Temat: "Gene knockdown" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Central 5-HTergic hyperactivity induces myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)-like pathophysiology.
Autorzy:: Lee JS; Research Center for CFS/ME, Daejeon Hospital of Daejeon University, Daejeon, Republic of Korea.; Institute of Bioscience & Integrative Medicine, Daejeon University, Daejeon, Republic of Korea.
Kang JY; Institute of Bioscience & Integrative Medicine, Daejeon University, Daejeon, Republic of Korea.
Park SY; Korean Medical College of Daejeon University, Daejeon, Republic of Korea.
Hwang SJ; Institute of Bioscience & Integrative Medicine, Daejeon University, Daejeon, Republic of Korea.
Bae SJ; College of Medicine, Kosin University, Busan, Republic of Korea.
Son CG; Research Center for CFS/ME, Daejeon Hospital of Daejeon University, Daejeon, Republic of Korea. .; Institute of Bioscience & Integrative Medicine, Daejeon University, Daejeon, Republic of Korea. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2024 Jan 08; Vol. 22 (1), pp. 34. Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:: Journal Article
MeSH Terms:: Fatigue Syndrome, Chronic*
Animals ; Mice ; Serotonin ; Disease Models, Animal ; Gene Knockdown Techniques ; Hypothalamo-Hypophyseal System

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: The choice of negative control antisense oligonucleotides dramatically impacts downstream analysis depending on the cellular background.
Autorzy:: Ducoli L; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Vladimir-Prelog-Weg 3, 8093, Zurich, Switzerland.; Molecular Life Sciences PhD Program, Swiss Federal Institute of Technology and University of Zurich, Zurich, Switzerland.
Agrawal S; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Hon CC; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Ramilowski JA; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Sibler E; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Vladimir-Prelog-Weg 3, 8093, Zurich, Switzerland.; Molecular Life Sciences PhD Program, Swiss Federal Institute of Technology and University of Zurich, Zurich, Switzerland.
Tagami M; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Itoh M; RIKEN Preventive Medicine and Diagnosis Innovation Program, RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Kondo N; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Abugessaisa I; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Hasegawa A; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Kasukawa T; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Suzuki H; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Carninci P; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.; Human Technopole, Via Cristina Belgioioso 171, 20157, Milan, Italy.
Shin JW; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
de Hoon MJL; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.
Detmar M; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Vladimir-Prelog-Weg 3, 8093, Zurich, Switzerland. .; Pokaż więcej
Źródło:: BMC genomic data [BMC Genom Data] 2021 Sep 14; Vol. 22 (1), pp. 33. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Knockdown Techniques/*methods
Oligonucleotides, Antisense/*genetics
Organ Specificity/*genetics
RNA, Long Noncoding/*genetics
Adult ; Endothelial Cells/metabolism ; Gene Knockdown Techniques/standards ; Humans ; Lymphatic System/cytology ; Lymphatic System/metabolism ; Oligonucleotides, Antisense/standards ; Transcriptome

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: LncRNA-PVT1 was identified as a key regulator for TMZ resistance and STAT-related pathway in glioma.
Autorzy:: Chen Y; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China.
Ma F; Department of Intensive Care Unit, The Third People's Hospital of Zhengzhou, Zhengzhou, China.
Zhang Z; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China.
Guo Y; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China.
Shen H; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China.
Chen H; Department of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No.7 WeiWu Street, 450003, Zhengzhou, Zhengzhou, China. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2023 May 18; Vol. 23 (1), pp. 455. Date of Electronic Publication: 2023 May 18.
Typ publikacji:: Journal Article
MeSH Terms:: RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Temozolomide*/pharmacology
Temozolomide*/therapeutic use
Drug Resistance, Neoplasm*/genetics
Gene Expression Regulation, Neoplastic*/genetics
Glioma*/drug therapy
Glioma*/genetics
Glioma*/physiopathology
Gene Knockdown Techniques ; Carcinogenesis/genetics ; Survival Analysis ; STAT Transcription Factors/metabolism ; Janus Kinases/metabolism ; Cell Line, Tumor ; Humans ; Male ; Female ; Adult ; Middle Aged ; Biomarkers, Tumor/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Circ-SPG11 knockdown hampers IL-1β-induced osteoarthritis progression via targeting miR-337-3p/ADAMTS5.
Autorzy:: Liu Y; Department of Orthopedics, Shijiazhuang People's Hospital, No. 365 Jianhua South Road, Shijiazhang, Hebei, 050000, People's Republic of China.
Li Q; Department of Orthopedics, Shijiazhuang People's Hospital, No. 365 Jianhua South Road, Shijiazhang, Hebei, 050000, People's Republic of China.
Gao Z; Department of Orthopedics, Shijiazhuang People's Hospital, No. 365 Jianhua South Road, Shijiazhang, Hebei, 050000, People's Republic of China.
Lei F; Department of Orthopedics, Shijiazhuang People's Hospital, No. 365 Jianhua South Road, Shijiazhang, Hebei, 050000, People's Republic of China. .
Gao X; Department of Orthopedics, Shijiazhuang People's Hospital, No. 365 Jianhua South Road, Shijiazhang, Hebei, 050000, People's Republic of China.; Pokaż więcej
Źródło:: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Jun 17; Vol. 16 (1), pp. 392. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
ADAMTS5 Protein/*genetics
ADAMTS5 Protein/*metabolism
Interleukin-1beta/*adverse effects
MicroRNAs/*genetics
MicroRNAs/*metabolism
Osteoarthritis, Knee/*genetics
Proteins/*genetics
RNA, Circular/*genetics
Cell Line ; Disease Progression ; Down-Regulation/genetics ; Gene Expression Regulation/genetics ; Humans ; Osteoarthritis, Knee/etiology ; Proteins/physiology ; RNA, Circular/physiology ; Up-Regulation/genetics

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Knock-down of LRP/LR influences signalling pathways in late-stage colorectal carcinoma cells.
Autorzy:: Vania L; School of Molecular and Cell Biology, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, Republic of South Africa.
Morris G; School of Molecular and Cell Biology, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, Republic of South Africa.
Ferreira E; School of Molecular and Cell Biology, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, Republic of South Africa.
Weiss SFT; School of Molecular and Cell Biology, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, Republic of South Africa. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2021 Apr 09; Vol. 21 (1), pp. 392. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
Signal Transduction*
Colorectal Neoplasms/*genetics
Colorectal Neoplasms/*metabolism
Receptors, Laminin/*genetics
Receptors, Laminin/*metabolism
Apoptosis/genetics ; Cell Line, Tumor ; Cell Survival/genetics ; Colorectal Neoplasms/pathology ; Gene Expression Profiling ; Humans ; Neoplasm Staging ; Proteome ; Proteomics/methods ; RNA, Small Interfering/genetics ; Telomerase/metabolism ; Transcriptome ; Tumor Cells, Cultured

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Knockdown of Circ_SLC39A8 protects against the progression of osteoarthritis by regulating miR-591/IRAK3 axis.
Autorzy:: Yu J; Department of Orthopaedics, Yichang Central People's Hospital, 183 Yiling Avenue, Wujiagang District, Yichang City, 443003, Hubei Province, P. R. China.
Qin Y; Department of Nuclear Medicine, Yichang Central People's Hospital, 183 Yiling Avenue, Wujiagang District, Yichang City, 443003, Hubei Province, P. R. China.
Zhou N; Department of Orthopaedics, Yichang Central People's Hospital, 183 Yiling Avenue, Wujiagang District, Yichang City, 443003, Hubei Province, P. R. China. .; Pokaż więcej
Źródło:: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Mar 03; Vol. 16 (1), pp. 170. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
Cation Transport Proteins/*genetics
Cation Transport Proteins/*physiology
Chondrocytes/*metabolism
Interleukin-1 Receptor-Associated Kinases/*metabolism
MicroRNAs/*metabolism
Osteoarthritis/*genetics
Aged ; Apoptosis/genetics ; Cell Survival/genetics ; Cells, Cultured ; Chondrocytes/physiology ; Disease Progression ; Down-Regulation/genetics ; Female ; Humans ; Interleukin-1 Receptor-Associated Kinases/genetics ; Male ; MicroRNAs/genetics ; Middle Aged ; Osteoarthritis/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Circular RNA circ_0081001 knockdown enhances methotrexate sensitivity in osteosarcoma cells by regulating miR-494-3p/TGM2 axis.
Autorzy:: Wei W; Department of Orthopedics, Shaoxing Shangyu People's Hospital, No. 517 Civic Avenue, Baiguan Street, Shangyu District, Shaoxing, Zhejiang, 312300, China. .
Ji L; Department of Orthopedics, Shaoxing Shangyu People's Hospital, No. 517 Civic Avenue, Baiguan Street, Shangyu District, Shaoxing, Zhejiang, 312300, China.
Duan W; Department of Orthopedics, Shaoxing Shangyu People's Hospital, No. 517 Civic Avenue, Baiguan Street, Shangyu District, Shaoxing, Zhejiang, 312300, China.
Zhu J; Department of Orthopedics, Shaoxing Shangyu People's Hospital, No. 517 Civic Avenue, Baiguan Street, Shangyu District, Shaoxing, Zhejiang, 312300, China.; Pokaż więcej
Źródło:: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Jan 13; Vol. 16 (1), pp. 50. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
Drug Resistance, Neoplasm/*genetics
GTP-Binding Proteins/*genetics
GTP-Binding Proteins/*metabolism
Gene Expression Regulation, Neoplastic/*genetics
Methotrexate/*pharmacology
MicroRNAs/*genetics
MicroRNAs/*metabolism
Osteosarcoma/*genetics
Osteosarcoma/*pathology
RNA, Circular/*genetics
Transglutaminases/*genetics
Transglutaminases/*metabolism
Cell Line, Tumor ; Humans ; Molecular Targeted Therapy ; Osteosarcoma/drug therapy ; Protein Glutamine gamma Glutamyltransferase 2 ; RNA, Circular/physiology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Yulink, predicted from evolutionary analysis, is involved in cardiac function.
Autorzy:: Kuo MW; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, 333, Taiwan.
Tsai HH; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, 333, Taiwan.
Wang SH; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, 333, Taiwan.
Chen YY; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, 333, Taiwan.
Yu AL; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, 333, Taiwan.; Department of Pediatrics, University of California, San Diego, CA, USA.
Yu J; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, 333, Taiwan. .; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan. .; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2021 Jan 11; Vol. 28 (1), pp. 7. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
Myocytes, Cardiac/*physiology
Animals ; Humans ; Mice ; Zebrafish

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice.
Autorzy:: Miyata S; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi, 371-8511, Japan. s_.
Kakizaki T; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi, 371-8511, Japan.
Fujihara K; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi, 371-8511, Japan.
Obinata H; Laboratory for Analytical Instruments, Education and Research Support Center, Gunma University Graduate School of Medicine, Maebashi, 371-8511, Japan.
Hirano T; Laboratory for Analytical Instruments, Education and Research Support Center, Gunma University Graduate School of Medicine, Maebashi, 371-8511, Japan.
Nakai J; Division of Oral Physiology, Department of Oral Function and Morphology, Tohoku University Graduate School of Dentistry, Sendai, 980-8575, Japan.
Tanaka M; Laboratory for Behavioral Genetics, RIKEN Brain Science Institute, Wako, 351-0198, Japan.
Itohara S; Laboratory for Behavioral Genetics, RIKEN Brain Science Institute, Wako, 351-0198, Japan.
Watanabe M; Department of Anatomy, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan.
Tanaka KF; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Abe M; Department of Animal Model Development, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
Sakimura K; Department of Animal Model Development, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
Yanagawa Y; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi, 371-8511, Japan. .; Pokaż więcej
Źródło:: Molecular brain [Mol Brain] 2021 Jan 07; Vol. 14 (1), pp. 5. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Emotions*
Gene Knockdown Techniques*
Glutamate Decarboxylase/*metabolism
Animals ; Animals, Newborn ; Behavior, Animal/drug effects ; Doxycycline/pharmacology ; Glutamic Acid/metabolism ; Homozygote ; Mice ; gamma-Aminobutyric Acid/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Knockdown of long non-coding RNA LEF1-AS1 attenuates apoptosis and inflammatory injury of microglia cells following spinal cord injury.
Autorzy:: Cui SY; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Zhang W; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Cui ZM; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Yi H; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Xu DW; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Liu W; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China.
Zhu XH; Department of Orthopedic, Nantong First People's Hospital & The Second Affiliated Hospital of Nantong University, No. 6 Haierxiangbei Road, Nantong, 226001, Jiangsu Province, China. .; Pokaż więcej
Źródło:: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Jan 06; Vol. 16 (1), pp. 6. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
Apoptosis/*genetics
Lymphoid Enhancer-Binding Factor 1/*genetics
Lymphoid Enhancer-Binding Factor 1/*physiology
Microglia/*pathology
RNA, Long Noncoding/*genetics
RNA, Long Noncoding/*physiology
Spinal Cord Injuries/*genetics
Spinal Cord Injuries/*pathology
Animals ; Cell Survival/genetics ; Disease Progression ; Down-Regulation ; Inflammation ; Lymphoid Enhancer-Binding Factor 1/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Rats, Sprague-Dawley ; Rats, Wistar ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Up-Regulation ; Rats

