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Tytuł :
Strategies and Approaches for Discovery of Small Molecule Disruptors of Biofilm Physiology.
Autorzy :
Trebino MA; Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064, USA.
Shingare RD; Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA.
MacMillan JB; Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA.
Yildiz FH; Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064, USA.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 29; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Biofilms/*drug effects
Extracellular Polymeric Substance Matrix/*drug effects
Gram-Negative Bacteria/*drug effects
Gram-Positive Bacteria/*drug effects
Small Molecule Libraries/*pharmacology
Anti-Bacterial Agents/biosynthesis ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/isolation & purification ; Bacterial Proteins/antagonists & inhibitors ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Biofilms/growth & development ; Cyclic GMP/antagonists & inhibitors ; Cyclic GMP/chemistry ; Cyclic GMP/metabolism ; Drug Design ; Drug Discovery ; Drug Resistance, Bacterial/drug effects ; Extracellular Polymeric Substance Matrix/chemistry ; Extracellular Polymeric Substance Matrix/metabolism ; Gram-Negative Bacteria/growth & development ; Gram-Negative Bacteria/pathogenicity ; Gram-Positive Bacteria/growth & development ; Gram-Positive Bacteria/pathogenicity ; Lipids/antagonists & inhibitors ; Lipids/chemistry ; Microbial Sensitivity Tests ; Nucleic Acids/antagonists & inhibitors ; Nucleic Acids/chemistry ; Nucleic Acids/metabolism ; Polysaccharides, Bacterial/antagonists & inhibitors ; Polysaccharides, Bacterial/chemistry ; Polysaccharides, Bacterial/metabolism ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/isolation & purification ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents.
Autorzy :
Hansa RK; Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR, 72467, USA.
Khan MMK; Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR, 72467, USA.
Frangie MM; Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR, 72467, USA.
Gilmore DF; Department of Biological Sciences, College of Science and Mathematics, Arkansas State University, Jonesboro, AR, 72467, USA.
Shelton RS; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR, 72205, USA.
Savenka AV; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR, 72205, USA.
Basnakian AG; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR, 72205, USA; Central Arkansas Veterans Healthcare System, W. 7th St., Little Rock, AR, 72205, USA.
Shuttleworth SL; Department of Microbiology and Immunology, Department of Orthopaedic Surgery, Center for Microbial Pathogenesis and Host Inflammatory Responses University of Arkansas for Medical Sciences, 4301 W. Markham, Little Rock, AR, 72205, USA.
Smeltzer MS; Department of Microbiology and Immunology, Department of Orthopaedic Surgery, Center for Microbial Pathogenesis and Host Inflammatory Responses University of Arkansas for Medical Sciences, 4301 W. Markham, Little Rock, AR, 72205, USA.
Alam MA; Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR, 72467, USA. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Jul 05; Vol. 219, pp. 113402. Date of Electronic Publication: 2021 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Aniline Compounds/*chemistry
Anti-Bacterial Agents/*pharmacology
Gram-Positive Bacteria/*drug effects
Pyrazoles/*chemistry
Aniline Compounds/chemical synthesis ; Aniline Compounds/pharmacology ; Anti-Bacterial Agents/chemistry ; Biofilms/drug effects ; Cell Line ; Cell Survival/drug effects ; Drug Resistance, Bacterial/drug effects ; Enterococcus faecalis/drug effects ; Enterococcus faecalis/isolation & purification ; Enterococcus faecalis/physiology ; Gram-Positive Bacteria/isolation & purification ; Humans ; Liver/drug effects ; Liver/metabolism ; Microbial Sensitivity Tests ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/isolation & purification ; Staphylococcus aureus/physiology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection.
Autorzy :
Avican K; Department of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden. .
Aldahdooh J; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Togninalli M; Department for Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.; Swiss Institute for Bioinformatics, Lausanne, Switzerland.
Mahmud AKMF; Department of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden.
Tang J; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Borgwardt KM; Department for Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.; Swiss Institute for Bioinformatics, Lausanne, Switzerland.
Rhen M; Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institute, Stockholm, Sweden.
