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Wyszukujesz frazę ""Genomics"" wg kryterium: Temat


Tytuł :
Establishment and implementation of Cancer Genomic Medicine in Japan.
Autorzy :
Mukai Y; Department of Surgery, Osaka International Cancer Institute, Osaka, Japan.; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan.; Cancer and Disease Control Division, Health Service Bureau, Government of Japan Ministry of Health, Labour, and Welfare, Tokyo, Japan.
Ueno H; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Mar; Vol. 112 (3), pp. 970-977. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Health Plan Implementation*
Genomics/*organization & administration
Medical Oncology/*organization & administration
National Health Programs/*organization & administration
Neoplasms/*therapy
Clinical Trials as Topic/organization & administration ; Genetic Counseling/economics ; Genetic Counseling/organization & administration ; Genetic Testing/economics ; Genomics/economics ; Genomics/methods ; Humans ; Japan ; Medical Oncology/economics ; Medical Oncology/methods ; National Health Programs/economics ; Neoplasms/diagnosis ; Neoplasms/economics ; Neoplasms/genetics ; Precision Medicine/economics ; Precision Medicine/methods ; Reimbursement Mechanisms ; Therapies, Investigational/economics
Czasopismo naukowe
Tytuł :
Sequence three million genomes across Africa.
Autorzy :
Wonkam A
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Źródło :
Nature [Nature] 2021 Feb; Vol. 590 (7845), pp. 209-211.
Typ publikacji :
Journal Article
MeSH Terms :
Genomics*/economics
Genomics*/organization & administration
Sequence Analysis, DNA*/economics
African Continental Ancestry Group/*genetics
Genome, Human/*genetics
Africa/ethnology ; Anemia, Sickle Cell/genetics ; Goals ; Hearing Loss/genetics ; Human Genome Project/economics ; Humans
Czasopismo naukowe
Tytuł :
Guiding Genomic Research: Australia's National Statement on Ethical Conduct in Human Research.
Autorzy :
Bennett B; Australian Centre for Health Law Research, School of Law, Queensland University of Technology, Brisbane, Australia.
Dallaston E; Australian Centre for Health Law Research, School of Law, Queensland University of Technology, Brisbane, Australia.
McDonald F; Australian Centre for Health Law Research, School of Law, Queensland University of Technology, Brisbane, Australia.
McGee A; Australian Centre for Health Law Research, School of Law, Queensland University of Technology, Brisbane, Australia.
Then SN; Australian Centre for Health Law Research, School of Law, Queensland University of Technology, Brisbane, Australia.
Allen B; Graduate, School of Law, Queensland University of Technology, Brisbane.
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Źródło :
Journal of law and medicine [J Law Med] 2021 Mar; Vol. 28 (2), pp. 462-474.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Specimen Banks*
Genomics*
Australia ; Child ; Humans ; Informed Consent ; Research Personnel
Czasopismo naukowe
Tytuł :
The future is now? Clinical and translational aspects of "Omics" technologies.
Autorzy :
D'Adamo GL; Centre for Innate Immunity and Infectious Disease, Hudson Institute of Medical Research, Clayton, VIC, Australia.
Widdop JT; Centre for Innate Immunity and Infectious Disease, Hudson Institute of Medical Research, Clayton, VIC, Australia.
Giles EM; Centre for Innate Immunity and Infectious Disease, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Paediatrics, Monash University, Clayton, VIC, Australia.
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Źródło :
Immunology and cell biology [Immunol Cell Biol] 2021 Feb; Vol. 99 (2), pp. 168-176. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genomics/*trends
Metabolomics/*trends
Precision Medicine/*trends
Translational Medical Research/*trends
Artificial Intelligence/trends ; COVID-19/epidemiology ; Genomics/methods ; Humans ; Medical Oncology/methods ; Medical Oncology/trends ; Metabolomics/methods ; Pandemics ; Precision Medicine/methods ; Proteomics/methods ; Proteomics/trends ; Time Factors ; Translational Medical Research/methods
Czasopismo naukowe
Tytuł :
ATAV: a comprehensive platform for population-scale genomic analyses.
