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Wyświetlanie 1-11 z 11
Tytuł :
Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma.
Autorzy :
Lin SH; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Sampson JN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Ludwig Maximilians Universität (LMU), Munich, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Surdez D; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.
Reynaud S; SIREDO Oncology Centre, Institut Curie, Paris, France.
Mirabeau O; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France.
Karlins E; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America.
Rubio RA; Max-Eder Research Group for Pediatric Sarcoma Biology, Ludwig Maximilians Universität (LMU), Munich, Germany.
Zaidi S; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France.
Grossetête-Lalami S; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France.
Ballet S; SIREDO Oncology Centre, Institut Curie, Paris, France.
Lapouble E; SIREDO Oncology Centre, Institut Curie, Paris, France.
Laurence V; SIREDO Oncology Centre, Institut Curie, Paris, France.
Michon J; SIREDO Oncology Centre, Institut Curie, Paris, France.
Pierron G; SIREDO Oncology Centre, Institut Curie, Paris, France.
Kovar H; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria.
Kontny U; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Uniklinik RWTH Aachen, Aachen, Germany.
González-Neira A; Human Genotyping Unit-CeGen, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Madrid, Spain.
Alonso J; Unidad de Tumores Solidos Infantiles (IIER-ISCIII) & Centro de Investigación Biomédica en Red de Enfermedades Raras (CB06/07/1009; CIBERER-ISCIII), Instituto de Salud Carlos III, Majadahonda, Spain.
Patino-Garcia A; Laboratory of Pediatrics, University Clinic of Navarra, Program in Solid Tumors, Center for Applied Medical Research (CIMA) and Navarra's Health Research Institute (IdiSNA), Pamplona, Spain.
Corradini N; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, Lyon, France.
Bérard PM; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, Lyon, France.
Miller J; Information Management Services, Inc., Calverton, MD, United States of America.
Freedman ND; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Rothman N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Carter BD; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, United States of America.
Dagnall CL; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America.
Burdett L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America.
Jones K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America.
Manning M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America.
Wyatt K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America.
Zhou W; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America.
Yeager M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America.
Cox DG; Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.
Hoover RN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Khan J; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States of America.
Armstrong GT; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
Leisenring WM; Cancer Prevention and Clinical Statistics Programs, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Bhatia S; Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Robison LL; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
Kulozik AE; Department of Pediatric Oncology, Hematology and Immunology and Hopp Children Cancer Center, University of Heidelberg, Heidelberg, Germany.
Kriebel J; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), München, Neuherberg, Germany.
Meitinger T; German Research Center for Environmental Health, Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany.
Metzler M; Department of Paediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany.
Krumbholz M; Department of Paediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany.
Hartmann W; Division of Translational Pathology, Gerhard-Domagk Institute of Pathology, University Hospital of Münster, Münster, Germany.
Strauch K; Institute of Genetic Epidemiology, LMU Munich, Munich, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Dirksen U; Pediatrics III, West German Cancer Centre, University Hospital Essen, Essen, Germany.; German Cancer Consortium (DKTK), Center Essen, Heidelberg, Germany.
Mirabello L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Tucker MA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Tirode F; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France.
Morton LM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
Delattre O; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France.
Machiela MJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Sep 03; Vol. 15 (9), pp. e0237792. Date of Electronic Publication: 2020 Sep 03 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Loci*
Genetic Predisposition to Disease*
Genetic Variation*
Germ Cells/*metabolism
Sarcoma, Ewing/*genetics
Genome-Wide Association Study ; Humans ; Linkage Disequilibrium/genetics ; Odds Ratio ; Polymorphism, Single Nucleotide/genetics
Czasopismo naukowe
Tytuł :
Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors.
Autorzy :
Leruste A; PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Tosello J; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Ramos RN; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Tauziède-Espariat A; Sainte-Anne Hospital, Department of Neuropathology, Paris, France.
Brohard S; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Han ZY; PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Beccaria K; AP-HP, Necker Hospital, Department of Neurosurgery, Paris, France.
