Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""Glycogen Synthase Kinase 3 beta"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 1957
Tytuł:
Transcriptional Regulation of the Human 5-HT1A Receptor Gene by Lithium: Role of Deaf1 and GSK3β.
Autorzy:
Harkin EF; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, 451 Smyth Road, Ottawa, ON K1H-8M5, Canada.
Nasrallah G; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, 451 Smyth Road, Ottawa, ON K1H-8M5, Canada.
Le François B; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, 451 Smyth Road, Ottawa, ON K1H-8M5, Canada.
Albert PR; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, 451 Smyth Road, Ottawa, ON K1H-8M5, Canada.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 26; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Glycogen Synthase Kinase 3 beta*/genetics
Lithium*/pharmacology
Receptor, Serotonin, 5-HT1A*/genetics
Serotonin*/pharmacology
Humans ; Antidepressive Agents ; HEK293 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GSK3β Inhibition Ameliorates Atherosclerotic Calcification.
Autorzy:
Cai X; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Zhao Y; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Yang Y; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Wu X; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Zhang L; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Ma JA; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Ji J; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Boström KI; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.; The Molecular Biology Institute at UCLA, Los Angeles, CA 90095-1570, USA.
Yao Y; Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1679, USA.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 19; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*/drug therapy
Atherosclerosis*/genetics
Atherosclerosis*/metabolism
Glycogen Synthase Kinase 3 beta*/antagonists & inhibitors
Glycogen Synthase Kinase 3 beta*/genetics
Vascular Calcification*/drug therapy
Vascular Calcification*/chemically induced
Animals ; Mice ; beta Catenin/genetics ; beta Catenin/metabolism ; Calcification, Physiologic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SFRP2 suppresses trophoblast cell migration by inhibiting the Wnt/β‑catenin pathway.
Autorzy:
Lan R; Department of Obstetrics, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570311, P.R. China.
Yu Y; School of Clinical Medicine, Hainan Medical University, Haikou, Hainan 571199, P.R. China.
Song J; Department of Obstetrics, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570311, P.R. China.
Xue M; School of Clinical Medicine, Hainan Medical University, Haikou, Hainan 571199, P.R. China.
Gong H; Department of Obstetrics, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570311, P.R. China.
Źródło:
Molecular medicine reports [Mol Med Rep] 2024 Apr; Vol. 29 (4). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
beta Catenin*/genetics
beta Catenin*/metabolism
Humans ; Female ; Pregnancy ; Cell Line, Tumor ; Glycogen Synthase Kinase 3 beta/genetics ; Glycogen Synthase Kinase 3 beta/metabolism ; Secreted Frizzled-Related Proteins ; Placenta/metabolism ; Wnt Proteins/metabolism ; Trophoblasts/metabolism ; Cell Proliferation ; Cell Movement/genetics ; Membrane Proteins/genetics ; Membrane Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microdose lithium improves behavioral deficits and modulates molecular mechanisms of memory formation in female SAMP-8, a mouse model of accelerated aging.
Autorzy:
Pereira AAR; Department of Pharmacology, Institute of Biomedical Sciences, Graduate Course on Pharmacology, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil.; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Pinto AM; Graduate Course on Gerontology, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Malerba HN; Department of Pharmacology, Institute of Biomedical Sciences, Graduate Course on Pharmacology, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil.; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Toricelli M; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Buck HS; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.; Department of Physiology, University of Mogi das Cruzes, Mogi das Cruzes, Sao Paulo, Brazil.
Viel TA; Department of Pharmacology, Institute of Biomedical Sciences, Graduate Course on Pharmacology, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil.; Laboratory of Neuropharmacology of Aging, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.; Graduate Course on Gerontology, School of Arts, Sciences and Humanities, Universidade de São Paulo, Sao Paulo, Sao Paulo, Brazil.
Źródło:
PloS one [PLoS One] 2024 Apr 04; Vol. 19 (4), pp. e0299534. Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Lithium*/pharmacology
Lithium*/therapeutic use
Alzheimer Disease*/pathology
Phenylmercury Compounds*
Mice ; Female ; Animals ; Plaque, Amyloid/pathology ; Glycogen Synthase Kinase 3 beta ; Aging/metabolism ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
17 variants interaction of Wnt/β-catenin pathway associated with development of osteonecrosis of femoral head in Chinese Han population.
