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Tytuł :
The Effect of CYP2C9 Genotype Variants in Type 2 Diabetes on the Pharmacological Effectiveness of Sulfonylureas, Diabetic Retinopathy, and Nephropathy.
Autorzy :
Saberi M; Department of Medical Chemistry, School of Pharmacy, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran.
Ramazani Z; Department of Medical Chemistry, School of Pharmacy, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran.
Rashidi H; Diabetic Research Center, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran.
Saberi A; Department of Medical Genetics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
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Źródło :
Vascular health and risk management [Vasc Health Risk Manag] 2020 Jun 18; Vol. 16, pp. 241-248. Date of Electronic Publication: 2020 Jun 18 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Pharmacogenomic Variants*
Blood Glucose/*drug effects
Cytochrome P-450 CYP2C9/*genetics
Diabetes Mellitus, Type 2/*drug therapy
Diabetic Nephropathies/*genetics
Diabetic Retinopathy/*genetics
Gliclazide/*therapeutic use
Glyburide/*therapeutic use
Hypoglycemic Agents/*therapeutic use
Biomarkers/blood ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/genetics ; Diabetic Nephropathies/diagnosis ; Diabetic Retinopathy/diagnosis ; Female ; Gene Frequency ; Gliclazide/adverse effects ; Gliclazide/blood ; Glyburide/adverse effects ; Glyburide/blood ; Humans ; Hypoglycemia/chemically induced ; Hypoglycemia/genetics ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/blood ; Male ; Middle Aged ; Risk Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Nanocurcumin improved glucose metabolism in streptozotocin-induced diabetic rats: a comparison study with Gliclazide.
Autorzy :
Afifi M; College of Science, Department of Biochemistry, University of Jeddah, Jeddah, Saudi Arabia. .; Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44519, Egypt. .
Alkaladi A; College of Science, Department of Biological Sciences, University of Jeddah, Jeddah, Saudi Arabia.
Abomughaid MM; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, Bisha, 61922, Saudi Arabia.
Abdelazim AM; Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44519, Egypt.
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Jul; Vol. 27 (20), pp. 25271-25277. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental*
Gliclazide*
Animals ; Blood Glucose ; Glucose ; Liver ; Male ; Rats ; Rats, Sprague-Dawley ; Streptozocin
Czasopismo naukowe
Tytuł :
A real-world study in patients with type 2 diabetes mellitus treated with gliclazide modified-release during fasting: DIA-RAMADAN.
Autorzy :
Hassanein M; Department of Endocrinology, Dubai Hospital, Dubai, United Arab Emirates. Electronic address: .
Al Sifri S; Al Hada Military Hospital, Taif, Saudi Arabia.
Shaikh S; Department of Endocrinology, Saifee Hospital, Mumbai, Maharashtra, India.
Abbas Raza S; Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, Pakistan.
Akram J; University of Health Sciences, Lahore, Pakistan.
Pranoto A; Department of Internal Medicine, Faculty of Medicine, Airlangga University/Dr. Soetomo Hospital, Surabaya, Indonesia.
Rudijanto A; Department of Internal Medicine, Faculty of Medicine, Brawijaya University/Dr. Saiful Anwar Hospital, Malang, Indonesia.
Shaltout I; Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.
Fariduddin M; Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Mohd Izani Wan Mohamed W; Department of Medicine, Hospital Universiti Sains Malaysia, Kelantan, Malaysia.
Al Awadi F; Department of Endocrinology, Dubai Hospital, Dubai, United Arab Emirates.
Alessa T; Dasman Diabetes Institute, Kuwait City, Kuwait.
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Corporate Authors :
DIA-RAMADAN study investigators
Źródło :
Diabetes research and clinical practice [Diabetes Res Clin Pract] 2020 May; Vol. 163, pp. 108154. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2/*blood
Fasting/*blood
Gliclazide/*therapeutic use
Hypoglycemic Agents/*therapeutic use
Aged ; Female ; Gliclazide/pharmacology ; Humans ; Hypoglycemic Agents/pharmacology ; Islam ; Male ; Middle Aged ; Prospective Studies
Czasopismo naukowe
Tytuł :
Lipid-Based Gliclazide Nanoparticles for Treatment of Diabetes: Formulation, Pharmacokinetics, Pharmacodynamics and Subacute Toxicity Study.
Autorzy :
Nazief AM; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Hassaan PS; Department of Medical Physiology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Khalifa HM; Department of Histology and Cell Biology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Sokar MS; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
El-Kamel AH; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2020 Feb 18; Vol. 15, pp. 1129-1148. Date of Electronic Publication: 2020 Feb 18 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Gliclazide/*pharmacokinetics
Hypoglycemic Agents/*pharmacokinetics
Nanoparticles/*administration & dosage
Administration, Oral ; Animals ; Biological Availability ; Diabetes Mellitus, Experimental/drug therapy ; Drug Liberation ; Fatty Acids/chemistry ; Freeze Drying ; Gliclazide/administration & dosage ; Gliclazide/toxicity ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/toxicity ; Lipids/chemistry ; Male ; Nanoparticles/chemistry ; Particle Size ; Poloxamer/chemistry ; Rats, Wistar ; Solubility ; Tablets/chemistry ; Toxicity Tests, Subacute
Czasopismo naukowe
Tytuł :
Studies of binding by sulfonylureas with glyoxal- and methylglyoxal-modified albumin by immunoextraction using affinity microcolumns.
Autorzy :
Rodriguez EL; Department of Chemistry, University of Nebraska, Lincoln, NE, 68588-0304, USA.
Tao P; Department of Chemistry, University of Nebraska, Lincoln, NE, 68588-0304, USA.
Woolfork AG; Department of Chemistry, University of Nebraska, Lincoln, NE, 68588-0304, USA.
Li Z; Department of Chemistry, University of Nebraska, Lincoln, NE, 68588-0304, USA.
Matsuda R; Department of Chemistry, University of Nebraska, Lincoln, NE, 68588-0304, USA.
Sun Z; Department of Chemistry, University of Nebraska, Lincoln, NE, 68588-0304, USA.
Hage DS; Department of Chemistry, University of Nebraska, Lincoln, NE, 68588-0304, USA. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Feb 08; Vol. 1638, pp. 461683. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies/*isolation & purification
Chromatography, Affinity/*methods
Glyoxal/*chemistry
Pyruvaldehyde/*chemistry
Serum Albumin, Human/*metabolism
Sulfonylurea Compounds/*chemistry
Adsorption ; Drug Interactions ; Gliclazide/chemistry ; Glyburide ; Glycation End Products, Advanced/metabolism ; Glycosylation ; Humans ; Kinetics ; Protein Binding ; Protein Stability ; Serum Albumin, Human/chemistry ; Warfarin/chemistry
Czasopismo naukowe
Tytuł :
Optimization of gliclazide loaded alginate-gelatin beads employing central composite design.
Autorzy :
Elsayed EW; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Giza, Egypt.
El-Ashmawy AA; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Giza, Egypt.
Mursi NM; Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Emara LH; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Giza, Egypt.
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Źródło :
Drug development and industrial pharmacy [Drug Dev Ind Pharm] 2019 Dec; Vol. 45 (12), pp. 1959-1972. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji :
Journal Article
MeSH Terms :
Chemistry, Pharmaceutical/*methods
Drug Carriers/*chemistry
Gliclazide/*pharmacokinetics
Alginates/chemistry ; Calorimetry, Differential Scanning ; Cross-Linking Reagents/chemistry ; Drug Liberation ; Gelatin/chemistry ; Gliclazide/administration & dosage ; Hydrogen-Ion Concentration ; Models, Chemical ; Particle Size ; Research Design ; Solubility ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Tytuł :
Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model.
Autorzy :
Panda BP; Department of Pharmaceutical Technology, School of Pharmacy, Taylor's University, Lakeside Campus, No 1, Jalan Taylor's, 47500, Subang Jaya, Selangor, Malaysia. .
