture Environment of Zhanjiang, Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Fisheries College, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Ocean University, Zhanjiang 524088, China.
Zhu C; Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Key Laboratory of Marine Ecology and Aquaculture Environment of Zhanjiang, Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Fisheries College, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Ocean University, Zhanjiang 524088, China.
Li G; Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Key Laboratory of Marine Ecology and Aquaculture Environment of Zhanjiang, Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Fisheries College, Guangdong Research Center on Reproductive Control and Breeding Technology of Indigenous Valuable Fish Species, Guangdong Ocean University, Zhanjiang 524088, China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110644. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
DAX-1 Orphan Nuclear Receptor/*metabolism
Fish Proteins/*metabolism
Fishes/*metabolism
Ovary/*metabolism
Testis/*metabolism
Amino Acid Sequence ; Animals ; DAX-1 Orphan Nuclear Receptor/genetics ; Female ; Fish Proteins/genetics ; Fishes/genetics ; Male ; Ovary/cytology ; Sequence Homology ; Sex Factors ; Testis/cytology
Czasopismo naukowe
Tytuł :
Integrated analysis of blood mRNAs and microRNAs reveals immune changes with age in the Yangtze finless porpoise (Neophocaena asiaeorientalis).
Autorzy :
Yin D; Shanghai Universities Key Laboratory of Marine Animal Taxonomy and Evolution, Shanghai Ocean University, Shanghai 201306, China; Scientific Observing and Experimental Station of Fishery Resources and Environment in the Lower Reaches of the Changjiang River, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, CAFS, WuXi 214081, China.
Lin D; Scientific Observing and Experimental Station of Fishery Resources and Environment in the Lower Reaches of the Changjiang River, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, CAFS, WuXi 214081, China.
Guo H; Shanghai Universities Key Laboratory of Marine Animal Taxonomy and Evolution, Shanghai Ocean University, Shanghai 201306, China.
Gu H; Shanghai Universities Key Laboratory of Marine Animal Taxonomy and Evolution, Shanghai Ocean University, Shanghai 201306, China.
Ying C; Scientific Observing and Experimental Station of Fishery Resources and Environment in the Lower Reaches of the Changjiang River, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, CAFS, WuXi 214081, China.
Zhang Y; Shanghai Universities Key Laboratory of Marine Animal Taxonomy and Evolution, Shanghai Ocean University, Shanghai 201306, China.
Zhang J; Scientific Observing and Experimental Station of Fishery Resources and Environment in the Lower Reaches of the Changjiang River, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, CAFS, WuXi 214081, China.
Liu K; Scientific Observing and Experimental Station of Fishery Resources and Environment in the Lower Reaches of the Changjiang River, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, CAFS, WuXi 214081, China. Electronic address: .
Tang W; Shanghai Universities Key Laboratory of Marine Animal Taxonomy and Evolution, Shanghai Ocean University, Shanghai 201306, China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110635. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Transcriptome*
MicroRNAs/*genetics
Porpoises/*immunology
RNA, Messenger/*genetics
Age Factors ; Animals ; MicroRNAs/blood ; Porpoises/blood ; Porpoises/genetics ; RNA, Messenger/blood
Czasopismo naukowe
Tytuł :
Characterization of the foxl2 gene involved in the vtg expression in mud crab (Scylla paramamosain).
Autorzy :
Wan H; Key Laboratory of Healthy Mariculture for the East China Sea, Ministry of Agriculture and Rural Affairs, Fisheries College, Jimei University, Xiamen 361021, China; Fujian Engineering Research Center of Aquatic Breeding and Healthy Aquaculture, Xiamen 361021, China.
Zhong J; Key Laboratory of Healthy Mariculture for the East China Sea, Ministry of Agriculture and Rural Affairs, Fisheries College, Jimei University, Xiamen 361021, China; Fujian Engineering Research Center of Aquatic Breeding and Healthy Aquaculture, Xiamen 361021, China.
Zhang Z; College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Key Laboratory of Marine Biotechnology of Fujian Province, Institute of Oceanology, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Xie Y; Key Laboratory of Healthy Mariculture for the East China Sea, Ministry of Agriculture and Rural Affairs, Fisheries College, Jimei University, Xiamen 361021, China; Fujian Engineering Research Center of Aquatic Breeding and Healthy Aquaculture, Xiamen 361021, China.
Wang Y; Key Laboratory of Healthy Mariculture for the East China Sea, Ministry of Agriculture and Rural Affairs, Fisheries College, Jimei University, Xiamen 361021, China; Fujian Engineering Research Center of Aquatic Breeding and Healthy Aquaculture, Xiamen 361021, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Sep 25; Vol. 798, pp. 145807. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Brachyura/*genetics
Forkhead Box Protein L2/*genetics
Vitellogenins/*genetics
Amino Acid Sequence ; Animals ; Brachyura/growth & development ; Crustacea/genetics ; Crustacea/growth & development ; Female ; Gene Expression Profiling ; Male ; Ovary/growth & development ; Ovary/metabolism ; Phylogeny ; Polymerase Chain Reaction ; Protein Domains ; Sequence Alignment ; Testis/metabolism ; Tissue Distribution ; Vitellogenins/biosynthesis
Czasopismo naukowe
Tytuł :
Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity.
Autorzy :
Malkmus J; Developmental Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.
Ramos Martins L; Developmental Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.
Jhanwar S; Developmental Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.; Swiss Institute for Bioinformatics, University of Basel, Basel, Switzerland.
Kircher B; Department of Biology, University of Florida, Gainesville, FL, USA.
Palacio V; Developmental Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.
Sheth R; Developmental Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.
Leal F; Department of Biology, University of Florida, Gainesville, FL, USA.
Duchesne A; Université Paris-Saclay, INRAE, AgroParisTech, GABI, Jouy-en-Josas, France.
Lopez-Rios J; Development and Evolution, Centro Andaluz de Biología del Desarrollo, CSIC-Universidad Pablo de Olavide-Junta de Andalucía, Seville, Spain.
Peterson KA; The Jackson Laboratory, Bar Harbor, ME, USA.
Reinhardt R; Developmental Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.
Onimaru K; Laboratory for Bioinformatics Research, RIKEN BDR, Wako City, Saitama, Japan.
Cohn MJ; Department of Biology, University of Florida, Gainesville, FL, USA.; Department of Molecular Genetics and Microbiology, Genetics Institute, University of Florida, Gainesville, FL, USA.
Zuniga A; Developmental Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland. .
Zeller R; Developmental Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 21; Vol. 12 (1), pp. 5557. Date of Electronic Publication: 2021 Sep 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Enhancer Elements, Genetic*
Gene Expression Regulation, Developmental*
Animal Fins/*metabolism
Intercellular Signaling Peptides and Proteins/*genetics
Limb Buds/*metabolism
Animal Fins/cytology ; Animal Fins/growth & development ; Animals ; Base Sequence ; Biological Evolution ; Boidae ; Cattle ; Chickens ; Embryo, Mammalian ; Embryo, Nonmammalian ; Iguanas ; Intercellular Signaling Peptides and Proteins/metabolism ; Limb Buds/cytology ; Limb Buds/growth & development ; Mice ; Mice, Transgenic ; Phylogeny ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Rabbits ; Reverse Genetics/methods ; Sequence Alignment ; Sequence Homology, Nucleic Acid ; Sharks ; Signal Transduction ; Swine
Czasopismo naukowe
Tytuł :
Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5.
Autorzy :
Maerker M; University of Hohenheim, Institute of Biology, Department of Zoology, Stuttgart, Germany.
Getwan M; University of Zurich, Institute of Anatomy, Zurich, Switzerland.
Dowdle ME; Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI, USA.
McSheene JC; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
Gonzalez V; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
Pelliccia JL; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
Hamilton DS; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
Yartseva V; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Vejnar C; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Tingler M; University of Hohenheim, Institute of Biology, Department of Zoology, Stuttgart, Germany.
Minegishi K; Laboratory for Organismal Patterning, RIKEN Center for Biosystems Dynamics Research, Hyogo, Japan.
Vick P; University of Hohenheim, Institute of Biology, Department of Zoology, Stuttgart, Germany.
Giraldez AJ; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Hamada H; Laboratory for Organismal Patterning, RIKEN Center for Biosystems Dynamics Research, Hyogo, Japan.
Burdine RD; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
Sheets MD; Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI, USA.
Blum M; University of Hohenheim, Institute of Biology, Department of Zoology, Stuttgart, Germany.
Schweickert A; University of Hohenheim, Institute of Biology, Department of Zoology, Stuttgart, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 16; Vol. 12 (1), pp. 5482. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Body Patterning/*genetics
Intercellular Signaling Peptides and Proteins/*genetics
RNA-Binding Proteins/*genetics
Ribonuclease III/*genetics
Xenopus laevis/*genetics
Zebrafish/*genetics
3' Untranslated Regions/genetics ; Animals ; Embryonic Development/genetics ; Mice ; RNA Stability/genetics ; Xenopus laevis/embryology ; Zebrafish/embryology
Czasopismo naukowe
Tytuł :
Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles.
