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Wyszukujesz frazę ""Gene Expression Regulation, Neoplastic"" wg kryterium: Temat


Tytuł:
Research progress on the regulatory mechanisms of FOXC1 expression in cancers and its role in drug resistance.
Autorzy:
Yang Y; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Li W; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Yang H; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Zhang Y; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Zhang S; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Xu F; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Hao Y; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Cao W; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Du G; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China.
Wang J; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China. Electronic address: .
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Źródło:
Gene [Gene] 2024 Mar 01; Vol. 897, pp. 148079. Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Triple Negative Breast Neoplasms*/genetics
Drug Resistance, Neoplasm*
Humans ; Cell Line, Tumor ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Receptor tyrosine kinase gene expression profiling of orbital rhabdomyosarcoma unveils MET as a potential biomarker and therapeutic target.
Autorzy:
Chauhan S; Ocular Pathology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, Room No. 725, New Delhi, 110029, India.
Sen S; Ocular Pathology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, Room No. 725, New Delhi, 110029, India. .
Irshad K; Department of Biochemistry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Kashyap S; Ocular Pathology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, Room No. 725, New Delhi, 110029, India.
Pushker N; Ophthalmoplasty Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Meel R; Ophthalmoplasty Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Sharma MC; Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India.
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Źródło:
Human cell [Hum Cell] 2024 Jan; Vol. 37 (1), pp. 297-309. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor Protein-Tyrosine Kinases*/genetics
Receptor Protein-Tyrosine Kinases*/metabolism
Rhabdomyosarcoma, Alveolar*/diagnosis
Rhabdomyosarcoma, Alveolar*/enzymology
Rhabdomyosarcoma, Alveolar*/pathology
Proto-Oncogene Proteins c-met*/genetics
Biomarkers, Tumor*/genetics
Gene Expression Regulation, Neoplastic*
Humans ; Drug Delivery Systems ; Survival Analysis ; Male ; Female ; Infant ; Child, Preschool ; Child ; Adolescent ; Multigene Family/genetics ; Principal Component Analysis ; Gene Expression Profiling
SCR Disease Name:
Rhabdomyosarcoma of the orbit
Czasopismo naukowe
Tytuł:
CPEB2 inhibit cell proliferation through upregulating p21 mRNA stability in glioma.
Autorzy:
Zhao G; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221000, Jiangsu, China.; Department of Emergency Medicine, The First People's Hospital of Kunshan, Kunshan, 215300, Jiangsu, China.
Zhao Z; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Xia M; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Xiao L; Department of Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, China.
Zhu B; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Wang H; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Li X; Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221000, Jiangsu, China. .
Di J; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China. .; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China. .; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 29; Vol. 13 (1), pp. 23103. Date of Electronic Publication: 2023 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
RNA-Binding Proteins*/blood
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Oncogene Protein p21(ras)*/genetics
Oncogene Protein p21(ras)*/metabolism
RNA Stability*/genetics
Glioma*/diagnosis
Glioma*/physiopathology
Gene Expression Regulation, Neoplastic*/genetics
Cell Proliferation/genetics ; Gene Knockdown Techniques ; Apoptosis/genetics ; Cell Cycle Checkpoints/genetics ; Biomarkers, Tumor/blood ; Down-Regulation/genetics ; Cell Line, Tumor ; Mice, Inbred BALB C ; HEK293 Cells ; Humans ; Female ; Animals ; Mice
Czasopismo naukowe
Tytuł:
Comparative analysis of EZH2, p16 and p53 expression in uterine carcinosarcomas.
Autorzy:
Makk E; Department of Pathology, University of Pécs Medical School, Pécs, Hungary.
Bohonyi N; Department of Obstretrics and Gynaecology, University of Pécs Medical School, Pécs, Hungary.
Oszter A; Department of Pathology, University of Pécs Medical School, Pécs, Hungary.
Éles K; Department of Pathology, University of Pécs Medical School, Pécs, Hungary.
Tornóczky T; Department of Pathology, University of Pécs Medical School, Pécs, Hungary.