Autorzy:
Shi C; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.
Li X; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.
Sun Y; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.
Du Z; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.
Zhang G; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.; Gene Testing Centre of Changchun Tumor Hospital, Changchun City, 130012, Jilin Province, China.
Che Z; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.
Li Q; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.
Song S; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.
Guo J; Gene Testing Centre of Changchun Tumor Hospital, Changchun City, 130012, Jilin Province, China.
Sun H; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China.
Song Y; Medical Centre of Orthopedics, The Second Hospital of Jilin University, Ziqiang Street No.218, Nanguan District, Changchun City, 130041, Jilin Province, China. .
Źródło:
Scientific reports [Sci Rep] 2024 Mar 27; Vol. 14 (1), pp. 7301. Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:
Journal Article
MeSH Terms:
Femur Head Necrosis*/genetics
Osteonecrosis*/genetics
Humans ; Femur Head ; beta Catenin/genetics ; Glycogen Synthase Kinase 3 beta/genetics ; Polymorphism, Single Nucleotide ; Lipids ; China ; Case-Control Studies ; Genetic Predisposition to Disease
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Autorzy:
Fei X; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China.
Zhu C; Department of Hepatobiliary Surgery, Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.
Liu P; Department of Hepatobiliary Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.
Liu S; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China.; Department of Hepatobiliary Surgery, Baiyun Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.
Ren L; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China.
Lu R; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China.
Hou J; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China.
Gao Y; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China.
Wang X; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China. .; Department of Hepatobiliary Surgery, Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. .
Pan Y; School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China. .; Department of Hepatobiliary Surgery, Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. .
Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Mar 25; Vol. 43 (1), pp. 91. Date of Electronic Publication: 2024 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Ubiquitin-Protein Ligases*/genetics
Ubiquitin-Protein Ligases*/metabolism
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Glycogen Synthase Kinase 3 beta/metabolism ; Mice, Nude ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Therapeutic potential of salidroside in preserving rat cochlea organ of corti from gentamicin-induced injury through modulation of NRF2 signaling and GSK3β/NF-κB pathway.
Autorzy:
Zhang Y; Department of Otolaryngology-Head and Neck Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Yu S; Department of Otolaryngology-Head and Neck Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Guo X; Department of Otolaryngology-Head and Neck Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Wang L; Department of Regenerative Medicine, College of Pharmacy, Jilin University, Changchun, Jilin, China.
Yu L; Department of Pharmacy, the Second Hospital of Jilin University, Changchun, Jilin, China.
Wang P; Department of Otolaryngology-Head and Neck Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Źródło:
PloS one [PLoS One] 2024 Mar 14; Vol. 19 (3), pp. e0298529. Date of Electronic Publication: 2024 Mar 14 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Gentamicins*/toxicity
Gentamicins*/metabolism
Ototoxicity*
Glucosides*
Rats ; Animals ; NF-kappa B/metabolism ; Antioxidants/pharmacology ; Antioxidants/metabolism ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Glycogen Synthase Kinase 3 beta/metabolism ; Glycogen Synthase Kinase 3/metabolism ; Hair Cells, Auditory ; Cochlea/metabolism ; Phenols/pharmacology ; Phenols/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oligodendrocyte-derived exosomes-containing SIRT2 ameliorates depressive-like behaviors and restores hippocampal neurogenesis and synaptic plasticity via the AKT/GSK-3β pathway in depressed mice.
Autorzy:
Zhang H; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Xie XH; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Xu SX; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Wang C; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Sun S; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Song X; Clinical College of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Li R; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Li N; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Feng Y; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Duan H; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Li D; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu Z; Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14661.
Typ publikacji:
Journal Article
MeSH Terms:
Exosomes*
Animals ; Mice ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Glycogen Synthase Kinase 3 beta ; Hippocampus ; Neurogenesis ; Neuronal Plasticity ; Oligodendroglia ; Proto-Oncogene Proteins c-akt ; Sirtuin 2
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Marked alteration of phosphoinositide signaling-associated molecules in postmortem prefrontal cortex with bipolar disorder.
Autorzy:
Hino M; Department of Disaster Psychiatry, International Research Institute of Disaster Science, Tohoku University, Sendai, Japan.; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, Fukushima, Japan.
Kunii Y; Department of Disaster Psychiatry, International Research Institute of Disaster Science, Tohoku University, Sendai, Japan.; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, Fukushima, Japan.
Shishido R; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, Fukushima, Japan.
Nagaoka A; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, Fukushima, Japan.
Matsumoto J; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, Fukushima, Japan.
Akatsu H; Department of Community-Based Medical Education/Department of Community-Based Medicine, Nagoya City University Graduate School of Medical Science, Nagoya, Aichi, Japan.; Choju Medical Institute, Fukushimura Hospital, Toyohashi, Aichi, Japan.
Hashizume Y; Choju Medical Institute, Fukushimura Hospital, Toyohashi, Aichi, Japan.
Hayashi H; Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan.
Kakita A; Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan.
Tomita H; Department of Psychiatry, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.
Yabe H; Department of Disaster Psychiatry, International Research Institute of Disaster Science, Tohoku University, Sendai, Japan.
Źródło:
Neuropsychopharmacology reports [Neuropsychopharmacol Rep] 2024 Mar; Vol. 44 (1), pp. 121-128. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Bipolar Disorder*
Humans ; Lithium ; Glycogen Synthase Kinase 3 beta ; Signal Transduction/physiology ; Prefrontal Cortex
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway.
Autorzy:
Song M; Department of Respiratory and Critical Care Medicine, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China.
Liu X; Department of Respiratory and Critical Care Medicine, The Xuzhou Municipal Hospital Affiliated to Xuzhou Medical University, Xuzhou, China.
Shen W; Department of Respiratory and Critical Care Medicine, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Wang Z; Department of Respiratory and Critical Care Medicine, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China.
Wu J; Department of Respiratory and Critical Care Medicine, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China.
Jiang J; Department of Respiratory and Critical Care Medicine, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China.
Liu Y; Department of Respiratory and Critical Care Medicine, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China.
Xu T; Department of Respiratory and Critical Care Medicine, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China.
Bian T; Department of Respiratory and Critical Care Medicine, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Zhang M; Jiangsu Province Engineering Research Center of Antibody Drug, NHC Key Laboratory of Antibody Technique, Department of Immunology, Nanjing Medical University, Nanjing, China. .
Sun W; Department of Respiratory and Critical Care Medicine, Xishan People's Hospital of Wuxi City, Wuxi, China. .
Huang M; Department of Respiratory and Critical Care Medicine, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China. .
Ji N; Department of Respiratory and Critical Care Medicine, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China. .
Źródło:
Scientific reports [Sci Rep] 2024 Feb 29; Vol. 14 (1), pp. 5038. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*
COVID-19*/metabolism
Aged ; Humans ; Glycogen Synthase Kinase 3 beta/metabolism ; Interferon-gamma/metabolism ; Post-Acute COVID-19 Syndrome ; Programmed Cell Death 1 Receptor/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Beyond Amyloid: A Machine Learning-Driven Approach Reveals Properties of Potent GSK-3β Inhibitors Targeting Neurofibrillary Tangles.
Autorzy:
Nwadiugwu M; Tulane Center for Biomedical Informatics and Genomics, Deming Department of Medicine, Tulane University School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Onwuekwe I; Neurology Unit, Department of Medicine, University of Nigeria Teaching Hospital, Ituku-Ozalla 400001, Enugu, Nigeria.; Department of Medicine, College of Medicine, University of Nigeria, Enugu Campus, Nsukka 400001, Enugu, Nigeria.
Ezeanolue E; Center for Translation and Implementation Research (CTAIR), University of Nigeria, Nsukka 410001, Enugu, Nigeria.; Healthy Sunrise Foundation, Las Vegas, NV 89107, USA.