Autorzy :
Fajner V; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.
Giavazzi F; Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, Università degli Studi di Milano, Segrate, Italy.
Sala S; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.
Oldani A; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.
Martini E; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.
Napoletano F; Laboratorio Nazionale CIB, Area Science Park, Padriciano 99, Trieste, Italy.; Dipartimento di Scienze della Vita, Università degli Studi di Trieste, Trieste, Italy.
Parazzoli D; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.
Cesare G; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, Milan, Italy.
Cerbino R; Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, Università degli Studi di Milano, Segrate, Italy.; Faculty of Physics, University of Vienna, Boltzmanngasse 5, Vienna, Austria.
Maspero E; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. .
Vaccari T; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, Milan, Italy. .
Polo S; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy. .; Dipartimento di Oncologia ed Emato-oncologia, Università degli Studi di Milano, Milan, Italy. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 16; Vol. 12 (1), pp. 5488. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Drosophila Proteins/*genetics
Drosophila melanogaster/*genetics
Neurogenesis/*genetics
Oogenesis/*genetics
Ribonucleoproteins/*genetics
Ubiquitin-Protein Ligases/*genetics
Animals ; Cytoplasmic Granules/metabolism ; Drosophila Proteins/metabolism ; Drosophila melanogaster/cytology ; Drosophila melanogaster/growth & development ; Drosophila melanogaster/metabolism ; Embryo, Nonmammalian ; Fragile X Mental Retardation Protein/genetics ; Fragile X Mental Retardation Protein/metabolism ; Homeostasis/genetics ; Longevity/genetics ; Neurons/cytology ; Neurons/metabolism ; Oocytes/cytology ; Oocytes/metabolism ; Phase Transition ; Profilins/genetics ; Profilins/metabolism ; Protein Biosynthesis ; Protein Processing, Post-Translational ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Ribonucleoproteins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitination
Czasopismo naukowe
Tytuł :
Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes.
Autorzy :
Sugishita H; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Cellular and Molecular Medicine, Advanced Research Departments, Graduate School of Medicine, Chiba University, Chiba, Japan.; International Research Center for Neurointelligence (IRCN), Institutes for Advanced Study, The University of Tokyo, Bunkyo-ku, Japan.
Kondo T; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Ito S; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Nakayama M; Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Kisarazu, Japan.
Yakushiji-Kaminatsui N; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Kawakami E; Artificial Intelligence Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.; Healthcare and Medical Data Driven AI based Predictive Reasoning Development Unit, RIKEN Medical Sciences Innovation Hub Program, Yokohama, Japan.
Koseki Y; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Cellular and Molecular Medicine, Advanced Research Departments, Graduate School of Medicine, Chiba University, Chiba, Japan.
Ohinata Y; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Cellular and Molecular Medicine, Advanced Research Departments, Graduate School of Medicine, Chiba University, Chiba, Japan.
Sharif J; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Harachi M; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Blackledge NP; Department of Biochemistry, University of Oxford, Oxford, UK.
Klose RJ; Department of Biochemistry, University of Oxford, Oxford, UK.
Koseki H; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. .; Cellular and Molecular Medicine, Advanced Research Departments, Graduate School of Medicine, Chiba University, Chiba, Japan. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 09; Vol. 12 (1), pp. 5341. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Embryoid Bodies/*metabolism
Histones/*genetics
Mouse Embryonic Stem Cells/*metabolism
Polycomb Repressive Complex 1/*genetics
Polycomb Repressive Complex 2/*genetics
Animals ; Cell Differentiation ; Embryo, Mammalian ; Embryoid Bodies/cytology ; Histones/metabolism ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; Mice ; Mice, Transgenic ; Mouse Embryonic Stem Cells/cytology ; Platelet-Derived Growth Factor/genetics ; Platelet-Derived Growth Factor/metabolism ; Polycomb Repressive Complex 1/metabolism ; Polycomb Repressive Complex 2/metabolism ; Primary Cell Culture ; SOXC Transcription Factors/genetics ; SOXC Transcription Factors/metabolism ; T-Box Domain Proteins/genetics ; T-Box Domain Proteins/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcription, Genetic ; Ubiquitination
Czasopismo naukowe
Tytuł :
Developmental genetics of color pattern establishment in cats.