Tóth A; Department of Medical Imaging, University of Pécs Medical School, Pécs, Hungary.
Kálmán E; Department of Pathology, University of Pécs Medical School, Pécs, Hungary.
Kovács K; Department of Pathology, University of Pécs Medical School, Pécs, Hungary.
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Źródło:
Pathology oncology research : POR [Pathol Oncol Res] 2023 Dec 11; Vol. 29, pp. 1611547. Date of Electronic Publication: 2023 Dec 11 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Uterine Neoplasms*/diagnosis
Uterine Neoplasms*/genetics
Uterine Neoplasms*/physiopathology
Carcinosarcoma*/diagnosis
Carcinosarcoma*/genetics
Carcinosarcoma*/physiopathology
Enhancer of Zeste Homolog 2 Protein*/genetics
Enhancer of Zeste Homolog 2 Protein*/metabolism
Gene Expression Regulation, Neoplastic*
Cyclin-Dependent Kinase Inhibitor p16*/genetics
Cyclin-Dependent Kinase Inhibitor p16*/metabolism
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Humans ; Female ; Middle Aged ; Aged ; Aged, 80 and over ; Gene Expression Profiling ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism
Czasopismo naukowe
Tytuł:
Therapeutic effect of microRNA-21 on differentially expressed hub genes in gastric cancer based on systems biology.
Autorzy:
Kalajahi HG; Department of Molecular Biology and Genetics, Uskudar University, Uskudar, 34662, Istanbul, Turkey.
Yari A; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Amini M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Catal T; Department of Molecular Biology and Genetics, Uskudar University, Uskudar, 34662, Istanbul, Turkey.
Ahmadpour Youshanlui M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Pourbagherian O; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Zhmurov CS; Department of Molecular Biology and Genetics, Uskudar University, Uskudar, 34662, Istanbul, Turkey. .
Mokhtarzadeh A; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 11; Vol. 13 (1), pp. 21906. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Neoplastic*
MicroRNAs*/metabolism
Stomach Neoplasms*/pathology
Humans ; Cell Line, Tumor ; RNA, Messenger/therapeutic use ; Systems Biology
Czasopismo naukowe
Tytuł:
New insights into the regulation of METTL3 and its role in tumors.
Autorzy:
Jin Q; The Key Laboratory of Pathobiology, Ministry of Education, College of Basic Medical Sciences, Jilin University, 126 Xinmin Avenue, Changchun, Jilin, 130021, People's Republic of China.
Qu H; Department of Histology and Embryology, College of Basic Medical Sciences, Jilin University, 126 Xinmin Avenue, Changchun, Jilin, 130021, People's Republic of China. .
Quan C; The Key Laboratory of Pathobiology, Ministry of Education, College of Basic Medical Sciences, Jilin University, 126 Xinmin Avenue, Changchun, Jilin, 130021, People's Republic of China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Nov 23; Vol. 21 (1), pp. 334. Date of Electronic Publication: 2023 Nov 23.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Methyltransferases*/genetics
Gene Expression Regulation, Neoplastic*
RNA
Czasopismo naukowe
Tytuł:
CBX8 promotes lung adenocarcinoma growth and metastasis through transcriptional repression of CDKN2C and SCEL.
Autorzy:
Chen H; Haihe Laboratory of Cell Ecosystem, College of Life Sciences, Nankai University, Tianjin, China.; Department of Biochemistry and Molecular Biology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, Tianjin, China.
Su Y; Department of Biochemistry and Molecular Biology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, Tianjin, China.
Yang L; Department of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Xi L; Department of Biochemistry and Molecular Biology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, Tianjin, China.
Li X; Department of Biochemistry and Molecular Biology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, Tianjin, China.
Lan B; Department of Biochemistry and Molecular Biology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, Tianjin, China.
Liu M; Haihe Laboratory of Cell Ecosystem, College of Life Sciences, Nankai University, Tianjin, China.
