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Wyszukujesz frazę ""Genes, erbB-2"" wg kryterium: Temat


Tytuł :
Antimetastatic and Antitumor Activities of Orally Administered NAX014 Compound in a Murine Model of HER2-Positive Breast Cancer.
Autorzy :
Pierpaoli E; Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.
Piacenza F; Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.
Fiorillo G; Naxospharma Srl, 20026 Novate Milanese, Italy.
Lombardi P; Naxospharma Srl, 20026 Novate Milanese, Italy.
Orlando F; Experimental Animal Models for Aging Unit, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.
Salvatore C; Aesis Therapeutics Srl, Incubatore JCube, 60035 Jesi, Italy.
Geroni C; Aesis Therapeutics Srl, Incubatore JCube, 60035 Jesi, Italy.
Provinciali M; Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.; Experimental Animal Models for Aging Unit, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 06; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 06.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, erbB-2*
Antineoplastic Agents/*therapeutic use
Berberine Alkaloids/*therapeutic use
Mammary Neoplasms, Experimental/*prevention & control
Neoplasm Metastasis/*prevention & control
Administration, Oral ; Animals ; Antineoplastic Agents/administration & dosage ; Berberine Alkaloids/administration & dosage ; Berberine Alkaloids/chemistry ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Drug Screening Assays, Antitumor ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Mammary Neoplasms, Experimental/drug therapy ; Mammary Neoplasms, Experimental/genetics ; Mice ; Mice, Transgenic ; Molecular Structure ; Neoplasm Metastasis/drug therapy ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/genetics ; Rats ; Tumor Burden/drug effects
Czasopismo naukowe
Tytuł :
The fragility of a structurally diverse duplication block triggers recurrent genomic amplification.
Autorzy :
Suzuki R; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Murata MM; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Manguso N; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Watanabe T; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Mouakkad-Montoya L; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Igari F; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Rahman MM; Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
Qu Y; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Cui X; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Giuliano AE; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Takeda S; Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
Tanaka H; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 11; Vol. 49 (1), pp. 244-256.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
DNA Repair*
Gene Amplification*
Genes, erbB-2*
Breast Neoplasms/*genetics
Chromosome Fragile Sites/*genetics
Gene Duplication/*genetics
Keratins, Hair-Specific/*physiology
Aphidicolin/pharmacology ; Breast/metabolism ; Breast Neoplasms/metabolism ; Cells, Cultured ; Chromosomal Instability ; DNA Breaks ; DNA Copy Number Variations ; DNA, Neoplasm/genetics ; Epithelial Cells/metabolism ; Female ; Genetic Variation ; Genomic Instability ; Humans ; MRE11 Homologue Protein/physiology ; Neoplasm Proteins/physiology ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
CDK12 and HER2 coamplification in two urothelial carcinomas with rapid and aggressive clinical progression.
Autorzy :
Yanai Y; Department of Urology, Keio University School of Medicine, Tokyo, Japan.
Kosaka T; Department of Urology, Keio University School of Medicine, Tokyo, Japan.
Nakamura K; Genomics Unit, Keio Cancer Center, Keio University School of Medicine, Tokyo, Japan.
Aimono E; Genomics Unit, Keio Cancer Center, Keio University School of Medicine, Tokyo, Japan.
Matsumoto K; Department of Urology, Keio University School of Medicine, Tokyo, Japan.
Morita S; Department of Urology, Keio University School of Medicine, Tokyo, Japan.
Mikami S; Department of Diagnostic Pathology, Keio University School of Medicine, Tokyo, Japan.
Nishihara H; Genomics Unit, Keio Cancer Center, Keio University School of Medicine, Tokyo, Japan.
Oya M; Department of Urology, Keio University School of Medicine, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2020 Dec; Vol. 111 (12), pp. 4652-4655. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Case Reports
MeSH Terms :
Gene Amplification*
Genes, erbB-2*
Cyclin-Dependent Kinases/*genetics
Kidney Neoplasms/*genetics
Urinary Bladder Neoplasms/*genetics
Adenocarcinoma/genetics ; Adenocarcinoma/therapy ; Aged ; Aged, 80 and over ; Carcinoma, Transitional Cell/genetics ; Carcinoma, Transitional Cell/therapy ; Disease Progression ; Fatal Outcome ; Genes, p53 ; Humans ; Kidney Neoplasms/therapy ; Male ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/therapy ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/therapy
Raport
Tytuł :
HER2 gene assessment in liquid biopsy of gastric and esophagogastric junction cancer patients qualified for surgery.