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Knockdown of Son, a mouse homologue of the ZTTK syndrome gene, causes neuronal migration defects and dendritic spine abnormalities.
Autorzy:: Ueda M; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, 4800392, Japan.
Matsuki T; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, 4800392, Japan.
Fukada M; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, 4800392, Japan.
Eda S; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, 4800392, Japan.
Toya A; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, 4800392, Japan.; Department of Neurobiochemistry, Nagoya University School of Medicine, Nagoya, Aichi, 4668560, Japan.
Iio A; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, 4800392, Japan.; Biogate Co. Ltd., 331-1 Ohmori, Yamagata, Gifu, 5012123, Japan.
Tabata H; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, 4800392, Japan.
Nakayama A; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, 4800392, Japan. .; Department of Neurobiochemistry, Nagoya University School of Medicine, Nagoya, Aichi, 4668560, Japan. .; Pokaż więcej
Źródło:: Molecular brain [Mol Brain] 2020 May 24; Vol. 13 (1), pp. 80. Date of Electronic Publication: 2020 May 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Movement*
Gene Knockdown Techniques*
Abnormalities, Multiple/*genetics
DNA-Binding Proteins/*genetics
Dendritic Spines/*pathology
Nuclear Proteins/*genetics
Animals ; Brain/metabolism ; DNA-Binding Proteins/metabolism ; HEK293 Cells ; Humans ; Mice ; Mutation/genetics ; Nuclear Proteins/metabolism ; Pyramidal Cells/metabolism ; Syndrome

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Exploring the changing landscape of cell-to-cell variation after CTCF knockdown via single cell RNA-seq.
Autorzy:: Wang W; Department of Biology, Southern University of Science and Technology, Shenzhen, 518055, Guangdong, China.
Ren G; Systems Biology Center, Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Hong N; Department of Biology, Southern University of Science and Technology, Shenzhen, 518055, Guangdong, China. .
Jin W; Department of Biology, Southern University of Science and Technology, Shenzhen, 518055, Guangdong, China. .; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2019 Dec 26; Vol. 20 (1), pp. 1015. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
RNA-Seq*
Single-Cell Analysis*
CCCTC-Binding Factor/*deficiency
CCCTC-Binding Factor/*genetics
Animals ; Cell Line, Tumor ; Mice

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Effect of CFIm68 knockdown on RNA polymerase II transcription.
Autorzy:: Tellier M; Sir William Dunn School of Pathology, University of Oxford, South Park Roads, Oxford, OX1 3RE, UK. .
Hardy JG; Sir William Dunn School of Pathology, University of Oxford, South Park Roads, Oxford, OX1 3RE, UK.
Norbury CJ; Sir William Dunn School of Pathology, University of Oxford, South Park Roads, Oxford, OX1 3RE, UK.
Murphy S; Sir William Dunn School of Pathology, University of Oxford, South Park Roads, Oxford, OX1 3RE, UK.; Pokaż więcej
Źródło:: BMC research notes [BMC Res Notes] 2019 Sep 02; Vol. 12 (1), pp. 554. Date of Electronic Publication: 2019 Sep 02.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
Transcription, Genetic*
RNA Polymerase II/*genetics
mRNA Cleavage and Polyadenylation Factors/*metabolism
HEK293 Cells ; Humans

