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Tytuł :
Cardiometabolic Traits, Sepsis, and Severe COVID-19: A Mendelian Randomization Investigation.
Autorzy :
Ponsford MJ; Immunodeficiency Centre of Wales, University Hospital Wales, Heath Park, Cardiff, United Kingdom (M.J.P.).; Division of Immunology, Infection, and Inflammation, Tenovus Institute, Cardiff University, United Kingdom (M.J.P., S.J.).
Gkatzionis A; Medical Research Council Biostatistics Unit, School of Clinical Medicine, University of Cambridge, United Kingdom (A.G., A.J.G., V.Z., S.B.).
Walker VM; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, United Kingdom (V.M.W., R.E.W., H.R., B.B., N.D.).; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia (V.M.W.).
Grant AJ; Medical Research Council Biostatistics Unit, School of Clinical Medicine, University of Cambridge, United Kingdom (A.G., A.J.G., V.Z., S.B.).
Wootton RE
Moore LSP; National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance (L.S.P.M.), Imperial College London, United Kingdom.; Chelsea and Westminster National Health Service Foundation Trust, London, United Kingdom (L.S.P.M.).; Imperial Biomedical Research Centre, Imperial College London and Imperial College National Health Service Healthcare Trust, United Kingdom (L.S.P.M.).
Fatumo S; Department of Non-Communicable Diseases Epidemiology, London School of Hygiene and Tropical Medicine, United Kingdom (S.F.).
Mason AM; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, United Kingdom (A.M.M., S.B.).; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, United Kingdom (A.M.M.).
Zuber V; Medical Research Council Biostatistics Unit, School of Clinical Medicine, University of Cambridge, United Kingdom (A.G., A.J.G., V.Z., S.B.).; Department of Epidemiology and Biostatistics, School of Public Health (V.Z., D.G.), Imperial College London, United Kingdom.
Willer C; Departments of Internal Medicine, Human Genetics and Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor (C.W.).
Rasheed H; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, United Kingdom (V.M.W., R.E.W., H.R., B.B., N.D.).; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing (H.R., B.B., K.H., N.D., B.O.Å.), Norwegian University of Science and Technology, Trondheim.
Brumpton B; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, United Kingdom (V.M.W., R.E.W., H.R., B.B., N.D.).; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing (H.R., B.B., K.H., N.D., B.O.Å.), Norwegian University of Science and Technology, Trondheim.; Department of Thoracic Medicine (B.B.), St Olavs Hospital, Trondheim University Hospital, Norway.
Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing (H.R., B.B., K.H., N.D., B.O.Å.), Norwegian University of Science and Technology, Trondheim.; Department of Research, Innovation and Education (K.H.), St Olavs Hospital, Trondheim University Hospital, Norway.
Kristian Damås J; Department of Infectious Diseases (J.K.D.), St Olavs Hospital, Trondheim University Hospital, Norway.; Centre of Molecular Inflammation Research, Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim (J.K.D.).
Davies N; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, United Kingdom (V.M.W., R.E.W., H.R., B.B., N.D.).; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing (H.R., B.B., K.H., N.D., B.O.Å.), Norwegian University of Science and Technology, Trondheim.
Olav Åsvold B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing (H.R., B.B., K.H., N.D., B.O.Å.), Norwegian University of Science and Technology, Trondheim.; Department of Endocrinology (B.O.Å.), St Olavs Hospital, Trondheim University Hospital, Norway.
Solligård E; Gemini Center for Sepsis Research, Department of Circulation and Medical Imaging (E.S., T.R., E.S.), Norwegian University of Science and Technology, Trondheim.; Clinic of Anesthesia and Intensive Care (E.S.), St Olavs Hospital, Trondheim University Hospital, Norway.
Jones S; Division of Immunology, Infection, and Inflammation, Tenovus Institute, Cardiff University, United Kingdom (M.J.P., S.J.).
Burgess S; Medical Research Council Biostatistics Unit, School of Clinical Medicine, University of Cambridge, United Kingdom (A.G., A.J.G., V.Z., S.B.).; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, United Kingdom (A.M.M., S.B.).
Rogne T; Gemini Center for Sepsis Research, Department of Circulation and Medical Imaging (E.S., T.R., E.S.), Norwegian University of Science and Technology, Trondheim.
Gill D; Department of Epidemiology and Biostatistics, School of Public Health (V.Z., D.G.), Imperial College London, United Kingdom.; Novo Nordisk Research Centre Oxford, Old Road Campus, United Kingdom (D.G.).; Clinical Pharmacology and Therapeutics Section, Institute of Medical and Biomedical Education and Institute for Infection and Immunity, St George's, University of London, United Kingdom (D.G.).; Clinical Pharmacology Group, Pharmacy and Medicines Directorate, St George's University Hospitals National Health Service Foundation Trust, London, United Kingdom (D.G.).
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Źródło :
Circulation [Circulation] 2020 Nov 03; Vol. 142 (18), pp. 1791-1793. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene-Environment Interaction*
Polymorphism, Single Nucleotide*
Betacoronavirus/*pathogenicity
Coronavirus Infections/*genetics
Obesity/*genetics
Pneumonia, Viral/*genetics
Sepsis/*genetics
Smoking/*genetics
Body Mass Index ; Case-Control Studies ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/genetics ; Dyslipidemias/epidemiology ; Dyslipidemias/genetics ; Genetic Association Studies ; Genetic Predisposition to Disease ; Host-Pathogen Interactions ; Humans ; Mendelian Randomization Analysis ; Obesity/epidemiology ; Pandemics ; Phenotype ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Risk Factors ; Sepsis/epidemiology ; Sepsis/virology ; Severity of Illness Index ; Smoking/adverse effects ; Smoking/epidemiology
SCR Disease Name :
COVID-19
Raport
Tytuł :
Genotype by environment interaction for gene expression in Drosophila melanogaster.
Autorzy :
Huang W; Program in Genetics, Department of Biological Sciences, W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC, 27695-7614, USA. .; Department of Animal Science, Michigan State University, East Lansing, MI, 48824, USA. .
Carbone MA; Program in Genetics, Department of Biological Sciences, W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC, 27695-7614, USA.; Center for Integrated Fungal Research and Department of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, 27695-7244, USA.
Lyman RF; Program in Genetics, Department of Biological Sciences, W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC, 27695-7614, USA.; Clemson Center for Human Genetics, Clemson University, Greenwood, SC, 29646, USA.
Anholt RRH; Program in Genetics, Department of Biological Sciences, W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC, 27695-7614, USA.; Clemson Center for Human Genetics, Clemson University, Greenwood, SC, 29646, USA.
Mackay TFC; Program in Genetics, Department of Biological Sciences, W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC, 27695-7614, USA. .; Clemson Center for Human Genetics, Clemson University, Greenwood, SC, 29646, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 28; Vol. 11 (1), pp. 5451. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene-Environment Interaction*
Drosophila melanogaster/*genetics
Animals ; Female ; Gene Expression ; Gene Expression Regulation ; Gene Regulatory Networks ; Genes, Insect ; Genetic Variation ; Genotype ; Male ; Quantitative Trait Loci ; RNA-Seq ; Temperature ; Transcriptome
Czasopismo naukowe
Tytuł :
Genotype by environment interaction due to heat stress during gestation and postpartum for milk production of Holstein cattle.
Autorzy :
Menéndez-Buxadera A; Grupo de Melhoramento Animal de Mato Grosso (GMAT), Instituto de Ciências Agrárias e Tecnológicas, Campus Universitário de Rondonópolis, Universidade Federal de Rondonópolis, Avenida dos Estudantes, nº 5055, Rondonópolis, MTCEP 78735-901, Brazil.; Departamento de Genética, Grupo Meragen, Rabanales, Universidad de Córdoba, Cordoba14071, Spain.
Pereira RJ; Grupo de Melhoramento Animal de Mato Grosso (GMAT), Instituto de Ciências Agrárias e Tecnológicas, Campus Universitário de Rondonópolis, Universidade Federal de Rondonópolis, Avenida dos Estudantes, nº 5055, Rondonópolis, MTCEP 78735-901, Brazil.
El Faro L; Centro de Pesquisas de Bovinos de Corte, Instituto de Zootecnia, Rodovia Carlos Tonanni, Km 94, Sertãozinho, SPCEP 14160-900, Brazil.
Santana ML; Grupo de Melhoramento Animal de Mato Grosso (GMAT), Instituto de Ciências Agrárias e Tecnológicas, Campus Universitário de Rondonópolis, Universidade Federal de Rondonópolis, Avenida dos Estudantes, nº 5055, Rondonópolis, MTCEP 78735-901, Brazil.
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Źródło :
Animal : an international journal of animal bioscience [Animal] 2020 Oct; Vol. 14 (10), pp. 2014-2022. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Cattle*/genetics
Cattle Diseases*
Gene-Environment Interaction*
Heat Stress Disorders*/veterinary
Animals ; Brazil ; Female ; Heat-Shock Response ; Hot Temperature ; Humidity ; Lactation ; Milk
Czasopismo naukowe
Tytuł :
Genes and environments, development and time.
Autorzy :
Boyce WT; Department of Pediatrics, University of California, San Francisco, CA 94143.; Department of Psychiatry, University of California, San Francisco, CA 94143.; Program in Child and Brain Development, Canadian Institute for Advanced Research, Toronto, ON M5G 1M1, Canada.
Sokolowski MB; Program in Child and Brain Development, Canadian Institute for Advanced Research, Toronto, ON M5G 1M1, Canada; .; Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON M5S 3B2, Canada.
Robinson GE; Program in Child and Brain Development, Canadian Institute for Advanced Research, Toronto, ON M5G 1M1, Canada.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Neuroscience Program, Department of Entomology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 22; Vol. 117 (38), pp. 23235-23241.
Typ publikacji :
Introductory Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene-Environment Interaction*
Animals ; Biological Evolution ; Epigenesis, Genetic ; Gene Expression Regulation ; Humans ; Time
Czasopismo naukowe
Tytuł :
Regional-scale investigation for microbial competition-through-environment interactions modulating antibiotic resistance.
Autorzy :
Wang Q; State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Jiangsu 210008, China.
Hamilton PB; Canadian Museum of Nature, P. O. Box 3443, Station D, Ottawa, Ontario K1P 6P4, Canada.
Kang F; College of Resources and Environmental Sciences, Nanjing Agricultural University, Jiangsu 210095, China. Electronic address: .
Zhu X; College of Resources and Environmental Sciences, Nanjing Agricultural University, Jiangsu 210095, China.
Zhang Y; College of Public Administration, Nanjing Agricultural University, Jiangsu 210095, China.
Zhao H; State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Jiangsu 210008, China.
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Źródło :
The Science of the total environment [Sci Total Environ] 2020 Sep 10; Vol. 734, pp. 139341. Date of Electronic Publication: 2020 May 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gene-Environment Interaction*
Geologic Sediments*
Anti-Bacterial Agents ; China ; Drug Resistance, Microbial ; Genes, Bacterial
Czasopismo naukowe
Tytuł :
Tumour predisposition and cancer syndromes as models to study gene-environment interactions.
Autorzy :
Carbone M; Thoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI, USA. .
Arron ST; STA, JEC, Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Beutler B; Center for Genetic Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Bononi A; Thoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI, USA.
Cavenee W; Ludwig Institute, University of California, San Diego, San Diego, CA, USA.
Cleaver JE; STA, JEC, Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Croce CM; Department of Cancer Biology and Genetics, Ohio State University, Columbus, OH, USA.
D'Andrea A; Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Foulkes WD; Department of Human Genetics, McGill University, Montreal, QC, Canada.
Gaudino G; Thoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI, USA.
Groden JL; VC Research, University of Illinois, Chicago, IL, USA.
Henske EP; Center for LAM Research, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Hickson ID; Center for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Hwang PM; Cardiovascular Branch, National Institutes of Health, Bethesda, MD, USA.
Kolodner RD; Ludwig Institute, University of California, San Diego, San Diego, CA, USA.
Mak TW; Princess Margaret Cancer Center, University of Toronto, Toronto, ON, Canada.
Malkin D; Division of Haematology/Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Monnat RJ Jr; Department Pathology, Washington University, Seattle, WA, USA.; Department of Genome Science, Washington University, Seattle, WA, USA.
Novelli F; Thoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI, USA.
Pass HI; Department of Cardiovascular Surgery, New York University, New York, NY, USA.
Petrini JH; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Schmidt LS; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Yang H; Thoracic Oncology, University of Hawaii Cancer Center, Honolulu, HI, USA.
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Źródło :
Nature reviews. Cancer [Nat Rev Cancer] 2020 Sep; Vol. 20 (9), pp. 533-549. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Gene-Environment Interaction*
Genetic Predisposition to Disease*
Neoplasms/*genetics
Animals ; Germ-Line Mutation ; Humans
Czasopismo naukowe
Tytuł :
Hypothesis: amyotrophic lateral sclerosis and environmental pollutants.
Autorzy :
Swash M; Barts and The London School of Medicine, Queen Mary University of London and Royal London Hospital, London, UK.; Institute of Neuroscience, University of Lisbon, Lisbon, Portugal.
Eisen A; Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada.
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Źródło :
Muscle & nerve [Muscle Nerve] 2020 Aug; Vol. 62 (2), pp. 187-191. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Historical Article; Journal Article
MeSH Terms :
Environmental Pollutants*
Gene-Environment Interaction*
Life Expectancy*
Amyotrophic Lateral Sclerosis/*epidemiology
Environmental Exposure/*statistics & numerical data
Industrial Development/*statistics & numerical data
Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/history ; C9orf72 Protein/genetics ; Causality ; DNA-Binding Proteins/genetics ; Environmental Exposure/history ; History, 19th Century ; History, 20th Century ; History, 21st Century ; Humans ; Incidence ; Industrial Development/history ; Mutation ; Superoxide Dismutase-1/genetics
Czasopismo naukowe
Tytuł :
Genomic resources for dissecting the role of non-protein coding variation in gene-environment interactions.
Autorzy :
Levings D; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, 1035 University Drive, Duluth, MN, 55812, USA.
Shaw KE; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, 1035 University Drive, Duluth, MN, 55812, USA.
Lacher SE; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, 1035 University Drive, Duluth, MN, 55812, USA. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2020 Aug; Vol. 441, pp. 152505. Date of Electronic Publication: 2020 May 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Gene-Environment Interaction*
Genetic Variation*/genetics
Untranslated Regions*/drug effects
Genomics/*methods
Animals ; Gene Expression ; Genome-Wide Association Study ; Humans ; Polymorphism, Single Nucleotide/genetics
Czasopismo naukowe
Tytuł :
No association between alcohol consumption and risk of atrial fibrillation: A two-sample Mendelian randomization study.
Autorzy :
Jiang Q; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Wang K; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Shi J; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Li M; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Chen M; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address: .
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2020 Jul 24; Vol. 30 (8), pp. 1389-1396. Date of Electronic Publication: 2020 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene-Environment Interaction*
Polymorphism, Single Nucleotide*
Alcohol Drinking/*adverse effects
Atrial Fibrillation/*genetics
Alcohol Drinking/epidemiology ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Mendelian Randomization Analysis ; Phenotype ; Risk Assessment ; Risk Factors
Czasopismo naukowe
Tytuł :
Using a sibling-adoption design to parse genetic and environmental influences on children's body mass index (BMI).
Autorzy :
Tavalire HF; Prevention Science Institute, University of Oregon, Eugene, Oregon, United States of America.; Instutite of Ecology and Evolution, University of Oregon, Eugene, Oregon, United States of America.
Budd EL; Prevention Science Institute, University of Oregon, Eugene, Oregon, United States of America.; Counseling Psychology and Human Services Department, College of Education, University of Oregon, Eugene, Oregon, United States of America.
Natsuaki MN; Department of Psychology, University of California, Riverside, California, United States of America.
Neiderhiser JM; Department of Psychology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Reiss D; Child Study Center, Yale University, New Haven, Connecticut, United States of America.
Shaw DS; Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Ganiban JM; Department of Psychology, George Washington University, Washington, DC, United States of America.
Leve LD; Prevention Science Institute, University of Oregon, Eugene, Oregon, United States of America.; Counseling Psychology and Human Services Department, College of Education, University of Oregon, Eugene, Oregon, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Jul 20; Vol. 15 (7), pp. e0236261. Date of Electronic Publication: 2020 Jul 20 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Adoption*
Body Mass Index*
Gene-Environment Interaction*
Siblings*
Pediatric Obesity/*epidemiology
Adolescent ; Child ; Child Development/physiology ; Child Rearing ; Child, Preschool ; Female ; Humans ; Male ; Pediatric Obesity/genetics ; Pediatric Obesity/physiopathology ; Pediatric Obesity/prevention & control ; Prospective Studies
Czasopismo naukowe
Tytuł :
Deriving stratified effects from joint models investigating gene-environment interactions.
Autorzy :
Laville V; Department of Computational Biology, USR 3756 CNRS, Institut Pasteur, Paris, France. .
Majarian T; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Feitosa MF; Division of Biostatistics, Department of Genetics, Washington University School of Medecine, St. Louis, MO, 63110, USA.
Sung YJ; Division of Biostatistics, Department of Genetics, Washington University School of Medecine, St. Louis, MO, 63110, USA.
Rao DC; Division of Biostatistics, Department of Genetics, Washington University School of Medecine, St. Louis, MO, 63110, USA.
Manning A; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, 02114, USA.
Aschard H; Department of Computational Biology, USR 3756 CNRS, Institut Pasteur, Paris, France. .; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA. .
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Corporate Authors :
CHARGE Gene-Lifestyle Interactions Working Group
Źródło :
BMC bioinformatics [BMC Bioinformatics] 2020 Jun 18; Vol. 21 (1), pp. 251. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Gene-Environment Interaction*
Joints/*physiology
Humans ; Models, Genetic
Czasopismo naukowe
Tytuł :
Validation of genome-wide association study-identified single nucleotide polymorphisms in a case-control study of pancreatic cancer from Taiwan.
Autorzy :
Shan YS; Department of Surgery, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Chen LT; National Institute of Cancer Research, National Health Research Institutes, 1F No 367, Sheng-Li Road, Tainan, 70456, Taiwan.; Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.; Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Ziyou 1st Road, Sanmin District, Kaohsiung, 80756, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Wu JS; Department of Family Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Chang YF; Department of Family Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Lee CT; Department of Family Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Wu CH; Department of Family Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Chiang NJ; National Institute of Cancer Research, National Health Research Institutes, 1F No 367, Sheng-Li Road, Tainan, 70456, Taiwan.; Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Huang HE; Department of Family Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Yen CJ; Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Chao YJ; Department of Surgery, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Tsai HJ; National Institute of Cancer Research, National Health Research Institutes, 1F No 367, Sheng-Li Road, Tainan, 70456, Taiwan.; Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Chen CY; Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Kang JW; Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Kuo CF; Preventive Medicine Center, Taichung Tzu Chi Hospital, 88 Section 1, Fengxing Road, Tanzi District, Taichung, 427, Taiwan.
Tsai CR; National Institute of Cancer Research, National Health Research Institutes, 1F No 367, Sheng-Li Road, Tainan, 70456, Taiwan.
Weng YL; National Institute of Cancer Research, National Health Research Institutes, 1F No 367, Sheng-Li Road, Tainan, 70456, Taiwan.
Yang HC; National Institute of Cancer Research, National Health Research Institutes, 1F No 367, Sheng-Li Road, Tainan, 70456, Taiwan.
Liu HC; Department of Nursing, National Cheng Kung University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, 70456, Taiwan.
Chang JS; National Institute of Cancer Research, National Health Research Institutes, 1F No 367, Sheng-Li Road, Tainan, 70456, Taiwan. .
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Źródło :
Journal of biomedical science [J Biomed Sci] 2020 May 26; Vol. 27 (1), pp. 69. Date of Electronic Publication: 2020 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
Gene-Environment Interaction*
Genome-Wide Association Study*
Polymorphism, Single Nucleotide*
Pancreatic Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Female ; Humans ; Male ; Middle Aged ; Risk Factors ; Taiwan ; Young Adult
Czasopismo naukowe
Tytuł :
A rank-based normalization method with the fully adjusted full-stage procedure in genetic association studies.
Autorzy :
Chien LC; Center for Fundamental Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
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Źródło :
PloS one [PLoS One] 2020 Jun 19; Vol. 15 (6), pp. e0233847. Date of Electronic Publication: 2020 Jun 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene-Environment Interaction*
Models, Genetic*
Genome-Wide Association Study/*methods
Humans ; Normal Distribution ; Polymorphism, Genetic
Czasopismo naukowe
Tytuł :
Effects of low-density urbanization on genetic structure in the Song Sparrow.
Autorzy :
Brewer VN; Department of Biology, New Mexico State University, Las Cruces, NM, United States of America.
Lane SJ; Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States of America.
Sewall KB; Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States of America.
Mabry KE; Department of Biology, New Mexico State University, Las Cruces, NM, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Jun 12; Vol. 15 (6), pp. e0234008. Date of Electronic Publication: 2020 Jun 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene-Environment Interaction*
Genetic Variation*
Sparrows/*genetics
Animals ; Gene Flow ; Gene Frequency ; Microsatellite Repeats ; Urbanization
Czasopismo naukowe
Tytuł :
Genetic and environmental factors associated with homocysteine concentrations in a population of healthy young adults. Analysis of the MAGNETIC study.
Autorzy :
Osadnik T; Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland; 2nd Department of Cardiology and Angiology, Silesian Centre for Heart Diseases, Zabrze, Poland. Electronic address: .
Pawlas N; Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland; Institute of Occupational Medicine and Environmental Health, Sosnowiec, Poland.
Lejawa M; Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland; Kardio-Med Silesia, Zabrze, Poland.
Lisik M; Genetic Outpatient Maria Skłodowska-Curie Memorial Cancer Center, Institute of Oncology Gliwice Branch, Poland.
Osadnik K; Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
Fronczek M; Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland; Kardio-Med Silesia, Zabrze, Poland.
Bujak K; 3rd Department of Cardiology, Silesian Center for Heart Diseases, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
Gąsior M; 3rd Department of Cardiology, Silesian Center for Heart Diseases, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2020 Jun 09; Vol. 30 (6), pp. 939-947. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diet, Healthy*
Feeding Behavior*
Gene-Environment Interaction*
Polymorphism, Genetic*
Homocysteine/*blood
Methylenetetrahydrofolate Reductase (NADPH2)/*genetics
Adolescent ; Adult ; Age Factors ; Biomarkers/blood ; Creatinine/blood ; Female ; Folic Acid/blood ; Healthy Volunteers ; Humans ; Male ; Young Adult
Czasopismo naukowe
Tytuł :
Effects of the Environment and Its Interplay with Genetics in Lung Function throughout Life.
Autorzy :
Fuertes E; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
van der Plaat DA; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Portas L; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Minelli C; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2020 Jun 01; Vol. 201 (11), pp. 1425-1427.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Exposome*
Gene-Environment Interaction*
Child ; Cohort Studies ; Environment ; Europe ; Humans
Czasopismo naukowe
Tytuł :
Incomplete penetrance in primary immunodeficiency: a skeleton in the closet.
Autorzy :
Gruber C; Department of Microbiology, Icahn School of Medicine at Mt. Sinai, New York, NY, 10029, USA.
Bogunovic D; Department of Microbiology, Icahn School of Medicine at Mt. Sinai, New York, NY, 10029, USA. .; Department of Pediatrics, Icahn School of Medicine at Mt. Sinai, New York, NY, 10029, USA. .; Precision Immunology Institute, Icahn School of Medicine at Mt. Sinai, New York, NY, 10029, USA. .; Mindich Child Health and Development Institute, Icahn School of Medicine at Mt. Sinai, New York, NY, 10029, USA. .
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Źródło :
Human genetics [Hum Genet] 2020 Jun; Vol. 139 (6-7), pp. 745-757. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Epigenesis, Genetic*
Gene-Environment Interaction*
Genetic Predisposition to Disease*
Genetic Variation*
Penetrance*
Primary Immunodeficiency Diseases/*genetics
Primary Immunodeficiency Diseases/*pathology
Humans ; Mosaicism ; Primary Immunodeficiency Diseases/immunology
Czasopismo naukowe
Tytuł :
Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago.
Autorzy :
Natri HM; Center for Evolution and Medicine, School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America.; The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
Bobowik KS; Melbourne Integrative Genomics, University of Melbourne, Parkville, Australia.; School of BioSciences, University of Melbourne, Parkville, Australia.; Centre for Stem Cell Systems, University of Melbourne, Parkville, Australia.
Kusuma P; Genome Diversity and Diseases Laboratory, Eijkman Institute for Molecular Biology, Jakarta, Indonesia.; Complexity Institute, Nanyang Technological University, Singapore, Singapore.
Crenna Darusallam C; Genome Diversity and Diseases Laboratory, Eijkman Institute for Molecular Biology, Jakarta, Indonesia.
Jacobs GS; Complexity Institute, Nanyang Technological University, Singapore, Singapore.
Hudjashov G; Statistics and Bioinformatics Group, School of Fundamental Sciences, Massey University, Palmerston North, New Zealand.
Lansing JS; Santa Fe Institute, Santa Fe, New Mexico, United States of America.; Vienna Complexity Science Hub, Vienna, Austria.; Stockholm Resilience Center, Kräftriket, Stockholm, Sweden.
Sudoyo H; Genome Diversity and Diseases Laboratory, Eijkman Institute for Molecular Biology, Jakarta, Indonesia.; Department of Medical Biology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.; Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Banovich NE; The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
Cox MP; Statistics and Bioinformatics Group, School of Fundamental Sciences, Massey University, Palmerston North, New Zealand.
Gallego Romero I; Melbourne Integrative Genomics, University of Melbourne, Parkville, Australia.; School of BioSciences, University of Melbourne, Parkville, Australia.; Centre for Stem Cell Systems, University of Melbourne, Parkville, Australia.
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Źródło :
PLoS genetics [PLoS Genet] 2020 May 26; Vol. 16 (5), pp. e1008749. Date of Electronic Publication: 2020 May 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Methylation*
Gene-Environment Interaction*
Transcriptome*
Ethnic Groups/*genetics
CpG Islands ; Environment ; Epigenesis, Genetic/physiology ; Ethnic Groups/statistics & numerical data ; Gene Expression Profiling/statistics & numerical data ; Genetics, Population ; Genome-Wide Association Study/statistics & numerical data ; Genomics/methods ; Humans ; Indonesia/epidemiology ; Islands/epidemiology ; Pacific Islands/epidemiology ; Pedigree ; Phenotype ; Polymorphism, Single Nucleotide ; RNA-Seq
Czasopismo naukowe
Tytuł :
Improving yield and fruit quality traits in sweet passion fruit: Evidence for genotype by environment interaction and selection of promising genotypes.
Autorzy :
Chavarría-Perez LM; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Giordani W; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Dias KOG; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Costa ZP; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Ribeiro CAM; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Benedetti AR; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Cauz-Santos LA; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Pereira GS; Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America.
Rosa JRBF; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Garcia AAF; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
Vieira MLC; Departamento de Genética, Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Piracicaba, Brasil.
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Źródło :
PloS one [PLoS One] 2020 May 14; Vol. 15 (5), pp. e0232818. Date of Electronic Publication: 2020 May 14 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene-Environment Interaction*
Fruit/*genetics
Passiflora/*genetics
Breeding ; Capsicum/genetics ; Capsicum/growth & development ; Fruit/growth & development ; Genetic Variation/genetics ; Genotype ; Passiflora/growth & development ; Selection, Genetic/genetics
Czasopismo naukowe
Tytuł :
Are genes destiny? Exploring the role of intrauterine environment in moderating genetic influences on body mass.
Autorzy :
Kim J; Department of Sociology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
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Źródło :
American journal of human biology : the official journal of the Human Biology Council [Am J Hum Biol] 2020 May; Vol. 32 (3), pp. e23354. Date of Electronic Publication: 2019 Nov 08.
Typ publikacji :
Journal Article
MeSH Terms :
Gene-Environment Interaction*
Alpha-Ketoglutarate-Dependent Dioxygenase FTO/*genetics
Body Weight/*genetics
Uterus/*physiology
Alpha-Ketoglutarate-Dependent Dioxygenase FTO/metabolism ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Wisconsin
Czasopismo naukowe

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