Autorzy :
Grenda A; Chair and Department of Pneumology, Oncology and Allergology, Medical University of Lublin, Jaczewskiego 8, 20-090, Lublin, Poland. .
Wojas-Krawczyk K; Chair and Department of Pneumology, Oncology and Allergology, Medical University of Lublin, Jaczewskiego 8, 20-090, Lublin, Poland.
Skoczylas T; II Chair and Department of General and Gastrointestinal Surgery and Surgical Oncology of the Alimentary Tract, Medical University of Lublin, Staszica 16, 20-080, Lublin, Poland.
Krawczyk P; Chair and Department of Pneumology, Oncology and Allergology, Medical University of Lublin, Jaczewskiego 8, 20-090, Lublin, Poland.
Sierocińska-Sawa J; Laboratory of Pathomorphology, Independent Public Clinical Hospital No. 1 in Lublin, ul. Staszica 11, 20-081, Lublin, Poland.
Wallner G; II Chair and Department of General and Gastrointestinal Surgery and Surgical Oncology of the Alimentary Tract, Medical University of Lublin, Staszica 16, 20-080, Lublin, Poland.
Milanowski J; Chair and Department of Pneumology, Oncology and Allergology, Medical University of Lublin, Jaczewskiego 8, 20-090, Lublin, Poland.
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Źródło :
BMC gastroenterology [BMC Gastroenterol] 2020 Nov 16; Vol. 20 (1), pp. 382. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, erbB-2*
Stomach Neoplasms*/genetics
Stomach Neoplasms*/surgery
Biomarkers, Tumor ; DNA Copy Number Variations ; Esophagogastric Junction ; Gene Amplification ; Humans ; In Situ Hybridization, Fluorescence ; Liquid Biopsy ; Receptor, ErbB-2/genetics
Czasopismo naukowe
Tytuł :
Peroxisome proliferator-activated receptor ɑ (PPARɑ)-cytochrome P450 epoxygenases-soluble epoxide hydrolase axis in ER + PR + HER2- breast cancer.
Autorzy :
Tauber Z; Department of Histology and Embryology, Faculty of Medicine and Dentistry, Palacky University, Hněvotínská 3, 779 00, Olomouc, Czech Republic.
Koleckova M; Laboratory of Molecular Pathology, Department of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University, Hněvotínská 3, 779 00, Olomouc, Czech Republic.
Cizkova K; Department of Histology and Embryology, Faculty of Medicine and Dentistry, Palacky University, Hněvotínská 3, 779 00, Olomouc, Czech Republic. .
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Źródło :
Medical molecular morphology [Med Mol Morphol] 2020 Sep; Vol. 53 (3), pp. 141-148. Date of Electronic Publication: 2019 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, erbB-2*
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
Cytochrome P-450 Enzyme System/*metabolism
Epoxide Hydrolases/*metabolism
PPAR alpha/*metabolism
Receptors, Estrogen/*metabolism
Receptors, Progesterone/*metabolism
Animals ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Female ; Fibric Acids/pharmacology ; Humans ; Inhibitory Concentration 50 ; Ki-67 Antigen/metabolism ; MCF-7 Cells ; Protein Transport/drug effects ; Pyrimidines/pharmacology ; Solubility ; Subcellular Fractions/metabolism
Czasopismo naukowe
Tytuł :
HER2 as a potential biomarker of lymph node metastasis in undifferentiated early gastric cancer.
Autorzy :
Han S; Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.
Park S; College of Medicine, Gachon University, Incheon, Republic of Korea.; Gachon Institute of Genome Medicine and Science, Gachon University Gil Medical Center, Incheon, Republic of Korea.
An J; Department of Pathology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
Yang JY; Department of Surgery, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
Chung JW; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
Kim YJ; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
Kim KO; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
Park DK; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
Kwon KA; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
Lee WK; Department of Surgery, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
Nam S; College of Medicine, Gachon University, Incheon, Republic of Korea. .; Gachon Institute of Genome Medicine and Science, Gachon University Gil Medical Center, Incheon, Republic of Korea. .; Department of Life Sciences, Gachon University, Seongnam, Republic of Korea. .; Gachon Advanced Institute of Health Sciences & Technology, Gachon University, Incheon, Republic of Korea. .
