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Wyszukujesz frazę ""Glutamine"" wg kryterium: Temat


Tytuł:
Astrocyte-Neuron Interaction via the Glutamate-Glutamine Cycle and Its Dysfunction in Tau-Dependent Neurodegeneration.
Autorzy:
Sidoryk-Węgrzynowicz M; Laboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawińskiego Str., 02-106 Warsaw, Poland.
Adamiak K; Laboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawińskiego Str., 02-106 Warsaw, Poland.
Strużyńska L; Laboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawińskiego Str., 02-106 Warsaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Astrocytes*/metabolism
Glutamic Acid*/metabolism
Glutamine*/metabolism
Neurodegenerative Diseases*/metabolism
Neurons*/metabolism
Humans ; Blood-Brain Barrier/metabolism ; Cell Communication
Czasopismo naukowe
Tytuł:
The role of glutamate and glutamine metabolism and related transporters in nerve cells.
Autorzy:
Zhang D; Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.; Medical Research Center, Liaoning Key Laboratory of Research and Application of Animal Models for Environment and Metabolic Diseases, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Hua Z; Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.; Medical Research Center, Liaoning Key Laboratory of Research and Application of Animal Models for Environment and Metabolic Diseases, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Li Z; Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.; Medical Research Center, Liaoning Key Laboratory of Research and Application of Animal Models for Environment and Metabolic Diseases, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14617.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Glutamic Acid*/metabolism
Glutamine*
Amino Acids/metabolism ; Brain/metabolism ; Neurons/metabolism
Czasopismo naukowe
Tytuł:
Suppressive effect of Yokukansan on glutamate released from canine keratinocytes.
Autorzy:
Kasuga Y; Department of Dermatology and Allergology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hu A; Center for Advanced Kampo Medicine and Clinical Research, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kawakami Z; Center for Advanced Kampo Medicine and Clinical Research, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tabuchi M; Center for Advanced Kampo Medicine and Clinical Research, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yamaguchi T; Center for Advanced Kampo Medicine and Clinical Research, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kobayashi H; Center for Advanced Kampo Medicine and Clinical Research, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ikeda S; Department of Dermatology and Allergology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
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Źródło:
Open veterinary journal [Open Vet J] 2024 Feb; Vol. 14 (2), pp. 683-691. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Glutamic Acid*/pharmacology
Glutamine*/pharmacology
Drugs, Chinese Herbal*
Mice ; Animals ; Dogs ; Dizocilpine Maleate/pharmacology ; Glutamate Dehydrogenase/pharmacology ; Keratinocytes ; Radioisotopes/pharmacology
Czasopismo naukowe
Tytuł:
The Role of Glutamine Homeostasis in Emotional and Cognitive Functions.
Autorzy:
Baek JH; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-Aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, 15 Jinju-daero 816 Beongil, Jinju 52727, Gyeongnam, Republic of Korea.
Park H; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-Aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, 15 Jinju-daero 816 Beongil, Jinju 52727, Gyeongnam, Republic of Korea.
Kang H; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-Aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, 15 Jinju-daero 816 Beongil, Jinju 52727, Gyeongnam, Republic of Korea.
Kim R; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-Aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, 15 Jinju-daero 816 Beongil, Jinju 52727, Gyeongnam, Republic of Korea.
Kang JS; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-Aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, 15 Jinju-daero 816 Beongil, Jinju 52727, Gyeongnam, Republic of Korea.
Kim HJ; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-Aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, 15 Jinju-daero 816 Beongil, Jinju 52727, Gyeongnam, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 21; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Glutamine*/metabolism
Glutamic Acid*/metabolism
Astrocytes/metabolism ; Neurons/metabolism ; Cognition
Czasopismo naukowe
Tytuł:
Supplementation of mixed doses of glutamate and glutamine can improve the growth and gut health of piglets during the first 2 weeks post-weaning.
Autorzy:
Luise D; DISTAL, University of Bologna, Viale G. Fanin 44, 40127, Bologna, Italy.
Correa F; DISTAL, University of Bologna, Viale G. Fanin 44, 40127, Bologna, Italy.
Chalvon-Demersay T; Metex Noovistago, 32 rue Guersant, 75017, Paris, France.
