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Wyszukujesz frazę ""Ghrelin"" wg kryterium: Temat


Tytuł :
Estradiol Replacement Improves High-Fat Diet-Induced Obesity by Suppressing the Action of Ghrelin in Ovariectomized Rats.
Autorzy :
Yokota-Nakagi N; Department of Environmental Health, Faculty of Human Life and Environment, Nara Women's University, Kitauoya Nishimachi, Nara 630-8506, Japan.; Department of Health and Nutrition, Faculty of Health Science, Kyoto Koka Women's University, 38 Kadono-cho, Nishikyogoku, Ukyo-ku, Kyoto 615-0882, Japan.
Takahashi H; Department of Environmental Health, Faculty of Human Life and Environment, Nara Women's University, Kitauoya Nishimachi, Nara 630-8506, Japan.
Kawakami M; Department of Environmental Health, Faculty of Human Life and Environment, Nara Women's University, Kitauoya Nishimachi, Nara 630-8506, Japan.
Takamata A; Department of Environmental Health, Faculty of Human Life and Environment, Nara Women's University, Kitauoya Nishimachi, Nara 630-8506, Japan.
Uchida Y; Department of Environmental Health, Faculty of Human Life and Environment, Nara Women's University, Kitauoya Nishimachi, Nara 630-8506, Japan.
Morimoto K; Department of Environmental Health, Faculty of Human Life and Environment, Nara Women's University, Kitauoya Nishimachi, Nara 630-8506, Japan.
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Źródło :
Nutrients [Nutrients] 2020 Mar 26; Vol. 12 (4). Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Diet, High-Fat*
Estradiol*/administration & dosage
Estradiol*/pharmacology
Ghrelin*/antagonists & inhibitors
Ghrelin*/metabolism
Ovariectomy*
Obesity/*metabolism
Adipose Tissue/drug effects ; Animals ; Energy Intake/drug effects ; Female ; Oligopeptides/administration & dosage ; Oligopeptides/pharmacology ; Rats ; Rats, Wistar ; Receptors, Ghrelin/agonists
Czasopismo naukowe
Tytuł :
Ghrelin antagonist overrides the mRNA expression of NPY in hypothalamus in feed restricted ewes.
Autorzy :
Martin ACC; Department of Animal Sciences, The Ohio State University, Wooster, OH, United States of America.; IGEVET-Instituto de Genética Veterinaria Prof. Fernando N. Dulout (UNLP-CONICET), Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina.
Parker AJ; Department of Animal Sciences, The Ohio State University, Wooster, OH, United States of America.
Furnus CC; IGEVET-Instituto de Genética Veterinaria Prof. Fernando N. Dulout (UNLP-CONICET), Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina.
Relling AE; Department of Animal Sciences, The Ohio State University, Wooster, OH, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Sep 09; Vol. 15 (9), pp. e0238465. Date of Electronic Publication: 2020 Sep 09 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Ghrelin/*metabolism
Oligopeptides/*pharmacology
Reproduction/*drug effects
Animals ; Body Weight ; Female ; Ghrelin/antagonists & inhibitors ; Growth Hormone/metabolism ; Growth Hormone-Releasing Hormone/metabolism ; Hypothalamus/metabolism ; Neuropeptide Y/metabolism ; Oligopeptides/metabolism ; RNA, Messenger/metabolism ; Receptors, Ghrelin/metabolism ; Sheep/genetics
Czasopismo naukowe
Tytuł :
Ghrelin signaling contributes to fasting-induced attenuation of hindbrain neural activation and hypophagic responses to systemic cholecystokinin in rats.
Autorzy :
Maniscalco JW; Department of Psychology and Neuroscience, Regis University, Denver, Colorado.
Edwards CM; Department of Psychology and Program in Neuroscience, Florida State University, Tallahassee, Florida.
Rinaman L; Department of Psychology and Program in Neuroscience, Florida State University, Tallahassee, Florida.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2020 May 01; Vol. 318 (5), pp. R1014-R1023. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Appetite Regulation/*drug effects
Cholecystokinin/*administration & dosage
Eating/*drug effects
Fasting/*metabolism
Feeding Behavior/*drug effects
Ghrelin/*blood
Neurons/*drug effects
Rhombencephalon/*drug effects
Animals ; Glucagon-Like Peptide 1/metabolism ; Leptin/blood ; Male ; Neurons/metabolism ; Prolactin-Releasing Hormone/metabolism ; Proto-Oncogene Proteins c-fos/metabolism ; Rats, Sprague-Dawley ; Receptors, Ghrelin/metabolism ; Rhombencephalon/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
A new understanding of GHSR1a--independent of ghrelin activation.
Autorzy :
Xiao X; Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, China.
Bi M; Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, China.
Jiao Q; Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, China.
Chen X; Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, China.
Du X; Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, China. Electronic address: .
Jiang H; Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, China. Electronic address: .
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Źródło :
Ageing research reviews [Ageing Res Rev] 2020 Dec; Vol. 64, pp. 101187. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Ghrelin*
Receptors, Ghrelin*
Humans
Czasopismo naukowe
Tytuł :
Serum nesfatin-1, ghrelin, and lipid levels in adolescents with first episode drug naïve unipolar depression.
Autorzy :
Karadeniz S; Department of Child and Adolescent Psychiatry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Yaman H; Department of Medical Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Bilginer Ç; Department of Child and Adolescent Psychiatry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Hızarcı Bulut S; Department of Child and Adolescent Psychiatry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Yaman SÖ; Department of Medical Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
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Źródło :
Nordic journal of psychiatry [Nord J Psychiatry] 2020 Nov; Vol. 74 (8), pp. 613-619. Date of Electronic Publication: 2020 Jun 04.
Typ publikacji :
Journal Article
MeSH Terms :
Depressive Disorder, Major*/diagnosis
Ghrelin*
Adolescent ; Anxiety Disorders ; Child ; Humans ; Lipids ; Mood Disorders
Czasopismo naukowe
Tytuł :
Hemostatic effect of acylated ghrelin in control and sleeve gastrectomy-induced rats: mechanisms of action.
Autorzy :
Morsy MD; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, College of Medicine, Menoufia University, Shebeen Alkoom, Egypt.
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Źródło :
Archives of physiology and biochemistry [Arch Physiol Biochem] 2020 Feb; Vol. 126 (1), pp. 31-40. Date of Electronic Publication: 2018 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Aorta/*drug effects
Blood Coagulation/*drug effects
Endothelial Cells/*drug effects
Gastrectomy/*methods
Ghrelin/*pharmacology
Hemostatics/*pharmacology
Acylation ; Angiotensin II/pharmacology ; Animals ; Aorta/cytology ; Aorta/metabolism ; Drug Administration Schedule ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Fibrinogen/metabolism ; Gene Expression/drug effects ; Ghrelin/analogs & derivatives ; Injections, Subcutaneous ; Male ; NG-Nitroarginine Methyl Ester/pharmacology ; Nitric Oxide/antagonists & inhibitors ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type III/metabolism ; Oligopeptides/pharmacology ; Plasminogen Activator Inhibitor 1/genetics ; Plasminogen Activator Inhibitor 1/metabolism ; Platelet Aggregation/drug effects ; Primary Cell Culture ; Rats ; Rats, Sprague-Dawley ; Receptors, Ghrelin/antagonists & inhibitors ; Receptors, Ghrelin/genetics ; Receptors, Ghrelin/metabolism ; Thromboxane B2/metabolism ; von Willebrand Factor/metabolism
Czasopismo naukowe
Tytuł :
A systematic review and meta-analysis of medium-chain triglycerides effects on acute satiety and food intake.
Autorzy :
Maher T; Diet and Cardiometabolic Health Research Group, Department of Nutritional Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom of Great Britain and Northern Ireland.; Oxford Brookes Centre for Nutrition and Health, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, United Kingdom of Great Britain and Northern Ireland.
Clegg ME; Department of Food and Nutritional Sciences, University of Reading, Reading, United Kingdom of Great Britain and Northern Ireland.
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Źródło :
Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2021; Vol. 61 (4), pp. 636-648. Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Ghrelin*
Satiation*
Appetite ; Eating ; Energy Intake ; Humans ; Prospective Studies ; Triglycerides
Czasopismo naukowe
Tytuł :
Acyl-ghrelin Is Permissive for the Normal Counterregulatory Response to Insulin-Induced Hypoglycemia.
Autorzy :
Shankar K; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.
Gupta D; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.
Mani BK; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.
Findley BG; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.
Lord CC; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.
Osborne-Lawrence S; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.
Metzger NP; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.
Pietra C; Helsinn Healthcare SA, Lugano, Switzerland.
Liu C; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.; Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX.
Berglund ED; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX .
Zigman JM; Center for Hypothalamic Research, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX .; Division of Endocrinology, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.; Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX.
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Źródło :
Diabetes [Diabetes] 2020 Feb; Vol. 69 (2), pp. 228-237. Date of Electronic Publication: 2019 Nov 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ghrelin/*metabolism
Hypoglycemia/*chemically induced
Insulin/*toxicity
Animals ; Ghrelin/genetics ; Glucose Clamp Technique ; Hypoglycemia/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neuroprotective Agents/pharmacology ; Piperidines/pharmacology ; Receptors, Ghrelin/agonists
Czasopismo naukowe
Tytuł :
The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: preclinical safety experiments and a phase 1b human laboratory study.
Autorzy :
Lee MR; Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.
Tapocik JD; Section on Molecular Pathophysiology, Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Ghareeb M; Clinical Pharmacokinetics Research Laboratory, Department of Biomedical & Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI, USA.
Schwandt ML; Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Dias AA; Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.
Le AN; Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.
Cobbina E; Clinical Pharmacokinetics Research Laboratory, Department of Biomedical & Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI, USA.
Farinelli LA; Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.
Bouhlal S; Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.
Farokhnia M; Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.
Heilig M; Section on Molecular Pathophysiology, Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.; Center for Social and Affective Neuroscience, Linköping University, Linköping, Sweden.
Akhlaghi F; Clinical Pharmacokinetics Research Laboratory, Department of Biomedical & Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI, USA.
Leggio L; Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA. .; Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University, Providence, RI, USA. .
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Źródło :
Molecular psychiatry [Mol Psychiatry] 2020 Feb; Vol. 25 (2), pp. 461-475. Date of Electronic Publication: 2018 May 04.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alcoholic Intoxication/*drug therapy
Azetidines/*pharmacology
Receptors, Ghrelin/*agonists
Spiro Compounds/*pharmacology
Adult ; Alcohol Drinking/drug therapy ; Alcohol Drinking/metabolism ; Alcoholism/drug therapy ; Alcoholism/metabolism ; Animals ; Azetidines/metabolism ; Azetidines/pharmacokinetics ; Ethanol/chemistry ; Female ; Ghrelin/metabolism ; Humans ; Male ; Middle Aged ; Rats ; Rats, Wistar ; Receptors, Ghrelin/metabolism ; Research Design ; Single-Blind Method ; Spiro Compounds/metabolism ; Spiro Compounds/pharmacokinetics
Czasopismo naukowe
Tytuł :
Ghrelin reverses ductular reaction and hepatic fibrosis in a rodent model of cholestasis.
Autorzy :
Petrescu AD; Central Texas Veterans Health Care System, Temple, TX, 76504, USA.; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA.
Grant S; Central Texas Veterans Health Care System, Temple, TX, 76504, USA.; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA.
Williams E; Central Texas Veterans Health Care System, Temple, TX, 76504, USA.; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA.
Frampton G; Department of Internal Medicine, Dell Medical School, The University of Texas at Austin, Austin, TX, 78701, USA.
Reinhart EH; Department of Internal Medicine, Baylor Scott & White Health, Temple, TX, 76502, USA.
Nguyen A; University of Mary Hardin-Baylor, Belton, TX, 76513, USA.
An S; Central Texas Veterans Health Care System, Temple, TX, 76504, USA.; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA.
McMillin M; Central Texas Veterans Health Care System, Temple, TX, 76504, USA.; Department of Internal Medicine, Dell Medical School, The University of Texas at Austin, Austin, TX, 78701, USA.
DeMorrow S; Central Texas Veterans Health Care System, Temple, TX, 76504, USA. .; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA. .; Department of Internal Medicine, Dell Medical School, The University of Texas at Austin, Austin, TX, 78701, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 29; Vol. 10 (1), pp. 16024. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cholestasis/*drug therapy
Ghrelin/*administration & dosage
Liver Cirrhosis/*prevention & control
Receptors, Ghrelin/*genetics
ATP Binding Cassette Transporter, Subfamily B/genetics ; Acetyltransferases/metabolism ; Animals ; Cell Proliferation/drug effects ; Cells, Cultured ; Cholestasis/genetics ; Cholestasis/metabolism ; Disease Models, Animal ; Forkhead Box Protein O1/metabolism ; Ghrelin/metabolism ; Ghrelin/pharmacology ; Liver Cirrhosis/genetics ; Liver Cirrhosis/metabolism ; Mice ; Mice, Knockout ; Transaminases/blood
Czasopismo naukowe
Tytuł :
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.
Autorzy :
Shiimura Y; Division of Molecular Genetics, Institute of Life Science, Kurume University, Fukuoka, Japan.; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Horita S; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hamamoto A; Division of Molecular Genetics, Institute of Life Science, Kurume University, Fukuoka, Japan.
Asada H; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hirata K; RIKEN, SPring-8 Center, Hyogo, Japan.; Japan Science and Technology Agency (JST), Precursory Research for Embryonic Science and Technology (PRESTO), Saitama, Japan.
Tanaka M; Division of Molecular Genetics, Institute of Life Science, Kurume University, Fukuoka, Japan.
Mori K; Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan.
Uemura T; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kobayashi T; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Iwata S; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. .; Japan Science and Technology Agency (JST), Precursory Research for Embryonic Science and Technology (PRESTO), Saitama, Japan. .
Kojima M; Division of Molecular Genetics, Institute of Life Science, Kurume University, Fukuoka, Japan. .
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Źródło :
Nature communications [Nat Commun] 2020 Aug 19; Vol. 11 (1), pp. 4160. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ghrelin/*metabolism
Phenylalanine/*metabolism
Receptors, Ghrelin/*metabolism
Animals ; Binding Sites/genetics ; CHO Cells ; Cricetinae ; Cricetulus ; Crystallography, X-Ray ; Ghrelin/chemistry ; Ghrelin/genetics ; HEK293 Cells ; Humans ; Ligands ; Mice, Inbred MRL lpr ; Mutagenesis, Site-Directed ; Phenylalanine/chemistry ; Phenylalanine/genetics ; Protein Binding ; Protein Conformation ; Receptors, Ghrelin/antagonists & inhibitors ; Receptors, Ghrelin/genetics ; Sf9 Cells ; Spodoptera
Czasopismo naukowe
Tytuł :
Effects of disrupted ghrelin receptor function on fear processing, anxiety and saccharin preference in mice.
Autorzy :
Pierre A; Department of Pharmaceutical Sciences, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
Regin Y; Department of Pharmaceutical Sciences, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
Van Schuerbeek A; Department of Pharmaceutical Sciences, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
Fritz EM; Department of Pharmacology and Toxicology, Institute of Pharmacy and CMBI, University of Innsbruck, Innrain 80/82, Innsbruck, Austria.
Muylle K; Department of Pharmaceutical Sciences, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
Beckers T; Departement of Psychology and Leuven Brain Institute, KU Leuven, Tiensestraat 102 box 3712, 3000, Leuven, Belgium.
Smolders IJ; Department of Pharmaceutical Sciences, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
Singewald N; Department of Pharmacology and Toxicology, Institute of Pharmacy and CMBI, University of Innsbruck, Innrain 80/82, Innsbruck, Austria.
De Bundel D; Department of Pharmaceutical Sciences, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address: .
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Źródło :
Psychoneuroendocrinology [Psychoneuroendocrinology] 2019 Dec; Vol. 110, pp. 104430. Date of Electronic Publication: 2019 Sep 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fear*/psychology
Food Preferences*/psychology
Anxiety/*genetics
Receptors, Ghrelin/*genetics
Saccharin/*administration & dosage
Animals ; Anxiety/metabolism ; Anxiety/physiopathology ; Conditioning, Psychological/drug effects ; Conditioning, Psychological/physiology ; Gene Deletion ; Ghrelin/physiology ; Hyperphagia/genetics ; Hyperphagia/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Ghrelin/physiology
Czasopismo naukowe
Tytuł :
Voluntary exercise is motivated by ghrelin, possibly related to the central reward circuit.
Autorzy :
Mifune H; Institute of Animal Experimentation, Kurume University School of Medicine, Kurume, Japan.
Tajiri Y; Division of Endocrinology and Metabolism, Kurume University School of Medicine, Kurume, Japan.
Sakai Y; Institute of Animal Experimentation, Kurume University School of Medicine, Kurume, Japan.
Kawahara Y; Department of Pharmacology, Kurume University School of Medicine, Kurume, Japan.
Hara K; Division of Endocrinology and Metabolism, Kurume University School of Medicine, Kurume, Japan.
Sato T; Molecular Genetics, Life Science Institute, Kurume University, Kurume, Japan.
Nishi Y; Department of Physiology, Kurume University School of Medicine, Kurume, Japan.
Nishi A; Department of Pharmacology, Kurume University School of Medicine, Kurume, Japan.
Mitsuzono R; Department of Exercise Physiology, Institute of Health and Sports Science, Kurume University, Kurume, Japan.
Kakuma T; Bostatistics Center, Kurume University, Kurume, Japan.
Kojima M; Molecular Genetics, Life Science Institute, Kurume University, Kurume, Japan.
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Źródło :
The Journal of endocrinology [J Endocrinol] 2020 Jan 01; Vol. 244 (1), pp. 123-132.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Reward*
Ghrelin/*blood
Motivation/*physiology
Motor Activity/*physiology
Obesity/*blood
Animals ; Disease Models, Animal ; Dopamine/metabolism ; Feeding Behavior/physiology ; Obesity/psychology ; Rats ; Receptors, Ghrelin/agonists
Czasopismo naukowe
Tytuł :
Early Detection of Growth Hormone Secretagogue Receptor Antagonists Exploiting Their Atypical Behavior in Competitive Assays.
Autorzy :
Danila GM; Laboratory for Quality Control and Process Monitoring , University of Bucharest , 030018 Bucharest , Romania.; Romanian Doping Control Laboratory , 022103 Bucharest , Romania.
Puiu M; Laboratory for Quality Control and Process Monitoring , University of Bucharest , 030018 Bucharest , Romania.
Zamfir LG; Laboratory for Quality Control and Process Monitoring , University of Bucharest , 030018 Bucharest , Romania.; ICUB , University of Bucharest , 050107 Bucharest , Romania.
Bala C; Laboratory for Quality Control and Process Monitoring , University of Bucharest , 030018 Bucharest , Romania.; Department of Analytical Chemistry , University of Bucharest , 030018 Bucharest , Romania.
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Źródło :
Analytical chemistry [Anal Chem] 2019 Dec 03; Vol. 91 (23), pp. 14812-14817. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Electrochemical Techniques*
Appetite Depressants/*urine
Benzazepines/*urine
Oligopeptides/*urine
Piperidines/*urine
Quinazolinones/*urine
Receptors, Ghrelin/*metabolism
Tetrazoles/*urine
Antibodies/chemistry ; Binding, Competitive ; Biotin/chemistry ; Doping in Sports ; Ghrelin/chemistry ; Ghrelin/metabolism ; Humans ; Protein Binding ; Receptors, Ghrelin/chemistry ; Streptavidin/chemistry
Czasopismo naukowe
Tytuł :
Acylated and unacylated ghrelin directly regulate ß-3 stimulated lipid turnover in rodent subcutaneous and visceral adipose tissue ex vivo but not in vivo.
Autorzy :
Cervone DT; a Department of Human Health and Nutritional Sciences , University of Guelph , Guelph , Ontario , Canada.
Sheremeta J; a Department of Human Health and Nutritional Sciences , University of Guelph , Guelph , Ontario , Canada.
Kraft EN; a Department of Human Health and Nutritional Sciences , University of Guelph , Guelph , Ontario , Canada.
Dyck DJ; a Department of Human Health and Nutritional Sciences , University of Guelph , Guelph , Ontario , Canada.
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Źródło :
Adipocyte [Adipocyte] 2019 Dec; Vol. 8 (1), pp. 1-15. Date of Electronic Publication: 2018 Oct 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue/*metabolism
Ghrelin/*metabolism
Lipolysis/*physiology
Acylation/physiology ; Adrenergic beta-3 Receptor Agonists/pharmacology ; Animals ; Appetite ; Dioxoles/pharmacology ; Fatty Acids/metabolism ; Ghrelin/physiology ; Growth Hormone/metabolism ; Intra-Abdominal Fat/metabolism ; Lipid Metabolism/physiology ; Lipids/physiology ; Male ; Obesity/metabolism ; Orphan Nuclear Receptors/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, Adrenergic, beta-3/metabolism ; Receptors, Ghrelin ; Subcutaneous Fat/metabolism ; Ultradian Rhythm
Czasopismo naukowe
Tytuł :
Short-chain fatty acids and microbiota metabolites attenuate ghrelin receptor signaling.
Autorzy :
Torres-Fuentes C; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.
Golubeva AV; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.
Zhdanov AV; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
Wallace S; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.
Arboleya S; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.; Teagasc Food Research Centre, Cork, Ireland.
Papkovsky DB; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
El Aidy S; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.
Ross P; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.
Roy BL; Cremo SA, Fribourg, Switzerland; and.
Stanton C; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.; Teagasc Food Research Centre, Cork, Ireland.
Dinan TG; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
Cryan JF; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.
Schellekens H; Alimentary Pharmabiotic Centre (APC) Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 Dec; Vol. 33 (12), pp. 13546-13559. Date of Electronic Publication: 2019 Oct 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastrointestinal Microbiome*
Bacteria/*metabolism
Fatty Acids, Volatile/*pharmacology
Gene Expression Regulation/*drug effects
Lactic Acid/*pharmacology
Receptors, Ghrelin/*metabolism
Ghrelin/pharmacology ; HEK293 Cells ; Humans ; Mitogen-Activated Protein Kinase 1/genetics ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/genetics ; Mitogen-Activated Protein Kinase 3/metabolism ; Receptors, Ghrelin/genetics ; Signal Transduction ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Influence of obestatin on the histological development of the small intestine in piglets during the first week of postnatal life.
Autorzy :
Woliński J; Department of Animal Physiology, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110Jabłonna, Poland.
Szczurek P; Department of Animal Nutrition and Feed Sciences, National Research Institute of Animal Production, Krakowska 1, 32-083Balice, Poland.
Pierzynowska K; Department of Animal Physiology, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110Jabłonna, Poland.; Department of Biology, Lund University, Sölvegatan 35, 223 62Lund, Sweden.; Department of Medical Biology, Institute of Rural Health, Jaczewskiego 2, 20-090Lublin, Poland.
Wychowański P; Department of Dental Surgery, Warsaw Medical University, Nowogrodzka 59, 02-006Warszawa, Poland.
Seklecka B; Early Clinical Trials Unit, University Clinical Centre, Smoluchowskiego 17, 80-214Gdańsk, Poland.; Department of Oncology and Radiotherapy, Medical University of Gdansk, M. Skłodowskiej-Curie 3a, 80-210Gdańsk, Poland.
Boryczka M; Department of Animal Physiology, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110Jabłonna, Poland.
Kuwahara A; Laboratory of Physiology, Institute for Environmental Sciences and Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Shizuoka, 422-8526, Japan.
Kato I; Department of Medical Biochemistry, Kobe Pharmaceutical University, 4-19-1, Motoyama-Kita-Machi, Higashinada-ku, Kobe, 658-8558, Japan.
Drahanchuk O; Department of Animal Physiology, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110Jabłonna, Poland.
Zaworski K; Department of Animal Physiology, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110Jabłonna, Poland.
Pierzynowski SG; Department of Biology, Lund University, Sölvegatan 35, 223 62Lund, Sweden.; Department of Medical Biology, Institute of Rural Health, Jaczewskiego 2, 20-090Lublin, Poland.
Słupecka-Ziemilska M; Department of Human Epigenetics, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106Warszawa, Poland.
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Źródło :
Animal : an international journal of animal bioscience [Animal] 2020 Oct; Vol. 14 (10), pp. 2129-2137. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Ghrelin*
Intestine, Small*
Swine/*growth & development
Animals ; Animals, Newborn ; Duodenum ; Intestinal Mucosa ; Jejunum
Czasopismo naukowe
Tytuł :
Investigation of GHSR methylation levels in thymomas from patients with Myasthenia Gravis.
Autorzy :
Coppedè F; Department of Translational Research and of New Surgical and Medical Technologies, Lab. of Medical Genetics, University of Pisa, Medical School, Via Roma 55, 56126 Pisa, Italy. Electronic address: .
Stoccoro A; Department of Translational Research and of New Surgical and Medical Technologies, Lab. of Medical Genetics, University of Pisa, Medical School, Via Roma 55, 56126 Pisa, Italy.
Nicolì V; Department of Translational Research and of New Surgical and Medical Technologies, Lab. of Medical Genetics, University of Pisa, Medical School, Via Roma 55, 56126 Pisa, Italy.
Gallo R; Department of Translational Research and of New Surgical and Medical Technologies, Lab. of Medical Genetics, University of Pisa, Medical School, Via Roma 55, 56126 Pisa, Italy.
De Rosa A; Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.
Guida M; Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.
Maestri M; Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.
Lucchi M; Division of Thoracic Surgery, Cardiothoracic and Vascular Surgery Department, Pisa University Hospital, Pisa, Italy; Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Ricciardi R; Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy; Division of Thoracic Surgery, Cardiothoracic and Vascular Surgery Department, Pisa University Hospital, Pisa, Italy.
Migliore L; Department of Translational Research and of New Surgical and Medical Technologies, Lab. of Medical Genetics, University of Pisa, Medical School, Via Roma 55, 56126 Pisa, Italy; Department of Laboratory Medicine, Pisa University Hospital, Pisa, Italy.
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Źródło :
Gene [Gene] 2020 Aug 20; Vol. 752, pp. 144774. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Myasthenia Gravis/*genetics
Receptors, Ghrelin/*genetics
Adult ; Aged ; DNA Methylation/genetics ; Female ; Humans ; Lymphocytes/pathology ; Male ; Middle Aged ; Myasthenia Gravis/metabolism ; Neoplasms, Glandular and Epithelial/genetics ; Receptors, Ghrelin/metabolism ; Thymoma/genetics ; Thymus Neoplasms/genetics
SCR Disease Name :
Thymic epithelial tumor
Czasopismo naukowe
Tytuł :
Association of Acyl-Ghrelin With Posttraumatic Stress Disorder in Adolescents Who Experienced Severe Trauma.
Autorzy :
Malik MO; Department of Physiology, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
Shah M; Department of Physiology, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
Irfan Ul Akbar Yousufzai M; Department of Physiology, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
Ullah N; Department of Physiology, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
Burgess JA; Department of Psychiatry, Friedman Brain Institute, Center for Affective Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York.
Goosens KA; Department of Psychiatry, Friedman Brain Institute, Center for Affective Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York.
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Źródło :
JAMA network open [JAMA Netw Open] 2020 Aug 03; Vol. 3 (8), pp. e2013946. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Stress Disorders, Post-Traumatic*/blood
Stress Disorders, Post-Traumatic*/epidemiology
Stress Disorders, Post-Traumatic*/etiology
Ghrelin/*analogs & derivatives
Psychological Trauma/*complications
Adolescent ; Cross-Sectional Studies ; Ghrelin/blood ; Humans
Czasopismo naukowe
Tytuł :
Circulating messenger for neuroprotection induced by molecular hydrogen.
Autorzy :
Noda M; Laboratory of Pathophysiology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
Uemura Y; Laboratory of Pathophysiology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
Yoshii Y; Laboratory of Pathophysiology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
Horita T; Area of Regulatory Biology, Division of Life Science, Graduate School of Science and Engineering, Saitama University, Sakuraku, Saitama 338-8570, Japan.
Takemi S; Area of Regulatory Biology, Division of Life Science, Graduate School of Science and Engineering, Saitama University, Sakuraku, Saitama 338-8570, Japan.
Sakata I; Area of Regulatory Biology, Division of Life Science, Graduate School of Science and Engineering, Saitama University, Sakuraku, Saitama 338-8570, Japan.
Sakai T; Area of Regulatory Biology, Division of Life Science, Graduate School of Science and Engineering, Saitama University, Sakuraku, Saitama 338-8570, Japan.; Area of Life-NanoBio, Division of Strategy Research, Graduate School of Science and Engineering, Saitama University, Sakura-ku, Saitama 338-8570, Japan.
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Źródło :
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2019 Oct; Vol. 97 (10), pp. 909-915. Date of Electronic Publication: 2019 May 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Ghrelin/*metabolism
Hydrogen/*administration & dosage
Neurodegenerative Diseases/*therapy
Neuroprotection/*drug effects
Peripheral Nerve Injuries/*therapy
Animals ; Blood-Brain Barrier/metabolism ; Disease Models, Animal ; Drinking ; Gastric Mucosa/drug effects ; Gastric Mucosa/metabolism ; Ghrelin/blood ; Humans ; Neurodegenerative Diseases/blood ; Oxidative Stress/drug effects ; Peripheral Nerve Injuries/blood ; Receptors, Ghrelin/metabolism ; Signal Transduction/drug effects ; Treatment Outcome ; Water/chemistry
Czasopismo naukowe

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