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Tytuł:
Assessment and clinicopathological correlation of p16 expression in cervical squamous cell carcinoma of Indian population: Diagnostic implications.
Autorzy:
Paul A; Department of Pathology, Murshidabad Medical College and Hospital (MSDMCH), Berhampore, West Bengal, India.
Dutta P; Department of Oncogene Regulation Unit, Chittaranjan National Cancer Institute (CNCI), Kolkata, West Bengal, India.
Basu K; Department of Pathology, KPC Medical College, Kolkata, West Bengal, India.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Oct 01; Vol. 19 (7), pp. 2012-2017. Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Squamous Cell*/diagnosis
Carcinoma, Squamous Cell*/genetics
Genes, p16*
Uterine Cervical Neoplasms*/diagnosis
Uterine Cervical Neoplasms*/genetics
Female ; Humans ; Asian People ; Epithelium ; Papillomavirus E7 Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Construction and validation of a prognostic model for colon adenocarcinoma based on bile acid metabolism-related genes.
Autorzy:
Luo Q; Department of Anorectal Surgery, Wuyi Hospital of Traditional Chinese Medicine, Jiangmen, China. .
Zhou P; Department of Anorectal Surgery, Jiangxi Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, China.
Chang S; Department of Anorectal Surgery, Wuyi Hospital of Traditional Chinese Medicine, Jiangmen, China.
Huang Z; Department of Anorectal Surgery, Wuyi Hospital of Traditional Chinese Medicine, Jiangmen, China.
Zeng X; Department of Brain Diseases, Shenzhen Pingle Orthopaedic Hospital, Shenzhen, China.
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 05; Vol. 13 (1), pp. 12728. Date of Electronic Publication: 2023 Aug 05.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma*/genetics
Colonic Neoplasms*/genetics
Amino Acid Transport Systems, Neutral*
Humans ; Prognosis ; Genes, p16 ; Cyclin-Dependent Kinase Inhibitor Proteins ; Bile Acids and Salts ; Tumor Microenvironment/genetics ; Nerve Tissue Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Data mining on identifying diagnosis and prognosis biomarkers in head and neck squamous carcinoma.
Autorzy:
Ju G; The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, 210029, China.
Yao Z; Department of Head and Neck Surgery, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, 210029, China.
Zhao Y; Department of Head and Neck Surgery, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, 210029, China.
Zhao X; Department of Otorhinolaryngology and Head and Neck Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, Jiangsu, China. .
Liu F; Department of Head and Neck Surgery, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, 210029, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 20; Vol. 13 (1), pp. 10020. Date of Electronic Publication: 2023 Jun 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Squamous Cell*
Head and Neck Neoplasms*/diagnosis
Head and Neck Neoplasms*/genetics
Humans ; Genes, p16 ; Genes, Regulator ; Data Mining ; Cyclin-Dependent Kinase Inhibitor Proteins ; Prognosis ; Biomarkers, Tumor/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of germline cancer predisposition variants in pediatric sarcoma patients from somatic tumor testing.
Autorzy:
Alba-Pavón P; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Alaña L; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Gutierrez-Jimeno M; Department of Pediatrics, Clinica Universidad de Navarra, Pamplona, Spain.
García-Obregón S; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Department of Physiology, Faculty of Medicine and Nursing, University of the Basque Country, UPV/EHU, Leioa, Spain.
Imízcoz T; CIMA LAB Diagnostics, University of Navarra, Pamplona, Spain.
Panizo E; Department of Pediatrics, Clinica Universidad de Navarra, Pamplona, Spain.
González-Urdiales P; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Pediatrics Department, Hospital Universitario de Cruces, Osakidetza, Barakaldo, Spain.
Echebarria-Barona A; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Pediatrics Department, Hospital Universitario de Cruces, Osakidetza, Barakaldo, Spain.
Lopez Almaraz R; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Pediatrics Department, Hospital Universitario de Cruces, Osakidetza, Barakaldo, Spain.
Zaldumbide L; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Department of Pathology, Hospital Universitario de Cruces, Osakidetza, Barakaldo, Spain.
Astigarraga I; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Pediatrics Department, Hospital Universitario de Cruces, Osakidetza, Barakaldo, Spain.; Pediatrics Department, Faculty of Medicine and Nursing, University of the Basque Country, UPV/EHU, Leioa, Spain.
