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    Tytuł:
    Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases.
    Autorzy:
    Rosati E; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
    Pogorelyy MV; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Department of Translational Medicine, Pirogov Russian National Research Medical University [RNRMU], Moscow, Russian Federation.
    Dowds CM; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
    Moller FT; Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
    Sorensen SB; Focused Research Unit for Molecular Diagnostic and Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
    Lebedev YB; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.
    Frey N; Department of Internal Medicine III, University Hospital Schleswig-Holstein, Kiel, Germany.
    Schreiber S; Department of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany.
    Spehlmann ME; Department of Internal Medicine III, University Hospital Schleswig-Holstein, Kiel, Germany.
    Andersen V; Focused Research Unit for Molecular Diagnostic and Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; IRS-Center Sønderjylland, University of Southern Denmark, Odense, Denmark.
    Mamedov IZ; Laboratory of comparative and functional genomic, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russian Federation.; Department of Translational Medicine, Pirogov Russian National Research Medical University [RNRMU], Moscow, Russian Federation.; Laboratory of molecular biology, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.; CEITEC, Masaryk University, Brno, Czech Republic.
    Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
    Pokaż więcej
    Źródło:
    Journal of Crohn's & colitis [J Crohns Colitis] 2020 Jul 09; Vol. 14 (6), pp. 778-790.
    Typ publikacji:
    Journal Article; Twin Study
    MeSH Terms:
    Colitis, Ulcerative*/diagnosis
    Colitis, Ulcerative*/immunology
    Colitis, Ulcerative*/physiopathology
    Crohn Disease*/diagnosis
    Crohn Disease*/immunology
    Crohn Disease*/physiopathology
    Genes, T-Cell Receptor alpha*
    Genes, T-Cell Receptor beta*
    Receptors, Antigen, T-Cell, alpha-beta/*blood
    Adult ; C-Reactive Protein/analysis ; Denmark ; Feces ; Female ; Germany ; Humans ; Leukocyte L1 Antigen Complex/analysis ; Male ; Patient Acuity ; Sequence Analysis, DNA ; Smoking/immunology ; Twins, Monozygotic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis.
    Autorzy:
    Watson CT; Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
    Para AE
    Lincoln MR
    Ramagopalan SV
    Orton SM
    Morrison KM
    Handunnetthi L
    Handel AE
    Chao MJ
    Morahan J
    Sadovnick AD
    Breden F
    Ebers GC
    Pokaż więcej
    Źródło:
    Genes and immunity [Genes Immun] 2011 Mar; Vol. 12 (2), pp. 59-66. Date of Electronic Publication: 2011 Jan 27.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Genes, T-Cell Receptor alpha*
    Genes, T-Cell Receptor delta*
    Multiple Sclerosis/*genetics
    Multiple Sclerosis/*immunology
    Receptors, Antigen, T-Cell, alpha-beta/*genetics
    Receptors, Antigen, T-Cell, gamma-delta/*genetics
    Cohort Studies ; Genetic Predisposition to Disease ; Genotype ; Humans ; Polymorphism, Single Nucleotide ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; T-Lymphocytes/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Monomorphic epitheliotropic intestinal T-cell lymphoma with T-cell receptor (TCR) of silent phenotype shows rearrangement of TCRβ or TCRγ gene.
    Autorzy:
    Tomita S; Department of Pathology, Tokai University School of Medicine, Isehara, Japan.
    Kikuti YY; Department of Pathology, Tokai University School of Medicine, Isehara, Japan.
    Carreras J; Department of Pathology, Tokai University School of Medicine, Isehara, Japan.
    Nakamura N; Department of Pathology, Tokai University School of Medicine, Isehara, Japan.
    Pokaż więcej
    Źródło:
    Pathology international [Pathol Int] 2019 Feb; Vol. 69 (2), pp. 117-118. Date of Electronic Publication: 2018 Dec 21.
    Typ publikacji:
    Letter
    MeSH Terms:
    Enteropathy-Associated T-Cell Lymphoma/*genetics
    Genes, T-Cell Receptor alpha/*genetics
    Genes, T-Cell Receptor beta/*genetics
    Adult ; Aged ; Gene Rearrangement ; Humans ; Male ; Middle Aged ; Phenotype
    Opinia redakcyjna
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Clonal expanded TRA and TRB subfamily T cells in peripheral blood from patients with diffuse large B-cell lymphoma.