Krishnamoorthy R; Department of Pharmaceutical Technology, School of Pharmacy, Taylor's University, Lakeside Campus, No 1, Jalan Taylor's, 47500, Subang Jaya, Selangor, Malaysia.
Bhattamisra SK; Department of Life Sciences, School of Pharmacy, International Medical University, Kuala Lumpur, 57000, Malaysia. .
Shivashekaregowda NKH; School of Pharmacy, Taylor's University, Lakeside Campus, No 1, Jalan Taylor's, 47500, Subang Jaya, Selangor, Malaysia.
Seng LB; School of Medicine, Taylor's University, Lakeside Campus, No 1, Jalan Taylor's, 47500, Subang Jaya, Selangor, Malaysia.
Patnaik S; University College of Pharmaceutical Sciences, Kakatiya University, Warangal, Telangana, India.
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Źródło :
Scientific reports [Sci Rep] 2019 Nov 22; Vol. 9 (1), pp. 17331. Date of Electronic Publication: 2019 Nov 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Experimental/*drug therapy
Diabetes Mellitus, Type 2/*drug therapy
Gliclazide/*administration & dosage
Hypoglycemic Agents/*administration & dosage
Polylactic Acid-Polyglycolic Acid Copolymer/*chemistry
Animals ; Biological Availability ; Delayed-Action Preparations ; Disease Models, Animal ; Gliclazide/chemistry ; Gliclazide/pharmacokinetics ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/pharmacokinetics ; Male ; Nanoparticles/chemistry ; Niacinamide/adverse effects ; Particle Size ; Rats ; Streptozocin/adverse effects
Czasopismo naukowe
Tytuł :
Incident Hepatocellular Carcinoma Risk in Patients Treated with a Sulfonylurea: A Nationwide, Nested, Case-Control Study.
Autorzy :
Lee JY; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jang SY; Department of Preventive Medicine, Eulgi University College of Medicine, Daejeon, Republic of Korea.
Nam CM; Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. .
Kang ES; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2019 Jun 12; Vol. 9 (1), pp. 8532. Date of Electronic Publication: 2019 Jun 12.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Carcinoma, Hepatocellular*/chemically induced
Carcinoma, Hepatocellular*/epidemiology
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/epidemiology
Gliclazide*/administration & dosage
Gliclazide*/adverse effects
Liver Neoplasms*/chemically induced
Liver Neoplasms*/epidemiology
Sulfonylurea Compounds*/administration & dosage
Sulfonylurea Compounds*/adverse effects
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Republic of Korea/epidemiology ; Risk Factors
Czasopismo naukowe
Tytuł :
Antidiabetic effect of mangiferin in combination with oral hypoglycemic agents metformin and gliclazide.
Autorzy :
Sekar V; Natural Products Research Laboratory, Department of Biotechnology, School of Life Sciences, Pondicherry University, Puducherry 605014, India.
Mani S; Natural Products Research Laboratory, Department of Biotechnology, School of Life Sciences, Pondicherry University, Puducherry 605014, India.
Malarvizhi R; Natural Products Research Laboratory, Department of Biotechnology, School of Life Sciences, Pondicherry University, Puducherry 605014, India.
Nithya P; Natural Products Research Laboratory, Department of Biotechnology, School of Life Sciences, Pondicherry University, Puducherry 605014, India.
Vasanthi HR; Natural Products Research Laboratory, Department of Biotechnology, School of Life Sciences, Pondicherry University, Puducherry 605014, India. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2019 Jun; Vol. 59, pp. 152901. Date of Electronic Publication: 2019 Mar 22.
Typ publikacji :
Journal Article
MeSH Terms :
Gliclazide/*pharmacology
Hypoglycemic Agents/*pharmacology
Metformin/*pharmacology
Xanthones/*pharmacology
Administration, Oral ; Animals ; Diabetes Mellitus, Experimental/drug therapy ; Drug Therapy, Combination ; Enzymes/genetics ; Enzymes/metabolism ; Gene Expression Regulation/drug effects ; Gliclazide/administration & dosage ; Hep G2 Cells ; Humans ; Insulin/metabolism ; Liver/drug effects ; Liver/metabolism ; Male ; Metformin/administration & dosage ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
SARS-CoV-2 E protein is a potential ion channel that can be inhibited by Gliclazide and Memantine.