Andrianteranagna M; PSL Research University, Institut Curie Research Center, INSERM U900, Paris, France; MINES ParisTech, PSL Research University, CBIO-Centre for Computational Biology, Paris, France.
Caudana P; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Nikolic J; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Chauvin C; PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Niborski LL; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Manriquez V; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Richer W; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Masliah-Planchon J; PSL Research University, Institut Curie Hospital, Laboratory of Somatic Genetics, Paris, France.
Grossetête-Lalami S; PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Bohec M; PSL Research University, Institut Curie Genomics of Excellence (ICGex) Platform, Paris, France.
Lameiras S; PSL Research University, Institut Curie Genomics of Excellence (ICGex) Platform, Paris, France.
Baulande S; PSL Research University, Institut Curie Genomics of Excellence (ICGex) Platform, Paris, France.
Pouponnot C; PSL Research University, Institut Curie Research Center, CNRS UMR 3347, INSERM U1021, Orsay, France.
Coulomb A; AP-HP, Armand Trousseau Hospital, Department of Pathology, Paris, France.
Galmiche L; AP-HP, Necker Hospital, Department of Pathology, Paris, France.
Surdez D; PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Servant N; PSL Research University, Institut Curie Research Center, INSERM U900, Paris, France; MINES ParisTech, PSL Research University, CBIO-Centre for Computational Biology, Paris, France.
Helft J; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Sedlik C; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Puget S; AP-HP, Necker Hospital, Department of Neurosurgery, Paris, France.
Benaroch P; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France.
Delattre O; PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Waterfall JJ; PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France. Electronic address: .
Piaggio E; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; PSL Research University, Institut Curie Research Center, INSERM U932, Paris, France. Electronic address: .
Bourdeaut F; PSL Research University, Institut Curie Research Center, INSERM U830, Paris, France; PSL Research University, Institut Curie Research Center, Translational Research Department, Paris, France; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2019 Dec 09; Vol. 36 (6), pp. 597-612.e8. Date of Electronic Publication: 2019 Nov 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromatin Assembly and Disassembly/*immunology
Rhabdoid Tumor/*genetics
Rhabdoid Tumor/*immunology
T-Lymphocytes/*immunology
Animals ; Chromosomal Proteins, Non-Histone/genetics ; Chromosomal Proteins, Non-Histone/immunology ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/immunology ; Humans ; Immunohistochemistry/methods ; Mice, Inbred C57BL ; Mice, Transgenic ; Mutation/genetics ; Nuclear Proteins/genetics ; Transcription Factors/genetics ; Transcription Factors/immunology
Czasopismo naukowe
Tytuł :
Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility.
Autorzy :
Machiela MJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU, 80337, Munich, Germany.; German Consortium for Cancer Research (DKTK), 69120, Heidelberg, Germany.; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Surdez D; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
Reynaud S; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.; Unité de Génétique Somatique, Institut Curie, Centre Hospitalier, 75005, Paris, France.
Mirabeau O; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
Karlins E; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Rubio RA; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU, 80337, Munich, Germany.
Zaidi S; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
Grossetete-Lalami S; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
Ballet S; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.; Unité de Génétique Somatique, Institut Curie, Centre Hospitalier, 75005, Paris, France.
Lapouble E; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.; Unité de Génétique Somatique, Institut Curie, Centre Hospitalier, 75005, Paris, France.
Laurence V; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
Michon J; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
Pierron G; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.; Unité de Génétique Somatique, Institut Curie, Centre Hospitalier, 75005, Paris, France.
Kovar H; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, 1090, Vienna, Austria.
Gaspar N; Department of Oncology for Child and Adolescent, Institut Gustave Roussy, 94800, Villejuif, France.
Kontny U; Division of Pediatric Hematology Oncology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, 52062, Aachen, Germany.
González-Neira A; Human Genotyping Unit-CeGen, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, 28029, Madrid, Spain.
Picci P; Laboratorio di Oncologia Sperimentale, Istituto Ortopedico Rizzoli di Bologna, 40136, Bologna, Italy.
Alonso J; Unidad de Tumores Sólidos Infantiles, Instituto de Investigación de Enfermedades Raras, Instituto de Salud Carlos III, 28220, Majadahonda, Spain.
