Temat: "Genes, p53" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Mutant p53 Gain-of-Function Induces Migration and Invasion through Overexpression of miR-182-5p in Cancer Cells.
Autorzy:: Madrigal T; Unidad de Investigación en Cáncer, Instituto de Investigaciones Biomédicas-Universidad Nacional Autónoma de México, Instituto Nacional de Cancerología, San Fernando 22, Sección XVI, Tlalpan, CDMX, Mexico City 14080, Mexico.; Departamento de Ciencias Biológicas y de la Salud, UAM Iztapalapa, Mexico City 09340, Mexico.
Ortega-Bernal D; Departamento de Atención a la Salud, UAM Xochimilco, Mexico City 04960, Mexico.; Departamento de Ciencias Naturales, Unidad Cuajimalpa, Universidad Autonóma Metropolitana, Mexico City 05348, Mexico.
Herrera LA; Unidad de Investigación en Cáncer, Instituto de Investigaciones Biomédicas-Universidad Nacional Autónoma de México, Instituto Nacional de Cancerología, San Fernando 22, Sección XVI, Tlalpan, CDMX, Mexico City 14080, Mexico.; Escuela de Medicina y Ciencias de la Salud-Tecnológico de Monterrey, Mexico City 14380, Mexico.
González-De la Rosa CH; Departamento de Ciencias Naturales, Unidad Cuajimalpa, Universidad Autonóma Metropolitana, Mexico City 05348, Mexico.
Domínguez-Gómez G; Subdirección de Investigación Clínica, Instituto Nacional de Cancerología, Mexico City 14080, Mexico.
Aréchaga-Ocampo E; Departamento de Ciencias Naturales, Unidad Cuajimalpa, Universidad Autonóma Metropolitana, Mexico City 05348, Mexico.
Díaz-Chávez J; Unidad de Investigación en Cáncer, Instituto de Investigaciones Biomédicas-Universidad Nacional Autónoma de México, Instituto Nacional de Cancerología, San Fernando 22, Sección XVI, Tlalpan, CDMX, Mexico City 14080, Mexico.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Oct 23; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genes, p53*
MicroRNAs*/metabolism
Humans ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Cell Line, Tumor ; Gain of Function Mutation ; Cell Proliferation ; Neoplastic Processes ; Forkhead Transcription Factors/metabolism ; Microfilament Proteins/metabolism ; Neoplasm Proteins/metabolism

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Skocz do pozycji: 2.

Tytuł:: Accurate interpretation of p53 immunohistochemical patterns is a surrogate biomarker for TP53 alterations in large B-cell lymphoma.
Autorzy:: Li X; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Luo D; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhang L; Cancer Center, Union Hospital, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Li Q; Cancer Center, Union Hospital, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Fan J; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhang J; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Huang B; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Yang M; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Nie X; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Chang X; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
Pan H; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2023 Oct 19; Vol. 23 (1), pp. 1008. Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:: Journal Article
MeSH Terms:: Genes, p53*
Lymphoma, B-Cell*/genetics
Humans ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Reproducibility of Results ; In Situ Hybridization, Fluorescence ; Mutation ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism

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Skocz do pozycji: 3.

Tytuł:: Pediatric-type high-grade gliomas with PDGFRA amplification in adult patients with Li-Fraumeni syndrome: clinical and molecular characterization of three cases.
Autorzy:: Kibe Y; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Ohka F; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. .
Aoki K; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Yamaguchi J; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Motomura K; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Ito E; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Takeuchi K; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Nagata Y; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Ito S; Department of Neurosurgery, Konan Kosei Hospital, 137 Oomatsubara, Takaya-cho, Konan, 483-8703, Japan.
Mizutani N; Department of Neurosurgery, Konan Kosei Hospital, 137 Oomatsubara, Takaya-cho, Konan, 483-8703, Japan.
Shiba Y; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Maeda S; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Nishikawa T; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Shimizu H; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Saito R; Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.; Pokaż więcej
Źródło:: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Apr 11; Vol. 12 (1), pp. 57. Date of Electronic Publication: 2024 Apr 11.
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/genetics
Glioblastoma*/pathology
Li-Fraumeni Syndrome*/genetics
Brain Neoplasms*/genetics
Brain Neoplasms*/pathology
Glioma*/genetics
Glioma*/pathology
Cerebellar Neoplasms*/genetics
Adult ; Humans ; Child ; Genes, p53 ; Mutation/genetics ; Isocitrate Dehydrogenase/genetics

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Skocz do pozycji: 4.