    Autorzy:
    Tan H; Centre of Oncology and Hematology, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510230, China. />Ye J
    Luo X
    Chen S
    Yin Q
    Yang L
    Li Y
    Pokaż więcej
    Źródło:
    Hematology (Amsterdam, Netherlands) [Hematology] 2010 Apr; Vol. 15 (2), pp. 81-7.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor*
    Gene Rearrangement, beta-Chain T-Cell Antigen Receptor*
    Genes, T-Cell Receptor alpha*
    Genes, T-Cell Receptor beta*
    Clone Cells/*pathology
    Lymphoma, Large B-Cell, Diffuse/*blood
    T-Lymphocyte Subsets/*pathology
    Adult ; Aged, 80 and over ; Antigens, Neoplasm/immunology ; DNA, Complementary/genetics ; Gene Expression Profiling ; Humans ; Lymphoma, Large B-Cell, Diffuse/immunology ; Lymphoma, Large B-Cell, Diffuse/pathology ; Male ; Middle Aged ; RNA, Messenger/genetics ; RNA, Neoplasm/genetics ; Receptors, Antigen, T-Cell, alpha-beta/analysis ; T-Cell Antigen Receptor Specificity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Numerical modelling of the V-J combinations of the T cell receptor TRA/TRD locus.
    Autorzy:
    Thuderoz F; CNRS, Laboratoire TIMC-IMAG, UMR 5525, Grenoble, France.
    Simonet MA
    Hansen O
    Pasqual N
    Dariz A
    Baum TP
    Hierle V
    Demongeot J
    Marche PN
    Jouvin-Marche E
    Pokaż więcej
    Źródło:
    PLoS computational biology [PLoS Comput Biol] 2010 Feb 19; Vol. 6 (2), pp. e1000682. Date of Electronic Publication: 2010 Feb 19.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genes, T-Cell Receptor alpha*
    Genes, T-Cell Receptor delta*
    Models, Immunological*
    Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor/*genetics
    Receptors, Antigen, T-Cell, alpha-beta/*genetics
    Animals ; Computer Simulation ; Gene Rearrangement, delta-Chain T-Cell Antigen Receptor/genetics ; Mice ; Mice, Inbred BALB C ; Reproducibility of Results
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Identification of new loci controlling collagen-induced arthritis in mouse using a partial advanced intercross and congenic strains.
    Autorzy:
    Popovic M; Medical Inflammation Research, Karolinska Institute, Stockholm, Sweden.
    Ahlqvist E
    Rockenbauer E
    Bockermann R
    Holmdahl R
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    Źródło:
    Scandinavian journal of immunology [Scand J Immunol] 2008 Oct; Vol. 68 (4), pp. 405-13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosome Mapping*
    Genes, T-Cell Receptor alpha*
    Genetic Predisposition to Disease*
    Arthritis, Experimental/*genetics
    Animals ; Chromosomes, Mammalian/genetics ; Female ; Male ; Mice ; Mice, Congenic ; Polymerase Chain Reaction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Long-term phenotypic, functional and genetic stability of cancer-specific T-cell receptor (TCR) alphabeta genes transduced to CD8+ T cells.
    Autorzy:
    Hiasa A; Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Mie, Japan.
    Hirayama M
    Nishikawa H
    Kitano S
    Nukaya I
    Yu SS
    Mineno J
    Kato I
    Shiku H
    Pokaż więcej
    Źródło:
    Gene therapy [Gene Ther] 2008 May; Vol. 15 (9), pp. 695-9. Date of Electronic Publication: 2008 Feb 21.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genes, T-Cell Receptor alpha*
    Genes, T-Cell Receptor beta*
    Adoptive Transfer/*methods
    CD8-Positive T-Lymphocytes/*immunology
    Genetic Therapy/*methods
    Transduction, Genetic/*methods
    Cell Line, Tumor ; Cells, Cultured ; Cloning, Molecular ; Cytotoxicity Tests, Immunologic ; Humans ; Immunophenotyping ; Interferon-gamma/immunology ; Lymphocyte Activation ; Melanoma/immunology ; Melanoma/therapy ; Retroviridae/genetics ; T-Cell Antigen Receptor Specificity ; Time
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Susceptibility of T cell receptor-alpha chain knock-out mice to ultraviolet B light and fluorouracil: a novel model for drug-induced cutaneous lupus erythematosus.
    Autorzy:
    Yoshimasu T; Department of Dermatology, Wakayama Medical University, Wakayama, Japan.
    Nishide T
    Seo N
    Hiroi A
    Ohtani T
    Uede K
    Furukawa F
    Pokaż więcej
    Źródło:
    Clinical and experimental immunology [Clin Exp Immunol] 2004 May; Vol. 136 (2), pp. 245-54.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genes, T-Cell Receptor alpha*
    Antineoplastic Agents/*adverse effects
    Fluorouracil/*adverse effects
    Lupus Erythematosus, Cutaneous/*immunology
    Skin/*immunology
    Ultraviolet Rays/*adverse effects
    Animals ; Dose-Response Relationship, Drug ; Gene Deletion ; Genes, T-Cell Receptor delta ; Interferon-gamma/immunology ; Interleukin-12/immunology ; Interleukin-2/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Th1 Cells/immunology ; Tumor Necrosis Factor-alpha/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Immunotherapy through TCR gene transfer.
