Autor: "Grauer SM" - OpacWWW

Skocz do pozycji: 1.

Czasopismo naukowe

Skocz do pozycji: 2.

Tytuł:: MitoPark mice, an animal model of Parkinson's disease, show enhanced prepulse inhibition of acoustic startle and no loss of gating in response to the adenosine A(2A) antagonist SCH 412348.
Autorzy:: Grauer SM; Neuroscience Franchise, Merck Research Laboratories, 2015 Galloping Hill Road, K-15-C209, Kenilworth, NJ, 07033, USA, steven.grauer@merck.com.
Hodgson R
Hyde LA; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2014 Apr; Vol. 231 (7), pp. 1325-37. Date of Electronic Publication: 2013 Oct 23.
Typ publikacji:: Journal Article
MeSH Terms:: Disease Models, Animal*
Adenosine A2 Receptor Antagonists/*pharmacology
Parkinson Disease/*physiopathology
Prepulse Inhibition/*drug effects
Prepulse Inhibition/*physiology
Pyrimidines/*pharmacology
Triazoles/*pharmacology
Aging/physiology ; Animals ; Apomorphine/pharmacology ; Benzothiazoles/pharmacology ; Dopamine Agonists/pharmacology ; Male ; Mice ; Mice, Transgenic ; Motor Activity/drug effects ; Pramipexole

Czasopismo naukowe

Skocz do pozycji: 3.

Tytuł:: Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625.
Autorzy:: Marquis KL; Neuroscience Research Unit, Pfizer Global Research and Development, 445 Eastern Point Road, MS8220-4220, Groton, CT 06340, USA.
Comery TA
Jow F
Navarra RL
Grauer SM
Pulicicchio C
Kelley C
Brennan JA
Roncarati R
Scali C
Haydar S
Ghiron C
Terstappen GC
Dunlop J; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2011 Dec; Vol. 218 (4), pp. 635-47. Date of Electronic Publication: 2011 Jun 04.
Typ publikacji:: Journal Article
MeSH Terms:: Cognition Disorders/*drug therapy
Pyridines/*pharmacology
Risperidone/*pharmacology
Schizophrenia/*drug therapy
Urea/*analogs & derivatives
Animals ; Antipsychotic Agents/pharmacology ; Avoidance Learning/drug effects ; Cognition Disorders/etiology ; Drug Evaluation, Preclinical ; Drug Interactions ; Drug Therapy, Combination ; Male ; Memory/drug effects ; Mice ; Rats ; Rats, Long-Evans ; Rats, Sprague-Dawley ; Receptors, Nicotinic/drug effects ; Receptors, Nicotinic/metabolism ; Schizophrenia/physiopathology ; Urea/pharmacology ; alpha7 Nicotinic Acetylcholine Receptor

Czasopismo naukowe

Skocz do pozycji: 4.

Tytuł:: WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics.
Autorzy:: Grauer SM; Discovery Neuroscience, Wyeth Research, CN 8000, Princeton, NJ 08543, USA. />Graf R
Navarra R
Sung A
Logue SF
Stack G
Huselton C
Liu Z
Comery TA
Marquis KL
Rosenzweig-Lipson S; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2009 May; Vol. 204 (1), pp. 37-48. Date of Electronic Publication: 2008 Dec 20.
Typ publikacji:: Journal Article
MeSH Terms:: Serotonin 5-HT2 Receptor Agonists*
Antipsychotic Agents/*pharmacology
Avoidance Learning/*drug effects
Azepines/*pharmacology
Indoles/*pharmacology
Animals ; Antipsychotic Agents/adverse effects ; Antipsychotic Agents/therapeutic use ; Apomorphine/antagonists & inhibitors ; Azepines/adverse effects ; Azepines/therapeutic use ; Catalepsy/chemically induced ; Catalepsy/drug therapy ; Clozapine/adverse effects ; Clozapine/pharmacology ; Clozapine/therapeutic use ; Dizocilpine Maleate/pharmacology ; Drug Synergism ; Drug Therapy, Combination ; Haloperidol/adverse effects ; Haloperidol/pharmacology ; Haloperidol/therapeutic use ; Indoles/adverse effects ; Indoles/therapeutic use ; Male ; Mice ; Rats ; Rats, Sprague-Dawley ; Reflex, Startle/drug effects ; Stereotyped Behavior/drug effects

Czasopismo naukowe

Skocz do pozycji: 5.

Tytuł:: Intracerebral administration of metabotropic glutamate receptor agonists disrupts prepulse inhibition of acoustic startle in Sprague-Dawley rats.
Autorzy:: Grauer SM; Wyeth-Ayerst Research, Princeton, NJ 08543, USA.
Marquis KL; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 1999 Feb; Vol. 141 (4), pp. 405-12.
Typ publikacji:: Journal Article
MeSH Terms:: Acoustic Stimulation*
Inhibition, Psychological*
Nucleus Accumbens/*drug effects
Receptors, Metabotropic Glutamate/*agonists
Reflex, Startle/*drug effects
Amino Acids, Dicarboxylic/pharmacology ; Animals ; Cycloleucine/analogs & derivatives ; Cycloleucine/pharmacology ; Dopamine/metabolism ; Excitatory Amino Acid Agonists/pharmacology ; Glutamine/metabolism ; Male ; Neuroprotective Agents/pharmacology ; Nucleus Accumbens/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, Metabotropic Glutamate/antagonists & inhibitors ; Visual Cortex/drug effects ; Visual Cortex/metabolism

Czasopismo naukowe

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