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Tytuł :
CDKN2A deletions are associated with poor outcomes in 101 adults with T-cell acute lymphoblastic leukemia.
Autorzy :
Wang HP; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Zhou YL; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Huang X; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Zhang Y; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Qian JJ; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Li JH; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Li XY; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Li CY; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Lou YJ; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Mai WY; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Meng HT; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Yu WJ; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Tong HY; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Jin J; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Zhu HH; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
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Źródło :
American journal of hematology [Am J Hematol] 2021 Mar 01; Vol. 96 (3), pp. 312-319. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Deletion*
Genes, p16*
Cyclin-Dependent Kinase Inhibitor p16/*deficiency
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Adolescent ; Adult ; Aged ; Allografts ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; China/epidemiology ; Combined Modality Therapy ; DNA Mutational Analysis ; DNA, Neoplasm/genetics ; Female ; Hematopoietic Stem Cell Transplantation ; High-Throughput Nucleotide Sequencing ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/mortality ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/therapy ; Prognosis ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
p16 methylation is a potential predictive marker for abemaciclib sensitivity in gastric cancer.
Autorzy :
Bae HJ; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kang SK; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kwon WS; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jeong I; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.
Park S; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Biostatistics and Computing, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim TS; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim KH; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim H; Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jeong HC; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
Chung HC; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
Rha SY; Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2021 Jan; Vol. 183, pp. 114320. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aminopyridines/*pharmacology
Benzimidazoles/*pharmacology
DNA Methylation/*drug effects
Drug Resistance, Neoplasm/*drug effects
Genes, p16/*drug effects
Stomach Neoplasms/*metabolism
Aminopyridines/therapeutic use ; Animals ; Benzimidazoles/therapeutic use ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; DNA Methylation/physiology ; Dose-Response Relationship, Drug ; Drug Resistance, Neoplasm/physiology ; Female ; Genes, p16/physiology ; Humans ; Mice ; Mice, Nude ; Predictive Value of Tests ; Stomach Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
Clinical Effect of Driver Mutations of KRAS, CDKN2A/P16, TP53 , and SMAD4 in Pancreatic Cancer: A Meta-Analysis.
Autorzy :
Gu Y; Department of Ultrasound Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou City, China.
Ji Y; Department of Interventional Ultrasound, Xianyang Central Hospital, Xianyang City, China.
Jiang H; Medical Imaging Department, Zhaoqing Medical College, Zhaoqing City, China.
Qiu G; Medical Imaging Department, Zhaoqing Medical College, Zhaoqing City, China.
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Źródło :
Genetic testing and molecular biomarkers [Genet Test Mol Biomarkers] 2020 Dec; Vol. 24 (12), pp. 777-788.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Genes, p16*
Genes, p53*
Genes, ras*
Carcinoma, Pancreatic Ductal/*genetics
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Pancreatic Neoplasms/*genetics
Proto-Oncogene Proteins p21(ras)/*genetics
Smad4 Protein/*genetics
Tumor Suppressor Protein p53/*genetics
Age Factors ; Aged ; Biomarkers, Tumor/genetics ; Carcinoma, Pancreatic Ductal/mortality ; Carcinoma, Pancreatic Ductal/pathology ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness/genetics ; Neoplasm Metastasis ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/pathology ; Prognosis ; Sex Factors
Czasopismo naukowe
Tytuł :
Dual disruption of eNOS and ApoE gene accelerates kidney fibrosis and senescence after injury.
Autorzy :
Nishimura K; Department of Nephrology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, 7708503, Japan.
Taguchi K; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Kishi S; Department of Nephrology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, 7708503, Japan; Department of General Medicine, Kawasaki Medical School, Kurashiki, 7010192, Japan. Electronic address: .
Brooks CR; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. Electronic address: .
Ochi A; Department of Nephrology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, 7708503, Japan.
Kadoya H; Department of Nephrology and Hypertension, Kawasaki Medical School, Kurashiki, 7010192, Japan.
Ikeda Y; Department of Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, 7708503, Japan.
Miyoshi M; Department of Medical Technology, Tokushima University Hospital, Tokushima, 7708503, Japan.
