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Wyświetlanie 1-2 z 2
Tytuł :
Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons.
Autorzy :
Traube FR; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Özdemir D; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Sahin H; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Scheel C; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Glück AF; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Geserich AS; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Oganesian S; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Kostidis S; Leiden University Medical Center, Center for Proteomics and Metabolomics, Leiden, The Netherlands.
Iwan K; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Rahimoff R; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Giorgio G; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Müller M; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Spada F; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Biel M; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Cox J; Computational Systems Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.
Giera M; Leiden University Medical Center, Center for Proteomics and Metabolomics, Leiden, The Netherlands.
Michalakis S; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany. .; Department of Ophthalmology, University Hospital, LMU Munich, Munich, Germany. .
Carell T; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 02; Vol. 12 (1), pp. 4100. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Nucleus/*enzymology
Cell Nucleus/*metabolism
Dioxygenases/*metabolism
Glutamate Dehydrogenase/*metabolism
Ketoglutaric Acids/*metabolism
Neurons/*metabolism
Animals ; Brain/metabolism ; Citric Acid Cycle ; Dioxygenases/genetics ; Epigenomics ; Gene Expression ; Glutamate Dehydrogenase/genetics ; Glutamic Acid/metabolism ; HEK293 Cells ; Humans ; Ketoglutarate Dehydrogenase Complex/metabolism ; Metabolomics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/metabolism ; Neuronal Plasticity
Czasopismo naukowe
Tytuł :
The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3 -Deficient Mouse Model of Achromatopsia.
Autorzy :
Koch M; Department of Pharmacy-Center for Drug Research, Ludwig-Maximilians-University, 81377 Munich, Germany.
Scheel C; Department of Pharmacy-Center for Drug Research, Ludwig-Maximilians-University, 81377 Munich, Germany.
Ma H; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Yang F; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Stadlmeier M; Department of Chemistry, Ludwig-Maximilians-University, 81377 Munich, Germany.
Glück AF; Department of Chemistry, Ludwig-Maximilians-University, 81377 Munich, Germany.
Murenu E; Department of Pharmacy-Center for Drug Research, Ludwig-Maximilians-University, 81377 Munich, Germany.; Department of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.
Traube FR; Department of Chemistry, Ludwig-Maximilians-University, 81377 Munich, Germany.
Carell T; Department of Chemistry, Ludwig-Maximilians-University, 81377 Munich, Germany.
Biel M; Department of Pharmacy-Center for Drug Research, Ludwig-Maximilians-University, 81377 Munich, Germany.
Ding XQ; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Michalakis S; Department of Pharmacy-Center for Drug Research, Ludwig-Maximilians-University, 81377 Munich, Germany.; Department of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 23; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
Color Vision Defects/*etiology
Color Vision Defects/*metabolism
Cyclic GMP-Dependent Protein Kinase Type II/*metabolism
Cyclic Nucleotide-Gated Cation Channels/*deficiency
Retinal Cone Photoreceptor Cells/*metabolism
Animals ; Biomarkers ; Color Vision Defects/pathology ; Cyclic GMP/metabolism ; Cyclic GMP-Dependent Protein Kinase Type II/genetics ; Disease Models, Animal ; Disease Susceptibility ; Endoplasmic Reticulum Stress ; Fluorescent Antibody Technique ; Gene Expression ; Mice ; Mice, Knockout ; Microscopy, Confocal ; Models, Biological ; Retinal Degeneration/etiology ; Retinal Degeneration/metabolism ; Retinal Degeneration/pathology ; Unfolded Protein Response
Czasopismo naukowe
    Wyświetlanie 1-2 z 2

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