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Tytuł:
Improvement of non-invasive tests of liver steatosis and fibrosis as indicators for non-alcoholic fatty liver disease in type 2 diabetes mellitus patients with elevated cardiovascular risk profile using the PPAR-α/γ agonist aleglitazar.
Autorzy:
Grobbee EJ; Department of Gastroenterology and Hepatology, Erasmus MC Medical Center, Rotterdam, The Netherlands.
de Jong VD; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Julius Clinical, Zeist, The Netherlands.
Schrieks IC; Julius Clinical, Zeist, The Netherlands.
Tushuizen ME; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands.
Holleboom AG; Department of Vascular Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Tardif JC; Montreal Heart Institute Coordinating Center, Université de Montréal, Montreal, Canada.
Lincoff AM; Department of Cardiovascular Medicine, Cleveland Clinic Coordinating Center for Clinical Research (C5Research), Cleveland, OH, United States of America.
Schwartz GG; Division of Cardiology, VA Medical Center and University of Colorado School of Medicine, Denver, CO, United States of America.
Castro Cabezas M; Julius Clinical, Zeist, The Netherlands.; Department of Internal Medicine, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands.; Department of Endocrinology, Erasmus MC Medical Center, Rotterdam, The Netherlands.
Grobbee DE; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Julius Clinical, Zeist, The Netherlands.
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Źródło:
PloS one [PLoS One] 2022 Nov 15; Vol. 17 (11), pp. e0277706. Date of Electronic Publication: 2022 Nov 15 (Print Publication: 2022).
Typ publikacji:
Randomized Controlled Trial; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/complications
Non-alcoholic Fatty Liver Disease*/diagnosis
Non-alcoholic Fatty Liver Disease*/drug therapy
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/metabolism
Cardiovascular Diseases*/metabolism
Humans ; PPAR alpha/metabolism ; PPAR gamma/metabolism ; Risk Factors ; Hypoglycemic Agents/therapeutic use ; Liver/metabolism ; Liver Cirrhosis/complications ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/drug therapy ; Heart Disease Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cardiovascular disease risk in an urban African population: a cross-sectional analysis on the role of HIV and antiretroviral treatment.
Autorzy:
Vos AG; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands. .; Department of Internal Medicine & Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands. .; Ezintsha, Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa. .
Hoeve K; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
Barth RE; Department of Internal Medicine & Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands.
Peper J; Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Moorhouse M; Ezintsha, Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Crowther NJ; Department of Chemical Pathology, National Health Laboratory Service and University of the Witwatersrand, Johannesburg, South Africa.
Venter WDF; Ezintsha, Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Grobbee DE; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
Bots ML; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
Klipstein-Grobusch K; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.; Division of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
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Źródło:
Retrovirology [Retrovirology] 2019 Dec 03; Vol. 16 (1), pp. 37. Date of Electronic Publication: 2019 Dec 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Retroviral Agents/*therapeutic use
Cardiovascular Diseases/*epidemiology
HIV Infections/*drug therapy
HIV Infections/*epidemiology
Urban Population/*statistics & numerical data
Adult ; Cardiovascular Diseases/virology ; Carotid Intima-Media Thickness ; Cross-Sectional Studies ; Female ; HIV Infections/complications ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Risk Factors ; South Africa/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effect of computerized decision support systems on cardiovascular risk factors: a systematic review and meta-analysis.
Autorzy:
Groenhof TKJ; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, the Netherlands. .
Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Health Data Research UK and Institute of Health Informatics, University College London, London, UK.
Groenwold RHH; Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, UK.; Department of Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Grobbee DE; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, the Netherlands.
Visseren FLJ; Department of Vascular Medicine, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, the Netherlands.
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Corporate Authors:
UCC-SMART study group
Źródło:
BMC medical informatics and decision making [BMC Med Inform Decis Mak] 2019 Jun 10; Vol. 19 (1), pp. 108. Date of Electronic Publication: 2019 Jun 10.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:
Cardiovascular Diseases*
Decision Support Systems, Clinical*/statistics & numerical data
Medical Informatics Applications*
Risk Management*/statistics & numerical data
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lipid levels, insulin resistance and cardiovascular risk over 96 weeks of antiretroviral therapy: a randomised controlled trial comparing low-dose stavudine and tenofovir.
Autorzy:
Vos AG; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa. .; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. .; Department of Internal Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. .
Chersich MF; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Klipstein-Grobusch K; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Division of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Zuithoff P; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Moorhouse MA; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Lalla-Edward ST; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Kambugu A; Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Kumarasamy N; YRGCARE Medical Centre, CART Clinical Research Site, Voluntary Health Services, Chennai, India.
Grobbee DE; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Barth RE; Department of Internal Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Venter WD; Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
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Źródło:
Retrovirology [Retrovirology] 2018 Dec 14; Vol. 15 (1), pp. 77. Date of Electronic Publication: 2018 Dec 14.
Typ publikacji:
Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin Resistance*
Antiretroviral Therapy, Highly Active/*adverse effects
Cardiovascular Diseases/*diagnosis
HIV Infections/*drug therapy
Lipids/*blood
Stavudine/*therapeutic use
Tenofovir/*therapeutic use
Adult ; Anti-HIV Agents/administration & dosage ; Anti-HIV Agents/therapeutic use ; Blood Glucose ; Cardiovascular Diseases/etiology ; Double-Blind Method ; Female ; HIV Infections/complications ; HIV-1/drug effects ; Humans ; India ; Male ; Risk Factors ; South Africa ; Stavudine/administration & dosage ; Tenofovir/administration & dosage ; Uganda
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Knowledge and awareness of and perception towards cardiovascular disease risk in sub-Saharan Africa: A systematic review.
Autorzy:
Boateng D; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Wekesah F; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; African Population and Health Research Center, Nairobi, Kenya.
Browne JL; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Agyemang C; Department of Public Health, Academic Medical Center, University of Amsterdam, Amsterdam Public Health Institute, Amsterdam, The Netherlands.
Agyei-Baffour P; School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Aikins AD; Regional Institute for Population Studies, University of Ghana, Legon, Ghana.
Smit HA; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Grobbee DE; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Klipstein-Grobusch K; Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Division of Epidemiology & Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
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Źródło:
PloS one [PLoS One] 2017 Dec 12; Vol. 12 (12), pp. e0189264. Date of Electronic Publication: 2017 Dec 12 (Print Publication: 2017).
Typ publikacji:
Journal Article; Review; Systematic Review
MeSH Terms:
Awareness*
Knowledge*
Cardiovascular Diseases/*epidemiology
Africa South of the Sahara/epidemiology ; Alcohol Drinking ; Cardiovascular Diseases/complications ; Diabetes Complications ; Humans ; Hypertension/complications ; Risk Factors ; Sedentary Behavior ; Smoking ; Stress, Psychological
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Clustering of cardiovascular risk factors and carotid intima-media thickness: The USE-IMT study.
Autorzy:
Wang X; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht,Utrecht, the Netherlands.
Dalmeijer GW; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht,Utrecht, the Netherlands.
den Ruijter HM; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Anderson TJ; Department of Cardiac Sciences and Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada.
Britton AR; Department of Epidemiology and Public Health University College London, London, United Kingdom.
Dekker J; Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.
Engström G; Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Evans GW; Department of Biostatistical Sciences and Neurology, Wake Forest School of Medicine, Winston-Salem, NC, United States of America.
de Graaf J; Department of General Internal Medicine, Division of Vascular Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Grobbee DE; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht,Utrecht, the Netherlands.; University of Malaya Medical Center, Kuala Lumpur, Malaysia.
Hedblad B; Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Holewijn S; Department of General Internal Medicine, Division of Vascular Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Ikeda A; Osaka Medical Center for Health Science and Promotion, Osaka, Japan.
Kauhanen J; The Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
Kitagawa K; Department of Neurology, Tokyo Women Medical University, Tokyo, Japan.
Kitamura A; Osaka Medical Center for Health Science and Promotion, Osaka, Japan.
Kurl S; The Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
Lonn EM; Department of Medicine, Division of Cardiology and Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Lorenz MW; Department of Neurology, University Hospital, Goethe-University, Frankfurt am Main, Germany.; Department of Neurology, Krankenhaus Nordwest, Frankfurt am Main, Germany.
Mathiesen EB; Brain and Circulation Research Group, Department of Clinical Medicine, University of Tromsö, Tromsö, Norway.
Nijpels G; Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.
Okazaki S; Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan.
Polak JF; Department of Radiology, Tufts University School of Medicine, Boston, United States of America.
Price JF; Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Rembold CM; Cardiology Division, Department of Internal Medicine, University of Virginia, Charlottesville, VA, United States of America.
Rosvall M; Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Rundek T; Department of Neurology, Miller School of Medicine, University of Miami, Miami, Fl, United States of America.
Salonen JT; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; MAS-Metabolic Analytical Services Oy, Helsinki, Finland.
Sitzer M; Department of Neurology, University Hospital, Goethe-University, Frankfurt am Main, Germany and Department of Neurology Klinikum Herford, Germany.
Stehouwer CD; Department of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.
Tuomainen TP; The Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
Peters SA; The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht,Utrecht, the Netherlands.
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Źródło:
PloS one [PLoS One] 2017 Mar 21; Vol. 12 (3), pp. e0173393. Date of Electronic Publication: 2017 Mar 21 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Carotid Intima-Media Thickness*
Cardiovascular Diseases/*diagnostic imaging
Cardiovascular Diseases/*epidemiology
Age Factors ; Aged ; Cholesterol/blood ; Cluster Analysis ; Cohort Studies ; Cross-Sectional Studies ; Female ; Humans ; Hypertension/diagnostic imaging ; Hypertension/epidemiology ; Linear Models ; Male ; Meta-Analysis as Topic ; Middle Aged ; Overweight/diagnostic imaging ; Overweight/epidemiology ; Risk Factors ; Sex Factors ; Smoking/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Association between Immune Markers and Surrogate Markers of Cardiovascular Disease in HIV Positive Patients: A Systematic Review.
Autorzy:
Vos AG; Julius Global Health, The Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Internal Medicine & Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands.; School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Hulzebosch A; Julius Global Health, The Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Grobbee DE; Julius Global Health, The Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Barth RE; Department of Internal Medicine & Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands.
Klipstein-Grobusch K; Julius Global Health, The Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Division of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
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Źródło:
PloS one [PLoS One] 2017 Jan 13; Vol. 12 (1), pp. e0169986. Date of Electronic Publication: 2017 Jan 13 (Print Publication: 2017).
Typ publikacji:
Journal Article; Review; Systematic Review
MeSH Terms:
Biomarkers/*metabolism
Cardiovascular Diseases/*diagnosis
HIV Infections/*complications
HIV-1/*pathogenicity
Cardiovascular Diseases/etiology ; Cardiovascular Diseases/metabolism ; HIV Infections/virology ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Automatic Coronary Artery Calcium Scoring on Radiotherapy Planning CT Scans of Breast Cancer Patients: Reproducibility and Association with Traditional Cardiovascular Risk Factors.
Autorzy:
Gernaat SA; Department of Epidemiology, Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Išgum I; Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
de Vos BD; Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
Takx RA; Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Young-Afat DA; Department of Epidemiology, Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Rijnberg N; Devision of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Grobbee DE; Department of Epidemiology, Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands.
van der Graaf Y; Department of Epidemiology, Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands.
de Jong PA; Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Leiner T; Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
van den Bongard DH; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
Pignol JP; Department of Radiation Oncology, Erasmus Medical Center, Rotterdam, The Netherlands.
Verkooijen HM; Imaging Division, University Medical Center Utrecht, Utrecht, The Netherlands.
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Źródło:
PloS one [PLoS One] 2016 Dec 09; Vol. 11 (12), pp. e0167925. Date of Electronic Publication: 2016 Dec 09 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Automation*
Breast Neoplasms/*radiotherapy
Calcium/*metabolism
Cardiovascular Diseases/*metabolism
Coronary Vessels/*pathology
Aged ; Algorithms ; Cohort Studies ; Coronary Vessels/metabolism ; Female ; Humans ; Middle Aged ; Patient Care Planning ; Reproducibility of Results ; Risk Factors ; Tomography, X-Ray Computed
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Pro-Inflammatory Markers in Relation to Cardiovascular Disease in HIV Infection. A Systematic Review.
Autorzy:
Vos AG; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands.
Idris NS; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Barth RE; Department of Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands.
Klipstein-Grobusch K; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Grobbee DE; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
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Źródło:
PloS one [PLoS One] 2016 Jan 25; Vol. 11 (1), pp. e0147484. Date of Electronic Publication: 2016 Jan 25 (Print Publication: 2016).
Typ publikacji:
Journal Article; Review; Systematic Review
MeSH Terms:
Biomarkers/*metabolism
Cardiovascular Diseases/*complications
HIV Infections/*complications
Inflammation/*metabolism
Cardiovascular Diseases/metabolism ; Carotid Arteries/pathology ; HIV Infections/metabolism ; Humans ; Prognosis ; Tunica Intima/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A novel approach for establishing cardiovascular drug efficacy.
Autorzy:
Heerspink HJ; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, the Netherlands.
Grobbee DE; Julius Center for Health Science and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
de Zeeuw D; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, the Netherlands.
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Źródło:
Nature reviews. Drug discovery [Nat Rev Drug Discov] 2014 Dec; Vol. 13 (12), pp. 942. Date of Electronic Publication: 2014 Nov 14.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Cardiovascular Agents/*administration & dosage
Cardiovascular Diseases/*drug therapy
Drug Delivery Systems/*trends
Animals ; Cardiovascular Diseases/diagnosis ; Clinical Trials as Topic/trends ; Humans ; Treatment Outcome
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Autorzy:
Ehret GB
Munroe PB
Rice KM
Bochud M
Johnson AD
Chasman DI
Smith AV
Tobin MD
Verwoert GC
Hwang SJ
Pihur V
Vollenweider P
O'Reilly PF
Amin N
Bragg-Gresham JL
Teumer A
Glazer NL
Launer L
Zhao JH
Aulchenko Y
Heath S
Sõber S
Parsa A
Luan J
Arora P
Dehghan A
Zhang F
Lucas G
Hicks AA
Jackson AU
Peden JF
Tanaka T
Wild SH
Rudan I
Igl W
Milaneschi Y
Parker AN
Fava C
Chambers JC
Fox ER
Kumari M
Go MJ
van der Harst P
Kao WH
Sjögren M
Vinay DG
Alexander M
Tabara Y
Shaw-Hawkins S
Whincup PH
Liu Y
Shi G
Kuusisto J
Tayo B
Seielstad M
Sim X
Nguyen KD
Lehtimäki T
Matullo G
Wu Y
Gaunt TR
Onland-Moret NC
Cooper MN
Platou CG
Org E
Hardy R
Dahgam S
Palmen J
Vitart V
Braund PS
Kuznetsova T
Uiterwaal CS
Adeyemo A
Palmas W
Campbell H
Ludwig B
Tomaszewski M
Tzoulaki I
Palmer ND
Aspelund T
Garcia M
Chang YP
O'Connell JR
Steinle NI
Grobbee DE
Arking DE
Kardia SL
Morrison AC
Hernandez D
Najjar S
McArdle WL
Hadley D
Brown MJ
Connell JM
Hingorani AD
Day IN
Lawlor DA
Beilby JP
Lawrence RW
