Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Grachtchouk Marina"" wg kryterium: Autor


Tytuł :
Constitutive Hedgehog/GLI2 signaling drives extracutaneous basaloid squamous cell carcinoma development and bone remodeling.
Autorzy :
Grachtchouk M; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Liu J; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Hutchin ME; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Harms PW; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center.
Thomas D; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center.
Wei L; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Wang A; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Cummings D; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Lowe L; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Garlick J; Division of Cancer Biology and Tissue Engineering, Tufts University School of Dental Medicine, Boston, MA, USA.
Sciubba J; The Milton J. Dance Head & Neck Center, Greater Baltimore Medical Center, Baltimore, MD, USA.
Chinnaiyan AM; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center.; Department of Urology, University of Michigan, Ann Arbor, MI, USA.
Verhaegen ME; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Dlugosz AA; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center.; Department of Cell & Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Pokaż więcej
Źródło :
Carcinogenesis [Carcinogenesis] 2021 Jun 12. Date of Electronic Publication: 2021 Jun 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin.
Autorzy :
Veniaminova NA; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Grachtchouk M; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Doane OJ; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Peterson JK; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Quigley DA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA 94158, USA.
Lull MV; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Pyrozhenko DV; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Nair RR; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Patrick MT; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine & Bioinformatics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
Balmain A; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
Dlugosz AA; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Tsoi LC; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine & Bioinformatics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
Wong SY; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: .
Pokaż więcej
Źródło :
Developmental cell [Dev Cell] 2019 Nov 04; Vol. 51 (3), pp. 326-340.e4. Date of Electronic Publication: 2019 Sep 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Stem Cell Niche*
Sebaceous Glands/*cytology
Skin/*cytology
Stem Cells/*cytology
Animals ; Cell Differentiation ; Female ; Hedgehog Proteins/metabolism ; Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism ; Keratins/metabolism ; Male ; Meibomian Glands/metabolism ; Mice, Knockout ; Mutation/genetics ; Receptors, Notch/genetics
Czasopismo naukowe
Tytuł :
Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib.
Autorzy :
Kumari A; Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI 48109.
Ermilov AN; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109.
Grachtchouk M; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109.
Dlugosz AA; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109.
Allen BL; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109.
Bradley RM; Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI 48109.
Mistretta CM; Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI 48109; .
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Nov 28; Vol. 114 (48), pp. E10369-E10378. Date of Electronic Publication: 2017 Nov 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*adverse effects
Biphenyl Compounds/*adverse effects
Dysgeusia/*physiopathology
Pyridines/*adverse effects
Signal Transduction/*drug effects
Taste/*drug effects
Tongue/*physiopathology
Animals ; Carcinoma, Basal Cell/drug therapy ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Chorda Tympani Nerve/drug effects ; Chorda Tympani Nerve/physiopathology ; Disease Models, Animal ; Dysgeusia/chemically induced ; Dysgeusia/pathology ; Hedgehog Proteins/antagonists & inhibitors ; Hedgehog Proteins/metabolism ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Recovery of Function ; Skin Neoplasms/drug therapy ; Smoothened Receptor/antagonists & inhibitors ; Smoothened Receptor/genetics ; Smoothened Receptor/metabolism ; Stem Cells/drug effects ; Taste/physiology ; Taste Buds/cytology ; Taste Buds/drug effects ; Taste Buds/pathology ; Taste Buds/physiopathology ; Tongue/drug effects ; Tongue/innervation
Czasopismo naukowe
Tytuł :
Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.
Autorzy :
Ermilov AN; Department of Dermatology, Medical School, University of Michigan, Ann Arbor, Michigan, United States of America.
Kumari A; Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.
Li L; Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.
Joiner AM; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, Michigan, United States of America.
Grachtchouk MA; Department of Dermatology, Medical School, University of Michigan, Ann Arbor, Michigan, United States of America.
Allen BL; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, Michigan, United States of America.
Dlugosz AA; Department of Dermatology, Medical School, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, Michigan, United States of America.
Mistretta CM; Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.
Pokaż więcej
Źródło :
PLoS genetics [PLoS Genet] 2016 Nov 28; Vol. 12 (11), pp. e1006442. Date of Electronic Publication: 2016 Nov 28 (Print Publication: 2016).