Galosi L; School of Biosciences and Veterinary Medicine, University of Camerino, 62024, Matelica, Italy.
Rossi G; School of Biosciences and Veterinary Medicine, University of Camerino, 62024, Matelica, Italy.
Lambert W; Metex Noovistago, 32 rue Guersant, 75017, Paris, France.
Bosi P; DISTAL, University of Bologna, Viale G. Fanin 44, 40127, Bologna, Italy.
Trevisi P; DISTAL, University of Bologna, Viale G. Fanin 44, 40127, Bologna, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 25; Vol. 12 (1), pp. 14533. Date of Electronic Publication: 2022 Aug 25.
Typ publikacji:
Journal Article
MeSH Terms:
Glutamic Acid*
Glutamine*/metabolism
Animal Feed/analysis ; Animals ; Diet ; Dietary Supplements ; Swine ; Weaning
Czasopismo naukowe
Tytuł:
Detection of C labeling of glutamate and glutamine in human brain by proton magnetic resonance spectroscopy.
Autorzy:
An L; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 3D46, 10 Center Drive, MSC 1216, Bethesda, MD, 20892-1216, USA. .
Li S; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 3D46, 10 Center Drive, MSC 1216, Bethesda, MD, 20892-1216, USA.
Ferraris Araneta M; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 3D46, 10 Center Drive, MSC 1216, Bethesda, MD, 20892-1216, USA.
Johnson CS; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 3D46, 10 Center Drive, MSC 1216, Bethesda, MD, 20892-1216, USA.
Shen J; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 3D46, 10 Center Drive, MSC 1216, Bethesda, MD, 20892-1216, USA.
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Źródło:
Scientific reports [Sci Rep] 2022 May 24; Vol. 12 (1), pp. 8729. Date of Electronic Publication: 2022 May 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Glutamic Acid*
Glutamine*
Brain/diagnostic imaging ; Gyrus Cinguli/diagnostic imaging ; Humans ; Magnetic Resonance Spectroscopy/methods ; Proton Magnetic Resonance Spectroscopy/methods
Czasopismo naukowe
Tytuł:
High-fat and combined high-fat-high-fructose diets impair episodic-like memory and decrease glutamate and glutamine in the hippocampus of adult mice.
Autorzy:
Martínez-Orozco H; Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, México.
Reyes-Castro LA; Departamento de Biología de la Reproducción, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Lomas-Soria C; CONACYT Cátedras, Departamento de Biología de la Reproducción, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Sandoval-Salazar C; Departamento de Enfermería y Obstetricia, División de Ciencias de la Salud e Ingenierías, Campus Celaya-Salvatierra, Universidad de Guanajuato, Celaya, México.
Ramírez-Emiliano J; Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, México.
Díaz-Cintra S; Laboratorio de Neuromorfometría y Desarrollo, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
Solís-Ortiz S; Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, México.
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Źródło:
Nutritional neuroscience [Nutr Neurosci] 2022 Dec; Vol. 25 (12), pp. 2479-2489. Date of Electronic Publication: 2021 Oct 30.
Typ publikacji:
Journal Article
MeSH Terms:
Diet, High-Fat*/adverse effects
Glutamic Acid*/metabolism
Humans ; Animals ; Mice ; Glutamine ; Fructose/adverse effects ; Mice, Inbred C57BL ; Hippocampus/metabolism ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Tytuł:
Human placental uptake of glutamine and glutamate is reduced in fetal growth restriction.
Autorzy:
McIntyre KR; Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. .; Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK. .; School of Medicine, Dentistry and Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Wolfson Medical School Building, University Avenue, Glasgow, G12 8QQ, UK. .
