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Wyświetlanie 1-11 z 11
Tytuł :
A phase 1 clinical trial of flavopiridol consolidation in chronic lymphocytic leukemia patients following chemoimmunotherapy.
Autorzy :
Awan FT; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA. .
Jones JA; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA.
Maddocks K; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA.
Poi M; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA.
Grever MR; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA.
Johnson A; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA.
Byrd JC; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA.
Andritsos LA; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA. .; Starling Loving Hall, 320 W. 10th Avenue, Columbus, Ohio, 43210, USA. .
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Źródło :
Annals of hematology [Ann Hematol] 2016 Jun; Vol. 95 (7), pp. 1137-43. Date of Electronic Publication: 2016 Apr 27.
Typ publikacji :
Clinical Trial; Clinical Trial, Phase I; Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Flavonoids/*therapeutic use
Immunotherapy/*trends
Leukemia, Lymphocytic, Chronic, B-Cell/*diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell/*drug therapy
Piperidines/*therapeutic use
Aged ; Disease-Free Survival ; Female ; Humans ; Immunotherapy/methods ; Male ; Middle Aged ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Phase I study of 5-aza-2'-deoxycytidine in combination with valproic acid in non-small-cell lung cancer.
Autorzy :
Chu BF; Division of Medical Oncology, Department of Medicine, College of Medicine and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Karpenko MJ
Liu Z
Aimiuwu J
Villalona-Calero MA
Chan KK
Grever MR
Otterson GA
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Źródło :
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2013 Jan; Vol. 71 (1), pp. 115-21. Date of Electronic Publication: 2012 Oct 09.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Neoplasms/*drug therapy
Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Azacitidine/administration & dosage ; Azacitidine/analogs & derivatives ; Carcinoma, Non-Small-Cell Lung/pathology ; Decitabine ; Dose-Response Relationship, Drug ; Drug Synergism ; Female ; Histone Deacetylase Inhibitors/administration & dosage ; Histone Deacetylase Inhibitors/adverse effects ; Histone Deacetylase Inhibitors/therapeutic use ; Humans ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Staging ; Treatment Outcome ; Valproic Acid/administration & dosage
Czasopismo naukowe
Tytuł :
Phase I and pharmacokinetic study of erlotinib (OSI-774) in combination with docetaxel in squamous cell carcinoma of the head and neck (SSCHN).
Autorzy :
Kraut EH; Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, College of Medicine and The Ohio State University Medical Center, Columbus, OH, USA. />Rhoades C
Zhang Y
Cheng H
Aimiumu J
Chen P
Lang J
Young DC
Agrawal A
Dancey J
Chan KK
Grever MR
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Źródło :
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2011 Mar; Vol. 67 (3), pp. 579-86. Date of Electronic Publication: 2010 May 19.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Carcinoma, Squamous Cell/*drug therapy
Head and Neck Neoplasms/*drug therapy
Administration, Oral ; Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics ; Area Under Curve ; Chromatography, Liquid ; Docetaxel ; Dose-Response Relationship, Drug ; Enzyme Induction/drug effects ; Erlotinib Hydrochloride ; Female ; Humans ; Male ; Maximum Tolerated Dose ; Middle Aged ; Quinazolines/administration & dosage ; Tandem Mass Spectrometry ; Taxoids/administration & dosage
Czasopismo naukowe
Tytuł :
A dose-finding and pharmacodynamic study of bortezomib in combination with weekly paclitaxel in patients with advanced solid tumors.
Autorzy :
Ramaswamy B; The Ohio State University, B401, Starling Loving Hall, 320 W 10th av, Columbus, OH 43210, USA. />Bekaii-Saab T
Schaaf LJ
Lesinski GB
Lucas DM
Young DC
Ruppert AS
Byrd JC
Culler K
Wilkins D
Wright JJ
Grever MR
Shapiro CL
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Źródło :
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2010 May; Vol. 66 (1), pp. 151-8. Date of Electronic Publication: 2009 Sep 23.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Boronic Acids/*administration & dosage
Neoplasm Metastasis/*drug therapy
Neoplasms/*drug therapy
Paclitaxel/*administration & dosage
Pyrazines/*administration & dosage
Adult ; Aged ; Boronic Acids/adverse effects ; Bortezomib ; Cytokines/blood ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Female ; Humans ; Male ; Maximum Tolerated Dose ; Middle Aged ; Neoplasms/blood ; Neoplasms/diagnosis ; Neutropenia/chemically induced ; Paclitaxel/adverse effects ; Proliferating Cell Nuclear Antigen/blood ; Proteasome Inhibitors ; Pyrazines/adverse effects ; Treatment Outcome ; bcl-2-Associated X Protein/blood
Czasopismo naukowe
Tytuł :
A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin's lymphoma.
Autorzy :
Willis CR; Sarah Cannon Research Institute, Nashville, TN 37203, USA. />Goodrich A
Park K
Waselenko JK
Lucas M
Reese A
Diehl LF
Grever MR
Byrd JC
Flinn IW
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Źródło :
Annals of hematology [Ann Hematol] 2006 May; Vol. 85 (5), pp. 301-7. Date of Electronic Publication: 2006 Mar 04.
Typ publikacji :
Clinical Trial, Phase II; Clinical Trial, Phase III; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Leukemia, Lymphocytic, Chronic, B-Cell/*drug therapy
Lymphoma, Non-Hodgkin/*drug therapy
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Chlorambucil/administration & dosage ; Chlorambucil/adverse effects ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/mortality ; Lymphoma, Non-Hodgkin/mortality ; Male ; Maximum Tolerated Dose ; Middle Aged ; Pentostatin/administration & dosage ; Pentostatin/adverse effects ; Recurrence ; Remission Induction ; Survival Rate ; Theophylline/administration & dosage ; Theophylline/adverse effects
Czasopismo naukowe
Tytuł :
G3139, a BCL-2 antisense oligo-nucleotide, in AML.
Autorzy :
Marcucci G; Division of Hematology-Oncology, Department of Medicine, The Ohio State University, Columbus, OH
Stock W
Dai G
Klisovic MI
Maharry K
Shen T
Liu S
Sher DA
Lucas D
Zwiebel A
Larson RA
Caligiuri MA
Bloomfield CD
Chan KK
Grever MR
Byrd JC
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Źródło :
Annals of hematology [Ann Hematol] 2004; Vol. 83 Suppl 1, pp. S93-4.
Typ publikacji :
Clinical Trial; Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Leukemia, Myeloid, Acute/*drug therapy
Thionucleotides/*adverse effects
Thionucleotides/*therapeutic use
Humans ; Leukemia, Myeloid, Acute/genetics ; Oligonucleotides, Antisense/adverse effects ; Oligonucleotides, Antisense/pharmacokinetics ; Oligonucleotides, Antisense/therapeutic use ; RNA, Messenger/drug effects ; RNA, Messenger/genetics ; Thionucleotides/pharmacokinetics
Czasopismo naukowe
Tytuł :
Biodistribution of O6-benzylguanine and its effectiveness against human brain tumor xenografts when given in polyethylene glycol or cremophor-EL.
Autorzy :
Dolan ME; Division of Hematology-Oncology, University of Chicago Medical Center, IL 60637.
Pegg AE
Moschel RC
Vishnuvajjala BR
Flora KP
Grever MR
Friedman HS
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Źródło :
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 1994; Vol. 35 (2), pp. 121-6.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Adjuvants, Pharmaceutic/*administration & dosage
Antineoplastic Agents/*pharmacokinetics
Glioblastoma/*drug therapy
Glycerol/*analogs & derivatives
Guanine/*analogs & derivatives
Polyethylene Glycols/*administration & dosage
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/therapeutic use ; Carmustine/administration & dosage ; Child ; Chromatography, High Pressure Liquid ; Female ; Glioblastoma/metabolism ; Glioblastoma/mortality ; Glycerol/administration & dosage ; Guanine/administration & dosage ; Guanine/pharmacokinetics ; Guanine/therapeutic use ; Humans ; Injections, Intraperitoneal ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Transplantation ; Solubility ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Fludarabine monophosphate: a potentially useful agent in chronic lymphocytic leukemia.
Autorzy :
Grever MR; Ohio State University, Division of Hematology/Oncology, Columbus 43210.
Kopecky KJ
Coltman CA
Files JC
Greenberg BR
Hutton JJ
Talley R
Von Hoff DD
Balcerzak SP
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Źródło :
Nouvelle revue francaise d'hematologie [Nouv Rev Fr Hematol] 1988; Vol. 30 (5-6), pp. 457-9.
Typ publikacji :
Journal Article
MeSH Terms :
Antimetabolites, Antineoplastic/*therapeutic use
Arabinonucleotides/*therapeutic use
Leukemia, Lymphocytic, Chronic, B-Cell/*drug therapy
Vidarabine Phosphate/*therapeutic use
Adult ; Aged ; Antimetabolites, Antineoplastic/adverse effects ; Bone Marrow/drug effects ; Drug Evaluation ; Humans ; Middle Aged ; Remission Induction ; Vidarabine Phosphate/adverse effects ; Vidarabine Phosphate/analogs & derivatives
Czasopismo naukowe
    Wyświetlanie 1-11 z 11

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