Autorzy :
Singh Tomar PP; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus Givat-Ram, Jerusalem, 91904, Israel.
Arkin IT; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus Givat-Ram, Jerusalem, 91904, Israel. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Sep 10; Vol. 530 (1), pp. 10-14. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*pharmacology
Betacoronavirus/*drug effects
Gliclazide/*pharmacology
Ion Channels/*antagonists & inhibitors
Memantine/*pharmacology
Viral Envelope Proteins/*antagonists & inhibitors
Betacoronavirus/metabolism ; COVID-19 ; Coronavirus Envelope Proteins ; Coronavirus Infections/drug therapy ; Coronavirus Infections/virology ; Drug Discovery ; Drug Repositioning ; Humans ; Ion Channels/metabolism ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Viral Envelope Proteins/metabolism
Czasopismo naukowe
Tytuł :
Bioequivalence of Two Formulations of Gliclazide in a Randomized Crossover Study in Healthy Caucasian Subjects Under Fasting Conditions.
Autorzy :
Pop DI; Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, University of Medicine and Pharmacy 'Iuliu Haţieganu,', Cluj-Napoca, Romania.; Clinical Pharmacology and Pharmacokinetics Department, Terapia S.A- a Sun Pharma Company, Cluj-Napoca, Romania.
Oroian M; Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, University of Medicine and Pharmacy 'Iuliu Haţieganu,', Cluj-Napoca, Romania.; Clinical Pharmacology and Pharmacokinetics Department, Terapia S.A- a Sun Pharma Company, Cluj-Napoca, Romania.
Bhardwaj S; Clinical Pharmacology and Pharmacokinetics Department, Terapia S.A- a Sun Pharma Company, Cluj-Napoca, Romania.
Marcovici A; Clinical Pharmacology and Pharmacokinetics Department, Terapia S.A- a Sun Pharma Company, Cluj-Napoca, Romania.
Khuroo A; Clinical Pharmacology and Pharmacokinetics Department, Gurugram, India.
Kochhar R; R&D Formulation Development, Gurugram, India.
Vlase L; Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, University of Medicine and Pharmacy 'Iuliu Haţieganu,', Cluj-Napoca, Romania.
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Źródło :
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2019 Jan; Vol. 8 (1), pp. 16-21. Date of Electronic Publication: 2018 Mar 26.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Gliclazide/*pharmacokinetics
Hypoglycemic Agents/*pharmacokinetics
Administration, Oral ; Adult ; Cross-Over Studies ; Drug Compounding ; European Continental Ancestry Group ; Fasting/metabolism ; Female ; Gliclazide/administration & dosage ; Gliclazide/adverse effects ; Gliclazide/blood ; Healthy Volunteers ; Humans ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/blood ; Male ; Tablets ; Therapeutic Equivalency ; Young Adult
Czasopismo naukowe
Tytuł :
In vitro and in vivo delivery of gliclazide loaded mPEG-PCL micelles and its kinetic release and solubility study.
Autorzy :
Danafar H; a Zanjan Pharmaceutical Nanotechnology Research Center, Zanjan University of Medical Sciences , Zanjan , Iran.; b Department of Pharmaceutical Nanotechnology , School of Pharmacy, Zanjan University of Medical Sciences , Zanjan , Iran.
Jaberizadeh H; b Department of Pharmaceutical Nanotechnology , School of Pharmacy, Zanjan University of Medical Sciences , Zanjan , Iran.
Andalib S; c Department of Pharmacology and Toxicology , School of Pharmacy, Zanjan University of Medical Sciences , Zanjan , Iran.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2018 Dec; Vol. 46 (8), pp. 1625-1636. Date of Electronic Publication: 2017 Nov 03.
