Temat: "Genes, p16" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: High frequency of simultaneous loss of p16 and p16beta gene expression in squamous cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach.
Autorzy:: Hayashi K; Tokyo Women's Medical College, Japan.
Metzger R
Salonga D
Danenberg K
Leichman LP
Fink U
Sendler A
Kelsen D
Schwartz GK
Groshen S
Lenz HJ
Danenberg PV; Pokaż więcej
Źródło:: Oncogene [Oncogene] 1997 Sep 18; Vol. 15 (12), pp. 1481-8.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Genes, p16*
Transcription, Genetic*
Adenocarcinoma/*metabolism
Carcinoma, Squamous Cell/*genetics
Cyclin-Dependent Kinase Inhibitor p16/*biosynthesis
Esophageal Neoplasms/*metabolism
Stomach Neoplasms/*metabolism
Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Carcinoma, Squamous Cell/pathology ; DNA Primers ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/pathology ; Humans ; Polymerase Chain Reaction ; RNA, Messenger/biosynthesis ; Sequence Deletion ; Stomach Neoplasms/genetics ; Stomach Neoplasms/pathology

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Skocz do pozycji: 2.

Tytuł:: Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors.
Autorzy:: Kovar H; Children's Cancer Research Institute, St. Anna Kinderspital, Vienna, Austria.
Jug G
Aryee DN
Zoubek A
Ambros P
Gruber B
Windhager R
Gadner H; Pokaż więcej
Źródło:: Oncogene [Oncogene] 1997 Oct; Vol. 15 (18), pp. 2225-32.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Cycle Proteins*
Gene Deletion*
Genes, p16*
Proto-Oncogene Proteins*
Tumor Suppressor Proteins*
Retinoblastoma Protein/*physiology
Sarcoma, Ewing/*genetics
Sarcoma, Ewing/*pathology
Cell Cycle/physiology ; Cyclin D1/biosynthesis ; Cyclin-Dependent Kinase 4 ; Cyclin-Dependent Kinase Inhibitor p15 ; Cyclin-Dependent Kinase Inhibitor p16/biosynthesis ; Cyclin-Dependent Kinases/biosynthesis ; Gene Expression ; Genes, p53 ; Humans ; Mutation ; Prognosis ; Retinoblastoma Protein/biosynthesis ; Retinoblastoma Protein/genetics ; Sarcoma, Ewing/metabolism ; Transcription Factors/biosynthesis

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Skocz do pozycji: 3.

Tytuł:: Analysis of the CDKN2A, CDKN2B and CDK4 genes in 48 Australian melanoma kindreds.
Autorzy:: Flores JF; University of Southern California, Institute for Genetic Medical, Department of Biochemistry and Molecular Biology, Los Angeles 90033, USA.
Pollock PM
Walker GJ
Glendening JM
Lin AH
Palmer JM
Walters MK
Hayward NK
Fountain JW; Pokaż więcej
Źródło:: Oncogene [Oncogene] 1997 Dec 11; Vol. 15 (24), pp. 2999-3005.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Genes, p16/*genetics
Melanoma/*genetics
Alleles ; Alternative Splicing ; Australia ; Cyclin-Dependent Kinases/genetics ; DNA Mutational Analysis ; Disease Susceptibility ; Genetic Linkage ; Genetic Markers ; Genetic Testing ; Haplotypes ; Humans ; Mutation ; Pedigree ; Polymorphism, Single-Stranded Conformational ; Transcription, Genetic

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Skocz do pozycji: 4.

Tytuł:: Is mts1(S100A4) gene involved in the metastatic process modulated by gamma-interferon?
Autorzy:: Chiaramonte R; Dipartimento di Scienze e Tecnologie Biomediche, LITA, Università degli Studi di Milano, Italia.
Fasola S
Lollini PL
De Giovanni C
Comi P; Pokaż więcej
Źródło:: Pathobiology : journal of immunopathology, molecular and cellular biology [Pathobiology] 1998; Vol. 66 (1), pp. 38-40.
Typ publikacji:: Journal Article
MeSH Terms:: Genes, p16/*physiology
Interferon-gamma/*pharmacology
Neoplasm Metastasis/*genetics
Animals ; Blotting, Northern ; Genes, p16/drug effects ; Mammary Neoplasms, Animal/secondary ; Melanoma, Experimental/secondary ; Mice ; Tumor Cells, Cultured

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Skocz do pozycji: 5.

