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Tytuł :
Mucoepidermoid carcinoma of the salivary glands revisited with special reference to histologic grading and CRTC1/3-MAML2 genotyping.
Autorzy :
Fehr A; Sahlgrenska Center for Cancer Research, Department of Pathology, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden. .
Werenicz S; Department of Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Trocchi P; Institute of Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany.
Falk M; Institute for Hematopathology, Hamburg, Germany.
Friedrich RE; Department of Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Stammler A; Faculty of Medicine, Justus-Liebig-University Giessen, Giessen, Germany.
Stang A; Institute of Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany.; Cancer Registry North Rhine-Westphalia, Bochum, Germany.
Oesterling F; Cancer Registry North Rhine-Westphalia, Bochum, Germany.
Khil L; Cancer Registry North Rhine-Westphalia, Bochum, Germany.
Stenman G; Sahlgrenska Center for Cancer Research, Department of Pathology, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
Böcker W; Gerhard Seifert Reference-Center - Hansepathnet, Hamburg, Germany.
Tiemann K; Institute for Hematopathology, Hamburg, Germany.
Löning T; Gerhard Seifert Reference-Center - Hansepathnet, Hamburg, Germany.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Nov; Vol. 479 (5), pp. 975-985. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study
MeSH Terms :
Gene Fusion*
Biomarkers, Tumor/*genetics
Carcinoma, Mucoepidermoid/*genetics
Carcinoma, Mucoepidermoid/*pathology
Salivary Gland Neoplasms/*genetics
Salivary Gland Neoplasms/*pathology
Trans-Activators/*genetics
Transcription Factors/*genetics
Adolescent ; Adult ; Carcinoma, Mucoepidermoid/mortality ; Carcinoma, Mucoepidermoid/therapy ; Female ; Germany ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; Predictive Value of Tests ; Progression-Free Survival ; Registries ; Salivary Gland Neoplasms/mortality ; Salivary Gland Neoplasms/therapy ; Time Factors ; Young Adult
Czasopismo naukowe
Tytuł :
FOXO1 gene involvement in a non-rhabdomyosarcomatous neoplasm.
Autorzy :
Haefliger S; Institute of Medical Genetics and Pathology, University Hospital of Basel, University of Basel, Schönbeinstrasse 40, CH-4031, Basel, Switzerland.
Genevay M; Institute of Pathology Dianapath, Geneva, Switzerland.
Bihl M; Institute of Medical Genetics and Pathology, University Hospital of Basel, University of Basel, Schönbeinstrasse 40, CH-4031, Basel, Switzerland.
Marone R; Department of Biomedicine, University Hospital of Basel, University of Basel, Basel, Switzerland.
Baumhoer D; Institute of Medical Genetics and Pathology, University Hospital of Basel, University of Basel, Schönbeinstrasse 40, CH-4031, Basel, Switzerland.; Bone Tumor Reference Center at the Institute of Medical Genetics and Pathology, University Hospital of Basel, University of Basel, Basel, Switzerland.
Papaloizos M; Center for Hand Surgery and Therapy, Geneva, Switzerland.
Matter MS; Institute of Medical Genetics and Pathology, University Hospital of Basel, University of Basel, Schönbeinstrasse 40, CH-4031, Basel, Switzerland. .
Bode-Lesniewska B; Institute of Pathology Enge, Zürich, Switzerland.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Nov; Vol. 479 (5), pp. 1031-1036. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Case Reports
MeSH Terms :
Gene Fusion*
Biomarkers, Tumor/*genetics
Forkhead Box Protein O1/*genetics
Myoepithelioma/*genetics
N-Acetylglucosaminyltransferases/*genetics
Soft Tissue Neoplasms/*genetics
Biomarkers, Tumor/analysis ; Female ; Forearm ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Middle Aged ; Myoepithelioma/chemistry ; Myoepithelioma/pathology ; Myoepithelioma/surgery ; Soft Tissue Neoplasms/chemistry ; Soft Tissue Neoplasms/pathology ; Soft Tissue Neoplasms/surgery ; Treatment Outcome
Raport
Tytuł :
Factors Impacting Clinically Relevant RNA Fusion Assays Using Next-Generation Sequencing.
Autorzy :
Ramani NS; From the Department of Pathology (Ramani, Broaddus, Chen, Rashid, Lazar, Roy-Chowdhuri), The University of Texas MD Anderson Cancer Center, Houston.
