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Wyszukujesz frazę ""Glycosaminoglycans"" wg kryterium: Temat


Tytuł :
Chondroitin Sulfate N -acetylgalactosaminyltransferase-2 Impacts Foam Cell Formation and Atherosclerosis by Altering Macrophage Glycosaminoglycan Chain.
Autorzy :
Adhikara IM; Laboratory of Clinical Pharmaceutical Science (I.M.A., K.Y., D.S.M., Y.S., K.I., G.R.T.R., N.E.), Kobe Pharmaceutical University, Japan.; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan (I.M.A., D.S.M., Y.S., G.R.T.R., K.-i.H., N.E.).
Yagi K; Laboratory of Clinical Pharmaceutical Science (I.M.A., K.Y., D.S.M., Y.S., K.I., G.R.T.R., N.E.), Kobe Pharmaceutical University, Japan.
Mayasari DS; Laboratory of Clinical Pharmaceutical Science (I.M.A., K.Y., D.S.M., Y.S., K.I., G.R.T.R., N.E.), Kobe Pharmaceutical University, Japan.; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan (I.M.A., D.S.M., Y.S., G.R.T.R., K.-i.H., N.E.).
Suzuki Y; Laboratory of Clinical Pharmaceutical Science (I.M.A., K.Y., D.S.M., Y.S., K.I., G.R.T.R., N.E.), Kobe Pharmaceutical University, Japan.; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan (I.M.A., D.S.M., Y.S., G.R.T.R., K.-i.H., N.E.).
Ikeda K; Laboratory of Clinical Pharmaceutical Science (I.M.A., K.Y., D.S.M., Y.S., K.I., G.R.T.R., N.E.), Kobe Pharmaceutical University, Japan.
Ryanto GRT; Laboratory of Clinical Pharmaceutical Science (I.M.A., K.Y., D.S.M., Y.S., K.I., G.R.T.R., N.E.), Kobe Pharmaceutical University, Japan.; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan (I.M.A., D.S.M., Y.S., G.R.T.R., K.-i.H., N.E.).
Sasaki N; Laboratory of Medical Pharmaceutics (N.S., Y.R.), Kobe Pharmaceutical University, Japan.
Rikitake Y; Laboratory of Medical Pharmaceutics (N.S., Y.R.), Kobe Pharmaceutical University, Japan.
Nadanaka S; Laboratory of Biochemistry (S.N., H.K.), Kobe Pharmaceutical University, Japan.
Kitagawa H; Laboratory of Biochemistry (S.N., H.K.), Kobe Pharmaceutical University, Japan.
Miyata O; Laboratory of Medicinal Chemistry (O.M.), Kobe Pharmaceutical University, Japan.
Igarashi M; Department of Neurochemistry and Molecular Cell Biology, School of Medicine and Graduate School of Medical/Dental Sciences, Niigata University, Japan (M.I.).
Hirata KI; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan (I.M.A., D.S.M., Y.S., G.R.T.R., K.-i.H., N.E.).
Emoto N; Laboratory of Clinical Pharmaceutical Science (I.M.A., K.Y., D.S.M., Y.S., K.I., G.R.T.R., N.E.), Kobe Pharmaceutical University, Japan.; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan (I.M.A., D.S.M., Y.S., G.R.T.R., K.-i.H., N.E.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Mar; Vol. 41 (3), pp. 1076-1091. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Atherosclerosis/*metabolism
Foam Cells/*metabolism
Glycosaminoglycans/*metabolism
N-Acetylgalactosaminyltransferases/*metabolism
Animals ; Atherosclerosis/etiology ; Atherosclerosis/pathology ; Disease Models, Animal ; Female ; Foam Cells/pathology ; Glycosaminoglycans/chemistry ; Lipoproteins, LDL/metabolism ; Macrophages, Peritoneal/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; N-Acetylgalactosaminyltransferases/deficiency ; N-Acetylgalactosaminyltransferases/genetics ; Plaque, Atherosclerotic/etiology ; Plaque, Atherosclerotic/metabolism ; Plaque, Atherosclerotic/pathology ; RAW 264.7 Cells ; Up-Regulation
Czasopismo naukowe
Tytuł :
Nano-Scale Stiffness and Collagen Fibril Deterioration: Probing the Cornea Following Enzymatic Degradation Using Peakforce-QNM AFM.
