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Wyszukujesz frazę ""Gene Knockdown Techniques"" wg kryterium: Temat


Tytuł :
BMAL1 knockdown promoted apoptosis and reduced testosterone secretion in TM3 Leydig cell line.
Autorzy :
Ding H; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Zhao J; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Liu H; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Wang J; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. Electronic address: .
Lu W; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Jul 15; Vol. 747, pp. 144672. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/genetics
Gene Knockdown Techniques*
ARNTL Transcription Factors/*metabolism
Testosterone/*metabolism
ARNTL Transcription Factors/genetics ; Animals ; Cell Line ; Gene Expression Regulation ; Leydig Cells/metabolism ; Male ; Mice ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Testosterone/biosynthesis ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
TRIM59 knockdown blocks cisplatin resistance in A549/DDP cells through regulating PTEN/AKT/HK2.
Autorzy :
He R; Department of Thoracic Oncology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, PR China.
Liu H; Department of Thoracic Oncology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, PR China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Jul 15; Vol. 747, pp. 144553. Date of Electronic Publication: 2020 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Neoplasm*/drug effects
Gene Knockdown Techniques*
Cisplatin/*pharmacology
Hexokinase/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
PTEN Phosphohydrolase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Tripartite Motif Proteins/*metabolism
A549 Cells ; Animals ; Apoptosis/drug effects ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Down-Regulation/drug effects ; Down-Regulation/genetics ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Glycolysis/drug effects ; Glycolysis/genetics ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Mice, Inbred BALB C ; Mice, Nude ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Ubiquitination
Czasopismo naukowe
Tytuł :
Transcriptomic Analysis of Pulmonary Microvascular Endothelial Cells with IQGAP1 Knockdown.
Autorzy :
Su S; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xu A; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Chen Y; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Li W; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zha X; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, China.
Wang Y; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, China.
Sun G; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2020 Jul; Vol. 39 (7), pp. 1127-1140. Date of Electronic Publication: 2020 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gene Knockdown Techniques*
Endothelial Cells/*metabolism
Lung/*blood supply
Microvessels/*cytology
ras GTPase-Activating Proteins/*deficiency
ras GTPase-Activating Proteins/*genetics
Animals ; Gene Ontology ; Rats
Czasopismo naukowe
Tytuł :
TRAF4 knockdown triggers synergistic lethality with simultaneous PARP1 inhibition in endometrial cancer.
Autorzy :
Tang L; Department of Obstetrics and Gynecology, Affiliated Hospital of Guilin Medical University, Guangxi Zhuang Autonomous Region, Guilin City, 541001, China.
Wang M; Department of Obstetrics and Gynecology, Affiliated Hospital of Guilin Medical University, Guangxi Zhuang Autonomous Region, Guilin City, 541001, China.
Jiang L; Department of Obstetrics and Gynecology, Affiliated Hospital of Guilin Medical University, Guangxi Zhuang Autonomous Region, Guilin City, 541001, China.
Zeng C; Department of Obstetrics and Gynecology, Guangdong Province, The Third Affiliated Hospital of Southern Medical University, No. 183 Zhongshan Avenue West, Tianhe District, Guangzhou City, 510630, China. .
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Źródło :
Human cell [Hum Cell] 2020 Jul; Vol. 33 (3), pp. 801-809. Date of Electronic Publication: 2020 May 09.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
Endometrial Neoplasms/*drug therapy
Endometrial Neoplasms/*genetics
Phthalazines/*pharmacology
Phthalazines/*therapeutic use
Piperazines/*pharmacology
Piperazines/*therapeutic use
Poly (ADP-Ribose) Polymerase-1/*antagonists & inhibitors
Animals ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; DNA Breaks, Double-Stranded ; Disease Models, Animal ; Endometrial Neoplasms/pathology ; Female ; Gene Expression ; Humans ; Mice ; Molecular Targeted Therapy ; Phosphorylation/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; TNF Receptor-Associated Factor 4/genetics ; TNF Receptor-Associated Factor 4/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Knockdown of fibronectin extra domain B suppresses TGF-β1-mediated cell proliferation and collagen deposition in keloid fibroblasts via AKT/ERK signaling pathway.
Autorzy :
Cui J; Department of Dermatology, Yanbian University Hospital, Yanji, 133000, China. Electronic address: .
Li Z; Department of Dermatology, Yanbian University Hospital, Yanji, 133000, China. Electronic address: .
Jin C; Department of Dermatology, Yanbian University Hospital, Yanji, 133000, China. Electronic address: .
Jin Z; Department of Dermatology, Yanbian University Hospital, Yanji, 133000, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Jun 11; Vol. 526 (4), pp. 1131-1137. Date of Electronic Publication: 2020 Apr 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Knockdown Techniques*
MAP Kinase Signaling System*/drug effects
Collagen/*metabolism
Fibroblasts/*metabolism
Fibronectins/*chemistry
Fibronectins/*metabolism
Keloid/*pathology
Transforming Growth Factor beta1/*pharmacology
Apoptosis ; Cell Proliferation/drug effects ; Fibroblasts/drug effects ; Humans ; Male ; Protein Domains ; Proto-Oncogene Proteins c-akt/metabolism ; Smad Proteins/metabolism ; Structure-Activity Relationship ; Up-Regulation
Czasopismo naukowe
Tytuł :
STIM1 knock-down decreases the affinity of obinutuzumab for CD20 by altering CD20 localization to Triton-soluble membrane.
Autorzy :
Heo W; Department of Pharmacology and Brain, Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Jin N; Department of Pharmacology and Brain, Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Park MS; Department of Pharmacology and Brain, Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Kim HY; Department of Pharmacology and Brain, Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Yoon SM; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Korea.
Lee J; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Korea.
Kim JY; Department of Pharmacology and Brain, Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
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Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 2020 Jun; Vol. 200 (3), pp. 260-271. Date of Electronic Publication: 2020 Feb 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Knockdown Techniques*
Antibodies, Monoclonal, Humanized/*immunology
Antigens, CD20/*immunology
Cell Membrane/*immunology
Neoplasm Proteins/*immunology
Stromal Interaction Molecule 1/*immunology
Animals ; Antigens, CD20/genetics ; CHO Cells ; Cell Membrane/genetics ; Cricetulus ; Humans ; Neoplasm Proteins/genetics ; Octoxynol/chemistry ; Solubility ; Stromal Interaction Molecule 1/genetics
Czasopismo naukowe
Tytuł :
Cyclophilin a knokdown inhibits cell migration and invasion through the suppression of epithelial-mesenchymal transition in colorectal cancer cells.
Autorzy :
Yamamoto T; Pathological and Biomolecule Analyses Laboratory, Faculty of Pharmacy, Kindai University, Osaka, Japan.
Takakura H; Department of Molecular-Targeting Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan; Department of Drug Discovery Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Mitamura K; Pathological and Biomolecule Analyses Laboratory, Faculty of Pharmacy, Kindai University, Osaka, Japan.
Taga A; Pathological and Biomolecule Analyses Laboratory, Faculty of Pharmacy, Kindai University, Osaka, Japan; Antiaging Center, Kindai University, Osaka, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 May 21; Vol. 526 (1), pp. 55-61. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement*
Epithelial-Mesenchymal Transition*/genetics
Gene Knockdown Techniques*
Colorectal Neoplasms/*pathology
Cyclophilin A/*metabolism
Cell Line, Tumor ; Cell Proliferation/genetics ; Colorectal Neoplasms/genetics ; Cyclophilin A/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Invasiveness ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
ABHD12 Knockdown Suppresses Breast Cancer Cell Proliferation, Migration and Invasion.
Autorzy :
Jun S; Department of Premedical Sciences, College of Medicine, Chosun University, Gwangju, Republic of Korea.
Kim SW; Department of Neurosurgery, College of Medicine, Chosun University, Gwangju, Republic of Korea.
Lim JY; Department of Premedical Sciences, College of Medicine, Chosun University, Gwangju, Republic of Korea.
Park SJ; Department of Premedical Sciences, College of Medicine, Chosun University, Gwangju, Republic of Korea .
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Źródło :
Anticancer research [Anticancer Res] 2020 May; Vol. 40 (5), pp. 2601-2611.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Movement*/genetics
Gene Knockdown Techniques*
Breast Neoplasms/*genetics
Breast Neoplasms/*pathology
Monoacylglycerol Lipases/*metabolism
Cell Line, Tumor ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Monoacylglycerol Lipases/genetics ; Neoplasm Invasiveness ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Receptors, Cannabinoid/metabolism ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
LncRNA LINC00313 Knockdown Inhibits Tumorigenesis and Metastasis in Human Osteosarcoma by Upregulating FOSL2 through Sponging miR-342-3p.