Typ publikacji :
Journal Article
MeSH Terms :
Gliclazide*/pharmacokinetics
Gliclazide*/pharmacology
Diabetes Mellitus, Experimental/*drug therapy
Animals ; Delayed-Action Preparations/pharmacokinetics ; Delayed-Action Preparations/pharmacology ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Male ; Micelles ; Rats ; Rats, Wistar ; Solubility
Czasopismo naukowe
Tytuł :
Alogliptin and Gliclazide Similarly Increase Circulating Endothelial Progenitor Cells in Type 2 Diabetes Patients.
Autorzy :
Negro R; Division of Endocrinology, 'V. Fazzi' Hospital, Lecce, Italy.
Greco EL; Division of Endocrinology, 'V. Fazzi' Hospital, Lecce, Italy.
Greco G; San Raffaele Hospital, Faculty of Medicine, Milano, Italy.
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Źródło :
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association [Exp Clin Endocrinol Diabetes] 2019 Apr; Vol. 127 (4), pp. 215-219. Date of Electronic Publication: 2018 Mar 20.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Diabetes Mellitus, Type 2/*drug therapy
Endothelial Progenitor Cells/*drug effects
Gliclazide/*pharmacology
Glycated Hemoglobin A/*drug effects
Hypoglycemic Agents/*pharmacology
Piperidines/*pharmacology
Uracil/*analogs & derivatives
Aged ; Female ; Gliclazide/administration & dosage ; Humans ; Hypoglycemic Agents/administration & dosage ; Male ; Middle Aged ; Piperidines/administration & dosage ; Uracil/administration & dosage ; Uracil/pharmacology
Czasopismo naukowe
Tytuł :
Involvement of glucose-regulated protein 78 and spliced X-box binding protein 1 in the protective effect of gliclazide in diabetic nephropathy.
Autorzy :
Zhang YW; Department of Chinese with Western Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China. Electronic address: .
Wang X; Department of Chinese with Western Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China.
Ren X; Department of Chinese with Western Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China.
Zhang M; Department of Chinese with Western Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China.
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Źródło :
Diabetes research and clinical practice [Diabetes Res Clin Pract] 2018 Dec; Vol. 146, pp. 41-47. Date of Electronic Publication: 2017 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*genetics
Diabetic Nephropathies/*genetics
Gliclazide/*therapeutic use
HSP70 Heat-Shock Proteins/*metabolism
Hypoglycemic Agents/*therapeutic use
Membrane Proteins/*metabolism
X-Box Binding Protein 1/*genetics
Animals ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Experimental/pathology ; Diabetic Nephropathies/drug therapy ; Diabetic Nephropathies/pathology ; Disease Models, Animal ; Gliclazide/pharmacology ; Hypoglycemic Agents/pharmacology ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Determination of gliclazide minimum concentration in type 2 diabetes mellitus patients.
Autorzy :
Czyrski A; Department of Physical Pharmacy and Pharmacokinetics, Poznań University of Medical Sciences, 6 Święcickiego Street, 60-781 Poznań, Poland. Electronic address: .
Resztak M; Department of Physical Pharmacy and Pharmacokinetics, Poznań University of Medical Sciences, 6 Święcickiego Street, 60-781 Poznań, Poland.
Hermann T; Department of Physical Pharmacy and Pharmacokinetics, Poznań University of Medical Sciences, 6 Święcickiego Street, 60-781 Poznań, Poland.
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2018 Oct; Vol. 106, pp. 1267-1270. Date of Electronic Publication: 2018 Jul 20.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Glucose/*drug effects
Diabetes Mellitus, Type 2/*drug therapy
Gliclazide/*administration & dosage
Hypoglycemic Agents/*administration & dosage
Administration, Oral ; Aged ; Biomarkers/blood ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/diagnosis ; Drug Dosage Calculations ; Drug Monitoring ; Fasting/blood ; Female ; Gliclazide/blood ; Gliclazide/pharmacokinetics ; Glycated Hemoglobin A ; Humans ; Hypoglycemic Agents/blood ; Hypoglycemic Agents/pharmacokinetics ; Insulin/blood ; Linear Models ; Male ; Medication Adherence ; Middle Aged ; Models, Biological ; Tablets ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Efficacy and safety of replacing sitagliptin with canagliflozin in real-world patients with type 2 diabetes uncontrolled with sitagliptin combined with metformin and/or gliclazide: The SITA-CANA Switch Study.
Autorzy :
Garcia de Lucas MD; Internal medicine, Hospital Costa del Sol, autovia A7, Málaga, E-29030 Marbella, Spain. Electronic address: .
Pérez Belmonte LM; Hospital Regional Universitario (IBIMA), Málaga and CIBER Fisiopatología Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Malaga, Spain.
Suárez Tembra M; Hospital San Rafael, Coruña, Spain.
Olalla Sierra J; Internal medicine, Hospital Costa del Sol, autovia A7, Málaga, E-29030 Marbella, Spain.
Gómez Huelgas R; Hospital Regional Universitario (IBIMA), Málaga and CIBER Fisiopatología Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Malaga, Spain.
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Źródło :
Diabetes & metabolism [Diabetes Metab] 2018 Sep; Vol. 44 (4), pp. 373-375. Date of Electronic Publication: 2018 May 22.
Typ publikacji :
Journal Article; Multicenter Study; Observational Study
MeSH Terms :
Canagliflozin/*therapeutic use
Diabetes Mellitus, Type 2/*drug therapy
Gliclazide/*therapeutic use
Hypoglycemic Agents/*therapeutic use
Metformin/*therapeutic use
Sitagliptin Phosphate/*therapeutic use
Aged ; Blood Glucose/drug effects ; Blood Pressure/drug effects ; Body Weight ; Canagliflozin/adverse effects ; Canagliflozin/pharmacology ; Female ; Gliclazide/adverse effects ; Gliclazide/pharmacology ; Glycated Hemoglobin A/analysis ; Humans ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/pharmacology ; Male ; Metformin/adverse effects ; Metformin/pharmacology ; Middle Aged ; Retrospective Studies ; Sitagliptin Phosphate/adverse effects ; Sitagliptin Phosphate/pharmacology
Czasopismo naukowe
Tytuł :
Gliclazide monotherapy increases risks of all-cause mortality and has similar risk of acute myocardial infarction and stroke with glimepiride monotherapy in Korean type 2 diabetes mellitus.
Autorzy :
Cho EH; Department of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Han K; Department of Biostatistics, The Catholic University of Korea.
Kim B; Department of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea.
Lee DH; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Jul 17; Vol. 99 (29), pp. e21236.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2/*drug therapy
Gliclazide/*adverse effects
Hypoglycemic Agents/*adverse effects
Myocardial Infarction/*chemically induced
Stroke/*chemically induced
Sulfonylurea Compounds/*adverse effects
Adult ; Aged ; Asian Continental Ancestry Group ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Myocardial Infarction/mortality ; Republic of Korea ; Risk Factors ; Stroke/mortality
Czasopismo naukowe
Tytuł :
Positive interaction of mangiferin with selected oral hypoglycemic drugs: a therapeutic strategy to alleviate diabetic nephropathy in experimental rats.
Autorzy :
Sekar V; Natural Products Research Laboratory, Department of Biotechnology, Pondicherry University, R. V. Nagar, Kalapet, Puducherry, 605014, India.
Mani S; Natural Products Research Laboratory, Department of Biotechnology, Pondicherry University, R. V. Nagar, Kalapet, Puducherry, 605014, India.
Malarvizhi R; Natural Products Research Laboratory, Department of Biotechnology, Pondicherry University, R. V. Nagar, Kalapet, Puducherry, 605014, India.
Barathidasan R; Central Inter-Disciplinary Research Facility, Sri Balaji Vidyapeeth, Puducherry, 607 403, India.
Vasanthi HR; Natural Products Research Laboratory, Department of Biotechnology, Pondicherry University, R. V. Nagar, Kalapet, Puducherry, 605014, India. .
