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Wyszukujesz frazę ""Gene Knockdown Techniques"" wg kryterium: Temat


Tytuł:
Transcriptional Regulation Technology for Gene Perturbation in Fission Yeast.
Autorzy:
Ishikawa K; Department of Cell Biology, Institute of Life Science, Kurume University, Asahi-machi 67, Fukuoka 830-0011, Japan.
Saitoh S; Department of Cell Biology, Institute of Life Science, Kurume University, Asahi-machi 67, Fukuoka 830-0011, Japan.
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Źródło:
Biomolecules [Biomolecules] 2023 Apr 21; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcription, Genetic*
Schizosaccharomyces*/genetics
Gene Editing*/methods
CRISPR-Cas Systems*
Gene Knockdown Techniques*
Gene Expression Regulation, Fungal ; Mutation ; Genome-Wide Association Study
Czasopismo naukowe
Tytuł:
Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance.
Autorzy:
Pucci G; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
Minafra L; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
Bravatà V; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.
Calvaruso M; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.
Turturici G; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
Cammarata FP; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.
Savoca G; Radiation Oncology, ARNAS-Civico Hospital, 90100 Palermo, Italy.
Abbate B; Radiation Oncology, ARNAS-Civico Hospital, 90100 Palermo, Italy.
Russo G; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.
Cavalieri V; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
Forte GI; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 08; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/genetics
Glioblastoma*/radiotherapy
Glioblastoma*/metabolism
Glucose Transporter Type 3*/genetics
Glucose Transporter Type 3*/metabolism
Humans ; Biomarkers/metabolism ; Cell Hypoxia/genetics ; Cell Line, Tumor ; Gene Knockdown Techniques ; Hypoxia
Czasopismo naukowe
Tytuł:
Icariin promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by regulating USP47/SIRT1/Wnt/β-catenin.
Autorzy:
Wang H; Department of Orthopedics, First Affiliated Hospital of Naval Medical University, Shanghai, China.; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Zhang H; Department of Orthopedics, First Affiliated Hospital of Naval Medical University, Shanghai, China.
Zhang Y; Department of Orthopedics, First Affiliated Hospital of Naval Medical University, Shanghai, China.
Wang P; Department of Orthopedics, First Affiliated Hospital of Naval Medical University, Shanghai, China.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2024 Feb; Vol. 103 (2), pp. e14431.
Typ publikacji:
Journal Article
MeSH Terms:
Flavonoids*/pharmacology
Mesenchymal Stem Cells*/cytology
Mesenchymal Stem Cells*/drug effects
Mesenchymal Stem Cells*/metabolism
Osteogenesis*/drug effects
Osteogenesis*/genetics
Sirtuin 1*/genetics
Sirtuin 1*/metabolism
Humans ; beta Catenin/metabolism ; Cell Differentiation/drug effects ; Cells, Cultured ; Ubiquitin Thiolesterase/metabolism ; Ubiquitin-Specific Proteases/metabolism ; Gene Knockdown Techniques
Czasopismo naukowe
Tytuł:
A mobile CRISPRi collection enables genetic interaction studies for the essential genes of Escherichia coli.
Autorzy:
Rachwalski K; Institute of Infectious Disease Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
Tu MM; Institute of Infectious Disease Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
Madden SJ; Institute of Infectious Disease Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
French S; Institute of Infectious Disease Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
Hansen DM; Institute of Infectious Disease Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
Brown ED; Institute of Infectious Disease Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada. Electronic address: .
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Źródło:
Cell reports methods [Cell Rep Methods] 2024 Jan 22; Vol. 4 (1), pp. 100693.
Typ publikacji:
Journal Article
MeSH Terms:
Escherichia coli*
Genes, Essential*
Gene Editing ; Gene Knockdown Techniques ; Gene Library
Czasopismo naukowe
Tytuł:
ERH gene knockdown inhibits the proliferation and migration of ARPE-19 cells through MCM complex and EMT process.
Autorzy:
Li M; Department of Ophthalmology, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou, Jiangsu, China; Department of Ophthalmology, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou First People's Hospital, Eye Disease Prevention and Treatment Institute of Xuzhou, No. 269 Daxue Road, Xuzhou, Jiangsu, China. Electronic address: .
Zhang Z; Department of Ophthalmology, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou First People's Hospital, Eye Disease Prevention and Treatment Institute of Xuzhou, No. 269 Daxue Road, Xuzhou, Jiangsu, China. Electronic address: .
Guan L; Department of Ophthalmology, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou First People's Hospital, Eye Disease Prevention and Treatment Institute of Xuzhou, No. 269 Daxue Road, Xuzhou, Jiangsu, China. Electronic address: .
Ji S; Department of Ophthalmology, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou First People's Hospital, Eye Disease Prevention and Treatment Institute of Xuzhou, No. 269 Daxue Road, Xuzhou, Jiangsu, China. Electronic address: .
Lu P; Department of Ophthalmology, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou, Jiangsu, China. Electronic address: .
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Źródło:
Gene [Gene] 2024 Jan 20; Vol. 892, pp. 147855. Date of Electronic Publication: 2023 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*/genetics
Proteomics*
Cell Movement/genetics ; Gene Knockdown Techniques ; Cell Proliferation/genetics
Czasopismo naukowe
Tytuł:
Central 5-HTergic hyperactivity induces myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)-like pathophysiology.
Autorzy:
Lee JS; Research Center for CFS/ME, Daejeon Hospital of Daejeon University, Daejeon, Republic of Korea.; Institute of Bioscience & Integrative Medicine, Daejeon University, Daejeon, Republic of Korea.
Kang JY; Institute of Bioscience & Integrative Medicine, Daejeon University, Daejeon, Republic of Korea.
Park SY; Korean Medical College of Daejeon University, Daejeon, Republic of Korea.
Hwang SJ; Institute of Bioscience & Integrative Medicine, Daejeon University, Daejeon, Republic of Korea.
Bae SJ; College of Medicine, Kosin University, Busan, Republic of Korea.
Son CG; Research Center for CFS/ME, Daejeon Hospital of Daejeon University, Daejeon, Republic of Korea. .; Institute of Bioscience & Integrative Medicine, Daejeon University, Daejeon, Republic of Korea. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Jan 08; Vol. 22 (1), pp. 34. Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Fatigue Syndrome, Chronic*
Animals ; Mice ; Serotonin ; Disease Models, Animal ; Gene Knockdown Techniques ; Hypothalamo-Hypophyseal System
Czasopismo naukowe
Tytuł:
Inhibition of FoxO1 alleviates polycystic ovarian syndrome by reducing inflammation and the immune response.
Autorzy:
Huang X; Department of Reproductive Medicine, The Second Affiliated Hospital of Fujian Medical University, 34 North Zhongshan Road, Licheng District, Quanzhou, Fujian, China. .
Luo X; Department of Reproductive Medicine, The Second Affiliated Hospital of Fujian Medical University, 34 North Zhongshan Road, Licheng District, Quanzhou, Fujian, China.
Huang S; Department of Reproductive Medicine, The Second Affiliated Hospital of Fujian Medical University, 34 North Zhongshan Road, Licheng District, Quanzhou, Fujian, China.
Chen X; Department of Rheumatology, The Second Affiliated Hospital of Fujian Medical University, 34 North Zhongshan Road, Licheng District, Quanzhou, Fujian, China.
Qiu L; Department of Reproductive Medicine, The Second Affiliated Hospital of Fujian Medical University, 34 North Zhongshan Road, Licheng District, Quanzhou, Fujian, China.
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Źródło:
Functional & integrative genomics [Funct Integr Genomics] 2024 Jan 08; Vol. 24 (1), pp. 6. Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Polycystic Ovary Syndrome*/genetics
Forkhead Box Protein O1*/genetics
Animals ; Female ; Rats ; Immunity ; NF-kappa B ; NLR Family, Pyrin Domain-Containing 3 Protein ; Toll-Like Receptor 4 ; Gene Knockdown Techniques
Czasopismo naukowe
Tytuł:
Role and mechanism of miR-871-3p/Megf8 in regulating formaldehyde-induced cardiomyocyte inflammation and congenital heart disease.
Autorzy:
Yuan X; Department of Cardiac Ultrasound, The Affiliated Hospital of Qingdao University, Road No. 59 Haier, Qingdao 266100, Shandong Province, People's Republic of China.
Chen R; Heart Center, Women and Children's Hospital, Qingdao University, Qingdao 266034, Shandong Province, People's Republic of China.
Luo G; Heart Center, Women and Children's Hospital, Qingdao University, Qingdao 266034, Shandong Province, People's Republic of China.
Sun P; Department of Cardiac Ultrasound, The Affiliated Hospital of Qingdao University, Road No. 59 Haier, Qingdao 266100, Shandong Province, People's Republic of China.
Song X; Department of Cardiac Ultrasound, The Affiliated Hospital of Qingdao University, Road No. 59 Haier, Qingdao 266100, Shandong Province, People's Republic of China.
Ma J; Department of Cardiac Ultrasound, The Affiliated Hospital of Qingdao University, Road No. 59 Haier, Qingdao 266100, Shandong Province, People's Republic of China.
Sun R; Department of Cardiac Ultrasound, The Affiliated Hospital of Qingdao University, Road No. 59 Haier, Qingdao 266100, Shandong Province, People's Republic of China.
Yu T; Department of Cardiac Ultrasound, The Affiliated Hospital of Qingdao University, Road No. 59 Haier, Qingdao 266100, Shandong Province, People's Republic of China; Institute for Translational Medicine, The Affiliated Hospital of Qingdao University, No. 38 Dengzhou Road, Qingdao 266021, Shandong Province, People's Republic of China. Electronic address: .
Jiang Z; Department of Cardiac Ultrasound, The Affiliated Hospital of Qingdao University, Road No. 59 Haier, Qingdao 266100, Shandong Province, People's Republic of China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2024 Jan 05; Vol. 126, pp. 111297. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Formaldehyde*/metabolism
Formaldehyde*/toxicity
Heart Diseases*/congenital
Heart Diseases*/metabolism
Heart Diseases*/pathology
Membrane Proteins*/metabolism
Animals ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Rats ; Air Pollutants/metabolism ; Air Pollutants/toxicity ; Disease Models, Animal ; Gene Expression ; Gene Knockdown Techniques ; Heart/drug effects ; Heart/physiopathology ; Inflammation/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions.
Autorzy:
W-M Fan T; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA. Electronic address: .
Islam JMM; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA.
Higashi RM; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.
Lin P; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.
Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.
Lane AN; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105485. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Enhancer of Zeste Homolog 2 Protein*/genetics
Enhancer of Zeste Homolog 2 Protein*/metabolism
Metabolic Reprogramming*/genetics
Humans ; Cell Line, Tumor ; Polycomb Repressive Complex 2/antagonists & inhibitors ; Polycomb Repressive Complex 2/genetics ; A549 Cells ; Adenocarcinoma of Lung/physiopathology ; Gene Knockdown Techniques ; Glycolysis/genetics ; Citric Acid Cycle/genetics ; Pentose Phosphate Pathway/genetics ; Purine Nucleotides/genetics ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Tytuł:
TET1-mediated epigenetic regulation of tumor necrosis factor-α in trigeminal ganglia contributes to chronic temporomandibular joint pain.
Autorzy:
Wang Z; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Ma H; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Nasir A; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Medical Research Center, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Liu S; Department of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX, USA.
Li Z; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Tao F; Department of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX, USA. Electronic address: .
Bai Q; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China; Medical Research Center, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2024 Jan 01; Vol. 336, pp. 122283. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Necrosis Factor-alpha*/genetics
Tumor Necrosis Factor-alpha*/metabolism
DNA-Binding Proteins*/metabolism
Trigeminal Ganglion*/physiopathology
Arthralgia*/chemically induced
Arthralgia*/physiopathology
Temporomandibular Joint*/physiopathology
Epigenesis, Genetic/genetics ; Male ; Animals ; Mice ; Mice, Inbred C57BL ; Freund's Adjuvant/pharmacology ; Up-Regulation/drug effects ; Neurons/metabolism ; Gene Knockdown Techniques ; Promoter Regions, Genetic ; Protein Binding/drug effects
Czasopismo naukowe
Tytuł:
Multi-lipase gene knockdown in Chinese hamster ovary cells using artificial microRNAs to reduce host cell protein mediated polysorbate degradation.