Patino-Garcia A; Laboratory of Pediatrics, University of Navarra, University Clinic of Navarra, IdiSNA, 31008, Pamplona, Spain.
Corradini N; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, 69008, Lyon, France.
Bérard PM; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, 69008, Lyon, France.
Freedman ND; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Rothman N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Dagnall CL; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Burdett L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Jones K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Manning M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Wyatt K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Zhou W; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Yeager M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21701, USA.
Cox DG; Centre Léon Bérard, INSERM U1052, 69008, Lyon, France.
Hoover RN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Khan J; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, 20892, USA.
Armstrong GT; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Leisenring WM; Cancer Prevention and Clinical Statistics Programs, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Bhatia S; Institute for Cancer Outcomes and Survivorship, University of Alabama, Birmingham, AL, 35294, USA.
Robison LL; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Kulozik AE; University Children's Hospital of Heidelberg, 69120, Heidelberg, Germany.
Kriebel J; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, 85764, Germany.
Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, 80333, Munich, Germany.
Metzler M; University Children's Hospital of Erlangen, 91054, Erlangen, Germany.
Hartmann W; Gerhard-Domagk Institute of Pathology, University Hospital of Münster, 48149, Münster, Germany.
Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU, Munich, 80539, Germany.
Kirchner T; German Consortium for Cancer Research (DKTK), 69120, Heidelberg, Germany.; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Institute of Pathology, Faculty of Medicine, LMU, 80337, Munich, Germany.
Dirksen U; University Children's Hospital of Essen, 45147, Essen, Germany.
Morton LM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Mirabello L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Tucker MA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Tirode F; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France.; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France.
Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA. .
Delattre O; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, 75005, Paris, France. .; SIREDO Oncology Centre, Institut Curie, 75005, Paris, France. .
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Źródło :
Nature communications [Nat Commun] 2018 Aug 09; Vol. 9 (1), pp. 3184. Date of Electronic Publication: 2018 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Profiling*
Genetic Predisposition to Disease*
Genome-Wide Association Study*
Sarcoma, Ewing/*genetics
Alleles ; Cell Cycle Proteins/genetics ; Cell Proliferation/genetics ; DNA-Binding Proteins/genetics ; European Continental Ancestry Group ; Gene Expression Regulation, Neoplastic ; Genotype ; Homeodomain Proteins/genetics ; Humans ; Oncogene Proteins, Fusion/genetics ; Polymorphism, Single Nucleotide ; Proto-Oncogene Protein c-fli-1/genetics ; Quality Control ; Quantitative Trait Loci ; RNA-Binding Protein EWS/genetics ; Risk ; Sarcoma, Ewing/ethnology ; Transcription Factors/genetics ; Zebrafish Proteins
Czasopismo naukowe
Tytuł :
Activated ALK signals through the ERK-ETV5-RET pathway to drive neuroblastoma oncogenesis.
Autorzy :
Lopez-Delisle L; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Pierre-Eugène C; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Louis-Brennetot C; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Surdez D; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Raynal V; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.
Baulande S; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.
Boeva V; Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes UMR-S1016, Paris, France.; Institut Curie, PSL Research University, Inserm U900, Mines ParisTech, Paris, France.
Grossetête-Lalami S; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Combaret V; Centre Léon Bérard, Laboratoire de Recherche Translationnelle, Lyon, France.
Peuchmaur M; Departement of Pathology, AP-HP, Hôpital Universitaire Robert Debré, Paris, France.; Université Diderot Paris 7, Paris Sorbonne Cité, Paris, France.
Delattre O; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Janoueix-Lerosey I; Institut Curie, PSL Research University, Inserm U830, Equipe Labellisée Ligue contre le Cancer, Paris, France. .; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France. .
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Źródło :
Oncogene [Oncogene] 2018 Mar; Vol. 37 (11), pp. 1417-1429. Date of Electronic Publication: 2018 Jan 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gain of Function Mutation*/physiology
Anaplastic Lymphoma Kinase/*genetics
Carcinogenesis/*genetics
Neuroblastoma/*genetics
Anaplastic Lymphoma Kinase/metabolism ; Animals ; Carcinogenesis/pathology ; Cells, Cultured ; DNA-Binding Proteins/physiology ; Female ; HEK293 Cells ; Humans ; MAP Kinase Signaling System/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Nude ; Mice, Transgenic ; Neuroblastoma/pathology ; Proto-Oncogene Proteins c-ret/physiology ; Signal Transduction/genetics ; Transcription Factors/physiology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries.
Autorzy :
Boeva V; Institut Curie, Paris Sciences et Lettres (PSL) Research University, INSERM, U900, Mines-ParisTech, Paris, France.; Institut Cochin, Inserm U1016, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 8104, University Paris Descartes UMR-S1016, Paris, France.
Louis-Brennetot C; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Peltier A; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Durand S; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Pierre-Eugène C; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Raynal V; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.
Etchevers HC; Aix Marseille University, INSERM, Génétique Médicale et Génomique Fonctionnelle (GMGF) UMR S910, Marseille, France.
Thomas S; INSERM U1163, Laboratory of Embryology and Genetics of Congenital Malformations, Paris Descartes - Sorbonne Paris Cité University, Imagine Institute, Paris, France.
Lermine A; Institut Curie, Paris Sciences et Lettres (PSL) Research University, INSERM, U900, Mines-ParisTech, Paris, France.
Daudigeos-Dubus E; Gustave Roussy, Vectorology and Anticancer Therapies, UMR 8203, CNRS, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.
Geoerger B; Gustave Roussy, Vectorology and Anticancer Therapies, UMR 8203, CNRS, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Ludwig-Maximilians-Universität München (LMU), Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Ludwig-Maximilians-Universität München (LMU), Munich, Germany.
Diaz E; High Throughput qPCR Facility, Institut de Biologie de l'École Normale Supérieure (IBENS), PSL Research University, Paris, France.; LPS-ENS, Université Pierre et Marie Curie (UPMC), Université Denis Diderot, CNRS UMR 8550, PSL, Paris, France.
Ducos B; High Throughput qPCR Facility, Institut de Biologie de l'École Normale Supérieure (IBENS), PSL Research University, Paris, France.; LPS-ENS, Université Pierre et Marie Curie (UPMC), Université Denis Diderot, CNRS UMR 8550, PSL, Paris, France.; Laser Microdissection Facility, Center for Interdisciplinary Research in Biology (CIRB) Collège de France, Paris, France.
Surdez D; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Carcaboso AM; Institut de Recerca Sant Joan de Deu, Barcelona, Spain.
Medvedeva I; Institut Cochin, Inserm U1016, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 8104, University Paris Descartes UMR-S1016, Paris, France.
Deller T; Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe University Frankfurt, Frankfurt am Main, Germany.
Combaret V; Centre Léon Bérard, Laboratoire de Recherche Translationnelle, Lyon, France.
Lapouble E; Institut Curie, Unité de Génétique Somatique, Paris, France.
Pierron G; Institut Curie, Unité de Génétique Somatique, Paris, France.
Grossetête-Lalami S; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.
Baulande S; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.
Schleiermacher G; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Laboratory Recherche Translationnelle en Oncologie Pédiatrique (RTOP), Laboratoire 'Gilles Thomas', Institut Curie, Paris, France.; Department of Translational Research, Institut Curie, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Barillot E; Institut Curie, Paris Sciences et Lettres (PSL) Research University, INSERM, U900, Mines-ParisTech, Paris, France.
Rohrer H; Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe University Frankfurt, Frankfurt am Main, Germany.
Delattre O; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
Janoueix-Lerosey I; Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France.; SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France.
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Źródło :
Nature genetics [Nat Genet] 2017 Sep; Vol. 49 (9), pp. 1408-1413. Date of Electronic Publication: 2017 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Lineage/*genetics
Gene Expression Regulation, Neoplastic/*genetics
Neuroblastoma/*genetics
Transcription Factors/*genetics
Animals ; Blotting, Western ; Cell Line, Tumor/classification ; Cell Lineage/drug effects ; Doxycycline/pharmacology ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic/drug effects ; Genetic Heterogeneity ; HEK293 Cells ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Humans ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID ; Neuroblastoma/drug therapy ; Neuroblastoma/metabolism ; RNA Interference ; RNAi Therapeutics ; Reverse Transcriptase Polymerase Chain Reaction ; Single-Cell Analysis ; Transcription Factors/metabolism ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł :
Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations.
Autorzy :
Tirode F; INSERM U830, Laboratory of Genetics and Cancer Biology, Institut Curie, Paris, France. Centre de Recherche, Institut Curie, Paris, France.
Surdez D; INSERM U830, Laboratory of Genetics and Cancer Biology, Institut Curie, Paris, France. Centre de Recherche, Institut Curie, Paris, France.
Ma X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Parker M; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Le Deley MC; Departement d'Epidémiologie et de Biostatistiques, Gustave Roussy, Villejuif, France.
Bahrami A; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Zhang Z; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Lapouble E; Unité de Génétique Somatique, Centre Hospitalier, Institut Curie, Paris, France.
Grossetête-Lalami S; INSERM U830, Laboratory of Genetics and Cancer Biology, Institut Curie, Paris, France. Centre de Recherche, Institut Curie, Paris, France.
Rusch M; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Reynaud S; Unité de Génétique Somatique, Centre Hospitalier, Institut Curie, Paris, France.
Rio-Frio T; Centre de Recherche, Institut Curie, Paris, France.
Hedlund E; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Wu G; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Chen X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Pierron G; Unité de Génétique Somatique, Centre Hospitalier, Institut Curie, Paris, France.
Oberlin O; Departement de Pédiatrie, Gustave Roussy, Villejuif, France.
Zaidi S; INSERM U830, Laboratory of Genetics and Cancer Biology, Institut Curie, Paris, France. Centre de Recherche, Institut Curie, Paris, France.
Lemmon G; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Gupta P; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Vadodaria B; The Pediatric Cancer Genome Laboratory, St. Jude Children's Research Hospital, Memphis, Tennessee.
Easton J; The Pediatric Cancer Genome Laboratory, St. Jude Children's Research Hospital, Memphis, Tennessee.
Gut M; Centro Nacional de Análisis Genómico (CNAG), Barcelona, Spain.
Ding L; Department of Genetics, The Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, Missouri. Department of Medicine, The Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, Missouri. Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, Missouri.
Mardis ER; Department of Genetics, The Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, Missouri. Department of Medicine, The Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, Missouri. Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, Missouri.
Wilson RK; Department of Genetics, The Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, Missouri. Department of Medicine, The Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, Missouri. Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, Missouri.
Shurtleff S; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Laurence V; Département d'Oncologie Medicale, Adolescents et Jeunes Adultes, Centre Hospitalier, Institut Curie, Paris, France.
Michon J; Département d'Oncologie Pediatrique, Adolescents et Jeunes Adultes, Centre Hospitalier, Institut Curie, Paris, France.
Marec-Bérard P; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, Lyon, France.
Gut I; Centro Nacional de Análisis Genómico (CNAG), Barcelona, Spain.
Downing J; The Pediatric Cancer Genome Laboratory, St. Jude Children's Research Hospital, Memphis, Tennessee.
Dyer M; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee. Howard Hughes Medical Institute, Chevy Chase, Maryland.
Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee. .
Delattre O; INSERM U830, Laboratory of Genetics and Cancer Biology, Institut Curie, Paris, France. Centre de Recherche, Institut Curie, Paris, France. .
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Corporate Authors :
St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project and the International Cancer Genome Consortium
Źródło :
Cancer discovery [Cancer Discov] 2014 Nov; Vol. 4 (11), pp. 1342-53. Date of Electronic Publication: 2014 Sep 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Nuclear/*genetics
Bone Neoplasms/*genetics
Sarcoma, Ewing/*genetics
Tumor Suppressor Protein p53/*genetics
Cell Line, Tumor ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; DNA, Neoplasm/genetics ; Genomics ; Humans ; Mutation ; Prognosis ; Sequence Analysis, DNA
Czasopismo naukowe
    Wyświetlanie 1-11 z 11

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