Typ publikacji :
Journal Article
MeSH Terms :
Hedgehog Proteins/*genetics
Taste/*genetics
Taste Buds/*metabolism
Tongue/*metabolism
Animals ; Epithelial Cells/metabolism ; Epithelium/metabolism ; Hedgehog Proteins/antagonists & inhibitors ; Hedgehog Proteins/metabolism ; Mice ; Nerve Fibers/metabolism ; Signal Transduction ; Stromal Cells/metabolism ; Taste Buds/growth & development ; Taste Perception/genetics
Czasopismo naukowe
Tytuł :
Transgenic expression of human amphiregulin in mouse skin: inflammatory epidermal hyperplasia and enlarged sebaceous glands.
Autorzy :
Li Y; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
Stoll SW; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
Sekhon S; Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA.
Talsma C; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
Camhi MI; Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA.
Jones JL; Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA.
Lambert S; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
Marley H; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
Rittié L; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
Grachtchouk M; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
Fritz Y; Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA.
Ward NL; Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA.
Elder JT; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.; Ann Arbor VA Hospital, Ann Arbor, MI, USA.
Pokaż więcej
Źródło :
Experimental dermatology [Exp Dermatol] 2016 Mar; Vol. 25 (3), pp. 187-93. Date of Electronic Publication: 2016 Jan 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Amphiregulin/*genetics
Amphiregulin/*metabolism
Skin/*metabolism
3' Untranslated Regions ; 5' Untranslated Regions ; Animals ; Cattle ; Epidermis/pathology ; ErbB Receptors/metabolism ; Homeostasis ; Humans ; Hyperplasia/metabolism ; Inflammation ; Ligands ; Mice ; Mice, Transgenic ; Phenotype ; Promoter Regions, Genetic ; Sebaceous Glands/metabolism
Czasopismo naukowe
Tytuł :
Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.
Autorzy :
Syu LJ; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Zhao X; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Zhang Y; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
Grachtchouk M; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Demitrack E; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
Ermilov A; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Wilbert DM; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Zheng X; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Kaatz A; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Greenson JK; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Gumucio DL; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Merchant JL; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA.
di Magliano MP; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
Samuelson LC; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Dlugosz AA; Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Pokaż więcej
Źródło :
Oncotarget [Oncotarget] 2016 Mar 01; Vol. 7 (9), pp. 10255-70.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Adenocarcinoma/*pathology
Hedgehog Proteins/*metabolism
Kruppel-Like Transcription Factors/*metabolism
Neoplastic Stem Cells/*pathology
Receptors, G-Protein-Coupled/*metabolism
Stomach Neoplasms/*pathology
TOR Serine-Threonine Kinases/*metabolism
Animals ; Disease Models, Animal ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition ; Intestinal Mucosa/cytology ; Intestinal Mucosa/metabolism ; Mice ; Mice, Nude ; Ribosomal Protein S6 Kinases/metabolism ; Sirolimus/therapeutic use ; Snail Family Transcription Factors/metabolism ; Wnt Signaling Pathway ; Zinc Finger Protein Gli2 ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance.
Autorzy :
Liu HX; Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Ermilov A
Grachtchouk M
Li L
Gumucio DL
Dlugosz AA
Mistretta CM
Pokaż więcej
Źródło :
Developmental biology [Dev Biol] 2013 Oct 01; Vol. 382 (1), pp. 82-97. Date of Electronic Publication: 2013 Aug 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Signal Transduction*
Epithelium/*embryology
Epithelium/*metabolism
Hedgehog Proteins/*metabolism
Taste Buds/*embryology
Taste Buds/*metabolism
Aging/metabolism ; Animals ; Animals, Newborn ; Cell Compartmentation ; Cell Lineage ; Cell Proliferation ; Cellular Microenvironment ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Female ; Kruppel-Like Transcription Factors/metabolism ; Ligands ; Mesoderm/cytology ; Mesoderm/embryology ; Mesoderm/metabolism ; Mice ; Mice, Inbred C57BL ; Patched Receptors ; Patched-1 Receptor ; Receptors, Cell Surface/metabolism ; Taste Buds/cytology ; Taste Buds/ultrastructure ; Time Factors ; Zinc Finger Protein GLI1 ; Zinc Finger Protein Gli2
Czasopismo naukowe
Tytuł :
Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.