Fällman M; Department of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 02; Vol. 12 (1), pp. 3282. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Bacterial*
Transcriptome*
Gram-Negative Bacteria/*genetics
Gram-Positive Bacteria/*genetics
RNA, Bacterial/*genetics
Stress, Physiological/*genetics
Adaptation, Physiological/genetics ; Atlases as Topic ; Databases, Genetic ; Gene Expression Profiling ; Genes, Bacterial ; Gram-Negative Bacteria/classification ; Gram-Negative Bacteria/metabolism ; Gram-Negative Bacteria/pathogenicity ; Gram-Positive Bacteria/classification ; Gram-Positive Bacteria/metabolism ; Gram-Positive Bacteria/pathogenicity ; Host Microbial Interactions/genetics ; Humans ; Internet ; Microbiota/genetics ; Phylogeny ; RNA, Bacterial/metabolism
Czasopismo naukowe
Tytuł :
Development of a novel selective medium for culture of Gram-negative bacteria.
Autorzy :
Al-Blooshi SY; Department of Medical Microbiology and Immunology, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Latif MAA; Department of Medical Microbiology and Immunology, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Sabaneh NK; Department of Medical Microbiology and Immunology, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Mgaogao M; Department of Medical Microbiology and Immunology, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.; Central Research Laboratory, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Hossain A; Department of Medical Microbiology and Immunology, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates. .; Central Research Laboratory, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates. .
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Źródło :
BMC research notes [BMC Res Notes] 2021 May 29; Vol. 14 (1), pp. 211. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Gram-Negative Bacteria*
Gram-Positive Bacteria*
Agar ; Anti-Bacterial Agents/pharmacology ; Culture Media
Czasopismo naukowe
Tytuł :
Nisin resistance in Gram-positive bacteria and approaches to circumvent resistance for successful therapeutic use.
Autorzy :
Barbosa AAT; Programa de Pós-Graduação em Biologia Parasitária, Universidade Federal de Sergipe, São Cristóvão, Brasil.
de Melo MR; Universidade Estadual de Londrina, Londrina, Brazil.
da Silva CMR; Programa de Pós-Graduação em Biologia Parasitária, Universidade Federal de Sergipe, São Cristóvão, Brasil.
Jain S; Programa de Pós-Graduação em Biotecnologia Industrial, Universidade Tiradentes, Sergipe, Brasil.
Dolabella SS; Programa de Pós-Graduação em Biologia Parasitária, Universidade Federal de Sergipe, São Cristóvão, Brasil.
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Źródło :
Critical reviews in microbiology [Crit Rev Microbiol] 2021 May; Vol. 47 (3), pp. 376-385. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Resistance, Bacterial*
Anti-Bacterial Agents/*pharmacology
Bacterial Infections/*drug therapy
Gram-Positive Bacteria/*drug effects
Nisin/*pharmacology
Animals ; Bacterial Infections/microbiology ; Gram-Positive Bacteria/genetics ; Gram-Positive Bacteria/physiology ; Humans
Czasopismo naukowe
Tytuł :
Passive Diffusion of Ciprofloxacin and its Metalloantibiotic: A Computational and Experimental study.
Autorzy :
Sousa CF; LAQV, REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal. Electronic address: .
Coimbra JTS; LAQV, REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal. Electronic address: .
Ferreira M; LAQV, REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal. Electronic address: .
Pereira-Leite C; LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. Electronic address: .
Reis S; LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. Electronic address: .
Ramos MJ; LAQV, REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal. Electronic address: .
Fernandes PA; LAQV, REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal. Electronic address: .
Gameiro P; LAQV, REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Apr 30; Vol. 433 (9), pp. 166911. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diffusion*
Gram-Positive Bacteria*/chemistry
Gram-Positive Bacteria*/cytology
Gram-Positive Bacteria*/metabolism
Anti-Bacterial Agents/*chemistry
Anti-Bacterial Agents/*metabolism
Cell Membrane/*metabolism
Ciprofloxacin/*chemistry
Ciprofloxacin/*metabolism
Copper/*metabolism
Cardiolipins/metabolism ; Cell Membrane/chemistry ; Copper/chemistry ; Drug Resistance, Multiple, Bacterial ; Lipid Bilayers/chemistry ; Lipid Bilayers/metabolism ; Molecular Dynamics Simulation ; Phosphatidylglycerols/metabolism ; Protons ; Thermodynamics
Czasopismo naukowe
Tytuł :
In Vitro and In Silico Screening and Characterization of Antimicrobial Napin Bioactive Protein in Brassica juncea and Moringa oleifera .
Autorzy :
Chandrashekar S; Department of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon 24341, Korea.; Department of Physiology, Bharath Institute of Higher Education and Research, Chennai 600073, India.
Vijayakumar R; Department of Physiology, Bharath Institute of Higher Education and Research, Chennai 600073, India.
Chelliah R; Department of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon 24341, Korea.
Daliri EB; Department of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon 24341, Korea.
Madar IH; Department of Biotechnology, School of Biotechnology and Genetic Engineering, Bharathidasan University, Tiruchirappalli 620024, India.
Sultan G; Department of Computer Science, Aligarh Muslim University, Aligarh 202002, India.
Rubab M; Department of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon 24341, Korea.; School of Food and Agricultural Sciences, University of Management and Technology, Lahore 54770, Pakistan.
Elahi F; Department of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon 24341, Korea.
Yeon SJ; Department of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon 24341, Korea.
Oh DH; Department of Food Science and Biotechnology, College of Agriculture and Life Science, Kangwon National University, Chuncheon 24341, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 05; Vol. 26 (7). Date of Electronic Publication: 2021 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
2S Albumins, Plant/*chemistry
Anti-Bacterial Agents/*chemistry
Gram-Negative Bacteria/*drug effects
Gram-Positive Bacteria/*drug effects
Moringa oleifera/*chemistry
Mustard Plant/*chemistry
2S Albumins, Plant/isolation & purification ; 2S Albumins, Plant/pharmacology ; Amidohydrolases/antagonists & inhibitors ; Amidohydrolases/chemistry ; Amidohydrolases/genetics ; Amidohydrolases/metabolism ; Anti-Bacterial Agents/isolation & purification ; Anti-Bacterial Agents/pharmacology ; Binding Sites ; DNA Topoisomerases, Type II/chemistry ; DNA Topoisomerases, Type II/genetics ; DNA Topoisomerases, Type II/metabolism ; Gram-Negative Bacteria/enzymology ; Gram-Negative Bacteria/growth & development ; Gram-Positive Bacteria/enzymology ; Gram-Positive Bacteria/growth & development ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs
Czasopismo naukowe
Tytuł :
Biodiversity, Bioactivity, and Metabolites of High Desert Derived Oregonian Soil Bacteria.
Autorzy :
Zhu C; Department of Chemistry, Oregon State University, Corvallis, Oregon, 97331, USA.; Whitney Laboratory for Marine Bioscience, Department of Chemistry, University of Florida, St. Augustine, Florida, 32080, USA.
Lew CI; Department of Chemistry, Oregon State University, Corvallis, Oregon, 97331, USA.
Neuhaus GF; Department of Chemistry, Oregon State University, Corvallis, Oregon, 97331, USA.
Adpressa DA; Department of Chemistry, Oregon State University, Corvallis, Oregon, 97331, USA.
Zakharov LN; Department of Chemistry, Oregon State University, Corvallis, Oregon, 97331, USA.
Kaweesa EN; Department of Chemistry, Oregon State University, Corvallis, Oregon, 97331, USA.; Whitney Laboratory for Marine Bioscience, Department of Chemistry, University of Florida, St. Augustine, Florida, 32080, USA.
Plitzko B; Department of Chemistry, Oregon State University, Corvallis, Oregon, 97331, USA.
Loesgen S; Department of Chemistry, Oregon State University, Corvallis, Oregon, 97331, USA.; Whitney Laboratory for Marine Bioscience, Department of Chemistry, University of Florida, St. Augustine, Florida, 32080, USA.
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2021 Apr; Vol. 18 (4), pp. e2100046. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antineoplastic Agents/*pharmacology
Biological Products/*pharmacology
Gram-Negative Bacteria/*drug effects
Gram-Positive Bacteria/*drug effects
Soil/*chemistry
Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/metabolism ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/metabolism ; Biological Products/chemistry ; Biological Products/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Gram-Negative Bacteria/chemistry ; Gram-Negative Bacteria/isolation & purification ; Gram-Positive Bacteria/chemistry ; Gram-Positive Bacteria/isolation & purification ; Humans ; Microbial Sensitivity Tests ; Molecular Structure ; Principal Component Analysis ; RNA, Ribosomal, 16S/genetics ; RNA, Ribosomal, 16S/metabolism ; Soil Microbiology
Czasopismo naukowe
Tytuł :
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Autorzy :
Crowe-McAuliffe C; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.
Murina V; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden.
