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Tytuł:
Validation of Dual-Color Dual In Situ Hybridization for HER2/neu Gene in Breast Cancer.
Autorzy:
Rathi A; From the Department of Pathology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.
Sahay A; From the Department of Pathology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.
Shet TM; From the Department of Pathology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.
Patil A; From the Department of Pathology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.
Desai SB; From the Department of Pathology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2024 Apr 01; Vol. 148 (4), pp. 453-460.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, erbB-2*
Breast Neoplasms*/diagnosis
Humans ; Female ; In Situ Hybridization, Fluorescence/methods ; Reproducibility of Results ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; Immunohistochemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A gene expression-based classifier for HER2-low breast cancer.
Autorzy:
Di Cosimo S; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Pizzamiglio S; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy. .
Ciniselli CM; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Duroni V; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Cappelletti V; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
De Cecco L; Molecular Mechanisms Unit, Department of Research, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
De Marco C; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Silvestri M; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
De Santis MC; Radiation Oncology 1, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.; Breast Unit, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Vingiani A; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.; Breast Unit, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Paolini B; Department of Pathology, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Orlandi R; Molecular Targeting Unit, Department of Research, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Iorio MV; Molecular Targeting Unit, Department of Research, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Pruneri G; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.; Breast Unit, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Verderio P; Bioinformatics and Biostatistics Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 01; Vol. 14 (1), pp. 2628. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Humans ; Female ; Receptor, ErbB-2/metabolism ; Genes, erbB-2 ; Immunohistochemistry ; Gene Expression ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Upregulated Expression of ERBB2/HER2 in Multiple Myeloma as a Predictor of Poor Survival Outcomes.
Autorzy:
Uckun FM; Immuno-Oncology Program, Ares Pharmaceuticals, St. Paul, MN 55110, USA.
Qazi S; Immuno-Oncology Program, Ares Pharmaceuticals, St. Paul, MN 55110, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 09; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Myeloma*/genetics
Breast Neoplasms*/genetics
Humans ; Female ; Genes, erbB-2 ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Treatment Outcome ; Base Sequence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Vitro and In Vivo Effects of the Combination of Polypurine Reverse Hoogsteen Hairpins against HER-2 and Trastuzumab in Breast Cancer Cells.
Autorzy:
López-Aguilar E; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Universitat de Barcelona (UB), 08028 Barcelona, Spain.
Fernández-Nogueira P; Unit of Biophysics and Bioengineering, Department of Biomedicine, School of Medicine and Health Sciences, Universitat de Barcelona (UB), 08028 Barcelona, Spain.; Department of Biochemistry and Molecular Biomedicine, School of Biology, Universitat de Barcelona (UB), 08028 Barcelona, Spain.
Fuster G; Department of Biochemistry and Molecular Biomedicine, School of Biology, Universitat de Barcelona (UB), 08028 Barcelona, Spain.; Tissue Repair and Regeneration Laboratory (TR2Lab), Institut de Recerca i Innovació en Ciències de la Vida i de la Salut a la Catalunya Central (IrisCC), 08500 Vic, Spain.; Department of Biosciences, Faculty of Sciences, Technology and Engineering, Universitat de Vic-Universitat Central de Catalunya (UVic-UCC), 08500 Vic, Spain.; Institute of Biomedicine, Universitat de Barcelona (IBUB), 08028 Barcelona, Spain.
Carbó N; Department of Biochemistry and Molecular Biomedicine, School of Biology, Universitat de Barcelona (UB), 08028 Barcelona, Spain.; Institute of Biomedicine, Universitat de Barcelona (IBUB), 08028 Barcelona, Spain.
Ciudad CJ; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Universitat de Barcelona (UB), 08028 Barcelona, Spain.; Institute of Nanoscience and Nanotechnology, Universitat de Barcelona (IN2UB), 08028 Barcelona, Spain.
Noé V; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Universitat de Barcelona (UB), 08028 Barcelona, Spain.; Institute of Nanoscience and Nanotechnology, Universitat de Barcelona (IN2UB), 08028 Barcelona, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 11; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, erbB-2*
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Humans ; Female ; Trastuzumab/pharmacology ; Trastuzumab/genetics ; Oncogenes ; MCF-7 Cells ; RNA, Messenger/genetics ; Cell Line, Tumor ; Receptor, ErbB-2/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Establishment and evaluation of digital PCR methods for HER2 copy number variation in breast cancer.
Autorzy:
Wang X; Center for Advanced Measurement Science, National Institute of Metrology, Beijing, China.
Xing D; Center for Advanced Measurement Science, National Institute of Metrology, Beijing, China.
Liu Z; Center for Advanced Measurement Science, National Institute of Metrology, Beijing, China.