Patel KP; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Routbort MJ; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Alvarez H; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Broaddus R; From the Department of Pathology (Ramani, Broaddus, Chen, Rashid, Lazar, Roy-Chowdhuri), The University of Texas MD Anderson Cancer Center, Houston.
Chen H; From the Department of Pathology (Ramani, Broaddus, Chen, Rashid, Lazar, Roy-Chowdhuri), The University of Texas MD Anderson Cancer Center, Houston.
Rashid A; From the Department of Pathology (Ramani, Broaddus, Chen, Rashid, Lazar, Roy-Chowdhuri), The University of Texas MD Anderson Cancer Center, Houston.
Lazar A; From the Department of Pathology (Ramani, Broaddus, Chen, Rashid, Lazar, Roy-Chowdhuri), The University of Texas MD Anderson Cancer Center, Houston.
Lucas FAS; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Yao H; Department of Bioinformatics and Computational Biology (Yao), The University of Texas MD Anderson Cancer Center, Houston. Broaddus is currently with the Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill.
Manekia J; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Dang H; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Barkoh BA; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Medeiros LJ; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Luthra R; Department of Hematopathology (Patel, Routbort, Alvarez, San Lucas, Manekia, Dang, Barkoh, Medeiros, Luthra), The University of Texas MD Anderson Cancer Center, Houston.
Roy-Chowdhuri S; From the Department of Pathology (Ramani, Broaddus, Chen, Rashid, Lazar, Roy-Chowdhuri), The University of Texas MD Anderson Cancer Center, Houston.
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Źródło :
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2021 Nov 01; Vol. 145 (11), pp. 1405-1412.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gene Fusion*
High-Throughput Nucleotide Sequencing*
Sequence Analysis, RNA*
Transcriptome*
Biomarkers, Tumor/*genetics
Neoplasms/*genetics
RNA, Neoplasm/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biopsy ; Child ; Databases, Factual ; Female ; Humans ; Male ; Middle Aged ; Neoplasms/pathology ; Predictive Value of Tests ; Reproducibility of Results ; Retrospective Studies ; Young Adult
Czasopismo naukowe
Tytuł :
Recurrent YAP1-TFE3 Gene Fusions in Clear Cell Stromal Tumor of the Lung.
Autorzy :
Agaimy A; Institute of Pathology, Friedrich Alexander University Erlangen-Nürnberg, University Hospital, Erlangen.
Stoehr R; Institute of Pathology, Friedrich Alexander University Erlangen-Nürnberg, University Hospital, Erlangen.
Michal M; Department of Pathology, Charles University, Faculty of Medicine in Plzen.; Bioptical Laboratory Ltd, Plzen, Czech Republic.
Christopoulos P; Department of Thoracic Oncology, Thoraxklinik, National Center for Tumor Diseases at Heidelberg University Hospital.; Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL).
Winter H; Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL).; Department of Thoracic Surgery, Thoraxklinik, Heidelberg University Hospital.
Zhang L; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY.
Stenzinger A; Institute of Pathology, University of Heidelberg, Heidelberg, Germany.
Michal M; Department of Pathology, Charles University, Faculty of Medicine in Plzen.; Bioptical Laboratory Ltd, Plzen, Czech Republic.
Mechtersheimer G; Institute of Pathology, University of Heidelberg, Heidelberg, Germany.
Antonescu CR; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 Nov 01; Vol. 45 (11), pp. 1541-1549.
Typ publikacji :
Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Fusion*
Adaptor Proteins, Signal Transducing/*genetics
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*genetics
Biomarkers, Tumor/*genetics
Hemangioblastoma/*genetics
Lung Neoplasms/*genetics
Solitary Pulmonary Nodule/*genetics
Transcription Factors/*genetics
Adult ; Aged ; Female ; Genetic Predisposition to Disease ; Hemangioblastoma/secondary ; Hemangioblastoma/surgery ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Middle Aged ; Phenotype ; Pneumonectomy ; Solitary Pulmonary Nodule/pathology ; Solitary Pulmonary Nodule/surgery ; Treatment Outcome
Czasopismo naukowe
Tytuł :
A Novel NIPBL-NACC1 Gene Fusion Is Characteristic of the Cholangioblastic Variant of Intrahepatic Cholangiocarcinoma.
Autorzy :
Argani P; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Palsgrove DN; Department of Pathology.
