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Tytuł :
Regulatory T cells promote glioma cell stemness through TGF-β-NF-κB-IL6-STAT3 signaling.
Autorzy :
Liu S; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Zhang C; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.; Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Wang B; Henan University of Chinese Medicine, Zhengzhou, 450052, Henan, China.
Zhang H; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Qin G; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Li C; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Cao L; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Gao Q; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Ping Y; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Zhang K; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Lian J; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Zhao Q; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Wang D; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Zhang Z; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Zhao X; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Yang L; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Huang L; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China.; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Yang B; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Zhang Y; Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, Henan, China. .; Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China. .; Henan Key Laboratory for Tumor Immunology and Biotherapy, Zhengzhou, 450052, Henan, China. .; School of Life Sciences, Zhengzhou University, Zhengzhou, 450052, Henan, China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Sep; Vol. 70 (9), pp. 2601-2616. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Glioma/*immunology
Glioma/*metabolism
Neoplastic Stem Cells/*metabolism
T-Lymphocytes, Regulatory/*immunology
T-Lymphocytes, Regulatory/*metabolism
Animals ; Antibodies, Monoclonal, Humanized/pharmacology ; Biomarkers ; Cell Self Renewal ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Glioma/mortality ; Glioma/pathology ; Humans ; Immunophenotyping ; Interleukin-6/metabolism ; Mice ; NF-kappa B/metabolism ; Prognosis ; STAT3 Transcription Factor ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
Arbutin exerts anticancer activity against rat C6 glioma cells by inducing apoptosis and inhibiting the inflammatory markers and P13/Akt/mTOR cascade.
Autorzy :
Yang Z; Department of Neurosurgery, Xi'an Children's Hospital, Xi'an, Shaanxi, China.
Shi H; Department of Neurosurgery, Xi'an Children's Hospital, Xi'an, Shaanxi, China.
Chinnathambi A; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Salmen SH; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Alharbi SA; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Veeraraghavan VP; Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Surapaneni KM; Department of Biochemistry, Clinical Skills & Simulation, Molecular Virology and Research, Panimalar Medical College Hospital & Research Institute, Chennai, Tamil Nadu, India.
Arulselvan P; Scigen Research and Innovation Pvt. Ltd., Thanjavur, Tamil Nadu, India.
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Źródło :
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Sep; Vol. 35 (9), pp. e22857. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji :
Journal Article
MeSH Terms :
Glioma*/drug therapy
Glioma*/metabolism
Glioma*/pathology
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Arbutin/*pharmacology
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Signal Transduction/*drug effects
TOR Serine-Threonine Kinases/*metabolism
Animals ; Cell Line, Tumor ; Rats
Czasopismo naukowe
Tytuł :
The Long Non-Coding RNA H19 Drives the Proliferation of Diffuse Intrinsic Pontine Glioma with H3K27 Mutation.
Autorzy :
Roig-Carles D; Cancer Research Group, School of Life, Health and Chemical Sciences, The Open University, Milton Keynes MK7 6AA, UK.
Jackson H; Cancer Research Group, School of Life, Health and Chemical Sciences, The Open University, Milton Keynes MK7 6AA, UK.
Loveson KF; School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2UP, UK.
Mackay A; Division of Molecular Pathology, The Institute of Cancer Research, London SW7 3RP, UK.
Mather RL; Cancer Research Group, School of Life, Health and Chemical Sciences, The Open University, Milton Keynes MK7 6AA, UK.
Waters E; Cancer Research Group, School of Life, Health and Chemical Sciences, The Open University, Milton Keynes MK7 6AA, UK.
Manzo M; Institute of Pathology, University Hospital Basel, 4031 Basel, Switzerland.
Alborelli I; Institute of Pathology, University Hospital Basel, 4031 Basel, Switzerland.
Golding J; Cancer Research Group, School of Life, Health and Chemical Sciences, The Open University, Milton Keynes MK7 6AA, UK.
Jones C; Division of Molecular Pathology, The Institute of Cancer Research, London SW7 3RP, UK.
Fillmore HL; School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2UP, UK.
Crea F; Cancer Research Group, School of Life, Health and Chemical Sciences, The Open University, Milton Keynes MK7 6AA, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 25; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation*
Brain Stem Neoplasms/*genetics
Glioma/*genetics
RNA, Long Noncoding/*metabolism
Brain Stem Neoplasms/metabolism ; Brain Stem Neoplasms/pathology ; Cells, Cultured ; Gene Expression Regulation, Neoplastic ; Glioma/metabolism ; Glioma/pathology ; Histones/metabolism ; Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Mutation ; RNA, Long Noncoding/genetics
Czasopismo naukowe
Tytuł :
Intratumor heterogeneity, microenvironment, and mechanisms of drug resistance in glioma recurrence and evolution.
Autorzy :
Bao Z; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.; Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, China.
Wang Y; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.
Wang Q; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.
Fang S; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.
Shan X; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Department of Radiotherapy Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.
Wang J; Divison of Life Science, Department of Chemical and Biological Engineering, Center for Systems Biology and Human Health, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.
Jiang T; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China. .; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China. .; China National Clinical Research Center for Neurological Diseases, Beijing, 100050, China. .; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, 100069, China. .
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Źródło :
Frontiers of medicine [Front Med] 2021 Aug; Vol. 15 (4), pp. 551-561. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain Neoplasms*/drug therapy
Brain Neoplasms*/genetics
Glioblastoma*
Glioma*/drug therapy
Glioma*/genetics
Aged ; Drug Resistance ; Humans ; Mutation ; Neoplasm Recurrence, Local/drug therapy ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Single institution experience in re-irradiation of biopsy-proven diffuse intrinsic pontine gliomas.
Autorzy :
Zamora PL; Department of Radiation Oncology, Wayne State University School of Medicine, Detroit, MI, USA. .
Miller SR; Department of Radiation Oncology, Wayne State University School of Medicine, Detroit, MI, USA.; Division of Radiation Oncology, Karmanos Cancer Institute, Detroit, MI, USA.
Kovoor JJ; Department of Radiation Oncology, Wayne State University School of Medicine, Detroit, MI, USA.
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Źródło :
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery [Childs Nerv Syst] 2021 Aug; Vol. 37 (8), pp. 2539-2543. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Stem Neoplasms*/radiotherapy
Diffuse Intrinsic Pontine Glioma*
Glioma*/radiotherapy
Re-Irradiation*
Biopsy ; Child ; Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Antibody-drug conjugates for H3K27M-mutant diffuse midline gliomas: prospects and challenges.
Autorzy :
Rechberger JS; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA.
A Power E; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Millesi E; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA.
Daniels DJ; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA.; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
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Źródło :
Therapeutic delivery [Ther Deliv] 2021 Aug; Vol. 12 (8), pp. 553-557. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural
MeSH Terms :
Brain Neoplasms*/drug therapy
Brain Neoplasms*/genetics
Glioma*/drug therapy
Glioma*/genetics
Immunoconjugates*
Humans ; Mutation
Raport
Tytuł :
Cystic angiocentric glioma: a case report and literature review.
Autorzy :
Wang Q; Department of Neurosurgery, Wuhan Brain Hospital, No. 5 Huiji Road, Wuhan, 430014, China.
Xiong Y; Department of Neurosurgery, Wuhan Brain Hospital, No. 5 Huiji Road, Wuhan, 430014, China.
Chen J; Department of Neurosurgery, Wuhan Brain Hospital, No. 5 Huiji Road, Wuhan, 430014, China.
Shao Q; Department of Neurosurgery, Wuhan Brain Hospital, No. 5 Huiji Road, Wuhan, 430014, China. .
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Źródło :
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery [Childs Nerv Syst] 2021 Aug; Vol. 37 (8), pp. 2701-2705. Date of Electronic Publication: 2020 Sep 26.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/surgery
Glioma*/complications
Glioma*/diagnostic imaging
Glioma*/surgery
Supratentorial Neoplasms*
Child ; Female ; Frontal Lobe ; Humans ; Magnetic Resonance Imaging ; Seizures
Czasopismo naukowe
Tytuł :
A 25-year retrospective, single center analysis of 343 WHO grade II/III glioma patients: implications for grading and temozolomide therapy.
Autorzy :
Steidl E; Senckenberg Institute of Neurooncology, University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany. .; Institute of Neuroradiology, University Hospital, Goethe University Frankfurt am Main, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany. .; German Cancer Consortium (DKTK), Partner site Frankfurt/ Mainz, Frankfurt am Main, Germany. .
Filipski K; Frankfurt Cancer Institute (FCI), University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; Institute of Neurology (Edinger-Institute), University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Partner site Frankfurt/ Mainz, Frankfurt am Main, Germany.
Zeiner PS; Senckenberg Institute of Neurooncology, University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.
Wagner M; Institute of Neuroradiology, University Hospital, Goethe University Frankfurt am Main, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.
Fokas E; Department of Radiooncology, University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.
Forster MT; Department of Neurosurgery, University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.
Ronellenfitsch MW; Senckenberg Institute of Neurooncology, University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Partner site Frankfurt/ Mainz, Frankfurt am Main, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Divé I; Senckenberg Institute of Neurooncology, University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Partner site Frankfurt/ Mainz, Frankfurt am Main, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Steinbach JP; Senckenberg Institute of Neurooncology, University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Partner site Frankfurt/ Mainz, Frankfurt am Main, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Harter PN; Frankfurt Cancer Institute (FCI), University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; Institute of Neurology (Edinger-Institute), University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Partner site Frankfurt/ Mainz, Frankfurt am Main, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Bähr O; Senckenberg Institute of Neurooncology, University Hospital, Goethe University Frankfurt am Main, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Partner site Frankfurt/ Mainz, Frankfurt am Main, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Aug; Vol. 147 (8), pp. 2373-2383. Date of Electronic Publication: 2021 Feb 04.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*drug therapy
Brain Neoplasms/*pathology
Glioma/*drug therapy
Glioma/*pathology
Temozolomide/*therapeutic use
Adult ; Aged ; Aged, 80 and over ; Brain Neoplasms/epidemiology ; Brain Neoplasms/genetics ; Female ; Germany/epidemiology ; Glioma/epidemiology ; Glioma/genetics ; Humans ; Isocitrate Dehydrogenase/genetics ; Male ; Middle Aged ; Mutation ; Neoplasm Grading ; Retrospective Studies ; Survival Analysis ; Treatment Outcome ; World Health Organization ; Young Adult
Czasopismo naukowe
Tytuł :
Design, synthesis and biological evaluation of N-anthraniloyl tryptamine derivatives as pleiotropic molecules for the therapy of malignant glioma.
Autorzy :
Fan X; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China.
Li J; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China.
Long L; School of Pharmaceutical Science, University of South China, Hengyang, 421001, China.
Shi T; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. Electronic address: .
Liu D; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China.
Tan W; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China.
Zhang H; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China.
Wu X; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China.
Lei X; School of Pharmaceutical Science, University of South China, Hengyang, 421001, China. Electronic address: .
Wang Z; School of Pharmaceutical Science, University of South China, Hengyang, 421001, China; School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 15; Vol. 222, pp. 113564. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Antineoplastic Agents/*pharmacology
Glioma/*drug therapy
Tryptamines/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Glioma/metabolism ; Glioma/pathology ; Humans ; Molecular Structure ; Rats ; STAT3 Transcription Factor/antagonists & inhibitors ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Structure-Activity Relationship ; Tryptamines/chemical synthesis ; Tryptamines/chemistry ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
A novel selective mitochondrial-targeted curcumin analog with remarkable cytotoxicity in glioma cells.
Autorzy :
Shi L; Department of Neurosurgery, Affiliated Kunshan Hospital of Jiangsu University, First People's Hospital of Kunshan, Suzhou, 215300, PR China.
Gao LL; Department of Oncology, The People's Hospital of Funing County in Yancheng City, Yancheng, 224400, Jiang Su, PR China.
Cai SZ; Department of Child and Adolescent Healthcare, Children's Hospital of Soochow University, Suzhou, Suzhou, 215021, PR China. Electronic address: .
Xiong QW; Department of Surgery, Children's Hospital of Soochow University, Suzhou, 215021, PR China.
Ma ZR; Department of Surgery, Children's Hospital of Soochow University, Suzhou, 215021, PR China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113528. Date of Electronic Publication: 2021 May 12.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Brain Neoplasms/*drug therapy
Curcumin/*pharmacology
Glioma/*drug therapy
Mitochondria/*drug effects
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Curcumin/chemical synthesis ; Curcumin/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Glioma/metabolism ; Glioma/pathology ; Humans ; Mitochondria/metabolism ; Molecular Structure ; Rats ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
The role of human endogenous retroviruses in gliomas: from etiological perspectives and therapeutic implications.
