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Wyszukujesz frazę ""Gene Expression Regulation, Viral"" wg kryterium: Temat


Tytuł :
The critical region for viral RNA encapsidation in leader promoter of Nipah virus.
Autorzy :
Pong LY; Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Selangor Darul Ehsan, Malaysia.; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor Darul Ehsan, Malaysia.
Rabu A; Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Selangor Darul Ehsan, Malaysia.
Ibrahim N; Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Selangor Darul Ehsan, Malaysia. .
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Źródło :
Molecular genetics and genomics : MGG [Mol Genet Genomics] 2020 Nov; Vol. 295 (6), pp. 1501-1516. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Viral*
Promoter Regions, Genetic*
RNA, Viral*/physiology
Virus Assembly*
Nipah Virus/*genetics
5' Untranslated Regions ; Cell Line ; Mutagenesis ; Nucleocapsid Proteins/genetics ; RNA, Messenger ; Recombinant Proteins/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
The epigenetic implication in coronavirus infection and therapy.
Autorzy :
Atlante S; Laboratorio di Epigenetica, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri 4, 27100, Pavia, Italy.
Mongelli A; Laboratorio di Epigenetica, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri 4, 27100, Pavia, Italy.
Barbi V; Laboratorio di Epigenetica, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri 4, 27100, Pavia, Italy.
Martelli F; Laboratorio di Cardiologia Molecolare, Policlinico San Donato IRCCS, Milan, Italy.
Farsetti A; Institute for Systems Analysis and Computer Science 'A. Ruberti' (IASI), National Research Council (CNR), Rome, Italy. .
Gaetano C; Laboratorio di Epigenetica, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri 4, 27100, Pavia, Italy. .
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Źródło :
Clinical epigenetics [Clin Epigenetics] 2020 Oct 21; Vol. 12 (1), pp. 156. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Epigenesis, Genetic*
Gene Expression Regulation, Viral*/drug effects
Antiviral Agents/*pharmacology
Betacoronavirus/*physiology
Coronavirus Infections/*drug therapy
Coronavirus Infections/*genetics
Pneumonia, Viral/*drug therapy
Pneumonia, Viral/*genetics
Coronavirus Infections/immunology ; Cytokines/genetics ; Cytokines/immunology ; Host-Pathogen Interactions ; Humans ; Inflammation/immunology ; Pandemics ; Pneumonia, Viral/immunology ; RNA Processing, Post-Transcriptional
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Unfolding SARS-CoV-2 viral genome to understand its gene expression regulation.
Autorzy :
Dinka H; Department of Applied Biology, School of Applied Natural Science, Adama Science and Technology University, P.O.Box 1888, Adama, Ethiopia. Electronic address: .
Milkesa A; Department of Applied Biology, School of Applied Natural Science, Adama Science and Technology University, P.O.Box 1888, Adama, Ethiopia.
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Źródło :
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2020 Oct; Vol. 84, pp. 104386. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Viral*
Genome, Viral*
Transcription Initiation Site*
Betacoronavirus/*genetics
Transcription Factors/*genetics
Viral Proteins/*genetics
Amino Acid Sequence ; Betacoronavirus/metabolism ; Binding Sites ; Computational Biology/methods ; Coronavirus Infections/virology ; CpG Islands ; Humans ; Nucleotide Motifs ; Open Reading Frames ; Pandemics ; Pneumonia, Viral/virology ; Promoter Regions, Genetic ; Protein Binding ; Transcription Factors/metabolism ; Viral Proteins/metabolism
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latency.
Autorzy :
Krasnopolsky S; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Kuzmina A; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Taube R; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Sep 21; Vol. 16 (9), pp. e1008834. Date of Electronic Publication: 2020 Sep 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*
Gene Silencing*
Repressor Proteins*/genetics
Repressor Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Transcription, Genetic*
Virus Latency*
CD4-Positive T-Lymphocytes/*metabolism
HIV-1/*physiology
CD4-Positive T-Lymphocytes/virology ; CRISPR-Cas Systems ; Gene Knockout Techniques ; Genome-Wide Association Study ; Humans ; Jurkat Cells ; Promoter Regions, Genetic ; Tripartite Motif-Containing Protein 28/genetics ; Tripartite Motif-Containing Protein 28/metabolism
Czasopismo naukowe
Tytuł :
The molecular virology of coronaviruses.