Tamaki M; Department of Nephrology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, 7708503, Japan.
Abe H; Department of Nephrology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, 7708503, Japan.
Aihara KI; Department of Community Medicine for Diabetes and Metabolic Disorders, Tokushima University Graduate School of Biomedical Sciences, Tokushima, 7708503, Japan.
Kashihara N; Department of Nephrology and Hypertension, Kawasaki Medical School, Kurashiki, 7010192, Japan.
Nagai K; Department of Nephrology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, 7708503, Japan.
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jun 04; Vol. 556, pp. 142-148. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Deletion*
Apolipoproteins E/*deficiency
Cellular Senescence/*genetics
Fibrosis/*genetics
Kidney/*pathology
Nitric Oxide Synthase Type III/*deficiency
Renal Insufficiency, Chronic/*genetics
Animals ; Apolipoproteins E/genetics ; Autophagy ; Blood Pressure ; Cyclin-Dependent Kinase Inhibitor p21 ; DNA Damage/genetics ; Genes, p16 ; Genes, p53 ; Humans ; Kidney/injuries ; Lipids ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nitric Oxide Synthase Type III/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Prognostic value of a 15-gene hypoxia classifier in oropharyngeal cancer treated with accelerated chemoradiotherapy.
Autorzy :
Deschuymer S; Department of Radiation Oncology, University Hospitals Leuven, KU Leuven - University of Leuven, Herestraat 49, 3000, Leuven, Belgium.
Sørensen BS; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.
Dok R; Laboratory of Experimental Radiotherapy, Department of Oncology, KU Leuven - University of Leuven, Leuven, Belgium.
Laenen A; Leuven Biostatistics and Statistical Bioinformatics Center, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.
Hauben E; Department of Imaging and Pathology, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.
Overgaard J; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.
Nuyts S; Department of Radiation Oncology, University Hospitals Leuven, KU Leuven - University of Leuven, Herestraat 49, 3000, Leuven, Belgium. .; Laboratory of Experimental Radiotherapy, Department of Oncology, KU Leuven - University of Leuven, Leuven, Belgium. .
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Źródło :
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] [Strahlenther Onkol] 2020 Jun; Vol. 196 (6), pp. 552-560. Date of Electronic Publication: 2020 Feb 20.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Chemoradiotherapy*/methods
Diffusion Magnetic Resonance Imaging*
Genes, p16*
Carcinoma, Squamous Cell/*therapy
Cell Hypoxia/*genetics
Oropharyngeal Neoplasms/*therapy
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents, Alkylating/therapeutic use ; Antineoplastic Agents, Immunological/therapeutic use ; Carcinoma, Squamous Cell/chemistry ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/mortality ; Cetuximab/therapeutic use ; Cisplatin/therapeutic use ; Female ; Follow-Up Studies ; Gene Expression Profiling ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Oropharyngeal Neoplasms/chemistry ; Oropharyngeal Neoplasms/genetics ; Oropharyngeal Neoplasms/mortality ; Oxygen/analysis ; Prognosis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Selected CDKN2A and MDM2 polymorphisms in oral cavity cancer.
Autorzy :
Gaździcka J; Medical University of Silesia. .
Gołąbek K; Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.
Strzelczyk JK; Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.
Kiczmer P; Department of Pathomorphology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.
Miśkiewicz-Orczyk K; Department of Otorhinolaryngology and Oncological Laryngology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Zabrze, Poland.
Krakowczyk Ł; Clinic of Oncological and Reconstructive Surgery, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland.
Ostrowska Z; Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.
Misiołek M; Department of Otorhinolaryngology and Oncological Laryngology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Zabrze, Poland.
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Źródło :
Acta biochimica Polonica [Acta Biochim Pol] 2020 May 07; Vol. 67 (2), pp. 213-218.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, p16*
Polymorphism, Single Nucleotide*
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Mouth Neoplasms/*genetics
Proto-Oncogene Proteins c-mdm2/*genetics
Squamous Cell Carcinoma of Head and Neck/*genetics
Adolescent ; Adult ; Aged ; Alleles ; Case-Control Studies ; Female ; Genotype ; Homozygote ; Humans ; Male ; Middle Aged ; Mouth Neoplasms/pathology ; Risk Factors ; Squamous Cell Carcinoma of Head and Neck/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Expression of p16 and HPV E4 on biopsy samples and methylation of FAM19A4 and miR124-2 on cervical cytology samples in the classification of cervical squamous intraepithelial lesions.
