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Tytuł:
Clinical Features of Gastric Signet Ring Cell Cancer: Results from a Systematic Review and Meta-Analysis.
Autorzy:
Dal Cero M; General and Upper GI Surgery Division, Department of Surgery, University of Verona, Borgo Trento Hospital, Piazzale Stefani 1, 37124 Verona, Italy.; Section of Gastrointestinal Surgery, Hospital Universitario del Mar, Hospital del Mar Medical Research Institute (IMIM), Department of Surgery, Universitat Autònoma de Barcelona, 08003 Barcelona, Spain.
Bencivenga M; General and Upper GI Surgery Division, Department of Surgery, University of Verona, Borgo Trento Hospital, Piazzale Stefani 1, 37124 Verona, Italy.
Liu DHW; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.; Institute of Clinical Pathology and Molecular Pathology, Kepler University Hospital and Johannes Kepler University, 4021 Linz, Austria.
Sacco M; General and Upper GI Surgery Division, Department of Surgery, University of Verona, Borgo Trento Hospital, Piazzale Stefani 1, 37124 Verona, Italy.
Alloggio M; General and Upper GI Surgery Division, Department of Surgery, University of Verona, Borgo Trento Hospital, Piazzale Stefani 1, 37124 Verona, Italy.
Kerckhoffs KGP; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.; Department of Pathology, VieCuri Medical Centre, 5912 BL Venlo, The Netherlands.
Filippini F; General and Upper GI Surgery Division, Department of Surgery, University of Verona, Borgo Trento Hospital, Piazzale Stefani 1, 37124 Verona, Italy.
Saragoni L; Pathology Unit, Morgagni-Pierantoni Hospital, 47100 Forlì, Italy.
Iglesias M; Department of Pathology, Hospital Universitario del Mar, Hospital del Mar Medical Research Institute (IMIM), 08003 Barcelona, Spain.
Tomezzoli A; Department of Pathology, Verona University Hospital, 37134 Verona, Italy.
Carneiro F; Department of Pathology, Medical Faculty of the University of Porto/Centro Hospitalar Universitário São João and Ipatimup/i3S, 4200-319 Porto, Portugal.
Grabsch HI; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds LS2 9JT, UK.
Verlato G; Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, 37126 Verona, Italy.
Torroni L; Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, 37126 Verona, Italy.
Piessen G; Department of Digestive and Oncological Surgery, Lille University Hospital, 59000 Lille, France.
Pera M; Section of Gastrointestinal Surgery, Hospital Universitario del Mar, Hospital del Mar Medical Research Institute (IMIM), Department of Surgery, Universitat Autònoma de Barcelona, 08003 Barcelona, Spain.
de Manzoni G; General and Upper GI Surgery Division, Department of Surgery, University of Verona, Borgo Trento Hospital, Piazzale Stefani 1, 37124 Verona, Italy.
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Źródło:
Cancers [Cancers (Basel)] 2023 Oct 28; Vol. 15 (21). Date of Electronic Publication: 2023 Oct 28.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Automated detection and delineation of lymph nodes in haematoxylin & eosin stained digitised slides.
Autorzy:
Beuque M; Department of Precision Medicine, GROW School for Oncology and Reproduction, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, the Netherlands.
Magee DR; School of Computing, University of Leeds, LS2 9JT Leeds, United Kingdom.; HeteroGenius Limited, Leeds, United Kingdom.
Chatterjee A; Department of Precision Medicine, GROW School for Oncology and Reproduction, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, the Netherlands.
Woodruff HC; Department of Precision Medicine, GROW School for Oncology and Reproduction, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, the Netherlands.; Department of Radiology and Nuclear Medicine, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, P. Debyelaan, 25 6229 HX Maastricht, The Netherlands.
Langley RE; MRC Clinical Trials Unit at University College London, 90 High Holborn, WC1V 6LJ London, United Kingdom.
Allum W; Department of Surgery, Royal Marsden Hospital, The Royal Marsden Fulham Road, SW3 6JJ London, United Kingdom.
Nankivell MG; MRC Clinical Trials Unit at University College London, 90 High Holborn, WC1V 6LJ London, United Kingdom.
Cunningham D; Department of Medicine, The Royal Marsden NHS Trust, The Royal Marsden Fulham Road, SW3 6JJ London, United Kingdom.
Lambin P; Department of Precision Medicine, GROW School for Oncology and Reproduction, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, the Netherlands.; Department of Radiology and Nuclear Medicine, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, P. Debyelaan, 25 6229 HX Maastricht, The Netherlands.
Grabsch HI; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, P. Debyelaan, 25 6229 HX Maastricht, The Netherlands.; Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, LS2 9JT Leeds, United Kingdom.
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Źródło:
Journal of pathology informatics [J Pathol Inform] 2023 Jan 25; Vol. 14, pp. 100192. Date of Electronic Publication: 2023 Jan 25 (Print Publication: 2023).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Association between mutational subgroups, Warburg-subtypes, and survival in patients with colorectal cancer.
Autorzy:
Offermans K; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Jenniskens JCA; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Simons CCJM; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Samarska I; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Fazzi GE; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
van der Meer JRM; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Smits KM; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Schouten LJ; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Weijenberg MP; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Grabsch HI; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
van den Brandt PA; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.; Department of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, The Netherlands.
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Źródło:
Cancer medicine [Cancer Med] 2023 Jan; Vol. 12 (2), pp. 1137-1156. Date of Electronic Publication: 2022 Jul 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins B-raf*/genetics
Colorectal Neoplasms*/genetics
Humans ; Prospective Studies ; Cohort Studies ; Proto-Oncogene Proteins p21(ras)/genetics ; Prognosis ; Mutation ; Class I Phosphatidylinositol 3-Kinases/genetics ; DNA Mutational Analysis
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Data Set for Reporting Carcinoma of the Stomach in Gastrectomy.
Autorzy:
Shi C; From the Department of Pathology, Duke University School of Medicine, Durham, North Carolina (Shi).
Badgwell BD; From the Division of Surgery, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston (Badgwell).
Grabsch HI; From the Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands (Grabsch).; From the Division of Pathology & Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom (Grabsch).
Gibson MK; From the Division of Hematology and Oncology, Vanderbilt University Medical Center, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee (Gibson).
Hong SM; From the Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea (Hong).
Kumarasinghe P; From PathWest Laboratory Medicine, PathWest QEII Medical Center, Perth, Australia (Kumarasinghe).
Lam AK; From Pathology, School of Medicine, Gold Coast Campus, Griffith University, Gold Coast, Australia (Lam).; From Pathology Queensland, Gold Coast University Hospital, Southport, Australia (Lam).; From Faculty of Medicine, The University of Queensland, Herston, Australia (Lam).
Lauwers G; From the Department of Pathology, Moffitt Cancer Center, Tampa, Florida (Lauwers).
O'Donovan M; From the Histopathology Department, Cambridge University Hospitals NHS Foundation Trust Addenbrookes Hospital, Cambridge, United Kingdom (O'Donovan).
van der Post RS; From the Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands (van der Post and Nagtegaal).
Tang L; From the Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, New York, (Tang).
Ushiku T; From the Department of Pathology and Diagnostic Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan (Ushiku).
Vieth M; From the Institute of Pathology, Friedrich-Alexander University Erlangen-Nuremberg, Klinikum Bayreuth, Germany (Vieth).
Selinger CI; From the Royal College of Pathologists of Australasia, Sydney, Australia (Selinger).
Webster F; From the International Collaboration on Cancer Reporting, Sydney, Australia (Webster).
Nagtegaal ID; From the Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands (van der Post and Nagtegaal).
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2022 Sep 01; Vol. 146 (9), pp. 1072-1083.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma*/pathology
Pathology, Clinical*
Stomach Neoplasms*/surgery
Gastrectomy ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Gastric cancer biomarker analysis in patients treated with different adjuvant chemotherapy regimens within SAMIT, a phase III randomized controlled trial.
Autorzy:
Oshima T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, Yokohama, Kanagawa, 241-8515, Japan.