Turnbull KJ; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden.
Kasari M; University of Tartu, Institute of Technology, Tartu, Estonia.
Mohamad M; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
Polte C; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.
Takada H; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden.
Vaitkevicius K; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden.
Johansson J; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden.
Ignatova Z; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.
Atkinson GC; Department of Molecular Biology, Umeå University, Umeå, Sweden.
O'Neill AJ; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
Hauryliuk V; Department of Molecular Biology, Umeå University, Umeå, Sweden. .; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden. .; University of Tartu, Institute of Technology, Tartu, Estonia. .; Department of Experimental Medical Science, Lund University, Lund, Sweden. .
Wilson DN; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 11; Vol. 12 (1), pp. 3577. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Diterpenes/*pharmacology
Drug Resistance, Bacterial/*drug effects
Gram-Positive Bacteria/*drug effects
Lincosamides/*pharmacology
Polycyclic Compounds/*pharmacology
Streptogramins/*pharmacology
ATP-Binding Cassette Transporters/chemistry ; ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/metabolism ; Adhesins, Bacterial/chemistry ; Adhesins, Bacterial/genetics ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Binding Sites ; Cryoelectron Microscopy ; Drug Resistance, Bacterial/genetics ; Gram-Positive Bacteria/genetics ; Models, Molecular ; Peptidyl Transferases/metabolism ; Protein Conformation ; RNA, Messenger ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł :
Zeta potential beyond materials science: Applications to bacterial systems and to the development of novel antimicrobials.
Autorzy :
Ferreyra Maillard APV; Laboratorio de Compuestos Bioactivos, Centro de Investigaciones en Biofísica Aplicada y Alimentos (CIBAAL), CONICET - Universidad Nacional de Santiago del Estero, RN 9, Km 1125, 4206 Santiago del Estero, Argentina.
Espeche JC; Laboratorio de Compuestos Bioactivos, Centro de Investigaciones en Biofísica Aplicada y Alimentos (CIBAAL), CONICET - Universidad Nacional de Santiago del Estero, RN 9, Km 1125, 4206 Santiago del Estero, Argentina.
Maturana P; Laboratorio de Compuestos Bioactivos, Centro de Investigaciones en Biofísica Aplicada y Alimentos (CIBAAL), CONICET - Universidad Nacional de Santiago del Estero, RN 9, Km 1125, 4206 Santiago del Estero, Argentina.
Cutro AC; Laboratorio de Compuestos Bioactivos, Centro de Investigaciones en Biofísica Aplicada y Alimentos (CIBAAL), CONICET - Universidad Nacional de Santiago del Estero, RN 9, Km 1125, 4206 Santiago del Estero, Argentina; Facultad de Ciencias Médicas, Universidad Nacional de Santiago del Estero, Calle Reforma del 18 N 1234, 4200 Santiago del Estero, Argentina. Electronic address: .
Hollmann A; Laboratorio de Compuestos Bioactivos, Centro de Investigaciones en Biofísica Aplicada y Alimentos (CIBAAL), CONICET - Universidad Nacional de Santiago del Estero, RN 9, Km 1125, 4206 Santiago del Estero, Argentina; Laboratorio de Microbiología Molecular, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Saenz Peña 352, B1876BXD Bernal, Argentina. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2021 Jun 01; Vol. 1863 (6), pp. 183597. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Anti-Bacterial Agents/*chemistry
Gram-Negative Bacteria/*physiology
Gram-Positive Bacteria/*physiology
Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/metabolism ; Antimicrobial Cationic Peptides/pharmacology ; Cell Wall/chemistry ; Cell Wall/drug effects ; Cell Wall/metabolism ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Membrane Potentials/drug effects ; Nanoparticles/chemistry ; Nanoparticles/metabolism ; Nanoparticles/toxicity ; Surface Properties
Czasopismo naukowe
Tytuł :
Evaluation and validation of Biolog OmniLog system for antibacterial activity assays.
Autorzy :
Cruz CD; Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Esteve P; Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Tammela P; Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
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Źródło :
Letters in applied microbiology [Lett Appl Microbiol] 2021 May; Vol. 72 (5), pp. 589-595. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Gram-Negative Bacteria/*drug effects
Gram-Positive Bacteria/*drug effects
Automation, Laboratory ; Ciprofloxacin/pharmacology ; Gram-Negative Bacteria/growth & development ; Gram-Positive Bacteria/growth & development ; Humans ; Linezolid/pharmacology ; Microbial Sensitivity Tests/methods ; Piperacillin/pharmacology
Czasopismo naukowe
Tytuł :
Expression of Anti-Lipopolysaccharide Factor Isoform 3 in Chlamydomonas reinhardtii Showing High Antimicrobial Activity.
Autorzy :
Li A; Shenzhen Key Laboratory of Marine Bioresource & Eco-Environmental Science, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Huang R; Shenzhen Key Laboratory of Marine Bioresource & Eco-Environmental Science, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Wang C; Shenzhen Key Laboratory of Marine Bioresource & Eco-Environmental Science, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.; Guangdong Technology Research Center for Marine Algal Bioengineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Hu Q; Shenzhen Key Laboratory of Marine Bioresource & Eco-Environmental Science, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.; Guangdong Technology Research Center for Marine Algal Bioengineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Li H; Shenzhen Key Laboratory of Marine Bioresource & Eco-Environmental Science, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.; Guangdong Technology Research Center for Marine Algal Bioengineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Li X; Department of Journal of Shenzhen University Science and Engineering, Shenzhen University, Shenzhen 518060, China.
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Źródło :
Marine drugs [Mar Drugs] 2021 Apr 23; Vol. 19 (5). Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Chlamydomonas reinhardtii/*metabolism
Gram-Negative Bacteria/*drug effects
Gram-Positive Bacteria/*drug effects
Penaeidae/*metabolism
Pore Forming Cytotoxic Proteins/*pharmacology
Animals ; Anti-Bacterial Agents/biosynthesis ; Chlamydomonas reinhardtii/genetics ; Gene Expression Regulation, Bacterial ; Gram-Negative Bacteria/growth & development ; Gram-Positive Bacteria/growth & development ; Pore Forming Cytotoxic Proteins/biosynthesis ; Pore Forming Cytotoxic Proteins/genetics
Czasopismo naukowe
Tytuł :
Antimicrobial and Antibiofilm Activities of the Fungal Metabolites Isolated from the Marine Endophytes Epicoccum nigrum M13 and Alternaria alternata 13A.
Autorzy :
Qader MM; School of Computing, Engineering, & Physical Sciences, University of the West of Scotland, Paisley PA1 2BE, UK.; National Institute of Fundamental Studies, Hantana Road, Kandy 20000, Sri Lanka.
Hamed AA; National Research Centre, Microbial Chemistry Department, 33 El-Buhouth Street, Dokki, Giza 12622, Egypt.
Soldatou S; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.
Abdelraof M; National Research Centre, Microbial Chemistry Department, 33 El-Buhouth Street, Dokki, Giza 12622, Egypt.
Elawady ME; National Research Centre, Microbial Biotechnology Department, 33 El-Buhouth Street, Dokki, Giza 12622, Egypt.
Hassane ASI; School of Computing, Engineering, & Physical Sciences, University of the West of Scotland, Paisley PA1 2BE, UK.; Aberdeen Royal Infirmary, Foresterhill Health Campus, Aberdeen AB25 2ZN, UK.
Belbahri L; Laboratory of Soil Biology, University of Neuchatel, 2000 Neuchatel, Switzerland.
Ebel R; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.
Rateb ME; School of Computing, Engineering, & Physical Sciences, University of the West of Scotland, Paisley PA1 2BE, UK.
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Źródło :
Marine drugs [Mar Drugs] 2021 Apr 20; Vol. 19 (4). Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Alternaria/*metabolism
Anti-Bacterial Agents/*pharmacology
Ascomycota/*metabolism
Biofilms/*drug effects
Gram-Negative Aerobic Bacteria/*drug effects
Gram-Positive Bacteria/*drug effects
Anti-Bacterial Agents/isolation & purification ; Biofilms/growth & development ; Fermentation ; Gram-Negative Aerobic Bacteria/growth & development ; Gram-Positive Bacteria/growth & development ; Microbial Sensitivity Tests ; Molecular Structure ; Structure-Activity Relationship
SCR Organism :
Alternaria alternata; Epicoccum nigrum
Czasopismo naukowe
Tytuł :
In vitro Antibacterial Effect of Polyglycerol Monolaurates against Gram-Bacteria and Understanding the Underlying Mechanism.
Autorzy :
Zhao F; School of Light Industry, Beijing Technology and Business University.
Wang W; School of Light Industry, Beijing Technology and Business University.; China Rural Technology Development Center.
Zhang G; School of Light Industry, Beijing Technology and Business University.
Zhang J; School of Light Industry, Beijing Technology and Business University.
Liu C; School of Light Industry, Beijing Technology and Business University.
Xu B; School of Light Industry, Beijing Technology and Business University.
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Źródło :
Journal of oleo science [J Oleo Sci] 2021 Apr 02; Vol. 70 (4), pp. 571-580. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents*
Emulsifying Agents*
Food Additives*
Glycerol/*pharmacology
Gram-Negative Bacteria/*drug effects
Gram-Positive Bacteria/*drug effects
Laurates/*pharmacology
Polymers/*pharmacology
Cell Membrane/drug effects ; Cell Membrane Permeability/drug effects ; Dose-Response Relationship, Drug ; Drug Resistance, Bacterial ; Food Microbiology ; Glycerol/chemistry ; Gram-Negative Bacteria/cytology ; Gram-Positive Bacteria/cytology ; Laurates/chemistry ; Microbial Sensitivity Tests ; Polymers/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Long-distance electron transfer in a filamentous Gram-positive bacterium.
Autorzy :
Yang Y; Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China.; State Key Laboratory of Applied Microbiology Southern China, Guangzhou, China.; Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangzhou, China.
Wang Z; Interdisciplinary Nanoscience Center (iNANO), Sino-Danish Center for Education and Research (SDC), Aarhus University, Aarhus, Denmark.; College of Materials Science and Engineering, Sichuan University, Chengdu, China.
Gan C; Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China.
Klausen LH; Interdisciplinary Nanoscience Center (iNANO), Sino-Danish Center for Education and Research (SDC), Aarhus University, Aarhus, Denmark.
Bonné R; X-LAB, Hasselt University, Diepenbeek, Belgium.
Kong G; Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China.
Luo D; Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China.
Meert M; X-LAB, Hasselt University, Diepenbeek, Belgium.
Zhu C; Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China.
Sun G; Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China.
Guo J; State Key Laboratory of Applied Microbiology Southern China, Guangzhou, China.
Ma Y; School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Bjerg JT; Center for Electromicrobiology, Aarhus University, Aarhus, Denmark.
Manca J; X-LAB, Hasselt University, Diepenbeek, Belgium.
Xu M; Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China. .; State Key Laboratory of Applied Microbiology Southern China, Guangzhou, China. .; Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangzhou, China. .
Nielsen LP; Center for Electromicrobiology, Aarhus University, Aarhus, Denmark.
Dong M; Interdisciplinary Nanoscience Center (iNANO), Sino-Danish Center for Education and Research (SDC), Aarhus University, Aarhus, Denmark. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 17; Vol. 12 (1), pp. 1709. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Electron Transport/*physiology
Gram-Positive Bacteria/*metabolism
Bacillaceae/cytology ; Bacillaceae/growth & development ; Bacillaceae/metabolism ; Bioelectric Energy Sources/microbiology ; Electric Conductivity ; Electrodes/microbiology ; Fimbriae, Bacterial/metabolism ; Fimbriae, Bacterial/ultrastructure ; Gram-Positive Bacteria/cytology ; Gram-Positive Bacteria/growth & development ; Graphite ; Microscopy, Atomic Force ; Nanowires
SCR Organism :
Lysinibacillus varians
Czasopismo naukowe
Tytuł :
Characterization and function of membrane vesicles in Gram-positive bacteria.
Autorzy :
Cao Y; Department of Preventive Dentistry, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, China.
Lin H; Department of Preventive Dentistry, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China. .; Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, China. .
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2021 Mar; Vol. 105 (5), pp. 1795-1801. Date of Electronic Publication: 2021 Feb 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Extracellular Vesicles*
Gram-Positive Bacteria*
Bacteria ; Membranes
Czasopismo naukowe
Tytuł :
Glycoconjugate pathway connections revealed by sequence similarity network analysis of the monotopic phosphoglycosyl transferases.
Autorzy :
O'Toole KH; Department of Chemistry, Boston University, Boston, MA 02215.
Imperiali B; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139; .; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
Allen KN; Department of Chemistry, Boston University, Boston, MA 02215; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 26; Vol. 118 (4).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Bacterial Proteins/*chemistry
Glycoconjugates/*chemistry
Glycosyltransferases/*chemistry
Gram-Negative Bacteria/*enzymology
Gram-Positive Bacteria/*enzymology
Polysaccharides/*chemistry
Amino Acid Sequence ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Binding Sites ; Cytoplasm/enzymology ; Cytoplasm/genetics ; Evolution, Molecular ; Gene Expression ; Gene Regulatory Networks ; Glycoconjugates/metabolism ; Glycosyltransferases/genetics ; Glycosyltransferases/metabolism ; Gram-Negative Bacteria/classification ; Gram-Negative Bacteria/genetics ; Gram-Positive Bacteria/classification ; Gram-Positive Bacteria/genetics ; Metabolic Networks and Pathways/genetics ; Models, Molecular ; Periplasm/enzymology ; Periplasm/genetics ; Phylogeny ; Polysaccharides/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Sequence Alignment ; Sequence Homology, Amino Acid ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL.
Autorzy :
Sivinski J; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.
Ambrose AJ; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.
Panfilenko I; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.
Zerio CJ; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.
Machulis JM; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.
Mollasalehi N; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA.; Center for Innovation in Brain Science, Tucson, Arizona, USA.; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona, USA.
Kaneko LK; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.
Stevens M; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Ray AM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Park Y; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Wu C; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Hoang QQ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Johnson SM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Chapman E; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA .
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Źródło :
MBio [mBio] 2021 Jan 12; Vol. 12 (1). Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Chaperonin 10/*genetics
Chaperonin 60/*genetics
Escherichia coli/*genetics
Gram-Negative Bacteria/*genetics
Gram-Positive Bacteria/*genetics
Acinetobacter baumannii/drug effects ; Acinetobacter baumannii/genetics ; Acinetobacter baumannii/metabolism ; Anti-Bacterial Agents ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Chaperonin 10/chemistry ; Chaperonin 10/metabolism ; Chaperonin 60/chemistry ; Chaperonin 60/metabolism ; Enterobacter/drug effects ; Enterobacter/genetics ; Enterobacter/metabolism ; Enterococcus faecium/drug effects ; Enterococcus faecium/genetics ; Enterococcus faecium/metabolism ; Escherichia coli/drug effects ; Escherichia coli/metabolism ; Gene Knock-In Techniques ; Gene Knockout Techniques ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/metabolism ; Gram-Positive Bacteria/drug effects ; Gram-Positive Bacteria/metabolism ; Kinetics ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/metabolism ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/genetics ; Pseudomonas aeruginosa/metabolism ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/genetics ; Staphylococcus aureus/metabolism
Czasopismo naukowe
Tytuł :
A Crustin from Hydrothermal Vent Shrimp: Antimicrobial Activity and Mechanism.
Autorzy :
Wang Y; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China.; Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266237, China.; College of Earth and Planetary Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Zhang J; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China.; School of Ocean, Yantai University, Yantai 264005, China.
Sun Y; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China.; Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266237, China.
Sun L; CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China.; Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266237, China.; College of Earth and Planetary Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło :
Marine drugs [Mar Drugs] 2021 Mar 23; Vol. 19 (3). Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antimicrobial Cationic Peptides/*pharmacology
Gram-Positive Bacteria/*drug effects
Penaeidae/*metabolism
Amino Acid Sequence ; Animals ; Anti-Bacterial Agents/isolation & purification ; Antimicrobial Cationic Peptides/isolation & purification ; Conserved Sequence ; Gram-Positive Bacteria/growth & development ; Hydrogen-Ion Concentration ; Hydrothermal Vents ; Protein Domains ; Structure-Activity Relationship ; Temperature
Czasopismo naukowe
Tytuł :
Clinical outcomes of ceftobiprole in the treatment of acute bacterial skin and skin structure infections.
Autorzy :
Lee GM; Department of Nursing, Kaohsiung Municipal United Hospital, Taiwan.
Chao CM; Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan.
Lai CC; Department of Internal Medicine, Kaohsiung Veterans General Hospital, Tainan Branch, Tainan, Taiwan. Electronic address: .
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Źródło :
Journal of global antimicrobial resistance [J Glob Antimicrob Resist] 2021 Mar; Vol. 24, pp. 303-305. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Letter; Comment
MeSH Terms :
Cephalosporins*/therapeutic use
Gram-Positive Bacteria*
Opinia redakcyjna

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