Tytuł:: Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells.
Autorzy:: Drexler HG; DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Cultures, Braunschweig, Germany.; Pokaż więcej
Źródło:: Leukemia [Leukemia] 1998 Jun; Vol. 12 (6), pp. 845-59.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cell Cycle Proteins*
Cyclin-Dependent Kinase Inhibitor p16*
Enzyme Inhibitors*
Genes, Tumor Suppressor*
Genes, p16*
Tumor Suppressor Proteins*
Carrier Proteins/*genetics
Leukemia/*genetics
Lymphoma/*genetics
Adult ; Cyclin-Dependent Kinase Inhibitor p15 ; Cyclin-Dependent Kinase Inhibitor p18 ; DNA Methylation ; Gene Deletion ; Genes, Retinoblastoma ; Genes, p53 ; Humans

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Skocz do pozycji: 6.

Tytuł:: Hypermethylation of p15/ink4b/MTS2 gene is differentially implicated among non-Hodgkin's lymphomas.
Autorzy:: Martinez-Delgado B; Genetic Department, Fundacion Jimenez Diaz, Madrid, Spain.
Robledo M
Arranz E
Osorio A
García MJ
Echezarreta G
Rivas C
Benitez J; Pokaż więcej
Źródło:: Leukemia [Leukemia] 1998 Jun; Vol. 12 (6), pp. 937-41.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Cycle Proteins*
Cyclin-Dependent Kinase Inhibitor p16*
DNA Methylation*
Genes, Tumor Suppressor*
Tumor Suppressor Proteins*
Carrier Proteins/*genetics
Lymphoma, Non-Hodgkin/*genetics
Cyclin-Dependent Kinase Inhibitor p15 ; Genes, p16 ; Humans ; Lymphoma, B-Cell, Marginal Zone/genetics

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Skocz do pozycji: 7.

Tytuł:: Homozygous deletions of methylthioadenosine phosphorylase (MTAP) are more frequent than p16INK4A (CDKN2) homozygous deletions in primary non-small cell lung cancers (NSCLC).
Autorzy:: Schmid M; Stein Institute for Research on Aging, University of California, San Diego, La Jolla 92093, USA.
Malicki D
Nobori T
Rosenbach MD
Campbell K
Carson DA
Carrera CJ; Pokaż więcej
Źródło:: Oncogene [Oncogene] 1998 Nov 19; Vol. 17 (20), pp. 2669-75.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Gene Deletion*
Genes, Tumor Suppressor*
Genes, p16*
Carcinoma, Non-Small-Cell Lung/*genetics
Chromosomes, Human, Pair 9/*genetics
DNA, Neoplasm/*genetics
Lung Neoplasms/*genetics
Neoplasm Proteins/*genetics
Purine-Nucleoside Phosphorylase/*genetics
DNA Primers ; Homozygote ; Humans ; Male ; Polymerase Chain Reaction ; Pseudogenes

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Skocz do pozycji: 8.

