- Tytuł:
-
Pyrroloquinoline quinone alleviates natural aging-related
osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation. - Autorzy:
- Źródło:
- Aging cell [Aging Cell] 2023 Sep; Vol. 22 (9), pp. e13912. Date of Electronic Publication: 2023 Jun 26.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Osteoporosis */drug therapyOsteoporosis */metabolism
Bone Resorption*/drug therapy
Mice ; Animals ; Antioxidants/metabolism ; PQQ Cofactor/pharmacology ; PQQ Cofactor/metabolism ; PQQ Cofactor/therapeutic use ; NF-E2-Related Factor 2/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; Up-Regulation ; Fibrillin-1/metabolism ; Molecular Docking Simulation ; Oxidative Stress ; Aging
Czasopismo naukowe