- Tytuł:
- Regulation of hippocampal cGMP levels as a candidate to treat cognitive deficits in Huntington's disease.
- Autorzy:
- Źródło:
- PloS one [PLoS One] 2013 Sep 05; Vol. 8 (9), pp. e73664. Date of Electronic Publication: 2013 Sep 05 (Print Publication: 2013).
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Cognition Disorders/*physiopathology
Cyclic GMP/*metabolism
Hippocampus/*metabolism
Huntington Disease/*physiopathologyMemory /*physiology
Adult ; Aged ; Aged, 80 and over ; Animals ; Anxiety/genetics ; Anxiety/physiopathology ; Anxiety/prevention & control ; Autopsy ; Avoidance Learning/drug effects ; Avoidance Learning/physiology ; Blotting, Western ; Cognition Disorders/genetics ; Cognition Disorders/prevention & control ; Down-Regulation/drug effects ; Female ; Hippocampus/drug effects ; Humans ; Huntington Disease/genetics ; Huntington Disease/prevention & control ; Male ;Memory /drug effects ; Mice ; Mice, Transgenic ; Middle Aged ; Motor Activity/drug effects ; Motor Activity/genetics ; Motor Activity/physiology ; Nitric Oxide Synthase Type I/metabolism ; Phosphodiesterase 5 Inhibitors/pharmacology ; Piperazines/pharmacology ; Purines/pharmacology ; Sildenafil Citrate ; Sulfones/pharmacology
Czasopismo naukowe