Autorzy :
Shah AH; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Gilbert M; Neuro-oncology Branch, National Cancer Institute, National Institute of Health, Bethesda, Maryland, USA.
Ivan ME; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Komotar RJ; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Heiss J; Surgical Neurology Branch, NINDS, NIH, Bethesda, Maryland, USA.
Nath A; Translational Neuroscience Center, NINDS, NIH, Bethesda, Maryland, USA.
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Źródło :
Neuro-oncology [Neuro Oncol] 2021 Oct 01; Vol. 23 (10), pp. 1647-1655.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Endogenous Retroviruses*/genetics
Glioma*/drug therapy
Glioma*/genetics
Carcinogenesis ; Epigenesis, Genetic ; Humans
Czasopismo naukowe
Tytuł :
Reproducible imaging-based prediction of molecular subtype and risk stratification of gliomas across different experience levels using a structured reporting system.
Autorzy :
Nam YK; Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul, 05505, Korea.
Park JE; Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul, 05505, Korea. .
Park SY; Department of Statistics and Data Science, Korea National Open University, Seoul, Korea.
Lee M; Department of Radiology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim M; Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul, 05505, Korea.
Nam SJ; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, Korea.
Kim HS; Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul, 05505, Korea.
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Źródło :
European radiology [Eur Radiol] 2021 Oct; Vol. 31 (10), pp. 7374-7385. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
Glioma*/diagnostic imaging
Glioma*/genetics
Humans ; Isocitrate Dehydrogenase/genetics ; Magnetic Resonance Imaging ; Mutation ; Reproducibility of Results ; Risk Assessment
Czasopismo naukowe
Tytuł :
The advanced development of Cx43 and GAP-43 mediated intercellular networking in IDH1 wildtype diffuse and anaplastic gliomas with lower mitotic rate.
Autorzy :
Krigers A; Department of Neurosurgery, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. .
Moser P; Department of Neuropathology, University Hospital of Innsbruck, Innsbruck, Austria.
Fritsch H; Department of Anatomy, Histology and Embryology, Medical University Innsbruck, Innsbruck, Austria.
Demetz M; Department of Neurosurgery, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Brawanski K; Department of Neurosurgery, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Thomé C; Department of Neurosurgery, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Freyschlag CF; Department of Neurosurgery, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Oct; Vol. 147 (10), pp. 3003-3009. Date of Electronic Publication: 2021 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
Biomarkers, Tumor/*metabolism
Brain Neoplasms/*pathology
Connexin 43/*metabolism
GAP-43 Protein/*metabolism
Glioma/*pathology
Isocitrate Dehydrogenase/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Brain Neoplasms/surgery ; Female ; Follow-Up Studies ; Glioma/genetics ; Glioma/metabolism ; Glioma/surgery ; Humans ; Male ; Middle Aged ; Mitosis ; Prognosis ; Young Adult
Czasopismo naukowe
Tytuł :
A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.
Autorzy :
Fangusaro J; Department of Hematology, Oncology, and Stem Cell Transplantation, Children's Healthcare of Atlanta and Emory University, Atlanta, Georgia, USA.
Onar-Thomas A; Department of Biostatistics St. Jude Children's Research Center, Memphis, Tennessee, USA.
Poussaint TY; St. Jude Children's Research Center, Memphis, Tennessee, USA.; Department of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Wu S; Department of Biostatistics St. Jude Children's Research Center, Memphis, Tennessee, USA.
Ligon AH; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Lindeman N; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Campagne O; Department of Pharmaceutical Sciences St. Jude Children's Research Center, Memphis, Tennessee, USA.
Banerjee A; Center for Cancer and Blood Disorders, University of California, San Francisco, California, USA.
Gururangan S; Department of Neurosurgery, University of Florida, Gainesville, Florida, USA.
Kilburn LB; Division of Oncology Children's National Hospital , Washington DC, USA.
Goldman S; Children's National Hospital, Washington DC, USA.; Department of Hematology, Oncology, Neuro-Oncology and Stem Cell Transplantation.
Qaddoumi I; Department of Oncology St. Jude Children's Research Center, Memphis, Tennessee, USA.
Baxter P; Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.; Department of Hematology and Oncology, Texas Children's Hospital, Houston, Texas, USA.