Autorzy :
Kaelin CB; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
McGowan KA; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Barsh GS; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA. .; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 07; Vol. 12 (1), pp. 5127. Date of Electronic Publication: 2021 Sep 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Cats/*genetics
Pigmentation/*genetics
Animals ; Animals, Domestic ; Cats/growth & development ; Epidermis/growth & development ; Epidermis/metabolism ; Genotype ; Intercellular Signaling Peptides and Proteins/genetics ; Intercellular Signaling Peptides and Proteins/metabolism ; Keratinocytes/metabolism ; Mutation ; Phenotype ; Single-Cell Analysis ; Skin/anatomy & histology ; Skin/growth & development ; Skin/metabolism ; Wnt Signaling Pathway
Czasopismo naukowe
Tytuł :
Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.
Autorzy :
Linsley JW; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Shah K; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Castello N; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Chan M; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Haddad D; Gladstone Institute of Neurologic Disease, San Francisco, CA, USA.
Doric Z; Gladstone Institute of Neurologic Disease, San Francisco, CA, USA.; Neuroscience Graduate Program, University of California, San Francisco, CA, USA.
Wang S; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Leks W; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Mancini J; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Oza V; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Javaherian A; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA.
Nakamura K; Gladstone Institute of Neurologic Disease, San Francisco, CA, USA.; Biomedical Sciences and Neuroscience Graduate Program, University of California, San Francisco, CA, USA.; Department of Neurology, University of California, San Francisco, CA, USA.
Kokel D; Department of Physiology, University of California, San Francisco, CA, USA.; Institute for Neurodegenerative Disease, University of California, San Francisco, CA, USA.
Finkbeiner S; Gladstone Center for Systems and Therapeutics, San Francisco, CA, USA. .; Taube/Koret Center for Neurodegenerative Disease, Gladstone Institutes, San Francisco, CA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 06; Vol. 12 (1), pp. 5284. Date of Electronic Publication: 2021 Sep 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosensing Techniques*
Gene Expression Regulation, Developmental*
Cell Death/*genetics
Neurodegenerative Diseases/*genetics
Neurons/*metabolism
Animals ; Calcium/metabolism ; Cerebral Cortex/cytology ; Cerebral Cortex/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Disease Models, Animal ; Embryo, Nonmammalian ; Fluorescent Dyes/chemistry ; Genes, Reporter ; Glutamic Acid/pharmacology ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Larva/cytology ; Larva/genetics ; Larva/growth & development ; Larva/metabolism ; Mice ; Mice, Inbred C57BL ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/pathology ; Neurons/cytology ; Neurons/drug effects ; Primary Cell Culture ; Rats ; Rats, Long-Evans ; Single-Cell Analysis/methods ; Superoxide Dismutase-1/genetics ; Superoxide Dismutase-1/metabolism ; Zebrafish/embryology ; Zebrafish/genetics ; Zebrafish/metabolism ; alpha-Synuclein/genetics ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Brain-trait-associated variants impact cell-type-specific gene regulation during neurogenesis.
Autorzy :
Aygün N; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Elwell AL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Liang D; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Lafferty MJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Cheek KE; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Courtney KP; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Mory J; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Hadden-Ford E; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Krupa O; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
de la Torre-Ubieta L; Neurogenetics Program, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Psychiatry and Biobehavioral Sciences, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Geschwind DH; Neurogenetics Program, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Psychiatry and Biobehavioral Sciences, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Love MI; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Stein JL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: .
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Źródło :
American journal of human genetics [Am J Hum Genet] 2021 Sep 02; Vol. 108 (9), pp. 1647-1668. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Quantitative Trait Loci*
Chromosomal Proteins, Non-Histone/*genetics
Neocortex/*metabolism
Neurogenesis/*genetics
Neurons/*metabolism
Alleles ; Alzheimer Disease/diagnosis ; Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Cell Differentiation ; Chromatin/chemistry ; Chromatin/metabolism ; Chromosomal Proteins, Non-Histone/metabolism ; Chromosome Mapping ; Educational Status ; Female ; Fetus ; Genetic Predisposition to Disease ; Genome, Human ; Genome-Wide Association Study ; Humans ; Male ; Neocortex/cytology ; Neocortex/growth & development ; Neural Stem Cells/cytology ; Neural Stem Cells/metabolism ; Neurons/cytology ; Neuroticism ; Parkinson Disease/diagnosis ; Parkinson Disease/genetics ; Parkinson Disease/metabolism ; Primary Cell Culture ; Prognosis ; Schizophrenia/diagnosis ; Schizophrenia/genetics ; Schizophrenia/metabolism ; Transcriptome
Czasopismo naukowe

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