Patiño-García A; Department of Pediatrics, Clinica Universidad de Navarra, Pamplona, Spain.; CIMA LAB Diagnostics, University of Navarra, Pamplona, Spain.; Center for Applied Medical Research and IdiSNA, Solid Tumor Program, CIMA, Pamplona, Spain.
Villate O; Pediatric Oncology Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain. .
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Źródło:
Scientific reports [Sci Rep] 2023 Feb 20; Vol. 13 (1), pp. 2959. Date of Electronic Publication: 2023 Feb 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sarcoma*/diagnosis
Sarcoma*/genetics
Soft Tissue Neoplasms*
Adolescent ; Young Adult ; Humans ; Child ; Syndrome ; Genotype ; Genes, p16 ; Genetic Predisposition to Disease ; Cyclin-Dependent Kinase Inhibitor Proteins ; DNA Helicases ; Nuclear Proteins ; Transcription Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Feasibility of using P16 methylation as a cytologic marker for esophageal squamous cell carcinoma screening: A pilot study.
Autorzy:
Fan Z; Office of National Central Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qin Y; Office of National Central Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhou J; Key Laboratory of Carcinogenesis and Translational Research (MOE/Beijing), Division of Etiology, Peking University Cancer Hospital and Institute, Beijing, China.
Chen R; Office of National Central Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Gu J; Office of National Central Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li M; Office of National Central Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhou J; Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Li X; Office of National Central Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lin D; Department of Pathology, Peking University Cancer Hospital, Beijing, China.
Wang J; Department of Pathology, Linzhou Cancer Hospital, Linzhou, China.
Deng D; Key Laboratory of Carcinogenesis and Translational Research (MOE/Beijing), Division of Etiology, Peking University Cancer Hospital and Institute, Beijing, China.
Wei W; Office of National Central Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Źródło:
Cancer medicine [Cancer Med] 2022 Nov; Vol. 11 (21), pp. 4033-4042. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Esophageal Squamous Cell Carcinoma*/diagnosis
Esophageal Squamous Cell Carcinoma*/genetics
Esophageal Neoplasms*/diagnosis
Esophageal Neoplasms*/genetics
Esophageal Neoplasms*/metabolism
Carcinoma, Squamous Cell*/diagnosis
Carcinoma, Squamous Cell*/genetics
Carcinoma, Squamous Cell*/metabolism
Humans ; Genes, p16 ; Pilot Projects ; Feasibility Studies ; DNA Methylation ; Biomarkers/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative study of Rb1, cyclin D1 and p16 immunohistochemistry expression to distinguish lung small-cell carcinoma and large-cell neuroendocrine carcinoma.
Autorzy:
Papaxoinis G; Medical Oncology, Agios Savvas Anticancer Hospital, Athina, Greece.
Bille A; Department of Thoracic Surgery, Guy's and St Thomas' NHS Foundation Trust, London, UK.; King's College London, London, UK.
McLean E; Department of Cellular Pathology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Nonaka D; King's College London, London, UK.; Department of Cellular Pathology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
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Źródło:
Histopathology [Histopathology] 2022 Aug; Vol. 81 (2), pp. 205-214. Date of Electronic Publication: 2022 May 27.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Carcinoma, Large Cell*/pathology
Carcinoma, Neuroendocrine*/diagnosis
Carcinoma, Neuroendocrine*/pathology
Carcinoma, Small Cell*/diagnosis
Carcinoma, Small Cell*/pathology
Lung Neoplasms*/pathology
Small Cell Lung Carcinoma*/diagnosis
Small Cell Lung Carcinoma*/pathology
Cyclin D1/metabolism ; Genes, p16 ; Humans ; Immunohistochemistry ; Lung/pathology ; Retinoblastoma Binding Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Ferroptosis Molecular Subtype-Related Signature for Predicting Prognosis and Response to Chemotherapy in Patients with Chronic Lymphocytic Leukemia.
Autorzy:
Gong H; Department of Hematology, The Second Xiangya Hospital; Molecular Biology Research Center, Center for Medical Genetics, School of Life Sciences; Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha 410011, China.
Li H; Department of Hematology, The Second Xiangya Hospital; Molecular Biology Research Center, Center for Medical Genetics, School of Life Sciences; Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha 410011, China.
Yang Q; Department of Hematology, The Second Xiangya Hospital; Molecular Biology Research Center, Center for Medical Genetics, School of Life Sciences; Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha 410011, China.; School of Medical Laboratory, Shao Yang University, Hunan Province 422000, China.