Vezina G; Department of Radiology Children's National Hospital , Washington DC, USA.
Bregman C; Department of Medical Imaging.
Patay Z; Department of Diagnostic Imaging St. Jude Children's Research Center, Memphis, Tennessee, USA.
Jones JY; Department of Radiology Nationwide Children's Hospital, Columbus, Ohio, USA.
Stewart CF; Department of Pharmaceutical Sciences St. Jude Children's Research Center, Memphis, Tennessee, USA.
Fisher MJ; Nationwide Children's Hospital, Columbus, Ohio, USA.; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Doyle LA; Investigational Drug Branch, National Cancer Institute and Cancer Therapy Evaluation Program, Rockville, Maryland, USA.
Smith M; Clinical Investigation Branch, National Cancer Institute and Cancer Therapy Evaluation Program, Rockville, Maryland, USA.
Dunkel IJ; National Cancer Institute and Cancer Therapy Evaluation Program, Rockville, Maryland, USA.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Fouladi M; Department of Hematology and Oncology Nationwide Children's Hospital, Columbus, Ohio, USA.
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Źródło :
Neuro-oncology [Neuro Oncol] 2021 Oct 01; Vol. 23 (10), pp. 1777-1788.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms*/drug therapy
Neurofibromatosis 1*
Optic Nerve Glioma*/drug therapy
Benzimidazoles ; Child ; Humans
Czasopismo naukowe
Tytuł :
Strategy of De Novo Design toward First-In-Class Imaging Agents for Simultaneously Differentiating Glioma Boundary and Grades.
Autorzy :
Yan F; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Zhuang J; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Yu Q; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Dou Z; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Jiang X; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Tan S; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Han Y; Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Wu X; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Zang Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Li C; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Li J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Chen H; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Hu L; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Li X; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Chen G; College of Pharmaceutical Sciences, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
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Źródło :
ACS sensors [ACS Sens] 2021 Sep 24; Vol. 6 (9), pp. 3330-3339. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computational Biology*
Glioma*/diagnosis
Animals ; Humans ; Mice
Czasopismo naukowe
Tytuł :
Serum lncRNA-ANRIL and SOX9 expression levels in glioma patients and their relationship with poor prognosis.
Autorzy :
Sun Y; Department of Neurosurgery, Guangrao County People's Hospital, No. 180 Huayuan Road, Dongying, Guangrao County, 257300, P.R. China.
Jing Y; Department of Neurosurgery, The Second People's Hospital Of Dongying, Dongying, 257335, P.R. China.
Zhang Y; Department of Neurosurgery, Guangrao County People's Hospital, No. 180 Huayuan Road, Dongying, Guangrao County, 257300, P.R. China. .
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Źródło :
World journal of surgical oncology [World J Surg Oncol] 2021 Sep 23; Vol. 19 (1), pp. 287. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji :
Journal Article
MeSH Terms :
Glioma*/diagnosis
Glioma*/genetics
RNA, Long Noncoding*/genetics
SOX9 Transcription Factor*/genetics
Apoptosis ; Cell Proliferation ; Humans ; Prognosis
Czasopismo naukowe
Tytuł :
A serum-based DNA methylation assay provides accurate detection of glioma.
Autorzy :
Sabedot TS; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.; Omics Laboratory, Henry Ford Health System, Detroit, Michigan, USA.
Malta TM; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.; Omics Laboratory, Henry Ford Health System, Detroit, Michigan, USA.
Snyder J; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.; Omics Laboratory, Henry Ford Health System, Detroit, Michigan, USA.; Department of Neuro Oncology, Henry Ford Health System, Detroit, Michigan, USA.
Nelson K; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.
Wells M; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.; Omics Laboratory, Henry Ford Health System, Detroit, Michigan, USA.
deCarvalho AC; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.
Mukherjee A; Department of Pathology, Henry Ford Health System, Detroit, Michigan, USA.
Chitale DA; Department of Pathology, Henry Ford Health System, Detroit, Michigan, USA.
Mosella MS; Omics Laboratory, Henry Ford Health System, Detroit, Michigan, USA.
Sokolov A; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
Asmaro KP; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.; Omics Laboratory, Henry Ford Health System, Detroit, Michigan, USA.
Robin A; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.
Rosenblum ML; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.
Mikkelsen T; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.
Rock J; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.
Poisson LM; Department of Public Health Sciences, Henry Ford Health System, Detroit, Michigan, USA.
Lee I; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.
Walbert T; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.; Department of Neuro Oncology, Henry Ford Health System, Detroit, Michigan, USA.
Kalkanis S; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.
Iavarone A; Institute for Cancer Genetics, Department of Pathology and Cell Biology, Department of Neurology, Columbia University Medical Center, New York, New York, USA.
Castro AV; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.; Omics Laboratory, Henry Ford Health System, Detroit, Michigan, USA.
Noushmehr H; Department of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, Michigan, USA.; Omics Laboratory, Henry Ford Health System, Detroit, Michigan, USA.
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Źródło :
Neuro-oncology [Neuro Oncol] 2021 Sep 01; Vol. 23 (9), pp. 1494-1508.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Brain Neoplasms*/diagnosis
Brain Neoplasms*/genetics
Glioma*/diagnosis
Glioma*/genetics
Biomarkers, Tumor/genetics ; DNA Methylation ; Epigenomics ; Humans ; Liquid Biopsy
Czasopismo naukowe
Tytuł :
Prognostic significance of genome-wide DNA methylation profiles within the randomized, phase 3, EORTC CATNON trial on non-1p/19q deleted anaplastic glioma.
Autorzy :
Tesileanu CMS; Neurology Department, Erasmus MC, Rotterdam, the Netherlands.
van den Bent MJ; Neurology Department, Erasmus MC, Rotterdam, the Netherlands.
Sanson M; Sorbonne Université, Hôpitaux Universitaires La Pitié Salpêtrière, Paris, France.
Wick W; Neurology Department, Universitätsklinikum Heidelberg, Heidelberg, Germany.
Brandes AA; Medical Oncology Department, AUSL-IRCCS Scienze Neurologiche, Bologna, Italy.
Clement PM; Oncology Department, KU Leuven and Medical Oncology Department, UZ Leuven, Leuven, Belgium.
Erridge SC; Neuro-Oncology Centre Edinburgh, Western General Hospital, Edinburgh, UK.
Vogelbaum MA; Neuro-Oncology Department, Moffitt Cancer Center, Tampa, Florida, USA.
Nowak AK; University of Western Australia, Perth, Australia.; Co-Operative Group for Neuro-Oncology, University of Sydney, Sydney, Australia.; Medical Oncology Department, Sir Charles Gairdner Hospital, Nedlands, Australia.
Baurain JF; Medical Oncology Department, King Albert II Cancer Institute, Cliniques universitaires Saint-Luc, Brussels, Belgium.
Mason WP; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
Wheeler H; Northern Sydney Cancer Centre, Sydney, Australia.
Chinot OL; Neuro-Oncology Department, Aix-Marseille University, Marseille, France.
Gill S; Medical Oncology Department, Alfred Hospital, Melbourne, Australia.
Griffin M; Clinical Oncology Department, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Rogers L; Radiation Oncology Department, Gammawest Cancer Services, Salt Lake City, Utah, USA.
Taal W; Neurology Department, Erasmus MC, Rotterdam, the Netherlands.
Rudà R; Neuro-Oncology Department, University of Turin, Turin, Italy.
Weller M; Neurology Department, University Hospital of Zurich, Zurich, Switzerland.
McBain C; Clinical Oncology Department, The Christie NHS Foundation Trust, Manchester, UK.
van Linde ME; Medical Oncology Department, Amsterdam UMC, Amsterdam, the Netherlands.
Sabedot TS; Neurosurgery Department, Henry Ford Health System, Detroit, Michigan, USA.
Hoogstrate Y; Neurology Department, Erasmus MC, Rotterdam, the Netherlands.
von Deimling A; Neuropathology Department, Ruprecht-Karls-University, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
de Heer I; Neurology Department, Erasmus MC, Rotterdam, the Netherlands.
van IJcken WFJ; Biomics Center, Erasmus MC, Rotterdam, the Netherlands.
Brouwer RWW; Biomics Center, Erasmus MC, Rotterdam, the Netherlands.
Aldape K; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
Jenkins RB; Pathology Department, Mayo Clinic, Rochester, Minnesota, USA.
Dubbink HJ; Pathology Department, Erasmus MC, Rotterdam, the Netherlands.