Anders RA; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Smith SC; Department of Pathology, Virginia Commonwealth University, Richmond, VI.
Saoud C; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Kwon R; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Voltaggio L; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Assarzadegan N; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Oshima K; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Rooper L; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Matoso A; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD.
Zhang L; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.
Cantarel BL; Bioinformatics Core Facility, Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX.
Gagan J; Department of Pathology.
Antonescu CR; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 Nov 01; Vol. 45 (11), pp. 1550-1560.
Typ publikacji :
Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Fusion*
Bile Duct Neoplasms/*genetics
Biomarkers, Tumor/*genetics
Cell Cycle Proteins/*genetics
Cholangiocarcinoma/*genetics
Neoplasm Proteins/*genetics
Repressor Proteins/*genetics
Bile Duct Neoplasms/pathology ; Bile Duct Neoplasms/surgery ; Cholangiocarcinoma/pathology ; Cholangiocarcinoma/surgery ; Female ; Genetic Predisposition to Disease ; Hepatectomy ; Humans ; Male ; Middle Aged ; Phenotype ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Pan-TRK Immunohistochemistry Is Highly Correlated With NTRK3 Gene Rearrangements in Salivary Gland Tumors.
Autorzy :
Csanyi-Bastien M; Department of Pathology, Centre Henri Becquerel.
Lanic MD; INSERM 1245, Rouen Normandy Uniiversity.
Beaussire L; Department of Pathology, Centre Henri Becquerel.
Ferric S; Department of Pathology, Centre Henri Becquerel.
François A; Department of Pathology, Rouen University Hospital, Rouen.
Meseure D; Platform of Experimental Pathology, Department of Diagnostic and Theranostic Medicine, Curie Institute.
Jardin F; INSERM 1245, Rouen Normandy Uniiversity.
Wassef M; Department of Pathology, Lariboisière Hospital, Paris, France.
Ruminy P; INSERM 1245, Rouen Normandy Uniiversity.
Laé M; Department of Pathology, Centre Henri Becquerel.; INSERM 1245, Rouen Normandy Uniiversity.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 Nov 01; Vol. 45 (11), pp. 1487-1498.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study
MeSH Terms :
Gene Fusion*
Gene Rearrangement*
Immunohistochemistry*
Biomarkers, Tumor/*genetics
Oncogene Proteins, Fusion/*genetics
Receptor, trkC/*genetics
Salivary Gland Neoplasms/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; France ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Multiplex Polymerase Chain Reaction ; Phenotype ; Predictive Value of Tests ; Reproducibility of Results ; Retrospective Studies ; Reverse Transcriptase Polymerase Chain Reaction ; Salivary Gland Neoplasms/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Morphologically malignant nodular fasciitis with CALD1-USP6 fusion.
Autorzy :
Papke DJ Jr; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Oliveira AM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Chou MM; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA.
Fletcher CDM; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. .
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Nov; Vol. 479 (5), pp. 1007-1012. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Case Reports
MeSH Terms :
Gene Fusion*
Translocation, Genetic*
Biomarkers, Tumor/*genetics
Calmodulin-Binding Proteins/*genetics
Fasciitis/*genetics
Myofibroblasts/*pathology
Soft Tissue Neoplasms/*genetics
Ubiquitin Thiolesterase/*genetics
Child ; Fasciitis/pathology ; Fasciitis/surgery ; Genetic Predisposition to Disease ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Phenotype ; Prognosis ; Soft Tissue Neoplasms/pathology ; Soft Tissue Neoplasms/surgery
Raport
Tytuł :
Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.
Autorzy :
Hasegawa N; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.; Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kohsaka S; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.
Kurokawa K; Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shinno Y; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.
Takeda Nakamura I; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.; Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ueno T; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.
Kojima S; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.
Kawazu M; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.
Suehara Y; Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ishijima M; Department of Medicine for Orthopaedics and Motor Organ, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Goto Y; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.