Autorzy :
Ren Z; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA. .
Povysil G; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Hostyk JA; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Cui H; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Bhardwaj N; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Goldstein DB; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Mar 23; Vol. 22 (1), pp. 149. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Genomics*
Software*
Whole Exome Sequencing*
Genetics, Population/*instrumentation
Databases, Genetic ; Humans ; Phenotype ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Prioritizing non-coding regions based on human genomic constraint and sequence context with deep learning.
Autorzy :
Vitsios D; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK. .
Dhindsa RS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Middleton L; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Gussow AB; National Center for Biotechnology Information, National Library of Medicine, Bethesda, MD, USA.
Petrovski S; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 08; Vol. 12 (1), pp. 1504. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Deep Learning*
Genome, Human*
Genomics*
DNA, Intergenic ; Genetic Variation ; Humans ; Sequence Analysis, DNA ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response.
Autorzy :
Andrysik Z; Department of Pharmacology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Linda Crnic Institute for Down Syndrome, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Bender H; Department of Pharmacology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Linda Crnic Institute for Down Syndrome, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Galbraith MD; Department of Pharmacology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. .; Linda Crnic Institute for Down Syndrome, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. .
Espinosa JM; Department of Pharmacology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. .; Linda Crnic Institute for Down Syndrome, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. .; Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, CO, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 02; Vol. 12 (1), pp. 1375. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Regulatory Networks*
Genes, Tumor Suppressor*
Genomics*
Oncogenes*
Hypoxia/*genetics
Cell Line, Tumor ; Cell Survival ; Cyclin-Dependent Kinase 8/metabolism ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Genome, Human ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Neoplasms/genetics ; Neoplasms/pathology ; Protein Binding ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Transcription, Genetic ; Transcriptional Activation/genetics ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Genomic investigation of clinically significant coagulase-negative staphylococci.
Autorzy :
Cole K; Brighton and Sussex Medical School, Brighton, UK.; Public Health England Collaborating Centre, Royal Sussex County Hospital, Brighton, UK.
Atkins B; Oxford University Hospitals Trust, Oxford, UK.
Llewelyn M; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.; Brighton and Sussex Medical School, Brighton, UK.
Paul J; Public Health England Collaborating Centre, Royal Sussex County Hospital, Brighton, UK.; Brighton and Sussex Medical School, Brighton, UK.
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Źródło :
Journal of medical microbiology [J Med Microbiol] 2021 Mar; Vol. 70 (3). Date of Electronic Publication: 2021 Mar 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genomics*
Coagulase/*deficiency
Staphylococcal Infections/*microbiology
Staphylococcus/*genetics
Staphylococcus/*isolation & purification
Adaptation, Physiological/genetics ; Bacteremia/diagnosis ; Bacteremia/microbiology ; Drug Resistance, Bacterial/genetics ; Humans ; Prosthesis-Related Infections/diagnosis ; Prosthesis-Related Infections/microbiology ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/transmission ; Staphylococcus/enzymology ; Staphylococcus/pathogenicity ; Virulence/genetics
Czasopismo naukowe
Tytuł :
Million-year-old DNA sheds light on the genomic history of mammoths.
Autorzy :
van der Valk T; Centre for Palaeogenetics, Stockholm, Sweden. .; Department of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden. .; Department of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. .
Pečnerová P; Department of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden.; Department of Zoology, Stockholm University, Stockholm, Sweden.; Section for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Díez-Del-Molino D; Centre for Palaeogenetics, Stockholm, Sweden.; Department of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden.; Department of Zoology, Stockholm University, Stockholm, Sweden.
Bergström A; The Francis Crick Institute, London, UK.
Oppenheimer J; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.
Hartmann S; Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Xenikoudakis G; Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Thomas JA; Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Dehasque M; Centre for Palaeogenetics, Stockholm, Sweden.; Department of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden.; Department of Zoology, Stockholm University, Stockholm, Sweden.
Sağlıcan E; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Fidan FR; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Barnes I; Department of Earth Sciences, Natural History Museum, London, UK.
Liu S; College of Plant Protection, China Agricultural University, Beijing, China.
Somel M; Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.
Heintzman PD; The Arctic University Museum of Norway, UiT - The Arctic University of Norway, Tromsø, Norway.
Nikolskiy P; Geological Institute, Russian Academy of Sciences, Moscow, Russia.
Shapiro B; Department of Ecology and Evolutionary Biology, University of California Santa Cruz, Santa Cruz, CA, USA.; Howard Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, CA, USA.
Skoglund P; The Francis Crick Institute, London, UK.
Hofreiter M; Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Lister AM; Department of Earth Sciences, Natural History Museum, London, UK.
Götherström A; Centre for Palaeogenetics, Stockholm, Sweden.; Department of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Dalén L; Centre for Palaeogenetics, Stockholm, Sweden. .; Department of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden. .; Department of Zoology, Stockholm University, Stockholm, Sweden. .
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Źródło :
Nature [Nature] 2021 Mar; Vol. 591 (7849), pp. 265-269. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Evolution, Molecular*
Genomics*
Phylogeny*
DNA, Ancient/*analysis
Genome, Mitochondrial/*genetics
Mammoths/*genetics
Acclimatization/genetics ; Alleles ; Animals ; Bayes Theorem ; DNA, Ancient/isolation & purification ; Elephants/genetics ; Europe ; Female ; Fossils ; Genetic Variation/genetics ; Markov Chains ; Molar ; North America ; Radiometric Dating ; Siberia ; Time Factors
Czasopismo naukowe
Tytuł :
Examining Natural History through the Lens of Palaeogenomics.
Autorzy :
Mitchell KJ; Australian Centre for Ancient DNA (ACAD), School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia; Australian Research Council (ARC) Centre of Excellence for Australian Biodiversity and Heritage (CABAH), School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia. Electronic address: .
Rawlence NJ; Otago Palaeogenetics Laboratory, Department of Zoology, University of Otago, Dunedin, New Zealand.
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Źródło :
Trends in ecology & evolution [Trends Ecol Evol] 2021 Mar; Vol. 36 (3), pp. 258-267. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Fossils*
Genomics*
Humans ; Paleontology
Czasopismo naukowe
Tytuł :
Genomic, transcriptomic, and protein landscape profile of CFTR and cystic fibrosis.
Autorzy :
Sanders M; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI, 49503, USA.
Lawlor JMJ; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.
Li X; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI, 49503, USA.
Schuen JN; Pediatric Pulmonology, Helen DeVos Children's Hospital, Grand Rapids, MI, 49503, USA.
Millard SL; Pediatric Pulmonology, Helen DeVos Children's Hospital, Grand Rapids, MI, 49503, USA.
Zhang X; Department of Pediatrics, Division of Pulmonary Medicine, National Jewish Health, Denver, CO, 80206, USA.
Buck L; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI, 49503, USA.; Department of Mathematics, University of North Alabama, Florence, AL, 35632, USA.
Grysko B; Spectrum Health Medical Genetics, Grand Rapids, MI, 49503, USA.
Uhl KL; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI, 49503, USA.
Hinds D; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI, 49503, USA.; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.
Stenger CL; Department of Mathematics, University of North Alabama, Florence, AL, 35632, USA.
Morris M; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.
Lamb N; HudsonAlpha Institute for Biotechnology, Huntsville, AL, 35806, USA.
Levy H; Department of Pediatrics, Division of Pulmonary Medicine, National Jewish Health, Denver, CO, 80206, USA.
Bupp C; Spectrum Health Medical Genetics, Grand Rapids, MI, 49503, USA.
Prokop JW; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI, 49503, USA. .; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, 48824, USA. .
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Źródło :
Human genetics [Hum Genet] 2021 Mar; Vol. 140 (3), pp. 423-439. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Genomics*
Transcriptome*
Cystic Fibrosis/*genetics
Cystic Fibrosis Transmembrane Conductance Regulator/*genetics
Amino Acid Substitution ; Cystic Fibrosis Transmembrane Conductance Regulator/chemistry ; Genetic Heterogeneity ; Genome-Wide Association Study ; Humans ; Linkage Disequilibrium ; Mutation ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci
Czasopismo naukowe
Tytuł :
Single-cell multiomics sequencing reveals the functional regulatory landscape of early embryos.
Autorzy :
Wang Y; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China.
Yuan P; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China.
Yan Z; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China.
Yang M; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.
Huo Y; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China.
Nie Y; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China.
Zhu X; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China.
Qiao J; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. .; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China. .; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China. .; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China. .; National Clinical Research Center for Obstetrics and Gynecology, Beijing, China. .; Research Units of Comprehensive Diagnosis and Treatment of Oocyte Maturation Arrest, Beijing, China. .
Yan L; Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. .; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, China. .; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China. .; National Clinical Research Center for Obstetrics and Gynecology, Beijing, China. .; Research Units of Comprehensive Diagnosis and Treatment of Oocyte Maturation Arrest, Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 23; Vol. 12 (1), pp. 1247. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Genomics*
Single-Cell Analysis*
Blastocyst/*metabolism
Embryo, Mammalian/*metabolism
Alleles ; Animals ; Cell Lineage/genetics ; Chromatin/metabolism ; DNA Methylation/genetics ; Ectoderm/cytology ; Female ; Male ; Mice ; Phylogeny ; Promoter Regions, Genetic ; Zygote/metabolism
Czasopismo naukowe
Tytuł :
Uniform genomic data analysis in the NCI Genomic Data Commons.
Autorzy :
Zhang Z; Center for Translational Data Science, University of Chicago, Chicago, IL, USA.
Hernandez K; Center for Translational Data Science, University of Chicago, Chicago, IL, USA.
Savage J; Center for Translational Data Science, University of Chicago, Chicago, IL, USA.; AbbVie Inc., Redwood City, CA, USA.
Li S; Center for Translational Data Science, University of Chicago, Chicago, IL, USA.
Miller D; Center for Translational Data Science, University of Chicago, Chicago, IL, USA.; Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Agrawal S; Center for Translational Data Science, University of Chicago, Chicago, IL, USA.; Merck Healthcare KGaA, Darmstadt, Germany.
Ortuno F; Center for Translational Data Science, University of Chicago, Chicago, IL, USA.; Clinical Bioinformatics Area, Fundacion Progreso y Salud (FPS), Seville, Spain.
Staudt LM; National Cancer Institute, Bethesda, MD, USA.
Heath A; Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Grossman RL; Center for Translational Data Science, University of Chicago, Chicago, IL, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 22; Vol. 12 (1), pp. 1226. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Data Analysis*
Databases, Genetic*
Genomics*
Base Sequence ; DNA Copy Number Variations/genetics ; DNA Methylation/genetics ; Gene Expression Regulation ; Genome, Human ; Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Molecular Sequence Annotation ; Mutation/genetics ; National Cancer Institute (U.S.) ; RNA-Seq ; Reproducibility of Results ; United States ; Viruses/genetics
Czasopismo naukowe
Tytuł :
Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Autorzy :
Iftekhar A; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Berger H; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.; Laboratory of Infection Oncology, Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel and University Hospital Schleswig Holstein - Campus Kiel, Kiel, Germany.; Department of Internal Medicine, Gastroenterology and Hepatology, Charité University Medicine, Berlin, Germany.
Bouznad N; Experimental and Molecular Pathology, Institute of Pathology, Ludwig Maximilians University, München, Germany.
Heuberger J; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.; Department of Internal Medicine, Gastroenterology and Hepatology, Charité University Medicine, Berlin, Germany.
Boccellato F; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK.
Dobrindt U; Institute of Hygiene, University of Münster, Münster, Germany.
Hermeking H; Experimental and Molecular Pathology, Institute of Pathology, Ludwig Maximilians University, München, Germany.; German Cancer Consortium (DKTK), Partner Site München, München, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sigal M; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany. .; Department of Internal Medicine, Gastroenterology and Hepatology, Charité University Medicine, Berlin, Germany. .; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany. .
