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Tytuł :
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro.
Autorzy :
Tian X; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Xu Z; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Hu P; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Yu Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Li Z; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Ma Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Chen M; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Sun Z; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Liu F; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Li J; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: .
Huang C; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2020 Dec 05; Vol. 263, pp. 113215. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
MeSH Terms :
Phellodendron*
Gluconeogenesis/*physiology
Hepatocytes/*metabolism
Hypoglycemic Agents/*chemistry
Liver/*metabolism
Animals ; Cells, Cultured ; Gluconeogenesis/drug effects ; Hepatocytes/drug effects ; Hypoglycemic Agents/isolation & purification ; Hypoglycemic Agents/pharmacology ; Liver/drug effects ; Male ; Plant Bark ; Quinolizines/chemistry ; Quinolizines/isolation & purification ; Quinolizines/pharmacology ; Rats ; Rats, Wistar ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Tytuł :
Heat stress alters muscle protein and amino acid metabolism and accelerates liver gluconeogenesis for energy supply in broilers.
Autorzy :
Ma B; College of Animal Science and Technology, Key Laboratory of Animal Origin Food Production and Safety Guarantee of Jiangsu Province, Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control, Joint International Research Laboratory of Animal Health and Food Safety, National Experimental Teaching Demonstration Center of Animal Science, Nanjing Agricultural University, Nanjing 210095, PR China.
Zhang L; College of Animal Science and Technology, Key Laboratory of Animal Origin Food Production and Safety Guarantee of Jiangsu Province, Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control, Joint International Research Laboratory of Animal Health and Food Safety, National Experimental Teaching Demonstration Center of Animal Science, Nanjing Agricultural University, Nanjing 210095, PR China.
Li J; College of Animal Science and Technology, Key Laboratory of Animal Origin Food Production and Safety Guarantee of Jiangsu Province, Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control, Joint International Research Laboratory of Animal Health and Food Safety, National Experimental Teaching Demonstration Center of Animal Science, Nanjing Agricultural University, Nanjing 210095, PR China.
Xing T; College of Animal Science and Technology, Key Laboratory of Animal Origin Food Production and Safety Guarantee of Jiangsu Province, Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control, Joint International Research Laboratory of Animal Health and Food Safety, National Experimental Teaching Demonstration Center of Animal Science, Nanjing Agricultural University, Nanjing 210095, PR China.
Jiang Y; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, PR China.
Gao F; College of Animal Science and Technology, Key Laboratory of Animal Origin Food Production and Safety Guarantee of Jiangsu Province, Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control, Joint International Research Laboratory of Animal Health and Food Safety, National Experimental Teaching Demonstration Center of Animal Science, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address: .
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Źródło :
Poultry science [Poult Sci] 2021 Jan; Vol. 100 (1), pp. 215-223. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acids*/metabolism
Chickens*/metabolism
Energy Metabolism*
Gluconeogenesis*/physiology
Liver*/metabolism
Muscle Proteins*/metabolism
Animals ; Heat-Shock Response ; Hot Temperature
Czasopismo naukowe
Tytuł :
Prominin-1-Radixin axis controls hepatic gluconeogenesis by regulating PKA activity.
Autorzy :
Lee H; Tunneling Nanotube Research Center, Korea University, Seoul, Korea.; Division of Life Sciences, Korea University, Seoul, Korea.
Yu DM; Tunneling Nanotube Research Center, Korea University, Seoul, Korea.; Division of Life Sciences, Korea University, Seoul, Korea.
Park JS; Tunneling Nanotube Research Center, Korea University, Seoul, Korea.; Division of Life Sciences, Korea University, Seoul, Korea.
Lee H; Tunneling Nanotube Research Center, Korea University, Seoul, Korea.; Division of Life Sciences, Korea University, Seoul, Korea.
Kim JS; Tunneling Nanotube Research Center, Korea University, Seoul, Korea.; Division of Life Sciences, Korea University, Seoul, Korea.
Kim HL; Laboratory of Electron Microscope, Integrative Research Support Center, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Koo SH; Tunneling Nanotube Research Center, Korea University, Seoul, Korea.; Division of Life Sciences, Korea University, Seoul, Korea.
Lee JS; Department of Molecular Medicine, Inha University College of Medicine, Incheon, Korea.; Hypoxia-related Disease Research Center, Inha University College of Medicine, Incheon, Korea.
Lee S; Tunneling Nanotube Research Center, Korea University, Seoul, Korea.; Division of Life Sciences, Korea University, Seoul, Korea.
Ko YG; Tunneling Nanotube Research Center, Korea University, Seoul, Korea.; Division of Life Sciences, Korea University, Seoul, Korea.
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Źródło :
EMBO reports [EMBO Rep] 2020 Nov 05; Vol. 21 (11), pp. e49416. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gluconeogenesis*/genetics
Glucose*/metabolism
AC133 Antigen/genetics ; AC133 Antigen/metabolism ; Animals ; Cytoskeletal Proteins ; Hepatocytes ; Liver/metabolism ; Membrane Proteins ; Mice
Czasopismo naukowe
Tytuł :
Tracking the carbons supplying gluconeogenesis.
Autorzy :
Shah AM; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey, USA.
Wondisford FE; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey, USA .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Oct 16; Vol. 295 (42), pp. 14419-14429. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Gluconeogenesis*
Carbon/*metabolism
Diabetes Mellitus, Type 2/*pathology
Animals ; Carbon Isotopes/metabolism ; Diabetes Mellitus, Type 2/metabolism ; Glucose/metabolism ; Glycogen/metabolism ; Humans ; Hyperglycemia/metabolism ; Hyperglycemia/pathology ; Metabolomics
Czasopismo naukowe
Tytuł :
[Effects of microRNA-106b on hepatic gluconeogenesis and its underlying mechanism].
Autorzy :
Fu XD; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Wang SY; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Zhu ZQ; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Deng YP; Department of Pediatrics, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
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Źródło :
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology [Zhongguo Ying Yong Sheng Li Xue Za Zhi] 2020 Sep; Vol. 36 (5), pp. 503-508.
Typ publikacji :
Journal Article
MeSH Terms :
Gluconeogenesis*
MicroRNAs*/genetics
MicroRNAs*/metabolism
Animals ; Glucose-6-Phosphatase/genetics ; Glucose-6-Phosphatase/metabolism ; Humans ; Liver/metabolism ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
A critical role for hepatic protein arginine methyltransferase 1 isoform 2 in glycemic control.
Autorzy :
Ma Y; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.; Department of cardiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Liu S; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Jun H; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Wang J; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Fan X; International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, Huazhong University of Science and Technology, Wuhan, China.; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Li G; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Yin L; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA.
Rui L; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA.
Weinman SA; Department of Internal Medicine and the Liver Center, University of Kansas Medical Center, Kansas City, KS, USA.
Gong J; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.; International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, Huazhong University of Science and Technology, Wuhan, China.; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Wu J; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Nov; Vol. 34 (11), pp. 14863-14877. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gluconeogenesis*
Hepatocytes/*metabolism
Hyperglycemia/*genetics
Protein-Arginine N-Methyltransferases/*metabolism
Animals ; Cells, Cultured ; Gain of Function Mutation ; Glucagon/metabolism ; Glucose/metabolism ; Hep G2 Cells ; Humans ; Hyperglycemia/metabolism ; Mice ; Mice, Inbred C57BL ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Protein-Arginine N-Methyltransferases/genetics
Czasopismo naukowe
Tytuł :
Multiple omics analysis reveals that high fiber diets promote gluconeogenesis and inhibit glycolysis in muscle.
Autorzy :
Wu J; College of Animal Science and Technology, Inner Mongolia University for Nationalities, Tongliao, 028000, China. .; Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, 010031, China. .
Yang D; Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, 010031, China.
Gong H; College of Life Science, Inner Mongolia University for Nationalities, Tongliao, 028000, China.
Qi Y; Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, 010031, China.
Sun H; Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, 010031, China.
Liu Y; Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, 010031, China.
Liu Y; Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, 010031, China.
Qiu X; Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, 010031, China.
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Źródło :
BMC genomics [BMC Genomics] 2020 Sep 24; Vol. 21 (1), pp. 660. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article
MeSH Terms :
Gluconeogenesis*
Glycolysis*
Transcriptome*
Dietary Fiber/*metabolism
Muscle, Skeletal/*metabolism
Sheep/*metabolism
Animal Nutritional Physiological Phenomena ; Animals ; Arachidonic Acid/metabolism ; Gastrointestinal Microbiome ; Linoleic Acid/metabolism ; Metabolome ; Red Meat/standards ; Sheep/genetics ; Sheep/physiology
Czasopismo naukowe
Tytuł :
Astragaloside IV relieves gestational diabetes mellitus in genetic mice through reducing hepatic gluconeogenesis.
Autorzy :
Zhang R; Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou 061000, Hebei, China.
Xing B; Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou 061000, Hebei, China.
Zhao J; Cangzhou Hospital of Integrated TCM-WM·HEBEI, No. 31 Huanghe Road, Cangzhou 061000, Hebei, China.
Zhang X; Cangzhou Hospital of Integrated TCM-WM·HEBEI, No. 31 Huanghe Road, Cangzhou 061000, Hebei, China.
Zhou L; Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou 061000, Hebei, China.
Yang S; Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou 061000, Hebei, China.
Wang Y; Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou 061000, Hebei, China.
Yang F; Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou 061000, Hebei, China.
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Źródło :
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Jul; Vol. 98 (7), pp. 466-472. Date of Electronic Publication: 2020 Mar 11.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes, Gestational/*drug therapy
Drugs, Chinese Herbal/*pharmacology
Gluconeogenesis/*drug effects
Hypoglycemic Agents/*pharmacology
Saponins/*pharmacology
Triterpenes/*pharmacology
Administration, Oral ; Animals ; Blood Glucose/analysis ; Blood Glucose/metabolism ; Cyclic AMP/analysis ; Cyclic AMP/metabolism ; Diabetes, Gestational/blood ; Diabetes, Gestational/diagnosis ; Diabetes, Gestational/genetics ; Disease Models, Animal ; Drugs, Chinese Herbal/therapeutic use ; Female ; Gene Expression Regulation/drug effects ; Gluconeogenesis/genetics ; Glucose Tolerance Test ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/blood ; Insulin/metabolism ; Leptin/genetics ; Lipids/blood ; Liver/drug effects ; Liver/metabolism ; Metformin/pharmacology ; Metformin/therapeutic use ; Mice ; Mice, Transgenic ; Pregnancy ; Saponins/therapeutic use ; Triterpenes/therapeutic use
Czasopismo naukowe
Tytuł :
Propionate enhances the expression of key genes involved in the gluconeogenic pathway in bovine intestinal epithelial cells.
Autorzy :
Zhan K; Institute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Yang TY; Institute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Chen Y; Institute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Jiang MC; Institute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Zhao GQ; Institute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China. Electronic address: .
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Źródło :
Journal of dairy science [J Dairy Sci] 2020 Jun; Vol. 103 (6), pp. 5514-5524. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Journal Article
MeSH Terms :
Cattle/*physiology
Fatty Acids, Volatile/*metabolism
Gene Expression Regulation, Enzymologic/*drug effects
Gluconeogenesis/*drug effects
Propionates/*pharmacology
Animals ; Cattle/genetics ; Cells, Cultured ; Epithelial Cells/drug effects ; Epithelial Cells/enzymology ; Female ; Gluconeogenesis/genetics ; Intestines/drug effects ; Intestines/enzymology ; Monocarboxylic Acid Transporters/genetics ; Phosphoenolpyruvate Carboxykinase (ATP)/genetics ; Pyruvate Carboxylase/genetics ; RNA, Messenger/genetics ; Sodium-Hydrogen Exchanger 1/genetics
Czasopismo naukowe
Tytuł :
Substrate-dependent CO2 fixation in heterotrophic bacteria revealed by stable isotope labelling.
Autorzy :
Spona-Friedl M; Institute of Groundwater Ecology, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
Braun A; Institute of Groundwater Ecology, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
Huber C; Chair of Biochemistry, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany.
Eisenreich W; Chair of Biochemistry, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany.
Griebler C; Institute of Groundwater Ecology, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.; Department of Functional and Evolutionary Ecology, Universität Wien, Althanstr. 14, A-1090 Wien, Austria.
Kappler A; Geomicrobiology, Eberhard-Karls-University Tuebingen, Sigwartstr. 10, 72076 Tuebingen, Germany.
Elsner M; Institute of Groundwater Ecology, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.; Chair of Analytical Chemistry and Water Chemistry, Technische Universität München, Marchioninistr. 17, 81377 München, Germany.
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Źródło :
FEMS microbiology ecology [FEMS Microbiol Ecol] 2020 Jun 01; Vol. 96 (6).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbon Dioxide*
Gluconeogenesis*
Bacteria ; Carbon Isotopes ; Isotope Labeling
Czasopismo naukowe
Tytuł :
Long-term exposure to low doses of bisphenol S has hypoglycaemic effect in adult male mice by promoting insulin sensitivity and repressing gluconeogenesis.
Autorzy :
Guo Y; The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518033, China.
Lv Z; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Tang Z; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China; Department of Environmental and Occupational Health, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Huang S; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Peng C; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Wang F; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Zhou Z; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Ding W; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Liu W; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Liu P; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Li D; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Song J; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
He J; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Chen Y; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Liu G; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Hu X; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Liu J; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
Ke Y; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2021 May 15; Vol. 277, pp. 116630. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article
MeSH Terms :
Insulin Resistance*
Animals ; Benzhydryl Compounds/toxicity ; Gluconeogenesis ; Hypoglycemic Agents ; Male ; Mice ; Phenols ; Sulfones
Czasopismo naukowe
Tytuł :
Carbohydrate metabolism in trypanosomatids: New insights revealing novel complexity, diversity and species-unique features.
Autorzy :
Michels PAM; Centre for Immunity, Infection and Evolution and Centre for Translational and Chemical Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, United Kingdom. Electronic address: .
Villafraz O; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, France.
Pineda E; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, France.
Alencar MB; Laboratory of Biochemistry of Tryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, 05508-000, Brazil.
Cáceres AJ; Laboratorio de Enzimología de Parásitos, Departamento de Biología, Facultad de Ciencias, Universidad de Los Andes, Mérida, 5101, Venezuela. Electronic address: .
Silber AM; Laboratory of Biochemistry of Tryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, 05508-000, Brazil. Electronic address: .
Bringaud F; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, France. Electronic address: .
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Źródło :
Experimental parasitology [Exp Parasitol] 2021 May; Vol. 224, pp. 108102. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carbohydrate Metabolism/*physiology
Trypanosomatina/*metabolism
Energy Metabolism ; Galactose/metabolism ; Gluconeogenesis/physiology ; Glycolysis/physiology ; Trypanosomatina/enzymology
Czasopismo naukowe
Tytuł :
The Metformin Mechanism on Gluconeogenesis and AMPK Activation: The Metabolite Perspective.
Autorzy :
Agius L; Biosciences Institute, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Ford BE; Biosciences Institute, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Chachra SS; Biosciences Institute, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 May 03; Vol. 21 (9). Date of Electronic Publication: 2020 May 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gluconeogenesis*
Hypoglycemic Agents/*pharmacology
Liver/*metabolism
Metformin/*pharmacology
Protein Kinases/*metabolism
Animals ; Glycolysis ; Humans ; Liver/drug effects
Czasopismo naukowe
Tytuł :
Hypoxia increases the rate of renal gluconeogenesis via hypoxia-inducible factor-1-dependent activation of phosphoenolpyruvate carboxykinase expression.
Autorzy :
Owczarek A; Department of Metabolic Regulation, Institute of Biochemistry, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096, Warsaw, Poland.
Gieczewska K; Department of Plant Anatomy and Cytology, Institute of Experimental Plant Biology and Biotechnology, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096, Warsaw, Poland.
Jarzyna R; Department of Metabolic Regulation, Institute of Biochemistry, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096, Warsaw, Poland.
Jagielski AK; Department of Metabolic Regulation, Institute of Biochemistry, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096, Warsaw, Poland.
Kiersztan A; Department of Metabolic Regulation, Institute of Biochemistry, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096, Warsaw, Poland.
Gruza A; Department of Metabolic Regulation, Institute of Biochemistry, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096, Warsaw, Poland.
Winiarska K; Department of Metabolic Regulation, Institute of Biochemistry, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096, Warsaw, Poland. Electronic address: .
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Źródło :
Biochimie [Biochimie] 2020 Apr - May; Vol. 171-172, pp. 31-37. Date of Electronic Publication: 2020 Feb 08.
Typ publikacji :
Journal Article
MeSH Terms :
Gluconeogenesis*
Glucose/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*physiology
Intracellular Signaling Peptides and Proteins/*metabolism
Kidney/*metabolism
Phosphoenolpyruvate Carboxykinase (ATP)/*metabolism
Phosphoenolpyruvate Carboxykinase (GTP)/*metabolism
Cell Hypoxia ; Cell Line ; Gene Expression Regulation, Enzymologic ; Humans
Czasopismo naukowe
Tytuł :
Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia.
Autorzy :
Chattopadhyay T; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005 Maharashtra, India.
Maniyadath B; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005 Maharashtra, India.
Bagul HP; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005 Maharashtra, India.
Chakraborty A; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005 Maharashtra, India.
Shukla N; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005 Maharashtra, India.
Budnar S; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005 Maharashtra, India.
Rajendran A; Department of Biology, Indian Institute of Science Education and Research, Pune, 411008 Maharashtra, India.
Shukla A; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005 Maharashtra, India.
Kamat SS; Department of Biology, Indian Institute of Science Education and Research, Pune, 411008 Maharashtra, India.
Kolthur-Seetharam U; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005 Maharashtra, India; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Mar 24; Vol. 117 (12), pp. 6890-6900. Date of Electronic Publication: 2020 Mar 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gluconeogenesis*
Homeostasis*
Protein Processing, Post-Translational*
Hyperglycemia/*prevention & control
Liver/*metabolism
Sirtuin 1/*metabolism
Acetylglucosamine/metabolism ; Aging/physiology ; Animals ; Fasting ; Glycosylation ; HEK293 Cells ; Humans ; Hyperglycemia/metabolism ; Hyperglycemia/pathology ; Insulin Resistance ; Liver/immunology ; Liver/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/metabolism ; Obesity/pathology ; Obesity/prevention & control ; Phosphorylation ; Sirtuin 1/chemistry ; Spatio-Temporal Analysis
Czasopismo naukowe
Tytuł :
Hepatic glycerol metabolism is early reprogrammed in rat liver cancer development.
Autorzy :
Lorenzetti F; Instituto de Fisiología Experimental (IFISE), Facultad de Ciencias Bioquímicas y Farmacéuticas, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Rosario (UNR), Suipacha 570, S2002LRL, Rosario, Argentina. Electronic address: .
Capiglioni AM; Instituto de Fisiología Experimental (IFISE), Facultad de Ciencias Bioquímicas y Farmacéuticas, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Rosario (UNR), Suipacha 570, S2002LRL, Rosario, Argentina. Electronic address: .
Marinelli RA; Instituto de Fisiología Experimental (IFISE), Facultad de Ciencias Bioquímicas y Farmacéuticas, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Rosario (UNR), Suipacha 570, S2002LRL, Rosario, Argentina. Electronic address: .
Carrillo MC; Área Morfología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Argentina. Electronic address: .
Alvarez ML; Área Morfología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Argentina; Universidad Abierta Interamericana - Centro de Altos Estudios en Ciencias Humanas y de la Salud, Argentina. Electronic address: .
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Źródło :
Biochimie [Biochimie] 2020 Mar; Vol. 170, pp. 88-93. Date of Electronic Publication: 2020 Jan 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gluconeogenesis*
Aquaporins/*metabolism
Glucose/*metabolism
Glycerol/*metabolism
Liver/*pathology
Liver Neoplasms/*pathology
Animals ; Glycerol Kinase/metabolism ; Glycerolphosphate Dehydrogenase/metabolism ; Liver/metabolism ; Liver Neoplasms/metabolism ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Exogenous GLP-1 stimulates TCA cycle and suppresses gluconeogenesis and ketogenesis in late-fasted northern elephant seals pups.
Autorzy :
Dhillon J; Department of Molecular & Cell Biology, School of Natural Sciences, University of California, Merced, California.; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.
Viscarra JA; Department of Molecular & Cell Biology, School of Natural Sciences, University of California, Merced, California.; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California.
Newman JW; Obesity and Metabolism Research Unit, USDA Agricultural Research Service Western Human Nutrition Research Center, University of California, Davis, California.; NIH West Coast Metabolomics Center, University of California, Davis, California.
Fiehn O; NIH West Coast Metabolomics Center, University of California, Davis, California.
Crocker DE; Department of Biology, Sonoma State University, Rohnert Park, California.
Ortiz RM; Department of Molecular & Cell Biology, School of Natural Sciences, University of California, Merced, California.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2021 Apr 01; Vol. 320 (4), pp. R393-R403. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Blood Glucose/*drug effects
Citric Acid Cycle/*drug effects
Glucagon-Like Peptide 1/*administration & dosage
Gluconeogenesis/*drug effects
Ketone Bodies/*metabolism
Seals, Earless/*metabolism
Animals ; Biomarkers/blood ; Blood Glucose/metabolism ; Dose-Response Relationship, Drug ; Fasting/blood ; Infusions, Intravenous ; Male ; Metabolome ; Metabolomics ; Seals, Earless/blood ; Time Factors ; Weaning
Czasopismo naukowe
Tytuł :
Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver.
Autorzy :
Deja S; Center for Human Nutrition, The University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Fu X; Center for Human Nutrition, The University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Fletcher JA; Center for Human Nutrition, The University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Kucejova B; Center for Human Nutrition, The University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Browning JD; Department of Clinical Nutrition, The University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Young JD; Department of Chemical and Biomolecular Engineering, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37235, USA. Electronic address: .
Burgess SC; Center for Human Nutrition, The University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Electronic address: .
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Źródło :
Metabolic engineering [Metab Eng] 2020 May; Vol. 59, pp. 1-14. Date of Electronic Publication: 2019 Dec 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Citric Acid Cycle*
Gluconeogenesis*
Models, Biological*
Pentose Phosphate Pathway*
Liver/*metabolism
Animals ; Carbon Isotopes/analysis ; Carbon Isotopes/chemistry ; Carbon Isotopes/pharmacology ; Male ; Mice ; Nuclear Magnetic Resonance, Biomolecular
Czasopismo naukowe
Tytuł :
Metabolism of Gluconeogenic Substrates by an Intracellular Fungal Pathogen Circumvents Nutritional Limitations within Macrophages.
Autorzy :
Shen Q; Department of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Ray SC; Department of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Evans HM; Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Deepe GS Jr; Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Rappleye CA; Department of Microbiology, The Ohio State University, Columbus, Ohio, USA .
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Źródło :
MBio [mBio] 2020 Apr 07; Vol. 11 (2). Date of Electronic Publication: 2020 Apr 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gluconeogenesis*
Metabolic Networks and Pathways*
Histoplasma/*metabolism
Macrophages/*microbiology
Phagosomes/*microbiology
Animals ; Cell Line ; Fungal Proteins/metabolism ; Gene Expression Profiling ; Glycolysis ; Histoplasma/growth & development ; Histoplasma/pathogenicity ; Histoplasmosis/microbiology ; Lung/microbiology ; Macrophages/chemistry ; Metabolomics ; Mice ; Mice, Inbred C57BL ; Phagosomes/chemistry ; Virulence
Czasopismo naukowe

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