Kojima Y; Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Yonemori K; Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Hayashi T; Department of Human Pathology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Saito T; Department of Human Pathology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Shukuya T; Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Takahashi F; Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Takahashi K; Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Mano H; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Oct; Vol. 112 (10), pp. 4393-4403. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cell-Free Nucleic Acids*/isolation & purification
Gene Fusion*
Anaplastic Lymphoma Kinase/*genetics
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Protein-Tyrosine Kinases/*genetics
Proto-Oncogene Proteins/*genetics
Proto-Oncogene Proteins c-ret/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Biopsy ; Carbazoles/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/pathology ; Crizotinib/therapeutic use ; Cytoskeletal Proteins/genetics ; Disease Progression ; Drug Resistance, Neoplasm/genetics ; Female ; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)/genetics ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Liquid Biopsy/methods ; Lung/pathology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Oncogene Proteins, Fusion/genetics ; Oncogene Proteins, Fusion/isolation & purification ; Piperidines/therapeutic use ; Protein Kinase Inhibitors/therapeutic use ; RNA, Messenger/isolation & purification ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Novel fusion sarcomas including targetable NTRK and ALK.
Autorzy :
Chen T; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Pathology, United States of America.
Wang Y; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Pathology, United States of America.
Goetz L; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Pathology, United States of America.
Corey Z; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America.
Dougher MC; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America.
Smith JD; Georgetown University, United States of America.
Fox EJ; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Orthopaedics, United States of America.
Freiberg AS; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Pediatrics, United States of America.
Flemming D; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Radiology, United States of America.
Fanburg-Smith JC; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Pathology, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Orthopaedics, United States of America; Penn State Health/Milton S. Hershey Medical Center/Penn State College of Medicine, Department of Pediatrics, United States of America. Electronic address: .
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Źródło :
Annals of diagnostic pathology [Ann Diagn Pathol] 2021 Oct; Vol. 54, pp. 151800. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Gene Fusion*
Biomarkers, Tumor/*genetics
Femoral Neoplasms/*genetics
Head and Neck Neoplasms/*genetics
Sarcoma/*genetics
Soft Tissue Neoplasms/*genetics
Thoracic Neoplasms/*genetics
Adolescent ; Adult ; Aged ; Algorithms ; Antineoplastic Agents/therapeutic use ; Child ; Child, Preschool ; Extremities/pathology ; Female ; Femoral Neoplasms/diagnosis ; Femoral Neoplasms/drug therapy ; Femoral Neoplasms/pathology ; Head and Neck Neoplasms/diagnosis ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/pathology ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Phenotype ; Prognosis ; Sarcoma/diagnosis ; Sarcoma/drug therapy ; Sarcoma/pathology ; Soft Tissue Neoplasms/diagnosis ; Soft Tissue Neoplasms/drug therapy ; Soft Tissue Neoplasms/pathology ; Thoracic Neoplasms/diagnosis ; Thoracic Neoplasms/drug therapy ; Thoracic Neoplasms/pathology ; Thoracic Wall/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
GOPC-ROS1 mosaicism in agminated Spitz naevi: report of two cases.
Autorzy :
Goto K; Department of Pathology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan.; Department of Pathology, Itabashi Central Clinical Laboratory, Tokyo, Japan.; Department of Diagnostic Pathology, Shizuoka Cancer Center Hospital, Nagaizumi, Japan.; Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, Japan.; Department of Dermatology, Hyogo Cancer Center, Akashi, Japan.
Pissaloux D; Department of Biopathology, Center Léon Bérard, 28, rue Laennec, 69008, Lyon, France.; Centre Léon Bérard, Cancer Research Center of Lyon, Equipe Labellisée Ligue contre le Cancer, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Lyon, France.
Kauer F; MVZ Pathologie am Bundeswehrkrankenhaus, Berlin, Germany.
Huriet V; Centre de Pathologie, Nancy, France.
Tirode F; Department of Biopathology, Center Léon Bérard, 28, rue Laennec, 69008, Lyon, France.; Centre Léon Bérard, Cancer Research Center of Lyon, Equipe Labellisée Ligue contre le Cancer, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Lyon, France.
de la Fouchardière A; Department of Biopathology, Center Léon Bérard, 28, rue Laennec, 69008, Lyon, France. .; Centre Léon Bérard, Cancer Research Center of Lyon, Equipe Labellisée Ligue contre le Cancer, Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Lyon, France. .
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Sep; Vol. 479 (3), pp. 559-564. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Fusion*
Mosaicism*
Adaptor Proteins, Signal Transducing/*genetics
Biomarkers, Tumor/*genetics
Golgi Matrix Proteins/*genetics
Nevus, Epithelioid and Spindle Cell/*genetics
Protein-Tyrosine Kinases/*genetics
Proto-Oncogene Proteins/*genetics
Skin Neoplasms/*genetics
Female ; Genetic Predisposition to Disease ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Melanocytes/pathology ; Nevus, Epithelioid and Spindle Cell/pathology ; Phenotype ; Sequence Analysis, RNA ; Skin Neoplasms/pathology ; Whole Exome Sequencing ; Young Adult
Czasopismo naukowe
Tytuł :
A Novel NFIX-STAT6 Gene Fusion in Solitary Fibrous Tumor: A Case Report.
