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Tytuł:
Molecular Docking Studies and the Effect of Fluorophenylthiourea Derivatives on Glutathione-Dependent Enzymes.
Autorzy:
Demir Y; Department of Pharmacy Services, Nihat Delibalta Göle Vocational High School, Ardahan University, Ardahan, 75700, Turkey.
Türkeş C; Department of Biochemistry, Faculty of Pharmacy, Erzincan Binali Yıldırım University, Erzincan, 24100, Turkey.
Küfrevioğlu Öİ; Department of Chemistry, Faculty of Science, Atatürk University, Erzurum, 25240, Turkey.
Beydemir Ş; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, 26470, Turkey.; The Rectorate of Bilecik Şeyh Edebali University, Bilecik, 11230, Turkey.
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Źródło:
Chemistry & biodiversity [Chem Biodivers] 2023 Jan; Vol. 20 (1), pp. e202200656. Date of Electronic Publication: 2022 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione Transferase*
Glutathione*/metabolism
Humans ; Molecular Docking Simulation ; Antioxidants/metabolism ; Oxidative Stress ; Glutathione Reductase/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Automated approach for the evaluation of glutathione-S-transferase P1-1 inhibition by organometallic anticancer compounds.
Autorzy:
Pereira SAP; LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.
Baptista L AC; LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.
Biancalana L; Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italy.
Marchetti F; Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italy.
Dyson PJ; Institut des Sciences et Ingénierie Chimiques, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Saraiva MLMFS; LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1527-1536.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione Transferase*
Organometallic Compounds*/pharmacology
Glutathione ; Glutathione S-Transferase pi ; Iridium
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Suppression of glutathione system and upregulation of caspase 3-dependent apoptosis mediate rohypnol-induced gastric injury.
Autorzy:
Akhigbe RE; Reproductive Physiology and Bioinformatics Research Unit, Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.; Reproductive Biology and Toxicology Research Laboratories, Oasis of Grace Hospital, Osogbo, Nigeria.
Oluwole DT; Reproductive Physiology and Bioinformatics Research Unit, Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
Adegoke TE; Department of Physiology, Joseph Ayo Babalola University, Arakeji, Nigeria.
Hamed MA; Reproductive Biology and Toxicology Research Laboratories, Oasis of Grace Hospital, Osogbo, Nigeria.; Brainwill Laboratories and Biomedical Services, Osogbo, Nigeria.
Anyogu DC; Department of Veterinary Pathology and Microbiology, University of Nigeria, Nsukka, Nigeria.
Ajayi AF; Reproductive Physiology and Bioinformatics Research Unit, Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
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Źródło:
Redox report : communications in free radical research [Redox Rep] 2022 Dec; Vol. 27 (1), pp. 111-118.
Typ publikacji:
Journal Article
MeSH Terms:
Flunitrazepam*
Glutathione*/metabolism
Animals ; Apoptosis ; Caspase 3/metabolism ; Cyclooxygenase 2/genetics ; Glutathione Disulfide ; Glutathione Peroxidase/metabolism ; Male ; Oxidative Stress ; Rats ; Rats, Wistar ; Superoxide Dismutase/metabolism ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Parkin coregulates glutathione metabolism in adult mammalian brain.
Autorzy:
El Kodsi DN; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
Tokarew JM; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
Sengupta R; Department of Biochemistry, Karolinska Institute, Stockholm, Sweden.; Amity Institute of Biotechnology, Amity University, Kolkata, West Bengal, India.
Lengacher NA; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
Chatterji A; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
Nguyen AP; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.; Snyder Institute, University of Calgary, Calgary, AB, Canada.
Boston H; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Jiang Q; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Palmberg C; Department of Biochemistry, Karolinska Institute, Stockholm, Sweden.
Pileggi C; Department of Biochemistry, Microbiology and Immunology Faculty of Medicine, and Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.
Holterman CE; Kidney Research Center, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Shutinoski B; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Li J; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Fehr TK; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
LaVoie MJ; Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, USA.
Ratan RR; Burke Neurological Institute, Weill Cornell Medical School, White Plains, NY, USA.
Shaw GS; Department of Biochemistry, University of Western Ontario, London, ON, Canada.
Takanashi M; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Hattori N; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Kennedy CR; Kidney Research Center, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Harper ME; Department of Biochemistry, Microbiology and Immunology Faculty of Medicine, and Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.
Holmgren A; Department of Biochemistry, Karolinska Institute, Stockholm, Sweden.
Tomlinson JJ; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada. .; University of Ottawa Brain and Mind Research Institute, Ottawa, ON, Canada. .
Schlossmacher MG; Program in Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada. .; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada. .; University of Ottawa Brain and Mind Research Institute, Ottawa, ON, Canada. .; Division of Neurology, Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Jan 23; Vol. 11 (1), pp. 19. Date of Electronic Publication: 2023 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione*/metabolism
Proteins*/metabolism
Adult ; Mice ; Humans ; Animals ; Glutathione Disulfide/metabolism ; Oxidation-Reduction ; Oxidative Stress ; Ubiquitin-Protein Ligases/genetics ; Antioxidants ; Cysteine/metabolism ; Brain/metabolism ; Sulfhydryl Compounds/chemistry ; Sulfhydryl Compounds/metabolism ; Mammals/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
A Class of Disulfide Compounds Suppresses Ferroptosis by Stabilizing GPX4.
Autorzy:
Liu JP; The Fifth People's Hospital of Shanghai, Molecular and Cell Biology Laboratory, Institutes of Biomedical Sciences and the School of Pharmacy, Fudan University, Shanghai200032, China.
Cen SY; The Fifth People's Hospital of Shanghai, Molecular and Cell Biology Laboratory, Institutes of Biomedical Sciences and the School of Pharmacy, Fudan University, Shanghai200032, China.
Xue Z; The Fifth People's Hospital of Shanghai, Molecular and Cell Biology Laboratory, Institutes of Biomedical Sciences and the School of Pharmacy, Fudan University, Shanghai200032, China.
Wang TX; The Fifth People's Hospital of Shanghai, Molecular and Cell Biology Laboratory, Institutes of Biomedical Sciences and the School of Pharmacy, Fudan University, Shanghai200032, China.
Gao Y; The Fifth People's Hospital of Shanghai, Molecular and Cell Biology Laboratory, Institutes of Biomedical Sciences and the School of Pharmacy, Fudan University, Shanghai200032, China.
Zheng J; Center for Novel Target and Therapeutic Intervention, Institute of Life Sciences, Chongqing Medical University, Chongqing400016, China.
Zhang C; The Fifth People's Hospital of Shanghai, Molecular and Cell Biology Laboratory, Institutes of Biomedical Sciences and the School of Pharmacy, Fudan University, Shanghai200032, China.
Hu J; Center for Novel Target and Therapeutic Intervention, Institute of Life Sciences, Chongqing Medical University, Chongqing400016, China.
Nie S; Center for Novel Target and Therapeutic Intervention, Institute of Life Sciences, Chongqing Medical University, Chongqing400016, China.
Xiong Y; Cullgen Inc., 12671 High Bluff Drive, San Diego, California92130, United States.
Guan KL; Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, California92093, United States.
Yuan HX; The Fifth People's Hospital of Shanghai, Molecular and Cell Biology Laboratory, Institutes of Biomedical Sciences and the School of Pharmacy, Fudan University, Shanghai200032, China.; Center for Novel Target and Therapeutic Intervention, Institute of Life Sciences, Chongqing Medical University, Chongqing400016, China.
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Źródło:
ACS chemical biology [ACS Chem Biol] 2022 Dec 16; Vol. 17 (12), pp. 3389-3406. Date of Electronic Publication: 2022 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Disulfides*/pharmacology
Ferroptosis*/drug effects
Phospholipid Hydroperoxide Glutathione Peroxidase*/drug effects
Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism
Animals ; Mice ; Dithionitrobenzoic Acid ; Glutathione/metabolism ; Lipid Peroxidation/physiology ; Sulfides ; Disulfiram/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Salvianolic acid B inhibits myocardial I/R-induced ROS generation and cell apoptosis by regulating the TRIM8/GPX1 pathway.
Autorzy:
Lu B; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Li J; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Gui M; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yao L; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fan M; Shanghai Leiyunshang Pharmaceutical Co., Ltd., Shanghai, China.
Zhou X; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fu D; Department of Cardiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 1458-1468.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Benzofurans*/pharmacology
Benzofurans*/therapeutic use
Depsides*/pharmacology
Depsides*/therapeutic use
Glutathione Peroxidase*/genetics
Myocardial Reperfusion Injury*/drug therapy
Myocardial Reperfusion Injury*/genetics
Myocardial Reperfusion Injury*/metabolism
Myocardial Reperfusion Injury*/prevention & control
Animals ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cell Line ; Female ; Humans ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Szczegóły
Tytuł:
Glutathione S-Transferases S1, Z1 and A1 Serve as Prognostic Factors in Glioblastoma and Promote Drug Resistance through Antioxidant Pathways.
Autorzy:
Cheng B; Department of Psychiatry, The Affiliated Xuzhou Eastern Hospital of Xuzhou Medical University, Tongshan Road 379, Xuzhou 221000, China.; The Key Lab of Psychiatry, Xuzhou Medical University, Tongshan Road 209, Xuzhou 221000, China.
Wang Y; Department of Geriatric Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Guangzhou Road 264, Nanjing 220029, China.
Ayanlaja AA; Department of Neurology, Johns Hopkins University School of Medicine, 201 N Broadway, Baltimore, MD 21287, USA.
Zhu J; Department of Psychiatry, The Affiliated Xuzhou Eastern Hospital of Xuzhou Medical University, Tongshan Road 379, Xuzhou 221000, China.
Kambey PA; Department of Neurobiology and Cell Biology, Xuzhou Medical University, Tongshan Road 209, Xuzhou 221000, China.
Qiu Z; Department of Psychiatry, The Affiliated Xuzhou Eastern Hospital of Xuzhou Medical University, Tongshan Road 379, Xuzhou 221000, China.
Zhang C; Department of Psychiatry, The Affiliated Xuzhou Eastern Hospital of Xuzhou Medical University, Tongshan Road 379, Xuzhou 221000, China.; The Key Lab of Psychiatry, Xuzhou Medical University, Tongshan Road 209, Xuzhou 221000, China.
Hu W; Department of Psychiatry, The Affiliated Xuzhou Eastern Hospital of Xuzhou Medical University, Tongshan Road 379, Xuzhou 221000, China.
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Źródło:
Cells [Cells] 2022 Oct 14; Vol. 11 (20). Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glioblastoma*/diagnosis
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Glutathione Transferase*/genetics
Glutathione Transferase*/metabolism
Drug Resistance, Neoplasm*
Humans ; Glutathione/metabolism ; Prognosis ; Temozolomide/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biochemical and Structural Characterization of Chi-Class Glutathione Transferases: A Snapshot on the Glutathione Transferase Encoded by sll0067 Gene in the Cyanobacterium Synechocystis sp. Strain PCC 6803.
Autorzy:
Mocchetti E; Université de Lorraine, CNRS, CRM2, F-54000 Nancy, France.
Morette L; Université de Lorraine, INRAE, IAM, F-54000 Nancy, France.
Mulliert G; Université de Lorraine, CNRS, CRM2, F-54000 Nancy, France.
Mathiot S; Université de Lorraine, CNRS, CRM2, F-54000 Nancy, France.
Guillot B; Université de Lorraine, CNRS, CRM2, F-54000 Nancy, France.
Dehez F; Université de Lorraine, CNRS, LPCT, F-54000 Nancy, France.
Chauvat F; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), F-91190 Gif-sur-Yvette, France.
Cassier-Chauvat C; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), F-91190 Gif-sur-Yvette, France.
Brochier-Armanet C; Université de Lyon 1, CNRS, LBBE, F-69622 Villeurbanne, France.
Didierjean C; Université de Lorraine, CNRS, CRM2, F-54000 Nancy, France.
Hecker A; Université de Lorraine, INRAE, IAM, F-54000 Nancy, France.
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Źródło:
Biomolecules [Biomolecules] 2022 Oct 13; Vol. 12 (10). Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glutathione Transferase*/metabolism
Synechocystis*/genetics
Synechocystis*/metabolism
Pyruvaldehyde ; Glutathione/metabolism ; Protein Structure, Secondary
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Myricetin as a Potential Adjuvant in Chemotherapy: Studies on the Inhibition of Human Glutathione Transferase A1-1.
Autorzy:
Alqarni MH; Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Alkharj 11942, Saudi Arabia.
Foudah AI; Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Alkharj 11942, Saudi Arabia.
Muharram MM; Department of Microbiology, College of Science, Al-Azhar University, Nasr City, Cairo 11884, Egypt.
Alam A; Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Alkharj 11942, Saudi Arabia.
Labrou NE; Laboratory of Enzyme Technology, Department of Biotechnology, School of Food, Biotechnology and Development, Agricultural University of Athens, 75 Iera Odos Street, GR-11855 Athens, Greece.
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Źródło:
Biomolecules [Biomolecules] 2022 Sep 24; Vol. 12 (10). Date of Electronic Publication: 2022 Sep 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Flavonoids*/pharmacology
Glutathione Transferase*/antagonists & inhibitors
Glutathione Transferase*/metabolism
Humans ; Dinitrochlorobenzene ; Glutathione/metabolism ; Kinetics ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Computational insights into diverse aspects of glutathione S-transferase gene family in Papaver somniferum.
Autorzy:
Vaish S; Faculty of Biosciences, Institute of Biosciences and Technology, Shri Ramswaroop Memorial University, Lucknow Deva Road, Barabanki, Uttar Pradesh, 225003, India.
Parveen R; Faculty of Biosciences, Institute of Biosciences and Technology, Shri Ramswaroop Memorial University, Lucknow Deva Road, Barabanki, Uttar Pradesh, 225003, India.
Rajneesh; Banaras Hindu University, Varanasi, 221005, India.
Singh N; Faculty of Biosciences, Institute of Biosciences and Technology, Shri Ramswaroop Memorial University, Lucknow Deva Road, Barabanki, Uttar Pradesh, 225003, India.
Gupta D; Faculty of Biosciences, Institute of Biosciences and Technology, Shri Ramswaroop Memorial University, Lucknow Deva Road, Barabanki, Uttar Pradesh, 225003, India.
Basantani MK; Faculty of Biosciences, Institute of Biosciences and Technology, Shri Ramswaroop Memorial University, Lucknow Deva Road, Barabanki, Uttar Pradesh, 225003, India. .
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Źródło:
Journal of plant research [J Plant Res] 2022 Nov; Vol. 135 (6), pp. 823-852. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione Transferase*/genetics
Glutathione Transferase*/chemistry
Glutathione Transferase*/metabolism
Papaver*/genetics
Papaver*/metabolism
Gene Expression Regulation, Plant ; Phylogeny ; Opium ; Plants/genetics ; Glutathione/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Biophysical description of Bromosulfophthalein interaction with the 28-kDa glutathione transferase from Schistosoma japonicum.
Autorzy:
Pooe K; Protein Structure-Function and Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Braamfontein 2050, Johannesburg, South Africa.
Thulo M; Protein Structure-Function and Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Braamfontein 2050, Johannesburg, South Africa.
Makumbe H; Protein Structure-Function and Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Braamfontein 2050, Johannesburg, South Africa.
Akumadu B; Protein Structure-Function and Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Braamfontein 2050, Johannesburg, South Africa.
Otun O; Protein Structure-Function and Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Braamfontein 2050, Johannesburg, South Africa.
Aloke C; Protein Structure-Function and Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Braamfontein 2050, Johannesburg, South Africa.
Achilonu I; Protein Structure-Function and Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Braamfontein 2050, Johannesburg, South Africa. Electronic address: .
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Źródło:
Molecular and biochemical parasitology [Mol Biochem Parasitol] 2022 Nov; Vol. 252, pp. 111524. Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Glutathione Transferase*/antagonists & inhibitors
Schistosoma japonicum*/drug effects
Schistosoma japonicum*/enzymology
Sulfobromophthalein*/pharmacology
Animals ; Binding Sites ; Calorimetry ; Glutathione/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Determination of glutathione in blood via capillary electrophoresis with pH-mediated stacking.
Autorzy:
Ivanov AV; Department of Molecular and Cell Pathophysiology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Popov MA; Department of Cardiac Surgery, M.F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia.
Aleksandrin VV; Department of Molecular and Cell Pathophysiology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Kozhevnikova LM; Department of Molecular and Cell Pathophysiology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Moskovtsev AA; Department of Molecular and Cell Pathophysiology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Kruglova MP; Department of Human Pathology, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.
Vladimirovna SE; Department of Human Pathology, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.
Aleksandrovich SV; Department of Hospital Surgery №1, Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia.
Kubatiev AA; Department of Molecular and Cell Pathophysiology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
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Źródło:
Electrophoresis [Electrophoresis] 2022 Oct; Vol. 43 (18-19), pp. 1859-1870. Date of Electronic Publication: 2022 Jul 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ether*
Glutathione*/analysis
Acetonitriles ; Cetrimonium ; Citrates ; Edetic Acid ; Electrophoresis, Capillary/methods ; Ethylmaleimide ; Glutathione Disulfide/analysis ; Humans ; Hydrogen-Ion Concentration ; Silicon Dioxide ; Sodium Dodecyl Sulfate
Czasopismo naukowe
Szczegóły
Tytuł:
Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation.
Autorzy:
Koirala B K S; Department of Entomology, Pennsylvania State University, University Park, PA 16802, USA.
Moural T; Department of Entomology, Pennsylvania State University, University Park, PA 16802, USA.
Zhu F; Department of Entomology, Pennsylvania State University, University Park, PA 16802, USA.; Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA.
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Źródło:
International journal of biological sciences [Int J Biol Sci] 2022 Sep 11; Vol. 18 (15), pp. 5713-5723. Date of Electronic Publication: 2022 Sep 11 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Xenobiotics*
Glutathione Transferase*/genetics
Glutathione Transferase*/chemistry
Glutathione Transferase*/metabolism
Animals ; Insecta/genetics ; Insecta/metabolism ; Glutathione ; Amino Acids ; Multifunctional Enzymes
Czasopismo naukowe
Szczegóły
Tytuł:
Association Analysis of GSTP1-rs1695 Polymorphism with the Risk of Oral Cancer: A Literature Review, an Updated Meta- Analysis, and a Structural Assessment.
Autorzy:
Baghaei A; Faculty of Medicine, Islamic Azad University of Mashhad, Mashhad, Iran.
Behjati M; Cellular, Molecular and Genetics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Karimian A; Department of Otolaryngology, School of Medicine, Kashan University of Medical Science, Kashan, Iran.
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Źródło:
Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2022 Nov 01; Vol. 23 (11), pp. 3859-3868. Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Review; Meta-Analysis; Journal Article
MeSH Terms:
Glutathione Transferase*
Mouth Neoplasms*/etiology
Mouth Neoplasms*/genetics
Humans ; Polymorphism, Genetic/genetics ; Ethnicity ; Computational Biology ; Glutathione S-Transferase pi/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation.
Autorzy:
Potęga A; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology, Gabriela Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Aug 17; Vol. 27 (16). Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents*/pharmacology
Glutathione*/metabolism
Biotransformation ; Glutathione Transferase/metabolism ; Xenobiotics/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression.
Autorzy:
Zhang L; Department of Neurosurgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Wang X; Department of Neurosurgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Che W; Department of Neurosurgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Yi Y; Department of Neurosurgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Zhou S; Department of Neurosurgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Feng Y; Department of Neurosurgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
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Źródło:
Bioengineered [Bioengineered] 2022 Jun; Vol. 13 (6), pp. 14215-14226.
Typ publikacji:
Journal Article
MeSH Terms:
Cerebral Hemorrhage*/metabolism
Cerebral Hemorrhage*/pathology
Ferroptosis*
Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism
Animals ; Endothelial Cells/metabolism ; Glucose/metabolism ; Glutathione/metabolism ; Methyltransferases/metabolism ; Mice ; Oxygen/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Identification, analysis of deleterious SNPs of the human GSR gene and their effects on the structure and functions of associated proteins and other diseases.
Autorzy:
Vyas B; School of Interdisciplinary Studies, Jamia Hamdard, New Delhi, India.
Bhowmik R; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India.
Akhter M; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India. .
Ahmad FJ; School of Interdisciplinary Studies, Jamia Hamdard, New Delhi, India.; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India.
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Źródło:
Scientific reports [Sci Rep] 2022 Mar 31; Vol. 12 (1), pp. 5474. Date of Electronic Publication: 2022 Mar 31.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione Reductase*/genetics
Polymorphism, Single Nucleotide*
Glutathione ; Glutathione Disulfide ; Humans ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Radiation affects glutathione redox reaction by reduced glutathione peroxidase activity in human fibroblasts.
Autorzy:
Shimura T; Department of Environmental Health; National Institute of Public Health 2-3-6 Minami; Wako, Saitama, 351-0197, Japan.
Nakashiro C; Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo, 204-8588, Japan.
Fujiwara K; Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo, 204-8588, Japan.
Shiga R; Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo, 204-8588, Japan.
Sasatani M; Department of Experimental Oncology; Research Center for Radiation Genome Medicine; Research Institute for Radiation Biology and Medicine (RIRBM); Hiroshima University, Hiroshima, 734-8551, Japan.
Kamiya K; Department of Experimental Oncology; Research Center for Radiation Genome Medicine; Research Institute for Radiation Biology and Medicine (RIRBM); Hiroshima University, Hiroshima, 734-8551, Japan.
Ushiyama A; Department of Environmental Health; National Institute of Public Health 2-3-6 Minami; Wako, Saitama, 351-0197, Japan.
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Źródło:
Journal of radiation research [J Radiat Res] 2022 Mar 17; Vol. 63 (2), pp. 183-191.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/metabolism
Glutathione*/metabolism
Fibroblasts/*radiation effects
Fibroblasts/metabolism ; Glutathione Peroxidase/metabolism ; Humans ; Oxidation-Reduction ; Oxidative Stress ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Electrochemical Zero-Mode Waveguide Potential-Dependent Fluorescence of Glutathione Reductase at Single-Molecule Occupancy.
Autorzy:
Baek S; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Han D; Department of Chemistry, The Catholic University of Korea, Bucheon, Gyeonggi-do 14662, South Korea.
Kwon SR; Department of Chemistry and Research Institute of Natural Science, Gyeongsang National University, Jinju 52828, South Korea.
Sundaresan V; Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Bohn PW; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.; Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, United States.
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Źródło:
Analytical chemistry [Anal Chem] 2022 Mar 08; Vol. 94 (9), pp. 3970-3977. Date of Electronic Publication: 2022 Feb 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Glutathione*
Glutathione Reductase*/chemistry
Nanotechnology*
Single Molecule Imaging*/methods
Diffusion ; Fluorescence ; Glutathione Disulfide ; Oxidation-Reduction
Czasopismo naukowe
Szczegóły
Tytuł:
Global Quantification of Glutathione S-Transferases in Human Serum Using LC-MS/MS Coupled with Affinity Enrichment.
Autorzy:
Zhang Y; College of Life Sciences & Sino-Danish College, University of Chinese Academy of Sciences, Beijing 100049, China.; BGI-Shenzhen, Shenzhen 518083, China.; Beijing Institute of Genomics & China National Center for Bioinformation, Chinese Academy of Sciences, Beijing 100101, China.
Huang D; Department of Liver Diseases, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518100, China.
Lv N; Department of Clinical Laboratory, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, National Clinical Research Center for Infectious Diseases, Shenzhen 518114, China.
Zhu G; BGI-Shenzhen, Shenzhen 518083, China.
Peng J; Department of Liver Diseases, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518100, China.
Chou T; BGI-Shenzhen, Shenzhen 518083, China.
Zhu Z; Department of Liver Diseases, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518100, China.
Wang J; BGI-Shenzhen, Shenzhen 518083, China.
Chen Y; Department of Liver Diseases, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518100, China.
Fang X; College of Life Sciences & Sino-Danish College, University of Chinese Academy of Sciences, Beijing 100049, China.; Beijing Institute of Genomics & China National Center for Bioinformation, Chinese Academy of Sciences, Beijing 100101, China.
Qu J; Department of Clinical Laboratory, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, National Clinical Research Center for Infectious Diseases, Shenzhen 518114, China.
Chen J; Department of Liver Diseases, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518100, China.
Liu S; BGI-Shenzhen, Shenzhen 518083, China.
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Źródło:
Journal of proteome research [J Proteome Res] 2022 May 06; Vol. 21 (5), pp. 1311-1320. Date of Electronic Publication: 2022 Mar 30.
Typ publikacji:
Journal Article
MeSH Terms:
Glutathione Transferase*/analysis
Tandem Mass Spectrometry*
Chromatography, Liquid ; Glutathione ; Humans ; Liver ; Peptides ; Proteomics/methods
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 200689

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