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Źródło :
Molecular biology reports [Mol Biol Rep] 2020 Jun; Vol. 47 (6), pp. 4465-4475. Date of Electronic Publication: 2020 May 25.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetic Nephropathies/*drug therapy
Xanthones/*pharmacology
Animals ; Antioxidants/metabolism ; Diabetes Mellitus/drug therapy ; Diabetes Mellitus/metabolism ; Diabetes Mellitus, Experimental/metabolism ; Diabetic Nephropathies/metabolism ; Drug Therapy, Combination/methods ; Gliclazide/pharmacology ; Hypoglycemic Agents/pharmacology ; Kidney/pathology ; Kidney Function Tests/methods ; Male ; Metformin/pharmacology ; NF-kappa B/metabolism ; Oxidative Stress/drug effects ; Rats ; Rats, Sprague-Dawley ; Transforming Growth Factor beta/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Xanthones/metabolism
Czasopismo naukowe
Tytuł :
Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model.
Autorzy :
Araújo AA; Universidade Federal do Rio Grande do Norte, Programa de Pós-Graduação em Ciências Farmacêuticas, Programa de Pós-Graduação em Saúde Pública, Departamento de Biofísica e Farmacologia, Natal, Rio Grande do Norte, Brasil.
Morais HB; Universidade Federal do Rio Grande do Norte, Programa de Pós-Graduação em Saúde Pública, Natal, Rio Grande do Norte, Brasil.
Medeiros CACX; Universidade Federal do Rio Grande do Norte, Programa de Pós-Graduação RENORBIO, Programa de Pós-Graduação em Biologia, Departamento de Biofísica e Farmacologia, Natal, Rio Grande do Norte, Brasil.
Brito GAC; Universidade Federal do Ceará, Programa de Pós-Graduação em Farmacologia, Programa de Pós-Graduação em Morfologia, Departamento de Morfologia, Fortaleza, Ceará, Brasil.
Guedes PMM; Universidade Federal do Rio Grande do Norte, Programa de Pós-Graduação em Biologia Parasitária, Departamento de Microbiologia e Parasitologia, Natal, Rio Grande do Norte, Brasil.
Hiyari S; University of California, School of Dentistry, Section of Periodontics, Los Angeles, California, United States of America.
Pirih FQ; University of California, School of Dentistry, Section of Periodontics, Los Angeles, California, United States of America.
Araújo Júnior RF; Universidade Federal do Rio Grande do Norte, Departamento de Morfologia, Porgrama de Pós-Graduação em Biologia Funcional e Estrutural, Programa de Pós-Graduação em Ciências da Saúde, Natal, Rio Grande do Norte, Brasil.
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Źródło :
Journal of applied oral science : revista FOB [J Appl Oral Sci] 2019 Feb 21; Vol. 27, pp. e20180211. Date of Electronic Publication: 2019 Feb 21.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Alveolar Bone Loss/*drug therapy
Antioxidants/*pharmacology
Gliclazide/*pharmacology
Oxidative Stress/*drug effects
Periodontitis/*drug therapy
Alveolar Bone Loss/pathology ; Animals ; Antioxidants/therapeutic use ; Cathepsin K/analysis ; Fluorescent Antibody Technique ; Gingiva/chemistry ; Gingiva/pathology ; Gliclazide/therapeutic use ; Glutathione/analysis ; Immunohistochemistry ; Interleukin-1beta/analysis ; Macrophage Migration-Inhibitory Factors/drug effects ; Male ; Malondialdehyde/analysis ; Matrix Metalloproteinase 2/analysis ; Neutrophils/drug effects ; Periodontitis/pathology ; Peroxidase/analysis ; RANK Ligand/analysis ; Random Allocation ; Rats, Wistar ; Receptor Activator of Nuclear Factor-kappa B/analysis ; Reproducibility of Results ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Necrosis Factor-alpha/analysis ; X-Ray Microtomography
Czasopismo naukowe

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