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Tytuł :
Determination of cellularly processed HLA-A2402-restricted novel CTL epitopes derived from two cancer germ line genes, MAGE-A4 and SAGE.
Autorzy :
Miyahara Y; Second Department of Internal Medicine and Department of Otorhinolaryngology, Mie University School of Medicine, Mie, Japan.
Naota H
Wang L
Hiasa A
Goto M
Watanabe M
Kitano S
Okumura S
Takemitsu T
Yuta A
Majima Y
Lemonnier FA
Boon T
Shiku H
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Źródło :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2005 Aug 01; Vol. 11 (15), pp. 5581-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Neoplasm/*chemistry
HLA-A Antigens/*metabolism
Neoplasm Proteins/*chemistry
Neoplasms/*genetics
T-Lymphocytes, Cytotoxic/*immunology
Animals ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cancer Vaccines/metabolism ; Cell Line, Tumor ; DNA/metabolism ; Electroporation ; Epitopes/chemistry ; Flow Cytometry ; HLA-A24 Antigen ; Humans ; Leukocytes, Mononuclear/cytology ; Leukocytes, Mononuclear/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Peptides/chemistry ; Plasmids/metabolism ; RNA, Messenger/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Mast cell chymase induces expression of chemokines for neutrophils in eosinophilic EoL-1 cells and mouse peritonitis eosinophils.
Autorzy :
Terakawa M; Daiichi Asubio Pharma Co. Limited, Biomedical Research Laboratories, 1-1-1 Wakayamadai, Shimamoto-cho, Mishima-gun, Osaka 618-8513, Japan.
Tomimori Y
Goto M
Fukuda Y
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2006 May 24; Vol. 538 (1-3), pp. 175-81. Date of Electronic Publication: 2006 May 09.
Typ publikacji :
Journal Article
MeSH Terms :
Chemokines/*metabolism
Eosinophils/*drug effects
Neutrophils/*drug effects
Peritonitis/*pathology
Serine Endopeptidases/*pharmacology
Animals ; Butadienes/pharmacology ; Cell Line, Tumor ; Chemokine CXCL2 ; Chemokines/genetics ; Chymases ; Cytokines/genetics ; Cytokines/metabolism ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/pharmacology ; Eosinophils/metabolism ; Eosinophils/pathology ; Gene Expression/drug effects ; Humans ; Imidazoles/pharmacology ; Interleukin-8/genetics ; Interleukin-8/metabolism ; Mice ; Mice, Inbred BALB C ; Mitogen-Activated Protein Kinases/antagonists & inhibitors ; Neutrophils/metabolism ; Neutrophils/pathology ; Nitriles/pharmacology ; Peritonitis/genetics ; Peritonitis/metabolism ; Pertussis Toxin/pharmacology ; Pyridines/pharmacology ; Quinazolines/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Investigation and characterization of rat bipedal walking models established by a training program.
Autorzy :
Wada N; Laboratory of System Physiology, School of Veterinary Medicine, Yamaguchi University, Yamaguchi City, 753-8515, Japan. />Toba Y
Iwamoto W
Goto M
Miyata H
Mori F
Morita F
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Źródło :
Brain research [Brain Res] 2008 Dec 03; Vol. 1243, pp. 70-7. Date of Electronic Publication: 2008 Sep 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Forelimb/*physiology
Hindlimb/*physiology
Locomotion/*physiology
Muscle, Skeletal/*physiology
Physical Conditioning, Animal/*methods
Walking/*physiology
Adaptation, Physiological/physiology ; Animals ; Animals, Newborn ; Biomechanical Phenomena/physiology ; Central Nervous System/growth & development ; Electromyography ; Female ; Gait/physiology ; Joints/physiology ; Male ; Models, Biological ; Muscle Contraction/physiology ; Neuronal Plasticity/physiology ; Postural Balance/physiology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Murine NKT cells produce Th17 cytokine interleukin-22.
Autorzy :
Goto M; Biomedical Research Laboratories, Asubio Pharma Co., Limited, 1-1-1 Wakayamadai, Shimamoto-cho, Mishima-gun, Osaka 618-8503, Japan.
Murakawa M
Kadoshima-Yamaoka K
Tanaka Y
Nagahira K
Fukuda Y
Nishimura T
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Źródło :
Cellular immunology [Cell Immunol] 2009; Vol. 254 (2), pp. 81-4. Date of Electronic Publication: 2008 Nov 17.
Typ publikacji :
Journal Article
MeSH Terms :
Interleukin-17/*immunology
Interleukins/*biosynthesis
Interleukins/*immunology
Natural Killer T-Cells/*immunology
T-Lymphocytes, Helper-Inducer/*immunology
Animals ; Cells, Cultured ; Female ; Interleukin-6/pharmacology ; Mice ; Mice, Inbred C57BL ; Natural Killer T-Cells/drug effects ; Natural Killer T-Cells/metabolism ; Spleen/immunology ; Transforming Growth Factor beta/pharmacology
Czasopismo naukowe
Tytuł :
Phosphodiesterase 7A inhibitor ASB16165 suppresses proliferation and cytokine production of NKT cells.
Autorzy :
Goto M; Biomedical Research Laboratories, Asubio Pharma Co., Limited, Osaka, Japan.
Murakawa M
Kadoshima-Yamaoka K
Tanaka Y
Inoue H
Murafuji H
Hayashi Y
Miura K
Nakatsuka T
Nagahira K
Chamoto K
Fukuda Y
Nishimura T
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Źródło :
Cellular immunology [Cell Immunol] 2009; Vol. 258 (2), pp. 147-51. Date of Electronic Publication: 2009 May 27.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclic Nucleotide Phosphodiesterases, Type 7/*metabolism
Cytokines/*antagonists & inhibitors
Enzyme Inhibitors/*pharmacology
Natural Killer T-Cells/*drug effects
Pyrazoles/*pharmacology
Thiophenes/*pharmacology
Animals ; Cell Proliferation ; Cyclic AMP/metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 7/antagonists & inhibitors ; Cytokines/biosynthesis ; Female ; Mice ; Mice, Inbred C57BL ; Natural Killer T-Cells/immunology
Czasopismo naukowe
Tytuł :
Characteristics of H- and M-waves recorded from rat forelimbs.
Autorzy :
Hosoido T; Osaka Veterinary Referral Center, Osaka City 537-0025, Japan.
Motoyama S
Goto M
Mori F
Tajima T
Hirata H
Wada N
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Źródło :
Neuroscience letters [Neurosci Lett] 2009 Feb 06; Vol. 450 (3), pp. 239-41. Date of Electronic Publication: 2008 Nov 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Forelimb/*physiology
H-Reflex/*physiology
Hindlimb/*physiology
Muscle, Skeletal/*physiology
Nerve Net/*physiology
Spinal Cord/*physiology
Action Potentials/physiology ; Animals ; Efferent Pathways/physiology ; Electric Stimulation ; Female ; Forelimb/innervation ; Gait/physiology ; Hindlimb/innervation ; Locomotion/physiology ; Male ; Motor Neurons/physiology ; Muscle Contraction/physiology ; Muscle, Skeletal/innervation ; Neural Pathways/physiology ; Peripheral Nerves/physiology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
ASB16165, a novel inhibitor for phosphodiesterase 7A (PDE7A), suppresses IL-12-induced IFN-γ production by mouse activated T lymphocytes
Autorzy :
Kadoshima-Yamaoka, Kumiko
Murakawa, Masao
Goto, Megumi
Tanaka, Yoshitaka
Inoue, Hidekazu
Murafuji, Hidenobu
Nagahira, Asako
Hayashi, Yasuhiro
Nagahira, Kazuhiro
Miura, Kenju
Nakatsuka, Takashi
Chamoto, Kenji
Fukuda, Yoshiaki
Nishimura, Takashi
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Źródło :
Immunology Letters. Feb2009, Vol. 122 Issue 2, p193-197. 5p.
Czasopismo naukowe
Tytuł :
ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-alpha level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice.
Autorzy :
Kadoshima-Yamaoka K; Biomedical Research Laboratories, Asubio Pharma Co Limited, Osaka, Japan.
Goto M
Murakawa M
Yoshioka R
Tanaka Y
Inoue H
Murafuji H
Kanki S
Hayashi Y
Nagahira K
Ogata A
Nakatsuka T
Fukuda Y
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2009 Jun 24; Vol. 613 (1-3), pp. 163-6. Date of Electronic Publication: 2009 Apr 18.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclic Nucleotide Phosphodiesterases, Type 7/*antagonists & inhibitors
Edema/*drug therapy
Inflammation/*drug therapy
Pyrazoles/*pharmacology
Skin/*drug effects
Tetradecanoylphorbol Acetate/*toxicity
Thiophenes/*pharmacology
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Edema/metabolism ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Epidermis/drug effects ; Epidermis/metabolism ; Female ; Gene Expression Regulation/drug effects ; Humans ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation/pathology ; Keratinocytes/drug effects ; Keratinocytes/metabolism ; Mice ; Mice, Inbred BALB C ; Pyrazoles/therapeutic use ; Skin/metabolism ; Skin/pathology ; Thiophenes/therapeutic use ; Tumor Necrosis Factor-alpha/biosynthesis
Czasopismo naukowe
Tytuł :
ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-α level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice
Autorzy :
Kadoshima-Yamaoka, Kumiko
Goto, Megumi
Murakawa, Masao
Yoshioka, Ryosuke
Tanaka, Yoshitaka
Inoue, Hidekazu
Murafuji, Hidenobu
Kanki, Satomi
Hayashi, Yasuhiro
Nagahira, Kazuhiro
Ogata, Atsuto
Nakatsuka, Takashi
Fukuda, Yoshiaki
Pokaż więcej
Źródło :
European Journal of Pharmacology. Jun2009, Vol. 613 Issue 1-3, p163-166. 4p.
Czasopismo naukowe
Tytuł :
The polysynaptic pathways from the low threshold cutaneous afferents of the trunk to motoneurons innervating hindlimb muscles in the spinal cat.
Autorzy :
Wada Y; The United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan. />Goto M
Sano Y
Hosoido T
Wada N
Pokaż więcej
Źródło :
The Journal of veterinary medical science [J Vet Med Sci] 2010 Jan; Vol. 72 (1), pp. 73-6. Date of Electronic Publication: 2009 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Cats/*physiology
Motor Neurons/*physiology
Muscle, Skeletal/*innervation
Neural Pathways/*physiology
Spinal Cord/*physiology
Afferent Pathways ; Animals ; Electrophysiology ; Excitatory Postsynaptic Potentials ; Female ; Hindlimb/physiology ; Male ; Neural Inhibition
Czasopismo naukowe

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