Zhang Y; Center for Advanced Measurement Science, National Institute of Metrology, Beijing, China.
Cheng B; Chinese People's Liberation Army Rocket Force Characteristic Medical Center, Beijing, China.
Sun S; Chinese People's Liberation Army Rocket Force Characteristic Medical Center, Beijing, China.
Wang Q; Beijing Chaoyang Hospital, the Third Clinical Medical College of Capital Medical University, Beijing, China.
Dong L; Center for Advanced Measurement Science, National Institute of Metrology, Beijing, China. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2023 Feb; Vol. 415 (4), pp. 725-733. Date of Electronic Publication: 2022 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/pathology
Humans ; Female ; DNA Copy Number Variations ; In Situ Hybridization, Fluorescence ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; Polymerase Chain Reaction/methods ; Genes, erbB-2
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Expression and Clinical Significance of HER2 Gene and DNMT1 in Non-Small-Cell Lung Cancer.
Autorzy:
Diao W; Department of Pathology, The First Affiliated Hospital of Jiamusi University, China.
Ding C; Department of Pathology, The First Affiliated Hospital of Jiamusi University, China.
Yuan B; Department of Acupuncture and Mimoxibustion, The First Affiliated Hospital of Jiamusi University, China.
Li Z; Department of Analytical Chemistry Teaching and Research, Jiamusi University, China.
Sun N; Graduate Department, Jiamusi University, China.
Huang J; Department of Geratology, The First Affiliated Hospital of Jiamusi University, China.
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Źródło:
Disease markers [Dis Markers] 2022 Aug 13; Vol. 2022, pp. 8426384. Date of Electronic Publication: 2022 Aug 13 (Print Publication: 2022).
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
DNA (Cytosine-5-)-Methyltransferase 1*/genetics
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Receptor, ErbB-2*/genetics
Genes, erbB-2 ; Humans ; Lymphatic Metastasis ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Novel miRNA Located in the HER2 Gene Shows an Inhibitory Effect on Wnt Signaling and Cell Cycle Progression.
Autorzy:
Shabaninejad Z; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Mowla SJ; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Yousefi F; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Soltani BM; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Jun 14; Vol. 2022, pp. 7216758. Date of Electronic Publication: 2022 Jun 14 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
Cell Cycle/genetics ; Cell Division ; Cell Line, Tumor ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Genes, erbB-2 ; HEK293 Cells ; HeLa Cells ; Humans ; Wnt Signaling Pathway/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study.
Autorzy:
Kawakami S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Takano S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan. .
Fukasawa M; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Shindo H; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Takahashi E; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Fukasawa Y; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Hayakawa H; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kuratomi N; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kadokura M; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Hosomura N; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Amemiya H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Kawaida H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Kono H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Maekawa S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Ichikawa D; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Enomoto N; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
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Źródło:
BMC cancer [BMC Cancer] 2021 Nov 19; Vol. 21 (1), pp. 1245. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji:
Journal Article
MeSH Terms:
Mutation*
Gallbladder Neoplasms/*genetics
Genes, p53/*genetics
Pancreaticobiliary Maljunction/*genetics
Adult ; Aged ; Case-Control Studies ; Cholecystitis/genetics ; Female ; Gene Expression Profiling ; Genes, Retinoblastoma ; Genes, erbB-1 ; Genes, erbB-2 ; Genes, ras ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Mutation Accumulation ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
HER-2 positivity is a high risk of recurrence of stage I gastric cancer
Autorzy:
Seonhoo Kim
Yeon-Ji Kim
Woo Chul Chung
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Temat:
stomach neoplasms
recurrence
genes erbb-2
Medicine
Źródło:
The Korean Journal of Internal Medicine, Vol 36, Iss 6, Pp 1327-1337 (2021)
Opis pliku:
electronic resource
Relacje:
http://www.kjim.org/upload/pdf/kjim-2020-243.pdf; https://doaj.org/toc/1226-3303; https://doaj.org/toc/2005-6648
Dostęp URL:
https://doaj.org/article/e125d86b02dc4c33baa8a1e63e2a48ab  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.
Autorzy:
Soliai MM; Departments of Human Genetics, University of Chicago, Chicago, IL, USA. .; Committee on Genetics, Genomics and Systems Biology, University of Chicago, Chicago, IL, USA. .
Kato A; Departments of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Helling BA; Departments of Human Genetics, University of Chicago, Chicago, IL, USA.
Stanhope CT; Departments of Human Genetics, University of Chicago, Chicago, IL, USA.
Norton JE; Departments of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Naughton KA; Departments of Human Genetics, University of Chicago, Chicago, IL, USA.
Klinger AI; Departments of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Thompson EE; Departments of Human Genetics, University of Chicago, Chicago, IL, USA.
Clay SM; Departments of Human Genetics, University of Chicago, Chicago, IL, USA.
Kim S; Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, USA.
Celedón JC; Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, USA.
Gern JE; Department of Pediatrics, University of Wisconsin, School of Medicine and Public Health, Madison, WI, 53706, USA.
Jackson DJ; Department of Pediatrics, University of Wisconsin, School of Medicine and Public Health, Madison, WI, 53706, USA.
Altman MC; Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA.; Systems Immunology Program, Benaroya Research Institute, Seattle, WA, USA.
Kern RC; Department of Otolaryngology-Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Tan BK; Department of Otolaryngology-Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Schleimer RP; Departments of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Nicolae DL; Department of Statistics, University of Chicago, Chicago, IL, USA.
Pinto JM; Department of Surgery, University of Chicago, Chicago, IL, USA.
Ober C; Departments of Human Genetics, University of Chicago, Chicago, IL, USA. .; Committee on Genetics, Genomics and Systems Biology, University of Chicago, Chicago, IL, USA. .
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Źródło:
Genome medicine [Genome Med] 2021 Oct 10; Vol. 13 (1), pp. 157. Date of Electronic Publication: 2021 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Genome-Wide Association Study*
Asthma/*genetics
Genetic Predisposition to Disease/*genetics
Adolescent ; Adult ; Aged ; Asthma/virology ; Bayes Theorem ; DNA Methylation ; Epithelial Cells ; Female ; Gene Expression ; Genes, erbB-2 ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci ; Rhinovirus ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
HER2 testing by immunohistochemistry in breast cancer: A multicenter proficiency ring study.
Autorzy:
Md Pauzi SH; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Masir N; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Yahaya A; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Mohammed F; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Tizen Laim NMS; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Mustangin M; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Aizudin AN; Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Talib A; Department of Pathology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
Teoh KH; Department of Pathology, University Malaya Medical Centre, Lembah Pantai, Kuala Lumpur, Kuala Lumpur.
Karim N; Department of Pathology, Hospital Raja Permaisuri Bainun, 30450 Ipoh, Perak, Malaysia.
Oy-Leng JW; Department of Pathology, Sarawak General Hospital, 93586 Kuching, Sarawak, Malaysia.
Rajadurai P; Subang Jaya Medical Centre, 47500 Subang Jaya, Selangor, Malaysia.
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Źródło:
Indian journal of pathology & microbiology [Indian J Pathol Microbiol] 2021 Oct-Dec; Vol. 64 (4), pp. 677-682.
Typ publikacji:
Comparative Study; Journal Article; Multicenter Study
MeSH Terms:
Genes, erbB-2*
Breast Neoplasms/*genetics
Breast Neoplasms/*metabolism
Carcinoma/*genetics
Carcinoma/*metabolism
Immunohistochemistry/*statistics & numerical data
Receptor, ErbB-2/*metabolism
Adult ; Aged ; Aged, 80 and over ; Female ; Genetic Variation ; Humans ; Immunohistochemistry/methods ; Middle Aged ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Quantitative assessment of HER2 gene amplification of breast cancer using droplet digital PCR.
Autorzy:
Otsuji K; Department of Breast and Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.; NEXT-Ganken Program, The Cancer Institute of Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan.
Sasaki T; Department of Next-Generation Pathology Information and Networking, Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Tanabe M; Department of Breast and Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Seto Y; Department of Breast and Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.; Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
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Źródło:
Pathology international [Pathol Int] 2021 Aug; Vol. 71 (8), pp. 538-547. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/diagnosis
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Breast Neoplasms*/pathology
Oncogene Proteins v-erbB/*genetics
Polymerase Chain Reaction/*methods
Adult ; Aged ; Aged, 80 and over ; Female ; Genes, erbB-2 ; Humans ; In Situ Hybridization, Fluorescence ; Middle Aged ; Paraffin Embedding ; Pathology, Molecular
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multigene PCR using both cfDNA and cfRNA in the supernatant of pleural effusion achieves accurate and rapid detection of mutations and fusions of driver genes in patients with advanced NSCLC.
Autorzy:
Chen X; Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China.
Li K; Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China.
Liu Z; Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China.
Gai F; Medical Department, Amoy Diagnostics Co., Ltd., Xiamen, China.
Zhu G; Medical Department, Amoy Diagnostics Co., Ltd., Xiamen, China.
Lu S; Department of Oncology, Shanghai Chest Hospital Shanghai Jiaotong University, Shanghai, China.
Che N; Department of Pathology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis And Thoracic Tumor Research Institute, Beijing, China.
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Źródło:
Cancer medicine [Cancer Med] 2021 Apr; Vol. 10 (7), pp. 2286-2292. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Fusion*
Mutation*
Carcinoma, Non-Small-Cell Lung/*genetics
Cell-Free Nucleic Acids/*genetics
Lung Neoplasms/*genetics
Pleural Effusion, Malignant/*genetics
Anaplastic Lymphoma Kinase/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; DNA, Neoplasm ; Female ; Genes, erbB-1 ; Genes, erbB-2 ; Genes, ras ; Humans ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Pleural Effusion, Malignant/pathology ; Polymerase Chain Reaction/methods ; Sensitivity and Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Antimetastatic and Antitumor Activities of Orally Administered NAX014 Compound in a Murine Model of HER2-Positive Breast Cancer.
Autorzy:
Pierpaoli E; Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.
Piacenza F; Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.
Fiorillo G; Naxospharma Srl, 20026 Novate Milanese, Italy.
Lombardi P; Naxospharma Srl, 20026 Novate Milanese, Italy.
Orlando F; Experimental Animal Models for Aging Unit, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.
Salvatore C; Aesis Therapeutics Srl, Incubatore JCube, 60035 Jesi, Italy.
Geroni C; Aesis Therapeutics Srl, Incubatore JCube, 60035 Jesi, Italy.
Provinciali M; Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.; Experimental Animal Models for Aging Unit, Scientific Technological Area, IRCCS INRCA, 60121 Ancona, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 06; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, erbB-2*
Antineoplastic Agents/*therapeutic use
Berberine Alkaloids/*therapeutic use
Mammary Neoplasms, Experimental/*prevention & control
Neoplasm Metastasis/*prevention & control
Administration, Oral ; Animals ; Antineoplastic Agents/administration & dosage ; Berberine Alkaloids/administration & dosage ; Berberine Alkaloids/chemistry ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Drug Screening Assays, Antitumor ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Mammary Neoplasms, Experimental/drug therapy ; Mammary Neoplasms, Experimental/genetics ; Mice ; Mice, Transgenic ; Molecular Structure ; Neoplasm Metastasis/drug therapy ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/genetics ; Rats ; Tumor Burden/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.
Autorzy:
Nachmanson D; Bioinformatics and Systems Biology Graduate Program - UC San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Steward J; Moores Cancer Center - UC San Diego Health - 3855 Health Sciences Dr., La Jolla, CA, 92093, USA.
Yao H; Institute for Genomic Medicine - UC San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Officer A; Bioinformatics and Systems Biology Graduate Program - UC San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, USA.; Division of Biomedical Informatics, Department of Medicine - UC San Diego School of Medicine, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Jeong E; Moores Cancer Center - UC San Diego Health - 3855 Health Sciences Dr., La Jolla, CA, 92093, USA.
O'Keefe TJ; Division of Breast Surgery and The Comprehensive Breast Health Center - UC San Diego School of Medicine, 3855 Health Sciences Dr., La Jolla, CA, 92093, USA.
Hasteh F; Department of Pathology - UC San Diego School of Medicine, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Jepsen K; Institute for Genomic Medicine - UC San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, USA.
Hirst GL; Helen Diller Family Comprehensive Cancer Center - UC San Francisco School of Medicine, 1450 3rd St, San Francisco, CA, 94158, USA.
Esserman LJ; Helen Diller Family Comprehensive Cancer Center - UC San Francisco School of Medicine, 1450 3rd St, San Francisco, CA, 94158, USA.
Borowsky AD; Department of Pathology and Laboratory Medicine - UC Davis Comprehensive Cancer Center, UC Davis School of Medicine, 2279 45th Street, Sacramento, CA, 95817, USA.
Harismendy O; Moores Cancer Center - UC San Diego Health - 3855 Health Sciences Dr., La Jolla, CA, 92093, USA. .; Division of Biomedical Informatics, Department of Medicine - UC San Diego School of Medicine, 9500 Gilman Dr., La Jolla, CA, 92093, USA. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2020 Nov 18; Vol. 13 (1), pp. 173. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Specimen Banks*
Specimen Handling*
Breast Neoplasms/*genetics
Carcinoma, Intraductal, Noninfiltrating/*genetics
DNA Mutational Analysis/*methods
Sequence Analysis, DNA/*methods
Benchmarking ; Clone Cells ; DNA Copy Number Variations ; DNA Fragmentation ; Dissection/methods ; Female ; Gene Library ; Genes, erbB-2 ; Genetic Heterogeneity ; Humans ; INDEL Mutation ; Mutation ; Paraffin Embedding ; Polymorphism, Single Nucleotide ; Real-Time Polymerase Chain Reaction ; Tissue Fixation
Czasopismo naukowe
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