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Tytuł :
Physiology of Parathyroid Hormone.
Autorzy :
Goltzman D; Department of Medicine and Research Institute of the McGill University Health Centre, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada; Departments of Medicine and of Physiology, McGill University, 845 Sherbrooke St West, Montreal, Quebec H3A 0B9, Canada. Electronic address: david.goltzman@mcgill.ca.
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Źródło :
Endocrinology and metabolism clinics of North America [Endocrinol Metab Clin North Am] 2018 Dec; Vol. 47 (4), pp. 743-758. Date of Electronic Publication: 2018 Oct 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Parathyroid Glands/*physiology
Parathyroid Hormone/*physiology
Animals ; Bone and Bones/metabolism ; Bone and Bones/physiology ; Calcium/metabolism ; Hormone Replacement Therapy ; Humans ; Kidney/metabolism ; Kidney/physiology ; Phosphates/metabolism
Czasopismo naukowe
Tytuł :
Physiology of the Calcium-Parathyroid Hormone-Vitamin D Axis.
Autorzy :
Goltzman D
Mannstadt M
Marcocci C
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Źródło :
Frontiers of hormone research [Front Horm Res] 2018; Vol. 50, pp. 1-13. Date of Electronic Publication: 2018 Mar 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Calcium/*metabolism
Homeostasis/*physiology
Parathyroid Hormone/*metabolism
Vitamin D/*analogs & derivatives
Humans ; Vitamin D/metabolism
Czasopismo naukowe
Tytuł :
Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis.
Autorzy :
Hirai T; Endocrine Unit (T.H., T.K., S.N., H.M.K.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Sir Mortimer B. Davis Jewish General Hospital (A.C.K.), McGill University, Montreal, Québec, Canada H3T 1E2; and Royal Victoria Hospital of the McGill University Health Centre (D.G.), Montreal, Québec, Canada H3A 1A1.
Kobayashi T; Endocrine Unit (T.H., T.K., S.N., H.M.K.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Sir Mortimer B. Davis Jewish General Hospital (A.C.K.), McGill University, Montreal, Québec, Canada H3T 1E2; and Royal Victoria Hospital of the McGill University Health Centre (D.G.), Montreal, Québec, Canada H3A 1A1.
Nishimori S; Endocrine Unit (T.H., T.K., S.N., H.M.K.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Sir Mortimer B. Davis Jewish General Hospital (A.C.K.), McGill University, Montreal, Québec, Canada H3T 1E2; and Royal Victoria Hospital of the McGill University Health Centre (D.G.), Montreal, Québec, Canada H3A 1A1.
Karaplis AC; Endocrine Unit (T.H., T.K., S.N., H.M.K.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Sir Mortimer B. Davis Jewish General Hospital (A.C.K.), McGill University, Montreal, Québec, Canada H3T 1E2; and Royal Victoria Hospital of the McGill University Health Centre (D.G.), Montreal, Québec, Canada H3A 1A1.
Goltzman D; Endocrine Unit (T.H., T.K., S.N., H.M.K.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Sir Mortimer B. Davis Jewish General Hospital (A.C.K.), McGill University, Montreal, Québec, Canada H3T 1E2; and Royal Victoria Hospital of the McGill University Health Centre (D.G.), Montreal, Québec, Canada H3A 1A1.
Kronenberg HM; Endocrine Unit (T.H., T.K., S.N., H.M.K.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Sir Mortimer B. Davis Jewish General Hospital (A.C.K.), McGill University, Montreal, Québec, Canada H3T 1E2; and Royal Victoria Hospital of the McGill University Health Centre (D.G.), Montreal, Québec, Canada H3A 1A1.
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Źródło :
Endocrinology [Endocrinology] 2015 Aug; Vol. 156 (8), pp. 2774-80. Date of Electronic Publication: 2015 Jun 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Homeostasis*/genetics
Bone and Bones/*metabolism
Calcium/*blood
Fetal Blood/*metabolism
Parathyroid Hormone/*physiology
Parathyroid Hormone-Related Protein/*physiology
Animals ; Embryo, Mammalian ; Female ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Parathyroid Hormone/genetics ; Parathyroid Hormone-Related Protein/genetics ; Pregnancy ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
The calcium-sensing receptor in bone--mechanistic and therapeutic insights.
Autorzy :
Goltzman D; Department of Medicine, McGill University, 687 Pine Avenue West, Montreal, QC H3A 1A1, Canada.
Hendy GN; Department of Medicine, McGill University, 687 Pine Avenue West, Montreal, QC H3A 1A1, Canada.