Autorzy :
Leeman A; DDL Diagnostic Laboratory, Rijswijk, The Netherlands.
Jenkins D; DDL Diagnostic Laboratory, Rijswijk, The Netherlands.
Del Pino M; Institute of Gynecology, Obstetrics and Neonatology, Hospital Clínic-Institut d´Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Faculty of Medicine-University of Barcelona, Barcelona, Spain.
Ordi J; Department of Pathology, ISGlobal, Hospital Clinic of Barcelona, Universitat de Barcelona, Barcelona, Spain.
Torné A; Institute of Gynecology, Obstetrics and Neonatology, Hospital Clínic-Institut d´Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Faculty of Medicine-University of Barcelona, Barcelona, Spain.
Doorbar J; Department of Pathology, University of Cambridge, Cambridge, United Kingdom.
Meijer CJLM; Amsterdam Medical Center, Department of Pathology, VU University Medical Centre, Amsterdam, The Netherlands.
van Kemenade FJ; Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Quint WGV; DDL Diagnostic Laboratory, Rijswijk, The Netherlands.
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Źródło :
Cancer medicine [Cancer Med] 2020 Apr; Vol. 9 (7), pp. 2454-2461. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Genes, p16*
Cervical Intraepithelial Neoplasia/*pathology
Cytokines/*metabolism
MicroRNAs/*genetics
Oncogene Proteins, Viral/*metabolism
Papillomavirus Infections/*complications
Uterine Cervical Neoplasms/*pathology
Adult ; Cervical Intraepithelial Neoplasia/metabolism ; Cervical Intraepithelial Neoplasia/surgery ; Cervical Intraepithelial Neoplasia/virology ; Cytokines/genetics ; Female ; Follow-Up Studies ; Humans ; Papillomaviridae/isolation & purification ; Papillomavirus Infections/virology ; Prognosis ; Uterine Cervical Neoplasms/metabolism ; Uterine Cervical Neoplasms/surgery ; Uterine Cervical Neoplasms/virology
Czasopismo naukowe
Tytuł :
Impact of delayed adjuvant therapy after surgery in p16 positive oropharyngeal cancer: a retrospective analysis.
Autorzy :
Sievert M; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Germany. .
Goncalves M
Mueller SK
Hecht M
Pflaum A
Grundtner P
Iro H
Gostian AO
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Źródło :
European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2020 Feb; Vol. 24 (3), pp. 1211-1218.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, p16*
Chemoradiotherapy/*methods
Oropharyngeal Neoplasms/*surgery
Papillomavirus Infections/*surgery
Time-to-Treatment/*trends
Aged ; Cohort Studies ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Oropharyngeal Neoplasms/mortality ; Oropharyngeal Neoplasms/therapy ; Papillomavirus Infections/mortality ; Papillomavirus Infections/therapy ; Retrospective Studies ; Survival Rate/trends
Czasopismo naukowe
Tytuł :
Efficacy and safety of an adsorbent and anti-oxidative vaginal gel on CIN1 and 2, on high-risk HPV, and on p16/Ki-67: a randomized controlled trial.
Autorzy :
Major AL; Femina Gynecology Center, Rue Emile-Yung 1, 1205, Geneva, Switzerland. .; Department of Obstetrics and Gynecology, Cantonal Hospital, University of Fribourg, Fribourg, Switzerland. .
Dvořák V; Centrum ambulantní Gynekologie a primární péče, s.r.o., Brno, Czech Republic.
Schwarzová J; Smetanova 388, 252 64 Velké Prilepy, Prague-West, Czech Republic.
Skřivánek A; G-CENTRUM Olomouc, s.r.o., Olomouc, Czech Republic.
Malík T; Gyneko spol. s.r.o., Vsetin, Czech Republic.
Pluta M; Fakultní Nemocnice v Motole (University Hospital Motol), Onkogynekologická a kolposkopická Ambulance, Praha, Czech Republic.
Mayboroda I; Department of Obstetrics and Gynecology, University Hospital of Geneva, Geneva, Switzerland.
Grandjean EM; Phidalsa Pharma-Consultants, Petit-Lancy/Geneva, Switzerland.; Camara-Partners, Consultant, Nyon, Switzerland.
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Źródło :
Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2021 Feb; Vol. 303 (2), pp. 501-511. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Vaginal Creams, Foams, and Jellies*
Cervical Intraepithelial Neoplasia/*therapy
Cyclin-Dependent Kinase Inhibitor p16/*drug effects
Ki-67 Antigen/*drug effects
Papillomavirus Infections/*therapy
Silicon Dioxide/*administration & dosage
Sodium Selenite/*administration & dosage
Administration, Intravaginal ; Adult ; Antioxidants/administration & dosage ; Biomarkers, Tumor/analysis ; Cervical Intraepithelial Neoplasia/pathology ; Citric Acid/administration & dosage ; Colposcopy ; Cytodiagnosis ; Female ; Genes, p16 ; Humans ; Middle Aged ; Papillomavirus Infections/virology ; Pregnancy ; Treatment Outcome ; Uterine Cervical Neoplasms/prevention & control ; Vaginal Smears
Czasopismo naukowe
Tytuł :
Clinical Significance of P16 Gene Methylation in Lung Cancer.
Autorzy :
Li Y; Center for Clinical Single Cell Biomedicine, Henan Provincial People's Hospital, Zhengzhou, Henan, China.; Zhengzhou University People's Hospital, Zhengzhou, Henan, China.; Henan University People's Hospital, Zhengzhou, Henan, China.
Zhang T; Center for Clinical Single Cell Biomedicine, Henan Provincial People's Hospital, Zhengzhou, Henan, China.; Zhengzhou University People's Hospital, Zhengzhou, Henan, China.; Henan University People's Hospital, Zhengzhou, Henan, China.
Zhang H; Center for Clinical Single Cell Biomedicine, Henan Provincial People's Hospital, Zhengzhou, Henan, China.; Zhengzhou University People's Hospital, Zhengzhou, Henan, China.; Henan University People's Hospital, Zhengzhou, Henan, China.
Wang X; Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China.
Liu X; Center for Clinical Single Cell Biomedicine, Henan Provincial People's Hospital, Zhengzhou, Henan, China.; Zhengzhou University People's Hospital, Zhengzhou, Henan, China.; Henan University People's Hospital, Zhengzhou, Henan, China.
Huang Q; Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China.
Li L; Center for Clinical Single Cell Biomedicine, Henan Provincial People's Hospital, Zhengzhou, Henan, China. .; Zhengzhou University People's Hospital, Zhengzhou, Henan, China. .; Henan University People's Hospital, Zhengzhou, Henan, China. .; Department of Scientific Research and Discipline Construction, Henan Provincial People's Hospital, Zhengzhou, Henan, China. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2020; Vol. 1255, pp. 133-142.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Methylation*
Genes, p16*
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Lung Neoplasms/*genetics
Humans ; Promoter Regions, Genetic
Czasopismo naukowe
Tytuł :
A panel of DNA methylated markers predicts metastasis of pN 0 M 0 gastric carcinoma: a prospective cohort study.
Autorzy :
Liu Z; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Etiology, Peking University Cancer Hospital and Institute, Fu-Cheng-Lu, No. 52, Haidian District, Beijing, 100142, China.
Cheng X; Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Fu-Cheng-Lu, No. 52, Haidian District, Beijing, 100142, China.
Zhang L; Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Fu-Cheng-Lu, No. 52, Haidian District, Beijing, 100142, China.
Zhou J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Etiology, Peking University Cancer Hospital and Institute, Fu-Cheng-Lu, No. 52, Haidian District, Beijing, 100142, China.
Deng D; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Etiology, Peking University Cancer Hospital and Institute, Fu-Cheng-Lu, No. 52, Haidian District, Beijing, 100142, China. .
Ji J; Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Fu-Cheng-Lu, No. 52, Haidian District, Beijing, 100142, China. .
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Źródło :
British journal of cancer [Br J Cancer] 2019 Oct; Vol. 121 (7), pp. 529-536. Date of Electronic Publication: 2019 Aug 21.
Typ publikacji :
Clinical Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation*
Genes, p16*
Antigens, CD/*genetics
Cadherins/*genetics
DNA-Binding Proteins/*genetics
Glial Cell Line-Derived Neurotrophic Factor Receptors/*genetics
Stomach Neoplasms/*genetics
Transcription Factors/*genetics
Biomarkers, Tumor/genetics ; Collagen Type II/genetics ; Confidence Intervals ; Double-Blind Method ; Feasibility Studies ; Female ; Genes, Neoplasm ; Genetic Markers ; Humans ; Male ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Odds Ratio ; Prospective Studies ; Risk ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Survival Analysis
Czasopismo naukowe
Tytuł :
p16 as an independent marker for detection of high-risk HPV in oral submucous fibrosis and oral squamous cell carcinoma.
Autorzy :
Sudhakaran A; Department of Oral and Maxillofacial Pathology, SDM College of Dental Sciences and Hospital, Dharwad, Bangalore, Karnataka, India.
Hallikeri K; Department of Oral and Maxillofacial Pathology, SDM College of Dental Sciences and Hospital, Dharwad, Bangalore, Karnataka, India.
Babu B; Department of Oral and Maxillofacial Pathology, SDM College of Dental Sciences and Hospital, Dharwad, Bangalore, Karnataka, India.
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Źródło :
Indian journal of pathology & microbiology [Indian J Pathol Microbiol] 2019 Oct-Dec; Vol. 62 (4), pp. 523-528.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, p16*
Biomarkers, Tumor/*genetics
Carcinoma, Squamous Cell/*genetics
Oral Submucous Fibrosis/*genetics
Adult ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/virology ; Female ; Humans ; Male ; Neoplasm Staging ; Oral Submucous Fibrosis/diagnosis ; Oral Submucous Fibrosis/virology ; Papillomaviridae/pathogenicity ; Papillomavirus Infections/complications ; Paraffin Embedding
Czasopismo naukowe
Tytuł :
Human papillomavirus and p16 immunostaining, prevalence and prognosis of squamous carcinoma of unknown primary in the head and neck region.
Autorzy :
Ren J; Department of Oto-Rhino-Laryngology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.; Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Yang W; Department of Oto-Rhino-Laryngology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
Su J; Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Ren X; Department of Economic Statistics, School of Statistics and Management, Shanghai University of Finance and Economics, Shanghai, China.
Fazelzad R; Library and Information Services, University Health Network, Toronto, ON, Canada.
Albert T; Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Habbous S; Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Goldstein DP; Department of Otolaryngology- Head and Neck Surgery, Princess Margaret Cancer Centre - University Health Network, University of Toronto, Toronto, ON, Canada.
de Almeida JR; Department of Otolaryngology- Head and Neck Surgery, Princess Margaret Cancer Centre - University Health Network, University of Toronto, Toronto, ON, Canada.
Hansen A; Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Jang R; Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Bratman SV; Department of Radiation Oncology, University of Toronto, and Princess Margaret Cancer Centre, Toronto, ON, Canada.
Hope A; Department of Radiation Oncology, University of Toronto, and Princess Margaret Cancer Centre, Toronto, ON, Canada.
Chen R; Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Wang J; Department of Oto-Rhino-Laryngology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
Xu Y; Department of Oto-Rhino-Laryngology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
Cheng D; Department of Oto-Rhino-Laryngology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
Zhao Y; Department of Oto-Rhino-Laryngology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
Xu W; Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Liu G; Medical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
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Źródło :
International journal of cancer [Int J Cancer] 2019 Sep 15; Vol. 145 (6), pp. 1465-1474. Date of Electronic Publication: 2019 Feb 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Genes, p16*
Alphapapillomavirus/*isolation & purification
Head and Neck Neoplasms/*pathology
Neoplasms, Unknown Primary/*pathology
Squamous Cell Carcinoma of Head and Neck/*pathology
Alphapapillomavirus/genetics ; Head and Neck Neoplasms/genetics ; Head and Neck Neoplasms/virology ; Humans ; Neoplasms, Unknown Primary/virology ; Prognosis ; Squamous Cell Carcinoma of Head and Neck/virology ; Survival Analysis
Czasopismo naukowe
Tytuł :
Targeting G1/S phase cell-cycle genomic alterations and accompanying co-alterations with individualized CDK4/6 inhibitor-based regimens.
Autorzy :
Kato S; Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, Moores Cancer Center at UC San Diego Health, La Jolla, California, USA.
Okamura R; Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, Moores Cancer Center at UC San Diego Health, La Jolla, California, USA.
Adashek JJ; Department of Internal Medicine, University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA.
Khalid N; Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, Moores Cancer Center at UC San Diego Health, La Jolla, California, USA.
Lee S; Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, Moores Cancer Center at UC San Diego Health, La Jolla, California, USA.
Nguyen V; Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, Moores Cancer Center at UC San Diego Health, La Jolla, California, USA.
Sicklick JK; Center for Personalized Cancer Therapy and Division of Surgical Oncology, Department of Surgery, Moores Cancer Center at UC San Diego Health, La Jolla, California, USA.
Kurzrock R; Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, Moores Cancer Center at UC San Diego Health, La Jolla, California, USA.
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Źródło :
JCI insight [JCI Insight] 2021 Jan 11; Vol. 6 (1). Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Cyclin-Dependent Kinase 4/*antagonists & inhibitors
Cyclin-Dependent Kinase 6/*antagonists & inhibitors
G1 Phase Cell Cycle Checkpoints/*drug effects
G1 Phase Cell Cycle Checkpoints/*genetics
Neoplasms/*drug therapy
Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Cyclin D/genetics ; Cyclin-Dependent Kinase 4/genetics ; Cyclin-Dependent Kinase 6/genetics ; Cyclin-Dependent Kinase Inhibitor p15/genetics ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; Female ; Genes, p16 ; Humans ; MAP Kinase Signaling System/genetics ; Male ; Middle Aged ; Neoplasms/pathology ; Phosphatidylinositol 3-Kinases/genetics ; Progression-Free Survival ; Protein Kinase Inhibitors/therapeutic use ; Young Adult
Czasopismo naukowe
Tytuł :
Comprehensive Review of Numerical Chromosomal Aberrations in Chromophobe Renal Cell Carcinoma Including Its Variant Morphologies.
Autorzy :
Alaghehbandan R; Department of Pathology, Faculty of Medicine, Royal Columbian Hospital, University of British Columbia, Vancouver, BC.
Trpkov K; Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada.
Tretiakova M; Department of Pathology, University of Washington, Seattle, WA.
Luis AS; Department of Pathology, Portuguese Institute of Oncology of Porto Francisco Gentil, Porto, Portugal.
Rogala JD; Department of Pathology, Charles University in Prague, Faculty of Medicine and University Hospital in Plzen, Plzen, Czech Republic.
Hes O; Department of Pathology, Charles University in Prague, Faculty of Medicine and University Hospital in Plzen, Plzen, Czech Republic.
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Źródło :
Advances in anatomic pathology [Adv Anat Pathol] 2021 Jan; Vol. 28 (1), pp. 8-20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Chromosome Aberrations*
Carcinoma, Renal Cell/*genetics
Kidney Neoplasms/*genetics
Biomarkers, Tumor ; Carcinoma, Renal Cell/pathology ; Genes, p16 ; Genes, p53 ; Humans ; Kidney Neoplasms/pathology ; PTEN Phosphohydrolase/genetics
Czasopismo naukowe
Tytuł :
Homozygous deletion of CDKN2A in malignant mesothelioma: Diagnostic utility, patient characteristics and survival in a UK mesothelioma centre.
Autorzy :
Marshall K; Pleural Medicine, North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Jackson S; Pleural Medicine, North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Jones J; Pleural Medicine, North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Holme J; Pleural Medicine, North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Lyons J; Pleural Medicine, North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Barrett E; Department of Medical Statistics, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Taylor P; Department of Medical Oncology, North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Bishop P; Department of Cellular Pathology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Hodgson C; Department of Cytogenetics, The Christie NHS Foundation Trust, Wilmslow Rd, Manchester M20 4BX, UK.
Green M; Department of Cytogenetics, The Christie NHS Foundation Trust, Wilmslow Rd, Manchester M20 4BX, UK.
Telford N; Department of Cytogenetics, The Christie NHS Foundation Trust, Wilmslow Rd, Manchester M20 4BX, UK.
Evison M; Pleural Medicine, North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK. Electronic address: .
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Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2020 Dec; Vol. 150, pp. 195-200. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article
MeSH Terms :
Lung Neoplasms*/diagnosis
Lung Neoplasms*/genetics
Mesothelioma*/diagnosis
Mesothelioma*/genetics
Mesothelioma, Malignant*
Cyclin-Dependent Kinase Inhibitor p16/genetics ; Female ; Genes, p16 ; Homozygote ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Retrospective Studies ; Sequence Deletion ; United Kingdom
Czasopismo naukowe
Tytuł :
Identification of Radioresponsive Genes in Esophageal Cancer from Longitudinal and Single Cell Exome Sequencing.
Autorzy :
Yang L; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Zhang X; Hangzhou Cancer Institute, Hangzhou Cancer Hospital, Hangzhou, China.
MacKay M; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, New York.
Foox J; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, New York.
Hou Q; Hangzhou Cancer Institute, Hangzhou Cancer Hospital, Hangzhou, China.
Zheng X; Hangzhou Cancer Institute, Hangzhou Cancer Hospital, Hangzhou, China.
Zhou R; Department of Pathology, Hangzhou Cancer Hospital, Hangzhou, China.
Huang M; Hangzhou Cancer Institute, Hangzhou Cancer Hospital, Hangzhou, China.
Jing Z; Hangzhou Cancer Institute, Hangzhou Cancer Hospital, Hangzhou, China; Department of Radiation Oncology, Hangzhou Cancer Hospital, Hangzhou, China.
Mason CE; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, New York; The Feil Family Brain and Mind Research Institute (BMRI), New York, New York.
Wu S; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China. Electronic address: .
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Źródło :
International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2020 Nov 15; Vol. 108 (4), pp. 1103-1114. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Esophageal Neoplasms/*genetics
Esophageal Squamous Cell Carcinoma/*genetics
Neoplasm Recurrence, Local/*genetics
Radiation Tolerance/*genetics
Whole Exome Sequencing/*methods
Adult ; Aged ; Alleles ; China ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/radiotherapy ; Esophageal Squamous Cell Carcinoma/mortality ; Esophageal Squamous Cell Carcinoma/radiotherapy ; Female ; Genes, p16 ; Genes, p53 ; Humans ; Kaplan-Meier Estimate ; Male ; Microfilament Proteins/genetics ; Microtubule-Associated Proteins/genetics ; Middle Aged ; Mutation ; NF-E2-Related Factor 2/genetics ; Protein-Serine-Threonine Kinases/genetics ; Receptor, Notch1/genetics ; Rho Guanine Nucleotide Exchange Factors/genetics ; Single-Cell Analysis/methods ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
Histone Deacetylation in the Promoter of p16 Is Involved in Fluoride-Induced Human Osteoblast Activation via the Inhibition of Sp1 Binding.
Autorzy :
Ming J; Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
Wu S; Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
You T; Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
Wang X; Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
Yu C; Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China.; Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, China.
Luo P; Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China.; Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, China.
Zhang A; Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China.; Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, China.
Pan X; Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang, 550025, Guizhou, China. .; Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, China. .
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2019 Apr; Vol. 188 (2), pp. 373-383. Date of Electronic Publication: 2018 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, p16*
Cell Proliferation/*drug effects
Histones/*metabolism
Osteoblasts/*drug effects
Sodium Fluoride/*toxicity
Sp1 Transcription Factor/*metabolism
Acetylation ; Adult ; Cell Proliferation/genetics ; Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Female ; Fluoride Poisoning/metabolism ; Fluoride Poisoning/pathology ; Gene Expression Regulation/drug effects ; Humans ; Male ; Osteoblasts/metabolism ; Primary Cell Culture ; Promoter Regions, Genetic/genetics ; Protein Binding ; Response Elements/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
Smoking and papillomavirus DNA in patients with p16-positive N3 oropharyngeal squamous cell carcinoma.
Autorzy :
Gorphe P; Department of Head and Neck Oncology, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
Chekkoury Idrissi Y; Department of Head and Neck Oncology, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
Tao Y; Department of Radiotherapy, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
Moya-Plana A; Department of Head and Neck Oncology, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
Casiraghi O; Department of Pathology, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
Janot F; Department of Head and Neck Oncology, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
Blanchard P; Department of Radiotherapy, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
Mirghani H; Department of Head and Neck Oncology, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
Temam S; Department of Head and Neck Oncology, Gustave Roussy Institute, Université Paris-Saclay, Villejuif, France.
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Źródło :
Head & neck [Head Neck] 2019 Apr; Vol. 41 (4), pp. 1039-1045. Date of Electronic Publication: 2018 Dec 15.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, p16*
Head and Neck Neoplasms/*virology
Oropharyngeal Neoplasms/*virology
Papillomaviridae/*genetics
Smoking/*adverse effects
Squamous Cell Carcinoma of Head and Neck/*virology
Cohort Studies ; DNA, Viral/analysis ; Databases, Factual ; Disease-Free Survival ; Female ; Head and Neck Neoplasms/mortality ; Head and Neck Neoplasms/pathology ; Head and Neck Neoplasms/surgery ; Humans ; Kaplan-Meier Estimate ; Male ; Neoplasm Invasiveness/pathology ; Neoplasm Staging ; Oropharyngeal Neoplasms/mortality ; Oropharyngeal Neoplasms/pathology ; Oropharyngeal Neoplasms/surgery ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Risk Assessment ; Smoking/epidemiology ; Squamous Cell Carcinoma of Head and Neck/mortality ; Squamous Cell Carcinoma of Head and Neck/pathology ; Squamous Cell Carcinoma of Head and Neck/surgery ; Survival Analysis
Czasopismo naukowe
Tytuł :
HPV as a marker for molecular characterization in head and neck oncology: Looking for a standardization of clinical use and of detection method(s) in clinical practice.
Autorzy :
Bussu F; Institute of Otolaryngology, Università Cattolica del Sacro Cuore, Policlinico Agostino Gemelli, Rome, Italy.; Otolaryngology Division, Sassari University Hospital, Italy.
Ragin C; Cancer Prevention and Control Program, Fox Chase Cancer, Pennsylvania.
Boscolo-Rizzo P; Department of Neurosciences, ENT Clinic and Regional Center for Head and Neck Cancer, University of Padua, Treviso Regional Hospital, Treviso, Italy.
Rizzo D; Otolaryngology Division, Sassari University Hospital, Italy.
Gallus R; Institute of Otolaryngology, Università Cattolica del Sacro Cuore, Policlinico Agostino Gemelli, Rome, Italy.
Delogu G; Institute of Microbiology, Università Cattolica del Sacro Cuore, Policlinico Agostino Gemelli, Rome, Italy.
Morbini P; Department of Molecular Medicine, University of Pavia, Policlinico San Matteo, Pavia, Italy.
Tommasino M; Infections and Cancer Biology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.
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Źródło :
Head & neck [Head Neck] 2019 Apr; Vol. 41 (4), pp. 1104-1111. Date of Electronic Publication: 2019 Feb 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genes, p16*
Biomarkers, Tumor/*analysis
Carcinoma, Squamous Cell/*pathology
Oropharyngeal Neoplasms/*virology
Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/epidemiology ; Carcinoma, Squamous Cell/genetics ; Female ; Head and Neck Neoplasms/genetics ; Head and Neck Neoplasms/pathology ; Head and Neck Neoplasms/virology ; Humans ; In Situ Hybridization ; Male ; Neoplasm Invasiveness/pathology ; Neoplasm Staging ; Oropharyngeal Neoplasms/diagnosis ; Oropharyngeal Neoplasms/epidemiology ; Oropharyngeal Neoplasms/genetics ; Papillomaviridae/genetics ; Papillomavirus Infections/complications ; Papillomavirus Infections/diagnosis ; RNA, Messenger/genetics ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction/methods ; Risk Assessment
Czasopismo naukowe

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