Tytuł:: Helicobacter pylori and Epstein-Barr Virus Co-Infection in Gastric Disease: What Is the Correlation with p53 Mutation , Genes Methylation and Microsatellite Instability in a Cohort of Sicilian Population?
Autorzy:: Giammanco A; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Anzalone R; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Serra N; Department of Public Health, University Federico II of Naples, 80138 Napoli, Italy.
Graceffa G; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Vieni S; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Scibetta N; Anatomopathology Unit, Arnas Civico Di Cristina Benfratelli Hospital, 90127 Palermo, Italy.
Rea T; Public Health Department, Federico II University Hospital, 80131 Naples, Italy.
Capra G; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Fasciana T; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 30; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 30.
Typ publikacji:: Journal Article
MeSH Terms:: Helicobacter Infections*/complications
Epstein-Barr Virus Infections*/complications
Stomach Diseases*/genetics
Stomach Diseases*/microbiology
Stomach Diseases*/virology
Genes, p53*/genetics
DNA Methylation*
Microsatellite Instability*
Helicobacter pylori ; Herpesvirus 4, Human ; Coinfection ; Mutation ; Sicily ; Humans ; Male ; Female ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Logistic Models

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Skocz do pozycji: 5.

Tytuł:: Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice.
Autorzy:: Epstein RJ; University of New South Wales, St Vincent's Hospital Campus, Sydney, Australia.; Garvan Institute of Medical Research, Sydney, Australia.
Lin FPY; University of New South Wales, St Vincent's Hospital Campus, Sydney, Australia.; Centre for Clinical Genomics, The Kinghorn Cancer Centre, Sydney, Australia.
Brink RA; University of New South Wales, St Vincent's Hospital Campus, Sydney, Australia.; Garvan Institute of Medical Research, Sydney, Australia.
Blackburn J; University of New South Wales, St Vincent's Hospital Campus, Sydney, Australia.; Garvan Institute of Medical Research, Sydney, Australia.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Apr 13; Vol. 18 (4), pp. e0284327. Date of Electronic Publication: 2023 Apr 13 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Genes, p53*
Neoplasms*/genetics
Mice ; Humans ; Animals ; Mutation ; Methyl-CpG-Binding Protein 2/genetics ; RNA, Messenger ; CpG Islands ; DNA Methylation

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Skocz do pozycji: 6.

Tytuł:: Electrochemical detection of the p53 gene using exponential amplification reaction (EXPAR) and CRISPR/Cas12a reactions.
Autorzy:: Zhou S; Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, 400044, People's Republic of China.
Deng L; Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, 400044, People's Republic of China.
Dong J; Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, 400044, People's Republic of China.
Lu P; Chongqing University, Three Gorges Hospital, Chongqing, 404000, People's Republic of China.
Qi N; Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, 400044, People's Republic of China.
Huang Z; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, SeNA Research Institute and Szostak-CDHT Large Nucleic Acids Institute, Chengdu, 610065, People's Republic of China.
Yang M; Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, 400044, People's Republic of China.
Huo D; Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, 400044, People's Republic of China. .
Hou C; Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing, 400044, People's Republic of China. .; Chongqing Key Laboratory of Bio-Perception & Intelligent Information Processing, School of Microelectronics and Communication Engineering, Chongqing University, Chongqing, 400044, People's Republic of China. .; Pokaż więcej
Źródło:: Mikrochimica acta [Mikrochim Acta] 2023 Mar 04; Vol. 190 (4), pp. 113. Date of Electronic Publication: 2023 Mar 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CRISPR-Cas Systems*
Genes, p53*
Humans ; DNA Primers ; Electrodes ; Fluorescence

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Skocz do pozycji: 7.

Tytuł:: Target recognition assisted-primer exchange reaction (Ta-PER) for sensitive analysis of p53 gene and its application in analyzing amatoxin-treated samples.
Autorzy:: Zhao K; Fujian Provincial Center for Disease Control and Prevention, Fujian Academy of Preventive Medicine, Fuzhou City, 350012, Fujian Province, China. .
Fu W; Fujian Provincial Center for Disease Control and Prevention, Fujian Academy of Preventive Medicine, Fuzhou City, 350012, Fujian Province, China.
Huang Z; Fujian Provincial Center for Disease Control and Prevention, Fujian Academy of Preventive Medicine, Fuzhou City, 350012, Fujian Province, China.
Chen R; Fujian Provincial Center for Disease Control and Prevention, Fujian Academy of Preventive Medicine, Fuzhou City, 350012, Fujian Province, China.
Lin W; Fujian Provincial Center for Disease Control and Prevention, Fujian Academy of Preventive Medicine, Fuzhou City, 350012, Fujian Province, China.
Lin Z; Fujian Provincial Center for Disease Control and Prevention, Fujian Academy of Preventive Medicine, Fuzhou City, 350012, Fujian Province, China.; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2023 Jan; Vol. 415 (3), pp. 405-410. Date of Electronic Publication: 2022 Nov 12.
Typ publikacji:: Journal Article
MeSH Terms:: Genes, p53*
Biosensing Techniques*/methods
Humans ; HeLa Cells ; Nucleic Acid Amplification Techniques/methods

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Skocz do pozycji: 8.

