Temat: "Genes, Immunoglobulin Heavy Chain" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Clinical, histopathological, and molecular features of mucosa-associated lymphoid tissue (MALT) lymphoma carrying the t(X;14) (p11;q32)/GPR34-immunoglobulin heavy chain gene.
Autorzy:: Akasaka T; a Department of Hematology , Tenri Hospital , Tenri , Japan.
Lee YF; b School of Pharmacy , University of Bradford , Bradford , UK.
Novak AJ; c Division of Hematology , Mayo Clinic , Rochester , MN , USA.
Honjo G; d Diagnostic Pathology , Tenri Hospital , Tenri , Japan.
Takeoka K; e Laboratory of Cytogenetics, Tenri Institute of Medical Research , Tenri , Japan.
Maekawa F; e Laboratory of Cytogenetics, Tenri Institute of Medical Research , Tenri , Japan.
Fukutsuka K; e Laboratory of Cytogenetics, Tenri Institute of Medical Research , Tenri , Japan.
Hayashida M; e Laboratory of Cytogenetics, Tenri Institute of Medical Research , Tenri , Japan.
Ohno H; a Department of Hematology , Tenri Hospital , Tenri , Japan.; e Laboratory of Cytogenetics, Tenri Institute of Medical Research , Tenri , Japan.; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2017 Sep; Vol. 58 (9), pp. 1-4. Date of Electronic Publication: 2017 Feb 28.
Typ publikacji:: Case Reports; Letter; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromosomes, Human, Pair 14*
Chromosomes, Human, X*
Genes, Immunoglobulin Heavy Chain*
Translocation, Genetic*
Lymphoma, B-Cell, Marginal Zone/*diagnosis
Lymphoma, B-Cell, Marginal Zone/*genetics
Receptors, Lysophospholipid/*genetics
Aged ; Antibodies, Monoclonal, Murine-Derived/adverse effects ; Antibodies, Monoclonal, Murine-Derived/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cyclophosphamide/adverse effects ; Cyclophosphamide/therapeutic use ; Doxorubicin/adverse effects ; Doxorubicin/therapeutic use ; Exons ; Female ; Genetic Testing ; Humans ; Lymphoma, B-Cell, Marginal Zone/therapy ; Male ; Neoplasm Grading ; Neoplasm Staging ; Prednisone/adverse effects ; Prednisone/therapeutic use ; Rituximab ; Sequence Analysis, DNA ; Treatment Outcome ; Vincristine/adverse effects ; Vincristine/therapeutic use

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Skocz do pozycji: 2.

Tytuł:: Polyreactive antibodies in CLL correlate with the level of immunoglobulins not the number of B lymphocytes.
Autorzy:: Gunti S; a Experimental Medicine Section, Laboratory of Sensory Biology , National Institute of Dental and Craniofacial Research, National Institutes of Health , Bethesda , MD , USA.
Herman SEM; b Hematology Branch, National Institute of Heart, Lung and Blood Institute, National Institutes of Health , Bethesda , MD , USA.
Gottumukkala RVSRK; a Experimental Medicine Section, Laboratory of Sensory Biology , National Institute of Dental and Craniofacial Research, National Institutes of Health , Bethesda , MD , USA.
Xiong Y; a Experimental Medicine Section, Laboratory of Sensory Biology , National Institute of Dental and Craniofacial Research, National Institutes of Health , Bethesda , MD , USA.
Sun C; b Hematology Branch, National Institute of Heart, Lung and Blood Institute, National Institutes of Health , Bethesda , MD , USA.
Carmona GN; a Experimental Medicine Section, Laboratory of Sensory Biology , National Institute of Dental and Craniofacial Research, National Institutes of Health , Bethesda , MD , USA.
Wiestner A; b Hematology Branch, National Institute of Heart, Lung and Blood Institute, National Institutes of Health , Bethesda , MD , USA.
Notkins AL; a Experimental Medicine Section, Laboratory of Sensory Biology , National Institute of Dental and Craniofacial Research, National Institutes of Health , Bethesda , MD , USA.; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2019 Jan; Vol. 60 (1), pp. 242-245. Date of Electronic Publication: 2018 May 09.
Typ publikacji:: Letter; Research Support, N.I.H., Intramural
MeSH Terms:: B-Lymphocytes*
Immunoglobulin M/*blood
Leukemia, Lymphocytic, Chronic, B-Cell/*immunology
Aged ; Case-Control Studies ; Cross Reactions ; Female ; Genes, Immunoglobulin Heavy Chain/genetics ; Healthy Volunteers ; Humans ; Immunoglobulin M/genetics ; Immunoglobulin M/immunology ; Leukemia, Lymphocytic, Chronic, B-Cell/blood ; Leukemia, Lymphocytic, Chronic, B-Cell/genetics ; Lymphocyte Count ; Male ; Observational Studies as Topic

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Skocz do pozycji: 3.