Kim JH; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea. .; Gachon Medical Research Institute, Gachon University Gil Medical Center, Incheon, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 24; Vol. 10 (1), pp. 5270. Date of Electronic Publication: 2020 Mar 24.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, erbB-2*
Adenocarcinoma/*secondary
Lymphatic Metastasis/*genetics
Neoplasm Proteins/*physiology
Receptor, ErbB-2/*physiology
Stomach Neoplasms/*pathology
Adenocarcinoma/genetics ; Adenocarcinoma/surgery ; Aged ; Biomarkers, Tumor ; Cell Differentiation ; Datasets as Topic ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lymph Node Excision ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/genetics ; Receptor, ErbB-2/biosynthesis ; Receptor, ErbB-2/genetics ; Retrospective Studies ; Stomach Neoplasms/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Decision of adjuvant chemotherapy in intermediate risk luminal breast cancer patients: A prospective multicenter trial assessing the clinical and psychological impact of EndoPredict® (EpClin) use (UCBG 2-14).
Autorzy :
Penault-Llorca F; Université Clermont Auvergne, Centre Jean Perrin, Department of Biology and Pathology, INSERM, U1240 Imagerie Moléculaire et Stratégies Théranostiques, Clermont Ferrand, France.
Kwiatkowski F; Université Clermont Auvergne, Centre Jean Perrin, Department of Biostatistics, INSERM, U1240 Imagerie Moléculaire et Stratégies Théranostiques, Clermont Ferrand, France.
Arnaud A; Department of Medical Oncology, Institut Sainte Catherine, Avignon, France.
Levy C; Department of Medical Oncology, Centre François Baclesse, Caen, France.
Leheurteur M; Department of Medical Oncology, Centre Henri Becquerel, Rouen, France.
Uwer L; Department of Medical Oncology, Institut de Cancérologie de Lorraine, Vandoeuvre Les Nancy, France.
Derbel O; Department of Medical Oncology, Hôpital Privé Jean Mermoz, Lyon, France.
Le Rol A; Department of Medical Oncology, Centre Hospitalier Intercommunal, Quimper, France.
Jacquin JP; Department of Medical Oncology, Institut de Cancérologie Lucien Newirth, Saint Priest en Jarez, France.
Jouannaud C; Department of Medical Oncology, Institut Jean Godinot, Reims, France.
Quenel-Tueux N; Department of Medical Oncology, Institut Bergonié, Bordeaux, France.
Girre V; Department of Medical Oncology, Centre Hospitalier Départemental de Vendée, La Roche sur Yon, France.
Foa C; Department of Medical Oncology, Hôpital Saint Joseph, Marseille, France.
Guardiola E; Department of Medical Oncology, Centre Hospitalier de La Dracénie, Draguignan, France.
Lortholary A; Department of Medical Oncology, Centre Catherine de Sienne, Nantes, France.
Catala S; Department of Medical Oncology, Centre Catalan D'oncologie, Perpignan, France.
Guiu S; Department of Medical Oncology, Institut Régional Du Cancer Montpellier (ICM), Val D'Aurelle, Montpellier, France.
Valent A; Department of Biopathology, Gustave Roussy, Villejuif, France.
Boinon D; Department of Supportive Care, Psycho-oncology Unit, Gustave Roussy, Villejuif, France.
Lemonnier J; R&D UNICANCER, Paris, France.
Delaloge S; Department of Medical Oncology, Gustave Roussy, Villejuif, France. Electronic address: .
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Źródło :
Breast (Edinburgh, Scotland) [Breast] 2020 Feb; Vol. 49, pp. 132-140. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study
MeSH Terms :
Clinical Decision Rules*
Genes, erbB-2*
Breast Neoplasms/*drug therapy
Clinical Decision-Making/*methods
Genetic Testing/*methods
Receptors, Estrogen/*genetics
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Anxiety/diagnosis ; Anxiety/etiology ; Breast Neoplasms/genetics ; Breast Neoplasms/psychology ; Breast Neoplasms/surgery ; Chemotherapy, Adjuvant ; Female ; Genetic Markers ; Genomics ; Humans ; Mastectomy ; Middle Aged ; Patient Reported Outcome Measures ; Prospective Studies ; Psychological Distress ; Risk Assessment ; Uncertainty
Czasopismo naukowe
Tytuł :
Multigene PCR using both cfDNA and cfRNA in the supernatant of pleural effusion achieves accurate and rapid detection of mutations and fusions of driver genes in patients with advanced NSCLC.
Autorzy :
Chen X; Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China.
Li K; Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China.
Liu Z; Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China.
Gai F; Medical Department, Amoy Diagnostics Co., Ltd., Xiamen, China.
Zhu G; Medical Department, Amoy Diagnostics Co., Ltd., Xiamen, China.