Vincent KMM; Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Hayward CE; Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Li X; Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Sibley CP; Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Desforges M; Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Greenwood SL; Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Dilworth MR; Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
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Źródło:
Scientific reports [Sci Rep] 2020 Oct 01; Vol. 10 (1), pp. 16197. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fetal Development*
Carbon Radioisotopes/*analysis
Fetal Growth Retardation/*epidemiology
Glutamic Acid/*metabolism
Glutamine/*metabolism
Infant, Small for Gestational Age/*metabolism
Placenta/*metabolism
Adolescent ; Adult ; Amino Acid Transport System X-AG/metabolism ; Birth Weight ; Female ; Fetal Growth Retardation/metabolism ; Fetal Growth Retardation/pathology ; Gestational Age ; Glutamic Acid/analysis ; Glutamine/analysis ; Humans ; Infant, Newborn ; Pregnancy ; Pregnancy Proteins/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Young Adult
Czasopismo naukowe
Tytuł:
"Glu/GABA-Gln" metabolic loop abnormalities in iminodipropionitrile (IDPN)-induced dyskinetic syndrome.
Autorzy:
Hao J; School of Medicine, Shaoxing University, 900 Chengnan Road, Shaoxing, 312000, People's Republic of China.; Xin Hua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, People's Republic of China.
Jiang K; Xin Hua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, People's Republic of China.
Zhang X; Xin Hua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, People's Republic of China.
Wu M; Xin Hua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, People's Republic of China. .
Ma B; Xin Hua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, People's Republic of China. .
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 Nov; Vol. 42 (11), pp. 4697-4706. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji:
Journal Article
MeSH Terms:
Dyskinesias*
Glutamic Acid*
Animals ; Glutamine ; Male ; Rats ; Rats, Wistar ; gamma-Aminobutyric Acid
Czasopismo naukowe
Tytuł:
Are there differences in the biochemical profile of bilateral normal testes? A 3.0 T 1H-MR spectroscopy study.
Autorzy:
Tsili AC; Department of Clinical Radiology, School of Health Sciences, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
Astrakas LG; Department of Medical Physics, School of Health Sciences, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
Sofikitis N; Department of Urology, School of Health Sciences, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
Argyropoulou MI; Department of Clinical Radiology, School of Health Sciences, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
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Źródło:
Andrologia [Andrologia] 2020 Jun; Vol. 52 (5), pp. e13569. Date of Electronic Publication: 2020 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Glutamic Acid/*analysis
Glutamine/*analysis
Lactic Acid/*analysis
Testis/*chemistry
Adolescent ; Adult ; Creatine/analysis ; Creatine/metabolism ; Glutamic Acid/metabolism ; Glutamine/metabolism ; Humans ; Lactic Acid/metabolism ; Male ; Middle Aged ; Proton Magnetic Resonance Spectroscopy ; Retrospective Studies ; Testis/anatomy & histology ; Testis/metabolism ; Young Adult
Czasopismo naukowe
Tytuł:
Analysis of low-molecular-weight metabolites in stomach cancer cells by a simplified and inexpensive GC/MS metabolomics method.
Autorzy:
Dai M; College of Chemistry, Zhengzhou University, 75 University Road, Zhengzhou, 450052, Henan, China.
Ma T; School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, Henan, China.
Niu Y; College of Chemistry, Zhengzhou University, 75 University Road, Zhengzhou, 450052, Henan, China.
Zhang M; College of Chemistry, Zhengzhou University, 75 University Road, Zhengzhou, 450052, Henan, China.
Zhu Z; College of Chemistry, Zhengzhou University, 75 University Road, Zhengzhou, 450052, Henan, China.
Wang S; College of Chemistry, Zhengzhou University, 75 University Road, Zhengzhou, 450052, Henan, China. .
Liu H; School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, Henan, China.
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2020 May; Vol. 412 (12), pp. 2981-2991. Date of Electronic Publication: 2020 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Gas Chromatography-Mass Spectrometry/*methods
Glutamic Acid/*analysis
Glutamine/*analysis
Metabolomics/*methods
Stomach Neoplasms/*metabolism
Stomach Neoplasms/*pathology
Glutamic Acid/metabolism ; Glutamine/metabolism ; Humans ; Molecular Weight ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
The relationship between measurement of in vivo brain glutamate and markers of iron metabolism: A proton magnetic resonance spectroscopy study in healthy adults.
Autorzy:
Burger A; Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
Kotze MJ; Division of Chemical Pathology, Department of Pathology, Stellenbosch University, Cape Town, South Africa.
Stein DJ; Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.; SU/UCT MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
Janse van Rensburg S; Division of Chemical Pathology, Department of Pathology, Stellenbosch University, Cape Town, South Africa.
Howells FM; Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2020 Feb; Vol. 51 (4), pp. 984-990. Date of Electronic Publication: 2019 Oct 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glutamic Acid*
Glutamine*
Adult ; Biomarkers ; Brain/diagnostic imaging ; Female ; Humans ; Iron ; Magnetic Resonance Imaging ; Male ; Proton Magnetic Resonance Spectroscopy
Czasopismo naukowe
Tytuł:
Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose.
Autorzy:
Pawlik MJ; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Aldana BI; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
Belfiori-Carrasco LF; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
Obara-Michlewska M; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Popek MP; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Czarnecka AM; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Albrecht J; Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 15; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:
Journal Article
MeSH Terms:
Seizures*/chemically induced
Seizures*/drug therapy
Seizures*/metabolism
Seizures*/pathology
Brain/*drug effects
Glutamic Acid/*metabolism
Glutamine/*metabolism
Methionine Sulfoximine/*pharmacology
Animals ; Brain/metabolism ; Disease Progression ; Dose-Response Relationship, Drug ; Lithium/adverse effects ; Male ; Methionine Sulfoximine/administration & dosage ; Pilocarpine/adverse effects ; Rats ; Rats, Sprague-Dawley ; Secretory Pathway/drug effects
Czasopismo naukowe
Tytuł:
Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice.
Autorzy:
Chen YP; a School of Pharmaceutical Sciences , Southern Medical University , Guangzhou , PR China.; b College of Pharmacy , Fujian University of Traditional Chinese Medicine , Fuzhou , PR China.
Wang C; c Ningbo Key Laboratory of Behavioral Neuroscience , Ningbo University School of Medicine , Ningbo , PR China.
Xu JP; a School of Pharmaceutical Sciences , Southern Medical University , Guangzhou , PR China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2019 Dec; Vol. 57 (1), pp. 280-286.
Typ publikacji:
Journal Article
MeSH Terms:
Behavior, Animal*
Brain/*metabolism
Depression/*metabolism
Glutamic Acid/*blood
Glutamine/*blood
Stress, Psychological/*metabolism
Animals ; Depression/blood ; Depression/psychology ; Disease Models, Animal ; Glutamic Acid/metabolism ; Glutamine/metabolism ; Male ; Mice, Inbred Strains
Czasopismo naukowe
Tytuł:
Brain neurochemistry in unmedicated obsessive-compulsive disorder patients and effects of 12-week escitalopram treatment: H-magnetic resonance spectroscopy study.
Autorzy:
Parmar A; National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India.
Sharan P; Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
Khandelwal SK; Department of Psychiatry, Holy Family Hospital, New Delhi, India.
Agarwal K; Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India.
Sharma U; Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India.
Jagannathan NR; Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India.
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Źródło:
Psychiatry and clinical neurosciences [Psychiatry Clin Neurosci] 2019 Jul; Vol. 73 (7), pp. 386-393. Date of Electronic Publication: 2019 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Caudate Nucleus*/diagnostic imaging
Caudate Nucleus*/drug effects
Caudate Nucleus*/metabolism
Gyrus Cinguli*/drug effects
Gyrus Cinguli*/metabolism
Thalamus*/diagnostic imaging
Thalamus*/drug effects
Thalamus*/metabolism
Choline/*metabolism
Citalopram/*pharmacology
Glutamic Acid/*metabolism
Glutamine/*metabolism
Inositol/*metabolism
Obsessive-Compulsive Disorder/*drug therapy
Obsessive-Compulsive Disorder/*metabolism
Selective Serotonin Reuptake Inhibitors/*pharmacology
Adolescent ; Adult ; Case-Control Studies ; Citalopram/administration & dosage ; Female ; Follow-Up Studies ; Glutamic Acid/drug effects ; Glutamine/drug effects ; Humans ; Male ; Middle Aged ; Obsessive-Compulsive Disorder/diagnostic imaging ; Obsessive-Compulsive Disorder/physiopathology ; Proton Magnetic Resonance Spectroscopy ; Selective Serotonin Reuptake Inhibitors/administration & dosage ; Severity of Illness Index ; Young Adult
Czasopismo naukowe
Tytuł:
Glutamate is an essential mediator in glutamine-amplified insulin secretion.
Autorzy:
Han G; Division of Metabolism and Disease, Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan.; Division of Molecular and Metabolic Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan.; Kansai Electric Power Medical Research Institute, Kobe, Japan.
Takahashi H; Division of Molecular and Metabolic Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan.
Murao N; Division of Molecular and Metabolic Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan.
Gheni G; Division of Molecular and Metabolic Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan.
Yokoi N; Division of Molecular and Metabolic Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan.; Laboratory of Animal Breeding and Genetics, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Hamamoto Y; Kansai Electric Power Medical Research Institute, Kobe, Japan.
Asahara SI; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Seino Y; Kansai Electric Power Medical Research Institute, Kobe, Japan.
Kido Y; Division of Metabolism and Disease, Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan.; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Seino S; Division of Molecular and Metabolic Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan.
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Źródło:
Journal of diabetes investigation [J Diabetes Investig] 2021 Jun; Vol. 12 (6), pp. 920-930. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Glutamic Acid/*metabolism
Glutamine/*metabolism
Insulin Secretion/*physiology
Insulin-Secreting Cells/*metabolism
Animals ; Aspartate Aminotransferase, Cytoplasmic ; Cells, Cultured ; Glucose/metabolism ; Glutamate Dehydrogenase ; Insulin/metabolism ; Islets of Langerhans/cytology ; Mice ; Signal Transduction
Czasopismo naukowe
Tytuł:
N-acetylcysteine reduces cocaine-seeking behavior and anterior cingulate glutamate/glutamine levels among cocaine-dependent individuals.
Autorzy:
Woodcock EA; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Lundahl LH; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Khatib D; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Stanley JA; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Greenwald MK; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
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Źródło:
Addiction biology [Addict Biol] 2021 Mar; Vol. 26 (2), pp. e12900. Date of Electronic Publication: 2020 Mar 24.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcysteine/*therapeutic use
Cocaine-Related Disorders/*drug therapy
Drug-Seeking Behavior/*drug effects
Glutamic Acid/*drug effects
Glutamine/*drug effects
Gyrus Cinguli/*drug effects
Acetylcysteine/pharmacology ; Adult ; Cross-Over Studies ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Proton Magnetic Resonance Spectroscopy ; Reward
Czasopismo naukowe
Tytuł:
The glutamine-glutamate cycle regulates synaptic glutamate release in the ventrolateral ventromedial nucleus of the hypothalamus of perinatal female rats.
Autorzy:
Liang SL; Department of Physiology and Pharmacology, College of Medicine, Chang Gung University, Linkou, Tao-Yuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital, Linkou, Tao-Yuan, Taiwan.
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Źródło:
Journal of neuroendocrinology [J Neuroendocrinol] 2018 Nov; Vol. 30 (11), pp. e12642. Date of Electronic Publication: 2018 Oct 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Astrocytes/*metabolism
Glutamic Acid/*metabolism
Glutamine/*metabolism
Neurons/*physiology
Ventromedial Hypothalamic Nucleus/*metabolism
Animals ; Astrocytes/drug effects ; Excitatory Postsynaptic Potentials ; Female ; Glutamine/administration & dosage ; Hypothalamus, Middle/drug effects ; Hypothalamus, Middle/metabolism ; Male ; Miniature Postsynaptic Potentials ; Neurons/drug effects ; Rats, Sprague-Dawley ; Receptors, AMPA/metabolism ; Sex Characteristics ; Ventromedial Hypothalamic Nucleus/drug effects ; beta-Alanine/administration & dosage ; beta-Alanine/analogs & derivatives
Czasopismo naukowe
Tytuł:
Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine-Glutamate Cycle.
Autorzy:
Gandasi NR; Department of Metabolic Physiology, Institute of Neuroscience and Physiology, University of Göteborg, Box 430, SE-405 30 Göteborg, Sweden.
Arapi V; Department of Pharmaceutical Biosciences, Molecular Neuropharmacology, Uppsala University, SE-751 23 Uppsala, Sweden.
Mickael ME; Department of Neuroscience, Functional Pharmacology, Uppsala University, SE-751 23 Uppsala, Sweden.; Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, ul. Postepu 36A, Jastrzębiec, PL05 552 Magdalenka, Poland.
Belekar PA; Department of Metabolic Physiology, Institute of Neuroscience and Physiology, University of Göteborg, Box 430, SE-405 30 Göteborg, Sweden.
Granlund L; Department of Pharmaceutical Biosciences, Molecular Neuropharmacology, Uppsala University, SE-751 23 Uppsala, Sweden.
Kothegala L; Department of Metabolic Physiology, Institute of Neuroscience and Physiology, University of Göteborg, Box 430, SE-405 30 Göteborg, Sweden.
Fredriksson R; Department of Pharmaceutical Biosciences, Molecular Neuropharmacology, Uppsala University, SE-751 23 Uppsala, Sweden.
Bagchi S; Department of Pharmaceutical Biosciences, Molecular Neuropharmacology, Uppsala University, SE-751 23 Uppsala, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 25; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Amino Acid Transport Systems, Neutral/*metabolism
Caveolins/*metabolism
Glutamic Acid/*metabolism
Glutamine/*metabolism
Nerve Tissue Proteins/*metabolism
Amino Acid Transport Systems, Neutral/chemistry ; Amino Acid Transport Systems, Neutral/genetics ; Animals ; Caveolins/chemistry ; Cell Line ; Gene Expression Regulation ; Gene Knockdown Techniques ; Immunohistochemistry ; Mice ; Models, Biological ; Models, Molecular ; Nerve Tissue Proteins/chemistry ; Nerve Tissue Proteins/genetics ; Protein Binding ; Protein Conformation ; Protein Interaction Domains and Motifs ; Protein Transport ; RNA, Small Interfering/genetics ; Signal Transduction ; Sodium/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Cerebral dopaminergic and glutamatergic transmission relate to different subjective responses of acute alcohol intake: an in vivo multimodal imaging study.
Autorzy:
Leurquin-Sterk G; Department of Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, University Hospitals Leuven, Belgium.
Ceccarini J; Department of Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, University Hospitals Leuven, Belgium.
Crunelle CL; Toxicological Center, University of Antwerp, Department of Psychiatry, University Hospital Brussels, Belgium.
Weerasekera A; Department of Imaging and Pathology, Biomedical MRI/MoSAIC, Belgium.
de Laat B; Department of Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, University Hospitals Leuven, Belgium.; MoSAIC, Molecular Small Animal Imaging Center, Belgium.
Himmelreich U; Department of Imaging and Pathology, Biomedical MRI/MoSAIC, Belgium.
Bormans G; Laboratory for Radiopharmacy, Belgium.
Van Laere K; Department of Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, University Hospitals Leuven, Belgium.; MoSAIC, Molecular Small Animal Imaging Center, Belgium.
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Źródło:
Addiction biology [Addict Biol] 2018 May; Vol. 23 (3), pp. 931-944. Date of Electronic Publication: 2017 Sep 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain/*drug effects
Central Nervous System Depressants/*pharmacology
Dopamine/*metabolism
Ethanol/*pharmacology
Glutamic Acid/*drug effects
Glutamine/*drug effects
Receptor, Metabotropic Glutamate 5/*drug effects
Synaptic Transmission/*drug effects
Adult ; Benzamides ; Brain/diagnostic imaging ; Brain/metabolism ; Caudate Nucleus/diagnostic imaging ; Caudate Nucleus/drug effects ; Caudate Nucleus/metabolism ; Female ; Glutamic Acid/metabolism ; Glutamine/metabolism ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Nitriles ; Parietal Lobe ; Positron-Emission Tomography ; Prefrontal Cortex/diagnostic imaging ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/metabolism ; Proton Magnetic Resonance Spectroscopy ; Pyridines ; Pyrrolidines ; Radiopharmaceuticals ; Receptor, Metabotropic Glutamate 5/metabolism ; Temporal Lobe/diagnostic imaging ; Temporal Lobe/drug effects ; Temporal Lobe/metabolism ; Thalamus/diagnostic imaging ; Thalamus/drug effects ; Thalamus/metabolism ; Young Adult
Czasopismo naukowe

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