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells.
Autorzy:: Treeck O; Department of Obstetrics and Gynecology, University Medical Center Regensburg, Landshuter Str. 65, 93053, Regensburg, Germany. .
Diepolder E; Department of Obstetrics and Gynecology, University Medical Center Regensburg, Landshuter Str. 65, 93053, Regensburg, Germany.
Skrzypczak M; Second Department of Gynecology, Medical University of Lublin, Lublin, Poland.
Schüler-Toprak S; Department of Obstetrics and Gynecology, University Medical Center Regensburg, Landshuter Str. 65, 93053, Regensburg, Germany.
Ortmann O; Department of Obstetrics and Gynecology, University Medical Center Regensburg, Landshuter Str. 65, 93053, Regensburg, Germany.; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2019 Jul 29; Vol. 19 (1), pp. 745. Date of Electronic Publication: 2019 Jul 29.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockdown Techniques*
Transcriptome*
Adenocarcinoma/*genetics
Cell Proliferation/*genetics
Endometrial Neoplasms/*genetics
Estrogen Receptor beta/*genetics
Adenocarcinoma/metabolism ; Apoptosis/genetics ; Cell Differentiation/genetics ; Cell Line, Tumor ; Endometrial Neoplasms/metabolism ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; RNA, Small Interfering/metabolism ; Transfection

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus.
Autorzy:: Ranade D; Indian Institute of Science Education and Research (IISER)-Pune, Dr. Homi Bhabha Road, Biology, Room#B-216, 1st Floor, Main Building, Pashan, Pune, Maharashtra, 411008, India.
Pradhan R; Indian Institute of Science Education and Research (IISER)-Pune, Dr. Homi Bhabha Road, Biology, Room#B-216, 1st Floor, Main Building, Pashan, Pune, Maharashtra, 411008, India.
Jayakrishnan M; Indian Institute of Science Education and Research (IISER)-Pune, Dr. Homi Bhabha Road, Biology, Room#B-216, 1st Floor, Main Building, Pashan, Pune, Maharashtra, 411008, India.
Hegde S; Indian Institute of Science Education and Research (IISER)-Pune, Dr. Homi Bhabha Road, Biology, Room#B-216, 1st Floor, Main Building, Pashan, Pune, Maharashtra, 411008, India.
Sengupta K; Indian Institute of Science Education and Research (IISER)-Pune, Dr. Homi Bhabha Road, Biology, Room#B-216, 1st Floor, Main Building, Pashan, Pune, Maharashtra, 411008, India. .; Pokaż więcej
Źródło:: BMC molecular and cell biology [BMC Mol Cell Biol] 2019 May 22; Vol. 20 (1), pp. 11. Date of Electronic Publication: 2019 May 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Knockdown Techniques*
Cell Nucleus/*genetics
Chromatin/*metabolism
Interphase/*genetics
Lamin Type A/*genetics
Membrane Proteins/*genetics
Nuclear Proteins/*genetics
Actins/metabolism ; Cell Line, Tumor ; Chromosome Positioning/genetics ; Chromosomes, Human, Pair 18/genetics ; Chromosomes, Human, Pair 19/genetics ; Cytoskeleton/metabolism ; Gene Expression Regulation, Neoplastic ; Genetic Loci ; Humans ; Kallikreins/genetics ; Muscle Proteins/genetics ; Myosin Type I/metabolism ; Nuclear Envelope/genetics ; Polymerization ; Proto-Oncogene Proteins c-bcl-2/genetics ; RNA, Small Interfering/genetics ; Smad2 Protein/genetics ; Transfection