Autorzy :
Moura DS; Institute of Biomedicine of Seville (IBiS, CSIC, HUVR, US), 41013 Seville, Spain.
Díaz-Martín J; Institute of Biomedicine of Seville (IBiS, CSIC, HUVR, US), 41013 Seville, Spain.; Pathology Department, Hospital Virgen del Rocío, 41013 Sevilla, Spain.; Centro de Investigación Biomédica en Red del Cáncer (CIBERONC), 28029 Madrid, Spain.
Bagué S; Pathology Department-CIBERONC, Sant Pau Hospital, 08041 Barcelona, Spain.
Orellana-Fernandez R; Pathology Department-CIBERONC, Sant Pau Hospital, 08041 Barcelona, Spain.
Sebio A; Medical Oncology Department, Sant Pau Hospital, 08041 Barcelona, Spain.
Mondaza-Hernandez JL; Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS/FJD), 28015 Madrid, Spain.
Salguero-Aranda C; Institute of Biomedicine of Seville (IBiS, CSIC, HUVR, US), 41013 Seville, Spain.; Pathology Department, Hospital Virgen del Rocío, 41013 Sevilla, Spain.; Centro de Investigación Biomédica en Red del Cáncer (CIBERONC), 28029 Madrid, Spain.
Rojo F; Pathology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.
Hindi N; Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS/FJD), 28015 Madrid, Spain.; Medical Oncology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.; General de Villalba University Hospital, 28400 Madrid, Spain.
Fletcher CDM; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
Martin-Broto J; Fundacion Jimenez Diaz University Hospital Health Research Institute (IIS/FJD), 28015 Madrid, Spain.; Medical Oncology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.; General de Villalba University Hospital, 28400 Madrid, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 13; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Gene Fusion*
NFI Transcription Factors/*genetics
Oncogene Proteins, Fusion/*genetics
STAT6 Transcription Factor/*genetics
Solitary Fibrous Tumors/*genetics
Solitary Fibrous Tumors/*pathology
Aged ; Female ; Humans ; Prognosis
Czasopismo naukowe
Tytuł :
Novel partners of USP6 gene in a spectrum of bone and soft tissue lesions.
Autorzy :
Legrand M; Service d'anatomie et cytologie pathologiques, CHRU de Tours, Avenue de la République, 37044 Cedex 9, Tours, France.
Jourdan ML; Plateforme de Génétique moléculaire des cancers, CHRU de Tours, Tours, France.
Tallet A; Plateforme de Génétique moléculaire des cancers, CHRU de Tours, Tours, France.
Collin C; Plateforme de Génétique moléculaire des cancers, CHRU de Tours, Tours, France.
Audard V; Service d'anatomie et cytologie pathologiques, Hôpital Cochin, Paris, France.
Larousserie F; Service d'anatomie et cytologie pathologiques, Hôpital Cochin, Paris, France.
Aubert S; Service d'anatomie et cytologie pathologiques, CHU de Lille, Lille, France.
Gomez-Brouchet A; CRB Cancer, IUCT-oncopole, Toulouse, France.
Bouvier C; Service d'anatomie et cytologie pathologiques, CHU de Marseille La Timone, Marseille, France.
de Pinieux G; Service d'anatomie et cytologie pathologiques, CHRU de Tours, Avenue de la République, 37044 Cedex 9, Tours, France. .; PRES Centre-Val de Loire Université, Université François-Rabelais de Tours, Tours, France. .
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Jul; Vol. 479 (1), pp. 147-156. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Gene Fusion*
Gene Rearrangement*
Bone Cysts, Aneurysmal/*genetics
Fasciitis/*genetics
Myositis Ossificans/*genetics
Ubiquitin Thiolesterase/*genetics
Adolescent ; Adult ; Bone Cysts, Aneurysmal/pathology ; Child ; Databases, Factual ; Fasciitis/pathology ; Female ; France ; Genetic Predisposition to Disease ; Humans ; Male ; Middle Aged ; Myositis Ossificans/pathology ; Phenotype ; Retrospective Studies ; Young Adult
Czasopismo naukowe
Tytuł :
Atypical nodular fasciitis with a novel PAFAH1B1-USP6 fusion in a 22-month-old boy.