Tsuburaya A; Department of Surgery, Ozawa Hospital, 1-1-17, Honcho, Odawara, Kanagawa, 250-0012, Japan. .
Yoshida K; Department of Surgical Oncology, Gifu University Graduate School of Medicine, 1-1 Yanagito, Gifu, Gifu, 501-1194, Japan.
Yoshikawa T; Department of Gastric Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Miyagi Y; Kanagawa Cancer Center Research Institute, 2-3-2 Nakao, Asahi-ku, Yokohama, Kanagawa, 241-8515, Japan.
Rino Y; Department of Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.
Masuda M; Department of Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.
Guan J; Department of Clinical Biostatistics, Graduate School of Medicine, Kyoto University, Yoshida Konoe-cho Sakyo-ku, Kyoto, Kyoto, 606-8501, Japan.
Tan P; Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore, 117599, Singapore.
Grabsch HI; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Sakamoto J; Tokai Central Hospital, 4-6-2 Sohara Higashijimacho, Kakamigahara, Gifu, 504-8601, Japan.
Tanaka S; Department of Clinical Biostatistics, Graduate School of Medicine, Kyoto University, Yoshida Konoe-cho Sakyo-ku, Kyoto, Kyoto, 606-8501, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 May 20; Vol. 12 (1), pp. 8509. Date of Electronic Publication: 2022 May 20.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Stomach Neoplasms*/drug therapy
Stomach Neoplasms*/genetics
Stomach Neoplasms*/surgery
Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Biomarkers, Tumor/genetics ; Chemotherapy, Adjuvant/adverse effects ; Disease-Free Survival ; Humans ; Neoplasm Recurrence, Local/drug therapy ; Paclitaxel/therapeutic use ; Pyrimidines/therapeutic use ; RNA
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Histopathological Features in Colonic Biopsies at Diagnosis Predict Long-term Disease Course in Patients with Crohn's Disease.
Autorzy:
Rezazadeh Ardabili A; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University Medical Center+, Maastricht, The Netherlands.; School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
Goudkade D; Department of Pathology, Zuyderland Medical Centre, Geleen, The Netherlands.
Wintjens D; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University Medical Center+, Maastricht, The Netherlands.; School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
Romberg-Camps M; Department of Gastroenterology, Geriatrics, Internal and Intensive Care Medicine, Zuyderland Medical Centre, Sittard-Geleen, The Netherlands.
Winkens B; Department of Methodology and Statistics, Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
Pierik M; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University Medical Center+, Maastricht, The Netherlands.; School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
Grabsch HI; Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, The Netherlands.; Division of Pathology & Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Jonkers D; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University Medical Center+, Maastricht, The Netherlands.; School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
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Źródło:
Journal of Crohn's & colitis [J Crohns Colitis] 2021 Nov 08; Vol. 15 (11), pp. 1885-1897.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Biopsy/*methods
Colon/*pathology
Crohn Disease/*diagnosis
Adult ; Cohort Studies ; Colon/physiopathology ; Crohn Disease/epidemiology ; Crohn Disease/physiopathology ; Disease Progression ; Humans ; Logistic Models ; Male ; Middle Aged ; ROC Curve ; Retrospective Studies ; Severity of Illness Index
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Validation of the 'Inflammatory Bowel Disease-Distribution, Chronicity, Activity [IBD-DCA] Score' for Ulcerative Colitis and Crohn´s Disease.
Autorzy:
Lang-Schwarz C; Institute of Pathology, Klinikum Bayreuth GmbH, Bayreuth, Germany.
Angeloni M; Institute of Pathology, Friedrich-Alexander-University, Erlangen, Germany.
Agaimy A; Institute of Pathology, Friedrich-Alexander-University, Erlangen, Germany.
Atreya R; Department of Medicine & Deutsches Zentrum Immuntherapie DZI, University Hospital, Friedrich-Alexander-University, Erlangen, Germany.; Transregio 241 IBDome Consortium, Erlangen, Berlin, Germany.
Becker C; Department of Medicine & Deutsches Zentrum Immuntherapie DZI, University Hospital, Friedrich-Alexander-University, Erlangen, Germany.; Transregio 241 IBDome Consortium, Erlangen, Berlin, Germany.
Dregelies T; Institute of Pathology, Klinikum Bayreuth GmbH, Bayreuth, Germany.
Danese S; Department of Gastroenterology, Humanitas Research Hospital, Rozzano, Milan, Italy.
Fléjou JF; Pathology Department, Saint-Antoine Hospital, Pierre et Marie Curie University, Paris, France.
Gaßler N; Institute for Legal Medicine, Section Pathology, University Hospital, Jena, Germany.
Grabsch HI; Department of Pathology, School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Hartmann A; Institute of Pathology, Friedrich-Alexander-University, Erlangen, Germany.
Kamarádová K; Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Králové, Czech Republic.
Kühl AA; Charité - Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Transregio 241 IBDome Consortium, Erlangen, Berlin, Germany.
Lauwers GY; Department of Pathology, Moffitt Cancer Center, Tampa, FL, USA.
Lugli A; Institute of Pathology, University of Bern, Bern, Switzerland.
Nagtegaal I; Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Neurath MF; Department of Medicine & Deutsches Zentrum Immuntherapie DZI, University Hospital, Friedrich-Alexander-University, Erlangen, Germany.; Transregio 241 IBDome Consortium, Erlangen, Berlin, Germany.
Oberhuber G; Institute of Pathology, Tirol Kliniken, Innsbruck, Austria.; Institute of Pathology, Patho im Zentrum, St. Pölten, Austria.
Peyrin-Biroulet L; Department of Gastroenterology, Nancy University Hospital, Lorraine University, Vandoeuvre, France.
Rath T; Department of Medicine & Deutsches Zentrum Immuntherapie DZI, University Hospital, Friedrich-Alexander-University, Erlangen, Germany.
Riddell R; Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
Rubio CA; Department of Pathology, Karolinska Institute and University Hospital, Stockholm, Sweden.
Sheahan K; Department of Pathology & Centre for Colorectal Disease, St Vincent´s University Hospital and University College, Dublin, Ireland.
Siegmund B; Medical Department [Gastroenterology, Infectiology, Rheumatology], Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Transregio 241 IBDome Consortium, Erlangen, Berlin, Germany.
Tilg H; Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University Innsbruck, Innsbruck, Austria.
Villanacci V; Department of Pathology, Spedali Civili Brescia, Brescia, Italy.
Westerhoff M; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Ferrazzi F; Institute of Pathology, Friedrich-Alexander-University, Erlangen, Germany.; Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.
Vieth M; Institute of Pathology, Klinikum Bayreuth GmbH, Bayreuth, Germany.; Institute of Pathology, Friedrich-Alexander-University, Erlangen, Germany.
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Źródło:
Journal of Crohn's & colitis [J Crohns Colitis] 2021 Oct 07; Vol. 15 (10), pp. 1621-1630.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Severity of Illness Index*
Colitis, Ulcerative/*pathology
Crohn Disease/*pathology
Biopsy ; Humans ; Intestinal Mucosa/pathology ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A national study to assess outcomes of definitive chemoradiation regimens in proximal esophageal cancer.
Autorzy:
de Vos-Geelen J; Department of Internal Medicine, Division of Medical Oncology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Hoebers FJP; Department of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Geurts SME; Department of Internal Medicine, Division of Medical Oncology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Hoeben A; Department of Internal Medicine, Division of Medical Oncology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
de Greef BTA; Department of Clinical Epidemiology and Medical Technology Assessment (KEMTA), Maastricht University Medical Center, Maastricht, The Netherlands.
Voncken FEM; Department of Radiation Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
Bogers JHA; Radiotherapiegroep Arnhem, Arnhem, The Netherlands.
Braam PM; Department of Radiotherapy, Nijmegen, The Netherlands.
Muijs CKT; Department of Radiotherapy, University Medical Center Groningen, Groningen, The Netherlands.
de Jong MA; Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Kasperts N; Department of Radiotherapy, University Medical Center Utrecht, Utrecht, The Netherlands.
Rozema T; Insituut Verbeeten, Tilburg, The Netherlands.
Jeene PM; Department of Radiotherapy, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Radiotherapiegroep, Deventer, The Netherlands.
Blom GJ; Department of Radiation Oncology, Amsterdam University Medical Centers, VU University, Amsterdam, The Netherlands.
van Dieren JM; Department of Gastrointestinal Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
Hulshof MCCM; Department of Radiotherapy, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
van Laarhoven HWM; Department of Medical Oncology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Grabsch HI; Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.; Pathology & Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Lemmens VEPP; Department of Research, Netherlands Comprehensive Cancer Organization (IKNL), The Netherlands.; Department of Public Health, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.
Tjan-Heijnen VCG; Department of Internal Medicine, Division of Medical Oncology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Nieuwenhuijzen GAP; Department of Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
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Źródło:
Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2020 Aug; Vol. 59 (8), pp. 895-903. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji:
Journal Article; Multicenter Study; Observational Study
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Carcinoma, Squamous Cell/*therapy
Chemoradiotherapy/*methods
Esophageal Neoplasms/*therapy
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Carboplatin/administration & dosage ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/pathology ; Chemoradiotherapy/adverse effects ; Cisplatin/administration & dosage ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Netherlands ; Paclitaxel/administration & dosage ; Propensity Score ; Proportional Hazards Models ; Radiotherapy Dosage ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
EORTC-1203-GITCG - the "INNOVATION"-trial: Effect of chemotherapy alone versus chemotherapy plus trastuzumab, versus chemotherapy plus trastuzumab plus pertuzumab, in the perioperative treatment of HER2 positive, gastric and gastroesophageal junction adenocarcinoma on pathologic response rate: a randomized phase II-intergroup trial of the EORTC-Gastrointestinal Tract Cancer Group, Korean Cancer Study Group and Dutch Upper GI-Cancer group.
Autorzy:
Wagner AD; Department of Oncology, Lausanne University Hospital and University of Lausanne, Bugnon 46, 1011, Lausanne, Switzerland. .
Grabsch HI; Department of Pathology and GROW School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, Netherlands.; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Mauer M; EORTC Headquarters, Avenue E. Mounier 83, 1200, Bruxelles, Belgium.
Marreaud S; EORTC Headquarters, Avenue E. Mounier 83, 1200, Bruxelles, Belgium.
Caballero C; EORTC Headquarters, Avenue E. Mounier 83, 1200, Bruxelles, Belgium.
Thuss-Patience P; Department of Hematology, Medical Oncology and Tumor Immunology, Augustenburger Platz 1, Charité Universitätsmedizin Berlin, 13353, Berlin, Germany.
Mueller L; OnkologieUnterEms, 26789, Leer, Germany.
Elme A; North Estonian Regional Hospital Cancer Center, Hiiu 44, 11619, Tallinn, Estonia.
Moehler MH; University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.; Department of Internal Medicine III, SLK-Kliniken Heilbronn GmbH, Am Gesundbrunnen 20-26, 74078, Heilbronn, Germany.
Martens U; Department of Internal Medicine III, SLK-Kliniken Heilbronn GmbH, Am Gesundbrunnen 20-26, 74078, Heilbronn, Germany.
Kang YK; Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
Rha SY; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.
Cats A; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Plesmalaaan 121, 1066, Amsterdam, CX, Netherlands.
Tokunaga M; Division of Gastric Surgery, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, 277-8577, Japan.
Lordick F; University Cancer Center, University Medicine Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
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Źródło:
BMC cancer [BMC Cancer] 2019 May 24; Vol. 19 (1), pp. 494. Date of Electronic Publication: 2019 May 24.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Adenocarcinoma/*drug therapy
Antibodies, Monoclonal, Humanized/*therapeutic use
Antineoplastic Agents, Immunological/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Esophageal Neoplasms/*drug therapy
Esophagogastric Junction/*pathology
Receptor, ErbB-2/*metabolism
Stomach Neoplasms/*drug therapy
Trastuzumab/*therapeutic use
Adenocarcinoma/mortality ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents, Immunological/administration & dosage ; Capecitabine/therapeutic use ; Cisplatin/therapeutic use ; Esophageal Neoplasms/mortality ; Female ; Fluorouracil/therapeutic use ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Neoadjuvant Therapy ; Netherlands ; Perioperative Period ; Progression-Free Survival ; Prospective Studies ; Republic of Korea ; Stomach Neoplasms/mortality ; Trastuzumab/administration & dosage ; Treatment Outcome ; Young Adult
SCR Disease Name:
Adenocarcinoma Of Esophagus
Czasopismo naukowe
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Tytuł:
Identification of a high-risk subtype of intestinal-type Japanese gastric cancer by quantitative measurement of the luminal tumor proportion.
Autorzy:
Aoyama T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Hutchins G; Section of Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
Arai T; Department of Pathology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
Sakamaki K; Department of Biostatistics and Bioinformatics, The University of Tokyo, Tokyo, Japan.
Miyagi Y; Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan.
Tsuburaya A; Department of Surgery, Tsuboi Cancer Center Hospital, Koriyama, Japan.
Ogata T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Oshima T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Earle S; Section of Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
Yoshikawa T; Department of Gastric Surgery, National Cancer Center Hospital, Tokyo, Japan.
Grabsch HI; Section of Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.; Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, The Netherlands.
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Źródło:
Cancer medicine [Cancer Med] 2018 Oct; Vol. 7 (10), pp. 4914-4923. Date of Electronic Publication: 2018 Aug 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Intestines/*pathology
Leukocyte Common Antigens/*metabolism
Stomach Neoplasms/*surgery
Adult ; Aged ; Aged, 80 and over ; Digestive System Surgical Procedures ; Female ; Humans ; Japan ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/pathology ; Survival Analysis ; Tissue Array Analysis ; Treatment Outcome
Czasopismo naukowe
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Tytuł:
CRITICS-II: a multicentre randomised phase II trial of neo-adjuvant chemotherapy followed by surgery versus neo-adjuvant chemotherapy and subsequent chemoradiotherapy followed by surgery versus neo-adjuvant chemoradiotherapy followed by surgery in resectable gastric cancer.
Autorzy:
Slagter AE; Department of Radiation Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Jansen EPM; Department of Radiation Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
van Laarhoven HWM; Department of Medical Oncology, Academic Medical Center Amsterdam, Meibergdreef 9, 1106 AZ, Amsterdam, The Netherlands.
van Sandick JW; Department of Surgery, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
van Grieken NCT; Department of Pathology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Sikorska K; Statistical Department, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Cats A; Department of Gastroenterology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Muller-Timmermans P; Department of Radiation Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Hulshof MCCM; Department of Radiation Oncology, Academic Medical Center Amsterdam, Meibergdreef 9, 1106 AZ, Amsterdam, The Netherlands.
Boot H; Department of Gastroenterology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Los M; Department of Medical Oncology, St. Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands.
Beerepoot LV; Department of Medical Oncology, St. Elisabeth Hospital, Hilvarenbeekse Weg 60, 5022 GC, Tilburg, The Netherlands.
Peters FPJ; Department of Medical Oncology, Zuyderland Sittard-Geleen, Dr. H. van der Hoffplein 1, 6162 BG, Sittard-Geleen, The Netherlands.
Hospers GAP; Department of Medical Oncology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
van Etten B; Department of Surgery, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Hartgrink HH; Department of Surgery, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
van Berge Henegouwen MI; Department of Surgery, Academic Medical Center Amsterdam, Meibergdreef 9, 1106 AZ, Amsterdam, The Netherlands.
Nieuwenhuijzen GAP; Department of Surgery, Catharina Hospital Eindhoven, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands.
van Hillegersberg R; Department of Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3484 CX, Utrecht, The Netherlands.
van der Peet DL; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Grabsch HI; Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, P Debyelaan 25, 6229 HX, Maastricht, The Netherlands.; Department of Pathology & Tumour Biology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
Verheij M; Department of Radiation Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. .
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Źródło:
BMC cancer [BMC Cancer] 2018 Sep 10; Vol. 18 (1), pp. 877. Date of Electronic Publication: 2018 Sep 10.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Chemoradiotherapy, Adjuvant*/methods
Chemotherapy, Adjuvant*/methods
Gastrectomy*/methods
Neoadjuvant Therapy*/methods
Stomach Neoplasms/*therapy
Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Male ; Neoplasm Grading ; Neoplasm Metastasis ; Neoplasm Staging ; Quality of Life ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Treatment Outcome
Czasopismo naukowe
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Tytuł:
Prognostic value of pathological lymph node status and primary tumour regression grading following neoadjuvant chemotherapy - results from the MRC OE02 oesophageal cancer trial.
Autorzy:
Davarzani N; GROW School for Oncology and Developmental Biology, Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands.; Department of Data Science and Knowledge Engineering, Maastricht University, Maastricht, the Netherlands.
Hutchins GGA; Section of Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
West NP; Section of Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
Hewitt LC; GROW School for Oncology and Developmental Biology, Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Nankivell M; MRC Clinical Trials Unit, University College London, London, UK.
Cunningham D; Gastrointestinal and Lymphoma Unit, Royal Marsden Hospital, London, UK.
Allum WH; Department of Surgery, Royal Marsden Hospital, London, UK.
Smyth E; Gastrointestinal and Lymphoma Unit, Royal Marsden Hospital, London, UK.
Valeri N; Gastrointestinal and Lymphoma Unit, Royal Marsden Hospital, London, UK.; Department of Molecular Pathology, The Institute of Cancer Research, London, UK.
Langley RE; MRC Clinical Trials Unit, University College London, London, UK.
Grabsch HI; GROW School for Oncology and Developmental Biology, Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands.; Section of Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
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Źródło:
Histopathology [Histopathology] 2018 Jun; Vol. 72 (7), pp. 1180-1188. Date of Electronic Publication: 2018 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Esophageal Neoplasms/*pathology
Lymph Nodes/*pathology
Lymphatic Metastasis/*pathology
Adult ; Aged ; Chemotherapy, Adjuvant ; Esophageal Neoplasms/drug therapy ; Esophageal Neoplasms/surgery ; Female ; Humans ; Male ; Middle Aged ; Neoadjuvant Therapy ; Neoplasm Grading ; Prognosis
Czasopismo naukowe
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Tytuł:
Prognostic DNA methylation markers for sporadic colorectal cancer: a systematic review.
Autorzy:
Draht MXG; 1Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Goudkade D; 1Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Koch A; 1Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Grabsch HI; 1Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.; 2Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
Weijenberg MP; 3Department of Epidemiology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
van Engeland M; 1Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
Melotte V; 1Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.; 4Department of Clinical Genetics, University of Rotterdam, Rotterdam, The Netherlands.
Smits KM; 1Department of Pathology, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
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Źródło:
Clinical epigenetics [Clin Epigenetics] 2018 Mar 14; Vol. 10, pp. 35. Date of Electronic Publication: 2018 Mar 14 (Print Publication: 2018).
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
DNA Methylation*
Biomarkers, Tumor/*genetics
Colorectal Neoplasms/*genetics
CpG Islands ; Epigenesis, Genetic ; Humans ; Prognosis ; Survival Analysis
Czasopismo naukowe
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Tytuł:
Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease.
Autorzy:
Hendrikx T; Departments of Molecular Genetics, Pathology, and Internal Medicine, Division of Gastroenterology and Hepatology, School of Nutrition and Translational Research in Metabolism (NUTRIM) and School of Oncology and Developmental Biology (GROW), Maastricht University and Maastricht University Medical Center (MUMC), PO Box 616, 6200 MD, Maastricht, The Netherlands.; Departments of Laboratory Medicine, Surgery, and Internal Medicine III, Division of Gastroenterology And Hepatology, Medical University of Vienna, Vienna, Austria.; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
Watzenböck ML; Departments of Laboratory Medicine, Surgery, and Internal Medicine III, Division of Gastroenterology And Hepatology, Medical University of Vienna, Vienna, Austria.; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
Walenbergh SM; Departments of Molecular Genetics, Pathology, and Internal Medicine, Division of Gastroenterology and Hepatology, School of Nutrition and Translational Research in Metabolism (NUTRIM) and School of Oncology and Developmental Biology (GROW), Maastricht University and Maastricht University Medical Center (MUMC), PO Box 616, 6200 MD, Maastricht, The Netherlands.
Amir S; Departments of Laboratory Medicine, Surgery, and Internal Medicine III, Division of Gastroenterology And Hepatology, Medical University of Vienna, Vienna, Austria.; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
Gruber S; Departments of Laboratory Medicine, Surgery, and Internal Medicine III, Division of Gastroenterology And Hepatology, Medical University of Vienna, Vienna, Austria.; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
Kozma MO; Departments of Laboratory Medicine, Surgery, and Internal Medicine III, Division of Gastroenterology And Hepatology, Medical University of Vienna, Vienna, Austria.; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
Grabsch HI; Departments of Molecular Genetics, Pathology, and Internal Medicine, Division of Gastroenterology and Hepatology, School of Nutrition and Translational Research in Metabolism (NUTRIM) and School of Oncology and Developmental Biology (GROW), Maastricht University and Maastricht University Medical Center (MUMC), PO Box 616, 6200 MD, Maastricht, The Netherlands.
Koek GH; Departments of Molecular Genetics, Pathology, and Internal Medicine, Division of Gastroenterology and Hepatology, School of Nutrition and Translational Research in Metabolism (NUTRIM) and School of Oncology and Developmental Biology (GROW), Maastricht University and Maastricht University Medical Center (MUMC), PO Box 616, 6200 MD, Maastricht, The Netherlands.
Pierik MJ; Departments of Molecular Genetics, Pathology, and Internal Medicine, Division of Gastroenterology and Hepatology, School of Nutrition and Translational Research in Metabolism (NUTRIM) and School of Oncology and Developmental Biology (GROW), Maastricht University and Maastricht University Medical Center (MUMC), PO Box 616, 6200 MD, Maastricht, The Netherlands.
Staufer K; Departments of Laboratory Medicine, Surgery, and Internal Medicine III, Division of Gastroenterology And Hepatology, Medical University of Vienna, Vienna, Austria.
Trauner M; Departments of Laboratory Medicine, Surgery, and Internal Medicine III, Division of Gastroenterology And Hepatology, Medical University of Vienna, Vienna, Austria.
Kalhan SC; Department of Pathobiology, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA.
Jonkers D; Departments of Molecular Genetics, Pathology, and Internal Medicine, Division of Gastroenterology and Hepatology, School of Nutrition and Translational Research in Metabolism (NUTRIM) and School of Oncology and Developmental Biology (GROW), Maastricht University and Maastricht University Medical Center (MUMC), PO Box 616, 6200 MD, Maastricht, The Netherlands.
Hofker MH; Department of Pathology & Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Binder CJ; Departments of Laboratory Medicine, Surgery, and Internal Medicine III, Division of Gastroenterology And Hepatology, Medical University of Vienna, Vienna, Austria.; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
Shiri-Sverdlov R; Departments of Molecular Genetics, Pathology, and Internal Medicine, Division of Gastroenterology and Hepatology, School of Nutrition and Translational Research in Metabolism (NUTRIM) and School of Oncology and Developmental Biology (GROW), Maastricht University and Maastricht University Medical Center (MUMC), PO Box 616, 6200 MD, Maastricht, The Netherlands. .
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Źródło:
BMC medicine [BMC Med] 2016 Jul 22; Vol. 14 (1), pp. 107. Date of Electronic Publication: 2016 Jul 22.
Typ publikacji:
Journal Article
MeSH Terms:
Epitopes*
Oxidation-Reduction*
Immunoglobulin G/*blood
Immunoglobulin M/*blood
Non-alcoholic Fatty Liver Disease/*immunology
Adult ; Aged ; Biomarkers/blood ; Case-Control Studies ; Female ; Humans ; Lipid Metabolism/immunology ; Male ; Middle Aged ; Non-alcoholic Fatty Liver Disease/blood
Czasopismo naukowe
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