Autorzy :
Hartenian E; Department of Molecular and Cell Biology, University of California, Berkeley, California, USA.
Nandakumar D; Department of Plant and Microbial Biology, University of California, Berkeley, California, USA.
Lari A; Department of Plant and Microbial Biology, University of California, Berkeley, California, USA.
Ly M; Department of Molecular and Cell Biology, University of California, Berkeley, California, USA.
Tucker JM; Department of Plant and Microbial Biology, University of California, Berkeley, California, USA.
Glaunsinger BA; Department of Molecular and Cell Biology, University of California, Berkeley, California, USA .; Department of Plant and Microbial Biology, University of California, Berkeley, California, USA.; Howard Hughes Medical Institute, University of California, Berkeley, California, USA.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Sep 11; Vol. 295 (37), pp. 12910-12934. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Gene Expression Regulation, Viral*
Virus Physiological Phenomena*
Coronavirus/*physiology
Coronavirus Infections/*virology
Animals ; Antigens, Viral/immunology ; Coronavirus/genetics ; Coronavirus/immunology ; Coronavirus Infections/genetics ; Coronavirus Infections/immunology ; Host-Pathogen Interactions ; Humans
Czasopismo naukowe
Tytuł :
Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene.
Autorzy :
Lin YT; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Chiweshe S; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
McCormick D; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Raper A; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Wickenhagen A; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.
DeFillipis V; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.
Gaunt E; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Simmonds P; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Wilson SJ; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.
Grey F; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Sep 04; Vol. 16 (9), pp. e1008844. Date of Electronic Publication: 2020 Sep 04 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
CpG Islands*
Gene Expression Regulation, Viral*
Virus Replication*
Cytomegalovirus/*physiology
Cytomegalovirus Infections/*metabolism
RNA-Binding Proteins/*metabolism
Repressor Proteins/*metabolism
Cell Line ; Cytomegalovirus Infections/genetics ; Cytomegalovirus Infections/pathology ; Humans ; Immediate-Early Proteins ; RNA-Binding Proteins/genetics ; Repressor Proteins/genetics ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Tripartite Motif Proteins/genetics ; Tripartite Motif Proteins/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
Profiling of immune related genes silenced in EBV-positive gastric carcinoma identified novel restriction factors of human gammaherpesviruses.
Autorzy :
Fiches GN; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Zhou D; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Kong W; Gladstone Institute of Virology and Immunology, University of California, San Francisco, California, United States of America.
Biswas A; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Ahmed EH; Division of Hematology, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Baiocchi RA; Division of Hematology, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Zhu J; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Santoso N; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Aug 25; Vol. 16 (8), pp. e1008778. Date of Electronic Publication: 2020 Aug 25 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Epigenesis, Genetic*
Gene Expression Regulation, Viral*
Host-Pathogen Interactions*
Biomarkers/*metabolism
Gammaherpesvirinae/*isolation & purification
Herpesviridae Infections/*complications
Stomach Neoplasms/*genetics
Biomarkers/analysis ; DNA Methylation ; Gammaherpesvirinae/genetics ; HEK293 Cells ; Herpesviridae Infections/virology ; Homeobox A10 Proteins/genetics ; Humans ; Incidence ; Metallothionein/genetics ; Stomach Neoplasms/epidemiology ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/virology ; Virus Activation ; Virus Replication
Czasopismo naukowe
Tytuł :
The chromatin landscape at the HIV-1 provirus integration site determines viral expression.
Autorzy :
Vansant G; Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Flanders, Belgium.
Chen HC; Center for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Catalunya, Spain.
Zorita E; Center for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Catalunya, Spain.
Trejbalová K; Institute of Molecular Genetics, Czech Academy of Sciences, Videnska, Prague, Czech Republic.
Miklík D; Institute of Molecular Genetics, Czech Academy of Sciences, Videnska, Prague, Czech Republic.
Filion G; Center for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Catalunya, Spain.; University Pompeu Fabra, Barcelona, Catalunya, Spain.
Debyser Z; Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Flanders, Belgium.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Aug 20; Vol. 48 (14), pp. 7801-7817.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*/drug effects
Gene Silencing*
Virus Integration*/drug effects
HIV-1/*genetics
Proviruses/*genetics
Cell Line ; Chromatin/metabolism ; HIV Integrase Inhibitors/pharmacology ; HIV-1/drug effects ; HIV-1/metabolism ; Histones/metabolism ; Humans ; Intercellular Signaling Peptides and Proteins ; RNA, Viral/metabolism
Czasopismo naukowe
Tytuł :
SARS-CoV-2 infection risk assessment in the endometrium: viral infection-related gene expression across the menstrual cycle.
Autorzy :
Henarejos-Castillo I; Department of Genomic and Systems Reproductive Medicine, IVI-RMA IVI Foundation, Valencia, Spain; Instituto de Investigación Sanitaria Hospital Universitario y Politécnico La Fe, Valencia, Spain; Department of Pediatrics, Obstetrics and Gynaecology, University of Valencia, Valencia, Spain.
Sebastian-Leon P; Department of Genomic and Systems Reproductive Medicine, IVI-RMA IVI Foundation, Valencia, Spain; Instituto de Investigación Sanitaria Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Devesa-Peiro A; Department of Genomic and Systems Reproductive Medicine, IVI-RMA IVI Foundation, Valencia, Spain; Instituto de Investigación Sanitaria Hospital Universitario y Politécnico La Fe, Valencia, Spain; Department of Pediatrics, Obstetrics and Gynaecology, University of Valencia, Valencia, Spain.
Pellicer A; Department of Genomic and Systems Reproductive Medicine, IVI-RMA IVI Foundation, Valencia, Spain; Instituto de Investigación Sanitaria Hospital Universitario y Politécnico La Fe, Valencia, Spain; Department of Pediatrics, Obstetrics and Gynaecology, University of Valencia, Valencia, Spain.
Diaz-Gimeno P; Department of Genomic and Systems Reproductive Medicine, IVI-RMA IVI Foundation, Valencia, Spain; Instituto de Investigación Sanitaria Hospital Universitario y Politécnico La Fe, Valencia, Spain. Electronic address: .
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Źródło :
Fertility and sterility [Fertil Steril] 2020 Aug; Vol. 114 (2), pp. 223-232. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Viral*
Betacoronavirus/*metabolism
Coronavirus Infections/*metabolism
Endometrium/*metabolism
Endometrium/*virology
Pneumonia, Viral/*metabolism
Adult ; Age Factors ; Betacoronavirus/genetics ; Coronavirus Infections/genetics ; Female ; Humans ; Menstrual Cycle ; Middle Aged ; Pandemics ; Peptidyl-Dipeptidase A/biosynthesis ; Peptidyl-Dipeptidase A/genetics ; Pneumonia, Viral/genetics ; Risk Assessment/methods ; Virus Internalization ; Young Adult
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Major Capsid Protein Synthesis from the Genomic RNA of Feline Calicivirus.
Autorzy :
Urban C; Institut für Immunologie, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Luttermann C; Institut für Immunologie, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany .
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Źródło :
Journal of virology [J Virol] 2020 Jul 16; Vol. 94 (15). Date of Electronic Publication: 2020 Jul 16 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Viral*
Genome, Viral*
Protein Biosynthesis*
Calicivirus, Feline/*metabolism
Capsid Proteins/*biosynthesis
RNA, Viral/*metabolism
Animals ; Calicivirus, Feline/genetics ; Capsid Proteins/genetics ; Cats ; Cell Line ; Cricetinae ; RNA, Viral/genetics
Czasopismo naukowe
Tytuł :
The RNA quality control pathway nonsense-mediated mRNA decay targets cellular and viral RNAs to restrict KSHV.
Autorzy :
Zhao Y; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232-2363, USA.
Ye X; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232-2363, USA.
Shehata M; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232-2363, USA.
Dunker W; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232-2363, USA.
Xie Z; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232-2363, USA.
Karijolich J; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232-2363, USA. .; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232-2363, USA. .; Vanderbilt-Ingram Cancer Center, Nashville, TN, 37232-2363, USA. .; Vanderbilt Institute for Infection, Immunology and Inflammation, Nashville, TN, 37232-2363, USA. .; Vanderbilt Center for Immunobiology, Nashville, TN, 37232-2363, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jul 03; Vol. 11 (1), pp. 3345. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*
Nonsense Mediated mRNA Decay*
Herpesvirus 8, Human/*genetics
RNA, Viral/*metabolism
Virus Activation/*genetics
Cell Line, Tumor ; HEK293 Cells ; Herpesvirus 8, Human/metabolism ; Herpesvirus 8, Human/pathogenicity ; Host-Pathogen Interactions/genetics ; Humans ; Immediate-Early Proteins/genetics ; Immediate-Early Proteins/metabolism ; Lymphoma, Primary Effusion/genetics ; Lymphoma, Primary Effusion/virology ; RNA, Messenger/metabolism ; RNA-Seq ; Sarcoma, Kaposi/genetics ; Sarcoma, Kaposi/virology ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Transcriptional Activation ; Unfolded Protein Response/genetics ; Virus Latency/genetics
Czasopismo naukowe
Tytuł :
An essential N-terminal serine-rich motif in the AAV VP1 and VP2 subunits that may play a role in viral transcription.
Autorzy :
Robinson TM; Department of Chemistry, Rice University, United States.
Ho ML; Department of Bioengineering, Rice University, United States.
Wahlig B; Department of Bioengineering, Rice University, United States.
Gough V; Department of Bioengineering, Rice University, United States.
Banta A; Department of Bioengineering, Rice University, United States.
Reyes Gamas K; Department of Bioengineering, Rice University, United States.
Kang B; Department of Bioengineering, Rice University, United States.
Lee E; Department of Bioengineering, Rice University, United States.
Chen W; Department of Chemical and Biomolecular Engineering, Rice University, United States.
Suh J; Department of Bioengineering, Rice University, United States. Electronic address: .
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Źródło :
Virology [Virology] 2020 Jul; Vol. 546, pp. 127-132. Date of Electronic Publication: 2020 Apr 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Expression Regulation, Viral*
Capsid Proteins/*chemistry
Capsid Proteins/*metabolism
Dependovirus/*genetics
Amino Acid Motifs ; Capsid Proteins/genetics ; Dependovirus/chemistry ; Dependovirus/physiology ; Genetic Vectors/chemistry ; Genetic Vectors/genetics ; Genetic Vectors/physiology ; Humans ; Virus Assembly ; Virus Replication
Czasopismo naukowe
Tytuł :
Aminopeptidase N Expression, Not Interferon Responses, Determines the Intestinal Segmental Tropism of Porcine Deltacoronavirus.
Autorzy :
Yin L; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Chen J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Li L; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Guo S; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Xue M; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Zhang J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Liu X; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Feng L; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China .
Liu P; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China .
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Źródło :
Journal of virology [J Virol] 2020 Jul 01; Vol. 94 (14). Date of Electronic Publication: 2020 Jul 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*
Host-Pathogen Interactions*
Viral Tropism*
CD13 Antigens/*genetics
Coronavirus/*physiology
Coronavirus Infections/*veterinary
Swine Diseases/*metabolism
Swine Diseases/*virology
Animals ; Enterocolitis/metabolism ; Enterocolitis/pathology ; Enterocolitis/virology ; Interferons/metabolism ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Intestinal Mucosa/virology ; Swine ; Swine Diseases/pathology ; Virus Replication
Czasopismo naukowe
Tytuł :
Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription.
Autorzy :
Ivanov A; Center for Sickle Cell Disease, Howard University, 2201 Georgia Ave., N.W., Suite 321D, Washington, D.C., 20059, USA.
Ramanathan P; Department of Pathology, University of Texas, Medical Branch at Galveston, 301 University Boulevard, Galveston, TX, 77574-0609, USA.
Parry C; Center for Sickle Cell Disease, Howard University, 2201 Georgia Ave., N.W., Suite 321D, Washington, D.C., 20059, USA.; Department of Microbiology, Howard University, Washington, D.C., 20059, USA.
Ilinykh PA; Department of Pathology, University of Texas, Medical Branch at Galveston, 301 University Boulevard, Galveston, TX, 77574-0609, USA.
Lin X; Center for Sickle Cell Disease, Howard University, 2201 Georgia Ave., N.W., Suite 321D, Washington, D.C., 20059, USA.; College of Dentistry, Howard University, Washington, D.C., 20059, USA.
Petukhov M; Division of Molecular and Radiation Biophysics, Russian Nuclear Physics Institute Named After B. P. Konstantinov, National Research Center 'Kurchatov Institute', Gatchina, 188300, Russia.; Russian Scientific Center of Radiology and Surgical Technologies Named After A. M. Granov, St. Petersburg, 197758, Russia.
Obukhov Y; Center for Sickle Cell Disease, Howard University, 2201 Georgia Ave., N.W., Suite 321D, Washington, D.C., 20059, USA.
Ammosova T; Center for Sickle Cell Disease, Howard University, 2201 Georgia Ave., N.W., Suite 321D, Washington, D.C., 20059, USA.; Department of Medicine, Howard University, Washington, D.C., 20059, USA.
Amarasinghe GK; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, 63110, USA.
Bukreyev A; Department of Pathology, University of Texas, Medical Branch at Galveston, 301 University Boulevard, Galveston, TX, 77574-0609, USA. .; Department of Microbiology and Immunology, University of Texas, Medical Branch at Galveston, 301 University Boulevard, Galveston, TX, 77574-0609, USA. .; Galveston National Laboratory, University of Texas, Medical Branch at Galveston, 301 University Boulevard, Galveston, TX, 77574-0609, USA. .
Nekhai S; Center for Sickle Cell Disease, Howard University, 2201 Georgia Ave., N.W., Suite 321D, Washington, D.C., 20059, USA. .; Department of Microbiology, Howard University, Washington, D.C., 20059, USA. .; Department of Medicine, Howard University, Washington, D.C., 20059, USA. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Jul; Vol. 77 (13), pp. 2579-2603. Date of Electronic Publication: 2019 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Viral*
Transcription, Genetic*
Ebolavirus/*genetics
Ebolavirus/*metabolism
Nucleoproteins/*metabolism
Viral Core Proteins/*metabolism
Animals ; Chiroptera ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Nucleoproteins/chemistry ; Phosphorylation ; Proteomics ; Ribonucleoproteins/metabolism ; Vero Cells ; Viral Core Proteins/chemistry ; Viral Envelope Proteins/chemistry ; Viral Envelope Proteins/metabolism ; Viral Matrix Proteins/chemistry ; Viral Matrix Proteins/metabolism ; Viral Proteins/chemistry ; Viral Proteins/metabolism ; Virion/genetics ; Virion/metabolism
Czasopismo naukowe
Tytuł :
High-throughput sequencing analysis of a "hit and run" cell and animal model of KSHV tumorigenesis.
Autorzy :
Naipauer J; Tumor Biology Program, Sylvester Comprehensive Cancer Center and Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; UM-CFAR/ Sylvester CCC Argentina Consortium for Research and Training in Virally induced AIDS-Malignancies University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Salyakina D; Tumor Biology Program, Sylvester Comprehensive Cancer Center and Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Journo G; Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Rosario S; Tumor Biology Program, Sylvester Comprehensive Cancer Center and Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Williams S; UM-CFAR/ Sylvester CCC Argentina Consortium for Research and Training in Virally induced AIDS-Malignancies University of Miami Miller School of Medicine, Miami, Florida, United States of America.; Neurology Basic Science Division, Sylvester Comprehensive Cancer Center; University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Abba M; UM-CFAR/ Sylvester CCC Argentina Consortium for Research and Training in Virally induced AIDS-Malignancies University of Miami Miller School of Medicine, Miami, Florida, United States of America.; Centro de Investigaciones Inmunológicas Básicas y Aplicadas, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina.
Shamay M; Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Mesri EA; Tumor Biology Program, Sylvester Comprehensive Cancer Center and Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; UM-CFAR/ Sylvester CCC Argentina Consortium for Research and Training in Virally induced AIDS-Malignancies University of Miami Miller School of Medicine, Miami, Florida, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Jun 30; Vol. 16 (6), pp. e1008589. Date of Electronic Publication: 2020 Jun 30 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Transformation, Viral*
DNA Methylation*
Gene Expression Regulation, Neoplastic*
Gene Expression Regulation, Viral*
Herpesvirus 8, Human*/genetics
Herpesvirus 8, Human*/metabolism
Neoplasms, Experimental*/genetics
Neoplasms, Experimental*/metabolism
Neoplasms, Experimental*/pathology
Neoplasms, Experimental*/virology
Plasmids*/genetics
Plasmids*/metabolism
Sarcoma, Kaposi*/genetics
Sarcoma, Kaposi*/metabolism
Sarcoma, Kaposi*/pathology
Sarcoma, Kaposi*/virology
Animals ; Cell Line ; High-Throughput Nucleotide Sequencing ; Mice
Czasopismo naukowe
Tytuł :
Various miRNAs compensate the role of miR-122 on HCV replication.
Autorzy :
Ono C; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Fukuhara T; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Li S; Department of Genome Informatics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Wang J; Department of Pharmacology, Penn State University College of Medicine, Hershey, Pennsylvania, United States of America.
Sato A; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Izumi T; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Fauzyah Y; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Yamamoto T; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Morioka Y; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Dokholyan NV; Department of Pharmacology, Penn State University College of Medicine, Hershey, Pennsylvania, United States of America.; Department of Biochemistry & Molecular Biology, Penn State University College of Medicine, Hershey, Pennsylvania, United States of America.
Standley DM; Department of Genome Informatics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Matsuura Y; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Jun 23; Vol. 16 (6), pp. e1008308. Date of Electronic Publication: 2020 Jun 23 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*
Protein Biosynthesis*
RNA, Viral*/biosynthesis
RNA, Viral*/genetics
Hepacivirus/*physiology
MicroRNAs/*metabolism
Viral Proteins/*biosynthesis
Virus Replication/*physiology
5' Untranslated Regions ; Cell Line, Tumor ; Humans ; MicroRNAs/genetics ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
Dynamic and scalable DNA-based information storage.
Autorzy :
Lin KN; Department of Chemical and Biomolecular Engineering, North Carolina State University, Campus Box 7905, Raleigh, NC, 27695-7905, USA.
Volkel K; Department of Electrical and Computer Engineering, North Carolina State University, Campus Box 7911, Raleigh, NC, 27695-7911, USA.
Tuck JM; Department of Electrical and Computer Engineering, North Carolina State University, Campus Box 7911, Raleigh, NC, 27695-7911, USA. .
Keung AJ; Department of Chemical and Biomolecular Engineering, North Carolina State University, Campus Box 7905, Raleigh, NC, 27695-7905, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 12; Vol. 11 (1), pp. 2981. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Regulation, Viral*
Genetic Code*
Bacteriophage T7/*genetics
DNA/*genetics
Promoter Regions, Genetic/*genetics
Algorithms ; DNA, Single-Stranded/genetics ; Models, Genetic ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Determination of RNA structural diversity and its role in HIV-1 RNA splicing.
Autorzy :
Tomezsko PJ; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Program in Virology, Harvard Medical School, Boston, MA, USA.; Brigham and Women's Hospital, Boston, MA, USA.
Corbin VDA; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria, Australia.
Gupta P; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
Swaminathan H; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
Glasgow M; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Massachusetts Institute of Technology, Cambridge, MA, USA.
Persad S; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Massachusetts Institute of Technology, Cambridge, MA, USA.
Edwards MD; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.
Mcintosh L; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Victoria, Australia.; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Mathematics and Statistics, University of Melbourne, Melbourne, Victoria, Australia.
Papenfuss AT; Bioinformatics Division, Walter and Eliza Hall Institute, Parkville, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria, Australia.; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Department of Mathematics and Statistics, University of Melbourne, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.
Emery A; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Swanstrom R; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Zang T; Laboratory of Retrovirology, The Rockefeller University, New York, NY, USA.
Lan TCT; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
Bieniasz P; Laboratory of Retrovirology, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Kuritzkes DR; Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Tsibris A; Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Rouskin S; Whitehead Institute for Biomedical Research, Cambridge, MA, USA. .
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Źródło :
Nature [Nature] 2020 Jun; Vol. 582 (7812), pp. 438-442. Date of Electronic Publication: 2020 May 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*
Mutation*
Alternative Splicing/*genetics
HIV-1/*genetics
RNA Splice Sites/*genetics
RNA, Viral/*chemistry
RNA, Viral/*genetics
Algorithms ; Base Sequence ; HEK293 Cells ; Humans ; Nucleic Acid Conformation ; RNA Folding ; Reproducibility of Results ; Sequence Analysis, RNA ; Sulfuric Acid Esters ; Thermodynamics
Czasopismo naukowe
Tytuł :
Structural basis for transcriptional start site control of HIV-1 RNA fate.
Autorzy :
Brown JD; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Kharytonchyk S; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109-5620, USA.
Chaudry I; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Iyer AS; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Carter H; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Becker G; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Desai Y; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Glang L; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Choi SH; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Singh K; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Lopresti MW; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Orellana M; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Rodriguez T; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Oboh U; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Hijji J; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Ghinger FG; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Stewart K; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Francis D; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Edwards B; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Chen P; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Case DA; Department of Chemistry and Chemical Biology and BioMaPS Institute, Rutgers University, 610 Taylor Road, Piscataway, NJ 08854-8087, USA.
Telesnitsky A; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109-5620, USA. .
Summers MF; Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA. .
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Źródło :
Science (New York, N.Y.) [Science] 2020 Apr 24; Vol. 368 (6489), pp. 413-417.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Base Pairing*
Gene Expression Regulation, Viral*
Transcription Initiation Site*
HIV-1/*genetics
RNA Caps/*genetics
RNA, Viral/*genetics
5' Untranslated Regions/genetics ; Base Composition ; Eukaryotic Initiation Factor-4E/metabolism ; Guanosine/chemistry ; Humans ; Nuclear Magnetic Resonance, Biomolecular ; Protein Biosynthesis ; RNA Caps/chemistry ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
Zika virus infection differentially affects genome-wide transcription in neuronal cells and myeloid dendritic cells.
Autorzy :
Park T; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea.; Department of Human and Environmental Toxicology, University of Science and Technology, Daejeon, Republic of Korea.
Kang MG; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Baek SH; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea.; Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Lee CH; Bio and Drug Discovery Division, Center for Information-Based Drug Research, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Park D; Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea.; Department of Human and Environmental Toxicology, University of Science and Technology, Daejeon, Republic of Korea.; Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
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Źródło :
PloS one [PLoS One] 2020 Apr 14; Vol. 15 (4), pp. e0231049. Date of Electronic Publication: 2020 Apr 14 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*
Zika Virus*
Dendritic Cells/*virology
Myeloid Cells/*virology
Neurons/*virology
Zika Virus Infection/*metabolism
Dendritic Cells/metabolism ; Humans ; Myeloid Cells/metabolism ; Neurons/metabolism ; Transcription, Genetic
Czasopismo naukowe

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