Autorzy :
Qiu Y; Department of Pathology, West China Hospital, Sichuan University, Guoxuexiang 37, Chengdu, 610041, Sichuan, China.
Peng R; Department of Pathology, West China Hospital, Sichuan University, Guoxuexiang 37, Chengdu, 610041, Sichuan, China.
Chen H; Department of Pathology, West China Hospital, Sichuan University, Guoxuexiang 37, Chengdu, 610041, Sichuan, China.
Zhuang H; Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
He X; Department of Pathology, West China Hospital, Sichuan University, Guoxuexiang 37, Chengdu, 610041, Sichuan, China.
Zhang H; Department of Pathology, West China Hospital, Sichuan University, Guoxuexiang 37, Chengdu, 610041, Sichuan, China. .
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Sep; Vol. 479 (3), pp. 623-629. Date of Electronic Publication: 2020 Nov 08.
Typ publikacji :
Case Reports
MeSH Terms :
Gene Fusion*
1-Alkyl-2-acetylglycerophosphocholine Esterase/*genetics
Fasciitis/*genetics
Microtubule-Associated Proteins/*genetics
Ubiquitin Thiolesterase/*genetics
Fasciitis/pathology ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans ; In Situ Hybridization, Fluorescence ; Infant ; Male ; Mitosis ; Phenotype
Raport
Tytuł :
Pan-TRK Immunohistochemistry: An Example-Based Practical Approach to Efficiently Identify Patients With NTRK Fusion Cancer.
Autorzy :
Conde E; From Pathology and Laboratory of Therapeutic Targets, Hospital Universitario HM Sanchinarro, HMHospitales, CIBERONC, Madrid, Spain (Conde, Lopez-Rios).
Hernandez S; Pathology and Laboratory of Therapeutic Targets, Hospital Universitario HM Sanchinarro, HMHospitales, Madrid, Spain (Hernandez, Sanchez, Alonso, Martinez).
Sanchez E; Pathology and Laboratory of Therapeutic Targets, Hospital Universitario HM Sanchinarro, HMHospitales, Madrid, Spain (Hernandez, Sanchez, Alonso, Martinez).
Regojo RM; Pathology, Hospital Universitario La Paz, Madrid, Spain (Regojo).
Camacho C; Pathology, Complejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, Spain (Camacho). Conde and Hernandez contributed equally as co-first authors.
Alonso M; Pathology and Laboratory of Therapeutic Targets, Hospital Universitario HM Sanchinarro, HMHospitales, Madrid, Spain (Hernandez, Sanchez, Alonso, Martinez).
Martinez R; Pathology and Laboratory of Therapeutic Targets, Hospital Universitario HM Sanchinarro, HMHospitales, Madrid, Spain (Hernandez, Sanchez, Alonso, Martinez).
Lopez-Rios F; From Pathology and Laboratory of Therapeutic Targets, Hospital Universitario HM Sanchinarro, HMHospitales, CIBERONC, Madrid, Spain (Conde, Lopez-Rios).
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Źródło :
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2021 Aug 01; Vol. 145 (8), pp. 1031-1040.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Fusion*
Immunohistochemistry*
Biomarkers, Tumor/*genetics
Membrane Glycoproteins/*genetics
Neoplasms/*genetics
Receptor, trkA/*genetics
Receptor, trkB/*genetics
Receptor, trkC/*genetics
Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans ; In Situ Hybridization, Fluorescence ; Neoplasms/pathology ; Phenotype ; Predictive Value of Tests ; Prognosis ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts.
Autorzy :
Wang Y; MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.; Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Science, Beijing, China.
Zou Q; MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Li F; MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.; Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Science, Beijing, China.
Zhao W; MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Xu H; MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Zhang W; MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Deng H; MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Yang X; MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 30; Vol. 12 (1), pp. 4645. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Fusion*
RNA Splicing*
Trans-Splicing*
Gene Expression Profiling/*methods
RNA/*genetics
Transcriptome/*genetics
A549 Cells ; Cell Line, Tumor ; Computational Biology/methods ; Humans ; In Situ Hybridization, Fluorescence/methods ; Models, Genetic ; PC-3 Cells ; RNA Precursors/genetics ; Reverse Transcriptase Polymerase Chain Reaction/methods
Czasopismo naukowe
Tytuł :
JAK2 Rearrangements Are a Recurrent Alteration in CD30+ Systemic T-Cell Lymphomas With Anaplastic Morphology.
