Temat: "Genetic Therapy" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Adenoviral Gene Therapy Vectors in Clinical Use-Basic Aspects with a Special Reference to Replication-Competent Adenovirus Formation and Its Impact on Clinical Safety.
Autorzy:: Leikas AJ; Heart Center, Kuopio University Hospital, 70200 Kuopio, Finland.; Gene Therapy Unit, Kuopio University Hospital, 70200 Kuopio, Finland.; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland.
Ylä-Herttuala S; Heart Center, Kuopio University Hospital, 70200 Kuopio, Finland.; Gene Therapy Unit, Kuopio University Hospital, 70200 Kuopio, Finland.; A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland.
Hartikainen JEK; Heart Center, Kuopio University Hospital, 70200 Kuopio, Finland.; Gene Therapy Unit, Kuopio University Hospital, 70200 Kuopio, Finland.; School of Medicine, Faculty of Health Sciences, University of Eastern Finland, 70210 Kuopio, Finland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 20; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Adenoviridae*/genetics
Genetic Vectors*/genetics
Humans ; HEK293 Cells ; Genetic Therapy/adverse effects ; Genetic Therapy/methods ; Virus Replication/genetics

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Skocz do pozycji: 2.

Tytuł:: Caridac vein retroinjections provide an efficient approach for global left ventricular gene transfer with adenovirus and adeno-associated virus.
Autorzy:: Lampela J; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Pajula J; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Järveläinen N; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Siimes S; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Laham-Karam N; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Kivelä A; Heart Hospital, Tampere University Hospital, Tampere, Finland.
Mushimiyimana I; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Nurro J; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Hartikainen J; Heart Center, Kuopio University Hospital, Kuopio, Finland.
Ylä-Herttuala S; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland. .; Heart Center, Kuopio University Hospital, Kuopio, Finland. .; Gene Therapy Unit, Kuopio University Hospital, Kuopio, Finland. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Jan 17; Vol. 14 (1), pp. 1467. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:: Journal Article
MeSH Terms:: Adenoviridae*/genetics
Adenoviridae Infections*
Humans ; Dependovirus/genetics ; Gene Transfer Techniques ; Genetic Therapy/methods ; Myocardium ; Genetic Vectors/genetics

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Skocz do pozycji: 3.

Tytuł:: Adenovirus-Based Gene Therapy for Bone Regeneration: A Comparative Analysis of In Vivo and Ex Vivo BMP2 Gene Delivery.
Autorzy:: Bukharova TB; Research Centre for Medical Genetics, 115478 Moscow, Russia.
Nedorubova IA; Research Centre for Medical Genetics, 115478 Moscow, Russia.
Mokrousova VO; Research Centre for Medical Genetics, 115478 Moscow, Russia.
Meglei AY; Research Centre for Medical Genetics, 115478 Moscow, Russia.
Basina VP; Research Centre for Medical Genetics, 115478 Moscow, Russia.
Nedorubov AA; Institute of Translational Medicine and Biotechnology and E.V. Borovsky Institute of Dentistry, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russia.
Vasilyev AV; Research Centre for Medical Genetics, 115478 Moscow, Russia.; Institute of Translational Medicine and Biotechnology and E.V. Borovsky Institute of Dentistry, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russia.
Grigoriev TE; NRC 'Kurchatov Institute', 123182 Moscow, Russia.
Zagoskin YD; NRC 'Kurchatov Institute', 123182 Moscow, Russia.
Chvalun SN; NRC 'Kurchatov Institute', 123182 Moscow, Russia.
Kutsev SI; Research Centre for Medical Genetics, 115478 Moscow, Russia.
Goldshtein DV; Research Centre for Medical Genetics, 115478 Moscow, Russia.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Jul 01; Vol. 12 (13). Date of Electronic Publication: 2023 Jul 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Osteogenesis*/genetics
Adenoviridae*/genetics
Bone Regeneration/genetics ; Genetic Therapy ; Fibrin

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Skocz do pozycji: 4.

Tytuł:: Adenovirus Biology, Recombinant Adenovirus, and Adenovirus Usage in Gene Therapy.
Autorzy:: Watanabe M; Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.
Nishikawaji Y; Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.
Kawakami H; Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.
Kosai KI; Department of Gene Therapy and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.; South Kyushu Center for Innovative Medical Research and Application, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.; Center for Innovative Therapy Research and Application, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.; Center for Clinical and Translational Research, Kagoshima University Hospital, Kagoshima 890-8544, Japan.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 Dec 14; Vol. 13 (12). Date of Electronic Publication: 2021 Dec 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Genetic Therapy*
Adenoviridae/*genetics
Adenoviridae/*physiology
Adenoviridae Infections/*virology
COVID-19/*prevention & control
Animals ; COVID-19 Vaccines ; Cell Line, Tumor ; Gene Expression ; Genetic Vectors ; Humans ; Immunotherapy ; Oncolytic Viruses/genetics ; Pluripotent Stem Cells ; Promoter Regions, Genetic ; SARS-CoV-2 ; Survivin ; Virus Replication

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Skocz do pozycji: 5.

Tytuł:: Significance of Preexisting Vector Immunity and Activation of Innate Responses for Adenoviral Vector-Based Therapy.
Autorzy:: Wang WC; Department of Comparative Pathobiology, Purdue Institute of Immunology, Inflammation and Infectious Disease, Purdue University Center for Cancer Research, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.
Sayedahmed EE; Department of Comparative Pathobiology, Purdue Institute of Immunology, Inflammation and Infectious Disease, Purdue University Center for Cancer Research, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.
Mittal SK; Department of Comparative Pathobiology, Purdue Institute of Immunology, Inflammation and Infectious Disease, Purdue University Center for Cancer Research, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2022 Dec 06; Vol. 14 (12). Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Adenoviridae*/genetics
Adenoviridae Infections*
Humans ; Genetic Therapy ; Vaccination ; Transgenes ; Genetic Vectors/genetics ; Immunity, Innate

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Skocz do pozycji: 6.

Tytuł:: Efficient Intravenous Tumor Targeting Using the αvβ6 Integrin-Selective Precision Virotherapy Ad5 NULL -A20.
Autorzy:: Davies JA; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Marlow G; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Uusi-Kerttula HK; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Seaton G; School of Biosciences, Cardiff University, Cardiff CF24 4HQ, UK.
Piggott L; School of Biosciences, Cardiff University, Cardiff CF24 4HQ, UK.
Badder LM; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Clarkson RWE; School of Biosciences, Cardiff University, Cardiff CF24 4HQ, UK.
Chester JD; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.; Velindre Cancer Centre, Cardiff CF14 2TL, UK.
Parker AL; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 May 08; Vol. 13 (5). Date of Electronic Publication: 2021 May 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Therapy*/methods
Oncolytic Virotherapy*/methods
Adenoviridae/*genetics
Antigens, Neoplasm/*genetics
Genetic Vectors/*genetics
Integrins/*genetics
Neoplasms/*therapy
Oncolytic Viruses/*genetics
Administration, Intravenous ; Animals ; Cell Line, Tumor ; Cell Survival ; Disease Models, Animal ; Genetic Vectors/administration & dosage ; Humans ; Mice ; Neoplasms/etiology ; Transduction, Genetic ; Treatment Outcome ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 7.

Tytuł:: Lacrimal Gland as a Target Organ for Adenovirus Gene Therapy Encoding Erythropoietin for Dry Eye Induced by Benzalkonium Chloride.
Autorzy:: Dias LC; Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto, SP, Brazil.
Zheng C; Molecular Physiology and Therapeutic Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health Bethesda, Bethesda, Maryland, USA.
Murashima AAB; Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto, SP, Brazil.
Dias AC; Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto, SP, Brazil.
Fantucci MZ; Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto, SP, Brazil.
Nominato LF; Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto, SP, Brazil.
da Silva LECM; Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto, SP, Brazil.
Rocha EM; Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto, SP, Brazil.; Pokaż więcej
Źródło:: Current eye research [Curr Eye Res] 2021 Sep; Vol. 46 (9), pp. 1314-1319. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenoviridae/*genetics
Dry Eye Syndromes/*therapy
Erythropoietin/*genetics
Genetic Therapy/*methods
Lacrimal Apparatus/*diagnostic imaging
Animals ; Benzalkonium Compounds/toxicity ; Disease Models, Animal ; Dry Eye Syndromes/chemically induced ; Dry Eye Syndromes/diagnosis ; Erythropoietin/metabolism ; Genetic Vectors ; Lacrimal Apparatus/drug effects ; Lacrimal Apparatus/metabolism ; Male ; Rats ; Rats, Wistar ; Tears/metabolism

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Skocz do pozycji: 8.

Tytuł:: On the Relationship of Viral Particles and Extracellular Vesicles: Implications for Viral Vector Technology.
Autorzy:: Metzner C; Institute of Virology, University of Veterinary Medicine, 1210 Vienna, Austria.
Zaruba M; Institute of Virology, University of Veterinary Medicine, 1210 Vienna, Austria.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 Jun 26; Vol. 13 (7). Date of Electronic Publication: 2021 Jun 26.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Extracellular Vesicles*
Genetic Vectors*
Adenoviridae/*genetics
Dependovirus/*genetics
Retroviridae/*genetics
Adenoviridae/physiology ; Dependovirus/physiology ; Genetic Therapy ; Humans ; Lentivirus/genetics ; Retroviridae/physiology ; Virus Diseases/virology

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Skocz do pozycji: 9.

Tytuł:: Oncolytic Adenoviruses for Cancer Therapy.
Autorzy:: Tripodi L; SEMM European School for Molecular Medicine, 20123 Milano, Italy.; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.
Vitale M; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, 80131 Napoli, Italy.
Cerullo V; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, 80131 Napoli, Italy.; Laboratory of Immunovirotherapy, Drug Research Program, Faculty of Pharmacy, University of Helsinki, 00014 Helsinki, Finland.
Pastore L; CEINGE Biotecnologie Avanzate, 80145 Naples, Italy.; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, 80131 Napoli, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Mar 03; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 03.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Adenoviridae/*genetics
Neoplasms/*therapy
Neoplasms/*virology
Oncolytic Virotherapy/*methods
Oncolytic Viruses/*genetics
Animals ; Genetic Therapy/methods ; Humans ; T-Lymphocytes/virology ; Tumor Microenvironment/genetics

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Skocz do pozycji: 10.

Tytuł:: Adenovirus vectored IFN-α protects mice from lethal challenge of Chikungunya virus infection.
Autorzy:: Chen H; Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Infectious Disease Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Min N; Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Infectious Disease Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Ma L; Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Infectious Disease Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Mok CK; Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Infectious Disease Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chu JJH; Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Infectious Disease Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Collaborative and Translation Unit for HFMD, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Dec 03; Vol. 14 (12), pp. e0008910. Date of Electronic Publication: 2020 Dec 03 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenoviridae*
Genetic Vectors*
Chikungunya Fever/*therapy
Interferon-alpha/*pharmacology
Animals ; Chikungunya virus ; Genetic Therapy ; Mice ; Mice, Inbred BALB C ; Viral Load

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Skocz do pozycji: 11.

Tytuł:: Protective effect of hypoxia inducible factor-1α gene therapy using recombinant adenovirus in cerebral ischaemia-reperfusion injuries in rats.
Autorzy:: Li YQ; Department of Emergency, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Hui ZR; Department of Rehabilitation Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Tao T; Department of Rehabilitation Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Shao KY; Department of Neurology, Chengdu Aerospace Hospital, Chengdu, Sichuan Province, China.
Liu Z; Department of Pharmacy, Affiliated Hospital, Guizhou Medical University, Guiyang, Guizhou Province, China.
Li M; Department of Rehabilitation Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Gu LL; Department of Rehabilitation Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 438-446.
Typ publikacji:: Journal Article
MeSH Terms:: Adenoviridae/*genetics
Brain Ischemia/*genetics
Genetic Therapy/*methods
Hypoxia-Inducible Factor 1, alpha Subunit/*genetics
Neuroprotection/*genetics
Reperfusion Injury/*genetics
Animals ; Brain Ischemia/therapy ; Hypoxia-Inducible Factor 1, alpha Subunit/administration & dosage ; Infusions, Intraventricular ; Male ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/therapy

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Skocz do pozycji: 12.

Tytuł:: Inhibitors of metalloprotease, γ-sectretase, protein kinase C and Rho kinase inhibit wild-type adenoviral replication.
Autorzy:: Liu A; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.; Summer Undergraduate Research Training Program, Baylor College of Medicine, Houston, Texas, United States of America.
Ildefonso CJ; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.; Translational Biology and Molecular Medicine Program, Baylor College of Medicine, Houston, Texas, United States of America.
Bond WS; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.; Translational Biology and Molecular Medicine Program, Baylor College of Medicine, Houston, Texas, United States of America.
Hurwitz MY; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.
Hurwitz RL; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.; Summer Undergraduate Research Training Program, Baylor College of Medicine, Houston, Texas, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Jul 22; Vol. 15 (7), pp. e0236175. Date of Electronic Publication: 2020 Jul 22 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenoviridae/*drug effects
Adenoviridae Infections/*drug therapy
Antiviral Agents/*pharmacology
Genetic Vectors/*drug effects
Virus Replication/*drug effects
Adenoviridae/physiology ; Adenoviridae Infections/virology ; Administration, Ophthalmic ; Amides/pharmacology ; Amides/therapeutic use ; Antiviral Agents/therapeutic use ; Conjunctiva/metabolism ; DNA, Viral/genetics ; DNA, Viral/isolation & purification ; Diamines/pharmacology ; Diamines/therapeutic use ; Dipeptides/pharmacology ; Dipeptides/therapeutic use ; Genetic Therapy/methods ; Genetic Vectors/administration & dosage ; Genetic Vectors/physiology ; HeLa Cells ; Humans ; Hyaluronan Receptors/metabolism ; Hyaluronic Acid/metabolism ; Hydroxamic Acids/pharmacology ; Hydroxamic Acids/therapeutic use ; Indoles/pharmacology ; Indoles/therapeutic use ; Maleimides/pharmacology ; Maleimides/therapeutic use ; Metalloproteases/antagonists & inhibitors ; Metalloproteases/metabolism ; Permeability ; Protein Kinase C/antagonists & inhibitors ; Protein Kinase C/metabolism ; Proteolysis/drug effects ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Signal Transduction/drug effects ; Thiazoles/pharmacology ; Thiazoles/therapeutic use ; Versicans/metabolism ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Vitreous Body/metabolism ; rho-Associated Kinases/metabolism

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Skocz do pozycji: 13.

Tytuł:: Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness.
Autorzy:: Farrera-Sal M; ProCure Program, Institut Català d'Oncologia, and Oncobell Program IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.; VCN Biosciences S.L., 08174 Sant Cugat, Spain.
de Sostoa J; ProCure Program, Institut Català d'Oncologia, and Oncobell Program IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.
Nuñez-Manchón E; Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Universitat de Barcelona, 08036 Barcelona, Spain.
Moreno R; ProCure Program, Institut Català d'Oncologia, and Oncobell Program IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.
Fillat C; Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Universitat de Barcelona, 08036 Barcelona, Spain.
Bazan-Peregrino M; VCN Biosciences S.L., 08174 Sant Cugat, Spain.
Alemany R; ProCure Program, Institut Català d'Oncologia, and Oncobell Program IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 21; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 21.
Typ publikacji:: Journal Article
MeSH Terms:: Adenoviridae/*genetics
Genetic Therapy/*methods
Oncolytic Viruses/*genetics
Virus Replication/*genetics
Adenoviridae/metabolism ; Animals ; Cell Line, Tumor ; Codon Usage ; Genes, Reporter ; Genetic Vectors ; Humans ; Mice ; Oncolytic Viruses/metabolism ; Principal Component Analysis ; Promoter Regions, Genetic ; Transgenes ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 14.

Tytuł:: Non-Human Primate-Derived Adenoviruses for Future Use as Oncolytic Agents?
Autorzy:: Bots STF; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Hoeben RC; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 08; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 08.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Adenoviridae/*genetics
Oncolytic Viruses/*genetics
Animals ; Genetic Therapy/methods ; Genetic Vectors/genetics ; Humans ; Oncolytic Virotherapy/methods ; Virus Replication/genetics

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Skocz do pozycji: 15.

Tytuł:: Recombinant adenovirus p53 combined with radiotherapy improves efficacy and safety in the treatment of head and neck lymphoma.
Autorzy:: Xu YH; Department of Radiotherapy, Weifang People's Hospital, Weifang 261000, Shandong, China.
Liu SH; Department of Outpatient, Weifang People's Hospital, Weifang 261000, Shandong, China.
Hao FR; Department of Radiotherapy, Weifang People's Hospital, Weifang 261000, Shandong, China.
Zhang YH; The 2n⁢d Department of Cardiology, Weifang People's Hospital, Weifang 261000, Shandong, China.; Pokaż więcej
Źródło:: Cancer biomarkers : section A of Disease markers [Cancer Biomark] 2018; Vol. 23 (2), pp. 213-220.
Typ publikacji:: Journal Article
MeSH Terms:: Genetic Therapy*
Radiotherapy*
Adenoviridae/*genetics
Genetic Vectors/*genetics
Head and Neck Neoplasms/*genetics
Head and Neck Neoplasms/*therapy
Lymphoma/*genetics
Lymphoma/*therapy
Tumor Suppressor Protein p53/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers ; Combined Modality Therapy ; Female ; Genetic Vectors/administration & dosage ; Head and Neck Neoplasms/diagnosis ; Humans ; Lymphoma/diagnosis ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; Treatment Outcome ; Young Adult

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Skocz do pozycji: 16.

Tytuł:: Effect of the adenovirus‑mediated Wip1 gene on lumbar intervertebral disc degeneration in a rabbit model.
Autorzy:: Wang Y; Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai 200003, P.R. China.
Yang Y; Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai 200003, P.R. China.
Sun JC; Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai 200003, P.R. China.
Kong QJ; Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai 200003, P.R. China.
Wang HB; Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai 200003, P.R. China.
Shi JG; Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai 200003, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 Dec; Vol. 16 (6), pp. 9487-9493. Date of Electronic Publication: 2017 Oct 12.
Typ publikacji:: Journal Article
MeSH Terms:: Genetic Therapy*
Adenoviridae/*metabolism
Intervertebral Disc Degeneration/*therapy
Lumbar Vertebrae/*pathology
Protein Phosphatase 2C/*genetics
Animals ; Cell Proliferation ; Collagen Type II/metabolism ; Disease Models, Animal ; Genetic Vectors/metabolism ; Intervertebral Disc Degeneration/diagnostic imaging ; Intervertebral Disc Degeneration/pathology ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/metabolism ; Nucleus Pulposus/metabolism ; Nucleus Pulposus/pathology ; Proteoglycans/metabolism ; Rabbits ; Transfection

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Skocz do pozycji: 17.

Tytuł:: High-Capacity Adenoviral Vectors Permit Robust and Versatile Testing of DMD Gene Repair Tools and Strategies in Human Cells.
Autorzy:: Brescia M; Department of Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.
Janssen JM; Department of Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.
Liu J; Department of Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.
Gonçalves MAFV; Department of Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Apr 02; Vol. 9 (4). Date of Electronic Publication: 2020 Apr 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenoviridae/*genetics
Gene Editing/*methods
Genetic Therapy/*methods
Genetic Vectors/*genetics
Muscular Dystrophy, Duchenne/*genetics
Humans ; Muscular Dystrophy, Duchenne/pathology

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Skocz do pozycji: 18.

Tytuł:: Sustained Release of Decoy Wnt Receptor (sLRP6E1E2)-Expressing Adenovirus Using Gel-Encapsulation for Scar Remodeling in Pig Model.
Autorzy:: Yang CE; Department of Plastic & Reconstructive Surgery, Wonju College of Medicine, Yonsei University, Wonju 26426, Korea.
Choi S; Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine, Seoul 03722, Korea.
Lee JH; Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Korea.
Kang EH; Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine, Seoul 03722, Korea.
Ahn HM; Department of Bioengineering, College of Engineering, Hanyang University, Seoul 04763, Korea.
Roh TS; Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine, Seoul 03722, Korea.
Yun CO; Department of Bioengineering, College of Engineering, Hanyang University, Seoul 04763, Korea.; Institute of Nano Science and Technology (INST), Hanyang University, Seoul 04763, Korea.
Lee WJ; Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine, Seoul 03722, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Mar 24; Vol. 21 (6). Date of Electronic Publication: 2020 Mar 24.
Typ publikacji:: Journal Article
MeSH Terms:: Adenoviridae/*genetics
Alginates/*chemistry
Cicatrix/*therapy
Genetic Therapy/*methods
Receptors, Wnt/*genetics
Animals ; Collagen/genetics ; Collagen/metabolism ; Gene Transfer Techniques ; Hydrogels/chemistry ; Receptors, Wnt/metabolism ; Skin/metabolism ; Swine ; Wnt Signaling Pathway

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Skocz do pozycji: 19.

Tytuł:: Adenovirus vector‑mediated in vivo gene transfer of nuclear factor erythroid‑2p45‑related factor 2 promotes functional recovery following spinal cord contusion.
Autorzy:: Zhu FC; Department of Orthopaedics, Yongchuan Affiliated Hospital, Chongqing Medical University, Chongqing 402160, P.R. China.
Jiang DM; Department of Orthopaedics, The Third Affiliated Hospital, Chongqing Medical University, Chongqing 401120, P.R. China.
Zhang MH; Department of Orthopaedics, Yongchuan Affiliated Hospital, Chongqing Medical University, Chongqing 402160, P.R. China.
Zhao B; Department of Orthopaedics, Yongchuan Affiliated Hospital, Chongqing Medical University, Chongqing 402160, P.R. China.
He C; Department of Orthopaedics, Yongchuan Affiliated Hospital, Chongqing Medical University, Chongqing 402160, P.R. China.
Yang J; Department of Orthopaedics, Yongchuan Affiliated Hospital, Chongqing Medical University, Chongqing 402160, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Nov; Vol. 20 (5), pp. 4285-4292. Date of Electronic Publication: 2019 Sep 16.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression*
Adenoviridae/*genetics
Genetic Vectors/*genetics
NF-E2-Related Factor 2/*genetics
Spinal Cord Injuries/*genetics
Spinal Cord Injuries/*rehabilitation
Animals ; Disease Models, Animal ; Female ; Gene Transfer Techniques ; Genes, Reporter ; Genetic Therapy ; Genetic Vectors/administration & dosage ; Immunohistochemistry ; Male ; Motor Activity ; NF-E2-Related Factor 2/metabolism ; Neuroglia/metabolism ; Neurons/metabolism ; Rats ; Spinal Cord Injuries/therapy ; Transduction, Genetic

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Skocz do pozycji: 20.

Tytuł:: Targeting the gastrointestinal tract with viral vectors: state of the art and possible applications in research and therapy.
Autorzy:: Buckinx R; Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Timmermans JP; Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium. .; Pokaż więcej
Źródło:: Histochemistry and cell biology [Histochem Cell Biol] 2016 Dec; Vol. 146 (6), pp. 709-720. Date of Electronic Publication: 2016 Sep 24.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Genetic Therapy*
Adenoviridae/*genetics
Dependovirus/*genetics
Gastrointestinal Tract/*metabolism
Gastrointestinal Tract/*virology
Genetic Vectors/*genetics
Retroviridae/*genetics
Animals ; Gastrointestinal Tract/cytology ; Humans

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