Clarke R
Hopewell JC
Ongen H
Dreisbach AW
Li Y
Young JH
Bis JC
Kähönen M
Viikari J
Adair LS
Lee NR
Chen MH
Olden M
Pattaro C
Bolton JA
Köttgen A
Bergmann S
Mooser V
Chaturvedi N
Frayling TM
Islam M
Jafar TH
Erdmann J
Kulkarni SR
Bornstein SR
Grässler J
Groop L
Voight BF
Kettunen J
Howard P
Taylor A
Guarrera S
Ricceri F
Emilsson V
Plump A
Barroso I
Khaw KT
Weder AB
Hunt SC
Sun YV
Bergman RN
Collins FS
Bonnycastle LL
Scott LJ
Stringham HM
Peltonen L
Perola M
Vartiainen E
Brand SM
Staessen JA
Wang TJ
Burton PR
Soler Artigas M
Dong Y
Snieder H
Wang X
Zhu H
Lohman KK
Rudock ME
Heckbert SR
Smith NL
Wiggins KL
Doumatey A
Shriner D
Veldre G
Viigimaa M
Kinra S
Prabhakaran D
Tripathy V
Langefeld CD
Rosengren A
Thelle DS
Corsi AM
Singleton A
Forrester T
Hilton G
McKenzie CA
Salako T
Iwai N
Kita Y
Ogihara T
Ohkubo T
Okamura T
Ueshima H
Umemura S
Eyheramendy S
Meitinger T
Wichmann HE
Cho YS
Kim HL
Lee JY
Scott J
Sehmi JS
Zhang W
Hedblad B
Nilsson P
Smith GD
Wong A
Narisu N
Stančáková A
Raffel LJ
Yao J
Kathiresan S
O'Donnell CJ
Schwartz SM
Ikram MA
Longstreth WT Jr
Mosley TH
Seshadri S
Shrine NR
Wain LV
Morken MA
Swift AJ
Laitinen J
Prokopenko I
Zitting P
Cooper JA
Humphries SE
Danesh J
Rasheed A
Goel A
Hamsten A
Watkins H
Bakker SJ
van Gilst WH
Janipalli CS
Mani KR
Yajnik CS
Hofman A
Mattace-Raso FU
Oostra BA
Demirkan A
Isaacs A
Rivadeneira F
Lakatta EG
Orru M
Scuteri A
Ala-Korpela M
Kangas AJ
Lyytikäinen LP
Soininen P
Tukiainen T
Würtz P
Ong RT
Dörr M
Kroemer HK
Völker U
Völzke H
Galan P
Hercberg S
Lathrop M
Zelenika D
Deloukas P
Mangino M
Spector TD
Zhai G
Meschia JF
Nalls MA
Sharma P
Terzic J
Kumar MV
Denniff M
Zukowska-Szczechowska E
Wagenknecht LE
Fowkes FG
Charchar FJ
Schwarz PE
Hayward C
Guo X
Rotimi C
Bots ML
Brand E
Samani NJ
Polasek O
Talmud PJ
Nyberg F
Kuh D
Laan M
Hveem K
Palmer LJ
van der Schouw YT
Casas JP
Mohlke KL
Vineis P
Raitakari O
Ganesh SK
Wong TY
Tai ES
Cooper RS
Laakso M
Rao DC
Harris TB
Morris RW
Dominiczak AF
Kivimaki M
Marmot MG
Miki T
Saleheen D
Chandak GR
Coresh J
Navis G
Salomaa V
Han BG
Zhu X
Kooner JS
Melander O
Ridker PM
Bandinelli S
Gyllensten UB
Wright AF
Wilson JF
Ferrucci L
Farrall M
Tuomilehto J
Pramstaller PP
Elosua R
Soranzo N
Sijbrands EJ
Altshuler D
Loos RJ
Shuldiner AR
Gieger C
Meneton P
Uitterlinden AG
Wareham NJ
Gudnason V
Rotter JI
Rettig R
Uda M
Strachan DP
Witteman JC
Hartikainen AL
Beckmann JS
Boerwinkle E
Vasan RS
Boehnke M
Larson MG
Järvelin MR
Psaty BM
Abecasis GR
Chakravarti A
Elliott P
van Duijn CM
Newton-Cheh C
Levy D
Caulfield MJ
Johnson T
Pokaż więcej
Corporate Authors:
International Consortium for Blood Pressure Genome-Wide Association Studies
CARDIoGRAM consortium
CKDGen Consortium
KidneyGen Consortium
EchoGen consortium
CHARGE-HF consortium
Źródło:
Nature [Nature] 2011 Sep 11; Vol. 478 (7367), pp. 103-9. Date of Electronic Publication: 2011 Sep 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Blood Pressure/*genetics
Cardiovascular Diseases/*genetics
Genetic Predisposition to Disease/*genetics
Polymorphism, Single Nucleotide/*genetics
Africa/ethnology ; Asia/ethnology ; Blood Pressure/physiology ; Coronary Artery Disease/genetics ; Europe/ethnology ; Genome-Wide Association Study ; Humans ; Hypertension/genetics ; Kidney Diseases/genetics ; Stroke/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
An international randomised placebo-controlled trial of a four-component combination pill ("polypill") in people with raised cardiovascular risk.
Autorzy:
Rodgers A
Patel A
Berwanger O
Bots M
Grimm R
Grobbee DE
Jackson R
Neal B
Neaton J
Poulter N
Rafter N
Raju PK
Reddy S
Thom S
Vander Hoorn S
Webster R
Pokaż więcej
Corporate Authors:
PILL Collaborative Group
Źródło:
PloS one [PLoS One] 2011; Vol. 6 (5), pp. e19857. Date of Electronic Publication: 2011 May 25.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Internationality*
Cardiovascular Agents/*administration & dosage
Cardiovascular Agents/*pharmacology
Cardiovascular Diseases/*prevention & control
Adolescent ; Adult ; Aged ; Blood Pressure/drug effects ; Cardiovascular Agents/adverse effects ; Cardiovascular Diseases/metabolism ; Cardiovascular Diseases/physiopathology ; Cholesterol/metabolism ; Drug Combinations ; Female ; Humans ; Male ; Middle Aged ; Placebos ; Risk ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cardiovascular risk factor assessment after pre-eclampsia in primary care.
Autorzy:
Nijdam ME; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands. />Timmerman MR
Franx A
Bruinse HW
Numans ME
Grobbee DE
Bots ML
Pokaż więcej
Źródło:
BMC family practice [BMC Fam Pract] 2009 Dec 08; Vol. 10, pp. 77. Date of Electronic Publication: 2009 Dec 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pre-Eclampsia*
Risk Assessment*
Blood Pressure Determination/*statistics & numerical data
Cardiovascular Diseases/*diagnosis
Primary Health Care/*methods
Adult ; Female ; Follow-Up Studies ; Humans ; Hypertension/diagnosis ; Netherlands ; Pregnancy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Genome-wide association study identifies eight loci associated with blood pressure.
Autorzy:
Newton-Cheh C; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. />Johnson T
Gateva V
Tobin MD
Bochud M
Coin L
Najjar SS
Zhao JH
Heath SC
Eyheramendy S
Papadakis K
Voight BF
Scott LJ
Zhang F
Farrall M
Tanaka T
Wallace C
Chambers JC
Khaw KT
Nilsson P
van der Harst P
Polidoro S
Grobbee DE
Onland-Moret NC
Bots ML
Wain LV
Elliott KS
Teumer A
Luan J
Lucas G
Kuusisto J
Burton PR
Hadley D
McArdle WL
Brown M
Dominiczak A
Newhouse SJ
Samani NJ
Webster J
Zeggini E
Beckmann JS
Bergmann S
Lim N
Song K
Vollenweider P
Waeber G
Waterworth DM
Yuan X
Groop L
Orho-Melander M
Allione A
Di Gregorio A
Guarrera S
Panico S
Ricceri F
Romanazzi V
Sacerdote C
Vineis P
Barroso I
Sandhu MS
Luben RN
Crawford GJ
Jousilahti P
Perola M
Boehnke M
Bonnycastle LL
Collins FS
Jackson AU
Mohlke KL
Stringham HM
Valle TT
Willer CJ
Bergman RN
Morken MA
Döring A
Gieger C
Illig T
Meitinger T
Org E
Pfeufer A
Wichmann HE
Kathiresan S
Marrugat J
O'Donnell CJ
Schwartz SM
Siscovick DS
Subirana I
Freimer NB
Hartikainen AL
McCarthy MI
O'Reilly PF
Peltonen L
Pouta A
de Jong PE
Snieder H
van Gilst WH
Clarke R
Goel A
Hamsten A
Peden JF
Seedorf U
Syvänen AC
Tognoni G
Lakatta EG
Sanna S
Scheet P
Schlessinger D
Scuteri A
Dörr M
Ernst F
Felix SB
Homuth G
Lorbeer R
Reffelmann T
Rettig R
Völker U
Galan P
Gut IG
Hercberg S
Lathrop GM
Zelenika D
Deloukas P
Soranzo N
Williams FM
Zhai G
Salomaa V
Laakso M
Elosua R
Forouhi NG
Völzke H
Uiterwaal CS
van der Schouw YT
Numans ME
Matullo G
Navis G
Berglund G
Bingham SA
Kooner JS
Connell JM
Bandinelli S
Ferrucci L
Watkins H
Spector TD
Tuomilehto J
Altshuler D
Strachan DP
Laan M
Meneton P
Wareham NJ
Uda M
Jarvelin MR
Mooser V
Melander O
Loos RJ
Elliott P
Abecasis GR
Caulfield M
Munroe PB
Pokaż więcej
Corporate Authors:
Wellcome Trust Case Control Consortium
Źródło:
Nature genetics [Nat Genet] 2009 Jun; Vol. 41 (6), pp. 666-76. Date of Electronic Publication: 2009 May 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Genome-Wide Association Study*
Polymorphism, Single Nucleotide*
Blood Pressure/*genetics
Cardiovascular Diseases/*genetics
Adaptor Proteins, Signal Transducing ; Cardiovascular Diseases/physiopathology ; Chromosome Mapping ; Cytochrome P-450 CYP1A2/genetics ; DNA-Binding Proteins/genetics ; Diastole/genetics ; Europe ; Fibroblast Growth Factor 5/genetics ; Genetic Variation ; Humans ; India ; Intracellular Signaling Peptides and Proteins ; Methylenetetrahydrofolate Reductase (NADPH2)/genetics ; Open Reading Frames/genetics ; Phospholipase C delta/genetics ; Proteins/genetics ; Steroid 17-alpha-Hydroxylase/genetics ; Systole/genetics ; White People/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evaluation of nonalcoholic fatty liver disease (NAFLD) in severe obesity using noninvasive tests and imaging techniques.
Autorzy:
Theel, Willy
Boxma‐de Klerk, Bianca M.
Dirksmeier‐Harinck, Femme
van Rossum, Elisabeth F. C.
Kanhai, Danny A.
Apers, Jan
van Dalen, Bas M.
de Knegt, Robert J.
Holleboom, Anthony G.
Tushuizen, Maarten E.
Grobbee, Diederick E.
Wiebolt, Janneke
Castro Cabezas, Manuel
Pokaż więcej
Temat:
NON-alcoholic fatty liver disease
FATTY liver
TYPE 2 diabetes
HEPATIC fibrosis
CARDIOVASCULAR diseases
OBESITY
Źródło:
Obesity Reviews; Aug2022, Vol. 23 Issue 8, p1-18, 18p
Czasopismo naukowe
Szczegóły
Tytuł:
Patterns of Immune Activation in HIV and Non HIV Subjects and Its Relation to Cardiovascular Disease Risk.
Autorzy:
Vos, Alinda G.
Dodd, Caitlin N.
Delemarre, Eveline M.
Nierkens, Stefan
Serenata, Celicia
Grobbee, Diederick E.
Klipstein-Grobusch, Kerstin
Venter, W. D. Francois
Pokaż więcej
Temat:
CARDIOVASCULAR diseases
HIV infections
HIV
BIOMARKERS
PRINCIPAL components analysis
Źródło:
Frontiers in Immunology; 7/5/2021, Vol. 12, p1-9, 9p
Terminy geograficzne:
JOHANNESBURG (South Africa)
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 64

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