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Źródło :
Nature reviews. Endocrinology [Nat Rev Endocrinol] 2015 May; Vol. 11 (5), pp. 298-307. Date of Electronic Publication: 2015 Mar 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Bone Development*
Bone Diseases, Metabolic/*metabolism
Bone and Bones/*metabolism
Parathyroid Hormone/*metabolism
Receptors, Calcium-Sensing/*metabolism
Animals ; Bone Diseases, Metabolic/therapy ; Bone Remodeling ; Calcification, Physiologic ; Calcium/metabolism ; Cartilage/metabolism ; Chondrocytes/metabolism ; Homeostasis ; Humans ; Osteoblasts/metabolism ; Osteoclasts/metabolism ; Receptors, Calcium-Sensing/genetics
Czasopismo naukowe
Tytuł :
In healthy adults, biological activity of vitamin D, as assessed by serum PTH, is largely independent of DBP concentrations.
Autorzy :
Dastani Z; Department of Human Genetics and Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada.
Berger C
Langsetmo L
Fu L
Wong BY
Malik S
Goltzman D
Cole DE
Richards JB
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Źródło :
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2014 Feb; Vol. 29 (2), pp. 494-9.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Body Mass Index*
Parathyroid Hormone/*blood
Vitamin D/*analogs & derivatives
Vitamin D-Binding Protein/*blood
Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Vitamin D/blood
Czasopismo naukowe
Tytuł :
Endogenous parathyroid hormone-related protein compensates for the absence of parathyroid hormone in promoting bone accrual in vivo in a model of bone marrow ablation.
Autorzy :
Zhu Q; The State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Zhou X
Zhu M
Wang Q
Goltzman D
Karaplis A
Miao D
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Źródło :
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2013 Sep; Vol. 28 (9), pp. 1898-911.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ablation Techniques*
Bone Marrow/*pathology
Bone Marrow/*surgery
Bone and Bones/*metabolism
Parathyroid Hormone/*deficiency
Parathyroid Hormone-Related Protein/*metabolism
Animals ; Apoptosis/genetics ; Bone Marrow/metabolism ; Bone Remodeling ; Bone Resorption/genetics ; Bone Resorption/pathology ; Bone and Bones/pathology ; Disease Models, Animal ; Gene Expression Regulation ; Haploinsufficiency ; Mice ; Mice, Inbred C57BL ; Osteoblasts/metabolism ; Osteoblasts/pathology ; Osteoclasts/metabolism ; Osteoclasts/pathology ; Osteogenesis ; Parathyroid Hormone/metabolism ; Parathyroid Hormone-Related Protein/deficiency ; Receptor, Parathyroid Hormone, Type 1/metabolism ; Receptors, Calcium-Sensing ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł :
Parathyroid hormone ablation alters erythrocyte parameters that are rescued by calcium-sensing receptor gene deletion.
Autorzy :
Romero JR; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Youte R
Brown EM
Pollak MR
Goltzman D
Karaplis A
Pong LC
Chien L
Chattopadhyay N
Rivera A
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Źródło :
European journal of haematology [Eur J Haematol] 2013 Jul; Vol. 91 (1), pp. 37-45. Date of Electronic Publication: 2013 Apr 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Deletion*
Erythrocytes/*metabolism
Parathyroid Hormone/*metabolism
Receptors, Calcium-Sensing/*genetics
Animals ; Calcium/metabolism ; Cations ; Cell Membrane/metabolism ; Cell Membrane Permeability ; Erythrocytes/cytology ; Homeostasis ; Mice ; Mice, Knockout ; Osmosis ; Phenotype
Czasopismo naukowe
Tytuł :
Bone marrow ablation demonstrates that excess endogenous parathyroid hormone plays distinct roles in trabecular and cortical bone.
Autorzy :
Yan J; Department of Orthopedics, Second Affiliated Hospital of Soochow University, Suzhou, China.
Sun W
Zhang J
Goltzman D
Miao D
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Źródło :
The American journal of pathology [Am J Pathol] 2012 Jul; Vol. 181 (1), pp. 234-44. Date of Electronic Publication: 2012 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Remodeling/*physiology
Osteogenesis/*physiology
Parathyroid Hormone/*physiology
25-Hydroxyvitamin D3 1-alpha-Hydroxylase/deficiency ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/genetics ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/physiology ; Ablation Techniques ; Animals ; Bone Marrow/physiology ; Bone Marrow/surgery ; Bone Resorption/physiopathology ; Calcium/blood ; Femur/diagnostic imaging ; Mice ; Mice, Knockout ; Osteoclasts/pathology ; Osteoprotegerin/biosynthesis ; Parathyroid Hormone/blood ; Phosphorus/blood ; RANK Ligand/biosynthesis ; X-Ray Microtomography/methods
Czasopismo naukowe
Tytuł :
Temporal trends and determinants of longitudinal change in 25-hydroxyvitamin D and parathyroid hormone levels.
Autorzy :
Berger C; CaMos Coordinating Centre, McGill University, 687 Pine Avenue West, Montréal, Québec, Canada.
Greene-Finestone LS
Langsetmo L
Kreiger N
Joseph L
Kovacs CS
Richards JB
Hidiroglou N
Sarafin K
Davison KS
Adachi JD
Brown J
Hanley DA
Prior JC
Goltzman D
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Corporate Authors :
CaMos Research Group
Źródło :
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2012 Jun; Vol. 27 (6), pp. 1381-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Parathyroid Hormone/*blood
Vitamin D/*analogs & derivatives
Adult ; Aged ; Calcium/pharmacology ; Dietary Supplements ; Female ; Follow-Up Studies ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Seasons ; Time Factors ; Vitamin D/blood ; Vitamin D/pharmacology
Czasopismo naukowe
Tytuł :
The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice.
Autorzy :
Xue Y; Calcium Research Laboratory, McGill University Health Centre, Montreal, QC, Canada.
Xiao Y
Liu J
Karaplis AC
Pollak MR
Brown EM
Miao D
Goltzman D
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2012 Apr 01; Vol. 302 (7), pp. E841-51. Date of Electronic Publication: 2012 Jan 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone and Bones/*metabolism
Parathyroid Hormone/*pharmacology
Receptors, Calcium-Sensing/*metabolism
Absorptiometry, Photon ; Acid Phosphatase/metabolism ; Animals ; Bone Density/physiology ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/metabolism ; Bone and Bones/drug effects ; Bone and Bones/pathology ; Cells, Cultured ; Female ; Femur/diagnostic imaging ; Gene Expression Regulation ; Hyperparathyroidism/metabolism ; Hyperparathyroidism/pathology ; Isoenzymes/metabolism ; Male ; Mice ; Mice, Knockout ; NF-kappa B/metabolism ; Porosity ; RNA/biosynthesis ; RNA/genetics ; Real-Time Polymerase Chain Reaction ; Receptors, Calcium-Sensing/genetics ; Tartrate-Resistant Acid Phosphatase ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus, and PTH.
Autorzy :
Liu J; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and Embryology, Nanjing Medical University, Nanjing, China.
Lv F
Sun W
Tao C
Ding G
Karaplis A
Brown E
Goltzman D
Miao D
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Źródło :
PLoS genetics [PLoS Genet] 2011 Sep; Vol. 7 (9), pp. e1002294. Date of Electronic Publication: 2011 Sep 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone and Bones/*abnormalities
Calcium/*metabolism
Cartilage/*abnormalities
Hyperparathyroidism/*genetics
Osteoblasts/*metabolism
Parathyroid Hormone/*genetics
Phosphorus/*metabolism
Receptors, Calcium-Sensing/*genetics
Animals ; Bone and Bones/metabolism ; Calcium/blood ; Cartilage/metabolism ; Cell Proliferation ; Chondrocytes/metabolism ; Homozygote ; Hyperparathyroidism/metabolism ; Mice ; Mice, Mutant Strains ; Osteogenesis/genetics ; Parathyroid Hormone/blood ; Phosphorus/blood ; Receptors, Calcium-Sensing/deficiency ; Steroid Hydroxylases/genetics ; Steroid Hydroxylases/metabolism
Czasopismo naukowe
Tytuł :
The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates.
Autorzy :
Shu L; Laboratory of Reproductive Medicine, Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Ji J
Zhu Q
Cao G
Karaplis A
Pollak MR
Brown E
Goltzman D
Miao D
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Źródło :
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2011 May; Vol. 26 (5), pp. 1057-71.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Remodeling/*drug effects
Calcium, Dietary/*pharmacology
Parathyroid Hormone/*pharmacology
Receptors, Calcium-Sensing/*metabolism
Animals ; Animals, Newborn ; Bone Density/drug effects ; Bone Resorption/pathology ; Calcitriol/blood ; Calcium/blood ; Calcium/urine ; Cell Lineage/drug effects ; Hormones/metabolism ; Intestinal Mucosa/metabolism ; Intestines/drug effects ; Membrane Transport Proteins/metabolism ; Mice ; Milk/chemistry ; Organ Size/drug effects ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Osteogenesis/drug effects ; Parathyroid Hormone/blood ; Parathyroid Hormone/deficiency ; Phosphorus/blood ; Receptors, Calcium-Sensing/deficiency ; Signal Transduction/drug effects ; Stem Cells/cytology ; Stem Cells/drug effects ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34).
Autorzy :
Ren Y; Department of Orthopaedics, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
Liu B
Feng Y
Shu L
Cao X
Karaplis A
Goltzman D
Miao D
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Źródło :
PloS one [PLoS One] 2011; Vol. 6 (7), pp. e23060. Date of Electronic Publication: 2011 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bony Callus/*drug effects
Fracture Healing/*drug effects
Fractures, Bone/*pathology
Parathyroid Hormone/*pharmacology
Parathyroid Hormone/*physiology
Wound Healing/*drug effects
Animals ; Blotting, Western ; Bone Resorption/drug therapy ; Bone Resorption/pathology ; Fractures, Bone/drug therapy ; Immunoenzyme Techniques ; Mice ; Mice, Knockout ; RNA, Messenger/genetics ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Emerging roles for calcium-regulating hormones beyond osteolysis.
Autorzy :
Goltzman D; Calcium Research Laboratory, Departments of Medicine, McGill University and McGill University Health Centre, Montreal, QC H3A1A1, Canada. david.goltzman@mcgill.ca
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Źródło :
Trends in endocrinology and metabolism: TEM [Trends Endocrinol Metab] 2010 Aug; Vol. 21 (8), pp. 512-8. Date of Electronic Publication: 2010 May 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Calcitriol/*physiology
Growth Plate/*physiology
Osteogenesis/*physiology
Parathyroid Hormone/*physiology
Parathyroid Hormone-Related Protein/*physiology
Animals ; Autocrine Communication ; Bone Diseases/genetics ; Bone Diseases/physiopathology ; Bone and Bones/physiology ; Calcitriol/genetics ; Calcium/metabolism ; Humans ; Metabolism, Inborn Errors/genetics ; Metabolism, Inborn Errors/physiopathology ; Osteolysis/physiopathology ; Parathyroid Hormone/genetics ; Parathyroid Hormone-Related Protein/genetics
Czasopismo naukowe
Tytuł :
Basal bone phenotype and increased anabolic responses to intermittent parathyroid hormone in healthy male COX-2 knockout mice.
Autorzy :
Xu M; Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.
Choudhary S
Voznesensky O
Gao Q
Adams D
Diaz-Doran V
Wu Q
Goltzman D
Raisz LG
Pilbeam CC
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Źródło :
Bone [Bone] 2010 Aug; Vol. 47 (2), pp. 341-52. Date of Electronic Publication: 2010 May 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Health*
Cyclooxygenase 2/*deficiency
Femur/*drug effects
Femur/*pathology
Parathyroid Hormone/*pharmacology
Animals ; Biomarkers/blood ; Body Weight/drug effects ; Bone Remodeling/drug effects ; Cyclooxygenase 1/genetics ; Cyclooxygenase 1/metabolism ; Cyclooxygenase 2/metabolism ; Femur/diagnostic imaging ; Femur/enzymology ; Gene Expression Profiling ; Gene Expression Regulation/drug effects ; Humans ; Hyperthyroidism/blood ; Hyperthyroidism/genetics ; Hyperthyroidism/physiopathology ; Kidney/drug effects ; Kidney/physiopathology ; Male ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Mice, Knockout ; Organ Size/drug effects ; Osteoprotegerin/genetics ; Osteoprotegerin/metabolism ; Phenotype ; RANK Ligand/genetics ; RANK Ligand/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Radiography
Czasopismo naukowe
Tytuł :
Distinctive anabolic roles of 1,25-dihydroxyvitamin D(3) and parathyroid hormone in teeth and mandible versus long bones.
Autorzy :
Liu H; Institute of Dental Research, Stomatological College The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, Jiangsu 210029, People's Republic of China.
Guo J
Wang L
Chen N
Karaplis A
Goltzman D
Miao D
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Źródło :
The Journal of endocrinology [J Endocrinol] 2009 Nov; Vol. 203 (2), pp. 203-13. Date of Electronic Publication: 2009 Aug 27.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Development*
Calcitriol/*physiology
Mandible/*growth & development
Parathyroid Hormone/*physiology
Tooth/*growth & development
Animals ; Calcification, Physiologic ; Dentin/growth & development ; Mice ; Receptors, Calcitriol/physiology ; Tooth Calcification
Czasopismo naukowe
Tytuł :
The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion.
Autorzy :
Kantham L; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA. />Quinn SJ
Egbuna OI
Baxi K
Butters R
Pang JL
Pollak MR
Goltzman D
Brown EM
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2009 Oct; Vol. 297 (4), pp. E915-23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hypercalcemia/*physiopathology
Parathyroid Hormone/*physiology
Receptors, Calcium-Sensing/*physiology
Amino Acids/urine ; Animals ; Bone and Bones/metabolism ; Calcifediol/metabolism ; Calcitonin/blood ; Calcium/blood ; Calcium/pharmacology ; Calcium/urine ; Drug Implants ; Homeostasis/genetics ; Homeostasis/physiology ; Kidney/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Osteocalcin/blood ; Parathyroid Hormone/genetics ; Parathyroid Hormone/pharmacology ; Phosphates/deficiency ; Receptors, Calcium-Sensing/genetics
Czasopismo naukowe
Tytuł :
The full-length calcium-sensing receptor dampens the calcemic response to 1alpha,25(OH)2 vitamin D3 in vivo independently of parathyroid hormone.
Autorzy :
Egbuna O; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. />Quinn S
Kantham L
Butters R
Pang J
Pollak M
Goltzman D
Brown E
Pokaż więcej
Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2009 Sep; Vol. 297 (3), pp. F720-8. Date of Electronic Publication: 2009 May 27.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Duodenum/*metabolism
Ergocalciferols/*pharmacokinetics
Kidney/*metabolism
Parathyroid Hormone/*metabolism
Receptors, Calcium-Sensing/*metabolism
Animals ; Calcitonin/metabolism ; Calcium/blood ; Calcium/urine ; Calcium, Dietary/administration & dosage ; Calcium, Dietary/metabolism ; Creatinine/urine ; Diphosphonates/pharmacology ; Duodenum/drug effects ; Ergocalciferols/administration & dosage ; Ergocalciferols/blood ; Gene Expression Regulation ; Genotype ; Injections, Intraperitoneal ; Intestinal Absorption ; Kidney/drug effects ; Mice ; Mice, Knockout ; Pamidronate ; Parathyroid Hormone/deficiency ; Parathyroid Hormone/genetics ; Phenotype ; Receptors, Calcium-Sensing/deficiency ; Receptors, Calcium-Sensing/genetics
Czasopismo naukowe
Tytuł :
Parathyroid hormone contributes to regulating milk calcium content and modulates neonatal bone formation cooperatively with calcium.
Autorzy :
Cao G; Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, Jiangsu, PR China.
Gu Z
Ren Y
Shu L
Tao C
Karaplis A
Goltzman D
Miao D
Pokaż więcej
Źródło :
Endocrinology [Endocrinology] 2009 Feb; Vol. 150 (2), pp. 561-9. Date of Electronic Publication: 2008 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Milk/*metabolism
Osteogenesis/*genetics
Parathyroid Hormone/*physiology
Animals ; Animals, Newborn ; Animals, Suckling ; Bone Density/genetics ; Calcium/analysis ; Calcium/blood ; Calcium/physiology ; Cholecalciferol/analysis ; Cholecalciferol/metabolism ; Drug Synergism ; Eating/genetics ; Female ; Growth/genetics ; Lactation/genetics ; Lactation/metabolism ; Male ; Mice ; Mice, Transgenic ; Milk/chemistry ; Osteoblasts/metabolism ; Osteoblasts/physiology ; Osteogenesis/physiology ; Parathyroid Hormone/genetics ; Parathyroid Hormone/metabolism ; Parathyroid Hormone-Related Protein/analysis ; Parathyroid Hormone-Related Protein/metabolism
Czasopismo naukowe
Tytuł :
Exogenous PTH and endogenous 1,25-dihydroxyvitamin D are complementary in inducing an anabolic effect on bone.
Autorzy :
Samadfam R; Calcium Research Laboratory and Department of Medicine, McGill University Health Centre and McGill University, Montreal, Quebec, Canada.
Xia Q
Miao D
Hendy GN
Goltzman D
Pokaż więcej
Źródło :
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2008 Aug; Vol. 23 (8), pp. 1257-66.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone and Bones/*drug effects
Bone and Bones/*metabolism
Parathyroid Hormone/*pharmacology
Vitamin D/*analogs & derivatives
25-Hydroxyvitamin D3 1-alpha-Hydroxylase/deficiency ; Animals ; Biomarkers/metabolism ; Bone Density/drug effects ; Bone Resorption/metabolism ; Calcium/blood ; Densitometry ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Organ Size/drug effects ; Osteoblasts/drug effects ; Osteoblasts/enzymology ; Osteogenesis/drug effects ; Parathyroid Hormone/administration & dosage ; Phosphorus/blood ; Tibia/cytology ; Tibia/drug effects ; Tomography, X-Ray Computed ; Vitamin D/metabolism
Czasopismo naukowe

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