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Wyszukujesz frazę ""Genes, p53"" wg kryterium: Temat


Tytuł:
Fluorometric determination of the p53 cancer gene using strand displacement amplification on gold nanoparticles.
Autorzy:
Zhao W; Key Laboratory of Functional Small Organic Molecule, Ministry of Education, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022, People's Republic of China.
Li H; Key Laboratory of Functional Small Organic Molecule, Ministry of Education, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022, People's Republic of China. .; State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University, Changsha, 410082, People's Republic of China. .
Tang Y; Key Laboratory of Functional Small Organic Molecule, Ministry of Education, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022, People's Republic of China.
Liu M; Key Laboratory of Functional Small Organic Molecule, Ministry of Education, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022, People's Republic of China.
Wang S; Key Laboratory of Functional Small Organic Molecule, Ministry of Education, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022, People's Republic of China. .
Yu R; State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering Hunan University, Changsha, 410082, People's Republic of China. .
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Źródło:
Mikrochimica acta [Mikrochim Acta] 2019 Jul 06; Vol. 186 (8), pp. 517. Date of Electronic Publication: 2019 Jul 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genes, p53*
Nucleic Acid Amplification Techniques*
Gold/*chemistry
Metal Nanoparticles/*chemistry
A549 Cells ; Fluorometry ; Humans ; Neoplasms/genetics
Czasopismo naukowe
Tytuł:
Yolk Sac Tumor in a Recurrence of Colonic Adenocarcinoma With Shared Mutations in APC and TP53 Genes: A Case Report.
Autorzy:
Otani T; Kindai University Faculty of Medicine, Osaka-sayama, Japan.; 326473Kindai University Hospital, Osaka-sayama, Japan.
Kanemura H; Kindai University Faculty of Medicine, Osaka-sayama, Japan.
Kimura M; 326473Kindai University Hospital, Osaka-sayama, Japan.
Mitani S; Kindai University Faculty of Medicine, Osaka-sayama, Japan.
Takeda M; Kindai University Faculty of Medicine, Osaka-sayama, Japan.
Matsuki M; Kindai University Faculty of Medicine, Osaka-sayama, Japan.
Matsumura N; Kindai University Faculty of Medicine, Osaka-sayama, Japan.
Satou T; 326473Kindai University Hospital, Osaka-sayama, Japan.
Nakagawa K; Kindai University Faculty of Medicine, Osaka-sayama, Japan.
Ito A; Kindai University Faculty of Medicine, Osaka-sayama, Japan.
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Źródło:
International journal of surgical pathology [Int J Surg Pathol] 2022 Sep; Vol. 30 (6), pp. 646-651. Date of Electronic Publication: 2022 Jan 05.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Adenocarcinoma*/genetics
Adenocarcinoma*/pathology
Colonic Neoplasms*/genetics
Endodermal Sinus Tumor*/diagnosis
Endodermal Sinus Tumor*/genetics
Endodermal Sinus Tumor*/pathology
Pelvic Neoplasms*
Female ; Genes, p53 ; Humans ; Middle Aged ; Mutation ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
Mutant p53 drives an immune cold tumor immune microenvironment in oral squamous cell carcinoma.
Autorzy:
Shi Y; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA.; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.
Xie T; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA.
Wang B; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA.
Wang R; Department of Endodontics, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Cai Y; Department of Oral & Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Yuan B; Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Gleber-Netto FO; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA.
Tian X; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Rodriguez-Rosario AE; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA.; Department of Biology, University of Puerto Rico, Bayamon, Puerto Rico, USA.
Osman AA; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA.
Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Pickering CR; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA.
Ren X; Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.
Sikora AG; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA.
Myers JN; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA. .
Rangel R; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 7030, USA. .
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Źródło:
Communications biology [Commun Biol] 2022 Jul 28; Vol. 5 (1), pp. 757. Date of Electronic Publication: 2022 Jul 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Squamous Cell*/genetics
Head and Neck Neoplasms*/genetics
Mouth Neoplasms*/genetics
Mouth Neoplasms*/pathology
Mouth Neoplasms*/therapy
Genes, p53 ; Humans ; Squamous Cell Carcinoma of Head and Neck/genetics ; Tumor Microenvironment/genetics ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł:
Comparative Analysis of Gene Correlation Networks of Breast Cancer Patients Based on Mutations in TP53.
Autorzy:
Park B; Department of Bioinformatics, Ichrogene Incorporated, Suwon 16229, Korea.; Department of Computer Engineering, Inha University, Incheon 22212, Korea.
Im J; Department of Computer Engineering, Inha University, Incheon 22212, Korea.; Data Infomation Platform, Kakao Corporation, Seongnam 13494, Korea.
Han K; Department of Computer Engineering, Inha University, Incheon 22212, Korea.
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Źródło:
Biomolecules [Biomolecules] 2022 Jul 13; Vol. 12 (7). Date of Electronic Publication: 2022 Jul 13.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/therapy
Triple Negative Breast Neoplasms*/genetics
Female ; Genes, p53 ; Humans ; Mutation ; Proportional Hazards Models ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
TP53 Variant in the Blood of a Patient with Gastric Cancer Undergoing Tumor Profiling Tests Diagnosed as Clonal Hematopoiesis.
Autorzy:
Kawai M; Department of Clinical Genetics, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.
Iijima-Yamashita Y; Department of Advanced Diagnosis, Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.
Taguchi I; Department of Clinical Genetics, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.
Kataoka M; Department of Surgery, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.
Sanada M; Department of Advanced Diagnosis, Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.
Murakami Y; Department of Pathology, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.
Kitagawa C; Department of Medical Oncology, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.
Hattori H; Department of Clinical Genetics, National Hospital Organization Nagoya Medical Center, Nagoya, Aichi, Japan.
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Źródło:
The American journal of case reports [Am J Case Rep] 2022 Jun 14; Vol. 23, pp. e936455. Date of Electronic Publication: 2022 Jun 14.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Li-Fraumeni Syndrome*/diagnosis
Li-Fraumeni Syndrome*/genetics
Li-Fraumeni Syndrome*/pathology
Stomach Neoplasms*/diagnosis
Stomach Neoplasms*/genetics
Clonal Hematopoiesis ; Genes, p53/genetics ; Genetic Predisposition to Disease ; Humans ; Male ; Middle Aged ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
TP53 and TP53-associated genes are correlated with the prognosis of paediatric neuroblastoma.
Autorzy:
Wang H; Medical Research Center, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China. .
Wang X; Medical Research Center, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.
Xu L; Medical Research Center, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China.
Zhang J; State Key Laboratory for Medical Genomics, Shanghai Institute of Hematology, Rui-Jin Hospital Affiliated to School of Medicine, Shanghai Jiao Tong University, Shanghai, China. .
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Źródło:
BMC genomic data [BMC Genom Data] 2022 Jun 02; Vol. 23 (1), pp. 41. Date of Electronic Publication: 2022 Jun 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*/genetics
Neuroblastoma*/genetics
Child ; Genes, p53 ; Humans ; N-Myc Proto-Oncogene Protein/genetics ; Prognosis ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
Establishment of TP53-knockout canine cells using optimized CRIPSR/Cas9 vector system for canine cancer research.
Autorzy:
Eun K; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Park MG; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Jeong YW; Sooam Biotech Research Foundation, 64 Kyungin-ro, Guro-gu, Seoul, 08359, Republic of Korea.
Jeong YI; Sooam Biotech Research Foundation, 64 Kyungin-ro, Guro-gu, Seoul, 08359, Republic of Korea.
Hyun SH; Laboratory of Veterinary Embryology and Biotechnology, College of Veterinary Medicine, Chungbuk National University, Cheongju, 28644, Republic of Korea.
Hwang WS; Sooam Biotech Research Foundation, 64 Kyungin-ro, Guro-gu, Seoul, 08359, Republic of Korea.
Kim SH; Department of Animal Science, College of Agriculture and Life Sciences, Chonnam National University, Gwangju, 61186, Republic of Korea. .; Gwangju Center, Korea Basic Science Institute, Gwangju, 61186, Republic of Korea. .
Kim H; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea. .
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Źródło:
BMC biotechnology [BMC Biotechnol] 2019 Jan 03; Vol. 19 (1), pp. 1. Date of Electronic Publication: 2019 Jan 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CRISPR-Cas Systems*
Genes, p53*
Gene Editing/*methods
Gene Knockout Techniques/*methods
Neoplasms/*genetics
Neoplasms/*veterinary
Animals ; Animals, Genetically Modified ; Dogs ; Fibroblasts/physiology ; Male ; Neoplasms/prevention & control
Czasopismo naukowe
Tytuł:
Is nestin a diagnostic marker for combined hepatocellular-cholangiocarcinoma?
Autorzy:
Sasaki M; Department of Human Pathology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
Sato Y; Department of Human Pathology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
Nakanuma Y; Division of Pathology, Fukui Saiseikai Hospital, Fukui, Japan.
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Źródło:
Histopathology [Histopathology] 2022 Apr; Vol. 80 (5), pp. 859-868. Date of Electronic Publication: 2022 Mar 03.
Typ publikacji:
Journal Article
MeSH Terms:
Bile Duct Neoplasms/*diagnosis
Biomarkers, Tumor/*analysis
Carcinoma, Hepatocellular/*diagnosis
Cholangiocarcinoma/*diagnosis
Liver Neoplasms/*diagnosis
Nestin/*analysis
Adult ; Aged ; Bile Duct Neoplasms/genetics ; Bile Duct Neoplasms/pathology ; Biomarkers, Tumor/genetics ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Cholangiocarcinoma/genetics ; Cholangiocarcinoma/pathology ; Female ; Genes, p53/genetics ; Humans ; Immunohistochemistry ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Male ; Middle Aged ; Mutation ; Neoplasm Grading ; Nestin/genetics
Czasopismo naukowe
Tytuł:
TP53 Gene Therapy as a Potential Treatment for Patients with COVID-19.
Autorzy:
Harford JB; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA.
Kim SS; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA.; Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA.
Pirollo KF; Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA.
Chang EH; Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA.
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Źródło:
Viruses [Viruses] 2022 Mar 31; Vol. 14 (4). Date of Electronic Publication: 2022 Mar 31.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/therapy
Viruses*/metabolism
Genes, p53 ; Genetic Therapy ; Humans ; Immunity, Innate ; Pandemics ; SARS-CoV-2/genetics ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł:
Li-Fraumeni syndrome in Tunisian carriers with different and rare tumor phenotype: genotype-phenotype correlation.
Autorzy:
Sassi H; Department of Congenital and Hereditary Diseases, Charles Nicolle Hospital, University Tunis El Manar, 1006, Tunis, Tunisia. .
Meddeb R; Department of Congenital and Hereditary Diseases, Charles Nicolle Hospital, University Tunis El Manar, 1006, Tunis, Tunisia. meddeb_.; Laboratory of Human Genetics LR99ES10, Faculty of Medicine of Tunis, University Tunis El Manar, 1006, Tunis, Tunisia. meddeb_.
Cherif MA; Department of Radiation Oncology, Salah Azaiez Institute, University Tunis El Manar, 1006, Tunis, Tunisia.
Nasr C; Department of Radiation Oncology, Salah Azaiez Institute, University Tunis El Manar, 1006, Tunis, Tunisia.
Riahi A; Institute of Applied Biological Sciences of Tunis, University Tunis El Manar, Tunis, Tunisia.
Hannachi S; Laboratory of Pathology Anatomy and Cytology, Tunis, Tunisia.
Belguith N; Department of Congenital and Hereditary Diseases, Charles Nicolle Hospital, University Tunis El Manar, 1006, Tunis, Tunisia.
M'rad R; Department of Congenital and Hereditary Diseases, Charles Nicolle Hospital, University Tunis El Manar, 1006, Tunis, Tunisia.; Laboratory of Human Genetics LR99ES10, Faculty of Medicine of Tunis, University Tunis El Manar, 1006, Tunis, Tunisia.
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Źródło:
BMC medical genomics [BMC Med Genomics] 2022 Mar 04; Vol. 15 (1), pp. 44. Date of Electronic Publication: 2022 Mar 04.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Li-Fraumeni Syndrome*/diagnosis
Li-Fraumeni Syndrome*/epidemiology
Li-Fraumeni Syndrome*/genetics
Adult ; Female ; Genes, p53 ; Genetic Association Studies ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Humans ; Phenotype ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
Prognosis of Tumor Microenvironment in Luminal B-Type Breast Cancer.
Autorzy:
Lv J; Department of Surgery, The First Hospital of Qinhuangdao, Qinhuangdao City, Hebei Province, China.
Ren J; Department of Surgery, The First Hospital of Qinhuangdao, Qinhuangdao City, Hebei Province, China.
Zheng J; Department of Surgery, The First Hospital of Qinhuangdao, Qinhuangdao City, Hebei Province, China.
Zhang F; Department of Surgery, The First Hospital of Qinhuangdao, Qinhuangdao City, Hebei Province, China.
Han M; Department of Surgery, The First Hospital of Qinhuangdao, Qinhuangdao City, Hebei Province, China.
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Źródło:
Disease markers [Dis Markers] 2022 Feb 10; Vol. 2022, pp. 5621441. Date of Electronic Publication: 2022 Feb 10 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Databases, Genetic*
Gene Expression Profiling*
Prognosis*
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Breast Neoplasms/*genetics
Aged ; Breast Neoplasms/immunology ; Breast Neoplasms/pathology ; Female ; Genes, p53 ; Humans ; Immunotherapy ; Middle Aged ; Mutation/genetics ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł:
Potential Effects of Metformin on the Vitality, Invasion, and Migration of Human Vascular Smooth Muscle Cells via Downregulating lncRNA-ATB.
Autorzy:
Jia W; Department of Vascular Surgery, Beijing Jishuitan Hospital, Beijing, China.
Zhou Y; Department of Neurological Rehabilitation, Weifang Yidu Central Hospital, Weifang, China.
Sun L; Emergency Center, Qingdao Central Hospital Affiliated to Qingdao University, Qingdao, China.
Liu J; Department of Vascular Surgery, Beijing Jishuitan Hospital, Beijing, China.
Cheng Z; Department of Vascular Surgery, Beijing Jishuitan Hospital, Beijing, China.
Zhao S; Guangdong Academy of Medical Sciences and Guangdong Provincial People's Hospital, Guangzhou, China.
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Źródło:
Disease markers [Dis Markers] 2022 Jan 04; Vol. 2022, pp. 7480199. Date of Electronic Publication: 2022 Jan 04 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Muscle, Smooth, Vascular*/drug effects
Muscle, Smooth, Vascular*/metabolism
Metformin/*pharmacology
RNA, Long Noncoding/*genetics
Coronary Disease/metabolism ; Down-Regulation ; Genes, p53 ; Humans ; RNA, Long Noncoding/blood
Czasopismo naukowe
Tytuł:
Revisiting the indication for prophylactic contralateral mastectomy in patients with Li-Fraumeni syndrome and breast cancer. Case report
Autorzy:
Briceño-Morales X; Instituto Nacional de Cancerología, Bogotá (Colombia).. .
Briceño-Morales C; Instituto Nacional de Cancerología, Bogotá (Colombia).. .
Guerrero-Macías SI; Instituto Nacional de Cancerología, Bogotá (Colombia).. .
Pedroza-Durán AM; Instituto Nacional de Cancerología, Bogotá (Colombia).. anny_.
Súarez-Rodríguez RA; Instituto Nacional de Cancerología, Bogotá (Colombia).. .
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Transliterated Title:
Revisitando la indicación de la mastectomía profiláctica contralateral en pacientes con Síndrome de Li-Fraumeni y cáncer de mama. Reporte de un caso
Źródło:
Revista colombiana de obstetricia y ginecologia [Rev Colomb Obstet Ginecol] 2021 Sep 30; Vol. 72 (3), pp. 307-318. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/prevention & control
Breast Neoplasms*/surgery
Li-Fraumeni Syndrome*/genetics
Li-Fraumeni Syndrome*/surgery
Prophylactic Mastectomy*
Adult ; Female ; Genes, p53/genetics ; Humans ; Mastectomy
Czasopismo naukowe
Tytuł:
Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark.
Autorzy:
Stoltze U; Clinical Genetics Dept., Rigshospitalet, Copenhagen, Denmark.; Pediatric Oncology Laboratory, Rigshospitalet, Copenhagen, Denmark.
Skytte AB; Clinical Genetics Dept., Aarhus University Hospital, Aarhus, Denmark.
Roed H; Clinical Genetics Dept., Odense University Hospital, Odensen, Denmark.
Hasle H; Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.
Ejlertsen B; Oncology Clinic, Finsen Center Rigshospitalet, Copenhagen, Denmark.
Overeem Hansen TV; Center of Genomic Medicine, Rigshospitalet, Copenhagen, Denmark.
Schmiegelow K; Pediatric Oncology Laboratory, Rigshospitalet, Copenhagen, Denmark.
Gerdes AM; Clinical Genetics Dept., Rigshospitalet, Copenhagen, Denmark.
Wadt K; Clinical Genetics Dept., Rigshospitalet, Copenhagen, Denmark.
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Źródło:
PloS one [PLoS One] 2018 Jan 11; Vol. 13 (1), pp. e0190050. Date of Electronic Publication: 2018 Jan 11 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genes, p53*
Germ-Line Mutation*
Pedigree*
Registries*
Adolescent ; Adult ; Child ; Child, Preschool ; Denmark ; Female ; Humans ; Infant ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł:
Ingenol mebutate treatment for actinic cheilitis: clinical, histopathological and p53 profile of 14 cases.
Autorzy:
Rossini RC; Department of Dermatology, Santa Casa de Curitiba Hospital, Paraná, Brazil.
Dellatorre G; Department of Dermatology, Santa Casa de Curitiba Hospital, Paraná, Brazil.
Mesquita LAF; Department of Dermatology, Santa Casa de Curitiba Hospital, Paraná, Brazil.
Tarlé RG; Department of Dermatology, Santa Casa de Curitiba Hospital, Paraná, Brazil.; The Pontifical Catholic University of Paraná, Curitiba, Brazil.
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Źródło:
The Journal of dermatological treatment [J Dermatolog Treat] 2021 Dec; Vol. 32 (8), pp. 1049-1052. Date of Electronic Publication: 2020 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Cheilitis*/drug therapy
Diterpenes*/therapeutic use
Keratosis, Actinic*/drug therapy
Genes, p53 ; Humans ; Treatment Outcome ; Tumor Suppressor Protein p53
SCR Disease Name:
Actinic cheilitis
Czasopismo naukowe
Tytuł:
Clinico-genomic profiling and clonal dynamic modeling of TP53 -aberrant myelodysplastic syndrome and acute myeloid leukemia.
Autorzy:
Patel SA; Department of Medicine-Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
Lloyd MR; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Cerny J; Department of Medicine-Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
Shi Q; Department of Medicine-Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.; Department of Population & Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Simin K; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
Ediriwickrema A; Division of Hematology, Department of Medicine, Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Hutchinson L; Department of Pathology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
Miron PM; Department of Pathology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
Higgins AW; Department of Pathology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
Ramanathan M; Department of Medicine-Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
Gerber JM; Department of Medicine-Hematology & Oncology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2021 Dec; Vol. 62 (14), pp. 3348-3360. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/diagnosis
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/therapy
Myelodysplastic Syndromes*/diagnosis
Myelodysplastic Syndromes*/genetics
Myelodysplastic Syndromes*/therapy
Genes, p53 ; Genetic Profile ; Humans ; Mutation ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study.
Autorzy:
Kawakami S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Takano S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan. .
Fukasawa M; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Shindo H; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Takahashi E; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Fukasawa Y; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Hayakawa H; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kuratomi N; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Kadokura M; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Hosomura N; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Amemiya H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Kawaida H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Kono H; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Maekawa S; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Ichikawa D; First Department of Surgery, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Enomoto N; First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
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Źródło:
BMC cancer [BMC Cancer] 2021 Nov 19; Vol. 21 (1), pp. 1245. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji:
Journal Article
MeSH Terms:
Mutation*
Gallbladder Neoplasms/*genetics
Genes, p53/*genetics
Pancreaticobiliary Maljunction/*genetics
Adult ; Aged ; Case-Control Studies ; Cholecystitis/genetics ; Female ; Gene Expression Profiling ; Genes, Retinoblastoma ; Genes, erbB-1 ; Genes, erbB-2 ; Genes, ras ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Mutation Accumulation ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł:
Identification of Mutator-Derived lncRNA Signatures of Genomic Instability for Promoting the Clinical Outcome in Hepatocellular Carcinoma.
Autorzy:
Tang X; The First Clinical Medical College, Lanzhou University, Lanzhou City, Gansu Province, China.; The Second Department of Gastrointestinal Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong City, Sichuan Province, China.
Miao Y; The First Clinical Medical College, Lanzhou University, Lanzhou City, Gansu Province, China.
Wang J; The First Clinical Medical College, Lanzhou University, Lanzhou City, Gansu Province, China.
Cai T; The First Clinical Medical College, Lanzhou University, Lanzhou City, Gansu Province, China.
Yang L; Gansu Academy of Traditional Chinese Medicine, Lanzhou City, Gansu Province, China.
Mi D; The First Clinical Medical College, Lanzhou University, Lanzhou City, Gansu Province, China.; Gansu Academy of Traditional Chinese Medicine, Lanzhou City, Gansu Province, China.
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Źródło:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2021 Nov 11; Vol. 2021, pp. 1205029. Date of Electronic Publication: 2021 Nov 11 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Genomic Instability*
Carcinoma, Hepatocellular/*genetics
Liver Neoplasms/*genetics
RNA, Long Noncoding/*genetics
Biomarkers, Tumor/genetics ; Carcinoma, Hepatocellular/pathology ; Carrier Proteins/genetics ; Computational Biology ; Female ; Genes, p53 ; Humans ; Liver Neoplasms/pathology ; Male ; Models, Genetic ; Mutation ; Nomograms ; Nuclear Proteins/genetics ; Prognosis ; Proportional Hazards Models ; Regression Analysis ; Risk Factors
Czasopismo naukowe
Tytuł:
Design, Synthesis and Evaluation of Novel Derivatives of Curcuminoids with Cytotoxicity.
Autorzy:
Chen CY; School of Pharmacy, China Medical University, No. 100, Sec. 1, Jingmao Road, Beitun Dist., Taichung 406040, Taiwan.
Lien JC; School of Pharmacy, China Medical University, No. 100, Sec. 1, Jingmao Road, Beitun Dist., Taichung 406040, Taiwan.
Chen CY; School of Pharmacy, China Medical University, No. 100, Sec. 1, Jingmao Road, Beitun Dist., Taichung 406040, Taiwan.
Hung CC; School of Pharmacy, China Medical University, No. 100, Sec. 1, Jingmao Road, Beitun Dist., Taichung 406040, Taiwan.; Department of Pharmacy, China Medical University Hospital, 2 Yude Road, Taichung 40447, Taiwan.
Lin HC; School of Pharmacy, China Medical University, No. 100, Sec. 1, Jingmao Road, Beitun Dist., Taichung 406040, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 10; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 10.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Design*
Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Diarylheptanoids/*chemistry
Diarylheptanoids/*pharmacology
Antigens, Differentiation/chemistry ; Antigens, Differentiation/metabolism ; Antineoplastic Agents/chemical synthesis ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Diarylheptanoids/chemical synthesis ; Drug Screening Assays, Antitumor ; Gene Expression/drug effects ; Gene Expression Regulation/drug effects ; Genes, p53/drug effects ; Humans ; Ketones/chemistry ; Ketones/pharmacology ; Molecular Docking Simulation ; Principal Component Analysis ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
Resistance to inflammation underlies enhanced fitness in clonal hematopoiesis.
Autorzy:
Avagyan S; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
Henninger JE; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
Mannherz WP; Harvard Medical School, Boston, MA, USA.
Mistry M; Harvard Chan Bioinformatics Core, Boston, MA, USA.
Yoon J; Harvard Chan Bioinformatics Core, Boston, MA, USA.
Yang S; Boston Children's Hospital, Boston, MA, USA.
Weber MC; Boston Children's Hospital, Boston, MA, USA.
Moore JL; Boston Children's Hospital, Boston, MA, USA.
Zon LI; Boston Children's Hospital, Boston, MA, USA.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2021 Nov 05; Vol. 374 (6568), pp. 768-772. Date of Electronic Publication: 2021 Nov 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Clonal Hematopoiesis*
Inflammation*/genetics
Hematopoietic Stem Cells/*physiology
Myeloid Cells/*physiology
Animals ; CRISPR-Cas Systems ; Cytokines/genetics ; Cytokines/metabolism ; DNA (Cytosine-5-)-Methyltransferases/genetics ; Frameshift Mutation ; Genes, p53 ; Mutation ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics ; Nuclear Receptor Subfamily 4, Group A, Member 1/metabolism ; RNA-Seq ; Repressor Proteins/genetics ; Selection, Genetic ; Single-Cell Analysis ; Zebrafish/embryology ; Zebrafish/genetics ; Zebrafish Proteins/genetics
Czasopismo naukowe

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