    Autorzy:
    Kessels HW; Division of Immunology, Department of Experimental Animal Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
    Wolkers MC
    van den Boom MD
    van der Valk MA
    Schumacher TN
    Pokaż więcej
    Źródło:
    Nature immunology [Nat Immunol] 2001 Oct; Vol. 2 (10), pp. 957-61.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genes, T-Cell Receptor alpha*
    Genes, T-Cell Receptor beta*
    Genetic Therapy*
    Immunotherapy, Adoptive*
    Neoplasms, Experimental/*therapy
    T-Lymphocytes, Cytotoxic/*transplantation
    Animals ; Autoimmune Diseases/pathology ; Cell Movement ; Cells, Cultured ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Orthomyxoviridae Infections/immunology ; T-Lymphocytes, Cytotoxic/immunology ; Transduction, Genetic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Molecular mechanisms of cooperative binding of transcription factors Runx1-CBFβ-Ets1 on the TCRα gene enhancer.
    Autorzy:
    Kasahara K; College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan.
    Shiina M; Graduate School of Medicine, Yokohama City University, Kanazawa-ku, Yokohama, Kanagawa, Japan.
    Fukuda I; Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
    Ogata K; Graduate School of Medicine, Yokohama City University, Kanazawa-ku, Yokohama, Kanagawa, Japan.
    Nakamura H; Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2017 Feb 23; Vol. 12 (2), pp. e0172654. Date of Electronic Publication: 2017 Feb 23 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Molecular Dynamics Simulation*
    Core Binding Factor Alpha 2 Subunit/*metabolism
    Core Binding Factor beta Subunit/*metabolism
    Genes, T-Cell Receptor alpha/*genetics
    Proto-Oncogene Protein c-ets-1/*metabolism
    Core Binding Factor Alpha 2 Subunit/genetics ; Core Binding Factor beta Subunit/genetics ; Humans ; Nucleic Acid Conformation ; Phosphorylation ; Protein Binding ; Proto-Oncogene Protein c-ets-1/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Disturbance in the Mucosa-Associated Commensal Bacteria Is Associated with the Exacerbation of Chronic Colitis by Repeated Psychological Stress; Is That the New Target of Probiotics?
    Autorzy:
    Arase S; Yakult Central Institute, Kunitachi-shi, Tokyo, Japan.
    Watanabe Y; Yakult Central Institute, Kunitachi-shi, Tokyo, Japan.
    Setoyama H; Yakult Central Institute, Kunitachi-shi, Tokyo, Japan.
    Nagaoka N; Yakult Central Institute, Kunitachi-shi, Tokyo, Japan.
    Kawai M; Yakult Central Institute, Kunitachi-shi, Tokyo, Japan.
    Matsumoto S; Yakult Central Institute, Kunitachi-shi, Tokyo, Japan.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2016 Aug 08; Vol. 11 (8), pp. e0160736. Date of Electronic Publication: 2016 Aug 08 (Print Publication: 2016).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Disease Models, Animal*
    Colitis/*etiology
    Genes, T-Cell Receptor alpha/*genetics
    Intestinal Mucosa/*microbiology
    Lactobacillus/*growth & development
    Probiotics/*administration & dosage
    Stress, Psychological/*complications
    Animals ; Chronic Disease ; Colitis/psychology ; Female ; Intestinal Mucosa/immunology ; Intestinal Mucosa/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; RNA, Ribosomal, 16S/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire.
    Autorzy:
    Dashtsoodol N; Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.; Core Research Laboratory, Mongolian National University of Medical Sciences (MNUMS), Ulaanbaatar, 14210, Mongolia.
    Shigeura T; Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.
    Ozawa R; Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.
    Harada M; Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.
    Kojo S; Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.
    Watanabe T; Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.
    Koseki H; Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.
    Nakayama M; Department of Human Genome Research, Kazusa DNA Research Institute, Kisarazu, Chiba, 292-0818, Japan.
    Ohara O; Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.
    Taniguchi M; Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2016 Apr 11; Vol. 11 (4), pp. e0153347. Date of Electronic Publication: 2016 Apr 11 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor/*immunology
    Genes, T-Cell Receptor alpha/*physiology
    Killer Cells, Natural/*immunology
    Liver Neoplasms/*immunology
    Melanoma, Experimental/*immunology
    Animals ; Flow Cytometry ; Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor/genetics ; Liver Neoplasms/metabolism ; Liver Neoplasms/secondary ; Melanoma, Experimental/metabolism ; Melanoma, Experimental/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Real-Time Polymerase Chain Reaction ; T-Lymphocyte Subsets/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.
    Autorzy:
    Klarenbeek PL; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Laboratory for Genome Analysis, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
    Doorenspleet ME; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Laboratory for Genome Analysis, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
    Esveldt RE; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
    van Schaik BD; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, University of Amsterdam, Amsterdam, The Netherlands.
