Autor: "Gnanapragasam, V. J." - OpacWWW - Prolib Integro

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Tytuł:: Identification of pathologically insignificant prostate cancer is not accurate in unscreened men.
Autorzy:: Shaw GL; 1] Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK [2] Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
Thomas BC; Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
Dawson SN; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
Srivastava G; Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
Vowler SL; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
Gnanapragasam VJ; Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
Shah NC; Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
Warren AY; Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
Neal DE; 1] Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK [2] Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2014 May 13; Vol. 110 (10), pp. 2405-11. Date of Electronic Publication: 2014 Apr 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Early Detection of Cancer*
Watchful Waiting*
Adenocarcinoma/*pathology
Prostate-Specific Antigen/*blood
Prostatic Neoplasms/*pathology
Adenocarcinoma/blood ; Adenocarcinoma/diagnosis ; Adenocarcinoma/surgery ; Aged ; Area Under Curve ; Biopsy, Needle ; False Negative Reactions ; Humans ; Lymphatic Metastasis ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; Organ Size ; Patient Selection ; Predictive Value of Tests ; Prostate/pathology ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/surgery ; ROC Curve ; Retrospective Studies ; Risk Assessment ; Seminal Vesicles/pathology ; Sensitivity and Specificity ; Tumor Burden

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Skocz do pozycji: 2.

Tytuł:: Changing presentation of prostate cancer in a UK population--10 year trends in prostate cancer risk profiles in the East of England.
Autorzy:: Greenberg DC; Public Health England, National Cancer Registration Service (Eastern Office), Cambridge CB22 3AD, UK.
Wright KA
Lophathanon A
Muir KR
Gnanapragasam VJ; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2013 Oct 15; Vol. 109 (8), pp. 2115-20. Date of Electronic Publication: 2013 Sep 26.
Typ publikacji:: Journal Article
MeSH Terms:: Prostatic Neoplasms/*diagnosis
Prostatic Neoplasms/*epidemiology
Age Factors ; Aged ; Aged, 80 and over ; England/epidemiology ; Humans ; Incidence ; Kallikreins/blood ; Male ; Middle Aged ; Neoplasm Grading ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/pathology ; Registries ; Risk Factors

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Tytuł:: Evidence for downregulation of the negative regulator SPRED2 in clinical prostate cancer.
Autorzy:: Kachroo N; Translational Prostate Cancer Group, Hutchison/MRC Research centre, University of Cambridge, Cambridge CB1 0XZ, UK.
Valencia T
Warren AY
Gnanapragasam VJ; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2013 Feb 19; Vol. 108 (3), pp. 597-601. Date of Electronic Publication: 2012 Nov 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dual Specificity Phosphatase 1/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
Membrane Proteins/*genetics
Prostatic Hyperplasia/*genetics
Prostatic Neoplasms/*genetics
Receptors, Interleukin/*genetics
Repressor Proteins/*genetics
Adaptor Proteins, Signal Transducing ; Blotting, Western ; Cell Movement ; Cell Proliferation ; Cohort Studies ; Down-Regulation ; Dual Specificity Phosphatase 1/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Male ; Membrane Proteins/metabolism ; Neoplasm Grading ; Prognosis ; Prostatic Hyperplasia/metabolism ; Prostatic Hyperplasia/pathology ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; RNA, Messenger/genetics ; RNA, Small Interfering/genetics ; Real-Time Polymerase Chain Reaction ; Receptors, Interleukin/metabolism ; Repressor Proteins/antagonists & inhibitors ; Repressor Proteins/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction ; Tumor Cells, Cultured

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Skocz do pozycji: 4.

Tytuł:: Risk profiles of prostate cancers identified from UK primary care using national referral guidelines.
Autorzy:: Serag H; Department of Urology, Addenbrookes Hospital, Hills Road, Cambridge CB2 0XZ, UK.
Banerjee S
Saeb-Parsy K
Irving S
Wright K
Stearn S
Doble A
Gnanapragasam VJ; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2012 Jan 31; Vol. 106 (3), pp. 436-9. Date of Electronic Publication: 2012 Jan 12.
Typ publikacji:: Journal Article; Multicenter Study
MeSH Terms:: Benchmarking*
Practice Guidelines as Topic*
Referral and Consultation*
Prostatic Neoplasms/*epidemiology
State Medicine/*standards
Aged ; Cohort Studies ; Early Detection of Cancer/statistics & numerical data ; England/epidemiology ; Humans ; Male ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Staging ; Prospective Studies ; Prostatic Neoplasms/etiology ; Prostatic Neoplasms/pathology ; Registries ; Risk Factors

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Tytuł:: Similar expression to FGF (Sef) inhibits fibroblast growth factor-induced tumourigenic behaviour in prostate cancer cells and is downregulated in aggressive clinical disease.
Autorzy:: Darby S; Northern Institute for Cancer Research, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK.
Murphy T
Thomas H
Robson CN
Leung HY
Mathers ME
Gnanapragasam VJ; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2009 Dec 01; Vol. 101 (11), pp. 1891-9. Date of Electronic Publication: 2009 Nov 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Fibroblast Growth Factors/*antagonists & inhibitors
Prostatic Neoplasms/*metabolism
Receptors, Interleukin/*biosynthesis
Animals ; Cell Growth Processes/physiology ; Cell Line, Tumor ; Down-Regulation ; Fibroblast Growth Factors/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Mice ; Mice, Nude ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; Receptor Protein-Tyrosine Kinases/metabolism ; Receptors, Interleukin/genetics ; Receptors, Interleukin/metabolism ; Signal Transduction ; Transfection

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Skocz do pozycji: 6.

Tytuł:: FGF8 isoform b expression in human prostate cancer.
Autorzy:: Gnanapragasam VJ; Prostate Research Group, School of Surgical Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK. V.J. />Robinson MC
Marsh C
Robson CN
Hamdy FC
Leung HY; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2003 May 06; Vol. 88 (9), pp. 1432-8.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Fibroblast Growth Factors/*genetics
Prostatic Neoplasms/*pathology
Fibroblast Growth Factor 8 ; Fibroblast Growth Factors/analysis ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Neoplasm Staging ; Prognosis ; Prostatic Neoplasms/genetics ; Protein Isoforms/analysis ; Protein Isoforms/genetics ; RNA, Messenger/analysis ; RNA, Messenger/genetics

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Skocz do pozycji: 7.

Tytuł:: Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer.
Autorzy:: Gnanapragasam VJ; Prostate Research Group, School of Surgical Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Leung HY
Pulimood AS
Neal DE
Robson CN; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2001 Dec 14; Vol. 85 (12), pp. 1928-36.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Androgens*
Transcription Factors*
Adenocarcinoma/*metabolism
Neoplasm Proteins/*biosynthesis
Neoplasms, Hormone-Dependent/*metabolism
Prostatic Neoplasms/*metabolism
Trans-Activators/*biosynthesis
Adenocarcinoma/genetics ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/blood ; Disease Progression ; Epithelial Cells/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; In Situ Hybridization ; Male ; Middle Aged ; Neoplasm Proteins/genetics ; Neoplasm Staging ; Neoplasms, Hormone-Dependent/genetics ; Neoplasms, Hormone-Dependent/pathology ; Nuclear Receptor Coactivator 3 ; Prostate-Specific Antigen/blood ; Prostatic Hyperplasia/metabolism ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; RNA, Neoplasm/biosynthesis ; RNA, Neoplasm/genetics ; Receptors, Androgen/metabolism ; Trans-Activators/genetics ; Transcription, Genetic ; Transfection ; Tumor Cells, Cultured/metabolism

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