Autorzy :
Chen H; Department of Orthopedics, The Sixth Affiliated Hospital of Xinjiang Medical University, Xinjiang, China. .
Wahafu P; Department of Orthopedics, The Sixth Affiliated Hospital of Xinjiang Medical University, Xinjiang, China.
Wang L; Department of Orthopedics, The Sixth Affiliated Hospital of Xinjiang Medical University, Xinjiang, China.
Chen X; Department of Orthopedics, The Sixth Affiliated Hospital of Xinjiang Medical University, Xinjiang, China.
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Źródło :
Yonsei medical journal [Yonsei Med J] 2020 May; Vol. 61 (5), pp. 359-370.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
Carcinogenesis/*pathology
Fos-Related Antigen-2/*genetics
MicroRNAs/*metabolism
Osteosarcoma/*genetics
Osteosarcoma/*pathology
RNA, Long Noncoding/*genetics
Up-Regulation/*genetics
Adult ; Base Sequence ; Bone Neoplasms/genetics ; Bone Neoplasms/pathology ; Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Female ; Fos-Related Antigen-2/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; MicroRNAs/genetics ; Neoplasm Metastasis ; RNA, Long Noncoding/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
PLK1 Knockdown Inhibits Cell Proliferation and Cell Apoptosis, and PLK1 Is Negatively Regulated by miR-4779 in Osteosarcoma Cells.
Autorzy :
Zhu J; Department of Orthopaedics, The 4th Affiliated Hospital of China Medical University, Shenyang, China.
Cui K; Department of Orthopaedics, The 4th Affiliated Hospital of China Medical University, Shenyang, China.
Cui Y; Department of Orthopaedics, The 4th Affiliated Hospital of China Medical University, Shenyang, China.
Ma C; Department of Orthopaedics, The 4th Affiliated Hospital of China Medical University, Shenyang, China.
Zhang Z; Department of Orthopaedics, The 4th Affiliated Hospital of China Medical University, Shenyang, China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2020 May; Vol. 39 (5), pp. 747-755. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
Apoptosis/*genetics
Cell Cycle Proteins/*deficiency
Cell Cycle Proteins/*genetics
MicroRNAs/*genetics
Protein-Serine-Threonine Kinases/*deficiency
Protein-Serine-Threonine Kinases/*genetics
Proto-Oncogene Proteins/*deficiency
Proto-Oncogene Proteins/*genetics
Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Survival/genetics ; Cellular Senescence/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans
Czasopismo naukowe
Tytuł :
Small G protein signaling modulator 3 (SGSM3) knockdown attenuates apoptosis and cardiogenic differentiation in rat mesenchymal stem cells exposed to hypoxia.
Autorzy :
Jung SE; Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea.
Choi JW; Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea.
Moon H; Department of Integrated Omics for Biomedical Sciences, Graduate School, Yonsei University, Seoul, Republic of Korea.
Oh S; Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea.
Lim S; Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea.; International St. Mary's Hospital, Catholic Kwandong University, Incheon Metropolitan City, Republic of Korea.
Lee S; Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea.; International St. Mary's Hospital, Catholic Kwandong University, Incheon Metropolitan City, Republic of Korea.
Kim SW; Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea.; International St. Mary's Hospital, Catholic Kwandong University, Incheon Metropolitan City, Republic of Korea.
Hwang KC; Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea.; International St. Mary's Hospital, Catholic Kwandong University, Incheon Metropolitan City, Republic of Korea.
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Źródło :
PloS one [PLoS One] 2020 Apr 09; Vol. 15 (4), pp. e0231272. Date of Electronic Publication: 2020 Apr 09 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Knockdown Techniques*
Apoptosis/*drug effects
Cell Differentiation/*drug effects
Mesenchymal Stem Cells/*cytology
Mesenchymal Stem Cells/*metabolism
Monomeric GTP-Binding Proteins/*metabolism
Myocytes, Cardiac/*metabolism
Animals ; Biomarkers/metabolism ; Cell Hypoxia/drug effects ; Connexin 43/metabolism ; Gap Junctions/drug effects ; Gap Junctions/metabolism ; Gene Expression Regulation/drug effects ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mesenchymal Stem Cells/drug effects ; Myocytes, Cardiac/drug effects ; Oxygen/pharmacology ; Rats, Sprague-Dawley ; Stress, Physiological/drug effects ; Time Factors ; Wnt Signaling Pathway/drug effects
Czasopismo naukowe
Tytuł :
Knockdown of long non-coding RNA CCAT1 suppresses proliferation and EMT of human cervical cancer cell lines by down-regulating Runx2.
Autorzy :
Li R; Department of Obstetrics and Gynecology, The Affiliated Hospital of Jilin Medical University, Jilin 132013, China. Electronic address: .
Liu J; Department of Gynecology, Jilin Provincial Cancer Hospital, Changchun 130000, China.
Qi J; Department of Gynecology, Jilin Provincial Cancer Hospital, Changchun 130000, China.
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Źródło :
Experimental and molecular pathology [Exp Mol Pathol] 2020 Apr; Vol. 113, pp. 104380. Date of Electronic Publication: 2020 Jan 11.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
Core Binding Factor Alpha 1 Subunit/*genetics
Down-Regulation/*genetics
Epithelial-Mesenchymal Transition/*genetics
RNA, Long Noncoding/*metabolism
Uterine Cervical Neoplasms/*genetics
Animals ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Invasiveness ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; Tumor Burden
Czasopismo naukowe
Tytuł :
Inhibition of miR-217 Protects Against Myocardial Ischemia-Reperfusion Injury Through Inactivating NF-κB and MAPK Pathways.
Autorzy :
Li Y; Department of Cardiovascular Medicine, Heji Hospital Affiliated to Changzhi Medical College, 271 East Taihang Street, Changzhi, 046000, Shanxi, China. .
Fei L; Department of Cardiovascular Medicine, Heji Hospital Affiliated to Changzhi Medical College, 271 East Taihang Street, Changzhi, 046000, Shanxi, China.
Wang J; Department of Cardiovascular Medicine, Heji Hospital Affiliated to Changzhi Medical College, 271 East Taihang Street, Changzhi, 046000, Shanxi, China.
Niu Q; Department of Cardiovascular Medicine, Heji Hospital Affiliated to Changzhi Medical College, 271 East Taihang Street, Changzhi, 046000, Shanxi, China.
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Źródło :
Cardiovascular engineering and technology [Cardiovasc Eng Technol] 2020 Apr; Vol. 11 (2), pp. 219-227. Date of Electronic Publication: 2020 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
Antagomirs/*administration & dosage
MicroRNAs/*metabolism
Mitogen-Activated Protein Kinases/*metabolism
Myocardial Infarction/*prevention & control
Myocardial Reperfusion Injury/*prevention & control
Myocytes, Cardiac/*enzymology
NF-kappa B/*metabolism
Animals ; Cell Line ; Disease Models, Animal ; Dual-Specificity Phosphatases/genetics ; Dual-Specificity Phosphatases/metabolism ; Male ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Myocardial Infarction/enzymology ; Myocardial Infarction/genetics ; Myocardial Infarction/pathology ; Myocardial Reperfusion Injury/enzymology ; Myocardial Reperfusion Injury/genetics ; Myocardial Reperfusion Injury/pathology ; Myocytes, Cardiac/pathology ; Phosphorylation ; Signal Transduction
Czasopismo naukowe
Tytuł :
Ceramide synthase 2 knockdown suppresses trophozoite growth, migration, in vitro encystment and excystment of Entamoeba invadens.
Autorzy :
Jáuregui-Wade JM; Department of Biochemistry, CINVESTAV-IPN, P.O. Box 14-740, 07360, Ciudad de México, Mexico.
Cerbón-Solórzano J; Department of Biochemistry, CINVESTAV-IPN, P.O. Box 14-740, 07360, Ciudad de México, Mexico.
Ávila-García R; Department of Biochemistry, CINVESTAV-IPN, P.O. Box 14-740, 07360, Ciudad de México, Mexico.
Ayala-Sumuano JT; Idix S.A. de C.V, Querétaro, Mexico.
Valdés J; Department of Biochemistry, CINVESTAV-IPN, P.O. Box 14-740, 07360, Ciudad de México, Mexico. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Mar 26; Vol. 524 (1), pp. 135-141. Date of Electronic Publication: 2020 Jan 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement*
Gene Knockdown Techniques*
Entamoeba/*cytology
Entamoeba/*enzymology
Oxidoreductases/*metabolism
Trophozoites/*enzymology
Trophozoites/*growth & development
Cell Proliferation ; Cell Survival ; Down-Regulation/genetics ; Entamoeba/genetics ; Gene Amplification ; Life Cycle Stages ; Oxidoreductases/genetics ; Protein Transport ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Sphingomyelins/metabolism
Czasopismo naukowe
Tytuł :
Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro.
Autorzy :
Kohara Y; Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, 791-0295, Japan. Electronic address: .
Haraguchi R; Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, 791-0295, Japan.
Kitazawa R; Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, 791-0295, Japan; Division of Diagnostic Pathology, Ehime University Hospital, Shitsukawa, Toon City, Ehime, 791-0295, Japan.
Kitazawa S; Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, 791-0295, Japan.
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Mar 19; Vol. 523 (4), pp. 961-965. Date of Electronic Publication: 2020 Jan 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Communication*
Cell Differentiation*
Gene Knockdown Techniques*
Low Density Lipoprotein Receptor-Related Protein-1/*metabolism
Osteoblasts/*cytology
Osteoclasts/*cytology
Osteoclasts/*metabolism
Animals ; Cell Proliferation ; Mice ; Mice, Inbred C57BL ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
Rap2B knockdown suppresses malignant progression of hepatocellular carcinoma by inactivating the PTEN/PI3K/Akt and ERK1/2 pathways.
Autorzy :
Zhu L; Department of Pediatric Surgery, Henan Provincial People's Hospital, No.7, Wei Wu Road, Zhengzhou, 450003, Henan, People's Republic of China. .
Sun Y; Department of Clinical Laboratory, Third People's Hospital of Henan Province, Zhengzhou, Henan, People's Republic of China.
Zhang S; Department of Pediatric Surgery, Henan Provincial People's Hospital, No.7, Wei Wu Road, Zhengzhou, 450003, Henan, People's Republic of China.
Wang L; Department of Pediatric Surgery, Henan Provincial People's Hospital, No.7, Wei Wu Road, Zhengzhou, 450003, Henan, People's Republic of China.
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2020 Mar; Vol. 466 (1-2), pp. 55-63. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
MAP Kinase Signaling System*
Carcinoma, Hepatocellular/*metabolism
Liver Neoplasms/*metabolism
Mitogen-Activated Protein Kinase 1/*metabolism
Mitogen-Activated Protein Kinase 3/*metabolism
PTEN Phosphohydrolase/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
rab2 GTP-Binding Protein/*metabolism
Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Hep G2 Cells ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Mitogen-Activated Protein Kinase 1/genetics ; Mitogen-Activated Protein Kinase 3/genetics ; PTEN Phosphohydrolase/genetics ; Phosphatidylinositol 3-Kinases/genetics ; Proto-Oncogene Proteins c-akt ; rab2 GTP-Binding Protein/genetics
Czasopismo naukowe
Tytuł :
Stable Knockdown of Genes Encoding Extracellular Matrix Proteins in the C2C12 Myoblast Cell Line Using Small-Hairpin (sh)RNA.
Autorzy :
Taye N; Orthopaedic Research Laboratories, Leni & Peter W. May Department of Orthopaedics, Icahn School of Medicine at Mount Sinai.
Stanley S; Orthopaedic Research Laboratories, Leni & Peter W. May Department of Orthopaedics, Icahn School of Medicine at Mount Sinai.
Hubmacher D; Orthopaedic Research Laboratories, Leni & Peter W. May Department of Orthopaedics, Icahn School of Medicine at Mount Sinai; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 Feb 12 (156). Date of Electronic Publication: 2020 Feb 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Gene Knockdown Techniques*
ADAMTS Proteins/*genetics
Extracellular Matrix Proteins/*genetics
Myoblasts/*metabolism
RNA, Small Interfering/*genetics
ADAMTS Proteins/metabolism ; Animals ; Cell Differentiation ; Cell Line ; Extracellular Matrix Proteins/metabolism ; Mice ; Muscle Fibers, Skeletal/cytology ; Myoblasts/cytology ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Knockdown of Long Noncoding RNA (lncRNA) AK094457 Relieved Angiotensin II Induced Vascular Endothelial Cell Injury.
Autorzy :
Xu J; Department of Gerontology, Minhang Hospital, Fudan University, Shanghai, China (mainland).
Sun Y; Department of Critical Care Medicine, Minhang Hospital, Fudan University, Shanghai, China (mainland).
Lu J; Department of Gerontology, Minhang Hospital, Fudan University, Shanghai, China (mainland).
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Źródło :
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2020 Feb 06; Vol. 26, pp. e919854. Date of Electronic Publication: 2020 Feb 06.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
Endothelium, Vascular/*injuries
Endothelium, Vascular/*metabolism
RNA, Long Noncoding/*genetics
Adenylate Kinase/metabolism ; Angiotensin II ; Apoptosis ; Cell Adhesion Molecules/metabolism ; Cell Survival ; Endothelium, Vascular/pathology ; Human Umbilical Vein Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells/pathology ; Humans ; Inflammation Mediators/metabolism ; NADPH Oxidase 2/metabolism ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type III/metabolism ; Phosphorylation ; RNA, Long Noncoding/metabolism ; Reactive Oxygen Species/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Knockdown of Long Non-Coding RNA (lncRNA) Colon Cancer-Associated Transcript-1 (CCAT1) Suppresses Oral Squamous Cell Carcinoma Proliferation, Invasion, and Migration by Inhibiting the Discoidin Domain Receptor 2 (DDR2)/ERK/AKT Axis.
Autorzy :
Sun M; Department of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland).
Shen Z; Department of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland).
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Źródło :
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2020 Feb 03; Vol. 26, pp. e920020. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Knockdown Techniques*
MAP Kinase Signaling System*
Carcinoma, Squamous Cell/*genetics
Cell Movement/*genetics
Discoidin Domain Receptor 2/*metabolism
Mouth Neoplasms/*genetics
Proto-Oncogene Proteins c-akt/*metabolism
RNA, Long Noncoding/*genetics
Carcinoma, Squamous Cell/pathology ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Gene Silencing ; Humans ; Mouth Neoplasms/pathology ; Neoplasm Invasiveness ; Protein Binding ; RNA, Long Noncoding/metabolism ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Targeting exosome-associated human antigen R attenuates fibrosis and inflammation in diabetic heart.
Autorzy :
Govindappa PK; Department of Biomedical Engineering, Schools of Medicine and Engineering, The University of Alabama at Birmingham, AL, USA.
Patil M; Department of Biomedical Engineering, Schools of Medicine and Engineering, The University of Alabama at Birmingham, AL, USA.
Garikipati VNS; Center for Translational Medicine, Temple University School of Medicine, Philadelphia, PA, USA.
Verma SK; Division of Cardiovascular Disease, School of Medicine, University of Alabama at Birmingham, AL, USA.
Saheera S; Department of Biomedical Engineering, Schools of Medicine and Engineering, The University of Alabama at Birmingham, AL, USA.
Narasimhan G; Department of Biomedical Engineering, Schools of Medicine and Engineering, The University of Alabama at Birmingham, AL, USA.
Zhu W; Department of Biomedical Engineering, Schools of Medicine and Engineering, The University of Alabama at Birmingham, AL, USA.
Kishore R; Center for Translational Medicine, Temple University School of Medicine, Philadelphia, PA, USA.
Zhang J; Department of Biomedical Engineering, Schools of Medicine and Engineering, The University of Alabama at Birmingham, AL, USA.
Krishnamurthy P; Department of Biomedical Engineering, Schools of Medicine and Engineering, The University of Alabama at Birmingham, AL, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Feb; Vol. 34 (2), pp. 2238-2251. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Knockdown Techniques*
Diabetic Cardiomyopathies/*metabolism
ELAV-Like Protein 1/*metabolism
Macrophages/*metabolism
Myocardium/*metabolism
Animals ; Diabetic Cardiomyopathies/genetics ; Diabetic Cardiomyopathies/pathology ; Diabetic Cardiomyopathies/therapy ; ELAV-Like Protein 1/genetics ; Fibrosis ; Humans ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Macrophages/pathology ; Mice ; Mice, Transgenic ; Myocardium/pathology ; RAW 264.7 Cells
Czasopismo naukowe

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