Autorzy :
Grachtchouk M; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Pero J
Yang SH
Ermilov AN
Michael LE
Wang A
Wilbert D
Patel RM
Ferris J
Diener J
Allen M
Lim S
Syu LJ
Verhaegen M
Dlugosz AA
Pokaż więcej
Źródło :
The Journal of clinical investigation [J Clin Invest] 2011 May; Vol. 121 (5), pp. 1768-81. Date of Electronic Publication: 2011 Apr 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Basal Cell/*metabolism
Epithelial Cells/*cytology
Hair Follicle/*metabolism
Skin Neoplasms/*metabolism
Stem Cells/*cytology
Alleles ; Animals ; Epidermis/metabolism ; Hamartoma/metabolism ; Hedgehog Proteins/metabolism ; Humans ; Hyperplasia ; Kruppel-Like Transcription Factors/metabolism ; Mice ; Mice, Transgenic ; Phenotype ; Protein Structure, Tertiary ; Signal Transduction ; Zinc Finger Protein Gli2
Czasopismo naukowe
Tytuł :
Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways.
Autorzy :
Sharov AA; Centre for Skin Sciences, School of Life Sciences, University of Bradford, Bradford, UK.
Mardaryev AN
Sharova TY
Grachtchouk M
Atoyan R
Byers HR
Seykora JT
Overbeek P
Dlugosz A
Botchkarev VA
Pokaż więcej
Źródło :
The American journal of pathology [Am J Pathol] 2009 Sep; Vol. 175 (3), pp. 1303-14. Date of Electronic Publication: 2009 Aug 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Morphogenetic Proteins/*antagonists & inhibitors
Carrier Proteins/*genetics
Skin Neoplasms/*metabolism
Adult ; Aged ; Animals ; Bone Morphogenetic Proteins/metabolism ; Carrier Proteins/biosynthesis ; Cell Transformation, Neoplastic ; Female ; Hair Follicle/metabolism ; Hair Follicle/pathology ; Hedgehog Proteins/metabolism ; Humans ; Keratinocytes/metabolism ; Keratinocytes/pathology ; Male ; Mice ; Mice, Transgenic ; Middle Aged ; Signal Transduction/genetics ; Skin/metabolism ; Skin/pathology ; Skin Neoplasms/etiology ; Skin Neoplasms/pathology ; Wnt Proteins/metabolism
Czasopismo naukowe
Tytuł :
Lack of evidence for activation of the hedgehog pathway in psoriasis.
Autorzy :
Gudjonsson JE; Department of Dermatology, University of Michigan Medical Center, Ann Arbor, Michigan, USA. />Aphale A
Grachtchouk M
Ding J
Nair RP
Wang T
Voorhees JJ
Dlugosz AA
Elder JT
Pokaż więcej
Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2009 Mar; Vol. 129 (3), pp. 635-40. Date of Electronic Publication: 2008 Aug 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Hedgehog Proteins/*metabolism
Psoriasis/*metabolism
Biopsy ; Gene Expression Profiling ; Humans ; In Situ Hybridization ; Models, Biological ; Oligonucleotide Array Sequence Analysis ; Patched Receptors ; Patched-1 Receptor ; RNA, Messenger/metabolism ; Receptors, Cell Surface/genetics ; Receptors, Cell Surface/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction ; Skin/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Zinc Finger Protein GLI1
Czasopismo naukowe
Tytuł :
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.
Autorzy :
Dentice M; Department of Molecular and Clinical Endocrinology and Oncology, University of Naples Federico II, 80131 Naples, Italy, and Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA 02115, USA.
Luongo C
Huang S
Ambrosio R
Elefante A
Mirebeau-Prunier D
Zavacki AM
Fenzi G
Grachtchouk M
Hutchin M
Dlugosz AA
Bianco AC
Missero C
Larsen PR
Salvatore D
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2007 Sep 04; Vol. 104 (36), pp. 14466-71. Date of Electronic Publication: 2007 Aug 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hedgehog Proteins/*metabolism
Hormone Antagonists/*metabolism
Iodide Peroxidase/*metabolism
Keratinocytes/*cytology
Skin Neoplasms/*metabolism
Skin Neoplasms/*pathology
Thyroid Hormones/*metabolism
Adenocarcinoma/genetics ; Adenocarcinoma/metabolism ; Adenocarcinoma/pathology ; Animals ; Cell Proliferation ; Cells, Cultured ; Female ; Gene Expression Regulation, Neoplastic ; Hedgehog Proteins/genetics ; Keratinocytes/metabolism ; Keratinocytes/pathology ; Mice ; Mice, Transgenic ; Oncogene Proteins/genetics ; Oncogene Proteins/metabolism ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Zinc Finger Protein GLI1
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies