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Tytuł:
Voxel-based 18F-FET PET segmentation and automatic clustering of tumor voxels: A significant association with IDH1 mutation status and survival in patients with gliomas
Autorzy:
Blanc-Durand, Paul
Van Der Gucht, Axel
Verger, Antoine
Langen, Karl-Josef
Dunet, Vincent
Bloch, Jocelyne
Brouland, Jean-Philippe
Nicod-Lalonde, Marie
Schaefer, Niklaus
Prior, John O.
Pokaż więcej
Temat:
ddc:500
CZT
SPECT
bone scintigraphy
vertebral fracture
standardized uptake value
[INFO.INFO-IM]Computer Science [cs]/Medical Imaging
[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Adult
Biomarkers, Tumor
Cluster Analysis
Female
Follow-Up Studies
Glioma/diagnostic imaging
Glioma/genetics
Glioma/mortality
Glioma/pathology
Humans
Image Processing, Computer-Assisted
Isocitrate Dehydrogenase/genetics
Kaplan-Meier Estimate
Male
Middle Aged
Mutation
Neoplasm Grading
Neoplasm Staging
Positron Emission Tomography Computed Tomography
Positron-Emission Tomography
Prognosis
Tyrosine/analogs & derivatives
lcsh:Medicine
lcsh:R
lcsh:Science
lcsh:Q
Multidisciplinary
Medicine
business.industry
business
Voxel
computer.software_genre
computer
IDH1 Mutation
Cluster analysis
Tumor progression
Nuclear medicine
Correlation and dependence
Brain tumor
medicine.disease
Positron emission tomography
medicine.diagnostic_test
IDH1
Research Article
Medicine and Health Sciences
Oncology
Cancers and Neoplasms
Neurological Tumors
Glioma
Neurology
Research and Analysis Methods
Imaging Techniques
Neuroimaging
Positron Emission Tomography
Biology and Life Sciences
Neuroscience
Diagnostic Medicine
Diagnostic Radiology
Tomography
Radiology and Imaging
Astrocytoma
Astrocytoma Cells
Biological Cultures
Cell Cultures
Cultured Tumor Cells
Magnetic Resonance Imaging
Oligodendroglioma
Cancer Detection and Diagnosis
Blastomas
Glioblastoma Multiforme
Źródło:
PLoS one 13(6), e0199379-(2018). doi:10.1371/journal.pone.0199379
PLoS ONE
PLoS ONE, Public Library of Science, 2018, 13 (6), pp.e0199379. ⟨10.1371/journal.pone.0199379⟩
PloS one, vol. 13, no. 6, pp. e0199379
PLoS ONE, Vol 13, Iss 6, p e0199379 (2018)
Europe PubMed Central
PLoS one 13(6), e0199379 (2018). doi:10.1371/journal.pone.0199379
PLoS ONE, Public Library of Science, 2018, 13, ⟨10.1371/journal.pone.0199379⟩
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d035e91b7de04e45a58e0d493c980c
https://juser.fz-juelich.de/search?p=id:"FZJ-2018-04295"
Szczegóły
Tytuł:
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Autorzy:
Venteicher, Andrew S.
Tirosh, Itay
Hebert, Christine
Yizhak, Keren
Neftel, Cyril
Filbin, Mariella G.
Hovestadt, Volker
Escalante, Leah E.
Shaw, McKenzie L.
Rodman, Christopher
Gillespie, Shawn M.
Dionne, Danielle
Luo, Christina C.
Ravichandran, Hiranmayi
Mylvaganam, Ravindra
Mount, Christopher
Onozato, Maristela L.
Nahed, Brian V.
Wakimoto, Hiroaki
Curry, William T.
Iafrate, A. John
Rivera, Miguel N.
Frosch, Matthew P.
Golub, Todd R.
Brastianos, Priscilla K.
Getz, Gad
Patel, Anoop P.
Monje, Michelle
Cahill, Daniel P.
Rozenblatt-Rosen, Orit
Louis, David N.
Bernstein, Bradley E.
Regev, Aviv
Suvà, Mario L.
Pokaż więcej
Temat:
Article
Brain Neoplasms/classification
Brain Neoplasms/genetics
Brain Neoplasms/pathology
Cell Lineage
Glioma/classification
Glioma/genetics
Glioma/pathology
Humans
Isocitrate Dehydrogenase/genetics
Macrophages
Microglia/metabolism
Microglia/pathology
Neoplasm Grading
Neoplastic Stem Cells/metabolism
Neoplastic Stem Cells/pathology
Principal Component Analysis
Sequence Analysis, RNA
Single-Cell Analysis
Tumor Microenvironment
Multidisciplinary
Isocitrate dehydrogenase
Genetics
Cell
medicine.anatomical_structure
medicine
Astrocytoma
medicine.disease
Tumor microenvironment
Single-cell analysis
Oligodendroglioma
Biology
Glioma
RNA
Źródło:
Science, vol. 355, no. 6332, pp. 1391
PMC
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7d666055f7b5926de64370899646af
https://europepmc.org/articles/PMC5519096/
Szczegóły
Tytuł:
Zoledronic acid induces apoptosis via stimulating the expressions of ERN1, TLR2, and IRF5 genes in glioma cells
Autorzy:
Zeynep Mutlu
Levent Elmas
Cumhur Gündüz
Ozgun Ozalp
Yavuz Dodurga
Cansu Caliskan Kurt
Cigir Biray Avci
Bakiye Goker
Burcu Erbaykent Tepedelen
Pokaż więcej
Temat:
Gene expression
Glioma
Zoledronic acid
carrier protein
cytokine
DNA
endoplasmic reticulum to nucleus signaling 1
immunoglobulin enhancer binding protein
interferon
interferon regulatory factor 5
toll like receptor
toll like receptor 2
unclassified drug
antineoplastic agent
bisphosphonic acid derivative
bone density conservation agent
ERN1 protein, human
imidazole derivative
interferon regulatory factor
IRF5 protein, human
protein serine threonine kinase
ribonuclease
antineoplastic activity
apoptosis
Article
astrocytoma cell
concentration response
controlled study
DNA fragmentation
drug cytotoxicity
epithelioid cell
ERN1 gene
glioblastoma
glioma cell
human
human cell
in vitro study
IRF5 gene
priority journal
quantitative analysis
reverse transcription polymerase chain reaction
signal transduction
TLR2 gene
tumor suppressor gene
cell survival
drug effects
gene expression profiling
gene expression regulation
genetics
tumor cell line
Antineoplastic Agents
Bone Density Conservation Agents
Cell Line, Tumor
Diphosphonates
Endoribonucleases
Gene Expression Regulation, Neoplastic
Humans
Imidazoles
Interferon Regulatory Factors
Protein-Serine-Threonine Kinases
Toll-Like Receptor 2
Antineoplastic Agents/pharmacology
Apoptosis/*drug effects
Bone Density Conservation Agents/*pharmacology
Cell Survival/drug effects/genetics
DNA Fragmentation
Diphosphonates/*pharmacology
Endoribonucleases/*genetics
Gene Expression Profiling
Gene Expression Regulation, Neoplastic/*drug effects
Glioma/*genetics
Imidazoles/*pharmacology
Interferon Regulatory Factors/*genetics
Protein-Serine-Threonine Kinases/*genetics
Toll-Like Receptor 2/genetics
Zoledroni
General Medicine
Cancer research
medicine.disease
medicine
TLR2
Signal transduction
Cytotoxic T cell
Cell culture
Temozolomide
medicine.drug
Immunology
Apoptosis
business.industry
business
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c32341db0ef898b6af788e1e2085649
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/9608
Szczegóły
Tytuł:
Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment
Autorzy:
Katsushima, K.
Natsume, A.
Ohka, F.
Shinjo, K.
Hatanaka, A.
Ichimura, N.
Sato, S.
Takahashi, S.
Kimura, Hiroshi
Totoki, Y.
Shibata, T.
Naito, M.
Kim, H. J.
Miyata, K.
Kataoka, K.
Kondo, Y.
Pokaż więcej
Temat:
Animals
Brain Neoplasms/*genetics/*therapy
Carcinogenesis/genetics/pathology
Cell Differentiation/genetics
Enhancer of Zeste Homolog 2 Protein/metabolism
Exons/genetics
Female
Gene Expression Regulation, Neoplastic
Glioma/*genetics/*therapy
Humans
Mice, Inbred NOD
Mice, SCID
MicroRNAs/genetics/metabolism
Neoplastic Stem Cells/metabolism/pathology
Neurons/metabolism
Polycomb Repressive Complex 2/metabolism
Protein Binding
Proto-Oncogene Proteins c-myc/metabolism
RNA, Long Noncoding/genetics/*metabolism
RNA, Messenger/genetics/metabolism
Receptor, Notch1/*metabolism
SOXB1 Transcription Factors/metabolism
Xenograft Model Antitumor Assays
YY1 Transcription Factor/metabolism
Science
Article
General Physics and Astronomy
General Biochemistry, Genetics and Molecular Biology
General Chemistry
Biology
Cancer research
Methylation
Stem cell
Population
education.field_of_study
education
Histone
biology.protein
Non-coding RNA
Regulation of gene expression
Glioma
medicine.disease
medicine
Notch signaling pathway
fungi
Źródło:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4ba4865d3c825af20cfcc6dd8cb7d1
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100821247
Szczegóły
Tytuł:
Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging
Autorzy:
Kazuhiko Kurozumi
Sharif Moeniralm
Davide Gianni
Jan E. Carette
Yi Tang
E. Antonio Chiocca
Ralph Weissleder
Balveen Kaur
W. Peter Vandertop
Clemens M.F. Dirven
Martine L.M. Lamfers
Giulia Fulci
Yoshinaga Saeki
Victor W. van Beusechem
Pokaż więcej
Temat:
Drug Discovery
Pharmacology
Genetics
Molecular Biology
Molecular Medicine
Bioluminescence imaging
Luciferase
Oncolytic virus
Transgene
Oncolytic adenovirus
Adenoviridae
medicine.disease_cause
medicine
Gene expression
Biology
Molecular biology
Transplantation
Adenoviridae/genetics
Animals
Antigens, CD/analysis
Antigens, Differentiation, Myelomonocytic/analysis
Antineoplastic Agents, Alkylating/administration & dosage
Cell Line
Cell Line, Tumor
Cyclophosphamide/administration & dosage
Female
Genetic Vectors/administration & dosage
Glioma/genetics
Humans
Immunohistochemistry
Leukocyte Common Antigens/analysis
Luciferases/genetics
Luminescent Measurements/methods
Mice
Mice, Inbred NOD
Mice, Nude
Mice, SCID
Mice, Transgenic
Neoplasms, Experimental/genetics
Oncolytic Viruses/genetics
Transgenes/genetics
Transplantation, Heterologous
Article
Antigens
CD/analysis
Differentiation
Myelomonocytic/analysis
Antineoplastic Agents
Alkylating/administration & dosage
Tumor
Inbred NOD
Nude
SCID
Transgenic
Neoplasms
Experimental/genetics
Heterologous
Źródło:
Molecular Therapy, 14(6), 779-88. Nature Publishing Group
Molecular therapy, 14(6), 779-788. Nature Publishing Group
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd759a98e65cf3625a6a67763396c585
https://api.elsevier.com/content/article/PII:S1525001606016376?httpAccept=text/plain
Szczegóły
Tytuł:
Autocrine control of glioma cells adhesion and migration through IRE1 -mediated cleavage of SPARC mRNA
Autorzy:
Dejeans, N.
Pluquet, O.
Lhomond, S.
Grise, F.
Bouchecareilh, M.
Juin, A.
Meynard-Cadars, M.
Bidaud-Meynard, A.
Gentil, C.
Moreau, V.
Saltel, F.
Chevet, E.
Pokaż więcej
Temat:
Cell Biology
Cell migration
Cell biology
Endoribonuclease activity
Biology
Endoplasmic reticulum
Tumor microenvironment
Autocrine signalling
RHOA
biology.protein
Unfolded protein response
Tumor progression
IRE1
Cell adhesion
cell migration
SPARC
MESH: Actin Cytoskeleton/metabolism
MESH: Autocrine Communication*/genetics
MESH: Extracellular Matrix Proteins/metabolism
MESH: Gene Expression Profiling
MESH: Gene Expression Regulation, Neoplastic
MESH: Glioma/genetics
MESH: Glioma/pathology
MESH: Humans
MESH: Models, Biological
MESH: Osteonectin/genetics
MESH: Osteonectin/metabolism
MESH: Protein-Serine-Threonine Kinases/metabolism
MESH: Brain Neoplasms/genetics
MESH: RNA, Messenger/genetics
MESH: RNA, Messenger/metabolism
MESH: Signal Transduction/genetics
MESH: Spheroids, Cellular/pathology
MESH: Tumor Cells, Cultured
MESH: rhoA GTP-Binding Protein/metabolism
MESH: Brain Neoplasms/pathology
MESH: Cell Adhesion/genetics
MESH: Cell Movement*/genetics
MESH: Cell Proliferation
MESH: Down-Regulation/genetics
MESH: Endoribonucleases/metabolism
MESH: Extracellular Matrix Proteins/genetics
[SDV]Life Sciences [q-bio]
[SDV.CAN]Life Sciences [q-bio]/Cancer
Źródło:
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2012, 125 (18), pp.4278-4287. ⟨10.1242/jcs.099291⟩
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbd10b4bc4abb9b4a70974af67d4893
Szczegóły
Wyświetlanie 1-20 z 30

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