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Wyszukujesz frazę ""Genetic Association Studies"" wg kryterium: Temat


Tytuł :
Associations Between Genetically Predicted Protein Levels and COVID-19 Severity.
Autorzy :
Zhu J; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Wu C; Department of Statistics, Florida State University, Tallahassee, Florida, USA.
Wu L; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2021 Jan 04; Vol. 223 (1), pp. 19-22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Association Studies*
Blood Proteins/*analysis
COVID-19/*diagnosis
COVID-19/*genetics
Case-Control Studies ; Humans ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Activating somatic and germline TERT promoter variants in myeloid malignancies.
Autorzy :
Nofrini V; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Matteucci C; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Pellanera F; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Gorello P; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Di Giacomo D; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Lema Fernandez AG; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Nardelli C; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Iannotti T; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Brandimarte L; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Arniani S; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Moretti M; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Gili A; Public Health Section, Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Roti G; Hematology and Bone Marrow Transplantation Unit, University of Parma, Parma, Italy.
Di Battista V; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy.
Colla S; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Mecucci C; University of Perugia, Section of Hematology and Center for Hemato-Oncology Research (C.R.E.O.), Perugia, Italy. .
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Źródło :
Leukemia [Leukemia] 2021 Jan; Vol. 35 (1), pp. 274-278. Date of Electronic Publication: 2020 May 04.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Association Studies*/methods
Genetic Predisposition to Disease*
Germ-Line Mutation*
Mutation*
Promoter Regions, Genetic*
Leukemia, Myeloid/*genetics
Telomerase/*genetics
Alleles ; Genotype ; Humans ; Leukemia, Myeloid/diagnosis
Raport
Tytuł :
Pituitary stalk interruption syndrome is characterized by genetic heterogeneity.
Autorzy :
Brauner R; Fondation Ophtalmologique Adolphe de Rothschild and Université Paris Descartes, Paris, France.
Bignon-Topalovic J; Human Developmental Genetics Unit, Institute Pasteur, Paris, France.
Bashamboo A; Human Developmental Genetics Unit, Institute Pasteur, Paris, France.
McElreavey K; Human Developmental Genetics Unit, Institute Pasteur, Paris, France.
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Źródło :
PloS one [PLoS One] 2020 Dec 03; Vol. 15 (12), pp. e0242358. Date of Electronic Publication: 2020 Dec 03 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Association Studies*
Genetic Predisposition to Disease*
Nerve Tissue Proteins/*genetics
Pituitary Diseases/*genetics
Child ; Child, Preschool ; Dwarfism/epidemiology ; Dwarfism/genetics ; Dwarfism/pathology ; Female ; Genetic Heterogeneity ; Humans ; Infant ; Infant, Newborn ; Male ; Mutation/genetics ; Pituitary Diseases/epidemiology ; Pituitary Diseases/pathology ; Pituitary Gland/metabolism ; Pituitary Gland/pathology
Czasopismo naukowe
Tytuł :
Aberrant splicing due to a novel RPS7 variant causes Diamond-Blackfan Anemia associated with spontaneous remission and meningocele.
Autorzy :
Akram T; Human Molecular Genetics Laboratory, National Institute for Biotechnology and Genetic Engineering (NIBGE-C)-PIEAS, Faisalabad, Pakistan.; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, BMC Box 815, Uppsala, Sweden.
Fatima A; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, BMC Box 815, Uppsala, Sweden.
Klar J; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, BMC Box 815, Uppsala, Sweden.
Hoeber J; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, BMC Box 815, Uppsala, Sweden.
Zakaria M; Center for Human Genetics, Hazara University, Mansehra, Pakistan.
Tariq M; Human Molecular Genetics Laboratory, National Institute for Biotechnology and Genetic Engineering (NIBGE-C)-PIEAS, Faisalabad, Pakistan.
Baig SM; Human Molecular Genetics Laboratory, National Institute for Biotechnology and Genetic Engineering (NIBGE-C)-PIEAS, Faisalabad, Pakistan.