Deng H; Tulane Center for Biomedical Informatics and Genomics, Deming Department of Medicine, Tulane University School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 24; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Neurofibrillary Tangles*/metabolism
Alzheimer Disease*/pathology
Humans ; Glycogen Synthase Kinase 3 beta ; tau Proteins/metabolism ; Neurons/metabolism ; Amyloid ; Amyloidogenic Proteins/therapeutic use ; Phosphorylation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
DPPA2/4 Promote the Pluripotency and Proliferation of Bovine Extended Pluripotent Stem Cells by Upregulating the PI3K/AKT/GSK3β/β-Catenin Signaling Pathway.
Autorzy:
Fang S; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010070, China.
Wang J; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010070, China.
Liu G; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010070, China.
Qu B; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010070, China.
Chunyu J; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010070, China.
Xu W; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010070, China.
Xiang J; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010070, China.
Li X; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010070, China.
Źródło:
Cells [Cells] 2024 Feb 23; Vol. 13 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
beta Catenin*/metabolism
Pluripotent Stem Cells*/metabolism
Transcription Factors*/metabolism
Nuclear Proteins*/metabolism
Animals ; Cattle ; Cell Proliferation ; Glycogen Synthase Kinase 3 beta/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stimulating VAPB-PTPIP51 ER-mitochondria tethering corrects FTD/ALS mutant TDP43 linked Ca and synaptic defects.
Autorzy:
Markovinovic A; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK. .
Martín-Guerrero SM; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Mórotz GM; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Salam S; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Gomez-Suaga P; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Paillusson S; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Greig J; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Lee Y; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Mitchell JC; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Noble W; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK.
Miller CCJ; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9RX, London, UK. .
Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Feb 23; Vol. 12 (1), pp. 32. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/pathology
Frontotemporal Dementia*/genetics
Frontotemporal Dementia*/metabolism
Neurodegenerative Diseases*/metabolism
Vesicular Transport Proteins*/genetics
Humans ; Calcium/metabolism ; Endoplasmic Reticulum/metabolism ; Glycogen Synthase Kinase 3 beta/metabolism ; Mitochondria/metabolism ; Protein Tyrosine Phosphatases/metabolism ; Synapses/pathology ; TDP-43 Proteinopathies/metabolism
SCR Disease Name:
Frontotemporal Dementia With Motor Neuron Disease
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chlorogenic Acid Attenuates Isoproterenol Hydrochloride-Induced Cardiac Hypertrophy in AC16 Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Autorzy:
He K; Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Wang X; Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Li T; College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Li Y; Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Ma L; Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 07; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Chlorogenic Acid*/pharmacology
Humans ; Isoproterenol/toxicity ; Glycogen Synthase Kinase 3 beta/metabolism ; Cardiomegaly/chemically induced ; Cardiomegaly/drug therapy ; beta Catenin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Presenilin-2 knock-In mice show severe depressive behavior via DVL3 downregulation.
Autorzy:
Yoo SS; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.
Lee DW; Ministry of Food and Drug Safety (MFDS), Cheongju, South Korea.; Korea Health Industry Development Institute, Cheongju, South Korea.
Ham HJ; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.
Yeo IJ; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.
Chang JY; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.
Yun J; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.
Son DJ; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.
Han SB; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.
Hong JT; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.
Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14370. Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease*/metabolism
Amyloid beta-Peptides*/metabolism
Animals ; Mice ; Dishevelled Proteins/metabolism ; Down-Regulation ; Glycogen Synthase Kinase 3 beta ; Hydrocortisone ; Mice, Transgenic ; Presenilin-1/genetics ; Presenilin-2/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Glycogen Synthase Kinase 3β: A True Foe in Pancreatic Cancer.
Autorzy:
Elmadbouh OHM; Department of Medicine, Division of Gastroenterology and Hepatology, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Pandol SJ; Department of Medicine, Division of Gastroenterology and Hepatology, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Edderkaoui M; Department of Medicine, Division of Gastroenterology and Hepatology, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 16; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Glycogen Synthase Kinase 3 beta*/genetics
Glycogen Synthase Kinase 3 beta*/metabolism
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Humans ; Apoptosis/physiology ; Signal Transduction ; Pancreatic Neoplasms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neuroprotection and Mechanism of Gas-miR36-5p from Gastrodia elata in an Alzheimer's Disease Model by Regulating Glycogen Synthase Kinase-3β.
Autorzy:
Lu Z; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Fu J; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Wu G; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Yang Z; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Wu X; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Wang D; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
You Z; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Nie Z; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Sheng Q; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 09; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Animal Diseases*
Gastrodia*/genetics
MicroRNAs*/metabolism
MicroRNAs*/pharmacology
Neurodegenerative Diseases*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Animals ; Mice ; Glycogen Synthase Kinase 3 beta/drug effects ; Glycogen Synthase Kinase 3 beta/genetics ; Glycogen Synthase Kinase 3 beta/metabolism ; Neuroprotection ; Phosphorylation ; tau Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Autorzy:
Cui L; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, Guangdong, China. .
Lu Y; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, Guangdong, China.
Zheng J; Department of Dentistry, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Guo B; Department of Dentistry, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Zhao X; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, Guangdong, China. .
Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Dec 07; Vol. 42 (1), pp. 335. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Cisplatin*/pharmacology
Head and Neck Neoplasms*/drug therapy
Head and Neck Neoplasms*/genetics
Animals ; Humans ; Squamous Cell Carcinoma of Head and Neck/drug therapy ; Squamous Cell Carcinoma of Head and Neck/genetics ; Glycogen Synthase Kinase 3 beta/genetics ; Glycogen Synthase Kinase 3 beta/metabolism ; beta Catenin/genetics ; beta Catenin/metabolism ; Integrin beta1/metabolism ; Phosphorylation ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Actinin/genetics ; Actinin/metabolism ; Cell Line, Tumor ; Carcinogenesis/genetics ; Cell Transformation, Neoplastic ; Cell Proliferation ; Myosin Heavy Chains/genetics ; Myosin Heavy Chains/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Rg1 alleviates oxidative stress and spermatogonium apoptosis in D-gal-induced testicular toxicity by activating Akt.
Autorzy:
Wang Z; Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, People's Republic of China.
Du K; Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, People's Republic of China.
Hou J; Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, People's Republic of China.
Xiao H; Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, People's Republic of China.
Hu L; Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, People's Republic of China.
Chen X; Department of Anatomy and Histology and Embryology, Basic Medical College, Chengdu University of Traditional Chinese Medicine, Sichuan, People's Republic of China.
Wang L; Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, People's Republic of China.
Wang Y; Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, People's Republic of China.
Źródło:
Redox report : communications in free radical research [Redox Rep] 2023 Dec; Vol. 28 (1), pp. 2206197.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Testis*/metabolism
Animals ; Male ; Mice ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Apoptosis ; Glycogen Synthase Kinase 3 beta/metabolism ; Glycogen Synthase Kinase 3 beta/pharmacology ; Mice, Inbred C57BL ; Oxidative Stress ; Spermatogonia/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GSK3β Inhibition by Phosphorylation at Ser Controls Neuroinflammation.
Autorzy:
Calvo B; Research Institute for Neurological Disabilities (IDINE), Albacete Medical School, University of Castilla-La Mancha (UCLM), 02008 Albacete, Spain.
Fernandez M; Research Institute for Neurological Disabilities (IDINE), Albacete Medical School, University of Castilla-La Mancha (UCLM), 02008 Albacete, Spain.
Rincon M; Department of Immunology and Microbiology, University of Colorado Denver, Aurora, CO 80045, USA.
Tranque P; Research Institute for Neurological Disabilities (IDINE), Albacete Medical School, University of Castilla-La Mancha (UCLM), 02008 Albacete, Spain.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 25; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 25.
Typ publikacji:
Journal Article
MeSH Terms:
Glycogen Synthase Kinase 3 beta*/chemistry
Neuroinflammatory Diseases*
Animals ; Mice ; Lipopolysaccharides ; Mice, Inbred C57BL ; Phosphorylation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 1957

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies