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    Wyświetlanie 1-11 z 11
    Tytuł:
    DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma.
    Autorzy:
    Ma RK; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
    Tsai PY; Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America.
    Farghli AR; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
    Shumway A; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
    Kanke M; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
    Gordan JD; Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, California, United States of America.
    Gujral TS; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.
    Vakili K; Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, United States of America.
    Nukaya M; Department of Surgery, Division of Surgical Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
    Noetzli L; Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America.
    Ronnekleiv-Kelly S; Department of Surgery, Division of Surgical Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
    Broom W; Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America.
    Barrow J; Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America.
    Sethupathy P; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
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    Źródło:
    PLoS genetics [PLoS Genet] 2024 Mar 21; Vol. 20 (3), pp. e1011216. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Carcinoma, Hepatocellular*/genetics
    Carcinoma, Hepatocellular*/pathology
    Liver Neoplasms*/metabolism
    RNA, Long Noncoding*/genetics
    RNA, Long Noncoding*/metabolism
    Adolescent ; Young Adult ; Humans ; HSP40 Heat-Shock Proteins/genetics ; HSP40 Heat-Shock Proteins/metabolism ; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits/genetics
    SCR Disease Name:
    Fibrolamellar hepatocellular carcinoma
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A protein interaction landscape of breast cancer.
    Autorzy:
    Kim M; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Park J; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, University of California, San Diego, CA, USA.
    Bouhaddou M; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Kim K; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Rojc A; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Modak M; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Soucheray M; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    McGregor MJ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    O'Leary P; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
    Wolf D; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
    Stevenson E; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Foo TK; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
    Mitchell D; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.; Division of Hematology/Oncology, University of California, San Francisco, CA, USA.
    Herrington KA; Department of Biochemistry and Biophysics, Center for Advanced Light Microscopy, University of California, San Francisco, CA, USA.
    Muñoz DP; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
    Tutuncuoglu B; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Chen KH; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Zheng F; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, University of California, San Diego, CA, USA.
    Kreisberg JF; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, University of California, San Diego, CA, USA.
    Diolaiti ME; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
    Gordan JD; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.; Division of Hematology/Oncology, University of California, San Francisco, CA, USA.
    Coppé JP; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
    Swaney DL; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
    Xia B; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
    van 't Veer L; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
    Ashworth A; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
    Ideker T; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.; Department of Medicine, University of California, San Diego, CA, USA.; Department of Bioengineering, University of California, San Diego, CA, USA.
    Krogan NJ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; The J. David Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; The Cancer Cell Map Initiative, San Francisco and La Jolla, CA, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2021 Oct; Vol. 374 (6563), pp. eabf3066. Date of Electronic Publication: 2021 Oct 01.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Protein Interaction Maps*
    Breast Neoplasms/*metabolism
    Neoplasm Proteins/*metabolism
    Breast Neoplasms/genetics ; Cell Line, Tumor ; Female ; Humans ; Mass Spectrometry ; Mutation ; Neoplasm Proteins/genetics ; Neoplasm Proteins/isolation & purification ; Tandem Affinity Purification
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Tumor hepatitis B virus RNA identifies a clinically and molecularly distinct subset of hepatocellular carcinoma.
    Autorzy:
    Lim HC; Division of Hematology and Oncology, University of California, San Francisco, San Francisco, California, United States of America.
    Gordan JD; Division of Hematology and Oncology, University of California, San Francisco, San Francisco, California, United States of America.
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    Źródło:
    PLoS computational biology [PLoS Comput Biol] 2021 Feb 09; Vol. 17 (2), pp. e1008699. Date of Electronic Publication: 2021 Feb 09 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    RNA, Viral*
    Carcinoma, Hepatocellular/*genetics
    Hepatitis B virus/*genetics
    Liver Neoplasms/*genetics
    Adult ; Aged ; Biomarkers, Tumor ; Cell Line, Tumor ; Computational Biology ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; DNA Repair ; Female ; Humans ; Kelch-Like ECH-Associated Protein 1/genetics ; Male ; Middle Aged ; Mutation ; Phenotype ; Principal Component Analysis ; Proportional Hazards Models ; Tumor Suppressor Protein p53/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.
    Autorzy:
    Evason KJ; Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America; Department of Biochemistry and Biophysics, Programs in Developmental and Stem Cell Biology, Genetics and Human Genetics, Diabetes Center, Institute for Regeneration Medicine and the Liver Center, University of California, San Francisco, San Francisco, California, United States of America.
    Francisco MT; Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America; Department of Cell & Tissue Biology, University of California, San Francisco, San Francisco, California, United States of America.
    Juric V; The George Williams Hooper Research Foundation, University of California, San Francisco, San Francisco, California, United States of America.
    Balakrishnan S; Department of Cell & Tissue Biology, University of California, San Francisco, San Francisco, California, United States of America.
    Lopez Pazmino Mdel P; Department of Biochemistry and Biophysics, Programs in Developmental and Stem Cell Biology, Genetics and Human Genetics, Diabetes Center, Institute for Regeneration Medicine and the Liver Center, University of California, San Francisco, San Francisco, California, United States of America.
    Gordan JD; Department of Medicine, University of California, San Francisco, San Francisco, California, United States of America.
    Kakar S; Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America.
    Spitsbergen J; Department of Microbiology, Oregon State University, Corvallis, Oregon, United States of America.
    Goga A; Department of Cell & Tissue Biology, University of California, San Francisco, San Francisco, California, United States of America; Department of Medicine, University of California, San Francisco, San Francisco, California, United States of America.
    Stainier DY; Department of Biochemistry and Biophysics, Programs in Developmental and Stem Cell Biology, Genetics and Human Genetics, Diabetes Center, Institute for Regeneration Medicine and the Liver Center, University of California, San Francisco, San Francisco, California, United States of America.
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    Źródło:
    PLoS genetics [PLoS Genet] 2015 Jul 02; Vol. 11 (7), pp. e1005305. Date of Electronic Publication: 2015 Jul 02 (Print Publication: 2015).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Amitriptyline/*therapeutic use
    Antidepressive Agents, Tricyclic/*therapeutic use
    Carcinoma, Hepatocellular/*drug therapy
    Liver Neoplasms/*drug therapy
    beta Catenin/*metabolism
    Animals ; Animals, Genetically Modified ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Transformation, Neoplastic/drug effects ; Disease Models, Animal ; Gene Expression Regulation, Neoplastic ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Humans ; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors ; JNK Mitogen-Activated Protein Kinases/metabolism ; Liver/pathology ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; MAP Kinase Signaling System/drug effects ; Mesothelin ; Mice ; Selective Serotonin Reuptake Inhibitors/therapeutic use ; Xenopus laevis ; Zebrafish ; beta Catenin/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma.
    Autorzy:
    Wright TM; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA.
    Brannon AR
    Gordan JD
    Mikels AJ
    Mitchell C
    Chen S
    Espinosa I
    van de Rijn M
    Pruthi R
    Wallen E
    Edwards L
    Nusse R
    Rathmell WK
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    Źródło:
    Oncogene [Oncogene] 2009 Jul 09; Vol. 28 (27), pp. 2513-23. Date of Electronic Publication: 2009 May 18.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cell Proliferation*
    Carcinoma, Renal Cell/*pathology
    Kidney Neoplasms/*pathology
    Receptors, Cell Surface/*metabolism
    Animals ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/metabolism ; Cell Line, Tumor ; Cell Movement ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Immunoblotting ; Immunohistochemistry ; Kidney Neoplasms/genetics ; Kidney Neoplasms/metabolism ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 2/metabolism ; Mice ; Mice, Nude ; Neoplasm Transplantation ; Neoplasms, Experimental/genetics ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Oligonucleotide Array Sequence Analysis ; Phosphorylation ; RNA Interference ; Receptor Protein-Tyrosine Kinases/genetics ; Receptor Protein-Tyrosine Kinases/metabolism ; Receptor Tyrosine Kinase-like Orphan Receptors ; Receptors, Cell Surface/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Transplantation, Heterologous ; Tumor Burden ; Twist-Related Protein 1/genetics ; Twist-Related Protein 1/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-11 z 11

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