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Wyświetlanie 1-53 z 53
Tytuł:
Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation.
Autorzy:
Li J; Department of Plastic Surgery, Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.
Zhang J; Department of Plastic Surgery, Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.
Xue Q; Department of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China.
Liu B; Department of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China.
Qin R; Department of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China.
Li Y; Department of Plastic Surgery, Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.
Qiu Y; Department of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China.
Wang R; Department of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China.
Goltzman D; Calcium Research Laboratory, McGill University Health Centre and Department of Medicine, McGill University, Montreal, Quebec, Canada.
Miao D; Department of Plastic Surgery, Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.
Yang R; Department of Plastic Surgery, Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.
Pokaż więcej
Źródło:
Aging cell [Aging Cell] 2023 Sep; Vol. 22 (9), pp. e13912. Date of Electronic Publication: 2023 Jun 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Osteoporosis*/drug therapy
Osteoporosis*/metabolism
Bone Resorption*/drug therapy
Mice ; Animals ; Antioxidants/metabolism ; PQQ Cofactor/pharmacology ; PQQ Cofactor/metabolism ; PQQ Cofactor/therapeutic use ; NF-E2-Related Factor 2/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; Up-Regulation ; Fibrillin-1/metabolism ; Molecular Docking Simulation ; Oxidative Stress ; Aging
Czasopismo naukowe
Tytuł:
1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis.
Autorzy:
Yang R; The Research Center for Aging, Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Chen J; Department of Anesthesiology, Central South University, Changsha, China.
Zhang J; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Qin R; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Wang R; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Qiu Y; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Mao Z; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Goltzman D; Calcium Research Laboratory, McGill University Health Centre and Department of Medicine, McGill University, Montreal, Quebec, Canada.
Miao D; The Research Center for Aging, Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.; State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.
Pokaż więcej
Źródło:
Aging cell [Aging Cell] 2020 Feb; Vol. 19 (2), pp. e13095. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
25-Hydroxyvitamin D3 1-alpha-Hydroxylase/*metabolism
Cyclin-Dependent Kinase Inhibitor p16/*metabolism
Mesenchymal Stem Cells/*drug effects
Osteoporosis/*drug therapy
Receptors, Calcitriol/*metabolism
Vitamin D/*analogs & derivatives
25-Hydroxyvitamin D3 1-alpha-Hydroxylase/genetics ; Aging/genetics ; Animals ; Bone and Bones/diagnostic imaging ; Bone and Bones/drug effects ; Bone and Bones/metabolism ; Bone and Bones/physiopathology ; Cells, Cultured ; Cyclin-Dependent Kinase Inhibitor p19/metabolism ; DNA Damage/genetics ; Enhancer of Zeste Homolog 2 Protein/metabolism ; Female ; Histones/metabolism ; Male ; Mesenchymal Stem Cells/metabolism ; Mice ; Mice, Knockout ; Osteocytes/drug effects ; Osteocytes/metabolism ; Osteogenesis/genetics ; Osteoporosis/enzymology ; Osteoporosis/metabolism ; Osteoporosis/physiopathology ; Oxidative Stress/genetics ; Receptors, Calcitriol/genetics ; Vitamin D/pharmacology ; Vitamin D/therapeutic use
Czasopismo naukowe
Tytuł:
The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development.
Autorzy:
Camirand A; McGill University Health Centre, Montréal, Québec, Canada.
Goltzman D; McGill University Health Centre, Montréal, Québec, Canada.
Gupta A; Department of Oncology, McGill University, Montreal, Québec, Canada.
Kaouass M; Department of Biology, Université Sainte-Anne, Pointe-de-l'Eglise, Nova Scotia, Canada.
Panda D; Lady Davis Institute, Jewish General Hospital, Montréal, Québec, Canada.
Karaplis A; Lady Davis Institute, Jewish General Hospital, Montréal, Québec, Canada.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2016 Jul 27; Vol. 11 (7), pp. e0160034. Date of Electronic Publication: 2016 Jul 27 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Osteoblasts/*metabolism
Osteoporosis/*metabolism
Parathyroid Hormone-Related Protein/*metabolism
Weightlessness/*adverse effects
Animals ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Cells, Cultured ; Extracellular Matrix Proteins/genetics ; Extracellular Matrix Proteins/metabolism ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Osteoporosis/etiology ; Parathyroid Hormone-Related Protein/genetics ; Prolactin/genetics ; Prolactin/metabolism
Czasopismo naukowe
Tytuł:
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Autorzy:
Estrada K; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Styrkarsdottir U
Evangelou E
Hsu YH
Duncan EL
Ntzani EE
Oei L
Albagha OM
Amin N
Kemp JP
Koller DL
Li G
Liu CT
Minster RL
Moayyeri A
Vandenput L
Willner D
Xiao SM
Yerges-Armstrong LM
Zheng HF
Alonso N
Eriksson J
Kammerer CM
Kaptoge SK
Leo PJ
Thorleifsson G
Wilson SG
Wilson JF
Aalto V
Alen M
Aragaki AK
Aspelund T
Center JR
Dailiana Z
Duggan DJ
Garcia M
Garcia-Giralt N
Giroux S
Hallmans G
Hocking LJ
Husted LB
Jameson KA
Khusainova R
Kim GS
Kooperberg C
Koromila T
Kruk M
Laaksonen M
Lacroix AZ
Lee SH
Leung PC
Lewis JR
Masi L
Mencej-Bedrac S
Nguyen TV
Nogues X
Patel MS
Prezelj J
Rose LM
Scollen S
Siggeirsdottir K
Smith AV
Svensson O
Trompet S
Trummer O
van Schoor NM
Woo J
Zhu K
Balcells S
Brandi ML
Buckley BM
Cheng S
Christiansen C
Cooper C
Dedoussis G
Ford I
Frost M
Goltzman D
González-Macías J
Kähönen M
Karlsson M
Khusnutdinova E
Koh JM
Kollia P
Langdahl BL
Leslie WD
Lips P
Ljunggren Ö
Lorenc RS
Marc J
Mellström D
Obermayer-Pietsch B
Olmos JM
Pettersson-Kymmer U
Reid DM
Riancho JA
Ridker PM
Rousseau F
Slagboom PE
Tang NL
Urreizti R
Van Hul W
Viikari J
Zarrabeitia MT
Aulchenko YS
Castano-Betancourt M
Grundberg E
Herrera L
Ingvarsson T
Johannsdottir H
Kwan T
Li R
Luben R
Medina-Gómez C
Palsson ST
Reppe S
Rotter JI
Sigurdsson G
van Meurs JB
Verlaan D
Williams FM
Wood AR
Zhou Y
Gautvik KM
Pastinen T
Raychaudhuri S
Cauley JA
Chasman DI
Clark GR
Cummings SR
Danoy P
Dennison EM
Eastell R
Eisman JA
Gudnason V
Hofman A
Jackson RD
Jones G
Jukema JW
Khaw KT
Lehtimäki T
Liu Y
Lorentzon M
McCloskey E
Mitchell BD
Nandakumar K
Nicholson GC
Oostra BA
Peacock M
Pols HA
Prince RL
Raitakari O
Reid IR
Robbins J
Sambrook PN
Sham PC
Shuldiner AR
Tylavsky FA
van Duijn CM
Wareham NJ
Cupples LA
Econs MJ
Evans DM
Harris TB
Kung AW
Psaty BM
Reeve J
Spector TD
Streeten EA
Zillikens MC
Thorsteinsdottir U
Ohlsson C
Karasik D
Richards JB
Brown MA
Stefansson K
Uitterlinden AG
Ralston SH
Ioannidis JP
Kiel DP
Rivadeneira F
Pokaż więcej
Źródło:
Nature genetics [Nat Genet] 2012 Apr 15; Vol. 44 (5), pp. 491-501. Date of Electronic Publication: 2012 Apr 15.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Quantitative Trait Loci*
Bone Density/*genetics
Fractures, Bone/*genetics
Osteoporosis/*genetics
Polymorphism, Single Nucleotide/*genetics
Computational Biology ; Extracellular Matrix Proteins/genetics ; Female ; Femur Neck/physiopathology ; Gene Expression Profiling ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Genotype ; Glycoproteins/genetics ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Low Density Lipoprotein Receptor-Related Protein-5/genetics ; Lumbar Vertebrae/physiopathology ; Male ; Mitochondrial Membrane Transport Proteins/genetics ; Phosphoproteins/genetics ; Risk Factors ; Spectrin/genetics ; White People
Czasopismo naukowe
Tytuł:
Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density.
Autorzy:
Langsetmo L; Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, Canada.
Poliquin S
Hanley DA
Prior JC
Barr S
Anastassiades T
Towheed T
Goltzman D
Kreiger N
Pokaż więcej
Corporate Authors:
CaMos Research Group
Źródło:
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2010 Jan 28; Vol. 11, pp. 20. Date of Electronic Publication: 2010 Jan 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Body Mass Index*
Bone Density/*physiology
Feeding Behavior/*physiology
Obesity/*epidemiology
Osteoporosis/*epidemiology
Adult ; Age Distribution ; Aged ; Canada/epidemiology ; Comorbidity ; Eating/physiology ; Female ; Femur Neck/diagnostic imaging ; Femur Neck/physiology ; Food ; Food Analysis ; Humans ; Male ; Middle Aged ; Obesity/metabolism ; Obesity/physiopathology ; Osteoporosis/metabolism ; Osteoporosis/physiopathology ; Radiography ; Sex Distribution ; Surveys and Questionnaires
Czasopismo naukowe
Tytuł:
Changes in body mass index in Canadians over a five-year period: results of a prospective, population-based study.
Autorzy:
Hopman WM; Clinical Research Centre, Kingston General Hospital and Department of Community Health and Epidemiology, Queen's University, Kingston, Ontario, Canada. />Leroux C
Berger C
Joseph L
Barr SI
Prior JC
Harrison M
Poliquin S
Towheed T
Anastassiades T
Goltzman D
Pokaż więcej
Corporate Authors:
CaMos Research Group
Źródło:
BMC public health [BMC Public Health] 2007 Jul 09; Vol. 7, pp. 150. Date of Electronic Publication: 2007 Jul 09.
Typ publikacji:
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Body Mass Index*
Obesity/*epidemiology
Osteoporosis/*epidemiology
Overweight/*physiology
Absorptiometry, Photon ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Canada/epidemiology ; Female ; Humans ; Life Style ; Longitudinal Studies ; Male ; Middle Aged ; Obesity/complications ; Osteoporosis/complications ; Osteoporosis/diagnosis ; Population Surveillance ; Regression Analysis ; Sex Factors ; Socioeconomic Factors
Czasopismo naukowe
Tytuł:
Mortality risk reduction differs according to bisphosphonate class: a 15-year observational study
Autorzy:
Bliuc, D.
Tran, T.
van Geel, T.
Adachi, J. D.
Berger, C.
van den Bergh, J.Aff5, Aff6
Eisman, J. A.Aff1, Aff7
Geusens, P.Aff2, Aff8
Goltzman, D.
Hanley, D. A.
Josse, R. G.
Kaiser, S.
Kovacs, C. S.
Langsetmo, L.
Prior, J. C.
Nguyen, T. V.Aff1, Aff16, Aff17
Center, J. R.Aff1, Aff16
For the CaMOS Research Group
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. 30(4):817-828
Czasopismo naukowe
Tytuł:
Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation
Autorzy:
Rizzoli, R.
Biver, E.
Bonjour, J.-P.
Coxam, V.
Goltzman, D.
Kanis, J. A.Aff4, Aff5
Lappe, J.
Rejnmark, L.
Sahni, S.
Weaver, C.
Weiler, H.
Reginster, J.-Y.
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. 29(9):1933-1948
Czasopismo naukowe
Tytuł:
Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus
Autorzy:
Khan, A. A.
Hanley, D. A.
Rizzoli, R.
Bollerslev, J.
Young, J.E.M
Rejnmark, L.
Thakker, R.
D’Amour, P.
Paul, T.
Van Uum, S.
Shrayyef, M. Zakaria
Goltzman, D.
Kaiser, S.
Cusano, N. E.
Bouillon, R.
Mosekilde, L.
Kung, A. W.
Rao, S. D.
Bhadada, S. K.
Clarke, B. L.
Liu, J.
Duh, Q.
Lewiecki, E. Michael
Bandeira, F.
Eastell, R.
Marcocci, C.
Silverberg, S. J.
Udelsman, R.
Davison, K. Shawn
Potts, Jr, J. T.
Brandi, M. L.
Bilezikian, J. P.
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. January 2017 28(1):1-19
Czasopismo naukowe
Tytuł:
Antidepressant use and 10-year incident fracture risk: the population-based Canadian Multicentre Osteoporosis Study (CaMoS)
Autorzy:
Moura, C.
Bernatsky, S.
Abrahamowicz, M.
Papaioannou, A.
Bessette, L.
Adachi, J.
Goltzman, D.
Prior, J.
Kreiger, N.
Towheed, T.
Leslie, W. D.
Kaiser, S.
Ioannidis, G.
Pickard, L.
Fraser, L.-A.
Rahme, E.
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. May 2014 25(5):1473-1481
Czasopismo naukowe
Tytuł:
Construction and validation of a simplified fracture risk assessment tool for Canadian women and men: results from the CaMos and Manitoba cohorts
Autorzy:
Leslie, W. D.
Berger, C.
Langsetmo, L.
Lix, L. M.
Adachi, J. D.
Hanley, D. A.
Ioannidis, G.
Josse, R. G.
Kovacs, C. S.
Towheed, T.
Kaiser, S.
Olszynski, W. P.
Prior, J. C.
Jamal, S.
Kreiger, N.
Goltzman, D.
Canadian Multicentre Osteoporosis Study (CaMos) Research Group
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. June 2011 22(6):1873-1883
Czasopismo naukowe
Tytuł:
Fragility fractures and the osteoporosis care gap in women: the Canadian Multicentre Osteoporosis Study
Autorzy:
Fraser, L.-A.
Ioannidis, G.
Adachi, J. D.
Pickard, L.
Kaiser, S. M.
Prior, J.
Brown, J. P.
Hanley, D. A.
Olszynski, W. P.
Anastassiades, T.
Jamal, S.
Josse, R.
Goltzman, D.
Papaioannou, A.
the CaMos Research Group
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. March 2011 22(3):789-796
Czasopismo naukowe
Tytuł:
Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos
Autorzy:
Fraser, L.-A.
Langsetmo, L.
Berger, C.
Ioannidis, G.
Goltzman, D.
Adachi, J. D.
Papaioannou, A.
Josse, R.
Kovacs, C. S.
Olszynski, W. P.
Towheed, T.
Hanley, D. A.
Kaiser, S. M.
Prior, J.
Jamal, S.
Kreiger, N.
Brown, J. P.
Johansson, H.
Oden, A.
McCloskey, E.
Kanis, J. A.
Leslie, W. D.
CaMos Research Group
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. March 2011 22(3):829-837
Czasopismo naukowe
Tytuł:
The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study
Autorzy:
Papaioannou, A.
Kennedy, C. C.
Ioannidis, G.
Sawka, A.
Hopman, W. M.
Pickard, L.
Brown, J. P.
Josse, R. G.
Kaiser, S.
Anastassiades, T.
Goltzman, D.
Papadimitropoulos, M.
Tenenhouse, A.
Prior, J. C.
Olszynski, W. P.
Adachi, J. D.
for the CaMos Study Group
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. May 2009 20(5):703-714
Czasopismo naukowe
Tytuł:
The osteoporosis care gap in men with fragility fractures: the Canadian Multicentre Osteoporosis Study
Autorzy:
Papaioannou, A.
Kennedy, C. C.
Ioannidis, G.
Gao, Y.
Sawka, A. M.
Goltzman, D.
Tenenhouse, A.
Pickard, L.
Olszynski, W. P.
Davison, K. S.
Kaiser, S.
Josse, R. G.
Kreiger, N.
Hanley, D. A.
Prior, J. C.
Brown, J. P.
Anastassiades, T.
Adachi, J. D.
CaMos Research Group
Pokaż więcej
Źródło:
Osteoporosis International: With other metabolic bone diseases. April 2008 19(4):581-587
Czasopismo naukowe
Tytuł:
Characteristics of hyperparathyroid states in the Canadian multicentre osteoporosis study (CaMos) and relationship to skeletal markers.
Autorzy:
Berger, C.
Almohareb, O.
Langsetmo, L.
Hanley, D.A.
Kovacs, C.S.
Josse, R.G.
Adachi, J.D.
Prior, J.C.
Towheed, T.
Davison, K.S.
Kaiser, S.M.
Brown, J.P.
Goltzman, D.
Pokaż więcej
Temat:
BONE density
PARATHYROID hormone
HYPERPARATHYROIDISM
OSTEOPOROSIS
BODY mass index
GLUCOCORTICOIDS
DIURETICS
Źródło:
Clinical Endocrinology; Mar2015, Vol. 82 Issue 3, p359-368, 10p, 4 Charts, 2 Graphs
Czasopismo naukowe
Tytuł:
Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study.
Autorzy:
Jamal, S. A.
Goltzman, D.
Hanley, D. A.
Papaioannou, A.
Prior, J. C.
Josse, R. G.
Pokaż więcej
Temat:
PHYSIOLOGICAL effects of nitrates
BONE density
OSTEOPOROSIS
LONGITUDINAL method
REGRESSION analysis
HIP joint abnormalities
SPINE abnormalities
Źródło:
Osteoporosis International; May2009, Vol. 20 Issue 5, p737-744, 8p, 2 Charts, 2 Graphs
Czasopismo naukowe
Tytuł:
The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women.
Autorzy:
Kanis, J.
Oden, A.
Johnell, O.
Johansson, H.
Laet, C.
Brown, J.
Burckhardt, P.
Cooper, C.
Christiansen, C.
Cummings, S.
Eisman, J.
Fujiwara, S.
Glüer, C.
Goltzman, D.
Hans, D.
Krieg, M.-A.
Croix, A.
McCloskey, E.
Mellstrom, D.
Melton, L.
Pokaż więcej
Temat:
DISEASE risk factors
OSTEOPOROSIS
RISK assessment
BONE fractures
BONE injuries
Źródło:
Osteoporosis International; Aug2007, Vol. 18 Issue 8, p1033-1046, 14p, 4 Charts, 2 Graphs
Czasopismo naukowe
    Wyświetlanie 1-53 z 53

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