Autorzy:
Weiß L; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
Schmieder-Todtenhaupt V; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
Haemmerling F; Early Stage Pharmaceutical Development, Pharmaceutical Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
Lakatos D; Late Stage DSP, Bioprocess Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
Schulz P; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
Fischer S; Cell Line Development, Bioprocess Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
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Źródło:
Biotechnology and bioengineering [Biotechnol Bioeng] 2024 Jan; Vol. 121 (1), pp. 329-340. Date of Electronic Publication: 2023 Sep 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MicroRNAs*/genetics
Cricetinae ; Animals ; Humans ; Cricetulus ; CHO Cells ; Polysorbates ; Lipase ; Gene Knockdown Techniques
Czasopismo naukowe
Tytuł:
UV-LASER adjuvant-surfactant-facilitated delivery of mobile dsRNA to tomato plant vasculature and evidence of biological activity by gene knockdown in the potato psyllid.
Autorzy:
Thakre N; School of Plant Sciences, The University of Arizona, Tucson, AZ, USA.; Division of Biological Sciences, Section of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, USA.
Carver M; School of Plant Sciences, The University of Arizona, Tucson, AZ, USA.
Paredes-Montero JR; Biology Department, Saginaw Valley State University, University Center, USA.; Facultad de Ciencias de la Vida, Escuela Superior Politécnica del Litoral, ESPOL, Campus Gustavo Galindo, Guayaquil, Ecuador.
Mondal M; School of Plant Sciences, The University of Arizona, Tucson, AZ, USA.
Hu J; School of Plant Sciences, The University of Arizona, Tucson, AZ, USA.
Saberi E; Department of Entomology and Nematology, IFAS, Southwest Florida Research and Education Center, University of Florida, Immokalee, FL, USA.
Ponvert N; School of Plant Sciences, The University of Arizona, Tucson, AZ, USA.
Qureshi JA; Department of Entomology and Nematology, IFAS, Southwest Florida Research and Education Center, University of Florida, Immokalee, FL, USA.
Brown JK; School of Plant Sciences, The University of Arizona, Tucson, AZ, USA.
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Źródło:
Pest management science [Pest Manag Sci] 2024 Apr; Vol. 80 (4), pp. 2141-2153. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Solanum lycopersicum*/genetics
Hemiptera*/metabolism
Animals ; RNA, Double-Stranded/genetics ; RNA Interference ; Surface-Active Agents/pharmacology ; Gene Knockdown Techniques ; Gelsolin/genetics ; Gelsolin/metabolism ; Ultraviolet Rays ; Lasers ; Plant Diseases/microbiology
Czasopismo naukowe
Tytuł:
Magnetic graphene oxide nanoflakes for dual RNA interfering delivery and gene knockdown in prostate and liver cancers.
Autorzy:
Liu CH; Department of Chemical and Materials Engineering, Chang Gung University, 259, Wen-Hwa First Road, Tao-Yuan, Taiwan; Research Center for Chinese Herbal Medicine and Research Center for Food and Cosmetic Safety, College of Human Ecology, Chang Gung University of Science and Technology, 261, Wen-Hwa First Road, Taoyuan, Taiwan; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, 5, Fu-Hsing Street, Taoyuan, Taiwan. Electronic address: .
Chen YJ; Department of Chemical and Materials Engineering, Chang Gung University, 259, Wen-Hwa First Road, Tao-Yuan, Taiwan.
Wu WC; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, 5, Fu-Hsing Street, Taoyuan, Taiwan; College of Medicine, Chang Gung University, 259, Wen-Hwa First Road, Taoyuan, Taiwan.
Lin YH; Department of Chemical and Biological Engineering, University of Saskatchewan, Saskatoon, SK, Canada.
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 8), pp. 127357. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*
Liver Neoplasms*/genetics
Male ; Humans ; Gene Knockdown Techniques ; Prostate ; RNA, Small Interfering/genetics ; Magnetic Phenomena ; Polyethyleneimine
Czasopismo naukowe
Tytuł:
CPEB2 inhibit cell proliferation through upregulating p21 mRNA stability in glioma.
Autorzy:
Zhao G; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221000, Jiangsu, China.; Department of Emergency Medicine, The First People's Hospital of Kunshan, Kunshan, 215300, Jiangsu, China.
Zhao Z; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Xia M; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Xiao L; Department of Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, China.
Zhu B; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Wang H; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China.
Li X; Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221000, Jiangsu, China. .
Di J; Cancer Institute, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China. .; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221002, Jiangsu, China. .; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221004, Jiangsu, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 29; Vol. 13 (1), pp. 23103. Date of Electronic Publication: 2023 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
RNA-Binding Proteins*/blood
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Oncogene Protein p21(ras)*/genetics
Oncogene Protein p21(ras)*/metabolism
RNA Stability*/genetics
Glioma*/diagnosis
Glioma*/physiopathology
Gene Expression Regulation, Neoplastic*/genetics
Cell Proliferation/genetics ; Gene Knockdown Techniques ; Apoptosis/genetics ; Cell Cycle Checkpoints/genetics ; Biomarkers, Tumor/blood ; Down-Regulation/genetics ; Cell Line, Tumor ; Mice, Inbred BALB C ; HEK293 Cells ; Humans ; Female ; Animals ; Mice
Czasopismo naukowe
Tytuł:
Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance.
Autorzy:
Socodato R; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal. Electronic address: .
Almeida TO; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal; ICBAS - School of Medicine and Biomedical Sciences, Porto, Portugal.
Portugal CC; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal.
Santos ECS; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal; Department of Biomedicine, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal.
Tedim-Moreira J; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal; Department of Biomedicine, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal.
Galvão-Ferreira J; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal; Department of Biomedicine, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal.
Canedo T; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal.
Baptista FI; Center for Innovative Biomedicine and Biotechnology (CIBB), Coimbra Institute for Clinical and Biomedical Research (iCBR), and Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.
Magalhães A; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal.
Ambrósio AF; Center for Innovative Biomedicine and Biotechnology (CIBB), Coimbra Institute for Clinical and Biomedical Research (iCBR), and Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.
Brakebusch C; Molecular Pathology Section, BRIC, Københavns Biocenter, Copenhagen, Denmark.
Rubinstein B; Stowers Institute for Medical Research, Kansas City, MO, USA.
Moreira IS; Department of Life Sciences, Center for Innovative Biomedicine and Biotechnology (CIBB) and CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Summavielle T; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal; ESS.PP, Escola Superior de Saúde do Politécnico do Porto, Porto, Portugal.
Pinto IM; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal; Department of Biomedicine, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal.
Relvas JB; Institute of Research and Innovation in Health (i3S) and Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal; Department of Biomedicine, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2023 Dec 26; Vol. 42 (12), pp. 113447. Date of Electronic Publication: 2023 Nov 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microglia*/metabolism
Neuronal Plasticity*
Cognition*/physiology
Neuropeptides*/genetics
Neuropeptides*/physiology
rac1 GTP-Binding Protein*/genetics
rac1 GTP-Binding Protein*/physiology
Brain*/physiology
Animals ; Mice ; Male ; Female ; Mice, Mutant Strains ; Synapses/physiology ; Gene Knockdown Techniques
Czasopismo naukowe
Tytuł:
Quantification of cell energetics in human subcutaneous adipose progenitor cells after target gene knockdown.
Autorzy:
Li L; University of California San Francisco, San Francisco, CA 94158, USA. Electronic address: .
Gunewardena AM; University of California San Francisco, San Francisco, CA 94158, USA.
Nyima T; University of California San Francisco, San Francisco, CA 94158, USA.
Feldman BJ; University of California San Francisco, San Francisco, CA 94158, USA. Electronic address: .
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Źródło:
STAR protocols [STAR Protoc] 2023 Dec 15; Vol. 4 (4), pp. 102607. Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:
Journal Article
MeSH Terms:
Adipocytes*
Adipose Tissue*
Humans ; Gene Knockdown Techniques ; Cell Differentiation/genetics ; Stem Cells
Czasopismo naukowe
Tytuł:
Impact of Peptide Sequence on Functional siRNA Delivery and Gene Knockdown with Cyclic Amphipathic Peptide Delivery Agents.
Autorzy:
Jagrosse ML; Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, United States.
Baliga UK; Department of Pediatrics and Neonatology, University of Rochester Medical Center, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, United States.
Jones CW; Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, United States.
Russell JJ; Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, United States.
García CI; Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, United States.
Najar RA; Department of Pediatrics and Neonatology, University of Rochester Medical Center, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, United States.
Rahman A; Department of Pediatrics and Neonatology, University of Rochester Medical Center, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, United States.
Dean DA; Department of Pediatrics and Neonatology, University of Rochester Medical Center, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, United States.
Nilsson BL; Department of Chemistry, University of Rochester, Rochester, New York 14627-0216, United States.; Materials Science Program, University of Rochester, Rochester, New York 14627, United States.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2023 Dec 04; Vol. 20 (12), pp. 6090-6103. Date of Electronic Publication: 2023 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Peptides, Cyclic*/chemistry
Cell-Penetrating Peptides*/chemistry
RNA, Small Interfering/chemistry ; Gene Knockdown Techniques ; Oligonucleotides ; Disulfides
Czasopismo naukowe
Tytuł:
FOXE1 Contributes to the Development of Psoriasis by Regulating WNT5A.
Autorzy:
Liu M; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhang G; Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Wang Z; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Liu X; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
He K; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Luo R; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Duan Q; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Bai R; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang Y; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Du W; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zheng Y; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. Electronic address: .
Shao Y; Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China; Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. Electronic address: .
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Źródło:
The Journal of investigative dermatology [J Invest Dermatol] 2023 Dec; Vol. 143 (12), pp. 2366-2377.e7. Date of Electronic Publication: 2023 Jun 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Psoriasis*/metabolism
Psoriasis*/pathology
Forkhead Transcription Factors*/genetics
Forkhead Transcription Factors*/metabolism
Wnt-5a Protein*/metabolism
Humans ; Cell Proliferation ; Keratinocytes/metabolism ; Interleukin-6/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Gene Knockdown Techniques ; Animals ; Mice ; Vascular Endothelial Growth Factor A/metabolism ; Male ; Female ; Child ; Adolescent ; Adult
Czasopismo naukowe
Tytuł:
The knockdown of lncRNA DLGAP1-AS2 suppresses osteosarcoma progression by inhibiting aerobic glycolysis via the miR-451a/HK2 axis.
Autorzy:
Zheng C; Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Li R; Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Zheng S; Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Fang H; Department of Electric Diagnostic, The Fourth Hospital of Jilin University, Changchun, China.
Xu M; Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Zhong L; Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
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Źródło:
Cancer science [Cancer Sci] 2023 Dec; Vol. 114 (12), pp. 4747-4762. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Osteosarcoma*/genetics
Osteosarcoma*/physiopathology
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Warburg Effect, Oncologic*
Humans ; Cell Line, Tumor ; Disease Progression ; Gene Expression Regulation, Neoplastic/genetics ; Gene Knockdown Techniques ; Hexokinase/metabolism ; Mice, Inbred BALB C ; MicroRNAs/metabolism
Czasopismo naukowe
Tytuł:
An AMPK agonist suppresses the progress of colorectal cancer by regulating the polarization of TAM to M1 through inhibition of HIF-1α and mTOR signal pathway.
Autorzy:
Cao Y; Department of Laboratory Medicine, Hangzhou Cancer Hospital, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Shangcheng, China.
Wo M; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Xu C; Department of Laboratory Medicine, Affiliated Third Hospital of Zhejiang Traditional Chinese Medicine University, Xihu, Hangzhou, Zhejiang, China.
Fei X; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Jin J; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
Shan Z; Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Zhejiang Center for Clinical Laboratory, Gongshu, China.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Dec 01; Vol. 19 (6), pp. 1560-1567. Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Metformin*/pharmacology
Metformin*/therapeutic use
Signal Transduction*/drug effects
TOR Serine-Threonine Kinases*/antagonists & inhibitors
TOR Serine-Threonine Kinases*/metabolism
Colorectal Neoplasms*/drug therapy
Tumor-Associated Macrophages*/drug effects
Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; HCT116 Cells ; Cell Polarity/drug effects ; THP-1 Cells ; AMP-Activated Protein Kinases/antagonists & inhibitors ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; Gene Knockdown Techniques
Czasopismo naukowe

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