Xuan C; Department of Biochemistry and Molecular Biology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, Tianjin, China.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2023 Nov; Vol. 238 (11), pp. 2710-2723. Date of Electronic Publication: 2023 Sep 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/secondary
Gene Expression Regulation, Neoplastic*/genetics
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Polycomb Repressive Complex 1*/genetics
Polycomb Repressive Complex 1*/metabolism
Cyclin-Dependent Kinase Inhibitor p18*/genetics
Carrier Proteins*/genetics
Animals ; Humans ; Mice ; A549 Cells ; Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Polycomb-Group Proteins/genetics ; Polycomb-Group Proteins/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
KIF11 serves as a cell cycle mediator in childhood acute lymphoblastic leukemia.
Autorzy:
Zhu L; Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.; Key Laboratory of Hematology, Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.
Chen C; Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.; Key Laboratory of Hematology, Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.
Kang M; Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.; Key Laboratory of Hematology, Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.
Ma X; Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.; Key Laboratory of Hematology, Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.
Sun X; Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.; Key Laboratory of Hematology, Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.
Xue Y; Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.; Key Laboratory of Hematology, Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China.
Fang Y; Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China. .; Key Laboratory of Hematology, Nanjing Medical University, Nanjing, 220000, Jiangsu Province, China. .
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Źródło:
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2023 Nov; Vol. 149 (17), pp. 15609-15622. Date of Electronic Publication: 2023 Sep 01.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Humans ; Cell Cycle/genetics ; Gene Expression Profiling ; Cell Division ; Gene Regulatory Networks ; Kinesins/genetics
Czasopismo naukowe
Tytuł:
Epigenetic regulation during cancer transitions across 11 tumour types.
Autorzy:
Terekhanova NV; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Karpova A; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Liang WW; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Strzalkowski A; Department of Computer Science, Princeton University, Princeton, NJ, USA.
Chen S; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Li Y; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Southard-Smith AN; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Iglesia MD; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Wendl MC; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Jayasinghe RG; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Liu J; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Song Y; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Cao S; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Houston A; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Liu X; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.
Wyczalkowski MA; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Lu RJ; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Caravan W; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Shinkle A; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.
Naser Al Deen N; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Herndon JM; Department of Surgery, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
Mudd J; Department of Surgery, Washington University in St Louis, St Louis, MO, USA.
Ma C; Department of Computer Science, Princeton University, Princeton, NJ, USA.
Sarkar H; Department of Computer Science, Princeton University, Princeton, NJ, USA.
Sato K; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Ibrahim OM; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Mo CK; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA.
Chasnoff SE; Department of Surgery, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
Porta-Pardo E; Josep Carreras Leukaemia Research Institute, Barcelona, Spain.; Barcelona Supercomputing Center, Barcelona, Spain.
Held JM; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
Pachynski R; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
Schwarz JK; Department of Radiation Oncology, Washington University in St Louis, St Louis, MO, USA.
Gillanders WE; Department of Surgery, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
Kim AH; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.; Department of Neurological Surgery, Washington University in St Louis, St Louis, MO, USA.
Vij R; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
DiPersio JF; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
Puram SV; Department of Otolaryngology-Head & Neck Surgery, Washington University in St Louis, St Louis, MO, USA.
Chheda MG; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
Fuh KC; Department of Obstetrics and Gynecology, University of California, San Francisco, San Francisco, CA, USA.; Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO, USA.
DeNardo DG; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA.
Fields RC; Department of Surgery, Washington University in St Louis, St Louis, MO, USA. .; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA. .
Chen F; Department of Medicine, Washington University in St Louis, St Louis, MO, USA. .; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA. .
Raphael BJ; Department of Computer Science, Princeton University, Princeton, NJ, USA. .
Ding L; Department of Medicine, Washington University in St Louis, St Louis, MO, USA. .; McDonnell Genome Institute, Washington University in St Louis, St Louis, MO, USA. .; Siteman Cancer Center, Washington University in St Louis, St Louis, MO, USA. .; Department of Genetics, Washington University in St Louis, St Louis, MO, USA. .
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Źródło:
Nature [Nature] 2023 Nov; Vol. 623 (7986), pp. 432-441. Date of Electronic Publication: 2023 Nov 01.
Typ publikacji:
Journal Article
MeSH Terms:
Epigenesis, Genetic*/genetics
Gene Expression Regulation, Neoplastic*
Neoplasms*/classification
Neoplasms*/genetics
Neoplasms*/pathology
Humans ; Cell Hypoxia ; Cell Nucleus ; Chromatin/genetics ; Chromatin/metabolism ; Enhancer Elements, Genetic/genetics ; Epithelial-Mesenchymal Transition ; Estrogens/metabolism ; Gene Expression Profiling ; GTPase-Activating Proteins/metabolism ; Neoplasm Metastasis ; Regulatory Sequences, Nucleic Acid/genetics ; Single-Cell Analysis ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
eIF3i promotes colorectal cancer cell survival via augmenting PHGDH translation.
Autorzy:
Zhang Y; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China; Research Laboratory of Cancer Epigenetics and Genomics, Department of General Surgery, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Wan X; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Yang X; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China; Research Laboratory of Cancer Epigenetics and Genomics, Department of General Surgery, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Liu X; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Huang Q; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Zhou L; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Zhang S; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Liu S; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Xiong Q; Research Laboratory of Cancer Epigenetics and Genomics, Department of General Surgery, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Wei M; Research Laboratory of Cancer Epigenetics and Genomics, Department of General Surgery, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Qiu L; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China; Research Laboratory of Cancer Epigenetics and Genomics, Department of General Surgery, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Zhang B; Research Laboratory of Cancer Epigenetics and Genomics, Department of General Surgery, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Han J; Department of Biotherapy, Cancer Center and State Laboratory of Biotherapy, and Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China; Research Laboratory of Cancer Epigenetics and Genomics, Department of General Surgery, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Sep; Vol. 299 (9), pp. 105177. Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/physiopathology
Phosphoglycerate Dehydrogenase*/genetics
Phosphoglycerate Dehydrogenase*/metabolism
Eukaryotic Initiation Factor-3*/genetics
Eukaryotic Initiation Factor-3*/metabolism
Gene Expression Regulation, Neoplastic*/genetics
Humans ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Survival/genetics ; Methyltransferases/metabolism ; RNA, Messenger/metabolism ; Up-Regulation ; Gene Knockdown Techniques ; Animals ; Mice ; Mice, Inbred BALB C ; Female ; Heterografts
Czasopismo naukowe
Tytuł:
m7G-related genes-NCBP2 and EIF4E3 determine immune contexture in head and neck squamous cell carcinoma by regulating CCL4/CCL5 expression.
Autorzy:
Xu X; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China.
Zhao Y; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China.
Ying Y; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China.
Zhu H; Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Luo J; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China.
Mou T; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China.
Zhang Z; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China.
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Źródło:
Molecular carcinogenesis [Mol Carcinog] 2023 Aug; Vol. 62 (8), pp. 1091-1106. Date of Electronic Publication: 2023 Apr 17.
Typ publikacji:
Journal Article
MeSH Terms:
Chemokine CCL5*/genetics
Chemokine CCL5*/metabolism
Head and Neck Neoplasms*/genetics
Head and Neck Neoplasms*/immunology
Head and Neck Neoplasms*/physiopathology
Head and Neck Neoplasms*/therapy
Squamous Cell Carcinoma of Head and Neck*/genetics
Squamous Cell Carcinoma of Head and Neck*/immunology
Squamous Cell Carcinoma of Head and Neck*/physiopathology
Squamous Cell Carcinoma of Head and Neck*/therapy
Chemokine CCL4*/genetics
Chemokine CCL4*/metabolism
Eukaryotic Initiation Factor-4E*/metabolism
Gene Expression Regulation, Neoplastic*/genetics
Humans ; Nuclear Cap-Binding Protein Complex/metabolism ; Cell Line, Tumor ; Male ; Female ; Middle Aged ; Aged ; Immunotherapy ; Models, Statistical ; Mutation/genetics
Czasopismo naukowe
Tytuł:
Rewiring cancer drivers to activate apoptosis.
Autorzy:
Gourisankar S; Department of Pathology, Stanford University, Stanford, CA, USA.; Department of Chemical Engineering, Stanford University, Stanford, CA, USA.
Krokhotin A; Department of Pathology, Stanford University, Stanford, CA, USA.
Ji W; Department of Chemical and Systems Biology, Stanford Cancer Institute, ChEM-H, Stanford University, Stanford, CA, USA.
Liu X; Department of Chemical and Systems Biology, Stanford Cancer Institute, ChEM-H, Stanford University, Stanford, CA, USA.
Chang CY; Department of Pathology, Stanford University, Stanford, CA, USA.
Kim SH; Department of Pathology, Stanford University, Stanford, CA, USA.
Li Z; Department of Chemical and Systems Biology, Stanford Cancer Institute, ChEM-H, Stanford University, Stanford, CA, USA.
Wenderski W; Department of Pathology, Stanford University, Stanford, CA, USA.; Department of Developmental Biology, Stanford University, Stanford, CA, USA.
Simanauskaite JM; Department of Pathology, Stanford University, Stanford, CA, USA.
Yang H; Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Vogel H; Department of Pathology, Stanford University, Stanford, CA, USA.
Zhang T; Department of Chemical and Systems Biology, Stanford Cancer Institute, ChEM-H, Stanford University, Stanford, CA, USA.
Green MR; Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Gray NS; Department of Chemical and Systems Biology, Stanford Cancer Institute, ChEM-H, Stanford University, Stanford, CA, USA. .
Crabtree GR; Department of Pathology, Stanford University, Stanford, CA, USA. .; Department of Developmental Biology, Stanford University, Stanford, CA, USA. .
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Źródło:
Nature [Nature] 2023 Aug; Vol. 620 (7973), pp. 417-425. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Apoptosis*/genetics
Gene Expression Regulation, Neoplastic*/drug effects
Lymphoma, Large B-Cell, Diffuse*/drug therapy
Lymphoma, Large B-Cell, Diffuse*/genetics
Lymphoma, Large B-Cell, Diffuse*/metabolism
Lymphoma, Large B-Cell, Diffuse*/pathology
Transcription Factors*/metabolism
Humans ; Cell Cycle Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-6/genetics ; Proto-Oncogene Proteins c-bcl-6/metabolism ; Epigenesis, Genetic/drug effects ; Promoter Regions, Genetic ; Carcinogenesis/drug effects ; Carcinogenesis/genetics
Czasopismo naukowe
Tytuł:
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Autorzy:
Zhong B; Department of Hepatobiliary and Pancreatic Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Zhu Q; Department of Respiratory and Critical Care Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Wang L; Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Wang F; Department of Hepatobiliary and Pancreatic Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Zheng Y; Department of Hepatobiliary and Pancreatic Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Lin S; Department of Hepatobiliary and Pancreatic Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Cheng X; Department of Hepatobiliary and Pancreatic Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
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Źródło:
Cell biology international [Cell Biol Int] 2023 Aug; Vol. 47 (8), pp. 1368-1380. Date of Electronic Publication: 2023 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplastic Stem Cells*/metabolism
Gene Expression Regulation, Neoplastic*
Humans ; Cell Line, Tumor ; Cell Survival ; Proliferating Cell Nuclear Antigen/metabolism ; Cell Movement ; Ubiquitination ; Cell Proliferation ; Ubiquitin Thiolesterase/genetics ; Ubiquitin Thiolesterase/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
An antioxidant response element regulates the HIF1α axis in breast cancer cells.
Autorzy:
Lacher SE; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, 55812, USA. Electronic address: .
Skon-Hegg C; Whiteside Institute for Clinical Research, St. Luke's Hospital, University of Minnesota Medical School, Duluth, MN, 55812, USA.
Ruis BL; Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.
Krznarich J; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, 55812, USA.
Slattery M; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, 55812, USA. Electronic address: .
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Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2023 Aug 01; Vol. 204, pp. 243-251. Date of Electronic Publication: 2023 May 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidant Response Elements*
Hypoxia-Inducible Factor 1, alpha Subunit*/genetics
Gene Expression Regulation, Neoplastic*
Humans ; Cell Line, Tumor ; Mutation ; NF-E2-Related Factor 2/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/metabolism
Czasopismo naukowe
Tytuł:
Heritable transcriptional defects from aberrations of nuclear architecture.
Autorzy:
Papathanasiou S; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. .; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. .; Institute of Molecular Biology, Mainz, Germany. .
Mynhier NA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Liu S; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
Brunette G; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Stokasimov E; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Jacob E; Single-Cell Sequencing Program, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.; AstraZeneca, Waltham, MA, USA.
Li L; Single-Cell Sequencing Program, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biomedical Informatics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Comenho C; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
van Steensel B; Division of Gene Regulation and Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Buenrostro JD; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Zhang CZ; Single-Cell Sequencing Program, Dana-Farber Cancer Institute, Boston, MA, USA. cheng-zhong_.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA. cheng-zhong_.; Department of Biomedical Informatics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. cheng-zhong_.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. cheng-zhong_.
Pellman D; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. david_.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. david_.; Single-Cell Sequencing Program, Dana-Farber Cancer Institute, Boston, MA, USA. david_.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. david_.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. david_.
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Źródło:
Nature [Nature] 2023 Jul; Vol. 619 (7968), pp. 184-192. Date of Electronic Publication: 2023 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Chromosomal Instability*
Epigenesis, Genetic*
Gene Expression Regulation, Neoplastic*
Micronuclei, Chromosome-Defective*
Neoplasms*/genetics
Neoplasms*/pathology
Transcription, Genetic*
Humans ; Chromatin/genetics ; Chromatin/metabolism ; Chromosomes/genetics ; Clone Cells/metabolism ; DNA Damage/genetics ; Single-Cell Gene Expression Analysis
Czasopismo naukowe
Tytuł:
Papillary Thyroid Carcinoma: A thorough Bioinformatic Analysis of Gene Expression and Clinical Data.
Autorzy:
Petrini I; Department of Computer Science and Engineering, Universidad Nacional del Sur, Bahía Blanca 8000, Argentina.
Cecchini RL; Department of Computer Science and Engineering, Universidad Nacional del Sur, Bahía Blanca 8000, Argentina.; Institute for Computer Science and Engineering (UNS-CONICET), Bahía Blanca 8000, Argentina.
Mascaró M; Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur, Bahía Blanca 8000, Argentina.
Ponzoni I; Department of Computer Science and Engineering, Universidad Nacional del Sur, Bahía Blanca 8000, Argentina.; Institute for Computer Science and Engineering (UNS-CONICET), Bahía Blanca 8000, Argentina.
Carballido JA; Department of Computer Science and Engineering, Universidad Nacional del Sur, Bahía Blanca 8000, Argentina.; Institute for Computer Science and Engineering (UNS-CONICET), Bahía Blanca 8000, Argentina.
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Źródło:
Genes [Genes (Basel)] 2023 Jun 11; Vol. 14 (6). Date of Electronic Publication: 2023 Jun 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Thyroid Neoplasms*/pathology
Humans ; Thyroid Cancer, Papillary/metabolism ; Neoplasm Recurrence, Local/genetics ; Computational Biology ; Gene Expression
Czasopismo naukowe
Tytuł:
Identification of a novel gene signature for neuroblastoma differentiation using a Boolean implication network.
Autorzy:
Zage PE; Department of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, California, USA.
Huo Y; Department of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, California, USA.
Subramonian D; Department of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, California, USA.
Le Clorennec C; Department of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, California, USA.
Ghosh P; Department of Medicine, University of California San Diego, La Jolla, California, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA.; Veterans Affairs Medical Center, La Jolla, California, USA.
Sahoo D; Department of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, California, USA.; Department of Computer Science and Engineering, Jacobs School of Engineering, University of California San Diego, La Jolla, California, USA.