Meyer TF; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany. .; Laboratory of Infection Oncology, Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel and University Hospital Schleswig Holstein - Campus Kiel, Kiel, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 12; Vol. 12 (1), pp. 1003. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genomics*
Epithelial Cells/*metabolism
Escherichia coli/*metabolism
Peptides/*metabolism
Polyketides/*metabolism
Animals ; Chromosome Aberrations ; Colon/pathology ; Colonic Neoplasms/genetics ; Colonic Neoplasms/pathology ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/psychology ; DNA Damage ; Epithelial Cells/pathology ; Escherichia coli/genetics ; Male ; Mice ; Mice, Knockout ; Mutation ; Organoids ; Peptides/genetics
Czasopismo naukowe
Tytuł :
Multiple mechanisms drive genomic adaptation to extreme O 2 levels in Drosophila melanogaster.
Autorzy :
Iranmehr A; Department of Electrical & Computer Engineering, University of California, San Diego, La Jolla, CA, USA.
Stobdan T; Division of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.
Zhou D; Division of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA. .
Zhao H; Division of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.
Kryazhimskiy S; Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
Bafna V; Department of Computer Science & Engineering, University of California, San Diego, La Jolla, CA, USA. .
Haddad GG; Division of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA. .; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA. .; Rady Children's Hospital, San Diego, CA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 12; Vol. 12 (1), pp. 997. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Genome, Insect*
Genomics*
Adaptation, Physiological/*genetics
Drosophila melanogaster/*genetics
Oxygen/*metabolism
Alleles ; Animals ; Evolution, Molecular ; Female ; Gene Frequency ; Haplotypes ; Male ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Ranking cancer drivers via betweenness-based outlier detection and random walks.
Autorzy :
Erten C; Department of Computer Engineering, Antalya Bilim University, Antalya, Turkey.
Houdjedj A; Electrical and Computer Engineering Graduate Program, Antalya Bilim University, Antalya, Turkey.
Kazan H; Department of Computer Engineering, Antalya Bilim University, Antalya, Turkey. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Feb 10; Vol. 22 (1), pp. 62. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article
MeSH Terms :
Genomics*
Neoplasms*/genetics
Oncogenes*
Protein Interaction Maps*
Gene Regulatory Networks ; Humans
Czasopismo naukowe
Tytuł :
In silico drug repositioning based on the integration of chemical, genomic and pharmacological spaces.
Autorzy :
Chen H; School of Software, East China Jiaotong University, Nanchang, 330013, China. .
Zhang Z; School of Computer Science and Engineering, Central South University, Changsha, 410083, China.
Zhang J; School of Computer and Data Science, Henan University of Urban Construction, Pingdingshan, 467000, China.
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Feb 08; Vol. 22 (1), pp. 52. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Repositioning*
Genomics*
Algorithms ; Computational Biology ; Computer Simulation ; Databases, Factual
Czasopismo naukowe
Tytuł :
Characterization of Olfactory Receptor Repertoires in the Endangered Snow Leopard Based on the Chromosome-Level Genome.
Autorzy :
Zhou C; Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu, People's Republic of China.
Wang L; Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu, People's Republic of China.
Qiao L; Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu, People's Republic of China.
Lan Y; Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu, People's Republic of China.
Price M; Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu, People's Republic of China.
Yang N; Institute of Qinghai-Tibetan Plateau, Southwest Minzu University, Chengdu, People's Republic of China.; Collaborative Innovation Center for Ecological Animal Husbandry of Qinghai-Tibetan Plateau, Southwest Minzu University, Chengdu, People's Republic of China.
Yue B; Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu, People's Republic of China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2021 Feb; Vol. 40 (2), pp. 293-302.
Typ publikacji :
Journal Article
MeSH Terms :
Endangered Species*
Genomics*
Panthera*
Chromosomes/*genetics
Receptors, Odorant/*genetics
Amino Acid Sequence ; Animals ; Phylogeny ; Receptors, Odorant/chemistry
Czasopismo naukowe

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