Lu S; Department of Oncology, Shanghai Chest Hospital Shanghai Jiaotong University, Shanghai, China.
Che N; Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China.
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Źródło :
Cancer medicine [Cancer Med] 2021 Apr; Vol. 10 (7), pp. 2286-2292. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Fusion*
Mutation*
Carcinoma, Non-Small-Cell Lung/*genetics
Cell-Free Nucleic Acids/*genetics
Lung Neoplasms/*genetics
Pleural Effusion, Malignant/*genetics
Anaplastic Lymphoma Kinase/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; DNA, Neoplasm ; Female ; Genes, erbB-1 ; Genes, erbB-2 ; Genes, ras ; Humans ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Pleural Effusion, Malignant/pathology ; Polymerase Chain Reaction/methods ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Non-amplification genetic alterations of HER2 gene in non-small cell lung carcinoma.
Autorzy :
Mehta A; Deapartment of Laboratory Medicine, Transfusion Services and Molecular Diagnostics, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India .
Nathany S; Section of Molecular Diagnostics, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Tripathi R; Department of Research, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Sharma SK; Section of Molecular Diagnostics, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Saifi M; Section of Molecular Diagnostics, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
Batra U; Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2021 Feb; Vol. 74 (2), pp. 106-110. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma of Lung/*genetics
Lung Neoplasms/*genetics
Receptor, ErbB-2/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Female ; Genes, erbB-2 ; Humans ; Male ; Middle Aged ; Mutation ; Young Adult
Czasopismo naukowe
Tytuł :
Aptasensor based on screen-printed electrode for breast cancer detection in undiluted human serum.
Autorzy :
Ferreira DC; Department of Physics, Faculty of Philosophy, Sciences and Letters, University of São Paulo, 14040-901, Ribeirão Preto, SP, Brazil.
Batistuti MR; Department of Physics, Faculty of Philosophy, Sciences and Letters, University of São Paulo, 14040-901, Ribeirão Preto, SP, Brazil. Electronic address: .
Bachour B Junior; Department of Physics, Faculty of Philosophy, Sciences and Letters, University of São Paulo, 14040-901, Ribeirão Preto, SP, Brazil.
Mulato M; Department of Physics, Faculty of Philosophy, Sciences and Letters, University of São Paulo, 14040-901, Ribeirão Preto, SP, Brazil.
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Źródło :
Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2021 Feb; Vol. 137, pp. 107586. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Electrodes*
Aptamers, Nucleotide/*chemistry
Breast Neoplasms/*diagnosis
Electrochemical Techniques/*instrumentation
Biomarkers, Tumor ; Biosensing Techniques/methods ; Breast Neoplasms/blood ; Female ; Genes, erbB-2 ; Humans ; Limit of Detection
Czasopismo naukowe
Tytuł :
QnAs with H. Michael Shepard and Dennis J. Slamon.
Autorzy :
Davis TH
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 14; Vol. 117 (2), pp. 796-798. Date of Electronic Publication: 2019 Dec 30.
Typ publikacji :
Interview; Portrait
MeSH Terms :
Genes, erbB-2*
Receptor, ErbB-2*
Antibodies, Monoclonal/*therapeutic use
Neoplasms/*drug therapy
Biotechnology ; Humans
Tytuł :
ErbB1 and ErbB2 overexpression in patients with sinonasal inverted papilloma and inverted papilloma with squamous cell carcinoma in China.
Autorzy :
Li H; Department of Otolaryngology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Hu L; Department of Otolaryngology, Eye and ENT Hospital of Fudan University, Shanghai, China.; Department of Research Centre, Eye and ENT Hospital of Fudan University, Shanghai, China.
Zhang H; Department of Otolaryngology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Wang D; Department of Otolaryngology, Eye and ENT Hospital of Fudan University, Shanghai, China.
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Źródło :
Acta oto-laryngologica [Acta Otolaryngol] 2019 Dec; Vol. 139 (12), pp. 1104-1111. Date of Electronic Publication: 2019 Sep 26.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, erbB-1*
Genes, erbB-2*
ErbB Receptors/*metabolism
Papilloma, Inverted/*metabolism
Paranasal Sinus Neoplasms/*metabolism
Adult ; Aged ; Case-Control Studies ; China ; Female ; Humans ; Male ; Middle Aged ; Nasal Mucosa/pathology ; Papilloma, Inverted/genetics ; Papilloma, Inverted/pathology ; Paranasal Sinus Neoplasms/genetics ; Paranasal Sinus Neoplasms/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Validation of the AJCC prognostic stage for HER2-positive breast cancer in the ShortHER trial.
Autorzy :
Dieci MV; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.; Medical Oncology 2, Istituto Oncologico Veneto - IRCCS, Via Gattamelata 64, 35128, Padova, Italy.
Bisagni G; Department of Oncology and Advanced Technologies, Oncology Unit, Azienda USL-IRCCS, Reggio Emilia, Italy.
Brandes AA; Medical Oncology, Azienda Unità Sanitaria Locale di Bologna-IRCCS Istituto delle Scienze Neurologiche, Bologna, Italy.
Frassoldati A; Clinical Oncology, Department of Morphology, Surgery and Experimental Medicine, S Anna University Hospital, Ferrara, Italy.
Cavanna L; Department of Oncology-Hematology, G. da Saliceto Hospital, Piacenza, Italy.
Giotta F; IRCCS Istituto Tumori 'Giovanni Paolo II' di Bari, Bari, Italy.
Aieta M; Division of Medical Oncology, IRCCS-CROB, Referral Cancer Center of Basilicata, Rionero Vulture, Italy.
Gebbia V; Medical Oncology, Casa di Cura La Maddalena, University of Palermo, Palermo, Italy.
Musolino A; Medical Oncology Unit, University Hospital of Parma, Parma, Italy.
Garrone O; Medical Oncology, A.O. S. Croce and Carle Teaching Hospital, Cuneo, Italy.
Donadio M; Department of Medical Oncology 1, Città della Salute e della Scienza Hospital, Turin, Italy.
Rimanti A; Medical Oncology, Azienda Ospedaliera di Mantova, Mantova, Italy.
Beano A; Department of Medical Oncology 1, Città della Salute e della Scienza Hospital, Turin, Italy.
Zamagni C; Policlinico S.Orsola-Malpighi, SSD Oncologia Medica Addarii, Bologna, Italy.
Soto Parra H; Medical Oncology Unit, AOU Policlinico Vittorio Emanuele, Catania, Italy.
Piacentini F; Division of Medical Oncology Department of Medical and Surgical Sciences for Children & Adults, University Hospital of Modena, Modena, Italy.
Danese S; Department of Gynecology and Obstetrics, Ospedale S. Anna, Turin, Italy.
Ferro A; Rete clinica senologica - Oncologia medica S. Chiara, Trento, Italy.
Cagossi K; Breast Unit Ausl Modena, Ramazzini Hospital, Carpi, Italy.
Sarti S; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.
Gambaro AR; Oncology Unit, Luigi Sacco Hospital, Milan, Italy.
Romito S; Medical Oncology, A.O.U. 'Ospedali Riuniti', Foggia, Italy.
Bazan V; Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Palermo, Italy.
Amaducci L; Medical Oncology Unit, Ospedale degli Infermi Faenza, Faenza, Italy.
Moretti G; Department of Oncology and Advanced Technologies, Oncology Unit, Azienda USL-IRCCS, Reggio Emilia, Italy.
Foschini MP; Department of Biomedical and Neuromotor Sciences, University of Bologna, Unit of Anatomic Pathology at Bellaria Hospital, Bologna, Italy.
Balduzzi S; Department of Medical and Surgical Sciences for Children & Adults, University of Modena, Modena, Italy.
Vicini R; Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.
D'Amico R; Department of Medical and Surgical Sciences for Children & Adults, University of Modena, Modena, Italy.; Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.
Griguolo G; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.; Medical Oncology 2, Istituto Oncologico Veneto - IRCCS, Via Gattamelata 64, 35128, Padova, Italy.
Guarneri V; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.; Medical Oncology 2, Istituto Oncologico Veneto - IRCCS, Via Gattamelata 64, 35128, Padova, Italy.
Conte PF; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy. .; Medical Oncology 2, Istituto Oncologico Veneto - IRCCS, Via Gattamelata 64, 35128, Padova, Italy. .
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Źródło :
BMC medicine [BMC Med] 2019 Nov 21; Vol. 17 (1), pp. 207. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Genes, erbB-2*
Neoplasm Staging*
Antineoplastic Agents, Immunological/*therapeutic use
Breast Neoplasms/*diagnosis
Trastuzumab/*therapeutic use
Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Disease-Free Survival ; Female ; Humans ; Middle Aged ; Neoplasm Recurrence, Local ; Prognosis
Czasopismo naukowe
Tytuł :
KRAS, NRAS, BRAF, HER2 and microsatellite instability in metastatic colorectal cancer - practical implications for the clinician.
