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Tytuł:
Human microRNA hsa-miR-15b-5p targets the RNA template component of the RNA-dependent RNA polymerase structure in severe acute respiratory syndrome coronavirus 2.
Autorzy:
Sato A; Department of Biochemistry and Molecular Biology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan.
Ogino Y; Department of Gene Regulation, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan.
Tanuma SI; Department of Genomic Medicinal Science, Research Institute for Science and Technology, Organization for Research Advancement, Tokyo University of Science, Noda, Japan.
Uchiumi F; Department of Gene Regulation, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan.
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Źródło:
Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2021; Vol. 40 (8), pp. 790-797. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Viral*
COVID-19/*metabolism
MicroRNAs/*physiology
RNA-Dependent RNA Polymerase/*metabolism
Biomarkers/metabolism ; COVID-19/enzymology ; COVID-19/genetics ; COVID-19/virology ; Databases, Genetic ; Humans ; In Vitro Techniques ; SARS-CoV-2 ; Transcription, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Studies on the gene regulation involved in the lytic-lysogenic switch in Staphylococcus aureus temperate bacteriophage Phi11.
Autorzy:
Das A; Department of Biological Sciences, BITS Pilani K K Birla Goa Campus, NH17B, Zuarinagar, Goa 403726, India.
Mandal S; Department of Biochemistry, Bose Institute, Kolkata 700054, India.
Hemmadi V; Department of Biological Sciences, BITS Pilani K K Birla Goa Campus, NH17B, Zuarinagar, Goa 403726, India.
Ratre V; Department of Biological Sciences, BITS Pilani K K Birla Goa Campus, NH17B, Zuarinagar, Goa 403726, India.
Biswas M; Department of Biological Sciences, BITS Pilani K K Birla Goa Campus, NH17B, Zuarinagar, Goa 403726, India.
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Źródło:
Journal of biochemistry [J Biochem] 2020 Dec 26; Vol. 168 (6), pp. 659-668.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Viral*
Virus Replication*
Lysogeny/*genetics
Staphylococcus Phages/*genetics
Staphylococcus Phages/*growth & development
Staphylococcus aureus/*virology
Viral Proteins/*metabolism
Base Sequence ; Operator Regions, Genetic ; Protein Binding ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Viral Proteins/genetics ; Virus Integration
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
"Non-Essential" Proteins of HSV-1 with Essential Roles In Vivo: A Comprehensive Review.
Autorzy:
Dogrammatzis C; Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Waisner H; Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Kalamvoki M; Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
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Źródło:
Viruses [Viruses] 2020 Dec 23; Vol. 13 (1). Date of Electronic Publication: 2020 Dec 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Gene Expression Regulation, Viral*
Host-Pathogen Interactions*/genetics
Host-Pathogen Interactions*/immunology
Virus Replication*
Herpes Simplex/*virology
Herpesvirus 1, Human/*physiology
Viral Proteins/*genetics
Viral Proteins/*metabolism
Animals ; Endonucleases/genetics ; Endonucleases/metabolism ; Gene Silencing ; Herpes Simplex/immunology ; Herpes Simplex/metabolism ; Humans ; Nucleic Acids/metabolism ; Phosphotransferases/genetics ; Phosphotransferases/metabolism ; Trans-Activators ; Viral Regulatory and Accessory Proteins/genetics ; Viral Regulatory and Accessory Proteins/metabolism ; Virulence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Significantly Improved Recovery of Recombinant Sonchus Yellow Net Rhabdovirus by Expressing the Negative-Strand Genomic RNA.
Autorzy:
Ma X; State Key Laboratory of Rice Biology, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.
Li Z; State Key Laboratory of Rice Biology, Institute of Biotechnology, Zhejiang University, Hangzhou 310058, China.; Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang University, Hangzhou 310058, China.; Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, Zhejiang University, Hangzhou 310058, China.
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Źródło:
Viruses [Viruses] 2020 Dec 17; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Viral*
Genetic Engineering*
Genome, Viral*
RNA, Viral*
Rhabdoviridae/*genetics
Genes, Reporter ; Plant Diseases/genetics ; Plant Diseases/virology ; Plant Viruses/genetics ; RNA Interference ; Sonchus/virology ; Transcription, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of Serum and Gene Expression of Galectin-4, Interleukin-27, and Complement-7 in Hepatitis C Virus-Infected Egyptian Patients.
Autorzy:
Abdel-Tawab MS; Medical Biochemistry Department, Faculty of Medicine, Beni-Suef University, Egypt.
Fouad HH; Medical Biochemistry Department, Faculty of Medicine, Cairo University, Egypt.
Omran DA; Endemic Medicine and Hepatology Department, Faculty of Medicine, Cairo University, Egypt.
Abdou AE; Microbiology and Immunology Department, Faculty of Medicine, Al-Azhar University, Egypt.
Zaied SM; Clinical and Chemical Pathology Department, Faculty of Medicine, Beni-Suef University, Egypt.
Mohamed AA; Medical Biochemistry Department, Faculty of Medicine, Beni-Suef University, Egypt.; Medical Biochemistry Division, Pathology Department, Faculty of Medicine, Jouf University, Sakaka, Saudi Arabia.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Dec 15; Vol. 2020, pp. 8879758. Date of Electronic Publication: 2020 Dec 15 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Viral*
Complement C7/*immunology
Galectin 4/*blood
Hepatitis C, Chronic/*blood
Interleukins/*blood
Case-Control Studies ; Cytokines/metabolism ; Egypt ; Gene Expression Profiling ; Hepacivirus ; Hepatitis C, Chronic/virology ; Humans ; Immune System ; Immunotherapy ; Inflammation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Small Interfering RNAs Are Highly Effective Inhibitors of Crimean-Congo Hemorrhagic Fever Virus Replication In Vitro.
Autorzy:
Földes F; National Laboratory of Virology, BSL-4 Laboratory, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, 7622 Pécs, Hungary.
Madai M; National Laboratory of Virology, BSL-4 Laboratory, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, 7622 Pécs, Hungary.
Papp H; National Laboratory of Virology, BSL-4 Laboratory, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, 7622 Pécs, Hungary.
Kemenesi G; National Laboratory of Virology, BSL-4 Laboratory, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, 7622 Pécs, Hungary.
Zana B; National Laboratory of Virology, BSL-4 Laboratory, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, 7622 Pécs, Hungary.
Geiger L; Department of Laboratory Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Gombos K; Department of Laboratory Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Somogyi B; National Laboratory of Virology, BSL-4 Laboratory, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Bock-Marquette I; Regenerative Science, Sport and Medicina Research Group, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Jakab F; National Laboratory of Virology, BSL-4 Laboratory, Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.; Institute of Biology, Faculty of Sciences, University of Pécs, 7622 Pécs, Hungary.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Dec 07; Vol. 25 (23). Date of Electronic Publication: 2020 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Viral*
RNA Interference*
Virus Replication*
Hemorrhagic Fever Virus, Crimean-Congo/*physiology
RNA, Small Interfering/*genetics
Cell Line ; Cells, Cultured ; Cytopathogenic Effect, Viral ; Dose-Response Relationship, Drug ; Humans ; RNA, Small Interfering/administration & dosage ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Advances in the Bioinformatics Knowledge of mRNA Polyadenylation in Baculovirus Genes.
Autorzy:
Peros IG; Laboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Invertebrados, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Cerrudo CS; Laboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Invertebrados, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Pilloff MG; Laboratorio de Virus Emergentes, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Belaich MN; Laboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Invertebrados, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Lozano ME; Laboratorio de Virus Emergentes, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Ghiringhelli PD; Laboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Invertebrados, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
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Źródło:
Viruses [Viruses] 2020 Dec 06; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Gene Expression Regulation, Viral*
Polyadenylation*
Transcription, Genetic*
Baculoviridae/*genetics
Insect Viruses/*genetics
RNA, Messenger/*genetics
3' Untranslated Regions ; Animals ; Baculoviridae/metabolism ; Binding Sites ; Genome, Viral ; Genomics/methods ; Protein Binding ; RNA Processing, Post-Transcriptional ; Regulatory Sequences, Ribonucleic Acid ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Depicting HIV-1 Transcriptional Mechanisms: A Summary of What We Know.
Autorzy:
Dutilleul A; Service of Molecular Virology, Department of Molecular Virology (DBM), Université Libre de Bruxelles (ULB), 6041 Gosselies, Belgium.
Rodari A; Service of Molecular Virology, Department of Molecular Virology (DBM), Université Libre de Bruxelles (ULB), 6041 Gosselies, Belgium.
Van Lint C; Service of Molecular Virology, Department of Molecular Virology (DBM), Université Libre de Bruxelles (ULB), 6041 Gosselies, Belgium.
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Źródło:
Viruses [Viruses] 2020 Dec 03; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Gene Expression Regulation, Viral*
RNA, Viral*
Transcription, Genetic*
HIV Infections/*virology
HIV-1/*physiology
CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD4-Positive T-Lymphocytes/virology ; HIV Infections/immunology ; Host-Pathogen Interactions ; Humans ; Virus Activation ; Virus Latency
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Crosstalk of Epigenetics and Metabolism in Herpesvirus Infection.
Autorzy:
Pei Y; Departments of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, and the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Robertson ES; Departments of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, and the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
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Źródło:
Viruses [Viruses] 2020 Dec 01; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Energy Metabolism*
Epigenesis, Genetic*
Gene Expression Regulation, Viral*
Herpesviridae/*physiology
Herpesviridae Infections/*genetics
Herpesviridae Infections/*metabolism
Herpesviridae Infections/*virology
Host-Pathogen Interactions/*genetics
Acetyl Coenzyme A/metabolism ; DNA Methylation ; Fatty Acids/metabolism ; Flavin-Adenine Dinucleotide/metabolism ; Glutamates/metabolism ; Glycolysis ; Histones/metabolism ; Humans ; NAD
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The DDX23 Negatively Regulates Translation and Replication of Foot-and-Mouth Disease Virus and Is Degraded by 3C Proteinase.
Autorzy:
Abdullah SW; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Han S; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Wu J; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Zhang Y; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Bai M; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Jin Y; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Zhi X; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Guan J; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Sun S; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Guo H; State Key Laboratory of Veterinary Etiological Biology, O.I.E./China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
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Źródło:
Viruses [Viruses] 2020 Nov 25; Vol. 12 (12). Date of Electronic Publication: 2020 Nov 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Viral*
Virus Replication*
Cysteine Endopeptidases/*metabolism
DEAD-box RNA Helicases/*metabolism
Foot-and-Mouth Disease/*metabolism
Foot-and-Mouth Disease/*virology
Foot-and-Mouth Disease Virus/*physiology
Viral Proteins/*metabolism
3C Viral Proteases ; Animals ; Cell Line ; DEAD-box RNA Helicases/chemistry ; DEAD-box RNA Helicases/genetics ; Internal Ribosome Entry Sites ; Lysosomes ; Protein Binding ; Protein Biosynthesis ; Proteolysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The epigenetic implication in coronavirus infection and therapy.
Autorzy:
Atlante S; Laboratorio di Epigenetica, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri 4, 27100, Pavia, Italy.
Mongelli A; Laboratorio di Epigenetica, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri 4, 27100, Pavia, Italy.
Barbi V; Laboratorio di Epigenetica, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri 4, 27100, Pavia, Italy.
Martelli F; Laboratorio di Cardiologia Molecolare, Policlinico San Donato IRCCS, Milan, Italy.
Farsetti A; Institute for Systems Analysis and Computer Science 'A. Ruberti' (IASI), National Research Council (CNR), Rome, Italy. .
Gaetano C; Laboratorio di Epigenetica, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri 4, 27100, Pavia, Italy. .
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Źródło:
Clinical epigenetics [Clin Epigenetics] 2020 Oct 21; Vol. 12 (1), pp. 156. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Epigenesis, Genetic*
Gene Expression Regulation, Viral*/drug effects
Antiviral Agents/*pharmacology
Betacoronavirus/*physiology
Coronavirus Infections/*drug therapy
Coronavirus Infections/*genetics
Pneumonia, Viral/*drug therapy
Pneumonia, Viral/*genetics
COVID-19 ; Coronavirus Infections/immunology ; Cytokines/genetics ; Cytokines/immunology ; Host-Pathogen Interactions ; Humans ; Inflammation/immunology ; Pandemics ; Pneumonia, Viral/immunology ; RNA Processing, Post-Transcriptional ; SARS-CoV-2
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of Viral Ribonucleoproteins in Human Papillomavirus Type 16 Gene Expression.
Autorzy:
Kajitani N; Department of Laboratory Medicine, Lund University, 22184 Lund, Sweden.
Schwartz S; Department of Laboratory Medicine, Lund University, 22184 Lund, Sweden.
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Źródło:
Viruses [Viruses] 2020 Sep 30; Vol. 12 (10). Date of Electronic Publication: 2020 Sep 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Gene Expression Regulation, Viral*
Alphapapillomavirus/*genetics
Alphapapillomavirus/*metabolism
Papillomavirus Infections/*virology
Ribonucleoproteins/*metabolism
Alternative Splicing ; Human papillomavirus 16/genetics ; Humans ; Polyadenylation ; RNA Splicing ; RNA, Messenger ; Ribonucleoproteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Regulation of Expression and Latency in BLV and HTLV.
Autorzy:
Pluta A; Department of Biochemistry, National Veterinary Research Institute, 24-100 Puławy, Poland.
Jaworski JP; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Instituto de Virología, Nicolás Repetto y De los Reseros (s/n), CP1686 Hurlingham, Buenos Aires, Argentina.
Douville RN; Department of Biology, The University of Winnipeg, Winnipeg, MB R3B 2E9, Canada.; Department of Immunology, University of Manitoba, Winnipeg, MB R3E 0T5, Canada.
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Źródło:
Viruses [Viruses] 2020 Sep 25; Vol. 12 (10). Date of Electronic Publication: 2020 Sep 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Gene Expression Regulation, Viral*
Human T-lymphotropic virus 1/*genetics
Leukemia Virus, Bovine/*genetics
Virus Latency/*genetics
Animals ; Enhancer Elements, Genetic/genetics ; Epigenesis, Genetic ; Human T-lymphotropic virus 1/physiology ; Humans ; Leukemia Virus, Bovine/physiology ; Mutation ; RNA, Untranslated/metabolism ; Terminal Repeat Sequences/genetics ; Viral Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latency.
Autorzy:
Krasnopolsky S; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Kuzmina A; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Taube R; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
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Źródło:
PLoS pathogens [PLoS Pathog] 2020 Sep 21; Vol. 16 (9), pp. e1008834. Date of Electronic Publication: 2020 Sep 21 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Viral*
Gene Silencing*
Repressor Proteins*/genetics
Repressor Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Transcription, Genetic*
Virus Latency*
CD4-Positive T-Lymphocytes/*metabolism
HIV-1/*physiology
CD4-Positive T-Lymphocytes/virology ; CRISPR-Cas Systems ; Gene Knockout Techniques ; Genome-Wide Association Study ; Humans ; Jurkat Cells ; Promoter Regions, Genetic ; Tripartite Motif-Containing Protein 28/genetics ; Tripartite Motif-Containing Protein 28/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene.
Autorzy:
Lin YT; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Chiweshe S; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
McCormick D; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Raper A; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Wickenhagen A; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.
DeFillipis V; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.
Gaunt E; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Simmonds P; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Wilson SJ; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.
