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Wyszukujesz frazę ""Glioblastoma"" wg kryterium: Temat


Tytuł :
Knockdown of carbohydrate sulfotransferase 12 decreases the proliferation and mobility of glioblastoma cells via the WNT/β-catenin pathway.
Autorzy :
Wang J; Department of Neurology, Changle People's Hospital, Weifang Shandong, China.
Xia X; Department of Neurology, Changle People's Hospital, Weifang Shandong, China.
Tao X; Department of Neurology, Changle People's Hospital, Weifang Shandong, China.
Zhao P; Department of Oncology, Changle People's Hospital, Weifang Shandong, China.
Deng C; Department of Neurology, Changle People's Hospital, Weifang Shandong, China.
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Źródło :
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 3934-3946.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement*/genetics
Gene Knockdown Techniques*
Wnt Signaling Pathway*
Brain Neoplasms/*enzymology
Brain Neoplasms/*pathology
Glioblastoma/*enzymology
Glioblastoma/*pathology
Sulfotransferases/*deficiency
Brain Neoplasms/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Glioblastoma/genetics ; Humans ; Male ; Middle Aged ; Sulfotransferases/genetics ; Sulfotransferases/metabolism ; Survival Analysis ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Clinicopathological characteristics and treatment outcomes of epithelioid glioblastoma.
Autorzy :
Sun K; Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China.
Zhou X; Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China.
Li T; Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China.
Zuo M; Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China.
Li J; Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China.
Liu Y; Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China. .
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Źródło :
Neurosurgical review [Neurosurg Rev] 2021 Dec; Vol. 44 (6), pp. 3335-3348. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnosis
Brain Neoplasms*/therapy
Glioblastoma*/diagnosis
Glioblastoma*/therapy
Adult ; Female ; Humans ; Male ; Mutation ; Prognosis ; Proto-Oncogene Proteins B-raf/genetics ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Prognostic value of pretreatment circulating basophils in patients with glioblastoma.
Autorzy :
Zheng L; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Gaopeng Street, Keyuan Road 4, Chengdu, 610041, Sichuan, China.
Yu M; Department of Thoracic Oncology, West China Hospital, Sichuan University, Chengdu, China.
Zhang S; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Gaopeng Street, Keyuan Road 4, Chengdu, 610041, Sichuan, China. .
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Źródło :
Neurosurgical review [Neurosurg Rev] 2021 Dec; Vol. 44 (6), pp. 3471-3478. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article
MeSH Terms :
Basophils*
Glioblastoma*/diagnosis
Glioblastoma*/surgery
Humans ; Kaplan-Meier Estimate ; Nomograms ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Identification of imidazo[4,5-c]pyridin-2-one derivatives as novel Src family kinase inhibitors against glioblastoma.
Autorzy :
Zhang L; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Yang Z; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Sang H; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Jiang Y; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Zhou M; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Huang C; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Huang C; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Wu X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Zhang T; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, PR China.
Zhang X; Department of Neurobiology, Guangdong Province Key Laboratory of Psychiatric Disorders, School of Basic Medical Sciences, Southern Medical University, Guangzhou, PR China.
Wan S; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
Zhang J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, PR China.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 1541-1552.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Brain Neoplasms/*drug therapy
Glioblastoma/*drug therapy
Imidazoles/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Quinolones/*pharmacology
src-Family Kinases/*antagonists & inhibitors
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Imidazoles/chemical synthesis ; Imidazoles/chemistry ; Models, Molecular ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Quinolones/chemical synthesis ; Quinolones/chemistry ; Structure-Activity Relationship ; src-Family Kinases/metabolism
Czasopismo naukowe
Tytuł :
A Super-selective Wada Test Successfully Detected an Artery That Supplied Broca's Area in a Case of Left Frontal Lobe Glioblastoma: Technical Case Report.
Autorzy :
Yamashita S; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.
Saito R; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.; Department of Neurosurgical Engineering and Translational Neuroscience, Tohoku University Graduate School of Medicine.
Osawa SI; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.
Niizuma K; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.; Department of Neurosurgical Engineering and Translational Neuroscience, Tohoku University Graduate School of Medicine.; Department of Neurosurgical Engineering and Translational Neuroscience, Graduate School of Biomedical Engineering, Tohoku University.
Ukishiro K; Department of Epileptology, Graduate School of Medicine, Tohoku University.
Kanamori M; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.
Kakinuma K; Department of Behavioral Neurology and Cognitive Neuroscience, Graduate School of Medicine, Tohoku University.
Suzuki K; Department of Behavioral Neurology and Cognitive Neuroscience, Graduate School of Medicine, Tohoku University.
Tominaga T; Department of Neurosurgery, Graduate School of Medicine, Tohoku University.
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Źródło :
Neurologia medico-chirurgica [Neurol Med Chir (Tokyo)] 2021 Nov 15; Vol. 61 (11), pp. 661-666. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/surgery
Glioblastoma*/diagnostic imaging
Glioblastoma*/surgery
Adult ; Brain Mapping ; Broca Area/diagnostic imaging ; Frontal Lobe/diagnostic imaging ; Frontal Lobe/surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Cerebral Artery ; Wakefulness
Czasopismo naukowe
Tytuł :
Perfusion parameters derived from MRI for preoperative prediction of IDH mutation and MGMT promoter methylation status in glioblastomas.
Autorzy :
Lu J; Department of Radiology, The Affiliated Tumor Hospital of Zhengzhou University & Henan Cancer Hospital, China.
Li X; Department of Radiology, The Affiliated Tumor Hospital of Zhengzhou University & Henan Cancer Hospital, China.
Li H; Department of Radiology, The Affiliated Tumor Hospital of Zhengzhou University & Henan Cancer Hospital, China. Electronic address: .
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Źródło :
Magnetic resonance imaging [Magn Reson Imaging] 2021 Nov; Vol. 83, pp. 189-195. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
DNA Modification Methylases*/genetics
DNA Repair Enzymes*/genetics
Glioblastoma*/diagnostic imaging
Glioblastoma*/genetics
Tumor Suppressor Proteins*/genetics
Isocitrate Dehydrogenase/*genetics
Diffusion Magnetic Resonance Imaging ; Humans ; Magnetic Resonance Imaging ; Methylation ; Mutation ; Perfusion ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Correlation between dynamic susceptibility contrast perfusion MRI and genomic alterations in glioblastoma.
Autorzy :
Ozturk K; Department of Radiology, University of Minnesota Health, B-226 Mayo Memorial Building, MMC 292, 420 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Soylu E; Department of Radiology, University of Minnesota Health, B-226 Mayo Memorial Building, MMC 292, 420 Delaware Street S.E., Minneapolis, MN, 55455, USA.
Cayci Z; Department of Radiology, University of Minnesota Health, B-226 Mayo Memorial Building, MMC 292, 420 Delaware Street S.E., Minneapolis, MN, 55455, USA. .
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Źródło :
Neuroradiology [Neuroradiology] 2021 Nov; Vol. 63 (11), pp. 1801-1810. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
Glioblastoma*/diagnostic imaging
Glioblastoma*/genetics
Adult ; Aged ; Aged, 80 and over ; Female ; Genomics ; Humans ; Isocitrate Dehydrogenase/genetics ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Mutation ; Perfusion ; Retrospective Studies ; Young Adult
Czasopismo naukowe
Tytuł :
Long noncoding RNA just proximal to X-inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A-dependent manner in glioblastoma multiforme cells.
Autorzy :
Li XD; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang MJ; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zheng JL; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu YH; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang X; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jiang XB; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło :
Cancer science [Cancer Sci] 2021 Nov; Vol. 112 (11), pp. 4543-4552. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Alkylating/*pharmacology
Brain Neoplasms/*metabolism
Glioblastoma/*metabolism
Pyruvate Dehydrogenase Acetyl-Transferring Kinase/*metabolism
RNA, Long Noncoding/*metabolism
Temozolomide/*pharmacology
Adenosine/analogs & derivatives ; Adenosine/metabolism ; Aerobiosis ; Alpha-Ketoglutarate-Dependent Dioxygenase FTO/metabolism ; Brain Neoplasms/drug therapy ; Brain Neoplasms/mortality ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Demethylation ; Disease Progression ; Drug Resistance, Neoplasm ; Glioblastoma/drug therapy ; Glioblastoma/mortality ; Glioblastoma/pathology ; Glycolysis ; Humans ; Neoplasm Proteins/metabolism ; Prognosis ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Glioblastoma with primitive neuronal component: An immunohistochemical study and review of literature.
Autorzy :
Poyuran R; Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695011, Kerala, India. Electronic address: .
Chandrasekharan K; Department of Imaging Sciences and Intervention Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695011, Kerala, India. Electronic address: .
Easwer HV; Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695011, Kerala, India. Electronic address: .
Narasimhaiah D; Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum 695011, Kerala, India. Electronic address: .
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Źródło :
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2021 Nov; Vol. 93, pp. 130-136. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
Glioblastoma*/diagnostic imaging
Glioblastoma*/genetics
Adult ; Child ; Female ; Humans ; Infant ; Male ; Middle Aged ; Mutation
Czasopismo naukowe
Tytuł :
Chemopreventive effect of spirulina microalgae on an animal model of glioblastoma via down-regulation of PI3K/AKT/mTOR and up-regulation of miR-34a/miR-125B expression.
Autorzy :
Arab S; Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.; Department of Tissue Engineering and Applied Cell Sciences, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Ghasemi S; Student research committee, Semnan University of Medical Sciences, Semnan, Iran.
Ghanbari A; Research center of physiology, Semnan University of Medical Sciences, Semnan, Iran.
Bahraminasab M; Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.; Department of Tissue Engineering and Applied Cell Sciences, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Satari A; Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Mousavi M; Department of Anatomy, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Dehcheshme HG; Student research committee, Semnan University of Medical Sciences, Semnan, Iran.
Asgharzade S; Student research committee, Semnan University of Medical Sciences, Semnan, Iran.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Nov; Vol. 35 (11), pp. 6452-6461. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article
MeSH Terms :
Glioblastoma*/drug therapy
Glioblastoma*/genetics
MicroRNAs*/genetics
Microalgae*
Spirulina*
Animals ; Apoptosis ; Cell Proliferation ; Disease Models, Animal ; Down-Regulation ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Patterns of glioblastoma treatment and survival over a 16-years period: pooled data from the German Cancer Registries.
Autorzy :
Efremov L; Institute for Medical Epidemiology, Biometrics and Informatics (IMEBI), Interdisciplinary Center for Health Sciences, Medical School of the Martin-Luther-University Halle-Wittenberg, Magdeburger Str. 8, 06112, Halle (Saale), Germany.; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany.
Abera SF; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany.
Bedir A; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany.
Vordermark D; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany.
Medenwald D; Institute for Medical Epidemiology, Biometrics and Informatics (IMEBI), Interdisciplinary Center for Health Sciences, Medical School of the Martin-Luther-University Halle-Wittenberg, Magdeburger Str. 8, 06112, Halle (Saale), Germany. .; Department of Radiation Oncology, Martin-Luther-University, Halle (Saale), Germany. .
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Nov; Vol. 147 (11), pp. 3381-3390. Date of Electronic Publication: 2021 Mar 20.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*mortality
Brain Neoplasms/*therapy
Glioblastoma/*mortality
Glioblastoma/*therapy
Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Antineoplastic Agents, Alkylating/administration & dosage ; Brain Neoplasms/drug therapy ; Female ; Germany/epidemiology ; Glioblastoma/drug therapy ; Humans ; Male ; Middle Aged ; Proportional Hazards Models ; Registries ; Survival Rate ; Temozolomide/administration & dosage ; Young Adult
Czasopismo naukowe
Tytuł :
Glioblastoma with deep supratentorial extension is associated with a worse overall survival.
Autorzy :
Barsouk A; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Baldassari MP; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Khanna O; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Andrews CE; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Ye DY; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Velagapudi L; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Al Saiegh F; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Hafazalla K; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Cunningham E; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Patel H; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Malkani K; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Fitchett EM; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Farrell CJ; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Judy KD; Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA. Electronic address: .
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Źródło :
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2021 Nov; Vol. 93, pp. 82-87. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/surgery
Glioblastoma*/diagnostic imaging
Glioblastoma*/surgery
Supratentorial Neoplasms*/diagnostic imaging
Supratentorial Neoplasms*/surgery
Humans ; Prognosis ; Progression-Free Survival ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Versatile metal-phenolic network nanoparticles for multitargeted combination therapy and magnetic resonance tracing in glioblastoma.
Autorzy :
Zhang Y; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Xi K; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Fu X; Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100, China.
Sun H; Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100, China.
Wang H; Radiology Department, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, China.
Yu D; Radiology Department, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, China.
Li Z; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Ma Y; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Liu X; Department of Pediatrics, Qilu Hospital, Shandong University, Jinan, Shandong, 250012, China.
Huang B; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Wang J; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Li G; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Cui J; Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100, China.
Li X; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Ni S; Department of Neurosurgery, Qilu Hospital and Institute of Brain and Brain-Inspired Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2021 Nov; Vol. 278, pp. 121163. Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glioblastoma*/diagnostic imaging
Glioblastoma*/drug therapy
Metal Nanoparticles*
Nanoparticles*
Apoptosis ; Cell Line, Tumor ; Combined Modality Therapy ; Humans ; Magnetic Resonance Spectroscopy
Czasopismo naukowe
Tytuł :
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia.
Autorzy :
Puxeddu M; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Shen H; Department of Urology, Capital Medical University Beijing Friendship Hospital, Beijing, 100050, China.
Bai R; Molecular Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, United States.
Coluccia A; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Bufano M; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Nalli M; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Sebastiani J; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Brancaccio D; Department of Pharmacy, University of Naples'Federico II', Via Domenico Montesano 49, 80131, Naples, Italy.
Da Pozzo E; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 6, I-56126, Pisa, Italy.
Tremolanti C; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 6, I-56126, Pisa, Italy.
Martini C; Department of Pharmacy, University of Pisa, Via Bonanno Pisano 6, I-56126, Pisa, Italy.
Orlando V; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Biagioni S; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy.
Sinicropi MS; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036, Rende, Cosenza, Italy.
Ceramella J; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036, Rende, Cosenza, Italy.
Iacopetta D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036, Rende, Cosenza, Italy.
Coluccia AML; Department of Biological and Environmental Sciences and Technologies, University of Salento, I-73100, Lecce, Italy.
Hamel E; Molecular Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, United States.
Liu T; Department of Biological and Environmental Sciences and Technologies, University of Salento, I-73100, Lecce, Italy; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365 South Xiangyang Road, Shanghai, 200031, China. Electronic address: .
Silvestri R; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy. Electronic address: .
La Regina G; Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113532. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Discovery*
Antineoplastic Agents/*pharmacology
Glioblastoma/*drug therapy
Heterocyclic Compounds/*pharmacology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Methane/*pharmacology
Tubulin Modulators/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Female ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Heterocyclic Compounds/chemical synthesis ; Heterocyclic Compounds/chemistry ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Methane/analogs & derivatives ; Methane/chemistry ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Molecular Structure ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology ; Polymerization/drug effects ; Structure-Activity Relationship ; Tubulin/metabolism ; Tubulin Modulators/chemical synthesis ; Tubulin Modulators/chemistry ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Liquid Biopsy in Glioblastoma Management: From Current Research to Future Perspectives.
Autorzy :
Gatto L; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Franceschi E; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Di Nunno V; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Tosoni A; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
Lodi R; Istituto delle Scienze Neurologiche di Bologna, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Bologna, Italy.
