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Wyszukujesz frazę ""Gene Transfer Techniques"" wg kryterium: Temat


Tytuł :
Mineralized polyplexes for gene delivery: Improvement of transfection efficiency as a consequence of calcium incubation and not mineralization.
Autorzy :
A Dick T; Department of Chemical and Materials Engineering, Faculty of Engineering, University of Alberta, Edmonton, AB, Canada. Electronic address: .
Uludağ H; Department of Chemical and Materials Engineering, Faculty of Engineering, University of Alberta, Edmonton, AB, Canada; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada; Department of Biomedical Engineering, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2021 Oct; Vol. 129, pp. 112419. Date of Electronic Publication: 2021 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium*
Gene Transfer Techniques*
Animals ; Genetic Therapy ; Mice ; Plasmids/genetics ; Transfection
Czasopismo naukowe
Tytuł :
Transfer of miRNA in tumor-derived exosomes suppresses breast tumor cell invasion and migration by inducing M1 polarization in macrophages.
Autorzy :
Moradi-Chaleshtori M; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shojaei S; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammadi-Yeganeh S; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Hashemi SM; Medical Nanotechnology and Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 01; Vol. 282, pp. 119800. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
Genetic Therapy*
Macrophage Activation*
Breast Neoplasms/*therapy
Exosomes/*genetics
MicroRNAs/*therapeutic use
Animals ; Breast Neoplasms/genetics ; Breast Neoplasms/immunology ; Cell Proliferation ; Female ; Mice ; Mice, Inbred C57BL ; MicroRNAs/administration & dosage ; MicroRNAs/genetics ; Phagocytosis ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Anti-TGFβ (Transforming Growth Factor β) Therapy With Betaglycan-Derived P144 Peptide Gene Delivery Prevents the Formation of Aortic Aneurysm in a Mouse Model of Marfan Syndrome.
Autorzy :
Arce C; Department of Biomedical Sciences, School of Medicine and Health Sciences, University of Barcelona, Spain (C.A., I.R.-R., K.D.R., V.C., G.E.).
Rodríguez-Rovira I; Department of Biomedical Sciences, School of Medicine and Health Sciences, University of Barcelona, Spain (C.A., I.R.-R., K.D.R., V.C., G.E.).
De Rycke K; Department of Biomedical Sciences, School of Medicine and Health Sciences, University of Barcelona, Spain (C.A., I.R.-R., K.D.R., V.C., G.E.).
Durán K; Department of Cardiology, Hospital Clínic y Provincial de Barcelona, Spain (K.D.).
Campuzano V; Department of Biomedical Sciences, School of Medicine and Health Sciences, University of Barcelona, Spain (C.A., I.R.-R., K.D.R., V.C., G.E.).; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), ISCIII, Spain (V.C.).
Fabregat I; Bellvitge Biomedical Research Institute (IDIBELL) and Centro de Investigación Biomédica en Red de Enfermedades Hepático-Digestivas (CIBEREHD), ISCIII, Spain (I.F.).
Jiménez-Altayó F; Department of Therapeutic Pharmacology and Toxicology, School of Medicine, Neuroscience Institute, Autonomous University of Barcelona, Bellaterra, Spain (F.J.-A.).
Berraondo P; Program of Immunology and Immunotherapy, CIMA University of Navarra, Pamplona, Spain (P.B.).; Navarra Institute for Health Research (IDISNA), Pamplona, Spain (P.B.).
Egea G; Department of Biomedical Sciences, School of Medicine and Health Sciences, University of Barcelona, Spain (C.A., I.R.-R., K.D.R., V.C., G.E.).; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain (G.E.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Sep; Vol. 41 (9), pp. e440-e452. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Transfer Techniques*
Genetic Therapy*
Aorta/*metabolism
Aortic Aneurysm/*prevention & control
Marfan Syndrome/*complications
Peptide Fragments/*metabolism
Proteoglycans/*metabolism
Receptors, Transforming Growth Factor beta/*metabolism
Transforming Growth Factor beta/*metabolism
Animals ; Aorta/pathology ; Aortic Aneurysm/genetics ; Aortic Aneurysm/metabolism ; Aortic Aneurysm/pathology ; Dependovirus/genetics ; Dilatation, Pathologic ; Disease Models, Animal ; Female ; Fibrillin-1/genetics ; Genetic Vectors ; Male ; Marfan Syndrome/genetics ; Mice, Inbred C57BL ; Peptide Fragments/genetics ; Proteoglycans/genetics ; Receptors, Transforming Growth Factor beta/genetics ; Signal Transduction ; Transforming Growth Factor beta/genetics
Czasopismo naukowe
Tytuł :
An advanced method for the small-scale production of high-quality minicircle DNA.
Autorzy :
Mitdank H; Institute of Pharmacy, Free University of Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany. Electronic address: .
Sama S; Institute of Pharmacy, Free University of Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany.
Tröger M; Institute of Pharmacy, Free University of Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany.
Testa MF; Department of Life Sciences and Biotechnologies, University of Ferrara, Via Luigi Borsari 64, 44121 Ferrara, Italy.
Ferrarese M; Department of Life Sciences and Biotechnologies, University of Ferrara, Via Luigi Borsari 64, 44121 Ferrara, Italy.
Balestra D; Department of Life Sciences and Biotechnologies, University of Ferrara, Via Luigi Borsari 64, 44121 Ferrara, Italy.
Pinotti M; Department of Life Sciences and Biotechnologies, University of Ferrara, Via Luigi Borsari 64, 44121 Ferrara, Italy.
Weng A; Institute of Pharmacy, Free University of Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Aug 10; Vol. 605, pp. 120830. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
Genetic Vectors*
DNA ; Humans ; Plasmids ; Transfection
Czasopismo naukowe
Tytuł :
The Ocular Gene Delivery Landscape.
Autorzy :
Sahu B; Department of Ophthalmology & Visual Sciences, UMass Medical School, Worcester, MA 01655, USA.
Chug I; Department of Ophthalmology & Visual Sciences, UMass Medical School, Worcester, MA 01655, USA.
Khanna H; Department of Ophthalmology & Visual Sciences, UMass Medical School, Worcester, MA 01655, USA.
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Źródło :
Biomolecules [Biomolecules] 2021 Aug 01; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Gene Transfer Techniques*
Eye Diseases/*therapy
Genetic Therapy/*methods
Genetic Vectors/*metabolism
Animals ; Choroidal Effusions ; DNA/genetics ; DNA/metabolism ; DNA/therapeutic use ; Eye/metabolism ; Eye/pathology ; Eye Diseases/genetics ; Eye Diseases/metabolism ; Eye Diseases/pathology ; Genetic Vectors/administration & dosage ; Genetic Vectors/chemistry ; Humans ; Intravitreal Injections ; Liposomes/chemistry ; Liposomes/metabolism ; Liposomes/therapeutic use ; Nanoparticles/administration & dosage ; Nanoparticles/chemistry ; Nanoparticles/metabolism ; Peptides/chemistry ; Peptides/metabolism ; Peptides/therapeutic use ; Subretinal Fluid ; Viruses/genetics ; Viruses/metabolism ; Vitreous Body
Czasopismo naukowe
Tytuł :
Gene electrotransfer of proinflammatory chemokines CCL5 and CCL17 as a novel approach of modifying cytokine expression profile in the tumor microenvironment.
Autorzy :
Bozic T; Department of Experimental Oncology, Institute of Oncology Ljubljana, Zaloska cesta 2, SI-1000 Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Vrazov trg 2, SI-1000 Ljubljana, Slovenia.
Sersa G; Department of Experimental Oncology, Institute of Oncology Ljubljana, Zaloska cesta 2, SI-1000 Ljubljana, Slovenia; Faculty of Health Sciences, University of Ljubljana, Zdravstvena pot 5, SI-1000 Ljubljana, Slovenia.
Kranjc Brezar S; Department of Experimental Oncology, Institute of Oncology Ljubljana, Zaloska cesta 2, SI-1000 Ljubljana, Slovenia.
Cemazar M; Department of Experimental Oncology, Institute of Oncology Ljubljana, Zaloska cesta 2, SI-1000 Ljubljana, Slovenia; Faculty of Health Sciences, University of Primorska, Polje 42, SI-6310 Izola, Slovenia. Electronic address: .
Markelc B; Department of Experimental Oncology, Institute of Oncology Ljubljana, Zaloska cesta 2, SI-1000 Ljubljana, Slovenia; Faculty of Health Sciences, University of Ljubljana, Zdravstvena pot 5, SI-1000 Ljubljana, Slovenia. Electronic address: .
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Źródło :
Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2021 Aug; Vol. 140, pp. 107795. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
Tumor Microenvironment*
Chemokine CCL17/*genetics
Chemokine CCL5/*genetics
Neoplasms/*genetics
Animals ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Genetic Therapy ; Mice ; Mice, Inbred BALB C ; Neoplasms/therapy ; Transcriptome
Czasopismo naukowe
Tytuł :
Growth environment influences B16.F10 mouse melanoma cell response to gene electrotransfer.
Autorzy :
Heller L; Department of Medical Engineering, University of South Florida, Tampa, FL, USA. Electronic address: .
Bulysheva A; Department of Electrical & Computer Engineering, Old Dominion University, Norfolk, VA, USA.
Arpag S; Department of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA, USA.
Sales Conniff A; Department of Medical Engineering, University of South Florida, Tampa, FL, USA.
Kohena K; Department of Medical Engineering, University of South Florida, Tampa, FL, USA.
Shi G; Department of Medical Engineering, University of South Florida, Tampa, FL, USA.
Semenova N; Center for Bioelectrics, Old Dominion University, Norfolk, VA, USA.
Heller R; Department of Medical Engineering, University of South Florida, Tampa, FL, USA.
Cemazar M; Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia; Faculty of Health Sciences, University of Primorska, Izola, Slovenia. Electronic address: .
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Źródło :
Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2021 Aug; Vol. 140, pp. 107827. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Electroporation*
Gene Transfer Techniques*
Melanoma, Experimental/*pathology
Animals ; Mice ; Plasmids/genetics ; Transfection
Czasopismo naukowe
Tytuł :
Monopolar gene electrotransfer enhances plasmid DNA delivery to skin.
Autorzy :
Bulysheva A; Department of Electrical and Computer Engineering, Old Dominion University, Norfolk VA, United States. Electronic address: .
Heller L; Department of Medical Engineering, University of South Florida, Tampa, FL, United States.
Francis M; Embody Inc., Norfolk, VA, United States.
Varghese F; Department of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA, United States.
Boye C; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, United States.
Heller R; Department of Medical Engineering, University of South Florida, Tampa, FL, United States.
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Źródło :
Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2021 Aug; Vol. 140, pp. 107814. Date of Electronic Publication: 2021 Apr 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*/instrumentation
DNA/*genetics
DNA/*metabolism
Plasmids/*genetics
Skin/*metabolism
Animals ; Electrodes ; Electroporation ; Guinea Pigs
Czasopismo naukowe
Tytuł :
A review of the tortuous path of nonviral gene delivery and recent progress.
Autorzy :
Sharma D; Department of Pharmaceutical Sciences, School of Pharmacy, College of Health Professions, North Dakota State University, Fargo 58105, ND, USA.
Arora S; Department of Pharmaceutical Sciences, School of Pharmacy, College of Health Professions, North Dakota State University, Fargo 58105, ND, USA.
Singh J; Department of Pharmaceutical Sciences, School of Pharmacy, College of Health Professions, North Dakota State University, Fargo 58105, ND, USA.
Layek B; Department of Pharmaceutical Sciences, School of Pharmacy, College of Health Professions, North Dakota State University, Fargo 58105, ND, USA. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 31; Vol. 183, pp. 2055-2073. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Transfer Techniques*/adverse effects
Genetic Therapy*/adverse effects
Lipids/*chemistry
Polymers/*chemistry
Animals ; COVID-19 Vaccines/genetics ; COVID-19 Vaccines/therapeutic use ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/therapeutic use
Czasopismo naukowe
Tytuł :
Generation of Recombinant Primary Human B Lymphocytes Using Non-Viral Vectors.
Autorzy :
Keim D; Process Biotechnology, University of Bayreuth, 95447 Bayreuth, Germany.
Gollner K; Praxis am Schießgraben, Schießgraben 21, 95326 Kulmbach, Germany.
Gollner U; Praxis am Schießgraben, Schießgraben 21, 95326 Kulmbach, Germany.
Jérôme V; Process Biotechnology, University of Bayreuth, 95447 Bayreuth, Germany.
Freitag R; Process Biotechnology, University of Bayreuth, 95447 Bayreuth, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 30; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
B-Lymphocytes/*metabolism
Genetic Vectors/*genetics
B-Lymphocytes/cytology ; Cells, Cultured ; Humans ; Methacrylates/chemistry ; Nylons/chemistry ; Transgenes
Czasopismo naukowe
Tytuł :
Bacterium-mimicking sequentially targeted therapeutic nanocomplexes based on O-carboxymethyl chitosan and their cooperative therapy by dual-modality light manipulation.
Autorzy :
Zhou J; Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610041, PR China.
Ma S; Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610041, PR China.
Zhang Y; Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610041, PR China.
He Y; Research Institute for Biomaterials, Tech Institute for Advanced Materials, College of Materials Science and Engineering, Suqian Advanced Materials Industry Technology Innovation Center, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Nanjing Tech University, 30 South Puzhu Road, Nanjing, 211816, PR China. Electronic address: .
Mao H; Research Institute for Biomaterials, Tech Institute for Advanced Materials, College of Materials Science and Engineering, Suqian Advanced Materials Industry Technology Innovation Center, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Nanjing Tech University, 30 South Puzhu Road, Nanjing, 211816, PR China.
Yang J; The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science, Nankai University, Tianjin, 300071, PR China.
Zhang H; Amgen Bioprocessing Centre, Keck Graduate Institute, Claremont, CA, 91711, USA.
Luo K; Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610041, PR China.
Gong Q; Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610041, PR China.
Gu Z; Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610041, PR China; Research Institute for Biomaterials, Tech Institute for Advanced Materials, College of Materials Science and Engineering, Suqian Advanced Materials Industry Technology Innovation Center, NJTech-BARTY Joint Research Center for Innovative Medical Technology, Nanjing Tech University, 30 South Puzhu Road, Nanjing, 211816, PR China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Jul 15; Vol. 264, pp. 118030. Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
Biomimetic Materials/*chemistry
Chitosan/*analogs & derivatives
Nanoparticles/*chemistry
Photochemotherapy/*methods
A549 Cells ; Animals ; Apoptosis ; Bacteria/chemistry ; Biomimetics/methods ; Cell Line, Tumor ; Chitosan/chemistry ; DNA/metabolism ; Endocytosis ; Human Umbilical Vein Endothelial Cells ; Humans ; Light ; Lysosomes/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
How Far Are Non-Viral Vectors to Come of Age and Reach Clinical Translation in Gene Therapy?
Autorzy :
Sainz-Ramos M; NanoBioCel Group, Faculty of Pharmacy, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.; Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.; Bioaraba, NanoBioCel Resarch Group, 01009 Vitoria-Gasteiz, Spain.
Gallego I; NanoBioCel Group, Faculty of Pharmacy, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.; Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.; Bioaraba, NanoBioCel Resarch Group, 01009 Vitoria-Gasteiz, Spain.
Villate-Beitia I; NanoBioCel Group, Faculty of Pharmacy, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.; Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.; Bioaraba, NanoBioCel Resarch Group, 01009 Vitoria-Gasteiz, Spain.
Zarate J; NanoBioCel Group, Faculty of Pharmacy, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.; Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.; Bioaraba, NanoBioCel Resarch Group, 01009 Vitoria-Gasteiz, Spain.
Maldonado I; NanoBioCel Group, Faculty of Pharmacy, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.
Puras G; NanoBioCel Group, Faculty of Pharmacy, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.; Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.; Bioaraba, NanoBioCel Resarch Group, 01009 Vitoria-Gasteiz, Spain.
Pedraz JL; NanoBioCel Group, Faculty of Pharmacy, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain.; Networking Research Centre of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 28029 Madrid, Spain.; Bioaraba, NanoBioCel Resarch Group, 01009 Vitoria-Gasteiz, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 14; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Transfer Techniques*
Genetic Diseases, Inborn/*therapy
Genetic Therapy/*methods
Genetic Vectors/*administration & dosage
Nanoparticles/*administration & dosage
Animals ; Genetic Diseases, Inborn/genetics ; Genetic Vectors/genetics ; Humans
Czasopismo naukowe
Tytuł :
Gene therapy for aromatic L-amino acid decarboxylase deficiency by MR-guided direct delivery of AAV2-AADC to midbrain dopaminergic neurons.
Autorzy :
Pearson TS; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Gupta N; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
San Sebastian W; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Imamura-Ching J; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Viehoever A; Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Grijalvo-Perez A; Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Fay AJ; Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Seth N; Department of Rehabilitative Services, University of California San Francisco, San Francisco, CA, USA.
Lundy SM; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Seo Y; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Pampaloni M; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Hyland K; Medical Neurogenetics Laboratories, Atlanta, GA, USA.
Smith E; Therapy Services, St. Louis Children's Hospital, St. Louis, MO, USA.
de Oliveira Barbosa G; School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH, USA.
Heathcock JC; School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH, USA.
Minnema A; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.
Lonser R; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.
Elder JB; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.
Leonard J; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA.; Department of Neurological Surgery, Nationwide Children's Hospital, Columbus, OH, USA.
Larson P; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Bankiewicz KS; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA. .; Department of Neurological Surgery, The Ohio State University, Columbus, OH, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 12; Vol. 12 (1), pp. 4251. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Transfer Techniques*
Genetic Therapy*/adverse effects
Magnetic Resonance Imaging*
Amino Acid Metabolism, Inborn Errors/*genetics
Amino Acid Metabolism, Inborn Errors/*therapy
Aromatic-L-Amino-Acid Decarboxylases/*deficiency
Dependovirus/*genetics
Dopaminergic Neurons/*metabolism
Mesencephalon/*pathology
Amino Acid Metabolism, Inborn Errors/cerebrospinal fluid ; Amino Acid Metabolism, Inborn Errors/physiopathology ; Aromatic-L-Amino-Acid Decarboxylases/cerebrospinal fluid ; Aromatic-L-Amino-Acid Decarboxylases/genetics ; Child ; Child, Preschool ; Dyskinesias/physiopathology ; Female ; Humans ; Male ; Metabolome ; Motor Activity ; Neurotransmitter Agents/cerebrospinal fluid ; Neurotransmitter Agents/metabolism ; Time Factors
SCR Disease Name :
Aromatic amino acid decarboxylase deficiency
Czasopismo naukowe
Tytuł :
A Two-Pronged Pulmonary Gene Delivery Strategy: A Surface-Modified Fullerene Nanoparticle and a Hypotonic Vehicle.
Autorzy :
Chen D; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University, Baltimore, MD, USA.
Liu S; Key Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun North First Street 2, Beijing, PR China.
Chen D; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
Liu J; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
Wu J; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.
Wang H; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
Su Y; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University, Baltimore, MD, USA.
Kwak G; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University, Baltimore, MD, USA.
Zuo X; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
Rao D; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
Cui H; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
Shu C; Key Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun North First Street 2, Beijing, PR China.
Suk JS; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Johns Hopkins, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Jul 05; Vol. 60 (28), pp. 15225-15229. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Transfer Techniques*
Epoxy Compounds/*chemistry
Fullerenes/*chemistry
Lung Diseases/*therapy
Nanoparticles/*chemistry
Chronic Disease ; Humans ; Lung Diseases/metabolism
Czasopismo naukowe
Tytuł :
Boosting transfection efficiency: A systematic study using layer-by-layer based gene delivery platform.
Autorzy :
Tarakanchikova YV; Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russian Federation; Nanobiotechnology Laboratory, St. Petersburg Academic University, 194021 St. Petersburg, Russian Federation.
Linnik DS; Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russian Federation.
Mashel T; Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russian Federation; Department of Applied Optics, ITMO University, Kronverkskiy pr. 49, 197101 St. Petersburg, Russian Federation.
Muslimov AR; Nanobiotechnology Laboratory, St. Petersburg Academic University, 194021 St. Petersburg, Russian Federation.
Pavlov S; Ioffe Institute, Politekhnicheskaya Ulitsa, 26, 194021 St. Petersburg, Russian Federation.
Lepik KV; R.M. Gorbacheva Research Institute for Pediatric Oncology, Hematology and Transplantation, Pavlov University, Lev Tolstoy str., 6/8, 197022 St. Petersburg, Russian Federation.
Zyuzin MV; Department of Physics and Engineering, ITMO University, Lomonosova 9, 191002 St. Petersburg, Russian Federation.
Sukhorukov GB; Skolkovo Institute of Science and Technology, 143026 Moscow, Russian Federation; School of Engineering and Material Science, Queen Mary University of London, London, United Kingdom. Electronic address: .
Timin AS; Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St. Petersburg, Russian Federation; National Research Tomsk Polytechnic University, Lenin Avenue, 30, 634050 Tomsk, Russian Federation. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2021 Jul; Vol. 126, pp. 112161. Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article
MeSH Terms :
DNA*
Gene Transfer Techniques*
Genetic Therapy ; Particle Size ; Plasmids/genetics ; Transfection
Czasopismo naukowe
Tytuł :
Strategic targeting of non-small-cell lung cancer utilizing genetic material-based delivery platforms of nanotechnology.
Autorzy :
Chaudhary S; Department of Applied Sciences, Maharaja Surajmal Institute of Technology, GGSIP University, New Delhi, India.
Singh A; Department of Chemistry, University of Delhi, Delhi, India.; Nano-bioconjugate Chemistry Lab, Cluster Innovation Centre, University of Delhi, Delhi, India.
Kumar P; Department of Chemistry, University of Delhi, Delhi, India.; Nano-bioconjugate Chemistry Lab, Cluster Innovation Centre, University of Delhi, Delhi, India.
Kaushik M; Nano-bioconjugate Chemistry Lab, Cluster Innovation Centre, University of Delhi, Delhi, India.
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Źródło :
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Jul; Vol. 35 (7), pp. e22784. Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/therapy
Gene Transfer Techniques*
Genetic Therapy*
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/therapy
Nanoparticles/*therapeutic use
Animals ; Cell Line, Tumor ; Humans ; Nanotechnology
Czasopismo naukowe
Tytuł :
Manipulation of genes could inhibit SARS-CoV-2 infection that causes COVID-19 pandemics.
Autorzy :
Banerjee A; Department of Physiology (UG & PG), Serampore College, Serampore, Hooghly 712201, India.
Mukherjee S; Department of Physiology (UG & PG), Serampore College, Serampore, Hooghly 712201, India.
Maji BK; Department of Physiology (UG & PG), Serampore College, Serampore, Hooghly 712201, India.
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Źródło :
Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2021 Jul; Vol. 246 (14), pp. 1643-1649. Date of Electronic Publication: 2021 Apr 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Transfer Techniques*
Antiviral Agents/*pharmacology
COVID-19/*virology
Host-Pathogen Interactions/*physiology
SARS-CoV-2/*genetics
Antiviral Agents/administration & dosage ; COVID-19/epidemiology ; COVID-19/genetics ; CRISPR-Cas Systems ; Gene Editing/methods ; Host-Pathogen Interactions/genetics ; Humans ; RNA, Guide/administration & dosage ; RNA, Guide/pharmacology ; SARS-CoV-2/pathogenicity
Czasopismo naukowe
Tytuł :
A Comparison of Focused and Unfocused Ultrasound for Microbubble-Mediated Gene Delivery.
Autorzy :
Anderson CD; Department of Medicine, John A. Burns School of Medicine, Honolulu, Hawaii, USA.
Walton CB; University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Shohet RV; Department of Medicine, John A. Burns School of Medicine, Honolulu, Hawaii, USA. Electronic address: .
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Źródło :
Ultrasound in medicine & biology [Ultrasound Med Biol] 2021 Jul; Vol. 47 (7), pp. 1785-1800. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Transfer Techniques*
Microbubbles*
Ultrasonic Waves*
Animals ; Heart ; Liver ; Mice ; Mice, Inbred C57BL ; Plasmids
Czasopismo naukowe
Tytuł :
Lactoferrin-Bearing Gold Nanocages for Gene Delivery in Prostate Cancer Cells in vitro.
Autorzy :
Almowalad J; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK.
Somani S; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK.
Laskar P; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK.
Meewan J; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK.
Tate RJ; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK.
Mullin M; College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.
Dufès C; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Jun 30; Vol. 16, pp. 4391-4407. Date of Electronic Publication: 2021 Jun 30 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
Drug Carriers/*chemistry
Gold/*chemistry
Lactoferrin/*chemistry
Prostatic Neoplasms/*genetics
Prostatic Neoplasms/*pathology
DNA/administration & dosage ; DNA/chemistry ; DNA/genetics ; Genetic Therapy ; Humans ; Male ; Plasmids/genetics ; Polyethylene Glycols/chemistry ; Polyethyleneimine/chemistry ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/therapy ; Transfection
Czasopismo naukowe
Tytuł :
Hyaluronan as a Prominent Biomolecule with Numerous Applications in Medicine.
Autorzy :
Valachová K; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská Cesta 9, 84104 Bratislava, Slovakia.
Šoltés L; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská Cesta 9, 84104 Bratislava, Slovakia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 30; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cosmetics*/chemistry
Cosmetics*/therapeutic use
Gene Transfer Techniques*
Hyaluronic Acid*/chemistry
Hyaluronic Acid*/therapeutic use
Tissue Engineering*
Osteoarthritis/*drug therapy
Wound Healing/*drug effects
Humans
Czasopismo naukowe

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