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma.
Autorzy:: Dai B; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zhang X; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Shang R; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Wang J; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Yang X; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zhang H; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Liu Q; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Wang D; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China. .
Wang L; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China. .
Dou K; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2018 Dec 13; Vol. 16 (1), pp. 99. Date of Electronic Publication: 2018 Dec 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Knockdown Techniques*
Carcinoma, Hepatocellular/*pathology
GTPase-Activating Proteins/*deficiency
GTPase-Activating Proteins/*genetics
Liver Neoplasms/*pathology
rac1 GTP-Binding Protein/*metabolism
Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cell Transformation, Neoplastic ; Disease Progression ; Epithelial-Mesenchymal Transition/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Metastasis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Akt1 inhibition promotes breast cancer metastasis through EGFR-mediated β-catenin nuclear accumulation.
Autorzy:: Li W; Institute for innovative drug design and evaluation, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China.
Hou JZ; Institute for innovative drug design and evaluation, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China.
Niu J; Institute for innovative drug design and evaluation, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China.
Xi ZQ; Institute for innovative drug design and evaluation, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China.
Ma C; Institute for innovative drug design and evaluation, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China.
Sun H; Institute for innovative drug design and evaluation, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China.
Wang CJ; The Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, N. Jinming Ave, Kaifeng, 475004, China.
Fang D; Institute for innovative drug design and evaluation, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China. .
Li Q; Institute for innovative drug design and evaluation, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China. .
Xie SQ; Institute of Chemical Biology, School of Pharmacy, Henan University, N. Jinming Ave, Kaifeng, 475004, China. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2018 Nov 16; Vol. 16 (1), pp. 82. Date of Electronic Publication: 2018 Nov 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Knockdown Techniques*
Breast Neoplasms/*pathology
Cell Nucleus/*metabolism
ErbB Receptors/*metabolism
Proto-Oncogene Proteins c-akt/*deficiency
Proto-Oncogene Proteins c-akt/*genetics
beta Catenin/*metabolism
Active Transport, Cell Nucleus/drug effects ; Active Transport, Cell Nucleus/genetics ; Cell Nucleus/drug effects ; ErbB Receptors/antagonists & inhibitors ; Gefitinib/pharmacology ; Humans ; MAP Kinase Signaling System/drug effects ; MAP Kinase Signaling System/genetics ; MCF-7 Cells ; Neoplasm Metastasis ; Phosphatidylinositol 3-Kinases/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Circ_FURIN knockdown assuages Testosterone-induced human ovarian granulosa-like tumor cell disorders by sponging miR-423-5p to reduce MTM1 expression in polycystic ovary syndrome.
Autorzy:: Xu X; Department of Obstetrical, The Hospital of Bayannaoer, Bayannaoer City, Inner Mongolia, China.
Guan R; Department of Gynaecology, The Hospital of Bayannaoer, Bayannaoer City, Inner Mongolia, China.
Gong K; Department of Obstetrical, The Hospital of Bayannaoer, Bayannaoer City, Inner Mongolia, China.
Xie H; Department of Oncology, Huai'an Second People's Hospital, Affiliated to Xuzhou Medical University, Qingjiangpu District, Huai'an City, No.62, Huaihai South Road, 223001, Jiangsu Province, China. .
Shi L; Department of Obstetrics and Gynecology, Hongze Huai'an District People's Hospital, Hongze District, Huai'an City, No.102 Dongfeng Road, 223001, Jiangsu Province, China. .; Pokaż więcej
Źródło:: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2022 Feb 17; Vol. 20 (1), pp. 32. Date of Electronic Publication: 2022 Feb 17.
Typ publikacji:: Journal Article
MeSH Terms:: Granulosa Cell Tumor/*genetics
MicroRNAs/*genetics
Polycystic Ovary Syndrome/*genetics
Protein Tyrosine Phosphatases, Non-Receptor/*genetics
RNA, Circular/*genetics
Apoptosis/genetics ; Cell Proliferation/genetics ; Cells, Cultured ; Female ; Furin/genetics ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Granulosa Cell Tumor/chemically induced ; Granulosa Cell Tumor/pathology ; Humans ; Models, Biological ; Polycystic Ovary Syndrome/chemically induced ; Polycystic Ovary Syndrome/metabolism ; Polycystic Ovary Syndrome/pathology ; RNA, Circular/physiology ; Testosterone/adverse effects

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: CircCDK17 knockdown inhibits tumor progression and cell glycolysis by downregulaing YWHAZ expression through sponging miR-1294 in cervical cancer.
Autorzy:: Chen R; Department of Gynaecology and Obstetrics, Henan Provincial People's Hospital, Peoples Hospital of Zhengzhou University, School of Clinical Medicine Henan University, No. 7 Weiwu Road Jinshui District, Zhengzhou, 450003, Henan, China.
Liang F; Department of Gynaecology and Obstetrics, Henan Provincial People's Hospital, Peoples Hospital of Zhengzhou University, School of Clinical Medicine Henan University, No. 7 Weiwu Road Jinshui District, Zhengzhou, 450003, Henan, China.
Yan J; Department of Gynaecology and Obstetrics, Henan Provincial People's Hospital, Peoples Hospital of Zhengzhou University, School of Clinical Medicine Henan University, No. 7 Weiwu Road Jinshui District, Zhengzhou, 450003, Henan, China.
Wang Y; Department of Gynaecology and Obstetrics, Henan Provincial People's Hospital, Peoples Hospital of Zhengzhou University, School of Clinical Medicine Henan University, No. 7 Weiwu Road Jinshui District, Zhengzhou, 450003, Henan, China. .; Pokaż więcej
Źródło:: Journal of ovarian research [J Ovarian Res] 2022 Feb 15; Vol. 15 (1), pp. 24. Date of Electronic Publication: 2022 Feb 15.
Typ publikacji:: Journal Article
MeSH Terms:: 14-3-3 Proteins*/genetics
14-3-3 Proteins*/metabolism
MicroRNAs*/genetics
RNA, Circular*/genetics
Uterine Cervical Neoplasms*/genetics
Uterine Cervical Neoplasms*/metabolism
Uterine Cervical Neoplasms*/pathology
Animals ; Female ; Humans ; Mice ; Apoptosis/genetics ; Cell Movement/genetics ; Cell Nucleus/metabolism ; Cell Proliferation/genetics ; Cytoplasm/metabolism ; Down-Regulation ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Gene Silencing ; Glycolysis/genetics ; HeLa Cells ; Neoplasm Transplantation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Up-regulation of MTHFD2 is associated with clinicopathological characteristics and poor survival in ovarian cancer, possibly by regulating MOB1A signaling.
Autorzy:: Cui X; Reproductive Medicine Center, The affiliated Children's Hospital of Shanxi Medical University, Children's Hospital of Shanxi, Women Health Center of Shanxi, Taiyuan, 030001, China.; Gynaecology and Obstetrics Department, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Su H; Gynaecology and Obstetrics Department, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Yang J; Gynaecology and Obstetrics Department, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Wu X; Reproductive Medicine Center, The affiliated Children's Hospital of Shanxi Medical University, Children's Hospital of Shanxi, Women Health Center of Shanxi, Taiyuan, 030001, China.
Huo K; Breast Surgery Department, Tumor Hospital of Shanxi, Affiliated of Shanxi Medical University, Taiyuan, 030000, China.
Jing X; Gynaecology and Obstetrics Department, First Hospital of Shanxi Medical University, Taiyuan, 030001, China. .
Zhang S; Clinical Laboratory, The Affiliated People's Hospital of Shanxi Medical University, Taiyuan, 030001, China. .; Pokaż więcej
Źródło:: Journal of ovarian research [J Ovarian Res] 2022 Feb 08; Vol. 15 (1), pp. 23. Date of Electronic Publication: 2022 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Adaptor Proteins, Signal Transducing/*metabolism
Aminohydrolases/*genetics
Aminohydrolases/*metabolism
Methylenetetrahydrofolate Dehydrogenase (NADP)/*genetics
Methylenetetrahydrofolate Dehydrogenase (NADP)/*metabolism
Multifunctional Enzymes/*genetics
Multifunctional Enzymes/*metabolism
Ovarian Neoplasms/*genetics
Ovarian Neoplasms/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Adult ; Aged ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Computational Biology ; Databases, Genetic ; Female ; Gene Expression ; Gene Knockdown Techniques ; Humans ; Lymphocytes, Tumor-Infiltrating/pathology ; Middle Aged ; Mutation, Missense ; Neoplasm Invasiveness ; Ovarian Neoplasms/pathology ; Prognosis ; Signal Transduction ; Survival Rate ; Up-Regulation ; Young Adult

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Gene knockdown"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Publikacja

Język