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    Wyświetlanie 1-6 z 6
    Tytuł:
    Attenuation of Adverse Postinfarction Left Ventricular Remodeling with Empagliflozin Enhances Mitochondria-Linked Cellular Energetics and Mitochondrial Biogenesis.
    Autorzy:
    Song Y; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Huang C; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Sin J; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; University of Alabama, Birmingham, AL 35294, USA.
    Germano JF; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Taylor DJR; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Thakur R; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Gottlieb RA; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Mentzer RM Jr; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Andres AM; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Dec 31; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 31.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Energy Metabolism*/drug effects
    Organelle Biogenesis*
    Ventricular Remodeling*/drug effects
    Benzhydryl Compounds/*therapeutic use
    Glucosides/*therapeutic use
    Mitochondria, Heart/*metabolism
    Myocardial Infarction/*drug therapy
    Myocardial Infarction/*physiopathology
    Animals ; Benzhydryl Compounds/pharmacology ; Electrocardiography ; Glucosides/pharmacology ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria, Heart/drug effects ; Mitophagy/drug effects ; Myocardial Infarction/diagnostic imaging ; Ubiquitin-Protein Ligases/deficiency ; Ubiquitin-Protein Ligases/metabolism ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Ultraviolet A light effectively reduces bacteria and viruses including coronavirus.
    Autorzy:
    Rezaie A; Medically Associated Science and Technology (MAST) Program, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
    Leite GGS; Medically Associated Science and Technology (MAST) Program, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
    Melmed GY; Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai, Los Angeles, California, United States of America.
    Mathur R; Medically Associated Science and Technology (MAST) Program, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
    Villanueva-Millan MJ; Medically Associated Science and Technology (MAST) Program, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
    Parodi G; Medically Associated Science and Technology (MAST) Program, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
    Sin J; Cedars-Sinai Heart Institute, Cedars-Sinai, Los Angeles, California, United States of America.
    Germano JF; Cedars-Sinai Heart Institute, Cedars-Sinai, Los Angeles, California, United States of America.
    Morales W; Medically Associated Science and Technology (MAST) Program, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
    Weitsman S; Medically Associated Science and Technology (MAST) Program, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
    Kim SY; Division of Gastroenterology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan, South Korea.
    Park JH; Division of Gastroenterology, Department of Internal Medicine, Ulsan University Hospital, Ulsan, South Korea.
    Sakhaie S; Australian Clinical Labs, Melbourne, Australia.
    Pimentel M; Medically Associated Science and Technology (MAST) Program, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
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    Źródło:
    PloS one [PLoS One] 2020 Jul 16; Vol. 15 (7), pp. e0236199. Date of Electronic Publication: 2020 Jul 16 (Print Publication: 2020).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Bacterial Infections/*therapy
    Mycoses/*therapy
    Opportunistic Infections/*therapy
    Ultraviolet Therapy/*methods
    Virus Diseases/*therapy
    Animals ; Apoptosis/radiation effects ; Bacteria/radiation effects ; Bacterial Infections/microbiology ; Cell Survival/radiation effects ; Colon/microbiology ; Colon/radiation effects ; Coronavirus 229E, Human/radiation effects ; DNA Damage/radiation effects ; Disease Models, Animal ; Enterovirus B, Human/radiation effects ; Female ; HeLa Cells ; Humans ; Intestinal Mucosa/microbiology ; Intestinal Mucosa/radiation effects ; Male ; Mice ; Mycoses/microbiology ; Opportunistic Infections/microbiology ; Primary Cell Culture ; Ultraviolet Therapy/adverse effects ; Virus Diseases/virology ; Yeasts/radiation effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Intermittent Use of a Short-Course Glucagon-like Peptide-1 Receptor Agonist Therapy Limits Adverse Cardiac Remodeling via Parkin-dependent Mitochondrial Turnover.
    Autorzy:
    Germano JF; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Huang C; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Sin J; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Song Y; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Tucker KC; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Taylor DJR; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Saadaeijahromi H; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Stotland A; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Piplani H; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Gottlieb RA; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Mentzer RM Jr; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA.
    Andres AM; Cedars Sinai Medical Center, Smidt Heart Institute, Los Angeles, USA. .; University of California, San Diego, Department of Medicine, San Diego, USA. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 May 19; Vol. 10 (1), pp. 8284. Date of Electronic Publication: 2020 May 19.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Glucagon-Like Peptide-1 Receptor/*agonists
    Mitochondria, Heart/*metabolism
    Myocardial Infarction/*drug therapy
    Quinoxalines/*administration & dosage
    Ubiquitin-Protein Ligases/*genetics
    Ventricular Remodeling/*drug effects
    Animals ; Biomarkers/metabolism ; Cell Line ; Disease Models, Animal ; Heart Function Tests ; Male ; Mice ; Mice, Knockout ; Mitophagy ; Myocardial Infarction/etiology ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Quinoxalines/pharmacology ; Rats
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Antiviral Effects of Menthol on Coxsackievirus B.
    Autorzy:
    Taylor DJR; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Hamid SM; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Andres AM; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Saadaeijahromi H; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Piplani H; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Germano JF; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Song Y; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Sawaged S; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Feuer R; The Integrated Regenerative Research Institute (IRRI) at San Diego State University, San Diego State University, San Diego, CA 92182, USA.
    Pandol SJ; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
    Sin J; The Smidt Heart Institute and the Barbra Streisand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
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    Źródło:
    Viruses [Viruses] 2020 Mar 28; Vol. 12 (4). Date of Electronic Publication: 2020 Mar 28.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiviral Agents/*pharmacology
    Enterovirus B, Human/*drug effects
    Enterovirus B, Human/*physiology
    Menthol/*pharmacology
    Animals ; Cells, Cultured ; Coxsackievirus Infections/drug therapy ; Coxsackievirus Infections/pathology ; Coxsackievirus Infections/virology ; Disease Models, Animal ; Gene Expression ; Genes, Reporter ; Genetic Vectors/genetics ; HeLa Cells ; Host-Pathogen Interactions/drug effects ; Host-Pathogen Interactions/immunology ; Humans ; Mice ; TRPM Cation Channels/agonists ; TRPV Cation Channels/antagonists & inhibitors ; Temperature ; Virus Replication/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Dysregulation of microRNAs and target genes networks in human abdominal aortic aneurysm tissues.
    Autorzy:
    Araujo NNF; Department of Clinical Cardiology, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
    Lin-Wang HT; Laboratory of Molecular Investigation in Cardiology, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
    Germano JF; School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
    Farsky PS; Department of Clinical Cardiology, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
    Feldman A; Department of Clinical Cardiology, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
    Rossi FH; Department of Vascular Surgery, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
    Izukawa NM; Department of Vascular Surgery, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
    Higuchi ML; Laboratory of Cardiac Pathology, Heart Institute, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
    Savioli Neto F; Department of Clinical Cardiology, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
    Hirata MH; Laboratory of Molecular Investigation in Cardiology, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.; School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
    Bertolami MC; Department of Clinical Cardiology, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
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    Źródło:
    PloS one [PLoS One] 2019 Sep 20; Vol. 14 (9), pp. e0222782. Date of Electronic Publication: 2019 Sep 20 (Print Publication: 2019).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Expression Regulation*
    Gene Regulatory Networks*
    Aortic Aneurysm, Abdominal/*genetics
    Gene Expression Profiling/*methods
    MicroRNAs/*genetics
    Adult ; Aged ; Aortic Aneurysm, Abdominal/pathology ; Cohort Studies ; Female ; Humans ; Male ; Middle Aged ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    ABCC3 Polymorphisms and mRNA Expression Influence the Concentration of a Carboxylic Acid Metabolite in Patients on Clopidogrel and Aspirin Therapy.
    Autorzy:
    Luchessi AD; School of Pharmaceutical Science, University of Sao Paulo, Sao Paulo, Brazil.; Department of Clinical and Toxicological Analysis, Federal University of Rio Grande do Norte, Natal, Brazil.
    Concheiro M; Luis Concheiro Institute of Forensic Sciences, University of Santiago de Compostela, Santiago de Compostela, Spain.
    Germano JF; School of Pharmaceutical Science, University of Sao Paulo, Sao Paulo, Brazil.
    Silbiger VN; Department of Clinical and Toxicological Analysis, Federal University of Rio Grande do Norte, Natal, Brazil.
    Bortolin RH; Department of Clinical and Toxicological Analysis, Federal University of Rio Grande do Norte, Natal, Brazil.
    Cruz A; Luis Concheiro Institute of Forensic Sciences, University of Santiago de Compostela, Santiago de Compostela, Spain.
    Quintela O; Department of Madrid, National Institute of Toxicology and Forensic Science, Madrid, Spain.
    Brion M; Genetics of Cardiovascular and Ophthalmological Diseases, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Genomic Medicine, University of Santiago de Compostela, IDIS, CIBERER, Santiago de Compostela, Spain.
    Carracedo A; Genomic Medicine, University of Santiago de Compostela, IDIS, CIBERER, Santiago de Compostela, Spain.
    Iñiguez A; Cardiology Service, Alvaro Cunqueiro Hospital, Vigo, Spain.
    Bravo M; Cardiology Service, Alvaro Cunqueiro Hospital, Vigo, Spain.
    López-Rivadulla M; Luis Concheiro Institute of Forensic Sciences, University of Santiago de Compostela, Santiago de Compostela, Spain.
    Hirata RD; School of Pharmaceutical Science, University of Sao Paulo, Sao Paulo, Brazil.
    Sousa AG; Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil.
    Hirata MH; School of Pharmaceutical Science, University of Sao Paulo, Sao Paulo, Brazil.
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    Źródło:
    Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2017 May; Vol. 120 (5), pp. 466-474. Date of Electronic Publication: 2017 Jan 16.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Aspirin/*administration & dosage
    Multidrug Resistance-Associated Proteins/*genetics
    Platelet Aggregation Inhibitors/*administration & dosage
    Ticlopidine/*analogs & derivatives
    Acute Coronary Syndrome/therapy ; Aged ; Aspirin/pharmacokinetics ; Aspirin/pharmacology ; Carboxylic Acids/metabolism ; Chromatography, Liquid/methods ; Clopidogrel ; Cytochrome P-450 CYP2C19/genetics ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Percutaneous Coronary Intervention/methods ; Platelet Aggregation Inhibitors/pharmacokinetics ; Platelet Aggregation Inhibitors/pharmacology ; Polymorphism, Genetic ; RNA, Messenger/metabolism ; Salicylic Acid/metabolism ; Tandem Mass Spectrometry/methods ; Ticlopidine/administration & dosage ; Ticlopidine/pharmacokinetics ; Ticlopidine/pharmacology ; Up-Regulation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-6 z 6

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