Integrative analysis of clinical and epigenetic biomarkers of mortality.
Autorzy:
Huan T; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.; Department of Ophthalmology and Visual Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, USA. Nguyen S; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA. Colicino E; Icahn School of Medicine at Mount Sinai, New York, New York, USA. Ochoa-Rosales C; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Centro de Vida Saludable de la Universidad de Concepción, Concepción, Chile. Hill WD; Department of Psychology, Lothian Birth Cohorts, University of Edinburgh, Edinburgh, UK. Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA. Soerensen M; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.; Department of Clinical Biochemistry and Pharmacology, Center for Individualized Medicine in Arterial Diseases, Odense University Hospital, Odense C, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. Zhang Y; Division of Clinical Epidemiology & Aging Research, German Cancer Rsrch Ctr (DKFZ), Heidelberg, Germany. Baldassari A; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA. Elhadad MA; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. Toshiko T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA. Zheng Y; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Domingo-Relloso A; Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institute, Madrid, Spain.; Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.; Department of Statistics and Operations Research, University of Valencia, Valencia, Spain. Lee DH; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA. Ma J; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.; Nutrition Epidemiology and Data Science, Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA. Yao C; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA. Liu C; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA. Hwang SJ; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA. Joehanes R; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA. Fornage M; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA. Bressler J; Department of Internal Medicine, Erasmus, Rotterdam, the Netherlands. van Meurs JBJ; Department of Internal Medicine, Erasmus, Rotterdam, the Netherlands. Debrabant B; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark. Mengel-From J; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. Hjelmborg J; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark. Christensen K; Department of Public Health, Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. Vokonas P; Veterans Affairs, Normative Aging Study, Boston, Massachusetts, USA.; Veterans Affairs, Boston Healthcare System, Boston, Massachusetts, USA.; Boston University School of Public Health, Boston, Massachusetts, USA. Schwartz J; Departments of Environmental Health and Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA. Gahrib SA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.; Department of Psychology, Univ of Edinburgh, Edinburgh, UK. Sotoodehnia N; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA. Sitlani CM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA. Kunze S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. GiegerC; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Neuherberg, Germany.; Institute of Medical Information Sciences, Biometry and Epidemiology, Ludwig-Maximilians-University, Munich, Germany. Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. Deary IJ; Division of Pulmonary, Critical Care and Sleep Medicine, Center for Lung Biology, University of Washington, Seattle, Washington, USA. Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA. Qu Y; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Greenland P; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Lloyd-Jones DM; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Hou L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Bandinelli S; Geriatric Unit, LHATC (Local Health Authorities Tuscany Centre), Florence, Italy. Voortman T; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. Hermann B; Division of Clinical Epidemiology & Aging Research, German Cancer Rsrch Ctr (DKFZ), Heidelberg, Germany.; Network Aging Research (NAR), University of Heidelberg, Heidelberg, Germany. Baccarelli A; Precision Medicine Program, Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA. Whitsel E; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.; Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA. Pankow JS; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA. Levy D; The Framingham Heart Study, Framingham, Massachusetts, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
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Źródło:
Aging cell [Aging Cell] 2022 Jun; Vol. 21 (6), pp. e13608. Date of Electronic Publication: 2022 May 12.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Alcohol consumption is associated with widespread changes in blood DNA methylation: Analysis of cross-sectional and longitudinal data.
Autorzy:
Dugué PA; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. Wilson R; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany. Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK. Jayasekara H; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, Australia. Wang X; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia. Jung CH; Melbourne Bioinformatics, The University of Melbourne, Parkville, VIC, Australia. Joo JE; Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, Australia. Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia. Schmidt DF; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia. Baglietto L; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy. Severi G; CESP, INSERM U1018, Univ. Paris-Sud, UVSQ, Université Paris-Saclay, Gustave Roussy, Villejuif, France. GiegerC; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany. Ladwig KH; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.; Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie des Klinikums Rechts der Isar, Technical University of Munich, Munich, Germany. Peters A; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK. Southey MC; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.; Genetic Epidemiology Laboratory, Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia. English DR; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia. Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. Giles GG; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. Milne RL; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.
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Źródło:
Addiction biology [Addict Biol] 2021 Jan; Vol. 26 (1), pp. e12855. Date of Electronic Publication: 2019 Dec 02.
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