Autorzy :
Kazaili A; Department of Mechanical, Materials and Aerospace Engineering, School of Engineering, University of Liverpool, Liverpool L69 3GH, UK.; Department of Biomedical Engineering, College of Engineering, University of Babylon, Babylon, Hillah 51002, Iraq.
Abdul-Amir Al-Hindy H; College of Pharmacy, University of Babylon, Babylon, Hillah 51002, Iraq.
Madine J; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7BE, UK.
Akhtar R; Department of Mechanical, Materials and Aerospace Engineering, School of Engineering, University of Liverpool, Liverpool L69 3GH, UK.
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Źródło :
Sensors (Basel, Switzerland) [Sensors (Basel)] 2021 Feb 26; Vol. 21 (5). Date of Electronic Publication: 2021 Feb 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cornea*
Glycosaminoglycans*
Keratoconus*
Animals ; Collagen ; Microscopy, Atomic Force ; Swine
Czasopismo naukowe
Tytuł :
Assembling custom side chains on proteoglycans to interrogate their function in living cells.
Autorzy :
Wang W; National Glycoengineering Research Center and Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao, China.
Han N; National Glycoengineering Research Center and Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao, China.; Shandong Police College, Jinan, China.
Xu Y; National Glycoengineering Research Center and Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao, China.
Zhao Y; Department of Pharmacology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Shi L; National Glycoengineering Research Center and Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao, China.
Filmus J; Sunnybrook Health Science Centre, University of Toronto, Toronto, Ontario, Canada.
Li F; National Glycoengineering Research Center and Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 20; Vol. 11 (1), pp. 5915. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glycosaminoglycans*/chemistry
Glycosaminoglycans*/metabolism
Proteoglycans*/chemistry
Proteoglycans*/metabolism
Glypicans/*metabolism
Animals ; Carbohydrate Metabolism ; Cell Line ; Glycomics/methods ; HEK293 Cells ; Humans ; Mice ; Signal Transduction
Czasopismo naukowe
Tytuł :
Synthesis of structurally defined chondroitin sulfate: Paving the way to the structure-activity relationship studies.
Autorzy :
Ji Y; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China.
Zhang S; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China.
Qiao M; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China.
Jiao R; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China.
Li J; CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Song P; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China.
Zhang X; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China. Electronic address: .
Huang H; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2020 Nov 15; Vol. 248, pp. 116796. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Models, Chemical*
Chondroitin Sulfates/*chemical synthesis
Glycoconjugates/*chemical synthesis
Glycosaminoglycans/*chemical synthesis
Animals ; Anti-Inflammatory Agents/chemical synthesis ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Carbohydrate Sequence ; Chondroitin Sulfates/chemistry ; Chondroitin Sulfates/pharmacology ; Glycoconjugates/chemistry ; Glycoconjugates/pharmacology ; Glycosaminoglycans/chemistry ; Glycosaminoglycans/pharmacology ; Humans ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Coupling Liquid Chromatography and Tandem Mass Spectrometry to Electrophoresis for In-Depth Analysis of Glycosaminoglycan Drugs: Heparin and the Multicomponent Sulodexide.
Autorzy :
Sheng A; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao 266237, China.
Chen Q; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao 266237, China.
Yu M; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao 266237, China.
Xiao R; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao 266237, China.
Zhang T; College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.; Division of Chemistry and Analytical Science, National Institute of Metrology, Beijing 100029, China.
Wang Z; Department of Virology, School of Public Health, Shandong University, Jinan 250012, China.
Linhardt RJ; Department of Chemistry and Chemical Biology, Department of Chemical and Biological Engineering, Department of Biology, and Department of Biomedical Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, United States.
Sun X; Collaborative Innovation Center for Green Chemical Manufacturing and Accurate Detection, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.
Jin L; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao 266237, China.
Chi L; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao 266237, China.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Jan 26; Vol. 93 (3), pp. 1433-1442. Date of Electronic Publication: 2020 Dec 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glycosaminoglycans/*analysis
Heparin/*analysis
Administration, Oral ; Chromatography, Liquid ; Electrophoresis ; Glycosaminoglycans/administration & dosage ; Heparin/administration & dosage ; Humans ; Injections, Intravenous ; Injections, Subcutaneous ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Effects of Glycosaminoglycan from Urechis unicinctus on ADP-Induced Platelet Calcium and Membrane Glycoprotein Expressions in Rats.
Autorzy :
Cui Q; Tianjin Key Laboratory of Marine Resource and Chemistry, Tianjin Marine Environmental Protection and Restoration Technology Engineering Center, College of Marine and Environment, Tianjin University of Science and Technology, Tianjin, China, .
Zhao Z; Tianjin Key Laboratory of Marine Resource and Chemistry, Tianjin Marine Environmental Protection and Restoration Technology Engineering Center, College of Marine and Environment, Tianjin University of Science and Technology, Tianjin, China.
Gao T; Tianjin Key Laboratory of Marine Resource and Chemistry, Tianjin Marine Environmental Protection and Restoration Technology Engineering Center, College of Marine and Environment, Tianjin University of Science and Technology, Tianjin, China.
Yuan C; Tianjin Key Laboratory of Marine Resource and Chemistry, Tianjin Marine Environmental Protection and Restoration Technology Engineering Center, College of Marine and Environment, Tianjin University of Science and Technology, Tianjin, China.
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Źródło :
Acta haematologica [Acta Haematol] 2021; Vol. 144 (1), pp. 44-47. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine Diphosphate/*pharmacology
Biological Products/*pharmacology
Blood Platelets/*drug effects
Blood Platelets/*metabolism
Calcium/*metabolism
Gene Expression Regulation/*drug effects
Glycosaminoglycans/*pharmacology
Platelet Membrane Glycoproteins/*genetics
Polychaeta/*chemistry
Animals ; Biological Products/chemistry ; Calcium Signaling ; Flow Cytometry ; Glycosaminoglycans/chemistry ; Ions/metabolism ; Platelet Membrane Glycoproteins/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Physicochemical characterization and self-assembly of human amniotic membrane and umbilical cord collagen: A comparative study.
Autorzy :
Gunasekaran D; Biological Materials Laboratory, CSIR- Central Leather research Institute (CLRI), Chennai, India; Department of Leather Technology, A C Tech (Housed at CSIR-CLRI), Anna University, Chennai, India.
Thada R; Biological Materials Laboratory, CSIR- Central Leather research Institute (CLRI), Chennai, India; Department of Leather Technology, A C Tech (Housed at CSIR-CLRI), Anna University, Chennai, India.
Jeyakumar GFS; Biological Materials Laboratory, CSIR- Central Leather research Institute (CLRI), Chennai, India.
Manimegalai NP; Biological Materials Laboratory, CSIR- Central Leather research Institute (CLRI), Chennai, India.
Shanmugam G; Organic and Bioorganic Chemistry Laboratory, CSIR-CLRI, Chennai, India.
Sivagnanam UT; Biological Materials Laboratory, CSIR- Central Leather research Institute (CLRI), Chennai, India; Department of Leather Technology, A C Tech (Housed at CSIR-CLRI), Anna University, Chennai, India. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 15; Vol. 165 (Pt B), pp. 2920-2933. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation/*drug effects
Collagen/*chemistry
Glycosaminoglycans/*chemistry
Mesenchymal Stem Cells/*drug effects
Amnion/chemistry ; Chromatography, Liquid ; Collagen/classification ; Collagen/isolation & purification ; Collagen/pharmacology ; Fibroblasts/drug effects ; Glycosaminoglycans/isolation & purification ; Humans ; Pepsin A/pharmacology ; Tandem Mass Spectrometry ; Umbilical Cord/chemistry
Czasopismo naukowe
Tytuł :
Artemisinin inhibits glycosaminoglycan chain synthesizing gene expression but not proliferation of human vascular smooth muscle cells.
Autorzy :
Zhou Y; School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, 4102, Australia. Electronic address: .
Kumarapperuma H; School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, 4102, Australia. Electronic address: .
Sichone S; School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, 4102, Australia. Electronic address: .
Chia ZJ; School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, 4102, Australia. Electronic address: .
Little PJ; School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, 4102, Australia; Department of Pharmacy, Xinhua College of Sun Yat-sen University, Tianhe District, Guangzhou, 510520, China. Electronic address: .
Xu S; Department of Endocrinology and Metabolism, First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology, Hefei, 230037, China. Electronic address: .
Kamato D; School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Woolloongabba, Queensland, 4102, Australia; Department of Pharmacy, Xinhua College of Sun Yat-sen University, Tianhe District, Guangzhou, 510520, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Nov 05; Vol. 532 (2), pp. 239-243. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Artemisinins/*pharmacology
Glycosaminoglycans/*genetics
Muscle, Smooth, Vascular/*cytology
Cell Line ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Gene Expression Regulation/drug effects ; Glucuronosyltransferase/genetics ; Glycosaminoglycans/biosynthesis ; Humans ; Multifunctional Enzymes/genetics ; Muscle, Smooth, Vascular/drug effects ; N-Acetylgalactosaminyltransferases/genetics ; Phosphorylation/drug effects ; Smad2 Protein/metabolism ; Sulfotransferases/genetics ; Transforming Growth Factor beta/pharmacology
Czasopismo naukowe
Tytuł :
Molecular Alterations Prompted by SARS-CoV-2 Infection: Induction of Hyaluronan, Glycosaminoglycan and Mucopolysaccharide Metabolism.
Autorzy :
Andonegui-Elguera S; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México; Departamento de Desarrollo Tecnológico, Instituto Nacional de Medicina Genómica, Ciudad de México, México.
Taniguchi-Ponciano K; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Gonzalez-Bonilla CR; Titular, Coordinación de Investigación en Salud, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Torres J; Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatria, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Mayani H; Unidad de Investigación Médica en Enfermedades Oncológicas, Hospital de Oncología, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Herrera LA; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, México; Dirección General, Instituto de Medicina Genómica, Ciudad de México, México.
Peña-Martínez E; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Silva-Román G; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Vela-Patiño S; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Ferreira-Hermosillo A; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México; Servicio de Endocrinología, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Ramirez-Renteria C; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México; Servicio de Endocrinología, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Carvente-Garcia R; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Mata-Lozano C; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Marrero-Rodríguez D; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México. Electronic address: .
Mercado M; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México. Electronic address: .
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Źródło :
Archives of medical research [Arch Med Res] 2020 Oct; Vol. 51 (7), pp. 645-653. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/diagnostic imaging
COVID-19*/genetics
COVID-19*/metabolism
COVID-19*/pathology
Glycosaminoglycans*/genetics
Glycosaminoglycans*/metabolism
Bronchoalveolar Lavage Fluid/cytology ; Humans ; Hyaluronic Acid/genetics ; Hyaluronic Acid/metabolism ; Leukocytes, Mononuclear/cytology ; Lung/diagnostic imaging ; Lung/pathology ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II.
Autorzy :
Wang J; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Bhalla A; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Ullman JC; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Fang M; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Ravi R; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Arguello A; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Thomsen E; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Tsogtbaatar B; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Guo JL; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Skuja LL; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Dugas JC; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Davis SS; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Poda SB; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Gunasekaran K; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Costanzo S; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Sweeney ZK; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Henry AG; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Harris JM; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Henne KR; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
Astarita G; Denali Therapeutics, Inc., 161 Oyster Point Blvd, South San Francisco, CA 94080, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 30; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers/*metabolism
Glycosaminoglycans/*isolation & purification
Iduronate Sulfatase/*genetics
Mucopolysaccharidosis II/*diagnosis
Animals ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/metabolism ; Brain/metabolism ; Brain/pathology ; Chromatography, Liquid ; Dermatan Sulfate/pharmacology ; Disaccharides/chemistry ; Disease Models, Animal ; Glycosaminoglycans/genetics ; Glycosaminoglycans/metabolism ; Heparitin Sulfate/pharmacology ; Humans ; Iduronate Sulfatase/metabolism ; Mice ; Mucopolysaccharidosis II/genetics ; Mucopolysaccharidosis II/pathology ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Biocompatibility and structural characterization of glycosaminoglycans isolated from heads of silver-banded whiting (Sillago argentifasciata Martin & Montalban 1935).
Autorzy :
Ticar BF; Natural Science Department, College of Arts and Sciences, Iloilo Science and Technology University, Burgos St., La Paz, Iloilo City 5000, Iloilo, Philippines. Electronic address: .
Rohmah Z; Faculty of Biology, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
Neri TAN; Department of Seafood Science and Technology, The Institute of Marine Industry, Gyeongsang National University, Tongyeong 53064, Republic of Korea.
Pahila IG; Iloilo Science and Technology University, Burgos St., La Paz, Iloilo City 5000, Iloilo, Philippines.
Vasconcelos A; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil.
Archer-Hartmann SA; Complex Carbohydrate Research Center, The University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
Reiter CEN; NAMSA, Northwood, OH 43619, USA.
Dobruchowska JM; Complex Carbohydrate Research Center, The University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
Choi BD; Department of Seafood Science and Technology, The Institute of Marine Industry, Gyeongsang National University, Tongyeong 53064, Republic of Korea.
Heiss C; Complex Carbohydrate Research Center, The University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
Azadi P; Complex Carbohydrate Research Center, The University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
Pomin VH; Department of Biomolecular Sciences, Pharmacognosy Division, Research Institute of Pharmaceutical Sciences School of Pharmacy, University of Mississippi, Oxford, MS 38677-1848, USA. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 May 15; Vol. 151, pp. 663-676. Date of Electronic Publication: 2020 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Biocompatible Materials/*chemistry
Glycosaminoglycans/*chemistry
Moths/*chemistry
Animals ; Biocompatible Materials/isolation & purification ; Biocompatible Materials/pharmacology ; Cell Line ; Chemical Fractionation ; Chromatography, Gel ; Glycosaminoglycans/isolation & purification ; Glycosaminoglycans/pharmacology ; Hyaluronic Acid/chemistry ; Mice ; Molecular Structure ; Spectrum Analysis
Czasopismo naukowe
Tytuł :
Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients.
Autorzy :
Bhalla A; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Ravi R; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Fang M; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Arguello A; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Davis SS; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Chiu CL; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Blumenfeld JR; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.; Department of Neuroscience, University of California, San Francisco, San Francisco, CA 94158, USA.
Nguyen HN; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Earr TK; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Wang J; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Astarita G; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Zhu Y; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Fiore D; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Scearce-Levie K; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Diaz D; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Cahan H; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Troyer MD; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Harris JM; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
Escolar ML; Department of Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA 15224, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 22; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Lipid Metabolism*
Brain/*metabolism
Glycosaminoglycans/*metabolism
Iduronate Sulfatase/*metabolism
Lysosomes/*metabolism
Mucopolysaccharidosis II/*blood
Mucopolysaccharidosis II/*cerebrospinal fluid
Adolescent ; Animals ; Biomarkers/metabolism ; Brain/pathology ; Child ; Child, Preschool ; Dermatan Sulfate/blood ; Dermatan Sulfate/cerebrospinal fluid ; Dermatan Sulfate/metabolism ; Enzyme Replacement Therapy ; Female ; Gangliosides/metabolism ; Glycosaminoglycans/cerebrospinal fluid ; Hematopoietic Stem Cell Transplantation ; Heparitin Sulfate/blood ; Heparitin Sulfate/cerebrospinal fluid ; Heparitin Sulfate/metabolism ; Humans ; Iduronate Sulfatase/genetics ; Iduronate Sulfatase/pharmacology ; Infant ; Inflammation/metabolism ; Lysosomes/pathology ; Male ; Mass Spectrometry ; Mice ; Mice, Knockout ; Mucopolysaccharidosis II/metabolism ; Mucopolysaccharidosis II/therapy ; Neurofilament Proteins/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
Anti-Tumor Effects of Biomimetic Sulfated Glycosaminoglycans on Lung Adenocarcinoma Cells in 2D and 3D In Vitro Models.
Autorzy :
Al Matari N; Department of Biomedical Engineering, Maroun Semaan Faculty of Engineering and Architecture, American University of Beirut, Beirut 1107 2020, Lebanon.
Deeb G; Department of Biomedical Engineering, Maroun Semaan Faculty of Engineering and Architecture, American University of Beirut, Beirut 1107 2020, Lebanon.
Mshiek H; Department of Anatomy, Cell Biology, and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
Sinjab A; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Kadara H; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Abou-Kheir W; Department of Anatomy, Cell Biology, and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
Mhanna R; Department of Biomedical Engineering, Maroun Semaan Faculty of Engineering and Architecture, American University of Beirut, Beirut 1107 2020, Lebanon.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Jun 03; Vol. 25 (11). Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Biomimetics*
Adenocarcinoma of Lung/*pathology
Alginates/*chemistry
Antineoplastic Agents/*pharmacology
Glycosaminoglycans/*pharmacology
Lung Neoplasms/*pathology
Sulfates/*chemistry
Adenocarcinoma of Lung/drug therapy ; Adenocarcinoma of Lung/metabolism ; Animals ; Antineoplastic Agents/chemistry ; Apoptosis ; Biomarkers/metabolism ; Cell Movement ; Cell Proliferation ; Glycosaminoglycans/chemistry ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/metabolism ; Mice ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Influence of galactosidases on glycosaminoglycan removal Vis-à-Vis opening up of skin matrix to enable complete rehydration.
Autorzy :
Jayanthi D; Academy of Scientific and Innovative Research (AcSIR), CSIR-CLRI Campus, CSIR - Central Leather Research Institute, Adyar, Chennai, 600020, India.; Leather Processing Division, CSIR - Central Leather Research Institute, Adyar, Chennai, 600020, India.
Victor JS; Leather Processing Division, CSIR - Central Leather Research Institute, Adyar, Chennai, 600020, India.
Chellan R; Department of Biotechnology, CSIR-CLRI, Chennai, India.
Chellappa M; Leather Processing Division, CSIR - Central Leather Research Institute, Adyar, Chennai, 600020, India. .
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Źródło :
Bioprocess and biosystems engineering [Bioprocess Biosyst Eng] 2020 Jun; Vol. 43 (6), pp. 1061-1070. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Glycosaminoglycans*/chemistry
Glycosaminoglycans*/metabolism
Aspergillus/*growth & development
Skin/*chemistry
Animals ; Goats
SCR Organism :
Aspergillus terreus
Czasopismo naukowe
Tytuł :
Intramural Glycosaminoglycans Distribution vs. Residual Stress in Porcine Ascending Aorta: a Computational Study
Autorzy :
Ghadie N
St-Pierre JP
Labrosse MR
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Źródło :
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2020 Jul; Vol. 2020, pp. 2816-2819.
Typ publikacji :
Journal Article
MeSH Terms :
Aorta*
Glycosaminoglycans*
Adventitia ; Animals ; Aortic Valve ; Stress, Mechanical ; Swine
Czasopismo naukowe
Tytuł :
New insights into the structure and function of chemokine receptor:chemokine complexes from an experimental perspective.
Autorzy :
Gustavsson M; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Jun; Vol. 107 (6), pp. 1115-1122. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Chemokines/*chemistry
Glycosaminoglycans/*chemistry
Receptors, Chemokine/*chemistry
Binding Sites ; Chemokines/genetics ; Chemokines/metabolism ; Crystallography, X-Ray/methods ; Gene Expression ; Glycosaminoglycans/metabolism ; HEK293 Cells ; Humans ; Models, Molecular ; Nuclear Magnetic Resonance, Biomolecular/methods ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Receptors, Chemokine/genetics ; Receptors, Chemokine/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Urinary glycosaminoglycans as a potential biomarker for evaluating treatment efficacy in subjects with mucopolysaccharidoses.
Autorzy :
Kakkis E; Ultragenyx Pharmaceutical Inc., Novato, CA, United States of America. Electronic address: .
Marsden D; Ultragenyx Pharmaceutical Inc., Novato, CA, United States of America.
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Źródło :
Molecular genetics and metabolism [Mol Genet Metab] 2020 May; Vol. 130 (1), pp. 7-15. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Enzyme Replacement Therapy*
Glycosaminoglycans/*urine
Mucopolysaccharidoses/*therapy
Animals ; Biomarkers/metabolism ; Biomarkers/urine ; Glycosaminoglycans/metabolism ; Humans ; Mucopolysaccharidoses/enzymology ; Mucopolysaccharidoses/physiopathology ; Mucopolysaccharidoses/urine ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Plasma and Urinary Glycosaminoglycans as Evidence for Endotheliopathy in a Swine Burn Model.
Autorzy :
Gómez BI; Damage Control Resuscitation, US Army Institute of Surgical Research, Houston, Texas.
Dubick MA; Damage Control Resuscitation, US Army Institute of Surgical Research, Houston, Texas.
Schmidt EP; Department of Medicine, University of Colorado Denver Department of Medicine, Denver Health Medical Center University of Colorado School of Medicine, Aurora, Colorado.
Shupp JW; The Burn Center, MedStar Washington Hospital Center, Department of Surgery, Biochemistry, Molecular and Cellular Biology Georgetown University School of Medicine, Washington, District of Columbia.
Burmeister DM; Damage Control Resuscitation, US Army Institute of Surgical Research, Houston, Texas. Electronic address: .
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Źródło :
The Journal of surgical research [J Surg Res] 2020 Apr; Vol. 248, pp. 28-37. Date of Electronic Publication: 2019 Dec 13.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Burns/*metabolism
Glycocalyx/*physiology
Glycosaminoglycans/*analysis
Acute Kidney Injury/diagnosis ; Acute Kidney Injury/therapy ; Animals ; Disease Models, Animal ; Endothelial Cells/physiology ; Glycosaminoglycans/blood ; Glycosaminoglycans/urine ; Kidney Tubules/pathology ; Lectins/analysis ; Rehydration Solutions/therapeutic use ; Swine ; Syndecan-1/analysis
Czasopismo naukowe
Tytuł :
Glycosaminoglycans from fresh water fish processing discard - Isolation, structural characterization, and osteogenic activity.
Autorzy :
Gavva C; Department of Molecular Nutrition, CSIR-CFTRI, Mysuru 570020, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-CFTRI campus, Mysuru 570020, Karnataka, India.
Patel K; Department of Molecular Nutrition, CSIR-CFTRI, Mysuru 570020, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-CFTRI campus, Mysuru 570020, Karnataka, India.
Kudre T; Meat and Marine Sciences, CSIR-CFTRI campus, Mysuru 570020, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-CFTRI campus, Mysuru 570020, Karnataka, India.
Sharan K; Department of Molecular Nutrition, CSIR-CFTRI, Mysuru 570020, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-CFTRI campus, Mysuru 570020, Karnataka, India.
Chilkunda DN; Department of Molecular Nutrition, CSIR-CFTRI, Mysuru 570020, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-CFTRI campus, Mysuru 570020, Karnataka, India. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Feb 15; Vol. 145, pp. 558-567. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji :
Journal Article
MeSH Terms :
Fishes*
Glycosaminoglycans/*chemistry
Glycosaminoglycans/*isolation & purification
Animals ; Biomarkers ; Calcification, Physiologic/drug effects ; Cell Differentiation ; Cell Line ; Cell Survival/drug effects ; Chromatography, Gel ; Chromatography, High Pressure Liquid ; Disaccharides/chemistry ; Fresh Water ; Glycosaminoglycans/pharmacology ; Hydrolysis ; Mice ; Molecular Weight ; Osteogenesis/drug effects ; Spectrum Analysis
Czasopismo naukowe

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