- Tytuł:
- The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis.
- Autorzy:
- Źródło:
- Scientific reports [Sci Rep] 2020 Jul 15; Vol. 10 (1), pp. 11636. Date of Electronic Publication: 2020 Jul 15.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Inflammation/*drug therapy
Kruppel-Like Transcription Factors/*chemistry
Pyrrolidinones/*chemistry
Solvents/*chemistry
Animals ; Anti-Inflammatory Agents/pharmacology ; Aorta/metabolism ; Apoptosis ; Atherosclerosis ; Cell Adhesion ; Cell Line ; DNA, Complementary/metabolism ; Endothelial Cells/drug effects ; Gene Expression Profiling ; Gene Library ; Human Umbilical Vein Endothelial Cells ; Humans ; Mice ; Mice, Knockout, ApoE ; Monocytes/cytology ; Monocytes/drug effects ; RNA, Small Interfering/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe