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Tytuł :
Engineering multiple species-like genetic incompatibilities in insects.
Autorzy :
Maselko M; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Saint Paul, MN, USA.; Biotechnology Institute, University of Minnesota, Saint Paul, MN, USA.; Applied Biosciences, Macquarie University, North Ryde, NSW, Australia.
Feltman N; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Saint Paul, MN, USA.; Biotechnology Institute, University of Minnesota, Saint Paul, MN, USA.
Upadhyay A; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Saint Paul, MN, USA.; Biotechnology Institute, University of Minnesota, Saint Paul, MN, USA.; Department of Genetics, Cell Biology, and Development, University of Minnesota, Saint Paul, MN, 55108, USA.
Hayward A; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Saint Paul, MN, USA.; Biotechnology Institute, University of Minnesota, Saint Paul, MN, USA.
Das S; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Saint Paul, MN, USA.; Biotechnology Institute, University of Minnesota, Saint Paul, MN, USA.
Myslicki N; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Saint Paul, MN, USA.; Biotechnology Institute, University of Minnesota, Saint Paul, MN, USA.
Peterson AJ; Department of Genetics, Cell Biology, and Development, University of Minnesota, Saint Paul, MN, 55108, USA.
O'Connor MB; Department of Genetics, Cell Biology, and Development, University of Minnesota, Saint Paul, MN, 55108, USA.
Smanski MJ; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Saint Paul, MN, USA. .; Biotechnology Institute, University of Minnesota, Saint Paul, MN, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Sep 08; Vol. 11 (1), pp. 4468. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Genetic Speciation*
Drosophila melanogaster/*genetics
Genetic Engineering/*methods
Animals ; Animals, Genetically Modified ; Crosses, Genetic ; Female ; Genes, Insect ; Genes, Lethal ; Genotype ; Hybridization, Genetic ; Male ; Models, Genetic ; Transgenes
Czasopismo naukowe
Tytuł :
Detecting selection with a genetic cross.
Autorzy :
Fraser HB; Department of Biology, Stanford University, Stanford, CA 94305 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 08; Vol. 117 (36), pp. 22323-22330. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Crosses, Genetic*
Models, Genetic*
Selection, Genetic/*genetics
Animals ; Crops, Agricultural/genetics ; Drosophila/anatomy & histology ; Drosophila/genetics ; Evolution, Molecular ; Genetic Variation/genetics ; Humans ; Phenotype ; Quantitative Trait Loci/genetics ; Quantitative Trait, Heritable ; Saccharomyces cerevisiae/genetics ; Skin Pigmentation/genetics
Czasopismo naukowe
Tytuł :
Phylogenic analysis and forensic genetic characterization of Guizhou Miao tribes from 58 microareas via autosomal STR.
Autorzy :
Fan GY; Forensic Center, College of Medicine, Shaoxing University, Shaoxing 312000, China.
An YR; Criminal Technology Department, Liupanshui Public Security Bureau, Guizhou 553000, China.
Zhou YJ; College of Medicine, Shaoxing University, Shaoxing 312000, China.
Liu MN; College of Medicine, Shaoxing University, Shaoxing 312000, China.
Xiang J; GCP Center, West China Hospital of Sichuan University, Chengdu 610000, Sichuan, China.
Ye Y; West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu 610000, Sichuan, China. Electronic address: .
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Źródło :
Legal medicine (Tokyo, Japan) [Leg Med (Tokyo)] 2020 Nov; Vol. 47, pp. 101737. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Genetics, Population*
Phylogeny*
Polymorphism, Genetic*
Ethnic Groups/*genetics
Forensic Genetics/*methods
Genetic Variation/*genetics
Microsatellite Repeats/*genetics
China/ethnology ; Female ; Gene Frequency ; Genetic Loci/genetics ; Humans ; Male ; Principal Component Analysis
Czasopismo naukowe
Tytuł :
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.
Autorzy :
Surakka I; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Fritsche LG; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.
Zhou W; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA, 02142, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA.
Backman J; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Kosmicki JA; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Lu H; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Prinsesse Kristinas gate 3, 7030, Trondheim, Norway.
Nielsen JB; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.
Skogholt AH; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.
Wolford B; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA.
Graham SE; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Chen YE; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Lee S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.
Kang HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.
Langhammer A; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway.
Forsmo S; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway.
Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway.; Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Prinsesse Kristinas gate 3, 7030, Trondheim, Norway.
Styrkarsdottir U; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.
Holm H; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.
Gudbjartsson D; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Sturlugata 7, 101, Reykjavik, Iceland.
Stefansson K; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmýrarvegur 16, 101, Reykjavik, Iceland.
Baras A; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway. .; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway. .
Willer CJ; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA. .; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA. .; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway. .; Department of Human Genetics, University of Michigan, 4909 Buhl Building, 1241 E. Catherine St, Ann Arbor, MI, 48109, USA. .
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Corporate Authors :
Regeneron Genetics Center
Źródło :
Nature communications [Nat Commun] 2020 Oct 23; Vol. 11 (1), pp. 4093. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Association Studies*
Bone Density/*genetics
Extracellular Matrix Proteins/*genetics
Fractures, Bone/*genetics
Genetic Predisposition to Disease/*genetics
Glycoproteins/*genetics
Phosphoproteins/*genetics
Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Computational Biology ; Female ; Gene Frequency ; Genetic Testing ; Genome, Human ; Humans ; Iceland ; Male ; Middle Aged ; Osteoporosis/genetics
Czasopismo naukowe
Tytuł :
Changing local recombination patterns in Arabidopsis by CRISPR/Cas mediated chromosome engineering.
Autorzy :
Schmidt C; Botanical Institute, Karlsruhe Institute of Technology, Fritz-Haber-Weg 4, 76133, Karlsruhe, Germany.
Fransz P; Department of Plant Development and (Epi)Genetics, Swammerdam Institute of Life Sciences, University of Amsterdam, Postbus 1210, 1000 BE, Amsterdam, Netherlands.
Rönspies M; Botanical Institute, Karlsruhe Institute of Technology, Fritz-Haber-Weg 4, 76133, Karlsruhe, Germany.
Dreissig S; Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle Wittenberg, Karl-Freiherr-von-Fritsch-Str. 4, 06120, Halle, Germany.
Fuchs J; Leibniz Institute of Plant Genetics and Crop Plant Research, Corrensstraße 3, 06466, Gatersleben, Germany.
Heckmann S; Leibniz Institute of Plant Genetics and Crop Plant Research, Corrensstraße 3, 06466, Gatersleben, Germany.
Houben A; Leibniz Institute of Plant Genetics and Crop Plant Research, Corrensstraße 3, 06466, Gatersleben, Germany.
Puchta H; Botanical Institute, Karlsruhe Institute of Technology, Fritz-Haber-Weg 4, 76133, Karlsruhe, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 Sep 04; Vol. 11 (1), pp. 4418. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Chromosomes, Plant*
Recombination, Genetic*
Arabidopsis/*genetics
Genetic Engineering/*methods
CRISPR-Cas Systems ; Chromosome Inversion ; Crossing Over, Genetic ; Plant Breeding/methods ; Plants
Czasopismo naukowe
Tytuł :
Identification of the human DPR core promoter element using machine learning.
Autorzy :
Vo Ngoc L; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Huang CY; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Cassidy CJ; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Medrano C; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Kadonaga JT; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA. .
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Źródło :
Nature [Nature] 2020 Sep; Vol. 585 (7825), pp. 459-463. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Support Vector Machine*
Transcription, Genetic*
Consensus Sequence/*genetics
Gene Expression Regulation/*genetics
Promoter Regions, Genetic/*genetics
RNA Polymerase II/*metabolism
Base Sequence ; Cells/metabolism ; Computer Simulation ; Datasets as Topic ; HeLa Cells ; High-Throughput Nucleotide Sequencing ; Humans ; Models, Genetic ; Mutagenesis ; TATA Box/genetics
Czasopismo naukowe
Tytuł :
Natural selection versus creation: a review on the origin of SARS-COV-2.
Autorzy :
Barh D; Institute of Integrative Omics and Applied Biotechnology (IIOAB), Nonakuri, Purba Medinipur, WB, India.
Silva Andrade B; Laboratório de Bioinformática e Química Computacional, Departamento de Ciências Biológicas, Universidade Estadual do Sudoeste da Bahia (UESB), Jequié, Bahia, Brazil.
Tiwari S; Laboratório de Genética Celular e Molecular, Departamento de Genetica, Ecologia e Evolucao, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Giovanetti M; Laboratório de Genética Celular e Molecular, Departamento de Genetica, Ecologia e Evolucao, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Laboratório de Flavivírus, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Góes-Neto A; Laboratório de Biologia Molecular e Computacional de Fungos, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Alcantara LCJ; Laboratório de Genética Celular e Molecular, Departamento de Genetica, Ecologia e Evolucao, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Laboratório de Flavivírus, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Azevedo V; Laboratório de Genética Celular e Molecular, Departamento de Genetica, Ecologia e Evolucao, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Ghosh P; Department of Computer Science, Virginia Commonwealth University, Richmond, VA, 23284, USA.
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Źródło :
Le infezioni in medicina [Infez Med] 2020 Sep 01; Vol. 28 (3), pp. 302-311.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Selection, Genetic*
Betacoronavirus/*genetics
Coronavirus Infections/*virology
Genetic Engineering/*methods
Pneumonia, Viral/*virology
Animals ; Biohazard Release ; Biological Warfare Agents ; Chiroptera/virology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Dissent and Disputes ; Eutheria/classification ; Eutheria/virology ; Global Health/statistics & numerical data ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Recombination, Genetic ; Sequence Alignment ; Zoonoses/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Dynamic and scalable DNA-based information storage.
Autorzy :
Lin KN; Department of Chemical and Biomolecular Engineering, North Carolina State University, Campus Box 7905, Raleigh, NC, 27695-7905, USA.
Volkel K; Department of Electrical and Computer Engineering, North Carolina State University, Campus Box 7911, Raleigh, NC, 27695-7911, USA.
Tuck JM; Department of Electrical and Computer Engineering, North Carolina State University, Campus Box 7911, Raleigh, NC, 27695-7911, USA. .
Keung AJ; Department of Chemical and Biomolecular Engineering, North Carolina State University, Campus Box 7905, Raleigh, NC, 27695-7905, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 12; Vol. 11 (1), pp. 2981. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Regulation, Viral*
Genetic Code*
Bacteriophage T7/*genetics
DNA/*genetics
Promoter Regions, Genetic/*genetics
Algorithms ; DNA, Single-Stranded/genetics ; Models, Genetic ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
The delivery challenge: fulfilling the promise of therapeutic genome editing.
Autorzy :
van Haasteren J; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA, USA.
Li J; Department of Bioengineering, University of California, Berkeley, CA, USA.; Innovative Genomics Institute (IGI), University of California, Berkeley, CA, USA.
Scheideler OJ; Department of Bioengineering, University of California, Berkeley, CA, USA.
Murthy N; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA, USA. .; Department of Bioengineering, University of California, Berkeley, CA, USA. .; Innovative Genomics Institute (IGI), University of California, Berkeley, CA, USA. .
Schaffer DV; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA, USA. .; Department of Bioengineering, University of California, Berkeley, CA, USA. .; Innovative Genomics Institute (IGI), University of California, Berkeley, CA, USA. .; Department of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, USA. .; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. .; Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA. .
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Źródło :
Nature biotechnology [Nat Biotechnol] 2020 Jul; Vol. 38 (7), pp. 845-855. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Therapy*
CRISPR-Cas Systems/*genetics
Gene Editing/*trends
Genetic Diseases, Inborn/*therapy
Genetic Diseases, Inborn/genetics ; Genetic Vectors/genetics ; Genetic Vectors/therapeutic use ; Humans ; Nanoparticles/therapeutic use ; Protein Engineering
Czasopismo naukowe
Tytuł :
Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites.
Autorzy :
Promonet A; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France.
Padioleau I; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France.; Institut Gustave Roussy, Villejuif, France.
Liu Y; Institut Curie, PSL Research University, CNRS, UMR3244, Sorbonne Université, Paris, France.
Sanz L; Department of Molecular and Cellular Biology, University of California, Davis, CA, 95616, USA.
Biernacka A; Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Warsaw, Poland.
Schmitz AL; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France.
Skrzypczak M; Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Warsaw, Poland.
Sarrazin A; BioCampus Montpellier, CNRS et Université de Montpellier, Montpellier, France.
Mettling C; Institut de Génétique Humaine, CNRS et Université de Montpellier, Montpellier, France.
Rowicka M; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Ginalski K; Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Warsaw, Poland.
Chedin F; Department of Molecular and Cellular Biology, University of California, Davis, CA, 95616, USA.
Chen CL; Institut Curie, PSL Research University, CNRS, UMR3244, Sorbonne Université, Paris, France. .
Lin YL; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France. .
Pasero P; Institut de Génétique Humaine, CNRS et Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France. .
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Źródło :
Nature communications [Nat Commun] 2020 Aug 07; Vol. 11 (1), pp. 3940. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Replication*
Transcription, Genetic*
DNA Topoisomerases, Type I/*metabolism
R-Loop Structures/*genetics
Terminator Regions, Genetic/*genetics
Ataxia Telangiectasia Mutated Proteins/metabolism ; DNA Breaks, Double-Stranded ; DNA Topoisomerases, Type I/genetics ; Gene Knockdown Techniques ; Genomic Instability ; HEK293 Cells ; HeLa Cells ; Humans ; Phosphorylation ; Promoter Regions, Genetic ; RNA, Small Interfering/metabolism
Czasopismo naukowe
Tytuł :
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency.
Autorzy :
Kang MH; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
van Lieshout LP; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Xu L; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Domm JM; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Vadivel A; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Renesme L; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Mühlfeld C; Institute of Functional and Applied Anatomy, Hannover Medical School, 30625, Hannover, Germany.
Hurskainen M; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Mižíková I; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Pei Y; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
van Vloten JP; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Thomas SP; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Milazzo C; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Cyr-Depauw C; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Whitsett JA; Divisions of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA.
Nogee LM; Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Wootton SK; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada. .
Thébaud B; Sinclair Center for Regenerative Medicine, Ottawa Hospital Research Institute, Ottawa, ON, K1Y 4E9, Canada. .; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada. .; Neonatology, Department of Pediatrics, Children's Hospital of Eastern Ontario (CHEO) and CHEO Research Institute, Ottawa, ON, K1H 8L1, Canada. .
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Źródło :
Nature communications [Nat Commun] 2020 Aug 06; Vol. 11 (1), pp. 3929. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Vectors*
Genetic Therapy/*methods
Parvovirinae/*genetics
Pulmonary Alveolar Proteinosis/*congenital
Pulmonary Surfactant-Associated Protein B/*deficiency
Animals ; Animals, Newborn ; Cell Line ; Disease Models, Animal ; Female ; Gene Expression ; HEK293 Cells ; Humans ; Lung/metabolism ; Lung/pathology ; Male ; Mice ; Mice, Transgenic ; Protein Precursors/genetics ; Proteolipids/genetics ; Pulmonary Alveolar Proteinosis/genetics ; Pulmonary Alveolar Proteinosis/metabolism ; Pulmonary Alveolar Proteinosis/therapy ; Pulmonary Surfactant-Associated Protein B/genetics ; Pulmonary Surfactant-Associated Protein B/metabolism ; Pulmonary Surfactant-Associated Proteins/genetics ; Transduction, Genetic
SCR Disease Name :
Congenital Deficiency of Pulmonary Surfactant Protein B
Czasopismo naukowe
Tytuł :
Regulatory sharing between estrogen receptor α bound enhancers.
Autorzy :
Carleton JB; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.
Ginley-Hidinger M; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, USA.
Berrett KC; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.
Layer RM; BioFrontiers Institute, University of Colorado, Boulder, CO, USA.; Department of Computer Science, University of Colorado, Boulder, CO, USA.
Quinlan AR; Departments of Human Genetics and Biomedical Informatics, University of Utah, Salt Lake City, UT, USA.
Gertz J; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jul 09; Vol. 48 (12), pp. 6597-6610.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription, Genetic*
Enhancer Elements, Genetic/*genetics
Estrogen Receptor alpha/*genetics
Nucleotide Motifs/*genetics
Acetylation ; Chromatin/genetics ; DNA-Binding Proteins/genetics ; Gene Expression Regulation/genetics ; Genome, Human/genetics ; Humans ; Promoter Regions, Genetic/genetics
Czasopismo naukowe
Tytuł :
Natural variations at the Stay-Green gene promoter control lifespan and yield in rice cultivars.
Autorzy :
Shin D; Department of Southern Area Crop Science, National Institute of Crop Science (NICS), RDA, Miryang, Republic of Korea.
Lee S; Center for Plant Aging Research, Institute for Basic Science (IBS), Daegu, Republic of Korea. .
Kim TH; Department of Southern Area Crop Science, National Institute of Crop Science (NICS), RDA, Miryang, Republic of Korea.
Lee JH; Department of Southern Area Crop Science, National Institute of Crop Science (NICS), RDA, Miryang, Republic of Korea.
Park J; Center for Plant Aging Research, Institute for Basic Science (IBS), Daegu, Republic of Korea.
Lee J; Center for Plant Aging Research, Institute for Basic Science (IBS), Daegu, Republic of Korea.
Lee JY; Department of Southern Area Crop Science, National Institute of Crop Science (NICS), RDA, Miryang, Republic of Korea.
Cho LH; Crop Biotech Institute and Graduate School of Biotechnology, Kyung Hee University, Yongin, Republic of Korea.
Choi JY; Center for Genomics and Systems Biology, Department of Biology, New York University, New York, NY, USA.
Lee W; Department of New Biology, DGIST, Daegu, Republic of Korea.
Park JH; Center for Plant Aging Research, Institute for Basic Science (IBS), Daegu, Republic of Korea.
Lee DW; Crop Biotech Institute and Graduate School of Biotechnology, Kyung Hee University, Yongin, Republic of Korea.
Ito H; Institute of Low Temperature Science, Hokkaido University, Sapporo, Japan.
Kim DH; Department of Biology, Sunchon National University, Sunchon, Republic of Korea.
Tanaka A; Institute of Low Temperature Science, Hokkaido University, Sapporo, Japan.
Cho JH; Department of Southern Area Crop Science, National Institute of Crop Science (NICS), RDA, Miryang, Republic of Korea.
Song YC; Department of Southern Area Crop Science, National Institute of Crop Science (NICS), RDA, Miryang, Republic of Korea.
Hwang D; Center for Plant Aging Research, Institute for Basic Science (IBS), Daegu, Republic of Korea.; Department of New Biology, DGIST, Daegu, Republic of Korea.
Purugganan MD; Center for Genomics and Systems Biology, Department of Biology, New York University, New York, NY, USA.
Jeon JS; Crop Biotech Institute and Graduate School of Biotechnology, Kyung Hee University, Yongin, Republic of Korea.
An G; Crop Biotech Institute and Graduate School of Biotechnology, Kyung Hee University, Yongin, Republic of Korea.
Nam HG; Center for Plant Aging Research, Institute for Basic Science (IBS), Daegu, Republic of Korea. .; Department of New Biology, DGIST, Daegu, Republic of Korea. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 04; Vol. 11 (1), pp. 2819. Date of Electronic Publication: 2020 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, Plant*
Genetic Variation*
Oryza/*genetics
Oryza/*growth & development
Promoter Regions, Genetic/*genetics
Alleles ; Base Sequence ; Gene Expression Regulation, Plant ; Inbreeding ; Phenotype ; Polymorphism, Genetic ; Quantitative Trait Loci/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
WY7 is a newly identified promoter from the rubber powdery mildew pathogen that regulates exogenous gene expression in both monocots and dicots.
Autorzy :
Wang Y; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Hainan University, Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Wang C; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Hainan University, Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Rajaofera MJN; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Hainan University, Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Zhu L; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Hainan University, Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Liu W; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Hainan University, Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Zheng F; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Hainan University, Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
Miao W; Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Hainan University, Ministry of Education, Haikou, China.; College of Plant Protection, Hainan University, Haikou, China.
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Źródło :
PloS one [PLoS One] 2020 Jun 01; Vol. 15 (6), pp. e0233911. Date of Electronic Publication: 2020 Jun 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Fungal*
Promoter Regions, Genetic*
Fungi/*genetics
Genetic Engineering/*methods
Plant Diseases/*prevention & control
Fungi/pathogenicity ; Genome, Fungal ; Hevea/genetics ; Hevea/microbiology ; Host-Pathogen Interactions/genetics ; Magnoliopsida/genetics ; Magnoliopsida/microbiology ; Oryza/genetics ; Oryza/microbiology ; Plant Diseases/microbiology ; Plant Leaves/microbiology ; Plants, Genetically Modified ; Tobacco/genetics ; Tobacco/microbiology ; Transformation, Genetic ; Zea mays/genetics ; Zea mays/microbiology
Czasopismo naukowe
Tytuł :
Genetic Variants and Haplotypes in OPG Gene Are Associated with Premature Coronary Artery Disease and Traditional Cardiovascular Risk Factors in Mexican Population: The GEA Study.
Autorzy :
Pérez-Hernández N; Department of Molecular Biology and Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Posadas-Sánchez R; Department of Endocrinology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Vargas-Alarcón G; Department of Molecular Biology and Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Cazarín-Santos BG; Department of Molecular Biology and Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Miranda-Duarte A; Department of Genetics, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City, Mexico.
Rodríguez-Pérez JM; Department of Molecular Biology and Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2020 Nov; Vol. 39 (11), pp. 2085-2094. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Association Studies*
Genetic Predisposition to Disease*
Coronary Artery Disease/*genetics
Osteoprotegerin/*genetics
Aged ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/genetics ; Cardiovascular Diseases/pathology ; Coronary Artery Disease/epidemiology ; Coronary Artery Disease/pathology ; Female ; Genetic Variation/genetics ; Genotype ; Haplotypes ; Humans ; Male ; Mexico/epidemiology ; Middle Aged ; Polymorphism, Single Nucleotide/genetics ; Risk Factors
Czasopismo naukowe
Tytuł :
Combined Utility of 25 Disease and Risk Factor Polygenic Risk Scores for Stratifying Risk of All-Cause Mortality.
Autorzy :
Meisner A; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Kundu P; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Zhang YD; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA; Department of Statistics, University of Hong Kong, 999077, Hong Kong.
Lan LV; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Kim S; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Ghandwani D; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA; Indian Statistical Institute, Kolkata, West Bengal 700108, India.
Pal Choudhury P; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA.
Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA.
Freedman ND; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA.
Garcia-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA.
Chatterjee N; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: .
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Źródło :
American journal of human genetics [Am J Hum Genet] 2020 Sep 03; Vol. 107 (3), pp. 418-431. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Genetic Diseases, Inborn/*mortality
Multifactorial Inheritance/*genetics
Risk Assessment/*statistics & numerical data
Biological Specimen Banks ; Female ; Genetic Diseases, Inborn/genetics ; Genetic Diseases, Inborn/pathology ; Genome-Wide Association Study ; Humans ; Male ; Middle Aged ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Proportional Hazards Models ; Risk Factors ; United Kingdom
Czasopismo naukowe
Tytuł :
Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts.
Autorzy :
Yoo JI; Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA.
Seppälä S; Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA.
OʼMalley MA; Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 29; Vol. 11 (1), pp. 5459. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Fluorides*/metabolism
Fluorides*/pharmacology
Selection, Genetic*
Membrane Proteins/*genetics
Organisms, Genetically Modified/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Genetic Engineering ; Genetic Markers ; Saccharomyces cerevisiae/drug effects ; Synthetic Biology/methods
Czasopismo naukowe
Tytuł :
Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants.
Autorzy :
Weinmann J; Heidelberg University Hospital, Dept. of Infectious Diseases/Virology, Cluster of Excellence CellNetworks, 69120, Heidelberg, Germany.; BioQuant, University of Heidelberg, 69120, Heidelberg, Germany.
Weis S; Heidelberg University Hospital, Dept. of Infectious Diseases/Virology, Cluster of Excellence CellNetworks, 69120, Heidelberg, Germany.; BioQuant, University of Heidelberg, 69120, Heidelberg, Germany.
Sippel J; Heidelberg University Hospital, Dept. of Infectious Diseases/Virology, Cluster of Excellence CellNetworks, 69120, Heidelberg, Germany.; BioQuant, University of Heidelberg, 69120, Heidelberg, Germany.
Tulalamba W; Vrije Universiteit Brussel, Department of Gene Therapy & Regenerative Medicine, 1090, Brussels, Belgium.
Remes A; University Hospital Schleswig-Holstein, Campus Kiel, Innere Medizin III, 24105, Kiel, Germany.; German Center for Infection Research (DZIF) and German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany.
El Andari J; Heidelberg University Hospital, Dept. of Infectious Diseases/Virology, Cluster of Excellence CellNetworks, 69120, Heidelberg, Germany.; BioQuant, University of Heidelberg, 69120, Heidelberg, Germany.
Herrmann AK; Heidelberg University Hospital, Dept. of Infectious Diseases/Virology, Cluster of Excellence CellNetworks, 69120, Heidelberg, Germany.; BioQuant, University of Heidelberg, 69120, Heidelberg, Germany.
Pham QH; Vrije Universiteit Brussel, Department of Gene Therapy & Regenerative Medicine, 1090, Brussels, Belgium.
Borowski C; University Hospital Schleswig-Holstein, Campus Kiel, Innere Medizin III, 24105, Kiel, Germany.; German Center for Infection Research (DZIF) and German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany.
Hille S; University Hospital Schleswig-Holstein, Campus Kiel, Innere Medizin III, 24105, Kiel, Germany.; German Center for Infection Research (DZIF) and German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany.
Schönberger T; Boehringer Ingelheim Pharma GmbH & Co. KG, Drug Discovery Sciences, 88400, Biberach an der Riß, Germany.
Frey N; University Hospital Schleswig-Holstein, Campus Kiel, Innere Medizin III, 24105, Kiel, Germany.; German Center for Infection Research (DZIF) and German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany.
Lenter M; Boehringer Ingelheim Pharma GmbH & Co. KG, Drug Discovery Sciences, 88400, Biberach an der Riß, Germany.
VandenDriessche T; Vrije Universiteit Brussel, Department of Gene Therapy & Regenerative Medicine, 1090, Brussels, Belgium.; University of Leuven, Center for Molecular & Vascular Biology, Department of Cardiovascular Sciences, Leuven, 3000, Belgium.
Müller OJ; University Hospital Schleswig-Holstein, Campus Kiel, Innere Medizin III, 24105, Kiel, Germany.; German Center for Infection Research (DZIF) and German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, 24105, Kiel, Germany.
Chuah MK; Vrije Universiteit Brussel, Department of Gene Therapy & Regenerative Medicine, 1090, Brussels, Belgium.; University of Leuven, Center for Molecular & Vascular Biology, Department of Cardiovascular Sciences, Leuven, 3000, Belgium.
Lamla T; Boehringer Ingelheim Pharma GmbH & Co. KG, Drug Discovery Sciences, 88400, Biberach an der Riß, Germany.
Grimm D; Heidelberg University Hospital, Dept. of Infectious Diseases/Virology, Cluster of Excellence CellNetworks, 69120, Heidelberg, Germany. .; BioQuant, University of Heidelberg, 69120, Heidelberg, Germany. .; German Center for Infection Research (DZIF) and German Center for Cardiovascular Research (DZHK), partner site Heidelberg, 69120, Heidelberg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 28; Vol. 11 (1), pp. 5432. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Genetic Vectors*
Capsid Proteins/*genetics
Dependovirus/*genetics
Muscles/*metabolism
Muscles/*virology
Animals ; Capsid ; DNA Barcoding, Taxonomic ; Female ; Gene Library ; Genetic Therapy/methods ; Genetic Variation ; High-Throughput Nucleotide Sequencing ; Humans ; Mice ; Mice, Inbred C57BL ; Mutation ; Organ Specificity
Czasopismo naukowe
Tytuł :
Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination.
Autorzy :
Huang KL; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA.
Jee D; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Stein CB; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Elrod ND; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA.
Henriques T; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Mascibroda LG; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA.
Baillat D; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA.
Russell WK; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA.
Adelman K; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: .
Wagner EJ; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Oct 15; Vol. 80 (2), pp. 345-358.e9. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Transcription Termination, Genetic*
Drosophila Proteins/*metabolism
Protein Phosphatase 2/*metabolism
Protein Subunits/*metabolism
Amino Acid Motifs ; Amino Acid Sequence ; Animals ; Conserved Sequence ; Drosophila Proteins/chemistry ; Drosophila melanogaster ; Gene Expression Regulation ; Genetic Loci ; Humans ; Phosphorylation ; Promoter Regions, Genetic ; Protein Subunits/chemistry ; RNA Polymerase II/chemistry ; RNA Polymerase II/metabolism ; Signal Transduction ; Substrate Specificity
Czasopismo naukowe
Tytuł :
DGINN, an automated and highly-flexible pipeline for the detection of genetic innovations on protein-coding genes.
Autorzy :
Picard L; CIRI - Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.; Laboratoire de Biologie et Biométrie Evolutive, CNRS UMR 5558, Université Claude Bernard Lyon 1, Villeurbanne, France.
Ganivet Q; Laboratoire de Biologie et Biométrie Evolutive, CNRS UMR 5558, Université Claude Bernard Lyon 1, Villeurbanne, France.
Allatif O; CIRI - Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.
Cimarelli A; CIRI - Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.
Guéguen L; Laboratoire de Biologie et Biométrie Evolutive, CNRS UMR 5558, Université Claude Bernard Lyon 1, Villeurbanne, France.; Swedish Collegium for Advanced Study, Uppsala, Sweden.
Etienne L; CIRI - Centre International de Recherche en Infectiologie, Univ Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Oct 09; Vol. 48 (18), pp. e103.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Databases, Genetic*
Primates/*genetics
Proteins/*genetics
Animals ; Evolution, Molecular ; Genetic Variation ; Selection, Genetic
Czasopismo naukowe

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