    Lardy N; Department of Immunogenetics, Sanquin Diagnostic Services, Amsterdam, The Netherlands.
    van Kampen AH; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, University of Amsterdam, Amsterdam, The Netherlands.
    Tak PP; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
    Plenge RM; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.
    Baas F; Laboratory for Genome Analysis, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
    de Bakker PI; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America; Department of Epidemiology, University Medical Center, Utrecht, The Netherlands; Department of Medical Genetics, University Medical Center, Utrecht, The Netherlands.
    de Vries N; Department of Clinical Immunology and Rheumatology, Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2015 Oct 30; Vol. 10 (10), pp. e0140815. Date of Electronic Publication: 2015 Oct 30 (Print Publication: 2015).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Genes, T-Cell Receptor/*genetics
    HLA Antigens/*genetics
    CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Cell Differentiation/genetics ; Cell Lineage/genetics ; Genes, T-Cell Receptor alpha/genetics ; Genes, T-Cell Receptor beta/genetics ; Genetic Variation ; Humans ; Receptors, Antigen, T-Cell/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Regulatory T cells in B-cell-deficient and wild-type mice differ functionally and in expression of cell surface markers.
    Autorzy:
    Ellis JS; Department of Medicine, University of Missouri, Columbia, MO, USA; Department of Molecular Microbiology & Immunology, University of Missouri, Columbia, MO, USA.
    Braley-Mullen H
    Pokaż więcej
    Źródło:
    Immunology [Immunology] 2015 Apr; Vol. 144 (4), pp. 598-610.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    B-Lymphocytes/*immunology
    T-Lymphocytes, Regulatory/*immunology
    Thyroiditis, Autoimmune/*immunology
    Adoptive Transfer ; Animals ; B-Lymphocytes/metabolism ; Biomarkers/metabolism ; Bone Marrow Transplantation ; CD28 Antigens/deficiency ; CD28 Antigens/genetics ; Cell Communication ; Cells, Cultured ; Coculture Techniques ; Disease Models, Animal ; Genes, T-Cell Receptor alpha ; Genetic Predisposition to Disease ; Leukocyte Common Antigens/genetics ; Mice, Inbred NOD ; Mice, Knockout ; Phenotype ; Severity of Illness Index ; T-Lymphocytes, Regulatory/metabolism ; T-Lymphocytes, Regulatory/transplantation ; Thyroiditis, Autoimmune/genetics ; Thyroiditis, Autoimmune/metabolism ; Thyroiditis, Autoimmune/prevention & control ; Transplantation Chimera
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days.
    Autorzy:
    Kobayashi E; 1] Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan. [2].
    Mizukoshi E
    Kishi H
    Ozawa T
    Hamana H
    Nagai T
    Nakagawa H
    Jin A
    Kaneko S
    Muraguchi A
    Pokaż więcej
    Źródło:
    Nature medicine [Nat Med] 2013 Nov; Vol. 19 (11), pp. 1542-6. Date of Electronic Publication: 2013 Oct 13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Validation Study
    MeSH Terms:
    Genes, T-Cell Receptor*
    Cloning, Molecular/*methods
    Neoplasms/*genetics
    Neoplasms/*immunology
    Antigens, Neoplasm/metabolism ; Cancer Vaccines/genetics ; Cancer Vaccines/immunology ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/immunology ; Carcinoma, Hepatocellular/therapy ; Gene Expression ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor beta ; Genetic Therapy ; Herpesvirus 4, Human/immunology ; Humans ; Immunotherapy ; Liver Neoplasms/genetics ; Liver Neoplasms/immunology ; Liver Neoplasms/therapy ; Molecular Sequence Data ; Neoplasms/therapy ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; T-Lymphocytes, Cytotoxic/immunology ; alpha-Fetoproteins/genetics ; alpha-Fetoproteins/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Phage display of functional αβ single-chain T-cell receptor molecules specific for CD1b:Ac₂SGL complexes from Mycobacterium tuberculosis-infected cells.
    Autorzy:
    Camacho F; Finlay Institute, Havana, Cuba.
    Huggett J
    Kim L
    Infante JF
    Lepore M
    Perez V
    Sarmiento ME
    Rook G
    Acosta A
    Pokaż więcej
    Źródło:
    BMC immunology [BMC Immunol] 2013; Vol. 14 Suppl 1, pp. S2. Date of Electronic Publication: 2013 Feb 25.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cell Surface Display Techniques*
    Antigens, Bacterial/*immunology
    Antigens, CD1/*immunology
    Glycolipids/*immunology
    Mycobacterium tuberculosis/*immunology
    Receptors, Antigen, T-Cell, alpha-beta/*immunology
    Tuberculosis/*immunology
    Bacteriophage M13 ; Cell Line ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor beta ; Humans ; Lung/immunology ; Lung/microbiology ; Lymphocyte Activation ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Recombinant Fusion Proteins/immunology ; Viral Proteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Analysis of the paired TCR α- and β-chains of single human T cells.
    Autorzy:
    Kim SM; Department of Dermatology, Ludwig-Maximilian-University, Munich, Germany.
    Bhonsle L
    Besgen P
    Nickel J
    Backes A
    Held K
    Vollmer S
    Dornmair K
    Prinz JC
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2012; Vol. 7 (5), pp. e37338. Date of Electronic Publication: 2012 May 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Validation Study
    MeSH Terms:
    Genes, T-Cell Receptor alpha/*genetics
    Genes, T-Cell Receptor beta/*genetics
    Multiplex Polymerase Chain Reaction/*methods
    Reverse Transcriptase Polymerase Chain Reaction/*methods
    T-Lymphocytes/*metabolism
    Antigen-Presenting Cells/immunology ; DNA Primers/genetics ; Flow Cytometry ; Humans ; Multiple Sclerosis/immunology ; Psoriasis/immunology ; Skin/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Polysaccharides isolated from Açaí fruit induce innate immune responses.
    Autorzy:
    Holderness J; Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America.
    Schepetkin IA
    Freedman B
    Kirpotina LN
    Quinn MT
    Hedges JF
    Jutila MA
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2011 Feb 28; Vol. 6 (2), pp. e17301. Date of Electronic Publication: 2011 Feb 28.
    Typ publikacji:
    Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Arecaceae/*chemistry
    Fruit/*chemistry
    Immunity, Innate/*drug effects
    Polysaccharides/*isolation & purification
    Polysaccharides/*pharmacology
    Animals ; Cattle ; Cells, Cultured ; Genes, T-Cell Receptor alpha ; Humans ; Immunity, Innate/genetics ; Immunity, Innate/physiology ; Lymphocyte Activation/drug effects ; Mice ; Mice, Inbred C3H ; Mice, Inbred C57BL ; Mice, Knockout ; Myeloid Differentiation Factor 88/genetics ; Phenols/pharmacology ; Toll-Like Receptor 4/genetics ; Up-Regulation/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.
    Autorzy:
    Kirak O; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. />Frickel EM
    Grotenbreg GM
    Suh H
    Jaenisch R
    Ploegh HL
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2010 Apr 09; Vol. 328 (5975), pp. 243-8.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mice, Transgenic*
    Nuclear Transfer Techniques*
    Antigens, Protozoan/*immunology
    Receptors, Antigen, T-Cell, alpha-beta/*immunology
    Toxoplasma/*immunology
    Toxoplasmosis, Animal/*immunology
    Animals ; CD8-Positive T-Lymphocytes/immunology ; Embryonic Stem Cells ; Epitopes, T-Lymphocyte ; Female ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor beta ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Molecular Sequence Data ; Protozoan Proteins/genetics ; Protozoan Proteins/immunology ; Receptors, Antigen, T-Cell, alpha-beta/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Rapid and reliable generation of invariant natural killer T-cell lines in vitro.
    Autorzy:
    Chiba A; Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
    Cohen N
    Brigl M
    Brennan PJ
    Besra GS
    Brenner MB
    Pokaż więcej
    Źródło:
    Immunology [Immunology] 2009 Nov; Vol. 128 (3), pp. 324-33.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cell Line*
    Cytokines/*metabolism
    Dendritic Cells/*metabolism
    Galactosylceramides/*immunology
    Natural Killer T-Cells/*metabolism
    Animals ; Antigens, CD1/genetics ; Antigens, CD1/immunology ; Cell Culture Techniques ; Cell Proliferation ; Cytokines/immunology ; Dendritic Cells/immunology ; Genes, T-Cell Receptor alpha/genetics ; Genes, T-Cell Receptor beta/genetics ; Mice ; Mice, Knockout ; Mice, Transgenic ; Natural Killer T-Cells/cytology ; Natural Killer T-Cells/immunology ; Spleen/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    53BP1 facilitates long-range DNA end-joining during V(D)J recombination.
    Autorzy:
    Difilippantonio S; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1360, USA.
    Gapud E
    Wong N
    Huang CY
    Mahowald G
    Chen HT
    Kruhlak MJ
    Callen E
    Livak F
    Nussenzweig MC
    Sleckman BP
    Nussenzweig A
    Pokaż więcej
    Źródło:
    Nature [Nature] 2008 Nov 27; Vol. 456 (7221), pp. 529-33. Date of Electronic Publication: 2008 Oct 19.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Recombination, Genetic*
    DNA/*metabolism
    Gene Rearrangement, T-Lymphocyte/*genetics
    Intracellular Signaling Peptides and Proteins/*metabolism
    Animals ; Apoptosis ; Chromosomal Proteins, Non-Histone ; DNA/genetics ; DNA Breaks ; DNA-Binding Proteins ; Genes, T-Cell Receptor alpha/genetics ; Genomic Instability ; Intracellular Signaling Peptides and Proteins/deficiency ; Intracellular Signaling Peptides and Proteins/genetics ; Lymphopenia/genetics ; Lymphopenia/pathology ; Mice ; Models, Genetic ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; Sequence Homology ; T-Lymphocytes/cytology ; T-Lymphocytes/metabolism ; Thymus Gland/cytology ; Tumor Suppressor p53-Binding Protein 1
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes.
    Autorzy:
    Skok JA; Department of Immunology and Molecular Pathology, Division of Infection and Immunity, University College London, London W1T 4JF, UK.
    Gisler R
    Novatchkova M
    Farmer D
    de Laat W
    Busslinger M
    Pokaż więcej
    Źródło:
    Nature immunology [Nat Immunol] 2007 Apr; Vol. 8 (4), pp. 378-87. Date of Electronic Publication: 2007 Mar 04.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Rearrangement, T-Lymphocyte/*immunology
    Genes, T-Cell Receptor alpha/*immunology
    Genes, T-Cell Receptor beta/*immunology
    Genes, T-Cell Receptor delta/*immunology
    T-Lymphocytes/*immunology
    Animals ; Cell Differentiation ; DNA-Binding Proteins/immunology ; Immunoglobulin Constant Regions/immunology ; Immunoglobulin Variable Region/immunology ; In Situ Hybridization, Fluorescence ; Lymphopoiesis/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Microscopy, Confocal ; PAX5 Transcription Factor/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Analysis of the CDR3 region of alpha/beta T-cell receptors (TCRs) and TCR BD gene double-stranded recombination signal sequence breaks end in peripheral blood mononuclear cells of T-lineage acute lymphoblastic leukemia.
    Autorzy:
    Xin-Sheng Y; Institute of Molecular Immunology, Southern Medical University, Guangzhou 510515, China.
    Zheng-Jun X
    Li M
    Wan-Bang S
    Wei-Yang Z
    Qian W
    Zhi-Ming H
    Min-Jie M
    Ying L
    Zhen-Qiang W
    Xiao-Wei H
    Ju-Fang W
    Xiao-Ning W
    Pokaż więcej
    Źródło:
    Clinical and laboratory haematology [Clin Lab Haematol] 2006 Dec; Vol. 28 (6), pp. 405-15.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Complementarity Determining Regions/*genetics
    Genes, T-Cell Receptor alpha/*genetics
    Genes, T-Cell Receptor beta/*genetics
    Leukemia-Lymphoma, Adult T-Cell/*genetics
    Receptors, Antigen, T-Cell/*genetics
    Adolescent ; Adult ; Case-Control Studies ; Cells, Cultured ; Clone Cells ; Humans ; Leukemia-Lymphoma, Adult T-Cell/blood ; Leukemia-Lymphoma, Adult T-Cell/immunology ; Male ; Receptors, Antigen, T-Cell/chemistry ; Receptors, Antigen, T-Cell, alpha-beta/chemistry ; Recombination, Genetic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Regulation of T cell receptor-alpha gene recombination by transcription.
    Autorzy:
    Abarrategui I; Department of Immunology, Duke University Medical Center, Durham, North Carolina 27710, USA.
    Krangel MS
    Pokaż więcej
    Źródło:
    Nature immunology [Nat Immunol] 2006 Oct; Vol. 7 (10), pp. 1109-15. Date of Electronic Publication: 2006 Aug 27.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Recombination, Genetic*
    Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor/*genetics
    Genes, T-Cell Receptor alpha/*genetics
    Transcription, Genetic/*genetics
    Animals ; Chromatin Assembly and Disassembly ; Immunoglobulin Joining Region/genetics ; Mice ; Mice, Mutant Strains ; Promoter Regions, Genetic ; Sequence Deletion
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCRbeta locus rearrangements and putative new T-cell oncogenes.
    Autorzy:
    Cauwelier B; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium. />Dastugue N
    Cools J
    Poppe B
    Herens C
    De Paepe A
    Hagemeijer A
    Speleman F
    Pokaż więcej
    Źródło:
    Leukemia [Leukemia] 2006 Jul; Vol. 20 (7), pp. 1238-44. Date of Electronic Publication: 2006 May 04.
    Typ publikacji:
    Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Rearrangement, T-Lymphocyte/*genetics
    Genes, T-Cell Receptor beta/*genetics
    Leukemia-Lymphoma, Adult T-Cell/*epidemiology
    Leukemia-Lymphoma, Adult T-Cell/*genetics
    Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Genes, T-Cell Receptor alpha/genetics ; Genes, T-Cell Receptor delta/genetics ; Humans ; In Situ Hybridization, Fluorescence ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; Translocation, Genetic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Partial cloning of the T-cell receptor-alpha gene and assignment of TRA and TRB genes to the catfish linkage map.
    Autorzy:
    Karsi A; USDA-ARS Catfish Genetics Research Unit, Thad Cochran National Warmwater Aquaculture Center, PO Box 38, Stoneville, MS 38776, USA.
    Waldbieser GC
    Pokaż więcej
    Źródło:
    Animal genetics [Anim Genet] 2004 Apr; Vol. 35 (2), pp. 150-1.
    Typ publikacji:
    Comparative Study; Journal Article
    MeSH Terms:
    Chromosome Mapping*
    Polymorphism, Genetic*
    Catfishes/*genetics
    Genes, T-Cell Receptor alpha/*genetics
    Genes, T-Cell Receptor beta/*genetics
    Animals ; Base Sequence ; Chromosomes, Artificial, Bacterial ; DNA Primers ; Microsatellite Repeats/genetics ; Molecular Sequence Data ; Sequence Analysis, DNA
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Development of humanized mice as a model of inflammatory arthritis.
    Autorzy:
    Sønderstrup G; Department of Microbiology and Immunology, Stanford University School of Medicine, Sherman Fairchild Building D345, 299 Campus Drive, Stanford, CA 94305-5124, USA.
    Pokaż więcej
    Źródło:
    Springer seminars in immunopathology [Springer Semin Immunopathol] 2003 Aug; Vol. 25 (1), pp. 35-45.
    Typ publikacji:
    Journal Article; Research Support, U.S. Gov't, P.H.S.; Review
    MeSH Terms:
    Disease Models, Animal*
    Mice, Transgenic*
    Arthritis, Rheumatoid/*immunology
    Autoantibodies/*immunology
    Autoantigens/*immunology
    Adipokines ; Animals ; Arthritis, Rheumatoid/etiology ; Arthritis, Rheumatoid/pathology ; CD4-Positive T-Lymphocytes/immunology ; Chitinase-3-Like Protein 1 ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor beta ; Glycoproteins ; Histocompatibility Antigens Class II/immunology ; Humans ; Lectins/immunology ; Mice ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Tumor Necrosis Factor-alpha/immunology ; Tumor Necrosis Factor-alpha/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Immunosuppressive treatments for myelodysplastic syndromes.
    Autorzy:
    Shimamoto T; First Department of Internal Medicine, Tokyo Medical University, 6-7-1, Nishishinjuku, Shinjuku-ku Tokyo 160-0023, Japan. />Ohyashiki K
    Pokaż więcej
    Źródło:
    Leukemia & lymphoma [Leuk Lymphoma] 2003 Apr; Vol. 44 (4), pp. 593-604.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Immunosuppressive Agents/*therapeutic use
    Myelodysplastic Syndromes/*therapy
    Autoimmune Diseases/complications ; Blotting, Southern ; CD4 Antigens/biosynthesis ; CD8 Antigens/biosynthesis ; Cell Lineage ; Clinical Trials as Topic ; Cyclosporine/pharmacology ; Gene Rearrangement ; Genes, T-Cell Receptor alpha ; Humans ; Karyotyping ; Models, Biological ; Pilot Projects ; Receptors, Antigen, T-Cell, gamma-delta
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Different role of Apaf-1 in positive selection, negative selection and death by neglect in foetal thymic organ culture.
    Autorzy:
    Matsuki Y; Department of Immulogy and Parasitology, National Defense Medical College, Saitama, Japan.
    Zhang HG
    Hsu HC
    Yang PA
    Zhou T
    Dodd CH
    Cecconi F
    Gruss P
    Tadakuma T
    Mountz JD
    Pokaż więcej
    Źródło:
    Scandinavian journal of immunology [Scand J Immunol] 2002 Aug; Vol. 56 (2), pp. 174-84.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Proteins/*immunology
    Thymus Gland/*embryology
    Animals ; Apoptosis/immunology ; Apoptotic Protease-Activating Factor 1 ; Autoimmunity ; Female ; Fetus/cytology ; Fetus/immunology ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor beta ; Male ; Mice ; Mice, Knockout ; Mice, Transgenic ; Organ Culture Techniques ; Proteins/genetics ; T-Lymphocyte Subsets/cytology ; T-Lymphocyte Subsets/immunology ; Thymus Gland/cytology ; Thymus Gland/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The unconventional lifestyle of NKT cells.
    Autorzy:
    Kronenberg M; La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, California 92121, USA. />Gapin L
    Pokaż więcej
    Źródło:
    Nature reviews. Immunology [Nat Rev Immunol] 2002 Aug; Vol. 2 (8), pp. 557-68.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
    MeSH Terms:
    Antigens, CD1/*immunology
    Genes, T-Cell Receptor alpha/*immunology
    Killer Cells, Natural/*immunology
    Animals ; Antigens, CD1d ; Humans ; Immunoglobulin Variable Region/immunology ; Interferon-gamma/immunology ; Interleukin-4/immunology ; Mice ; Mice, Transgenic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Identification of ricin A-chain HLA class II-restricted epitopes by human T-cell clones.
    Autorzy:
    Tommasi M; Section of Immunology, Department of Pathology, University of Verona, Italy.