Kros JM; Pathology Department, Erasmus MC, Rotterdam, the Netherlands.
Wesseling P; Pathology Department, Amsterdam UMC, Amsterdam, the Netherlands.; Princess Máxima Center, Utrecht, the Netherlands.
Cheung KJ; EORTC HQ, Brussels, Belgium.
Golfinopoulos V; EORTC HQ, Brussels, Belgium.
Baumert BG; Radiation Oncology Department, Maastricht UMC, Maastricht, the Netherlands.; Radiation Oncology Institute, Cantonal Hospital Graubünden, Chur, Switzerland.
Gorlia T; EORTC HQ, Brussels, Belgium.
Noushmehr H; Neurosurgery Department, Henry Ford Health System, Detroit, Michigan, USA.
French PJ; Neurology Department, Erasmus MC, Rotterdam, the Netherlands.
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Źródło :
Neuro-oncology [Neuro Oncol] 2021 Sep 01; Vol. 23 (9), pp. 1547-1559.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Glioma*/genetics
Glioma*/therapy
Adult ; Chromosomes, Human, Pair 1 ; DNA Copy Number Variations ; DNA Methylation ; Homozygote ; Humans ; Isocitrate Dehydrogenase/genetics ; Mutation ; Prognosis ; Prospective Studies ; Sequence Deletion
Czasopismo naukowe
Tytuł :
Novel roles of VAT1 expression in the immunosuppressive action of diffuse gliomas.
Autorzy :
Yang P; Department of Neurosurgery, Fengtai District, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring Road West, Beijing, 100070, China.; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Wang K; Department of Gamma Knife, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Zhang C; Department of Neurosurgery, Fengtai District, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring Road West, Beijing, 100070, China.; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Wang Z; Department of Neurosurgery, Fengtai District, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring Road West, Beijing, 100070, China.; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Liu Q; Department of Neurosurgery, Fengtai District, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring Road West, Beijing, 100070, China.
Wang J; Department of Neurosurgery, Fengtai District, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring Road West, Beijing, 100070, China.
Jiang T; Department of Neurosurgery, Fengtai District, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring Road West, Beijing, 100070, China. .; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China. .; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China. .; China National Clinical Research Center for Neurological Diseases, Beijing, China. .; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China. .
Shan X; Department of Radiotherapy, Fengtai District, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring Road West, Beijing, 100070, China. .; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China. .; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Sep; Vol. 70 (9), pp. 2589-2600. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Immunomodulation*
Glioma/*genetics
Glioma/*immunology
Vesicular Transport Proteins/*genetics
Biomarkers, Tumor ; Brain Neoplasms/genetics ; Brain Neoplasms/immunology ; Brain Neoplasms/pathology ; Computational Biology/methods ; Gene Expression Profiling ; Gene Ontology ; Glioma/pathology ; Humans ; Immune Checkpoint Proteins/genetics ; Immune Checkpoint Proteins/metabolism ; Mutation ; Neoplasm Grading ; Prognosis ; ROC Curve
Czasopismo naukowe
Tytuł :
Bevacizumab in recurrent high-grade glioma: a single institution retrospective analysis on 92 patients.
Autorzy :
Detti B; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
Scoccianti S; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
Teriaca MA; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy. .
Maragna V; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
Lorenzetti V; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
Lucidi S; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
Bellini C; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
Greto D; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
Desideri I; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
Livi L; Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla 1, 50134, Florence, Italy.
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Źródło :
La Radiologia medica [Radiol Med] 2021 Sep; Vol. 126 (9), pp. 1249-1254. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Immunological/*therapeutic use
Bevacizumab/*therapeutic use
Brain Neoplasms/*drug therapy
Glioma/*drug therapy
Neoplasm Recurrence, Local/*drug therapy
Adult ; Aged ; Antineoplastic Agents, Immunological/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Bevacizumab/adverse effects ; Brain Neoplasms/mortality ; Brain Neoplasms/pathology ; Brain Neoplasms/surgery ; Female ; Glioblastoma/drug therapy ; Glioblastoma/mortality ; Glioblastoma/pathology ; Glioma/mortality ; Glioma/pathology ; Glioma/surgery ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Retrospective Studies ; Survival Analysis
Czasopismo naukowe

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