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Wyszukujesz frazę ""Genes, p16"" wg kryterium: Temat


Wyświetlanie 1-12 z 12
Tytuł:
Comparative study of Rb1, cyclin D1 and p16 immunohistochemistry expression to distinguish lung small-cell carcinoma and large-cell neuroendocrine carcinoma.
Autorzy:
Papaxoinis G; Medical Oncology, Agios Savvas Anticancer Hospital, Athina, Greece.
Bille A; Department of Thoracic Surgery, Guy's and St Thomas' NHS Foundation Trust, London, UK.; King's College London, London, UK.
McLean E; Department of Cellular Pathology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Nonaka D; King's College London, London, UK.; Department of Cellular Pathology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
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Źródło:
Histopathology [Histopathology] 2022 Aug; Vol. 81 (2), pp. 205-214. Date of Electronic Publication: 2022 May 27.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Carcinoma, Large Cell*/pathology
Carcinoma, Neuroendocrine*/diagnosis
Carcinoma, Neuroendocrine*/pathology
Carcinoma, Small Cell*/diagnosis
Carcinoma, Small Cell*/pathology
Lung Neoplasms*/pathology
Small Cell Lung Carcinoma*/diagnosis
Small Cell Lung Carcinoma*/pathology
Cyclin D1/metabolism ; Genes, p16 ; Humans ; Immunohistochemistry ; Lung/pathology ; Retinoblastoma Binding Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł:
The prognostic value of epigenetic silencing of p16 gene in NSCLC patients: a systematic review and meta-analysis.
Autorzy:
Lou-Qian Z; Department of Thoracic Surgery, Jiangsu Cancer Hospital, Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Rong Y
Ming L
Xin Y
Feng J
Lin X
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Źródło:
PloS one [PLoS One] 2013; Vol. 8 (1), pp. e54970. Date of Electronic Publication: 2013 Jan 25.
Typ publikacji:
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms:
Epigenesis, Genetic*
Gene Silencing*
Genes, p16*
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/pathology ; DNA Methylation ; Humans ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Neoplasm Staging ; Odds Ratio ; Prognosis ; Promoter Regions, Genetic ; Publication Bias
Czasopismo naukowe
Tytuł:
Chromosome 9 instability and alterations of p16 gene in squamous cell carcinoma of the lung and in adjacent normal bronchi: FISH and immunohistochemical study.
Autorzy:
Dessy E; Second Department of Pathologic Anatomy, School of Medicine, University of Brescia, Brescia, Italy. />Rossi E
Berenzi A
Tironi A
Benetti A
Grigolato P
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Źródło:
Histopathology [Histopathology] 2008 Mar; Vol. 52 (4), pp. 475-82.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromosomal Instability*
Chromosomes, Human, Pair 9*
Genes, p16*
Genetic Predisposition to Disease*
Carcinoma, Squamous Cell/*genetics
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Lung Neoplasms/*genetics
Aged ; Aged, 80 and over ; Bronchi/anatomy & histology ; Bronchi/metabolism ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; Cell Nucleus/metabolism ; Cell Nucleus/pathology ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Female ; Humans ; Immunoenzyme Techniques ; In Situ Hybridization, Fluorescence ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Male ; Middle Aged
Czasopismo naukowe
Tytuł:
The relationship between aberrant methylation and survival in non-small-cell lung cancers.
Autorzy:
Toyooka S; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Suzuki M
Maruyama R
Toyooka KO
Tsukuda K
Fukuyama Y
Iizasa T
Aoe M
Date H
Fujisawa T
Shimizu N
Gazdar AF
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Źródło:
British journal of cancer [Br J Cancer] 2004 Aug 16; Vol. 91 (4), pp. 771-4.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
DNA Methylation*
Genes, p16*
Adenocarcinoma/*genetics
Adenocarcinoma/*pathology
Carcinoma, Non-Small-Cell Lung/*genetics
Carcinoma, Non-Small-Cell Lung/*pathology
DNA, Neoplasm/*metabolism
Lung Neoplasms/*genetics
Lung Neoplasms/*pathology
Aged ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Survival Analysis
Czasopismo naukowe
Tytuł:
Inactivation of the p16 gene by hypermethylation and loss of heterozygosity in adenocarcinoma of the lung.
Autorzy:
Awaya H; Department of Pathology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Takeshima Y
Amatya VJ
Furonaka O
Tagawa K
Kohno N
Inai K
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Źródło:
Pathology international [Pathol Int] 2004 Jul; Vol. 54 (7), pp. 486-9.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Methylation*
Gene Silencing*
Genes, p16*
Loss of Heterozygosity*
Adenocarcinoma/*genetics
Lung Neoplasms/*genetics
Adenocarcinoma/pathology ; Adult ; Aged ; Aged, 80 and over ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; DNA, Neoplasm/analysis ; Humans ; Immunohistochemistry ; Lung Neoplasms/pathology ; Microsatellite Repeats ; Middle Aged ; Polymerase Chain Reaction
Czasopismo naukowe
Tytuł:
RB and cyclin dependent kinase pathways: defining a distinction between RB and p16 loss in lung cancer.
Autorzy:
Kaye FJ; Genetics Branch, Center for Cancer Research, NCI, NIH and National Naval Medical Center, Bethesda, Maryland 20889, USA.
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Źródło:
Oncogene [Oncogene] 2002 Oct 07; Vol. 21 (45), pp. 6908-14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Gene Deletion*
Genes, Retinoblastoma*
Genes, p16*
Proto-Oncogene Proteins*
Carcinoma, Small Cell/*genetics
Cyclin-Dependent Kinases/*genetics
Lung Neoplasms/*genetics
Cyclin-Dependent Kinase 4 ; Cyclin-Dependent Kinases/metabolism ; Humans
Czasopismo naukowe
Tytuł:
Homozygous deletions of methylthioadenosine phosphorylase (MTAP) are more frequent than p16INK4A (CDKN2) homozygous deletions in primary non-small cell lung cancers (NSCLC).
Autorzy:
Schmid M; Stein Institute for Research on Aging, University of California, San Diego, La Jolla 92093, USA.
Malicki D
Nobori T
Rosenbach MD
Campbell K
Carson DA
Carrera CJ
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Źródło:
Oncogene [Oncogene] 1998 Nov 19; Vol. 17 (20), pp. 2669-75.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Gene Deletion*
Genes, Tumor Suppressor*
Genes, p16*
Carcinoma, Non-Small-Cell Lung/*genetics
Chromosomes, Human, Pair 9/*genetics
DNA, Neoplasm/*genetics
Lung Neoplasms/*genetics
Neoplasm Proteins/*genetics
Purine-Nucleoside Phosphorylase/*genetics
DNA Primers ; Homozygote ; Humans ; Male ; Polymerase Chain Reaction ; Pseudogenes
Czasopismo naukowe
Tytuł:
Comprehensive genomic characterization of squamous cell lung cancers.
Corporate Authors:
Cancer Genome Atlas Research Network; Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.
Źródło:
Nature [Nature] 2012 Sep 27; Vol. 489 (7417), pp. 519-25. Date of Electronic Publication: 2012 Sep 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Carcinoma, Squamous Cell/*genetics
Genome, Human/*genetics
Lung Neoplasms/*genetics
Mutation/*genetics
Adenocarcinoma/drug therapy ; Adenocarcinoma/genetics ; Adenocarcinoma/metabolism ; Adenocarcinoma of Lung ; Carcinoma, Squamous Cell/drug therapy ; Carcinoma, Squamous Cell/metabolism ; DNA Mutational Analysis ; Gene Deletion ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Genes, p16 ; Genes, p53/genetics ; Genomics ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/metabolism ; Molecular Targeted Therapy ; Mutation Rate ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł:
LKB1, TP16, EGFR, and KRAS somatic mutations in lung adenocarcinomas from a Chiba Prefecture, Japan cohort.
Autorzy:
Suzuki Y; Celish FD, Inc., Chiba-Shi, Chiba, Japan.
Oonishi T
Kudo T
Doi H
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Źródło:
Drug discoveries & therapeutics [Drug Discov Ther] 2012 Feb; Vol. 6 (1), pp. 24-30.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma/*genetics
Asian People/*genetics
Lung Neoplasms/*genetics
AMP-Activated Protein Kinase Kinases ; Adenocarcinoma/pathology ; Aged ; Aged, 80 and over ; Amino Acid Sequence ; ErbB Receptors/genetics ; Exons ; Female ; Gene Deletion ; Genes, p16 ; Humans ; Japan ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Mutation ; Protein Serine-Threonine Kinases/genetics ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins p21(ras) ; ras Proteins/genetics
Czasopismo naukowe
Tytuł:
Molecular processes of chromosome 9p21 deletions in human cancers.
Autorzy:
Sasaki S; Biology Division, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
Kitagawa Y
Sekido Y
Minna JD
Kuwano H
Yokota J
Kohno T
Pokaż więcej
Źródło:
Oncogene [Oncogene] 2003 Jun 12; Vol. 22 (24), pp. 3792-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Acid Anhydride Hydrolases*
Chromosomes, Human, Pair 9*
Lung Neoplasms/*genetics
Neoplasms/*genetics
Base Sequence ; Chromosome Deletion ; DNA Damage ; Genes, p16 ; Humans ; Molecular Sequence Data ; Neoplasm Proteins/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
    Wyświetlanie 1-12 z 12

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