    Castelletti D
    Pasti M
    Fracasso G
    Lorenzetti I
    Sartoris S
    Pera C
    Ferrara GB
    Tridente G
    Colombatti M
    Pokaż więcej
    Źródło:
    Clinical and experimental immunology [Clin Exp Immunol] 2001 Sep; Vol. 125 (3), pp. 391-400.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    HLA-DR Antigens/*immunology
    Ricin/*immunology
    T-Lymphocytes/*immunology
    Amino Acid Sequence ; Clone Cells ; Epitopes ; Genes, T-Cell Receptor alpha ; HLA-DR3 Antigen/immunology ; HLA-DRB1 Chains ; Humans ; Immunotoxins ; Molecular Sequence Data ; Peptide Fragments/immunology ; T-Lymphocytes, Helper-Inducer ; Vaccination
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Assessing a role for enhancer-blocking activity in gene regulation within the murine T-cell receptor alpha/delta locus.
    Autorzy:
    Sleckman BP; Department of Pathology, Washington University School of Medicine, St Louis, MO, USA.
    Carabana J
    Zhong X
    Krangel MS
    Pokaż więcej
    Źródło:
    Immunology [Immunology] 2001 Sep; Vol. 104 (1), pp. 11-8.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Enhancer Elements, Genetic/*genetics
    Gene Expression Regulation, Developmental/*immunology
    Genes, T-Cell Receptor alpha/*genetics
    Genes, T-Cell Receptor delta/*genetics
    Animals ; Blotting, Northern ; Blotting, Southern ; Cell Differentiation/immunology ; Enhancer Elements, Genetic/immunology ; Gene Targeting ; Mice ; Mice, Transgenic ; Spleen/immunology ; Thymus Gland/immunology ; Transfection
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Assessment of the nucleotide sequence variability in the bovine T-cell receptor alpha delta joining gene region.
    Autorzy:
    Fries R; Lehrstuhl für Tierzucht, Technische Universität München, Freising, Germany. />Ewald D
    Thaller G
    Buitkamp J
    Pokaż więcej
    Źródło:
    Animal biotechnology [Anim Biotechnol] 2001 May; Vol. 12 (1), pp. 29-49.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Phylogeny*
    Polymorphism, Single Nucleotide*
    Cattle/*genetics
    Genes, T-Cell Receptor alpha/*genetics
    Genes, T-Cell Receptor delta/*genetics
    Immunoglobulin Joining Region/*genetics
    Alleles ; Animals ; Base Sequence ; Enzyme-Linked Immunosorbent Assay ; Haplotypes ; Humans ; Male ; Mice/genetics ; Molecular Sequence Data ; Polymorphism, Genetic ; Sequence Analysis, DNA
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Perspectives: transcription. A tail of histone acetylation and DNA recombination.
    Autorzy:
    Schlissel MS; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3200, USA.
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2000 Jan 21; Vol. 287 (5452), pp. 438-40.
    Typ publikacji:
    Comment; Journal Article
    MeSH Terms:
    Gene Rearrangement*
    Genes, Immunoglobulin*
    Genes, T-Cell Receptor*
    Recombination, Genetic*
    Saccharomyces cerevisiae Proteins*
    Histones/*metabolism
    Acetylation ; Acetyltransferases/metabolism ; Chromatin/metabolism ; DNA Nucleotidyltransferases/metabolism ; Enhancer Elements, Genetic ; Gene Rearrangement, T-Lymphocyte ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor delta ; Histone Acetyltransferases ; Nucleosomes/chemistry ; Nucleosomes/ultrastructure ; Transcription Factors ; Transcription, Genetic ; VDJ Recombinases
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors.
    Autorzy:
    Cui J; Core Research for Evolutional Science and Technology (CREST) Project, Japan Science and Technology Corporation (JST), 1-8-1 Inohana, Chuo-ku, Chiba, Japan 260.
    Shin T
    Kawano T
    Sato H
    Kondo E
    Toura I
    Kaneko Y
    Koseki H
    Kanno M
    Taniguchi M
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 1997 Nov 28; Vol. 278 (5343), pp. 1623-6.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cytotoxicity, Immunologic*
    Macrolides*
    Interleukin-12/*immunology
    Killer Cells, Natural/*immunology
    Neoplasms, Experimental/*immunology
    Receptors, Antigen, T-Cell, alpha-beta/*immunology
    T-Lymphocyte Subsets/*immunology
    Animals ; Anti-Bacterial Agents/pharmacology ; Gene Deletion ; Gene Targeting ; Genes, RAG-1 ; Genes, T-Cell Receptor alpha ; Interferon-gamma/immunology ; Melanoma, Experimental/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Poly I-C/pharmacology ; Proton-Translocating ATPases/antagonists & inhibitors ; Receptors, Antigen, T-Cell, alpha-beta/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-38 z 38

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