Schuster J; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, BMC Box 815, Uppsala, Sweden.
Dahl N; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, BMC Box 815, Uppsala, Sweden. .
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Źródło :
International journal of hematology [Int J Hematol] 2020 Dec; Vol. 112 (6), pp. 894-899. Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Chromosome Aberrations*
Genetic Association Studies*
Anemia, Diamond-Blackfan/*genetics
Genetic Variation/*genetics
Meningocele/*genetics
RNA Splicing/*genetics
Ribosomal Proteins/*genetics
Adolescent ; Adult ; Anemia, Diamond-Blackfan/etiology ; Child ; Exons/genetics ; Female ; Humans ; Meningocele/etiology ; Mother-Child Relations ; Remission, Spontaneous ; Sequence Analysis, DNA
Czasopismo naukowe
Tytuł :
Population Difference in Allele Frequency of HLA-C*05 and Its Correlation with COVID-19 Mortality.
Autorzy :
Sakuraba A; Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago Medicine, Chicago, IL 60637, USA.
Haider H; Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago Medicine, Chicago, IL 60637, USA.
Sato T; Department of Organoid Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan.; Corona Virus Task Force, Keio University School of Medicine, Tokyo 160-8582, Japan.
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Źródło :
Viruses [Viruses] 2020 Nov 20; Vol. 12 (11). Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Frequency*
Genetic Association Studies*
COVID-19/*genetics
COVID-19/*mortality
HLA-C Antigens/*genetics
Databases, Nucleic Acid ; Global Health ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Humans ; Immunity, Innate ; Multivariate Analysis ; Pandemics ; Receptors, KIR/genetics ; Risk Factors ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Genetic Variants and Haplotypes in OPG Gene Are Associated with Premature Coronary Artery Disease and Traditional Cardiovascular Risk Factors in Mexican Population: The GEA Study.
Autorzy :
Pérez-Hernández N; Department of Molecular Biology and Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Posadas-Sánchez R; Department of Endocrinology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Vargas-Alarcón G; Department of Molecular Biology and Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Cazarín-Santos BG; Department of Molecular Biology and Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Miranda-Duarte A; Department of Genetics, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City, Mexico.
Rodríguez-Pérez JM; Department of Molecular Biology and Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2020 Nov; Vol. 39 (11), pp. 2085-2094. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Association Studies*
Genetic Predisposition to Disease*
Coronary Artery Disease/*genetics
Osteoprotegerin/*genetics
Aged ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/genetics ; Cardiovascular Diseases/pathology ; Coronary Artery Disease/epidemiology ; Coronary Artery Disease/pathology ; Female ; Genetic Variation/genetics ; Genotype ; Haplotypes ; Humans ; Male ; Mexico/epidemiology ; Middle Aged ; Polymorphism, Single Nucleotide/genetics ; Risk Factors
Czasopismo naukowe
Tytuł :
Association of MDM2 T309G (rs2279744) Polymorphism and Expression Changes With Risk of Prostate Cancer in the Slovak Population.
Autorzy :
Sivonova MK; Department of Medical Biochemistry, Comenius University in Bratislava, Jessenius Faculty of Medicine, Martin, Slovak Republic .
Jurecekova J; Department of Medical Biochemistry, Comenius University in Bratislava, Jessenius Faculty of Medicine, Martin, Slovak Republic.
Kaplan P; Department of Medical Biochemistry, Comenius University in Bratislava, Jessenius Faculty of Medicine, Martin, Slovak Republic.
Hives M; Department of Medical Biochemistry, Comenius University in Bratislava, Jessenius Faculty of Medicine, Martin, Slovak Republic.
Grendar M; Biomedical Center Martin, Comenius University in Bratislava, Jessenius Faculty of Medicine, Martin, Slovak Republic.
Tomascova A; Biomedical Center Martin, Comenius University in Bratislava, Jessenius Faculty of Medicine, Martin, Slovak Republic.
Dusenka R; Department of Urology, Comenius University in Bratislava, Jessenius Faculty of Medicine and UHM, Martin, Slovak Republic.
Drobkova H; Biomedical Center Martin, Comenius University in Bratislava, Jessenius Faculty of Medicine, Martin, Slovak Republic.
Evin D; Department of Medical Biochemistry, Comenius University in Bratislava, Jessenius Faculty of Medicine, Martin, Slovak Republic.; Department of Nuclear Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine and UHM, Martin, Slovak Republic.
Kliment J; Department of Urology, Comenius University in Bratislava, Jessenius Faculty of Medicine and UHM, Martin, Slovak Republic.
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Źródło :
Anticancer research [Anticancer Res] 2020 Nov; Vol. 40 (11), pp. 6257-6264.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Genetic Association Studies*
Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide/*genetics
Prostatic Neoplasms/*genetics
Proto-Oncogene Proteins c-mdm2/*genetics
Aged ; Case-Control Studies ; Gene Frequency ; Humans ; Male ; Prostatic Neoplasms/pathology ; Risk Factors ; Slovakia
Czasopismo naukowe
Tytuł :
A lead candidate functional single nucleotide polymorphism within the WARS2 gene associated with waist-hip-ratio does not alter RNA stability.
Autorzy :
Mušo M; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire OX11 0RD, UK.
Dumbell R; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire OX11 0RD, UK.
Pulit S; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands; Big Data Institute, Li Ka Shing Center for Health Information and Discovery, Oxford University, Oxford, UK; Program in Medical Population Genetics, Broad Institute, Cambridge, MA, USA.
Sinnott-Armstrong N; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Laber S; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire OX11 0RD, UK.
Zolkiewski L; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire OX11 0RD, UK.
Bentley L; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire OX11 0RD, UK.
Claussnitzer M; The Broad Institute of MIT and Harvard, Cambridge, MA, USA; Gerontology Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Institute of Nutritional Science, University of Hohenheim, Stuttgart, Germany.
Cox RD; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire OX11 0RD, UK. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2020 Nov; Vol. 1863 (11), pp. 194640. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Association Studies*
Polymorphism, Single Nucleotide*
Quantitative Trait, Heritable*
T-Box Domain Proteins/*genetics
3' Untranslated Regions ; Adipocytes, White/metabolism ; Alleles ; Cell Line, Tumor ; Computational Biology/methods ; Genes, Reporter ; Heterozygote ; Humans ; Nucleic Acid Conformation ; Quantitative Trait Loci ; RNA Stability ; Waist-Hip Ratio
Czasopismo naukowe
Tytuł :
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.
Autorzy :
Surakka I; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Fritsche LG; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.
Zhou W; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA, 02142, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA.
Backman J; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Kosmicki JA; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Lu H; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Prinsesse Kristinas gate 3, 7030, Trondheim, Norway.
Nielsen JB; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.
Skogholt AH; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.
Wolford B; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA.
Graham SE; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Chen YE; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Lee S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.
Kang HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.
Langhammer A; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway.
Forsmo S; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway.
Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway.; Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Prinsesse Kristinas gate 3, 7030, Trondheim, Norway.
Styrkarsdottir U; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.
Holm H; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.
Gudbjartsson D; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Sturlugata 7, 101, Reykjavik, Iceland.
Stefansson K; deCODE genetics/Amgen, Inc., Sturlugata 8, 101, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmýrarvegur 16, 101, Reykjavik, Iceland.
Baras A; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, 1415 Washington Heights, 1700 SPH I, Ann Arbor, MI, 48109, USA.; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway. .; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Postboks 8905, N-7491, Levanger, Norway. .
Willer CJ; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA. .; Department of Computational Medicine and Bioinformatics, University of Michigan, Palmer Commons, 100 Washtenaw Avenue, Ann Arbor, MI, 48109, USA. .; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway. .; Department of Human Genetics, University of Michigan, 4909 Buhl Building, 1241 E. Catherine St, Ann Arbor, MI, 48109, USA. .
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Corporate Authors :
Regeneron Genetics Center
Źródło :
Nature communications [Nat Commun] 2020 Oct 23; Vol. 11 (1), pp. 4093. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Association Studies*
Bone Density/*genetics
Extracellular Matrix Proteins/*genetics
Fractures, Bone/*genetics
Genetic Predisposition to Disease/*genetics
Glycoproteins/*genetics
Phosphoproteins/*genetics
Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Computational Biology ; Female ; Gene Frequency ; Genetic Testing ; Genome, Human ; Humans ; Iceland ; Male ; Middle Aged ; Osteoporosis/genetics
Czasopismo naukowe
Tytuł :
Genotype-phenotype correlation of HbH disease in northern Iraq.
Autorzy :
Shamoon RP; Department of Pathology, College of Medicine, Hawler Medical University, Erbil, Iraq. .; Lab. Section, Thalassemia Care Center, Erbil, Iraq. .
Yassin AK; Department of Internal Medicine, College of Medicine, Hawler Medical University, Erbil, Iraq.; Department of Clinical Hematology, Nanakali Hemato-Oncology Teaching Center, Erbil, Iraq.
Polus RK; Department of Pathology, College of Medicine, Hawler Medical University, Erbil, Iraq.
Ali MD; Department of Clinical Hematology, Nanakali Hemato-Oncology Teaching Center, Erbil, Iraq.
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Źródło :
BMC medical genetics [BMC Med Genet] 2020 Oct 15; Vol. 21 (1), pp. 203. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Genetic Association Studies/*methods
Hemoglobin H/*genetics
alpha-Globins/*genetics
alpha-Thalassemia/*genetics
Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Female ; Genetic Association Studies/statistics & numerical data ; Genotype ; Humans ; Infant ; Iraq ; Male ; Middle Aged ; Phenotype ; Young Adult ; alpha-Thalassemia/diagnosis
Czasopismo naukowe
Tytuł :
Contribution of Matrix Metalloproteinase-9 rs3918242 Genotypes to Childhood Leukemia Risk.
Autorzy :
Kuo CC; Department of Pediatric Orthopedics, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Tsai CW; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Chang WS; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Shen TC; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Tzeng HE; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan, R.O.C.; Division of Hematology and Oncology, Department of Medicine, Taipei Medical University Hospital, Taipei, Taiwan, R.O.C.; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan, R.O.C.
Li CH; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Wang YC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Tsai FJ; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Bau DT; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C. .; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan, R.O.C.
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Źródło :
Anticancer research [Anticancer Res] 2020 Oct; Vol. 40 (10), pp. 5751-5756.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Association Studies*
Genetic Predisposition to Disease*
Matrix Metalloproteinase 9/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Adult ; Alleles ; Child ; Female ; Genotype ; Heterozygote ; Humans ; Male ; Polymorphism, Single Nucleotide/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Promoter Regions, Genetic/genetics
Czasopismo naukowe
Tytuł :
Genetic associations of single nucleotide polymorphisms in the l-DOPA receptor (GPR143) gene with severity of nicotine dependence in Japanese individuals, and attenuation of nicotine reinforcement in Gpr143 gene-deficient mice.
Autorzy :
Masukawa D; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Nishizawa D; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.
Kanai K; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Kitamura S; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Kasahara Y; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Hashimoto T; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Takahagi R; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Hasegawa J; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.
Nakayama K; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.
Sato N; Department of Clinical Nursing, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka, 431-3192, Japan; Department of Tumor Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Tanioka F; Department of Pathology, Iwata City Hospital, 512-3 Okubo, Iwata, Shizuoka, 438-8550, Japan.
Sugimura H; Department of Tumor Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Ikeda K; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.
Goshima Y; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan. Electronic address: .
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Oct; Vol. 144 (2), pp. 89-93. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Deletion*
Genetic Association Studies*
Polymorphism, Single Nucleotide*
Reinforcement, Psychology*
Eye Proteins/*genetics
Membrane Glycoproteins/*genetics
Nicotine/*adverse effects
Receptors, G-Protein-Coupled/*genetics
Receptors, Neurotransmitter/*genetics
Substance-Related Disorders/*genetics
Animals ; Asian Continental Ancestry Group ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
PNPLA3 gene polymorphism and overall and cardiovascular mortality in the United States.
Autorzy :
Wijarnpreecha K; Department of Internal Medicine, Bassett Medical Center, Cooperstown, New York, USA.; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Scribani M; Bassett Research Institute, Bassett Medical Center, Cooperstown, New York, USA.
Raymond P; Department of Internal Medicine, Bassett Medical Center, Cooperstown, New York, USA.
Harnois DM; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Keaveny AP; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Ahmed A; Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA.
Kim D; Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA.
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Źródło :
Journal of gastroenterology and hepatology [J Gastroenterol Hepatol] 2020 Oct; Vol. 35 (10), pp. 1789-1794. Date of Electronic Publication: 2020 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Association Studies*
Cardiovascular Diseases/*genetics
Cardiovascular Diseases/*mortality
Genetic Predisposition to Disease/*genetics
Lipase/*genetics
Membrane Proteins/*genetics
Polymorphism, Genetic/*genetics
Adult ; Alleles ; Cardiovascular Diseases/epidemiology ; Comorbidity ; Female ; Follow-Up Studies ; Genotype ; Humans ; Male ; Non-alcoholic Fatty Liver Disease/mortality ; Risk Factors ; Time Factors ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Association of ANRIL Polymorphism With Overall Survival in Adult Patients With Hematologic Malignancies After Allogeneic Hematopoietic Stem Cell Transplantation.
Autorzy :
Li J; Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, Columbus, OH, U.S.A .; Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, U.S.A.
Seligson N; Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, Columbus, OH, U.S.A.; Department of Pharmacy, The Ohio State University Wexner Medical Center, Columbus, OH, U.S.A.
Zhang X; Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, Columbus, OH, U.S.A.
Johnson J; Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, Columbus, OH, U.S.A.
Vangundy Z; Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, Columbus, OH, U.S.A.
Wang D; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, U.S.A.
Phelps M; Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, U.S.A.; Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, U.S.A.
Hofmeister C; Department of Hematology & Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, U.S.A.
Sadee W; Department of Cancer Biology and Genetics, Center for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus, OH, U.S.A.
Poi MJ; Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, Columbus, OH, U.S.A.; Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, U.S.A.; Department of Pharmacy, The Ohio State University Wexner Medical Center, Columbus, OH, U.S.A.
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Źródło :
Anticancer research [Anticancer Res] 2020 Oct; Vol. 40 (10), pp. 5707-5713.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Association Studies*
Genetic Predisposition to Disease*
Hematologic Neoplasms/*genetics
RNA, Long Noncoding/*genetics
Acute Kidney Injury/etiology ; Acute Kidney Injury/genetics ; Acute Kidney Injury/pathology ; Aged ; Female ; Genotype ; Graft vs Host Disease/etiology ; Graft vs Host Disease/genetics ; Graft vs Host Disease/pathology ; Hematologic Neoplasms/complications ; Hematologic Neoplasms/pathology ; Hematologic Neoplasms/therapy ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Progression-Free Survival ; Tacrolimus/pharmacokinetics ; Transplantation, Homologous/adverse effects
Czasopismo naukowe
Tytuł :
Glioblastomas harboring gene fusions detected by next-generation sequencing.
Autorzy :
Woo HY; Department of Pathology, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-gu, Seoul, 03722, South Korea.
Na K; Department of Pathology, Kyung Hee University Hospital, 26 Kyungheedae-Ro, Dongdaemun-gu, Seoul, 02447, South Korea.
Yoo J; Department of Neurosurgery, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-gu, Seoul, 03722, South Korea.
Chang JH; Department of Neurosurgery, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-gu, Seoul, 03722, South Korea.
Park YN; Department of Pathology, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-gu, Seoul, 03722, South Korea.
Shim HS; Department of Pathology, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-gu, Seoul, 03722, South Korea.
Kim SH; Department of Pathology, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-gu, Seoul, 03722, South Korea. .
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Źródło :
Brain tumor pathology [Brain Tumor Pathol] 2020 Oct; Vol. 37 (4), pp. 136-144. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Association Studies*
High-Throughput Nucleotide Sequencing*
Brain Neoplasms/*genetics
Gene Fusion/*genetics
Glioblastoma/*genetics
Glioma/*genetics
Proto-Oncogene Proteins c-met/*genetics
Receptor-Like Protein Tyrosine Phosphatases, Class 5/*genetics
Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Brain Neoplasms/mortality ; Brain Neoplasms/pathology ; Cytoskeletal Proteins/genetics ; Female ; Glioblastoma/mortality ; Glioblastoma/pathology ; Glioma/mortality ; Glioma/pathology ; Humans ; Isocitrate Dehydrogenase/genetics ; Male ; Middle Aged ; Prognosis ; Proto-Oncogene Proteins c-ret/genetics ; Survival Rate
Czasopismo naukowe
Tytuł :
Genotype-phenotype correlations among TP53 carriers: Literature review and analysis of probands undergoing multi-gene panel testing and single-gene testing.
Autorzy :
Fortuno C; QIMR Berghofer Medical Research Institute, Genetics and Computational Division, 300 Herston Rd, Herston, QLD 4006, Australia.
Pesaran T; Ambry Genetics, AlisoViejo, CA, USA.
Mester J; GeneDx, Gaithersburg, MD, USA.
Dolinsky J; Ambry Genetics, AlisoViejo, CA, USA.
Yussuf A; Ambry Genetics, AlisoViejo, CA, USA.
McGoldrick K; Ambry Genetics, AlisoViejo, CA, USA.
James PA; Parkville Familial Cancer Centre, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Australia.
Spurdle AB; QIMR Berghofer Medical Research Institute, Genetics and Computational Division, 300 Herston Rd, Herston, QLD 4006, Australia. Electronic address: .
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Źródło :
Cancer genetics [Cancer Genet] 2020 Oct; Vol. 248-249, pp. 11-17. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Genetic Association Studies*
Germ-Line Mutation*
Biomarkers, Tumor/*genetics
Genetic Testing/*methods
Li-Fraumeni Syndrome/*pathology
Neoplasms/*pathology
Tumor Suppressor Protein p53/*genetics
Adult ; Female ; Humans ; Li-Fraumeni Syndrome/genetics ; Male ; Neoplasms/genetics ; Prognosis ; Survival Rate
Czasopismo naukowe
Tytuł :
Low STMN1 is associated with better prognosis in Asian patients with esophageal cancers: A meta-analysis.
Autorzy :
Cao S; Department of Molecular Pathology, Anyang Tumor Hospital, The Fourth Affiliated Hospital of Henan University of Science and Technology, Anyang, China.
Zhang W; Department of Pathology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shen P; Department of Pathology, Zhengzhou University Affiliated Tumor Hospital, Zhengzhou, China.
Xu R; Department of Medicine, Anyang Tumor Hospital, The Fourth Affiliated Hospital of Henan University of Science and Technology, Anyang, China.
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Źródło :
Journal of gastroenterology and hepatology [J Gastroenterol Hepatol] 2020 Oct; Vol. 35 (10), pp. 1668-1675. Date of Electronic Publication: 2020 Apr 26.
Typ publikacji :
Journal Article; Meta-Analysis
MeSH Terms :
Gene Expression*
Gene Expression Regulation*
Genetic Association Studies*
Carcinoma/*genetics
Esophageal Neoplasms/*genetics
Stathmin/*genetics
Stathmin/*metabolism
Asian Continental Ancestry Group ; Carcinoma/mortality ; Carcinoma/pathology ; Disease-Free Survival ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Tytuł :
Analysis of the BRAF and MAP2K1 mutations in patients with Langerhans cell histiocytosis in Japan.
Autorzy :
Hayase T; Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Saito S; Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Shioda Y; Department of Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
Imamura T; Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Watanabe K; Department of Hematology and Oncology, Shizuoka Children's Hospital, Shizuoka, Japan.
Ohki K; Department of Pediatric Hematology and Oncology Research, National Research Institute for Child Health and Development, Tokyo, Japan.
Yoshioka T; Department of Pathology, National Center for Child Health and Development, Tokyo, Japan.
Oh Y; Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Kawahara Y; Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Niijima H; Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Imashuku S; Division of Laboratory Medicine, Uji Tokushukai Medical Center, Uji, Japan.
Morimoto A; Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan. .
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Źródło :
International journal of hematology [Int J Hematol] 2020 Oct; Vol. 112 (4), pp. 560-567. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Association Studies*
Mutation*
Histiocytosis, Langerhans-Cell/*genetics
MAP Kinase Kinase 1/*genetics
Proto-Oncogene Proteins B-raf/*genetics
Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Japan ; MAP Kinase Signaling System/genetics ; Male
Czasopismo naukowe
Tytuł :
Association of Caspase-8 Genotypes With the Risk for Nasopharyngeal Carcinoma in Taiwan.
Autorzy :
Shih LC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; Department of Otorhinolaryngology, China Medical University Hospital, Taichung, Taiwan, R.O.C.; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Tsai CW; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Chang WS; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Shen TC; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Wang YC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Yang JS; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Lin ML; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan, R.O.C.
Wang ZH; Department of Food Nutrition and Health Biotechnology, Asia University, Taichung, Taiwan, R.O.C. .
Bau DT; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C. .; Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan, R.O.C.
Pokaż więcej
Źródło :
Anticancer research [Anticancer Res] 2020 Oct; Vol. 40 (10), pp. 5503-5508.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Association Studies*
Genetic Predisposition to Disease*
Caspase 8/*genetics
Nasopharyngeal Carcinoma/*genetics
Alleles ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Nasopharyngeal Carcinoma/epidemiology ; Nasopharyngeal Carcinoma/pathology ; Polymorphism, Restriction Fragment Length/genetics ; Polymorphism, Single Nucleotide/genetics ; Promoter Regions, Genetic/genetics ; Risk Factors ; Smoking ; Taiwan
Czasopismo naukowe
Tytuł :
In vivo functional screening for systems-level integrative cancer genomics.
Autorzy :
Weber J; Institute of Molecular Oncology and Functional Genomics, TUM School of Medicine, Technische Universität München, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technische Universität München, Munich, Germany.
Braun CJ; Institute of Molecular Oncology and Functional Genomics, TUM School of Medicine, Technische Universität München, Munich, Germany.; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Saur D; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technische Universität München, Munich, Germany.; Institute of Translational Cancer Research and Experimental Cancer Therapy, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.; Department of Medicine II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Rad R; Institute of Molecular Oncology and Functional Genomics, TUM School of Medicine, Technische Universität München, Munich, Germany. .; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technische Universität München, Munich, Germany. .; Department of Medicine II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. .; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. .
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Źródło :
Nature reviews. Cancer [Nat Rev Cancer] 2020 Oct; Vol. 20 (10), pp. 573-593. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Genetic Association Studies*/methods
Genetic Predisposition to Disease*
Genomics*/methods
Neoplasms/*diagnosis
Neoplasms/*genetics
Animals ; CRISPR-Cas Systems ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Viral ; DNA Transposable Elements ; Early Detection of Cancer ; Genetic Testing/methods ; Humans ; Mutagenesis/drug effects ; Mutagenesis/radiation effects ; Neoplasms/therapy ; Translational Medical Research
Czasopismo naukowe

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