Zhang G; Department of Dermatology, Hunan Key Laboratory of Skin Cancer and Psoriasis, Hunan Engineering Research Center of Skin Health and Disease, Xiangya Clinical Research Center for Cancer Immunotherapy, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Liu H; Department of Dermatology, Hunan Key Laboratory of Skin Cancer and Psoriasis, Hunan Engineering Research Center of Skin Health and Disease, Xiangya Clinical Research Center for Cancer Immunotherapy, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Ma Z; Department of Hematology, The Second Xiangya Hospital; Molecular Biology Research Center, Center for Medical Genetics, School of Life Sciences; Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha 410011, China.
Peng H; Department of Hematology, The Second Xiangya Hospital; Molecular Biology Research Center, Center for Medical Genetics, School of Life Sciences; Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha 410011, China.
Nie L; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Xiao X; Department of Hematology, The Second Xiangya Hospital; Molecular Biology Research Center, Center for Medical Genetics, School of Life Sciences; Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha 410011, China.
Liu J; Department of Hematology, The Second Xiangya Hospital; Molecular Biology Research Center, Center for Medical Genetics, School of Life Sciences; Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha 410011, China.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Jul 06; Vol. 2022, pp. 5646275. Date of Electronic Publication: 2022 Jul 06 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Ferroptosis*/genetics
Leukemia, Lymphocytic, Chronic, B-Cell*/diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell*/drug therapy
Leukemia, Lymphocytic, Chronic, B-Cell*/genetics
Cohort Studies ; Genes, p16 ; Humans ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Cdkn2a gene product p19 alternative reading frame (p19ARF) is a critical regulator of IFNβ-mediated Lyme arthritis.
Autorzy:
Li J; Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Ma Y; Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Paquette JK; Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Richards AC; Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Mulvey MA; Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Zachary JF; Department of Veterinary Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
Teuscher C; Department of Medicine, Vermont Center for Immunology and Infectious Diseases, Larner College of Medicine, The University of Vermont, Burlington, Vermont, United States of America.
Weis JJ; Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2022 Mar 24; Vol. 18 (3), pp. e1010365. Date of Electronic Publication: 2022 Mar 24 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Arthritis*/genetics
Cyclin-Dependent Kinase Inhibitor p16*/genetics
Lyme Disease*/genetics
Animals ; Borrelia burgdorferi ; Genes, p16 ; Interferon-beta/genetics ; Interferon-beta/metabolism ; Mice ; Mice, Inbred C3H ; Mice, Inbred C57BL ; RNA, Small Interfering ; Reading Frames ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Usefulness of circulating tumor DNA by targeting human papilloma virus-derived sequences as a biomarker in p16-positive oropharyngeal cancer.
Autorzy:
Akashi K; Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. .; Department of Otolaryngology and Head and Neck Surgery, Kameda Medical Center, Chiba, Japan. .
Sakai T; Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Fukuoka O; Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Saito Y; Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Yoshida M; Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.; Department of Otolaryngology, Showa General Hospital, Tokyo, Japan.
Ando M; Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.; Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Ito T; Division of Molecular Pathology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
Murakami Y; Division of Molecular Pathology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
Yamasoba T; Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 12; Vol. 12 (1), pp. 572. Date of Electronic Publication: 2022 Jan 12.
Typ publikacji:
Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Circulating Tumor DNA/*blood
Neoplasm Recurrence, Local/*blood
Oropharyngeal Neoplasms/*blood
Papillomaviridae/*genetics
Aged ; Aged, 80 and over ; Biomarkers, Tumor/blood ; Case-Control Studies ; Female ; Genes, p16 ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local/diagnostic imaging ; Neoplasm Recurrence, Local/therapy ; Neoplasm Recurrence, Local/virology ; Oropharyngeal Neoplasms/diagnostic imaging ; Oropharyngeal Neoplasms/therapy ; Oropharyngeal Neoplasms/virology ; Tomography, X-Ray Computed
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The novel AKT inhibitor afuresertib suppresses human Merkel cell carcinoma MKL-1 cell growth.
Autorzy:
Wu JH; Department of Dermatology, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.; Ronald O. Perelman Department of Dermatology, New York University, New York, NY, USA.
Limmer AL; Department of Dermatology, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
Narayanan D; Department of Dermatology, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
Doan HQ; Department of Dermatology, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.; Department of Dermatology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Simonette RA; Department of Dermatology, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
Rady PL; Department of Dermatology, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
Tyring SK; Department of Dermatology, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
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Źródło:
Clinical and experimental dermatology [Clin Exp Dermatol] 2021 Dec; Vol. 46 (8), pp. 1551-1554. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Carcinoma, Merkel Cell/*drug therapy
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Pyrazoles/*therapeutic use
Skin Neoplasms/*drug therapy
Thiophenes/*therapeutic use
Trans-Activators/*antagonists & inhibitors
Carcinoma, Merkel Cell/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Genes, p16/drug effects ; Glycogen Synthase Kinase 3/drug effects ; Glycogen Synthase Kinase 3/metabolism ; Humans ; Phosphorylation ; Proto-Oncogene Proteins c-bcl-2/drug effects ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Signal Transduction ; Skin Neoplasms/pathology ; TOR Serine-Threonine Kinases/drug effects ; TOR Serine-Threonine Kinases/metabolism ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction.
Autorzy:
Ueda S; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Tominaga T; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Ochi A; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Sakurai A; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Nishimura K; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Shibata E; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Wakino S; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Tamaki M; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Nagai K; Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 04; Vol. 11 (1), pp. 21643. Date of Electronic Publication: 2021 Nov 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cyclin-Dependent Kinase Inhibitor p16/*metabolism
Cyclin-Dependent Kinase Inhibitor p21/*metabolism
Transforming Growth Factor beta1/*metabolism
Animals ; Cell Line ; Cellular Senescence/physiology ; Cyclin-Dependent Kinase Inhibitor p15/metabolism ; Cyclin-Dependent Kinases/metabolism ; Endothelial Cells/metabolism ; Female ; Genes, p16/physiology ; Kidney/pathology ; Male ; Mice ; Mice, Inbred ICR ; Podocytes/metabolism ; Signal Transduction/physiology ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CDKN2A genetic testing in melanoma-prone families in Sweden in the years 2015-2020: implications for novel national recommendations.
Autorzy:
Pissa M; Department of Dermatology and Venereology, Ryhov County Hospital, Jönköping, Sweden.
Helkkula T; Department of Clinical Sciences, Division of Dermatology, Lund University Skin Cancer research group, Lund University, Lund, Sweden.; Department of Dermatology, Skåne University Hospital, Lund, Sweden.
Appelqvist F; Department of Dermatology, Institute of Clinical Sciences, Sahlgrenska University Hospital, Göteborg, Sweden.
Silander G; Department of Radiation Sciences, Division of Oncology, Umeå University, Umeå, Sweden.
Borg Å; Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Pettersson J; Department of Oncology, Ryhov County Hospital, Jönköping, Sweden.
Lapins J; Department of Dermatology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
Nielsen K; Department of Clinical Sciences, Division of Dermatology, Lund University Skin Cancer research group, Lund University, Lund, Sweden.; Department of Dermatology, Skåne University Hospital, Lund, Sweden.; Department of Dermatology, Helsingborg Hospital, Helsingborg, Sweden.
Höiom V; Department of Oncology and Pathology, Karolinska Institutet and Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Helgadottir H; Department of Oncology and Pathology, Karolinska Institutet and Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
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Źródło:
Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2021 Jul; Vol. 60 (7), pp. 888-896. Date of Electronic Publication: 2021 May 04.
Typ publikacji:
Journal Article
MeSH Terms:
Melanoma*/diagnosis
Melanoma*/epidemiology
Melanoma*/genetics
Skin Neoplasms*/epidemiology
Skin Neoplasms*/genetics
Cyclin-Dependent Kinase Inhibitor p16/genetics ; Genes, p16 ; Genetic Predisposition to Disease ; Genetic Testing ; Germ-Line Mutation ; Humans ; Sweden/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Histopathological image and gene expression pattern analysis for predicting molecular features and prognosis of head and neck squamous cell carcinoma.
Autorzy:
Chen L; Department of Biotherapy, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Zeng H; Department of Biotherapy, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Zhang M; West China School of Medicine, West China Hospital, Sichuan University, Chengdu, China.
Luo Y; West China School of Medicine, West China Hospital, Sichuan University, Chengdu, China.