Autorzy :
Afrăsânie VA; 'Gr. T. Popa' University of Medicine and Pharmacy Iași, Iași, Romania.; Regional Institute of Oncology Iași, Iași, Romania.
Marinca MV; 'Gr. T. Popa' University of Medicine and Pharmacy Iași, Iași, Romania.; Regional Institute of Oncology Iași, Iași, Romania.
Alexa-Stratulat T; 'Gr. T. Popa' University of Medicine and Pharmacy Iași, Iași, Romania.; Regional Institute of Oncology Iași, Iași, Romania.
Gafton B; 'Gr. T. Popa' University of Medicine and Pharmacy Iași, Iași, Romania.; Regional Institute of Oncology Iași, Iași, Romania.
Păduraru M; 'Gr. T. Popa' University of Medicine and Pharmacy Iași, Iași, Romania.; Regional Institute of Oncology Iași, Iași, Romania.
Adavidoaiei AM; 'Gr. T. Popa' University of Medicine and Pharmacy Iași, Iași, Romania.
Miron L; 'Gr. T. Popa' University of Medicine and Pharmacy Iași, Iași, Romania.; Regional Institute of Oncology Iași, Iași, Romania.
Rusu C; 'Gr. T. Popa' University of Medicine and Pharmacy Iași, Iași, Romania.
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Źródło :
Radiology and oncology [Radiol Oncol] 2019 Sep 24; Vol. 53 (3), pp. 265-274. Date of Electronic Publication: 2019 Sep 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genes, erbB-2*
Genes, ras*
Microsatellite Instability*
Mutation*
Colorectal Neoplasms/*drug therapy
Colorectal Neoplasms/*genetics
Proto-Oncogene Proteins B-raf/*genetics
Antineoplastic Agents, Immunological/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cetuximab/therapeutic use ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/pathology ; ErbB Receptors/antagonists & inhibitors ; Female ; Genetic Markers ; Humans ; Ipilimumab/therapeutic use ; Male ; Panitumumab/therapeutic use ; Prognosis ; Sex Factors ; Trastuzumab/therapeutic use
Czasopismo naukowe
Tytuł :
Clinical efficacy of combination of pertuzumab, trastuzumab, and docetaxel for treatment of patients with HER2-positive breast cancer.
Autorzy :
Liu YC; Department of Anatomy.
Ma Y; Department of Library, Mudanjiang Medical University.
An N; Second Ward of Neurology Department, Affiliated Hongqi Hospital of Mudanjiang Medical University.
Sun P; Department of Anatomy.
Wang Y; Institute of Neuro Tissue Engineering, Mudanjiang Medical University, Mudanjiang, China.
Sun C; Department of Anatomy.
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Źródło :
Medicine [Medicine (Baltimore)] 2019 Sep; Vol. 98 (38), pp. e17262.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Genes, erbB-2*
Antibodies, Monoclonal, Humanized/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Breast Neoplasms/*drug therapy
Docetaxel/*therapeutic use
Receptor, ErbB-2/*metabolism
Trastuzumab/*therapeutic use
Antibodies, Monoclonal, Humanized/administration & dosage ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Docetaxel/administration & dosage ; Female ; Humans ; Trastuzumab/administration & dosage ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Her-2 Breast Cancer Outcomes Are Mitigated by Consuming n-3 Polyunsaturated, Saturated, and Monounsaturated Fatty Acids Compared to n-6 Polyunsaturated Fatty Acids.
Autorzy :
Hillyer LM; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Hucik B; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Baracuhy EM; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Lin Z; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Muller WJ; Department of Biochemistry, Rosalind and Morris Goodman Cancer Centre, McGill University, Montreal, QC H3A 1A3, Canada.
Robinson LE; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Ma DWL; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
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Źródło :
Nutrients [Nutrients] 2020 Dec 20; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 20.
Typ publikacji :
Journal Article
MeSH Terms :
Diet/*veterinary
Fatty Acids/*administration & dosage
Genes, erbB-2/*genetics
Mammary Neoplasms, Animal/*pathology
Animal Feed ; Animals ; Fatty Acids/classification ; Female ; Mammary Neoplasms, Animal/diet therapy ; Mammary Neoplasms, Animal/genetics ; Mice ; Mice, Transgenic ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Cancer of unknown primary.
Autorzy :
Lee MS; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sanoff HK; Division of Hematology/Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
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Źródło :
BMJ (Clinical research ed.) [BMJ] 2020 Dec 07; Vol. 371, pp. m4050. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Expression Profiling*
High-Throughput Nucleotide Sequencing*
Molecular Diagnostic Techniques*
Biomarkers, Tumor/*metabolism
Neoplasms, Unknown Primary/*diagnosis
Anaplastic Lymphoma Kinase/genetics ; Antineoplastic Agents/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biopsy ; Circulating Tumor DNA/genetics ; Genes, erbB-1 ; Genes, erbB-2 ; Humans ; Lymph Nodes/pathology ; Mammography ; Molecular Targeted Therapy ; Mutation ; Neoplasms, Unknown Primary/drug therapy ; Neoplasms, Unknown Primary/epidemiology ; Neoplasms, Unknown Primary/genetics ; Occult Blood ; Physical Examination ; Physical Functional Performance ; Positron Emission Tomography Computed Tomography ; Proto-Oncogene Proteins B-raf/genetics ; Real-Time Polymerase Chain Reaction ; Risk Assessment ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.
Autorzy :
Nachmanson D; Bioinformatics and Systems Biology Graduate Program - UC San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Steward J; Moores Cancer Center - UC San Diego Health - 3855 Health Sciences Dr., La Jolla, CA, 92093, USA.
Yao H; Institute for Genomic Medicine - UC San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Officer A; Bioinformatics and Systems Biology Graduate Program - UC San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, USA.; Division of Biomedical Informatics, Department of Medicine - UC San Diego School of Medicine, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Jeong E; Moores Cancer Center - UC San Diego Health - 3855 Health Sciences Dr., La Jolla, CA, 92093, USA.
O'Keefe TJ; Division of Breast Surgery and The Comprehensive Breast Health Center - UC San Diego School of Medicine, 3855 Health Sciences Dr., La Jolla, CA, 92093, USA.
Hasteh F; Department of Pathology - UC San Diego School of Medicine, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Jepsen K; Institute for Genomic Medicine - UC San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Hirst GL; Helen Diller Family Comprehensive Cancer Center - UC San Francisco School of Medicine, 1450 3rd St, San Francisco, CA, 94158, USA.
Esserman LJ; Helen Diller Family Comprehensive Cancer Center - UC San Francisco School of Medicine, 1450 3rd St, San Francisco, CA, 94158, USA.
Borowsky AD; Department of Pathology and Laboratory Medicine - UC Davis Comprehensive Cancer Center, UC Davis School of Medicine, 2279 45th Street, Sacramento, CA, 95817, USA.
Harismendy O; Moores Cancer Center - UC San Diego Health - 3855 Health Sciences Dr., La Jolla, CA, 92093, USA. .; Division of Biomedical Informatics, Department of Medicine - UC San Diego School of Medicine, 9500 Gilman Dr., La Jolla, CA, 92093, USA. .
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Źródło :
BMC medical genomics [BMC Med Genomics] 2020 Nov 18; Vol. 13 (1), pp. 173. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Specimen Banks*
Specimen Handling*
Breast Neoplasms/*genetics
Carcinoma, Intraductal, Noninfiltrating/*genetics
DNA Mutational Analysis/*methods
Sequence Analysis, DNA/*methods
Benchmarking ; Clone Cells ; DNA Copy Number Variations ; DNA Fragmentation ; Dissection/methods ; Female ; Gene Library ; Genes, erbB-2 ; Genetic Heterogeneity ; Humans ; INDEL Mutation ; Mutation ; Paraffin Embedding ; Polymorphism, Single Nucleotide ; Real-Time Polymerase Chain Reaction ; Tissue Fixation
Czasopismo naukowe
Tytuł :
Chromothripsis in Human Breast Cancer.
Autorzy :
Bolkestein M; Group Genome Instability in Tumors, DKFZ, Heidelberg, Germany.
Wong JKL; Division of Molecular Genetics, DKFZ; DKFZ-Heidelberg Center for Personalized Oncology (HIPO) and German Cancer Consortium (DKTK), Heidelberg, Germany.
Thewes V; Division of Molecular Genetics, DKFZ; DKFZ-Heidelberg Center for Personalized Oncology (HIPO) and German Cancer Consortium (DKTK), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), University Hospital and DKFZ, Heidelberg, Germany.
Körber V; Division of Theoretical Systems Biology, DKFZ, Heidelberg, Germany.
Hlevnjak M; Division of Molecular Genetics, DKFZ; DKFZ-Heidelberg Center for Personalized Oncology (HIPO) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Computational Oncology Group, Molecular Diagnostics Program at the National Center for Tumor Diseases (NCT) and DKFZ, Heidelberg, Germany.
Elgaafary S; National Center for Tumor Diseases (NCT), University Hospital and DKFZ, Heidelberg, Germany.; Molecular Diagnostics Program at the National Center for Tumor Diseases (NCT) and DKFZ, Heidelberg, Germany.
Schulze M; Division of Molecular Genetics, DKFZ; DKFZ-Heidelberg Center for Personalized Oncology (HIPO) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Computational Oncology Group, Molecular Diagnostics Program at the National Center for Tumor Diseases (NCT) and DKFZ, Heidelberg, Germany.
Kommoss FKF; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Sinn HP; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Anzeneder T; Patients' Tumor Bank of Hope (PATH), Munich, Germany.
Hirsch S; Institute of Human Genetics, Heidelberg University, Heidelberg, Germany.
Devens F; Group Genome Instability in Tumors, DKFZ, Heidelberg, Germany.
Schröter P; Division of Molecular Genetics, DKFZ; DKFZ-Heidelberg Center for Personalized Oncology (HIPO) and German Cancer Consortium (DKTK), Heidelberg, Germany.
Höfer T; Division of Theoretical Systems Biology, DKFZ, Heidelberg, Germany.
Schneeweiss A; National Center for Tumor Diseases (NCT), University Hospital and DKFZ, Heidelberg, Germany.
Lichter P; Division of Molecular Genetics, DKFZ; DKFZ-Heidelberg Center for Personalized Oncology (HIPO) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Molecular Diagnostics Program at the National Center for Tumor Diseases (NCT) and DKFZ, Heidelberg, Germany.
Zapatka M; Division of Molecular Genetics, DKFZ; DKFZ-Heidelberg Center for Personalized Oncology (HIPO) and German Cancer Consortium (DKTK), Heidelberg, Germany.
Ernst A; Group Genome Instability in Tumors, DKFZ, Heidelberg, Germany. .
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Źródło :
Cancer research [Cancer Res] 2020 Nov 15; Vol. 80 (22), pp. 4918-4931. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromothripsis*
Gene Rearrangement*
Breast Neoplasms/*genetics
Neoplasm Recurrence, Local/*genetics
Algorithms ; Chromosomes, Human, Pair 11 ; Chromosomes, Human, Pair 17 ; Cyclin D1/genetics ; Cyclin-Dependent Kinases/genetics ; DNA Repair ; Female ; Gene Fusion ; Genes, BRCA1 ; Genes, BRCA2 ; Genes, erbB-2 ; Genes, p53 ; Humans ; INDEL Mutation ; Signal Transduction ; Whole Exome Sequencing ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Protein Corona Gold Nanoparticles Fingerprinting Reveals a Profile of Blood Coagulation Proteins in the Serum of HER2-Overexpressing Breast Cancer Patients.
Autorzy :
Chantada-Vázquez MDP; Research Unit, Lucus Augusti University Hospital (HULA), Servizo Galego de Saúde (SERGAS), 27002 Lugo, Spain.; Proteomic Unit, Health Research Institute of Santiago de Compostela (IDIS), University Clinical Hospital of Santiago de Compostela (CHUS), 15706 Santiago de Compostela, Spain.
Castro López A; Breast Unit, Hospital Universitario Lucus Augusti (HULA), Servizo Galego de Saúde (SERGAS), 27002 Lugo, Spain.
García-Vence M; Proteomic Unit, Health Research Institute of Santiago de Compostela (IDIS), University Clinical Hospital of Santiago de Compostela (CHUS), 15706 Santiago de Compostela, Spain.
Acea-Nebril B; Department of Surgery, Breast Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), Servizo Galego de Saúde (SERGAS), 15006 A Coruña, Spain.
Bravo SB; Proteomic Unit, Health Research Institute of Santiago de Compostela (IDIS), University Clinical Hospital of Santiago de Compostela (CHUS), 15706 Santiago de Compostela, Spain.
Núñez C; Research Unit, Lucus Augusti University Hospital (HULA), Servizo Galego de Saúde (SERGAS), 27002 Lugo, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 10; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Coagulation Factors/*metabolism
Breast Neoplasms/*blood
Breast Neoplasms/*metabolism
Peptide Mapping/*methods
Receptor, ErbB-2/*metabolism
Biomarkers, Tumor/blood ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/classification ; Case-Control Studies ; Female ; Genes, erbB-2 ; Gold ; Humans ; Mass Spectrometry ; Metal Nanoparticles ; Protein Corona ; Receptor, ErbB-2/genetics ; Triple Negative Breast Neoplasms/blood ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism
Czasopismo naukowe

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