Tytuł:: Immunoglobulin heavy chain V-D-J gene rearrangement and mutational status in Uruguayan patients with chronic lymphocytic leukemia.
Autorzy:: Bianchi S; Institut Pasteur de Montevideo, Montevideo, Uruguay.
Moreno P
Landoni AI
Naya H
Oppezzo P
Dighiero G
Gabús R
Pritsch O; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2010 Nov; Vol. 51 (11), pp. 2070-8. Date of Electronic Publication: 2010 Oct 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Rearrangement, B-Lymphocyte, Heavy Chain*
Genes, Immunoglobulin Heavy Chain*
Mutation*
Immunoglobulin Variable Region/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Adult ; Aged ; DNA Mutational Analysis ; Female ; Gene Frequency ; Geography ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/immunology ; Male ; Middle Aged ; Phylogeny ; Uruguay

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Skocz do pozycji: 4.

Tytuł:: Trametinib for the treatment of IGHV4-34, MAP2K1-mutant variant hairy cell leukemia.
Autorzy:: Andritsos LA; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Grieselhuber NR; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Anghelina M; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Rogers KA; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Roychowdhury S; b Division of Medical Oncology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Reeser JW; b Division of Medical Oncology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Timmers CD; b Division of Medical Oncology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Freud AG; c Department of Pathology , The Ohio State University , Columbus , OH , USA.
Blachly JS; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Lucas DM; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Lozanski G; c Department of Pathology , The Ohio State University , Columbus , OH , USA.
Jones JA; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Williams K; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Oakes C; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.
Jones D; c Department of Pathology , The Ohio State University , Columbus , OH , USA.
Grever MR; a Division of Hematology, Department of Internal Medicine , The Ohio State University , Columbus , OH , USA.; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2018 Apr; Vol. 59 (4), pp. 1008-1011. Date of Electronic Publication: 2017 Sep 18.
Typ publikacji:: Case Reports; Letter
MeSH Terms:: Genes, Immunoglobulin Heavy Chain/*genetics
Leukemia, Hairy Cell/*drug therapy
MAP Kinase Kinase 1/*genetics
Protein Kinase Inhibitors/*therapeutic use
Pyridones/*therapeutic use
Pyrimidinones/*therapeutic use
Humans ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Variable Region/genetics ; Leukemia, Hairy Cell/genetics ; Male ; Middle Aged ; Mutation ; Treatment Outcome

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Skocz do pozycji: 5.

Tytuł:: Immunoglobulin heavy chain variable region gene repertoire and B-cell receptor stereotypes in Indian patients with chronic lymphocytic leukemia.
Autorzy:: Rani L; a Laboratory Oncology Unit , Dr. Bhim Rao Ambedkar Institute Rotary Cancer Hospital (Dr. B.R.A.IRCH), All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India ;
Mathur N; a Laboratory Oncology Unit , Dr. Bhim Rao Ambedkar Institute Rotary Cancer Hospital (Dr. B.R.A.IRCH), All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India ;
Gogia A; b Department of Medical Oncology , Dr. Bhim Rao Ambedkar Institute Rotary Cancer Hospital (Dr. B.R.A.IRCH), All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India ;
Vishnubhatla S; c Department of Biostatistics , All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India ;
Kumar L; b Department of Medical Oncology , Dr. Bhim Rao Ambedkar Institute Rotary Cancer Hospital (Dr. B.R.A.IRCH), All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India ;
Sharma A; b Department of Medical Oncology , Dr. Bhim Rao Ambedkar Institute Rotary Cancer Hospital (Dr. B.R.A.IRCH), All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India ;
Dube D; d Department of Biophysics , All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India.
Kaur P; d Department of Biophysics , All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India.
Gupta R; a Laboratory Oncology Unit , Dr. Bhim Rao Ambedkar Institute Rotary Cancer Hospital (Dr. B.R.A.IRCH), All India Institute of Medical Sciences (AIIMS) , Ansari Nagar , New Delhi , India ;; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2016 Oct; Vol. 57 (10), pp. 2389-400. Date of Electronic Publication: 2016 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Mutation*
Genes, Immunoglobulin Heavy Chain/*genetics
Immunoglobulin Variable Region/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Receptors, Antigen, B-Cell/*genetics
Adult ; Aged ; Aged, 80 and over ; Complementarity Determining Regions/genetics ; DNA Mutational Analysis ; Disease Progression ; Female ; Gene Expression ; Gene Rearrangement, B-Lymphocyte ; Humans ; India ; Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis ; Leukemia, Lymphocytic, Chronic, B-Cell/mortality ; Leukemia, Lymphocytic, Chronic, B-Cell/therapy ; Male ; Middle Aged ; Multigene Family ; Neoplasm Staging ; Prognosis ; Time-to-Treatment

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Skocz do pozycji: 6.

Tytuł:: Exploiting biological diversity and genomic aberrations in chronic lymphocytic leukemia.
Autorzy:: Seiffert M; Division of Molecular Genetics, German Cancer Research Center, Heidelberg, Germany.
Dietrich S
Jethwa A
Glimm H
Lichter P
Zenz T; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2012 Jun; Vol. 53 (6), pp. 1023-31. Date of Electronic Publication: 2011 Dec 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Chromosome Aberrations*
Genetic Heterogeneity*
Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*therapy
Medical Oncology/*trends
Animals ; Biodiversity ; Genes, Immunoglobulin Heavy Chain/genetics ; Genome, Human/genetics ; Humans ; Models, Biological ; Molecular Targeted Therapy/methods ; Molecular Targeted Therapy/trends ; Tumor Microenvironment/genetics ; Tumor Microenvironment/physiology

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Skocz do pozycji: 7.

Tytuł:: Importance of immunoglobulin heavy chain variable region mutational status in del(13q) chronic lymphocytic leukemia.
Autorzy:: Gladstone DE; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA. />Swinnen L
Kasamon Y
Blackford A
Gocke CD
Griffin CA
Meade JB
Jones RJ; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2011 Oct; Vol. 52 (10), pp. 1873-81. Date of Electronic Publication: 2011 Aug 18.
Typ publikacji:: Journal Article
MeSH Terms:: Chromosome Deletion*
Mutation*
Chromosomes, Human, Pair 13/*genetics
Genes, Immunoglobulin Heavy Chain/*genetics
Immunoglobulin Variable Region/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Aged ; Chromosome Aberrations ; Female ; Follow-Up Studies ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/mortality ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Survival Analysis

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Skocz do pozycji: 8.

Tytuł:: Multi-parameter prognostication in chronic lymphocytic leukemia.
Autorzy:: Zent CS; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA.; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2011 Oct; Vol. 52 (10), pp. 1823-4. Date of Electronic Publication: 2011 Jul 08.
Typ publikacji:: Journal Article; Comment
MeSH Terms:: Chromosome Deletion*
Mutation*
Chromosomes, Human, Pair 13/*genetics
Genes, Immunoglobulin Heavy Chain/*genetics
Immunoglobulin Variable Region/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Female ; Humans ; Male

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Skocz do pozycji: 9.

Tytuł:: In a patient with biclonal Waldenstrom macroglobulinemia only one clone expands in three-dimensional culture and includes putative cancer stem cells.
Autorzy:: Kirshner J; Department of Oncology, University of Alberta and Cross Cancer Institute, Edmonton, Alberta, Canada.
Thulien KJ
Kriangkum J
Motz S
Belch AR
Pilarski LM; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2011 Feb; Vol. 52 (2), pp. 285-9. Date of Electronic Publication: 2010 Dec 06.
Typ publikacji:: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Lineage*
Gene Rearrangement, B-Lymphocyte, Heavy Chain/*genetics
Genes, Immunoglobulin Heavy Chain/*genetics
Neoplastic Stem Cells/*pathology
Waldenstrom Macroglobulinemia/*genetics
Aged ; B-Lymphocytes/pathology ; Cell Culture Techniques ; Clone Cells ; Colony-Forming Units Assay ; Female ; Humans ; Immunoglobulin M/genetics ; RNA, Messenger/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Cells, Cultured

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Skocz do pozycji: 10.

Tytuł:: Chronic lymphocytic leukemia in a Japanese population: varied immunophenotypic profile, distinctive usage of frequently mutated IGH gene, and indolent clinical behavior.
Autorzy:: Tomomatsu J; Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan.
Isobe Y
Oshimi K
Tabe Y
Ishii K
Noguchi M
Hirano T
Komatsu N
Sugimoto K; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2010 Dec; Vol. 51 (12), pp. 2230-9. Date of Electronic Publication: 2010 Nov 11.
Typ publikacji:: Journal Article
MeSH Terms:: Immunophenotyping*
Leukemia, Lymphocytic, Chronic, B-Cell/*diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*immunology
Oncogene Proteins, Fusion/*genetics
Adult ; Aged ; Aged, 80 and over ; Asian People ; Disease Progression ; Female ; Gene Frequency ; Genes, Immunoglobulin Heavy Chain/genetics ; Genes, bcl-2/genetics ; Humans ; Immunoglobulin Variable Region/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell/epidemiology ; Male ; Middle Aged ; Mutation ; Oncogene Proteins, Fusion/analysis ; Population ; Prognosis

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Skocz do pozycji: 11.

Tytuł:: Molecular and clinical features of chronic lymphocytic leukemia with stereotyped B-cell receptors in a Ukrainian cohort.
Autorzy:: Bilous N; Research Center for Radiation Medicine, Academy of Medical Sciences, Kiev, 04053, Ukraine. />Bomben R
Dal Bo M
Capello D
Forconi F
Laurenti L
Bertoni F
Efremov DG
Marasca R
Del Poeta G
Martina Z
Kryachouk I
Dyagil I
Gaidano G
Chumak A
Gattei V
Abramenko I; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2010 May; Vol. 51 (5), pp. 822-38.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*pathology
Receptors, Antigen, B-Cell/*genetics
Cohort Studies ; Complementarity Determining Regions/genetics ; Gene Rearrangement, B-Lymphocyte/genetics ; Genes, Immunoglobulin Heavy Chain/genetics ; Humans ; Immunoglobulin Variable Region/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy ; Somatic Hypermutation, Immunoglobulin/genetics ; Survival Rate ; Treatment Outcome

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Skocz do pozycji: 12.

Tytuł:: Combinations of ZAP-70, CD38 and IGHV mutational status as predictors of time to first treatment in CLL.
Autorzy:: Morilla A; Section of Haemato-Oncology, The Institute of Cancer Research, Sutton, Surrey, UK.
Gonzalez de Castro D
Del Giudice I
Osuji N
Else M
Morilla R
Brito Babapulle V
Rudenko H
Matutes E
Dearden C
Catovsky D
Morgan GJ; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2008 Nov; Vol. 49 (11), pp. 2108-15.
Typ publikacji:: Evaluation Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:: Mutation*
Predictive Value of Tests*
ADP-ribosyl Cyclase 1/*genetics
Genes, Immunoglobulin Heavy Chain/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*diagnosis
ZAP-70 Protein-Tyrosine Kinase/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers/analysis ; Female ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/genetics ; Male ; Middle Aged ; Prognosis

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Skocz do pozycji: 13.

Tytuł:: Serum thrombopoietin compared with ZAP-70 and immunoglobulin heavy-chain gene mutation status as a predictor of time to first treatment in early chronic lymphocytic leukemia.
Autorzy:: Molica S; Department of Oncology/Hematology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy. />Vitelli G
Cutrona G
Todoerti K
Mirabelli R
Digiesi G
Morabito F
Neri A
Ferrarini M; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2008 Jan; Vol. 49 (1), pp. 62-7.
Typ publikacji:: Journal Article
MeSH Terms:: Predictive Value of Tests*
Genes, Immunoglobulin Heavy Chain/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*diagnosis
Thrombopoietin/*blood
ZAP-70 Protein-Tyrosine Kinase/*blood
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Middle Aged ; Mutation ; Prognosis ; RNA, Messenger/blood ; Thrombopoietin/genetics

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Skocz do pozycji: 14.

Tytuł:: Evaluation of B-cell clonality in archival skin biopsy samples of cutaneous B-cell lymphoma by immunoglobulin heavy chain gene polymerase chain reaction.
Autorzy:: Lukowsky A; Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Germany. />Marchwat M
Sterry W
Gellrich S; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2006 Mar; Vol. 47 (3), pp. 487-93.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Rearrangement, B-Lymphocyte, Heavy Chain*
Genes, Immunoglobulin Heavy Chain/*genetics
Lymphoma, B-Cell/*diagnosis
Lymphoma, B-Cell/*genetics
Polymerase Chain Reaction/*methods
Skin Neoplasms/*diagnosis
Skin Neoplasms/*genetics
Biopsy ; Clone Cells ; DNA/genetics ; Humans ; Lymphoma, B-Cell/immunology ; Paraffin Embedding ; Sensitivity and Specificity ; Skin Neoplasms/immunology

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