Ma X; Department of Biotherapy, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
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Źródło:
Cancer medicine [Cancer Med] 2021 Jul; Vol. 10 (13), pp. 4615-4628. Date of Electronic Publication: 2021 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
Nomograms*
Head and Neck Neoplasms/*genetics
Head and Neck Neoplasms/*pathology
Squamous Cell Carcinoma of Head and Neck/*genetics
Squamous Cell Carcinoma of Head and Neck/*pathology
Area Under Curve ; Class I Phosphatidylinositol 3-Kinases/genetics ; DNA Methylation ; Female ; Gene Expression Profiling ; Genes, p16 ; Genes, p53 ; Head and Neck Neoplasms/mortality ; Histone-Lysine N-Methyltransferase/genetics ; Humans ; Machine Learning ; Male ; Middle Aged ; Mutation ; Prognosis ; Receptor, Notch1/genetics ; Squamous Cell Carcinoma of Head and Neck/mortality ; Tissue Array Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Identification of High-Risk Human Papillomavirus DNA, p16, and E6/E7 Oncoproteins in Laryngeal and Hypopharyngeal Squamous Cell Carcinomas.
Autorzy:
Lifsics A; Department of otolaryngology, Riga Stradiņš University, Pilsoņu 13, LV-1002 Riga, Latvia.
Groma V; Institute of Anatomy and Anthropology, Riga Stradiņš University, Kronvalda blvd 9, LV-1010 Riga, Latvia.
Cistjakovs M; Institute of Microbiology and Virology, Riga Stradiņš University, Rātsupītes 5, LV-1067 Riga, Latvia.
Skuja S; Institute of Anatomy and Anthropology, Riga Stradiņš University, Kronvalda blvd 9, LV-1010 Riga, Latvia.
Deksnis R; Department of Head and Neck Surgery, Oncology Centre of Latvia, Riga Eastern University Hospital, Hipokrāta 2, LV-1038 Riga, Latvia.
Murovska M; Institute of Microbiology and Virology, Riga Stradiņš University, Rātsupītes 5, LV-1067 Riga, Latvia.
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Źródło:
Viruses [Viruses] 2021 May 27; Vol. 13 (6). Date of Electronic Publication: 2021 May 27.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, p16*
DNA, Viral/*analysis
Head and Neck Neoplasms/*virology
Human papillomavirus 16/*genetics
Oncogene Proteins, Viral/*genetics
Papillomavirus E7 Proteins/*genetics
Repressor Proteins/*genetics
Squamous Cell Carcinoma of Head and Neck/*virology
Adult ; Aged ; Aged, 80 and over ; Female ; Head and Neck Neoplasms/classification ; Human papillomavirus 16/pathogenicity ; Humans ; Immunohistochemistry/methods ; Male ; Middle Aged ; Molecular Biology/methods ; Squamous Cell Carcinoma of Head and Neck/classification
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
CDKN2A Polymorphism in Melanoma Patients in Colombian Population: A Case-Control Study.
Autorzy:
Tovar-Parra JD; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
Gutiérrez-Castañeda LD; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
Gil-Quiñones SR; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
Nova JA; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
Pulido L; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Oct 10; Vol. 2020, pp. 7458917. Date of Electronic Publication: 2020 Oct 10 (Print Publication: 2020).
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Melanoma/*genetics
Skin Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Colombia ; Exons ; Female ; Gene Frequency ; Genes, p16 ; Genetic Predisposition to Disease ; Genetics, Population ; Genotype ; Haplotypes ; Heterozygote ; Homozygote ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular genetic changes in solid pseudopapillary neoplasms (SPN) of the pancreas.
Autorzy:
Rodriguez-Matta E; MS-2, Mayo Clinic CCATS Research Scholar, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Hemmerich A; Foundation Medicine, Morrisville, NC, USA.
Starr J; Division of Hematology Oncology, Mayo Clinic, Jacksonville, FL, USA.
Mody K; Division of Hematology Oncology, Mayo Clinic, Jacksonville, FL, USA.
Severson EA; Foundation Medicine, Morrisville, NC, USA.
Colon-Otero G; Division of Hematology Oncology, Mayo Clinic, Jacksonville, FL, USA.
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Źródło:
Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2020 Sep; Vol. 59 (9), pp. 1024-1027. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji:
Letter
MeSH Terms:
Point Mutation*
Cystadenocarcinoma, Papillary/*genetics
Pancreatic Neoplasms/*genetics
beta Catenin/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Female ; Genes, p16 ; Humans ; Male ; Middle Aged ; Young Adult
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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