Brandes AA; Department of Medical Oncology, Azienda Unità Sanitaria Locale (USL) of Bologna, Bologna, Italy.
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Źródło :
The oncologist [Oncologist] 2021 Oct; Vol. 26 (10), pp. 865-878. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain Neoplasms*/diagnosis
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Glioblastoma*/diagnosis
Glioblastoma*/genetics
Glioblastoma*/therapy
MicroRNAs*
Biomarkers, Tumor/genetics ; Humans ; Liquid Biopsy ; Prognosis
Czasopismo naukowe
Tytuł :
BET inhibitors repress expression of interferon-stimulated genes and synergize with HDAC inhibitors in glioblastoma.
Autorzy :
Gusyatiner O; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Lausanne, Switzerland.
Bady P; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Bioinformatics Core Facility, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Lausanne, Switzerland.
Pham MDT; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Lei Y; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Park J; Neuroscience Research Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Daniel RT; Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Delorenzi M; Bioinformatics Core Facility, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Oncology, University of Lausanne, Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Lausanne, Switzerland.
Hegi ME; Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Swiss Cancer Center Léman (SCCL), Lausanne, Switzerland.
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Źródło :
Neuro-oncology [Neuro Oncol] 2021 Oct 01; Vol. 23 (10), pp. 1680-1692.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Histone Deacetylase Inhibitors*/pharmacology
Humans ; Interferons ; Nuclear Proteins
Czasopismo naukowe
Tytuł :
The anesthetist's choice of inhalational vs. intravenous anesthetics has no impact on survival of glioblastoma patients.
Autorzy :
Schmoch T; Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany. .; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany. .
Jungk C; Division of Neurosurgical Research, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
Bruckner T; Institute of Medical Biometry and Informatics (IMBI), University of Heidelberg, Heidelberg, Germany.
Haag S; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany.
Zweckberger K; Division of Neurosurgical Research, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
von Deimling A; Department of Neuropathology, University Hospital Heidelberg and Clinical Cooperation Unit (CCU) Neuropathology, DKFZ, Heidelberg, Germany.
Brenner T; Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany.
Unterberg A; Division of Neurosurgical Research, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
Weigand MA; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany.
Uhle F; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany.
Herold-Mende C; Division of Neurosurgical Research, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
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Źródło :
Neurosurgical review [Neurosurg Rev] 2021 Oct; Vol. 44 (5), pp. 2707-2715. Date of Electronic Publication: 2020 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/drug therapy
Brain Neoplasms*/surgery
Glioblastoma*/drug therapy
Glioblastoma*/surgery
Anesthetics, Intravenous ; Anesthetists ; DNA Modification Methylases ; DNA Repair Enzymes ; Humans ; Prognosis ; Retrospective Studies ; Wakefulness
Czasopismo naukowe
Tytuł :
Peritumoral edema status of glioblastoma identifies patients reaching long-term disease control with specific progression patterns after tumor resection and high-dose proton boost.
Autorzy :
Liang HT; Department of Biomedical Engineering, National Taiwan University, Taipei, Taiwan.; Department of Radiation Oncology, National Taiwan University Cancer Center, National Taiwan University Hospital, Taipei, Taiwan.; Division of Radiation Oncology, National Taiwan University Hospital, Taipei, Taiwan.
Mizumoto M; Department of Radiation Oncology, Proton Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan. .
Ishikawa E; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Matsuda M; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Tanaka K; Department of Radiation Oncology, Proton Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Kohzuki H; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Numajiri H; Department of Radiation Oncology, Proton Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Oshiro Y; Department of Radiation Oncology, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki, Japan.
Okumura T; Department of Radiation Oncology, Proton Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Matsumura A; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Sakurai H; Department of Radiation Oncology, Proton Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Dec; Vol. 147 (12), pp. 3503-3516. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Edema/*pathology
Brain Neoplasms/*pathology
Glioblastoma/*pathology
Adult ; Aged ; Aged, 80 and over ; Brain Neoplasms/therapy ; Disease Progression ; Female ; Glioblastoma/therapy ; Humans ; Male ; Middle Aged ; Neurosurgical Procedures ; Proton Therapy ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Efficacy and safety of nivolumab in Japanese patients with first recurrence of glioblastoma: an open-label, non-comparative study.
Autorzy :
Aoki T; Department of Neurosurgery, National Hospital Organization Kyoto Medical Center, 1-1 Fukakusa Mukaihatacho, Fushimi Ward, Kyoto, 612-8555, Japan. .
Kagawa N; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Sugiyama K; Department of Clinical Oncology and Neuro-Oncology Program, Hiroshima University Hospital, Hiroshima, Japan.
Wakabayashi T; Department of Neurosurgery, Nagoya University Hospital, Nagoya, Japan.
Arakawa Y; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yamaguchi S; Department of Neurosurgery, Hokkaido University Hospital, Hokkaido, Japan.
Tanaka S; Department of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.
Ishikawa E; Department of Neurosurgery, University of Tsukuba Hospital, Ibaraki, Japan.
Muragaki Y; Department of Neurosurgery, Tokyo Women's Medical University Hospital, Tokyo, Japan.
Nagane M; Faculty of Medicine, Department of Neurosurgery, Kyorin University, Tokyo, Japan.
Nakada M; Department of Neurosurgery, Kanazawa University Hospital, Kanazawa, Japan.
Suehiro S; Department of Neurosurgery, Ehime University Hospital, Ehime, Japan.
Hata N; Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kuroda J; Department of Neurosurgery, Kumamoto University Hospital, Kumamoto, Japan.
Narita Y; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.
Sonoda Y; Department of Neurosurgery, Yamagata University Hospital, Yamagata, Japan.
Iwadate Y; Department of Neurological Surgery, Chiba University Hospital, Chiba, Japan.
Natsumeda M; Department of Neurosurgery, Niigata University Medical and Dental Hospital, Niigata, Japan.
Nakazato Y; Hidaka Center for Pathologic Diagnosis and Research, Hidaka Hospital, Gunma, Japan.
Minami H; Department Medical Oncology/Hematology, Kobe University, Kobe, Japan.
Hirata Y; Oncology Early Clinical Development Planning, Ono Pharmaceutical Co., Ltd, Osaka, Japan.
Hagihara S; Department of Statistical Analysis, Ono Pharmaceutical Co., Ltd, Osaka, Japan.
Nishikawa R; Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, Saitama, Japan.
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Źródło :
International journal of clinical oncology [Int J Clin Oncol] 2021 Dec; Vol. 26 (12), pp. 2205-2215. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Glioblastoma*/drug therapy
Nivolumab*/adverse effects
Antineoplastic Combined Chemotherapy Protocols ; Bayes Theorem ; Humans ; Japan ; Neoplasm Recurrence, Local/drug therapy
Czasopismo naukowe
Tytuł :
Fenofibrate inhibits hypoxia-inducible factor-1 alpha and carbonic anhydrase expression through activation of AMP-activated protein kinase/HO-1/Sirt1 pathway in glioblastoma cells.
Autorzy :
Lin C; Department of Physiology, School of Medicine, China Medical University, Taichung, Taiwan.
Lai SW; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.
Shen CK; Graduate Institute of Biomedical Science, China Medical University, Taichung, Taiwan.
Chen CW; Institute of New Drug Development, China Medical University, Taichung, Taiwan.
Tsai CF; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.
Liu YS; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.
Lu DY; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.; Department of Photonics and Communication Engineering, Asia University, Taichung, Taiwan.
Huang BR; Department of Neurosurgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.; School of Medicine, Tzu Chi University, Hualien, Taiwan.
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Źródło :
Environmental toxicology [Environ Toxicol] 2021 Dec; Vol. 36 (12), pp. 2551-2561. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article
MeSH Terms :
Carbonic Anhydrases*
Fenofibrate*/pharmacology
Glioblastoma*/genetics
AMP-Activated Protein Kinases/genetics ; Humans ; Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Sirtuin 1
Czasopismo naukowe

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