Autorzy :
Fitzpatrick MJ; Department of Pathology, Massachusetts General Hospital, Harvard Medical School.
Massoth LR; Department of Pathology, Massachusetts General Hospital, Harvard Medical School.
Marcus C; Foundation Medicine Inc., Cambridge, MA.
Vergilio JA; Foundation Medicine Inc., Cambridge, MA.
Severson E; Foundation Medicine Inc., Cambridge, MA.
Duncan D; Foundation Medicine Inc., Cambridge, MA.
Ramkissoon SH; Foundation Medicine Inc., Cambridge, MA.; Wake Forest Comprehensive Cancer Center and Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC.
Hasserjian RP; Department of Pathology, Massachusetts General Hospital, Harvard Medical School.
Kim AS; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston.
Sohani AR; Department of Pathology, Massachusetts General Hospital, Harvard Medical School.
Williams EA; Foundation Medicine Inc., Cambridge, MA.; Department of Pathology, Department of Dermatology, UCSF Dermatopathology Service, University of California San Francisco, San Francisco, CA.
Nardi V; Department of Pathology, Massachusetts General Hospital, Harvard Medical School.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 Jul 01; Vol. 45 (7), pp. 895-904.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Gene Fusion*
Gene Rearrangement*
Biomarkers, Tumor/*genetics
Janus Kinase 2/*genetics
Ki-1 Antigen/*analysis
Lymphoma, Large-Cell, Anaplastic/*genetics
Lymphoma, T-Cell, Peripheral/*genetics
Adult ; Aged ; Aged, 80 and over ; Genetic Predisposition to Disease ; Humans ; Lewis X Antigen/analysis ; Lymphoma, Large-Cell, Anaplastic/enzymology ; Lymphoma, Large-Cell, Anaplastic/immunology ; Lymphoma, T-Cell, Peripheral/enzymology ; Lymphoma, T-Cell, Peripheral/immunology ; Male ; Middle Aged ; Phenotype ; Poly(A)-Binding Protein I/genetics ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study.
Autorzy :
Gainor JF; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. Electronic address: .
Curigliano G; Department of Oncology and Hemato-Oncology, University of Milan and European Institute of Oncology, IRCCS, Milan, Italy.
Kim DW; Department of Internal Medicine, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, South Korea.
Lee DH; Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Besse B; Department of Cancer Medicine, Gustave Roussy Cancer Centre, Villejuif, France; Paris-Saclay University, Orsay, France.
Baik CS; Division of Oncology, Department of Medicine, University of Washington, Seattle, WA, USA.
Doebele RC; Division of Medical Oncology, University of Colorado School of Medicine, Aurora, CO, USA.
Cassier PA; Department of Medicine, Centre Léon Bérard, Lyon, France.
Lopes G; Miller School of Medicine and Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.
Tan DSW; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
Garralda E; Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Barcelona, Spain.
Paz-Ares LG; Medical Oncology Department, Hospital Universitario 12 de Octubre and Spanish National Cancer Research Center, Madrid, Spain.
Cho BC; Division of Medical Oncology, Department of Internal Medicine and Yonsei Cancer Center, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Gadgeel SM; Division of Hematology and Oncology, Department of Medicine, University of Michigan, Ann Arbor, MI, USA.
Thomas M; Department of Thoracic Oncology, Translational Lung Research Center Heidelberg, Thoraxklinik Heidelberg University Hospital, Heidelberg, Germany.
Liu SV; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.
Taylor MH; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.
Mansfield AS; Division of Medical Oncology, Mayo Clinic, Rochester, MN, USA.
Zhu VW; Division of Hematology-Oncology, Department of Medicine, University of California Irvine, Orange, CA, USA.
Clifford C; Clinical Operations, Blueprint Medicines, Cambridge, MA, USA.
Zhang H; Biostatistics, Blueprint Medicines, Cambridge, MA, USA.
Palmer M; Translational Medicine, Blueprint Medicines, Cambridge, MA, USA.
Green J; Clinical Development, Blueprint Medicines, Cambridge, MA, USA.
Turner CD; Clinical Development, Blueprint Medicines, Cambridge, MA, USA.
Subbiah V; Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
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Źródło :
The Lancet. Oncology [Lancet Oncol] 2021 Jul; Vol. 22 (7), pp. 959-969. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Fusion*
Antineoplastic Agents/*therapeutic use
Biomarkers, Tumor/*genetics
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Neoplasms/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Proto-Oncogene Proteins c-ret/*antagonists & inhibitors
Proto-Oncogene Proteins c-ret/*genetics
Pyrazoles/*therapeutic use
Pyridines/*therapeutic use
Pyrimidines/*therapeutic use
Aged ; Antineoplastic Agents/adverse effects ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Female ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Protein Kinase Inhibitors/adverse effects ; Pyrazoles/adverse effects ; Pyridines/adverse effects ; Pyrimidines/adverse effects ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Diagnostic Utility of a Custom 34-Gene Anchored Multiplex PCR-Based Next-Generation Sequencing Fusion Panel for the Diagnosis of Bone and Soft Tissue Neoplasms With Identification of Novel USP6 Fusion Partners in Aneurysmal Bone Cysts.
Autorzy :
Dermawan JK; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Cheng YW; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Tu ZJ; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Meyer A; The Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City (Meyer).
Habeeb O; The Department of Anatomic Pathology, Middlemore Hospital, Counties Manukau District Health Board, Auckland, New Zealand (Habeeb).
Zou Y; The Department of Pathology, Kaiser Permanente Oakland Medical Center, Oakland, California (Zou).
Goldblum JR; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Billings SD; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Kilpatrick SE; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Reith JD; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Shurtleff SA; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Farkas DH; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Rubin BP; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
Azzato EM; From Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dermawan, Cheng, Tu, Goldblum, Billings, Kilpatrick, Reith, Shurtleff, Farkas, Rubin, Azzato).
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Źródło :
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2021 Jul 01; Vol. 145 (7), pp. 851-863.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gene Fusion*
Multiplex Polymerase Chain Reaction*
Transcriptome*
Biomarkers, Tumor/*genetics
Bone Cysts, Aneurysmal/*genetics
Bone Neoplasms/*genetics
Soft Tissue Neoplasms/*genetics
Ubiquitin Thiolesterase/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bone Cysts, Aneurysmal/pathology ; Bone Neoplasms/pathology ; Child ; Child, Preschool ; Diagnosis, Differential ; Female ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans ; Infant ; Male ; Middle Aged ; Predictive Value of Tests ; Reproducibility of Results ; Soft Tissue Neoplasms/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Genetic Analysis of Protein Translocation.
Autorzy :
Silhavy TJ; Department of Molecular Biology, Princeton University, 310 Lewis Thomas Laboratory, Washington Road, Princeton, NJ, 08544, USA. .
Mitchell AM; Department of Molecular Biology, Princeton University, 310 Lewis Thomas Laboratory, Washington Road, Princeton, NJ, 08544, USA.
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Źródło :
The protein journal [Protein J] 2019 Jun; Vol. 38 (3), pp. 217-228.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Artificial Gene Fusion*
Escherichia coli/*metabolism
Escherichia coli Proteins/*metabolism
beta-Galactosidase/*genetics
Cell Membrane/metabolism ; Escherichia coli/genetics ; Escherichia coli Proteins/genetics ; Gene Fusion/genetics ; Lac Operon ; Protein Transport/genetics ; Recombinant Fusion Proteins/metabolism ; SEC Translocation Channels/metabolism
Czasopismo naukowe
Tytuł :
Gene fusion neoantigens: Emerging targets for cancer immunotherapy.
Autorzy :
Wang Y; The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School & Clinical Cancer Institute of Nanjing University, Nanjing, 210008, China.
Shi T; The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School & Clinical Cancer Institute of Nanjing University, Nanjing, 210008, China.
Song X; The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School & Clinical Cancer Institute of Nanjing University, Nanjing, 210008, China.
Liu B; The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School & Clinical Cancer Institute of Nanjing University, Nanjing, 210008, China.
Wei J; The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School & Clinical Cancer Institute of Nanjing University, Nanjing, 210008, China. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2021 May 28; Vol. 506, pp. 45-54. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Gene Fusion*
Cancer Vaccines/*immunology
Immunotherapy/*methods
Neoplasms/*therapy
Antigens, Neoplasm/genetics ; Antigens, Neoplasm/immunology ; Humans ; Immunotherapy, Adoptive ; Tumor Microenvironment
Czasopismo naukowe

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