Grey F; Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
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Źródło:
PLoS pathogens [PLoS Pathog] 2020 Sep 04; Vol. 16 (9), pp. e1008844. Date of Electronic Publication: 2020 Sep 04 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alternative Splicing*
CpG Islands*
Gene Expression Regulation, Viral*
Virus Replication*
Cytomegalovirus/*physiology
Cytomegalovirus Infections/*metabolism
RNA-Binding Proteins/*metabolism
Repressor Proteins/*metabolism
Cell Line ; Cytomegalovirus Infections/genetics ; Cytomegalovirus Infections/pathology ; Humans ; Immediate-Early Proteins ; RNA-Binding Proteins/genetics ; Repressor Proteins/genetics ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Tripartite Motif Proteins/genetics ; Tripartite Motif Proteins/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Profiling of immune related genes silenced in EBV-positive gastric carcinoma identified novel restriction factors of human gammaherpesviruses.
Autorzy:
Fiches GN; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Zhou D; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Kong W; Gladstone Institute of Virology and Immunology, University of California, San Francisco, California, United States of America.
Biswas A; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Ahmed EH; Division of Hematology, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Baiocchi RA; Division of Hematology, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Zhu J; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
Santoso N; Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2020 Aug 25; Vol. 16 (8), pp. e1008778. Date of Electronic Publication: 2020 Aug 25 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Epigenesis, Genetic*
Gene Expression Regulation, Viral*
Host-Pathogen Interactions*
Biomarkers/*metabolism
Gammaherpesvirinae/*isolation & purification
Herpesviridae Infections/*complications
Stomach Neoplasms/*genetics
Biomarkers/analysis ; DNA Methylation ; Gammaherpesvirinae/genetics ; HEK293 Cells ; Herpesviridae Infections/virology ; Homeobox A10 Proteins/genetics ; Humans ; Incidence ; Metallothionein/genetics ; Stomach Neoplasms/epidemiology ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/virology ; Virus Activation ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel transcription regulatory sequences and factors of the immune evasion protein ICP47 (US12) of herpes simplex viruses.
Autorzy:
Cheng JT; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China.
Wang YY; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China.
Zhu LZ; Department of Interventional Therapy, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute. 52, Fucheng Road, Haidian District, Beijing, 100142, China.
Zhang Y; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China.
Cai WQ; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China.
Han ZW; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China.
Zhou Y; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China.
Wang XW; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Laboratory Medicine, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.
Peng XC; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Pathophysiology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China.
Xiang Y; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China.
Yang HY; Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Cui SZ; State Key Laboratory of Respiratory Disease, Affiliated Cancer Hospital Institute of Guangzhou Medical University, Guangzhou, 510095, China.
Ma Z; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China. .; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China. .
Liu BR; Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. .
Xin HW; Laboratory of Oncology, School of Basic Medicine, Health Science Center, Yangtze University, 1 Nanhuan Road, Jingzhou, 434023, Hubei, China. hongwu_.; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Health Science Center, Yangtze University, Jingzhou, 434023, Hubei, China. hongwu_.; Lianjiang People's Hospital, Guangdong, 524400, China. hongwu_.
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Źródło:
Virology journal [Virol J] 2020 Jul 10; Vol. 17 (1), pp. 101. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Viral*
Immune Evasion*
Transcription, Genetic*
Herpesvirus 1, Human/*genetics
Immediate-Early Proteins/*genetics
China ; Herpes Simplex/virology ; Herpesvirus 1, Human/classification ; Humans ; Male ; Phylogeny ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent IFNB1 Expression.
Autorzy:
Schwanke H; Institute of Genetics, Technische Universität Braunschweig, 38106 Braunschweig, Germany.; Viral Immune Modulation Research Group, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Stempel M; Institute of Genetics, Technische Universität Braunschweig, 38106 Braunschweig, Germany.; Viral Immune Modulation Research Group, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Brinkmann MM; Institute of Genetics, Technische Universität Braunschweig, 38106 Braunschweig, Germany.; Viral Immune Modulation Research Group, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
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Źródło:
Viruses [Viruses] 2020 Jul 07; Vol. 12 (7). Date of Electronic Publication: 2020 Jul 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Gene Expression Regulation, Viral*
Host-Pathogen Interactions*
Interferon Regulatory Factor-3/*metabolism
Humans ; Interferon-beta
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High-throughput sequencing analysis of a "hit and run" cell and animal model of KSHV tumorigenesis.
Autorzy:
Naipauer J; Tumor Biology Program, Sylvester Comprehensive Cancer Center and Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; UM-CFAR/ Sylvester CCC Argentina Consortium for Research and Training in Virally induced AIDS-Malignancies University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Salyakina D; Tumor Biology Program, Sylvester Comprehensive Cancer Center and Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Journo G; Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Rosario S; Tumor Biology Program, Sylvester Comprehensive Cancer Center and Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Williams S; UM-CFAR/ Sylvester CCC Argentina Consortium for Research and Training in Virally induced AIDS-Malignancies University of Miami Miller School of Medicine, Miami, Florida, United States of America.; Neurology Basic Science Division, Sylvester Comprehensive Cancer Center; University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Abba M; UM-CFAR/ Sylvester CCC Argentina Consortium for Research and Training in Virally induced AIDS-Malignancies University of Miami Miller School of Medicine, Miami, Florida, United States of America.; Centro de Investigaciones Inmunológicas Básicas y Aplicadas, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina.
Shamay M; Daniella Lee Casper Laboratory in Viral Oncology, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Mesri EA; Tumor Biology Program, Sylvester Comprehensive Cancer Center and Miami Center for AIDS Research, Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.; UM-CFAR/ Sylvester CCC Argentina Consortium for Research and Training in Virally induced AIDS-Malignancies University of Miami Miller School of Medicine, Miami, Florida, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2020 Jun 30; Vol. 16 (6), pp. e1008589. Date of Electronic Publication: 2020 Jun 30 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Transformation, Viral*
DNA Methylation*
Gene Expression Regulation, Neoplastic*
Gene Expression Regulation, Viral*
Herpesvirus 8, Human*/genetics
Herpesvirus 8, Human*/metabolism
Neoplasms, Experimental*/genetics
Neoplasms, Experimental*/metabolism
Neoplasms, Experimental*/pathology
Neoplasms, Experimental*/virology
Plasmids*/genetics
Plasmids*/metabolism
Sarcoma, Kaposi*/genetics
Sarcoma, Kaposi*/metabolism
Sarcoma, Kaposi*/pathology
Sarcoma, Kaposi*/virology
Animals ; Cell Line ; High-Throughput Nucleotide Sequencing ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Various miRNAs compensate the role of miR-122 on HCV replication.
Autorzy:
Ono C; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Fukuhara T; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Li S; Department of Genome Informatics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Wang J; Department of Pharmacology, Penn State University College of Medicine, Hershey, Pennsylvania, United States of America.
Sato A; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Izumi T; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Fauzyah Y; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Yamamoto T; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Morioka Y; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Dokholyan NV; Department of Pharmacology, Penn State University College of Medicine, Hershey, Pennsylvania, United States of America.; Department of Biochemistry & Molecular Biology, Penn State University College of Medicine, Hershey, Pennsylvania, United States of America.
Standley DM; Department of Genome Informatics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Matsuura Y; Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
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Źródło:
PLoS pathogens [PLoS Pathog] 2020 Jun 23; Vol. 16 (6), pp. e1008308. Date of Electronic Publication: 2020 Jun 23 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Viral*
Protein Biosynthesis*
RNA, Viral*/biosynthesis
RNA, Viral*/genetics
Hepacivirus/*physiology
MicroRNAs/*metabolism
Viral Proteins/*biosynthesis
Virus Replication/*physiology
5' Untranslated Regions ; Cell Line, Tumor ; Humans ; MicroRNAs/genetics ; Viral Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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