Tytuł:: p53 oligomerization status as an indicator of sensitivity of p53-wildtype neuroblastomas to the combination of DNA damaging agent and Chk1 inhibitor.
Autorzy:: Levesque AA; Department of Biology, University of Hartford, West Hartford, Connecticut, United States of America.
Pappalardo RM; Department of Biology, University of Hartford, West Hartford, Connecticut, United States of America.
Puli P; Department of Biology, University of Hartford, West Hartford, Connecticut, United States of America.
Enzor LA; Department of Biology, University of Hartford, West Hartford, Connecticut, United States of America.
Angeles C; Department of Biology, University of Hartford, West Hartford, Connecticut, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Feb 10; Vol. 17 (2), pp. e0263463. Date of Electronic Publication: 2022 Feb 10 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Genes, p53*
Antineoplastic Agents/*pharmacology
Irinotecan/*pharmacology
Neuroblastoma/*drug therapy
Neuroblastoma/*genetics
Staurosporine/*analogs & derivatives
Topoisomerase I Inhibitors/*pharmacology
Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; DNA Damage ; DNA, Neoplasm/drug effects ; Humans ; Irinotecan/therapeutic use ; Staurosporine/pharmacology ; Staurosporine/therapeutic use ; Topoisomerase I Inhibitors/therapeutic use

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Skocz do pozycji: 9.

Tytuł:: Predicting clinical outcomes of cancer patients with a p53 deficiency gene signature.
Autorzy:: Schaafsma E; Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, NH, 03755, USA.
Takacs EM; Department of Biological Sciences, Kent State University, Kent, OH, 44242, USA.
Kaur S; Department of Biological Sciences, Kent State University, Kent, OH, 44242, USA.
Cheng C; Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, NH, 03755, USA. .; Department of Medicine, Baylor College of Medicine, Houston, TX, 77030, USA. .
Kurokawa M; Department of Biological Sciences, Kent State University, Kent, OH, 44242, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 25; Vol. 12 (1), pp. 1317. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genes, p53*
Mutation Rate*
Neoplasms/*genetics
Neoplasms/*mortality
Transcriptome/*genetics
Tumor Suppressor Protein p53/*deficiency
Tumor Suppressor Protein p53/*genetics
Drug Resistance, Neoplasm/genetics ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic ; Genomics/methods ; Humans ; Kaplan-Meier Estimate ; Neoplasms/metabolism ; Prognosis ; Survival Rate ; Tumor Microenvironment/genetics

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Skocz do pozycji: 10.

Tytuł:: Elevated serum expression of p53 and association of TP53 codon 72 polymorphisms with risk of cervical cancer in Bangladeshi women.
Autorzy:: Mostaid MS; Department of Pharmaceutical Sciences, School of Health and Life Sciences, North South University, Dhaka, Bangladesh.
Mumu SB; Department of Pharmaceutical Sciences, School of Health and Life Sciences, North South University, Dhaka, Bangladesh.
Haque MA; Department of Pharmacy, Brac University, Dhaka, Bangladesh.
Sharmin S; Department of Pharmacy, Brac University, Dhaka, Bangladesh.
Jamiruddin MR; Department of Pharmacy, Brac University, Dhaka, Bangladesh.
Sayedur Rahman GM; Department of Pharmaceutical Sciences, School of Health and Life Sciences, North South University, Dhaka, Bangladesh.
Reza HM; Department of Pharmaceutical Sciences, School of Health and Life Sciences, North South University, Dhaka, Bangladesh.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Dec 28; Vol. 16 (12), pp. e0261984. Date of Electronic Publication: 2021 Dec 28 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Genes, p53*
Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
Tumor Suppressor Protein p53/*blood
Uterine Cervical Neoplasms/*genetics
Adult ; Bangladesh/epidemiology ; Biopsy ; Case-Control Studies ; Codon ; Female ; Genotype ; Heterozygote ; Humans ; Linear Models ; Middle Aged ; Odds Ratio ; Quantitative Trait Loci ; Risk ; Risk Assessment ; Uterine Cervical Neoplasms/blood

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