Tytuł:: Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression.
Autorzy:: Vonlanthen S; Department of Clinical Research, University of Bern, Switzerland.
Heighway J
Tschan MP
Borner MM
Altermatt HJ
Kappeler A
Tobler A
Fey MF
Thatcher N
Yarbrough WG
Betticher DC; Pokaż więcej
Źródło:: Oncogene [Oncogene] 1998 Nov 26; Vol. 17 (21), pp. 2779-85.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Genes, Tumor Suppressor*
Genes, p16*
Genes, p53*
Carcinoma, Non-Small-Cell Lung/*genetics
Cyclin-Dependent Kinase Inhibitor p16/*biosynthesis
DNA, Neoplasm/*genetics
Lung Neoplasms/*genetics
Neoplasm Proteins/*biosynthesis
Proteins/*genetics
Tumor Suppressor Protein p53/*biosynthesis
Aged ; Animals ; COS Cells ; Carcinoma, Non-Small-Cell Lung/pathology ; Cyclin D1/metabolism ; DNA Methylation ; Exons/genetics ; Female ; G1 Phase/genetics ; Genes, Overlapping ; HeLa Cells ; Humans ; K562 Cells ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Proteins/genetics ; RNA, Messenger/biosynthesis ; RNA, Neoplasm/biosynthesis ; Retinoblastoma Protein/biosynthesis ; Retinoblastoma Protein/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Cells, Cultured ; Tumor Suppressor Protein p14ARF

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Skocz do pozycji: 9.

Tytuł:: Early acquisition of homozygous deletions of p16/p19 during squamous cell carcinogenesis and genetic mosaicism in bladder cancer.
Autorzy:: Tsutsumi M; Department of Biochemistry and Molecular Biology, University of Southern California, School of Medicine, Los Angeles 90033, USA.
Tsai YC
Gonzalgo ML
Nichols PW
Jones PA; Pokaż więcej
Źródło:: Oncogene [Oncogene] 1998 Dec 10; Vol. 17 (23), pp. 3021-7.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Cell Cycle Proteins*
Chromosomes, Human, Pair 9*
Cyclin-Dependent Kinase Inhibitor p16*
Gene Deletion*
Genes, p16*
Carcinoma, Transitional Cell/*genetics
Carrier Proteins/*genetics
Mosaicism/*genetics
Neoplasms, Squamous Cell/*genetics
Urinary Bladder Neoplasms/*genetics
Carcinoma, Transitional Cell/pathology ; Cyclin-Dependent Kinase Inhibitor p19 ; DNA Methylation ; Homozygote ; Humans ; Loss of Heterozygosity ; Neoplasms, Squamous Cell/pathology ; Promoter Regions, Genetic ; Urinary Bladder Neoplasms/pathology

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Skocz do pozycji: 10.

Tytuł:: The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer.
Autorzy:: Tsihlias J; Department of Urology, Sunnybrook Health Science Centre, University of Toronto, Ontario, Canada.
Kapusta L
Slingerland J; Pokaż więcej
Źródło:: Annual review of medicine [Annu Rev Med] 1999; Vol. 50, pp. 401-23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Cell Cycle Proteins*
Cyclin-Dependent Kinase Inhibitor p16*
Tumor Suppressor Proteins*
Cyclin-Dependent Kinases/*antagonists & inhibitors
Enzyme Inhibitors/*analysis
Neoplasms/*pathology
Breast Neoplasms/pathology ; Carcinoma/pathology ; Carrier Proteins/genetics ; Cell Cycle ; Colonic Neoplasms/pathology ; Coloring Agents ; Cyclin-Dependent Kinase Inhibitor p15 ; Cyclin-Dependent Kinase Inhibitor p27 ; Cyclins/analysis ; Female ; Gene Deletion ; Genes, Tumor Suppressor/genetics ; Genes, p16/genetics ; Homozygote ; Humans ; Immunohistochemistry ; Leukemia/genetics ; Male ; Microtubule-Associated Proteins/analysis ; Prognosis ; Prospective Studies ; Prostatic Neoplasms/pathology ; Stomach Neoplasms/pathology

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Skocz do pozycji: 11.

Tytuł:: DNA methylation in the promoter region of the p16 (CDKN2/MTS-1/INK4A) gene in human breast tumours.
Autorzy:: Woodcock DM; Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia.
Linsenmeyer ME
Doherty JP
Warren WD; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 1999 Jan; Vol. 79 (2), pp. 251-6.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Methylation*
Breast Neoplasms/*genetics
Genes, p16/*genetics
Promoter Regions, Genetic/*genetics
Female ; Humans ; Molecular Sequence Data ; Sequence Alignment ; Sequence Analysis, DNA