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Źródło:
Genes, chromosomes & cancer [Genes Chromosomes Cancer] 2023 Jun; Vol. 62 (6), pp. 313-331. Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Neuroblastoma*/pathology
Humans ; N-Myc Proto-Oncogene Protein/genetics ; N-Myc Proto-Oncogene Protein/metabolism ; N-Myc Proto-Oncogene Protein/therapeutic use ; Cell Line, Tumor ; Cell Differentiation/genetics ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł:
Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours.
Autorzy:
Gavish A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Tyler M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Greenwald AC; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Hoefflin R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Simkin D; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Tschernichovsky R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.; Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel.
Galili Darnell N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Somech E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Barbolin C; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Antman T; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Kovarsky D; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Barrett T; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St Louis, MO, USA.; Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.
Gonzalez Castro LN; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.
Halder D; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Chanoch-Myers R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Laffy J; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Mints M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.; Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden.
Wider A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Tal R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Spitzer A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Hara T; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Raitses-Gurevich M; The Oncology Institute, Chaim Sheba Medical Center, Ramat Gan, Israel.
Stossel C; The Oncology Institute, Chaim Sheba Medical Center, Ramat Gan, Israel.; The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Golan T; The Oncology Institute, Chaim Sheba Medical Center, Ramat Gan, Israel.; The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tirosh A; The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.; Division of Endocrinology, Diabetes and Metabolism, Chaim Sheba Medical Center, Ramat Gan, Israel.
Suvà ML; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Puram SV; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St Louis, MO, USA.; Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA.
Tirosh I; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. .
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Źródło:
Nature [Nature] 2023 Jun; Vol. 618 (7965), pp. 598-606. Date of Electronic Publication: 2023 May 31.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Genetic Heterogeneity*
Neoplasms*/classification
Neoplasms*/genetics
Neoplasms*/pathology
Single-Cell Gene Expression Analysis*
Humans ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
LncRNA-PVT1 was identified as a key regulator for TMZ resistance and STAT-related pathway in glioma.
Autorzy:
Chen Y; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China.
Ma F; Department of Intensive Care Unit, The Third People's Hospital of Zhengzhou, Zhengzhou, China.
Zhang Z; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China.
Guo Y; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China.
Shen H; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China.
Chen H; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China. .
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Źródło:
BMC cancer [BMC Cancer] 2023 May 18; Vol. 23 (1), pp. 455. Date of Electronic Publication: 2023 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Temozolomide*/pharmacology
Temozolomide*/therapeutic use
Drug Resistance, Neoplasm*/genetics
Gene Expression Regulation, Neoplastic*/genetics
Glioma*/drug therapy
Glioma*/genetics
Glioma*/physiopathology
Gene Knockdown Techniques ; Carcinogenesis/genetics ; Survival Analysis ; STAT Transcription Factors/metabolism ; Janus Kinases/metabolism ; Cell Line, Tumor ; Humans ; Male ; Female ; Adult ; Middle Aged ; Biomarkers, Tumor/metabolism
Czasopismo naukowe
Tytuł:
N6-methyladenosine-modified CircPSMA7 enhances bladder cancer malignancy through the miR-128-3p/MAPK1 axis.
Autorzy:
Yi J; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Ma X; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Ying Y; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Liu Z; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Tang Y; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Shu X; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Sun J; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Wu Y; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Lu D; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Wang X; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Luo J; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Liu B; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Zheng X; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China.
Lin Y; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China. Electronic address: .
Li J; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China. Electronic address: .
Xie L; Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Cancer Center, Zhejiang University, Hangzhou, 310058 China. Electronic address: .
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Źródło:
Cancer letters [Cancer Lett] 2024 Mar 31; Vol. 585, pp. 216613. Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
Urinary Bladder Neoplasms*/pathology
Humans ; RNA, Circular/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Cell Movement/genetics ; Methyltransferases/metabolism ; Mitogen-Activated Protein Kinase 1/metabolism
Czasopismo naukowe

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